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Overview

ID MAG01747
Name HKD1_bin.66
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JALORV01
Species
Assembly information
Completeness (%) 84.55
Contamination (%) 3.95
GC content (%) 67.0
N50 (bp) 33,033
Genome size (bp) 3,346,155

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3100

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1006223_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1409.0
HKD1_k127_1006223_1 Tetratricopeptide repeat - - - 0.0 1144.0
HKD1_k127_1006223_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007998 263.0
HKD1_k127_1006223_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002672 263.0
HKD1_k127_1006223_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003372 254.0
HKD1_k127_1006223_13 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004235 250.0
HKD1_k127_1006223_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005034 263.0
HKD1_k127_1006223_16 - - - - 0.000000000000000000000000000000000000000000000000000000000001774 216.0
HKD1_k127_1006223_17 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000001759 197.0
HKD1_k127_1006223_18 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000006729 194.0
HKD1_k127_1006223_19 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000001538 187.0
HKD1_k127_1006223_2 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 1.67e-321 1055.0
HKD1_k127_1006223_20 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000647 136.0
HKD1_k127_1006223_21 Autotransporter beta-domain - - - 0.000000000000000000000000000000008053 150.0
HKD1_k127_1006223_22 - - - - 0.0000000000000000000000000000005655 127.0
HKD1_k127_1006223_23 LytTr DNA-binding domain - - - 0.000000000000000004032 87.0
HKD1_k127_1006223_3 Tetratricopeptide repeat - - - 2.061e-194 628.0
HKD1_k127_1006223_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 435.0
HKD1_k127_1006223_5 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 420.0
HKD1_k127_1006223_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
HKD1_k127_1006223_7 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 330.0
HKD1_k127_1006223_8 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 316.0
HKD1_k127_1006223_9 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 309.0
HKD1_k127_1013571_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1700.0
HKD1_k127_1013571_1 Heavy metal transport detoxification protein K17686 - 3.6.3.54 7.427e-256 814.0
HKD1_k127_1013571_10 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000000000000000000000002822 198.0
HKD1_k127_1013571_11 Domain of unknown function (DUF1993) - - - 0.00000000000000000000000000000000000000000000000000001359 198.0
HKD1_k127_1013571_12 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000002757 173.0
HKD1_k127_1013571_13 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000008679 153.0
HKD1_k127_1013571_14 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000002976 139.0
HKD1_k127_1013571_15 Domain of unknown function (DUF1857) - - - 0.0000000000000000000000000000003254 136.0
HKD1_k127_1013571_16 - - - - 0.000000000000000000000000000001559 129.0
HKD1_k127_1013571_17 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000003059 126.0
HKD1_k127_1013571_18 - - - - 0.000004639 51.0
HKD1_k127_1013571_19 - - - - 0.00002887 56.0
HKD1_k127_1013571_2 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 622.0
HKD1_k127_1013571_3 PrpF protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 466.0
HKD1_k127_1013571_4 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 407.0
HKD1_k127_1013571_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 349.0
HKD1_k127_1013571_6 coenzyme F420-1:gamma-L-glutamate ligase activity K19285,K19286 - 1.5.1.38,1.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 348.0
HKD1_k127_1013571_7 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 314.0
HKD1_k127_1013571_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006929 252.0
HKD1_k127_1013571_9 Nuclear protein SET K07117 - - 0.00000000000000000000000000000000000000000000000000000000001904 212.0
HKD1_k127_1020301_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 509.0
HKD1_k127_1020301_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000002929 129.0
HKD1_k127_1022455_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1133.0
HKD1_k127_1022455_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1049.0
HKD1_k127_1022455_10 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.029e-203 641.0
HKD1_k127_1022455_11 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 1.817e-202 646.0
HKD1_k127_1022455_12 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 612.0
HKD1_k127_1022455_13 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 607.0
HKD1_k127_1022455_14 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 610.0
HKD1_k127_1022455_15 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 596.0
HKD1_k127_1022455_16 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 529.0
HKD1_k127_1022455_17 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 502.0
HKD1_k127_1022455_18 Belongs to the FBPase class 1 family K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 510.0
HKD1_k127_1022455_19 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 502.0
HKD1_k127_1022455_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.318e-303 944.0
HKD1_k127_1022455_20 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 484.0
HKD1_k127_1022455_21 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 465.0
HKD1_k127_1022455_22 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 400.0
HKD1_k127_1022455_23 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 378.0
HKD1_k127_1022455_25 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 378.0
HKD1_k127_1022455_26 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 358.0
HKD1_k127_1022455_27 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 337.0
HKD1_k127_1022455_28 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 325.0
HKD1_k127_1022455_29 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
HKD1_k127_1022455_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 8.156e-299 935.0
HKD1_k127_1022455_30 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 297.0
HKD1_k127_1022455_31 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003281 282.0
HKD1_k127_1022455_32 Serine hydrolase (FSH1) K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
HKD1_k127_1022455_33 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001241 289.0
HKD1_k127_1022455_34 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002584 277.0
HKD1_k127_1022455_35 Protein of unknown function (DUF2868) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003981 287.0
HKD1_k127_1022455_36 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001912 271.0
HKD1_k127_1022455_37 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002879 272.0
HKD1_k127_1022455_38 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001195 277.0
HKD1_k127_1022455_39 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002679 268.0
HKD1_k127_1022455_4 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.602e-256 802.0
HKD1_k127_1022455_40 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005703 270.0
HKD1_k127_1022455_41 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001671 250.0
HKD1_k127_1022455_42 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000001909 240.0
HKD1_k127_1022455_43 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003831 238.0
HKD1_k127_1022455_44 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000003862 250.0
HKD1_k127_1022455_45 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000008029 231.0
HKD1_k127_1022455_46 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000000005246 228.0
HKD1_k127_1022455_47 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000525 217.0
HKD1_k127_1022455_48 - - - - 0.0000000000000000000000000000000000000000000000000000000000006639 222.0
HKD1_k127_1022455_49 Diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000003243 222.0
HKD1_k127_1022455_5 AsmA family - - - 1.175e-233 767.0
HKD1_k127_1022455_50 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000004275 197.0
HKD1_k127_1022455_51 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005555 196.0
HKD1_k127_1022455_52 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000001393 197.0
HKD1_k127_1022455_53 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000587 197.0
HKD1_k127_1022455_54 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000009004 183.0
HKD1_k127_1022455_55 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000002673 187.0
HKD1_k127_1022455_56 Haem-degrading - - - 0.000000000000000000000000000000000000000000000003574 181.0
HKD1_k127_1022455_57 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000002025 196.0
HKD1_k127_1022455_58 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000002104 184.0
HKD1_k127_1022455_59 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000000004106 161.0
HKD1_k127_1022455_6 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.063e-231 736.0
HKD1_k127_1022455_60 diguanylate cyclase - - - 0.0000000000000000000000000000000000000008675 166.0
HKD1_k127_1022455_61 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000001588 153.0
HKD1_k127_1022455_62 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000003046 146.0
HKD1_k127_1022455_63 Uroporphyrinogen-III synthase HemD - - - 0.000000000000000000000000000001105 139.0
HKD1_k127_1022455_64 membrane - - - 0.0000000000000000000000000000917 118.0
HKD1_k127_1022455_65 Histidine kinase - - - 0.000000000000000000001146 108.0
HKD1_k127_1022455_66 ATPase MipZ K03496 - - 0.0000000000002303 75.0
HKD1_k127_1022455_67 - - - - 0.0000000000008042 78.0
HKD1_k127_1022455_68 - - - - 0.00000000001071 69.0
HKD1_k127_1022455_69 regulation of single-species biofilm formation - - - 0.0004874 46.0
HKD1_k127_1022455_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 3.362e-219 694.0
HKD1_k127_1022455_8 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.36e-211 670.0
HKD1_k127_1022455_9 argininosuccinate lyase K01755 - 4.3.2.1 9.643e-211 664.0
HKD1_k127_1028484_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5.158e-313 975.0
HKD1_k127_1028484_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.884e-215 674.0
HKD1_k127_1033144_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 373.0
HKD1_k127_1033144_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000493 259.0
HKD1_k127_1033144_2 PFAM Ankyrin K06867 - - 0.00000000000000000000000000000000000000000000000000000000016 215.0
HKD1_k127_1033144_3 - - - - 0.0000000000002908 72.0
HKD1_k127_1118701_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000003131 131.0
HKD1_k127_1118701_1 - - - - 0.0000000000000000002025 90.0
HKD1_k127_1165272_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1298.0
HKD1_k127_1165272_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 602.0
HKD1_k127_1165272_10 - - - - 0.0000000000000000000000000000000000000000001005 166.0
HKD1_k127_1165272_11 PFAM GCN5-related N-acetyltransferase K03825 - - 0.000000000000000000000000000000000000000378 156.0
HKD1_k127_1165272_12 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000001105 128.0
HKD1_k127_1165272_13 - - - - 0.000000000000000000000000003705 114.0
HKD1_k127_1165272_14 FixH family K09926 - - 0.00000000000000000000002016 110.0
HKD1_k127_1165272_15 Cbb3-type cytochrome oxidase K00407 - - 0.0000000000001418 72.0
HKD1_k127_1165272_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 595.0
HKD1_k127_1165272_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 581.0
HKD1_k127_1165272_4 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 554.0
HKD1_k127_1165272_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 397.0
HKD1_k127_1165272_6 Bacterial regulatory proteins, crp family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 357.0
HKD1_k127_1165272_7 cytochrome C oxidase K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 330.0
HKD1_k127_1165272_8 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000009521 222.0
HKD1_k127_1165272_9 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000001379 174.0
HKD1_k127_1167593_0 Type IV pili methyl-accepting chemotaxis transducer N-term K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 414.0
HKD1_k127_1167593_1 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007932 238.0
HKD1_k127_1167593_2 PFAM response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000000000000000000000000007131 235.0
HKD1_k127_1167593_3 CheW-like domain K02659 - - 0.000000000000000000000000000000000000000000000000000000000000008624 220.0
HKD1_k127_1167593_4 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000415 74.0
HKD1_k127_1176945_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.247e-220 692.0
HKD1_k127_1176945_1 EthD domain - - - 0.00000000000000000000000000000000000000006153 159.0
HKD1_k127_1176945_2 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000001861 77.0
HKD1_k127_1189381_0 Alkyl hydroperoxide reductase K03387 - - 3.564e-264 822.0
HKD1_k127_1189381_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 456.0
HKD1_k127_1189381_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000004577 251.0
HKD1_k127_1189381_11 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000276 247.0
HKD1_k127_1189381_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000003015 241.0
HKD1_k127_1189381_13 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000001594 224.0
HKD1_k127_1189381_14 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000005374 216.0
HKD1_k127_1189381_15 TPM domain - - - 0.000000000000000000000000000000000000000000000009194 176.0
HKD1_k127_1189381_16 Redoxin - - - 0.00000000000000000000000000000000000000000000003218 175.0
HKD1_k127_1189381_17 TPM domain K06872 - - 0.0000000000000000000000000000000004722 136.0
HKD1_k127_1189381_18 Polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000006067 128.0
HKD1_k127_1189381_19 Domain of unknown function (DUF4266) - - - 0.0000000000000000002293 91.0
HKD1_k127_1189381_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 346.0
HKD1_k127_1189381_3 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 349.0
HKD1_k127_1189381_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 334.0
HKD1_k127_1189381_5 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 323.0
HKD1_k127_1189381_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 320.0
HKD1_k127_1189381_7 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 323.0
HKD1_k127_1189381_8 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 288.0
HKD1_k127_1189381_9 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002866 295.0
HKD1_k127_1190293_0 Malic enzyme K00029 - 1.1.1.40 0.0 1134.0
HKD1_k127_1190293_1 Belongs to the transketolase family K00615 - 2.2.1.1 1.008e-288 902.0
HKD1_k127_1190293_10 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 349.0
HKD1_k127_1190293_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
HKD1_k127_1190293_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000003287 269.0
HKD1_k127_1190293_13 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000004368 234.0
HKD1_k127_1190293_14 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000000001871 223.0
HKD1_k127_1190293_15 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000002156 227.0
HKD1_k127_1190293_16 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000008865 204.0
HKD1_k127_1190293_17 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000002575 191.0
HKD1_k127_1190293_18 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000002812 202.0
HKD1_k127_1190293_19 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000001241 179.0
HKD1_k127_1190293_2 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 3.865e-271 840.0
HKD1_k127_1190293_20 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000007284 167.0
HKD1_k127_1190293_21 ribonuclease K01167 - 3.1.27.3 0.00000000000000000000000000000000000001693 148.0
HKD1_k127_1190293_22 mRNA catabolic process - - - 0.0000000000000000000000000000000000007418 149.0
HKD1_k127_1190293_23 Redoxin domain protein - - - 0.00000000000000000000000000000000001682 145.0
HKD1_k127_1190293_24 KTSC domain - - - 0.00000000000000000000000000002502 117.0
HKD1_k127_1190293_25 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000002402 119.0
HKD1_k127_1190293_26 Barstar (barnase inhibitor) - - - 0.00000000000000000000209 104.0
HKD1_k127_1190293_27 Rhomboid family - - - 0.0000000000000000001497 99.0
HKD1_k127_1190293_28 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000009593 76.0
HKD1_k127_1190293_3 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.802e-243 756.0
HKD1_k127_1190293_4 RNB K01147 - 3.1.13.1 1.909e-223 711.0
HKD1_k127_1190293_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 610.0
HKD1_k127_1190293_6 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 602.0
HKD1_k127_1190293_7 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 594.0
HKD1_k127_1190293_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 467.0
HKD1_k127_1190293_9 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 360.0
HKD1_k127_1195570_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.365e-275 855.0
HKD1_k127_1195570_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 566.0
HKD1_k127_1195570_2 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 477.0
HKD1_k127_1195570_3 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 355.0
HKD1_k127_1195570_4 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 340.0
HKD1_k127_1195570_5 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000004748 127.0
HKD1_k127_1229999_0 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 526.0
HKD1_k127_1229999_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 482.0
HKD1_k127_1229999_10 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000006401 169.0
HKD1_k127_1229999_11 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000000000000001167 158.0
HKD1_k127_1229999_12 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000209 145.0
HKD1_k127_1229999_13 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000007405 115.0
HKD1_k127_1229999_14 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000009065 104.0
HKD1_k127_1229999_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 465.0
HKD1_k127_1229999_3 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 394.0
HKD1_k127_1229999_4 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 357.0
HKD1_k127_1229999_5 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
HKD1_k127_1229999_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001547 253.0
HKD1_k127_1229999_7 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006045 246.0
HKD1_k127_1229999_8 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000005875 201.0
HKD1_k127_1229999_9 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000001386 185.0
HKD1_k127_1257162_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1523.0
HKD1_k127_1257162_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.539e-247 783.0
HKD1_k127_1257162_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000004633 223.0
HKD1_k127_1257162_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000003085 210.0
HKD1_k127_1257162_12 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000006776 154.0
HKD1_k127_1257162_13 Helix-hairpin-helix motif - - - 0.000000000000000002941 96.0
HKD1_k127_1257162_14 Protein of unknown function (DUF4241) - - - 0.000000000000001126 86.0
HKD1_k127_1257162_17 Protein of unknown function (DUF3106) - - - 0.0000008759 59.0
HKD1_k127_1257162_2 COG0457 FOG TPR repeat - - - 5.973e-238 750.0
HKD1_k127_1257162_3 response regulator K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 402.0
HKD1_k127_1257162_4 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 410.0
HKD1_k127_1257162_5 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 384.0
HKD1_k127_1257162_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 344.0
HKD1_k127_1257162_7 Phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000497 260.0
HKD1_k127_1257162_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000002338 247.0
HKD1_k127_1257162_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000002987 264.0
HKD1_k127_1341237_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 344.0
HKD1_k127_1341237_1 hmm pf02371 K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 310.0
HKD1_k127_1341237_2 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
HKD1_k127_1341237_3 Diguanylate cyclase - - - 0.0000000000000000003612 88.0
HKD1_k127_1341237_4 Protein of unknown function (DUF1289) K06938 - - 0.000000008228 59.0
HKD1_k127_1352834_0 C-terminal region of peptidase_M24 K01262 - 3.4.11.9 1.316e-253 798.0
HKD1_k127_1352834_1 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 517.0
HKD1_k127_1352834_10 - - - - 0.00000000000000000000000000008212 131.0
HKD1_k127_1352834_11 cell adhesion involved in biofilm formation - - - 0.000000000000000000005768 104.0
HKD1_k127_1352834_12 protein, possibly involved in nitrogen fixation - - - 0.00009764 46.0
HKD1_k127_1352834_2 Belongs to the heme-copper respiratory oxidase family K00404 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 362.0
HKD1_k127_1352834_3 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 378.0
HKD1_k127_1352834_4 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 319.0
HKD1_k127_1352834_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 282.0
HKD1_k127_1352834_6 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000005917 174.0
HKD1_k127_1352834_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000001312 154.0
HKD1_k127_1352834_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000002609 142.0
HKD1_k127_1352834_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000001182 147.0
HKD1_k127_137151_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 317.0
HKD1_k127_137151_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000004249 202.0
HKD1_k127_1391884_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1775.0
HKD1_k127_1391884_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 429.0
HKD1_k127_1391884_2 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000001751 251.0
HKD1_k127_1391884_3 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000000000000000000000000000000000000003263 158.0
HKD1_k127_1391884_4 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000000000000000000000000000000000000003306 151.0
HKD1_k127_1439857_0 histidine kinase A domain protein - - - 0.0 1303.0
HKD1_k127_1439857_1 DNA polymerase III K02342 - 2.7.7.7 8.318e-282 883.0
HKD1_k127_1439857_10 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000004268 187.0
HKD1_k127_1439857_11 protein domain associated with - - - 0.000000000000000000000000000000000000000013 158.0
HKD1_k127_1439857_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000163 135.0
HKD1_k127_1439857_13 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000002661 135.0
HKD1_k127_1439857_14 - - - - 0.00000000000000008782 87.0
HKD1_k127_1439857_16 - - - - 0.000006826 56.0
HKD1_k127_1439857_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 7.119e-276 860.0
HKD1_k127_1439857_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 531.0
HKD1_k127_1439857_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 417.0
HKD1_k127_1439857_5 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 396.0
HKD1_k127_1439857_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 370.0
HKD1_k127_1439857_7 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 341.0
HKD1_k127_1439857_8 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000431 273.0
HKD1_k127_1439857_9 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000124 204.0
HKD1_k127_1441651_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1099.0
HKD1_k127_1441651_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 3.352e-320 996.0
HKD1_k127_1441651_10 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 385.0
HKD1_k127_1441651_11 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 365.0
HKD1_k127_1441651_12 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 363.0
HKD1_k127_1441651_13 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 344.0
HKD1_k127_1441651_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 342.0
HKD1_k127_1441651_15 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 325.0
HKD1_k127_1441651_16 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 317.0
HKD1_k127_1441651_17 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 303.0
HKD1_k127_1441651_18 Methyltransferase type 12 K03439 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 312.0
HKD1_k127_1441651_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002178 279.0
HKD1_k127_1441651_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.088e-294 922.0
HKD1_k127_1441651_20 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003736 263.0
HKD1_k127_1441651_21 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000005291 260.0
HKD1_k127_1441651_22 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 265.0
HKD1_k127_1441651_23 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000684 243.0
HKD1_k127_1441651_24 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000002426 185.0
HKD1_k127_1441651_25 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000000002771 173.0
HKD1_k127_1441651_26 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000848 170.0
HKD1_k127_1441651_27 - - - - 0.00000000000000000000000000000000000000007899 157.0
HKD1_k127_1441651_28 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000001925 143.0
HKD1_k127_1441651_29 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000001131 138.0
HKD1_k127_1441651_3 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.954e-262 812.0
HKD1_k127_1441651_30 Transcriptional K08365 - - 0.0000000000000000000000000000004129 132.0
HKD1_k127_1441651_31 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000004942 117.0
HKD1_k127_1441651_32 amine dehydrogenase activity K13730 - - 0.000000000000000000000000001138 126.0
HKD1_k127_1441651_33 ATP-independent chaperone mediated protein folding - - - 0.00000000000000001749 89.0
HKD1_k127_1441651_34 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000001234 78.0
HKD1_k127_1441651_35 Protein of unknown function (DUF2933) - - - 0.000000000000001269 82.0
HKD1_k127_1441651_36 member of a two-component regulatory system K02484,K07644 GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000058 74.0
HKD1_k127_1441651_37 - - - - 0.00000000001892 67.0
HKD1_k127_1441651_38 Caspase domain - - - 0.0000001048 63.0
HKD1_k127_1441651_39 - - - - 0.0000002405 55.0
HKD1_k127_1441651_4 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 3.393e-222 700.0
HKD1_k127_1441651_40 Short C-terminal domain - - - 0.000001669 53.0
HKD1_k127_1441651_42 BRO family, N-terminal domain K07741 - - 0.0005415 49.0
HKD1_k127_1441651_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 622.0
HKD1_k127_1441651_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 540.0
HKD1_k127_1441651_7 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 430.0
HKD1_k127_1441651_8 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 434.0
HKD1_k127_1441651_9 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 423.0
HKD1_k127_1451367_0 Protein involved in receptor activity and transport K02014 - - 2.918e-295 926.0
HKD1_k127_1451367_10 Oxidoreductase - - - 0.0000000000000000000000000000000000000006991 154.0
HKD1_k127_1451367_11 protein TIM barrel - - - 0.000000000000000000000000008706 124.0
HKD1_k127_1451367_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 359.0
HKD1_k127_1451367_4 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 313.0
HKD1_k127_1451367_5 Amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000001615 275.0
HKD1_k127_1451367_6 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001518 243.0
HKD1_k127_1451367_7 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000002716 247.0
HKD1_k127_1451367_8 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000001096 188.0
HKD1_k127_1451367_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000002909 175.0
HKD1_k127_1456942_0 Protein involved in UDP-N-acetylmuramate dehydrogenase activity and amino sugar metabolic process K05797 - 1.17.99.1 1.817e-202 646.0
HKD1_k127_1456942_1 KR domain - - - 0.000000000000000000000000000000000000000000003323 169.0
HKD1_k127_1456942_2 succinate dehydrogenase K00244 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.3.5.4 0.0000000000000000001353 91.0
HKD1_k127_1456942_3 Cytochrome c K00406 - - 0.000000000000000002002 89.0
HKD1_k127_1482875_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 4.126e-199 632.0
HKD1_k127_1482875_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 582.0
HKD1_k127_1482875_10 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000024 245.0
HKD1_k127_1482875_11 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001609 231.0
HKD1_k127_1482875_12 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000001056 214.0
HKD1_k127_1482875_13 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000001092 202.0
HKD1_k127_1482875_14 PFAM DinB family - - - 0.000000000000000000000000000000000000000000000000000000139 204.0
HKD1_k127_1482875_15 Pfam:N_methyl_2 K02456 - - 0.0000000000000000000000000000000000000000000003581 171.0
HKD1_k127_1482875_16 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000005836 161.0
HKD1_k127_1482875_17 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000009107 166.0
HKD1_k127_1482875_18 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000003296 145.0
HKD1_k127_1482875_19 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000001266 144.0
HKD1_k127_1482875_2 type II secretion system protein E K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 583.0
HKD1_k127_1482875_20 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000007638 133.0
HKD1_k127_1482875_21 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000008382 145.0
HKD1_k127_1482875_22 Histidine kinase - - - 0.000000000000000000000000000000005817 141.0
HKD1_k127_1482875_23 Cyclase dehydrase - - - 0.000000000000000000000000000001562 126.0
HKD1_k127_1482875_24 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000000000000003883 113.0
HKD1_k127_1482875_25 - - - - 0.000000000000000000000004834 109.0
HKD1_k127_1482875_26 - - - - 0.0000000000000000000002317 105.0
HKD1_k127_1482875_27 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000000000000000002716 100.0
HKD1_k127_1482875_28 - - - - 0.000000000000000000008678 102.0
HKD1_k127_1482875_29 - - - - 0.00000000000000001983 91.0
HKD1_k127_1482875_3 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 577.0
HKD1_k127_1482875_30 Cytochrome c K08738 - - 0.00000000000003954 77.0
HKD1_k127_1482875_31 carbon utilization - - - 0.000000000000382 77.0
HKD1_k127_1482875_32 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000141 66.0
HKD1_k127_1482875_33 CAAX protease self-immunity K07052 - - 0.0000000008015 68.0
HKD1_k127_1482875_34 ATP synthase (F/14-kDa) subunit - - - 0.000001625 53.0
HKD1_k127_1482875_36 - - - - 0.0009509 49.0
HKD1_k127_1482875_4 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 547.0
HKD1_k127_1482875_5 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 437.0
HKD1_k127_1482875_6 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 415.0
HKD1_k127_1482875_7 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 409.0
HKD1_k127_1482875_8 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003473 286.0
HKD1_k127_1482875_9 helix_turn_helix, Lux Regulon K14979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009137 264.0
HKD1_k127_150813_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 336.0
HKD1_k127_150813_1 Major Facilitator K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 336.0
HKD1_k127_150813_2 PFAM Cys Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000001136 197.0
HKD1_k127_150813_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000367 73.0
HKD1_k127_1569679_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 442.0
HKD1_k127_1569679_1 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000001464 151.0
HKD1_k127_1569679_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000002313 142.0
HKD1_k127_1579429_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 478.0
HKD1_k127_1579429_1 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 372.0
HKD1_k127_1610793_0 CHAD domain - - - 0.000000000000000000000000000000000000000000000000000002627 209.0
HKD1_k127_1610793_1 outer membrane usher protein K07347 - - 0.00000000000000000000003512 106.0
HKD1_k127_1610793_2 Spore Coat - - - 0.000000004959 64.0
HKD1_k127_16648_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000004776 236.0
HKD1_k127_16648_1 ANTAR K22010 - - 0.0000000000000000000000000000000000000000000000003498 182.0
HKD1_k127_16648_2 - - - - 0.0000000000000007673 84.0
HKD1_k127_1759183_0 transposase K07481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 426.0
HKD1_k127_181874_0 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 302.0
HKD1_k127_1890570_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.091e-275 854.0
HKD1_k127_1890570_1 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 312.0
HKD1_k127_190696_0 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 356.0
HKD1_k127_190696_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 337.0
HKD1_k127_190696_2 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 297.0
HKD1_k127_190696_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000001524 229.0
HKD1_k127_190696_4 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000007991 226.0
HKD1_k127_190696_5 Auxin binding protein - - - 0.000000000000000000000000000000000000003459 151.0
HKD1_k127_190696_6 Cold shock K03704 - - 0.000000000000000000000000921 111.0
HKD1_k127_190696_7 - - - - 0.0000000000000000001425 97.0
HKD1_k127_2010056_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 597.0
HKD1_k127_2010056_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 467.0
HKD1_k127_2010056_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006748 272.0
HKD1_k127_2010056_3 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 285.0
HKD1_k127_2010056_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004496 267.0
HKD1_k127_2024360_0 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
HKD1_k127_2024360_1 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.000000000000000000000000000000000000000000000000000000000000000000001129 244.0
HKD1_k127_2024360_2 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009279,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016409,GO:0016416,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044462,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.251 0.000000000000000000000000000000000000000000000000000000000000000000002791 250.0
HKD1_k127_2024360_3 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000002618 226.0
HKD1_k127_2024360_4 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000005283 78.0
HKD1_k127_2024360_5 - - - - 0.000000006416 65.0
HKD1_k127_2029608_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 323.0
HKD1_k127_2029608_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000001916 108.0
HKD1_k127_2029608_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000008814 69.0
HKD1_k127_2034806_0 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 278.0
HKD1_k127_2034806_1 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000482 182.0
HKD1_k127_2034806_2 Flavin reductase like domain - - - 0.0000000000000000000000000000000001368 135.0
HKD1_k127_2040096_0 Sodium:dicarboxylate symporter family - - - 1.125e-201 637.0
HKD1_k127_2040096_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 561.0
HKD1_k127_2040096_2 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002052 254.0
HKD1_k127_2045218_0 Branched-chain amino acid transport system / permease component K01997,K01998 - - 3.79e-205 655.0
HKD1_k127_2045218_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 5.099e-205 643.0
HKD1_k127_2045218_10 Threonyl alanyl tRNA synthetase K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 262.0
HKD1_k127_2045218_11 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
HKD1_k127_2045218_12 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007221 248.0
HKD1_k127_2045218_13 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000001825 261.0
HKD1_k127_2045218_14 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000003985 241.0
HKD1_k127_2045218_15 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000001667 216.0
HKD1_k127_2045218_16 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000002811 201.0
HKD1_k127_2045218_17 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000009031 184.0
HKD1_k127_2045218_18 acyl-coA-binding protein - - - 0.000000000000000000000000000003574 138.0
HKD1_k127_2045218_19 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000001579 86.0
HKD1_k127_2045218_2 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 613.0
HKD1_k127_2045218_3 de-polymerase K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 562.0
HKD1_k127_2045218_4 Sodium proton antiporter, NhaD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 565.0
HKD1_k127_2045218_5 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 498.0
HKD1_k127_2045218_6 Pyridoxal-phosphate dependent enzyme K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 475.0
HKD1_k127_2045218_7 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 398.0
HKD1_k127_2045218_8 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 382.0
HKD1_k127_2045218_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 337.0
HKD1_k127_2109681_0 FtsX-like permease family K02004 - - 8.789e-281 885.0
HKD1_k127_2109681_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 467.0
HKD1_k127_212774_0 Aminotransferase class I and II K09758 - 4.1.1.12 1.147e-224 703.0
HKD1_k127_212774_1 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000000000000000008602 181.0
HKD1_k127_2128083_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1109.0
HKD1_k127_2128083_1 metal-dependent hydrolase with the TIM-barrel fold - - - 2.905e-243 765.0
HKD1_k127_2128083_10 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000002504 228.0
HKD1_k127_2128083_11 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000005546 191.0
HKD1_k127_2128083_12 AsnC family transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000000001607 188.0
HKD1_k127_2128083_13 - - - - 0.000000000004838 70.0
HKD1_k127_2128083_14 amino acid transport K02029 - - 0.00000008907 55.0
HKD1_k127_2128083_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 602.0
HKD1_k127_2128083_3 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 590.0
HKD1_k127_2128083_4 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 547.0
HKD1_k127_2128083_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 521.0
HKD1_k127_2128083_6 hydroxypyruvate reductase K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 524.0
HKD1_k127_2128083_7 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 441.0
HKD1_k127_2128083_8 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 370.0
HKD1_k127_2128083_9 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 352.0
HKD1_k127_2146972_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.278e-312 962.0
HKD1_k127_2146972_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000003387 194.0
HKD1_k127_2146972_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000002269 84.0
HKD1_k127_2266850_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 2.446e-321 992.0
HKD1_k127_2266850_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 532.0
HKD1_k127_2266850_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000004035 52.0
HKD1_k127_2266850_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 467.0
HKD1_k127_2266850_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 295.0
HKD1_k127_2266850_4 Domain of Unknown function (DUF542) - - - 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
HKD1_k127_2266850_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000005325 195.0
HKD1_k127_2266850_6 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000009522 168.0
HKD1_k127_2266850_7 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000004636 138.0
HKD1_k127_2266850_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000000627 59.0
HKD1_k127_2528255_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 569.0
HKD1_k127_2528255_1 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000006477 205.0
HKD1_k127_2566806_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 2.152e-228 729.0
HKD1_k127_2566806_1 Adenylate cyclase - - - 3.157e-224 713.0
HKD1_k127_2566806_10 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000001093 150.0
HKD1_k127_2566806_11 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000009084 132.0
HKD1_k127_2566806_12 membrane - - - 0.0005208 49.0
HKD1_k127_2566806_2 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 403.0
HKD1_k127_2566806_3 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 403.0
HKD1_k127_2566806_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
HKD1_k127_2566806_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000001613 207.0
HKD1_k127_2566806_6 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000003389 207.0
HKD1_k127_2566806_7 CHRD domain - - - 0.000000000000000000000000000000000000000000000000000000005626 212.0
HKD1_k127_2566806_8 Flavodoxin domain K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.000000000000000000000000000000000000000000000000007206 187.0
HKD1_k127_2566806_9 OsmC-like protein - - - 0.000000000000000000000000000000000000000000002392 168.0
HKD1_k127_2618020_0 Belongs to the UPF0753 family K09822 - - 0.0 1420.0
HKD1_k127_2618020_1 Proton-conducting membrane transporter K05577 - 1.6.5.3 3.401e-236 739.0
HKD1_k127_2618020_10 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000002128 183.0
HKD1_k127_2618020_11 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001463 171.0
HKD1_k127_2618020_12 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000006581 158.0
HKD1_k127_2618020_13 Transposase, Mutator family - - - 0.0000000000000000000000000000000000004408 141.0
HKD1_k127_2618020_14 Transposase, Mutator family - - - 0.000000000000002363 83.0
HKD1_k127_2618020_15 NAD-dependent epimerase dehydratase - - - 0.0000000000002522 73.0
HKD1_k127_2618020_2 FAD dependent oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 562.0
HKD1_k127_2618020_3 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 531.0
HKD1_k127_2618020_4 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 502.0
HKD1_k127_2618020_5 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 415.0
HKD1_k127_2618020_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 306.0
HKD1_k127_2618020_7 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 314.0
HKD1_k127_2618020_8 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001579 255.0
HKD1_k127_2618020_9 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000001869 221.0
HKD1_k127_2733849_0 Tripartite tricarboxylate transporter TctA family - - - 1.529e-245 766.0
HKD1_k127_2733849_1 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 7.035e-220 694.0
HKD1_k127_2733849_10 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000003089 177.0
HKD1_k127_2733849_11 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000007946 136.0
HKD1_k127_2733849_12 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000001709 128.0
HKD1_k127_2733849_13 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000008102 101.0
HKD1_k127_2733849_2 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 575.0
HKD1_k127_2733849_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 548.0
HKD1_k127_2733849_4 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 473.0
HKD1_k127_2733849_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 413.0
HKD1_k127_2733849_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 391.0
HKD1_k127_2733849_7 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 302.0
HKD1_k127_2733849_8 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 297.0
HKD1_k127_2733849_9 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000253 228.0
HKD1_k127_2777635_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2678.0
HKD1_k127_2777635_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 8.526e-199 640.0
HKD1_k127_2777635_10 Belongs to the ABC transporter superfamily K02031 - - 0.00000000001648 64.0
HKD1_k127_2777635_11 Sel1-like repeats. K07126 - - 0.000002161 61.0
HKD1_k127_2777635_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 566.0
HKD1_k127_2777635_3 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 471.0
HKD1_k127_2777635_4 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 412.0
HKD1_k127_2777635_5 (ABC) transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 384.0
HKD1_k127_2777635_6 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 370.0
HKD1_k127_2777635_7 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.0000000000000000000000000000000000000000001177 166.0
HKD1_k127_2777635_8 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000009341 149.0
HKD1_k127_2777635_9 - - - - 0.000000000000000000000000004589 116.0
HKD1_k127_2808812_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.006e-204 644.0
HKD1_k127_2808812_1 Domain of unknown function DUF21 K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 557.0
HKD1_k127_2808812_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 345.0
HKD1_k127_2808812_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 339.0
HKD1_k127_2808812_12 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 338.0
HKD1_k127_2808812_13 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001423 269.0
HKD1_k127_2808812_14 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000007974 222.0
HKD1_k127_2808812_15 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000001282 207.0
HKD1_k127_2808812_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000002275 200.0
HKD1_k127_2808812_17 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000213 201.0
HKD1_k127_2808812_18 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000001344 172.0
HKD1_k127_2808812_19 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000001198 170.0
HKD1_k127_2808812_2 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 521.0
HKD1_k127_2808812_20 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000002445 163.0
HKD1_k127_2808812_21 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000003413 110.0
HKD1_k127_2808812_22 Hsp20/alpha crystallin family - - - 0.00000000000000000000000004479 113.0
HKD1_k127_2808812_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000003525 108.0
HKD1_k127_2808812_24 membrane - - - 0.0000000000000183 78.0
HKD1_k127_2808812_25 CAAX protease self-immunity K07052 - - 0.0004271 50.0
HKD1_k127_2808812_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 518.0
HKD1_k127_2808812_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 465.0
HKD1_k127_2808812_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 475.0
HKD1_k127_2808812_6 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 459.0
HKD1_k127_2808812_7 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 431.0
HKD1_k127_2808812_8 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 394.0
HKD1_k127_2808812_9 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 385.0
HKD1_k127_2826822_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 8.635e-216 684.0
HKD1_k127_2826822_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 568.0
HKD1_k127_2826822_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001303 231.0
HKD1_k127_2826822_11 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000000008236 205.0
HKD1_k127_2826822_12 Prokaryotic cytochrome b561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000002798 196.0
HKD1_k127_2826822_13 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000001794 196.0
HKD1_k127_2826822_14 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000003233 153.0
HKD1_k127_2826822_15 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000002572 123.0
HKD1_k127_2826822_16 HNH endonuclease - - - 0.00000000000000001772 93.0
HKD1_k127_2826822_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000271 74.0
HKD1_k127_2826822_2 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 466.0
HKD1_k127_2826822_3 LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 418.0
HKD1_k127_2826822_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 410.0
HKD1_k127_2826822_5 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 415.0
HKD1_k127_2826822_6 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 385.0
HKD1_k127_2826822_7 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 372.0
HKD1_k127_2826822_8 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 344.0
HKD1_k127_2826822_9 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003104 248.0
HKD1_k127_2836778_0 Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000007779 226.0
HKD1_k127_2836778_1 - - - - 0.000000000000000000000000000000000000000004598 159.0
HKD1_k127_2836778_2 helix_turn_helix, Lux Regulon - - - 0.0000161 54.0
HKD1_k127_2840136_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.031e-320 987.0
HKD1_k127_2840136_1 Male sterility protein - - - 1.892e-309 960.0
HKD1_k127_2840136_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 578.0
HKD1_k127_2840136_11 5'-nucleotidase, C-terminal domain K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 492.0
HKD1_k127_2840136_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 471.0
HKD1_k127_2840136_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 467.0
HKD1_k127_2840136_14 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 443.0
HKD1_k127_2840136_15 esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 433.0
HKD1_k127_2840136_16 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 421.0
HKD1_k127_2840136_17 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 394.0
HKD1_k127_2840136_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 389.0
HKD1_k127_2840136_19 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 370.0
HKD1_k127_2840136_2 Belongs to the malate synthase family K01638 - 2.3.3.9 9.045e-294 907.0
HKD1_k127_2840136_20 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 368.0
HKD1_k127_2840136_21 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 342.0
HKD1_k127_2840136_22 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 316.0
HKD1_k127_2840136_23 Protein of unknown function (DUF2863) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 310.0
HKD1_k127_2840136_24 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 313.0
HKD1_k127_2840136_25 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 290.0
HKD1_k127_2840136_26 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 293.0
HKD1_k127_2840136_27 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001782 273.0
HKD1_k127_2840136_28 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000001083 239.0
HKD1_k127_2840136_29 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000003566 229.0
HKD1_k127_2840136_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.111e-281 876.0
HKD1_k127_2840136_30 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000004449 226.0
HKD1_k127_2840136_31 - - - - 0.000000000000000000000000000000000000000000000000000006557 198.0
HKD1_k127_2840136_32 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000151 200.0
HKD1_k127_2840136_33 Phasin protein - - - 0.0000000000000000000000000000000000000000702 160.0
HKD1_k127_2840136_34 PGAP1-like protein - - - 0.0000000000000000000000000000000000000008447 164.0
HKD1_k127_2840136_35 PFAM poly granule associated family protein - - - 0.0000000000000000000000000000000000001486 146.0
HKD1_k127_2840136_36 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000000004172 136.0
HKD1_k127_2840136_37 PFAM RDD domain containing protein - - - 0.000000000000000000000000002512 118.0
HKD1_k127_2840136_38 Protein of unknown function (DUF3106) - - - 0.0000000000000000000009013 105.0
HKD1_k127_2840136_39 Protein of unknown function (DUF3619) - - - 0.0000000000000002616 90.0
HKD1_k127_2840136_4 Isocitrate lyase K01637 - 4.1.3.1 1.794e-255 790.0
HKD1_k127_2840136_40 - - - - 0.0000000007791 61.0
HKD1_k127_2840136_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.23e-246 777.0
HKD1_k127_2840136_6 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 1.99e-224 709.0
HKD1_k127_2840136_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 2.267e-214 681.0
HKD1_k127_2840136_8 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 4.432e-210 689.0
HKD1_k127_2840136_9 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 603.0
HKD1_k127_2852230_0 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 445.0
HKD1_k127_2852230_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
HKD1_k127_2852230_2 radical SAM domain protein - - - 0.0000000000000000001741 94.0
HKD1_k127_2852230_3 radical SAM domain protein - - - 0.00000000689 61.0
HKD1_k127_2876352_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 429.0
HKD1_k127_2876352_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 342.0
HKD1_k127_2876352_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000002378 166.0
HKD1_k127_2932879_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 445.0
HKD1_k127_2932879_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 413.0
HKD1_k127_2932879_2 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000134 284.0
HKD1_k127_2932879_3 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.0000000000000000000000000000000002291 138.0
HKD1_k127_299638_0 oxidoreductase activity - - - 0.0 1056.0
HKD1_k127_299638_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1021.0
HKD1_k127_299638_10 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000006404 209.0
HKD1_k127_299638_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000133 158.0
HKD1_k127_299638_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.779e-302 941.0
HKD1_k127_299638_3 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 4.633e-240 751.0
HKD1_k127_299638_4 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 587.0
HKD1_k127_299638_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 585.0
HKD1_k127_299638_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 550.0
HKD1_k127_299638_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 297.0
HKD1_k127_299638_8 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000009552 232.0
HKD1_k127_299638_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000379 220.0
HKD1_k127_3002745_0 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
HKD1_k127_3002745_1 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000103 257.0
HKD1_k127_3002745_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000101 203.0
HKD1_k127_3002745_3 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000007584 184.0
HKD1_k127_3002745_4 Radical SAM superfamily K06871 - - 0.000000000000000000000000000000000000000000000003782 175.0
HKD1_k127_3002745_5 PFAM phosphate acetyl butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000002319 144.0
HKD1_k127_3012514_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.938e-219 697.0
HKD1_k127_3012514_1 Transposase - - - 2.011e-194 616.0
HKD1_k127_3012514_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 483.0
HKD1_k127_3012514_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 421.0
HKD1_k127_3012514_4 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
HKD1_k127_3074007_0 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 412.0
HKD1_k127_3074007_1 Aspartate alanine antiporter family protein 1 K07085 - - 0.0000003779 53.0
HKD1_k127_3095977_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 601.0
HKD1_k127_3106023_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 456.0
HKD1_k127_3106023_1 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002794 270.0
HKD1_k127_3106023_2 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000006281 167.0
HKD1_k127_3106023_3 Belongs to the bacterial solute-binding protein 9 family K02077,K09815 - - 0.000000000000000000000000000000000000000003742 158.0
HKD1_k127_3147554_0 PFAM AMP-dependent synthetase and ligase K00666 - - 4.824e-266 830.0
HKD1_k127_3147554_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.053e-248 787.0
HKD1_k127_3147554_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 416.0
HKD1_k127_3147554_11 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 399.0
HKD1_k127_3147554_12 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 343.0
HKD1_k127_3147554_13 TIGRFAM maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 301.0
HKD1_k127_3147554_14 lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001873 272.0
HKD1_k127_3147554_15 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002686 253.0
HKD1_k127_3147554_16 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000003153 183.0
HKD1_k127_3147554_17 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000008015 170.0
HKD1_k127_3147554_18 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000007259 89.0
HKD1_k127_3147554_2 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 550.0
HKD1_k127_3147554_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 548.0
HKD1_k127_3147554_4 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 550.0
HKD1_k127_3147554_5 ABC-type Fe3 transport system, permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 529.0
HKD1_k127_3147554_6 Aminotransferase class-III K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 505.0
HKD1_k127_3147554_7 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 490.0
HKD1_k127_3147554_8 Deacetylases including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 424.0
HKD1_k127_3147554_9 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 419.0
HKD1_k127_3167729_0 Sulfatase K01130 - 3.1.6.1 0.0 1513.0
HKD1_k127_3167729_1 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1157.0
HKD1_k127_3167729_10 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 558.0
HKD1_k127_3167729_11 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 552.0
HKD1_k127_3167729_12 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 522.0
HKD1_k127_3167729_13 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 477.0
HKD1_k127_3167729_14 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 467.0
HKD1_k127_3167729_15 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 448.0
HKD1_k127_3167729_16 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 438.0
HKD1_k127_3167729_17 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 397.0
HKD1_k127_3167729_18 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 376.0
HKD1_k127_3167729_19 Twin-arginine translocation pathway signal sequence - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 384.0
HKD1_k127_3167729_2 helicase superfamily c-terminal domain K03724 - - 0.0 1064.0
HKD1_k127_3167729_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 374.0
HKD1_k127_3167729_21 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 353.0
HKD1_k127_3167729_22 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 347.0
HKD1_k127_3167729_23 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 334.0
HKD1_k127_3167729_24 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 311.0
HKD1_k127_3167729_25 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 310.0
HKD1_k127_3167729_26 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000519 284.0
HKD1_k127_3167729_27 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
HKD1_k127_3167729_28 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 267.0
HKD1_k127_3167729_29 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001229 258.0
HKD1_k127_3167729_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.862e-317 990.0
HKD1_k127_3167729_30 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002229 236.0
HKD1_k127_3167729_31 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001751 228.0
HKD1_k127_3167729_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001902 230.0
HKD1_k127_3167729_33 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000003468 215.0
HKD1_k127_3167729_34 Outer membrane lipoprotein K06077 - - 0.00000000000000000000000000000000000000000000000000000000004123 209.0
HKD1_k127_3167729_35 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000000001057 203.0
HKD1_k127_3167729_36 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000007441 198.0
HKD1_k127_3167729_37 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000007289 197.0
HKD1_k127_3167729_38 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000001282 186.0
HKD1_k127_3167729_39 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.0000000000000000000000000000000000000000000000434 184.0
HKD1_k127_3167729_4 regulation of DNA-templated transcription, elongation - - - 1.641e-292 921.0
HKD1_k127_3167729_40 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000314 151.0
HKD1_k127_3167729_41 SWIB/MDM2 domain K03169 - 5.99.1.2 0.000000000000000000000000000000000001803 141.0
HKD1_k127_3167729_42 - - - - 0.00000000000000000000000000000007639 127.0
HKD1_k127_3167729_43 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000483 123.0
HKD1_k127_3167729_45 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000008753 119.0
HKD1_k127_3167729_46 - - - - 0.000000000000000000000000001857 113.0
HKD1_k127_3167729_47 - - - - 0.00000000000000000000000003634 112.0
HKD1_k127_3167729_48 - - - - 0.0000000000000002709 90.0
HKD1_k127_3167729_49 OmpA-like transmembrane domain K03286 - - 0.00000000000001387 82.0
HKD1_k127_3167729_5 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 7.568e-238 742.0
HKD1_k127_3167729_51 - - - - 0.0000000000003855 73.0
HKD1_k127_3167729_52 - - - - 0.00000000001075 78.0
HKD1_k127_3167729_53 Alpha/beta hydrolase family - - - 0.000000001887 70.0
HKD1_k127_3167729_54 CYTH - - - 0.00000294 52.0
HKD1_k127_3167729_6 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 1.722e-228 719.0
HKD1_k127_3167729_7 Aldehyde dehydrogenase family - - - 1.389e-209 662.0
HKD1_k127_3167729_8 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 599.0
HKD1_k127_3167729_9 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 561.0
HKD1_k127_3173785_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 3.826e-297 925.0
HKD1_k127_3173785_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 6.039e-280 866.0
HKD1_k127_3173785_10 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 572.0
HKD1_k127_3173785_11 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 549.0
HKD1_k127_3173785_12 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 529.0
HKD1_k127_3173785_13 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 516.0
HKD1_k127_3173785_14 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 527.0
HKD1_k127_3173785_15 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 514.0
HKD1_k127_3173785_16 aldo keto reductase K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 499.0
HKD1_k127_3173785_17 Phosphoribulokinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 496.0
HKD1_k127_3173785_18 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 498.0
HKD1_k127_3173785_19 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 460.0
HKD1_k127_3173785_2 synthetase K01907 - 6.2.1.16 5.989e-275 878.0
HKD1_k127_3173785_20 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 445.0
HKD1_k127_3173785_21 LysR substrate binding domain K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 443.0
HKD1_k127_3173785_22 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 399.0
HKD1_k127_3173785_23 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 386.0
HKD1_k127_3173785_24 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 374.0
HKD1_k127_3173785_25 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 365.0
HKD1_k127_3173785_26 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 339.0
HKD1_k127_3173785_27 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 324.0
HKD1_k127_3173785_28 ABC transporter, ATP-binding protein K01996,K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 315.0
HKD1_k127_3173785_29 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 332.0
HKD1_k127_3173785_3 Rieske-like [2Fe-2S] domain - - - 2.232e-235 737.0
HKD1_k127_3173785_30 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 303.0
HKD1_k127_3173785_31 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 297.0
HKD1_k127_3173785_32 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes K21784 GO:0003674,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0048037,GO:0070279,GO:0070280,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 297.0
HKD1_k127_3173785_33 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004871 283.0
HKD1_k127_3173785_34 Chromate resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000019 281.0
HKD1_k127_3173785_35 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000164 266.0
HKD1_k127_3173785_36 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 261.0
HKD1_k127_3173785_37 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007304 253.0
HKD1_k127_3173785_38 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000008292 256.0
HKD1_k127_3173785_39 Dienelactone hydrolase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001821 253.0
HKD1_k127_3173785_4 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 1.428e-224 704.0
HKD1_k127_3173785_40 HlyD family secretion protein K13408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009072 255.0
HKD1_k127_3173785_41 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000001826 242.0
HKD1_k127_3173785_42 Sensors of blue-light using FAD - - - 0.000000000000000000000000000000000000000000000000000000000000000004659 228.0
HKD1_k127_3173785_43 Transcriptional regulator K21747 - - 0.000000000000000000000000000000000000000000000000000000000002289 227.0
HKD1_k127_3173785_44 PFAM ribulose bisphosphate carboxylase small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000001724 218.0
HKD1_k127_3173785_45 Nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000000000000002308 172.0
HKD1_k127_3173785_46 tetR family - - - 0.00000000000000000000000000000000000000000000403 171.0
HKD1_k127_3173785_47 - - - - 0.000000000000000000000000000000000000000000009161 170.0
HKD1_k127_3173785_48 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000734 167.0
HKD1_k127_3173785_49 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000004808 158.0
HKD1_k127_3173785_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 1.634e-220 692.0
HKD1_k127_3173785_50 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000008309 162.0
HKD1_k127_3173785_51 Acyl dehydratase - - - 0.0000000000000000000000000000000000000005001 155.0
HKD1_k127_3173785_52 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000013 168.0
HKD1_k127_3173785_53 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000001847 161.0
HKD1_k127_3173785_54 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000004616 153.0
HKD1_k127_3173785_55 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.000000000000000000000000000000000000588 154.0
HKD1_k127_3173785_56 Glycine-zipper domain - - - 0.0000000000000000000000000000000000006007 149.0
HKD1_k127_3173785_57 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000004262 142.0
HKD1_k127_3173785_58 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000001162 145.0
HKD1_k127_3173785_59 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000004447 130.0
HKD1_k127_3173785_6 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 9.551e-201 635.0
HKD1_k127_3173785_60 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000001316 116.0
HKD1_k127_3173785_61 Thiol-disulfide isomerase K00384 - 1.8.1.9 0.0000000000000000000001787 103.0
HKD1_k127_3173785_62 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000002052 111.0
HKD1_k127_3173785_63 - - - - 0.000000000000000000003297 96.0
HKD1_k127_3173785_64 Protein of unknown function (DUF4236) - - - 0.00000000000000000003673 103.0
HKD1_k127_3173785_65 - - - - 0.000000000000000001138 93.0
HKD1_k127_3173785_66 - - - - 0.0000000000000001163 84.0
HKD1_k127_3173785_67 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000002362 78.0
HKD1_k127_3173785_68 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000394 79.0
HKD1_k127_3173785_69 DMT(Drug metabolite transporter) superfamily permease - - - 0.000000007846 63.0
HKD1_k127_3173785_7 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 3.076e-200 640.0
HKD1_k127_3173785_70 Cysteine-rich CWC - - - 0.00000001294 60.0
HKD1_k127_3173785_8 Peptidase C39 family K13409 - - 3.102e-198 638.0
HKD1_k127_3173785_9 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 583.0
HKD1_k127_3175364_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 492.0
HKD1_k127_3175364_1 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 349.0
HKD1_k127_3175364_2 Cytochrome c K17223 - - 0.000000000000000000001472 102.0
HKD1_k127_3175364_3 alpha beta - - - 0.000000005076 68.0
HKD1_k127_3245430_0 ABC transporter K06020 - 3.6.3.25 1.594e-300 928.0
HKD1_k127_3245430_1 promotes GTP-dependent translocation of the ribosome during translation K02355 - - 4.233e-235 738.0
HKD1_k127_3245430_2 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 491.0
HKD1_k127_3245430_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 398.0
HKD1_k127_3245430_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 327.0
HKD1_k127_3245430_5 Psort location CytoplasmicMembrane, score 9.46 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009796 264.0
HKD1_k127_3245430_6 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000003176 103.0
HKD1_k127_3276564_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.569e-286 917.0
HKD1_k127_3276564_1 Protein of unknown function - - - 6.962e-240 792.0
HKD1_k127_3276564_10 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 448.0
HKD1_k127_3276564_11 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 436.0
HKD1_k127_3276564_12 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 438.0
HKD1_k127_3276564_13 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 410.0
HKD1_k127_3276564_14 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 406.0
HKD1_k127_3276564_15 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 363.0
HKD1_k127_3276564_16 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 364.0
HKD1_k127_3276564_17 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 329.0
HKD1_k127_3276564_18 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 314.0
HKD1_k127_3276564_19 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 289.0
HKD1_k127_3276564_2 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 9.161e-228 740.0
HKD1_k127_3276564_20 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000999 289.0
HKD1_k127_3276564_21 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003277 280.0
HKD1_k127_3276564_22 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002568 265.0
HKD1_k127_3276564_23 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000001048 226.0
HKD1_k127_3276564_24 Protein of unknown function (DUF1345) - - - 0.0000000000000000000000000000000000000000000000000000000000009856 217.0
HKD1_k127_3276564_25 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000001389 205.0
HKD1_k127_3276564_26 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000000000000000000000000000000000002977 201.0
HKD1_k127_3276564_27 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000001037 97.0
HKD1_k127_3276564_3 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 5.749e-227 713.0
HKD1_k127_3276564_4 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 3.384e-224 711.0
HKD1_k127_3276564_5 Bacterial extracellular solute-binding protein K02027 - - 9.04e-214 671.0
HKD1_k127_3276564_6 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 597.0
HKD1_k127_3276564_7 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 509.0
HKD1_k127_3276564_8 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 503.0
HKD1_k127_3276564_9 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 484.0
HKD1_k127_3319730_0 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 467.0
HKD1_k127_3319730_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 465.0
HKD1_k127_3319730_2 - - - - 0.0000000000000000000000000000000000000000000000000007832 194.0
HKD1_k127_3319730_3 WYL domain - - - 0.00000000000000000000000000000003291 135.0
HKD1_k127_3319730_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000004612 124.0
HKD1_k127_3323547_0 belongs to the aldehyde dehydrogenase family K00146 - 1.2.1.39 2.672e-223 697.0
HKD1_k127_3323547_1 PFAM Enoyl-CoA hydratase isomerase K18383 - 4.1.2.41,4.2.1.101 0.0000000000000000000000000000000000000000000000000000000002556 204.0
HKD1_k127_3330686_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000009863 223.0
HKD1_k127_3330686_1 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000003215 150.0
HKD1_k127_3330686_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000336 136.0
HKD1_k127_3330686_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000002312 119.0
HKD1_k127_3360367_0 4Fe-4S dicluster domain - - - 7.821e-194 612.0
HKD1_k127_3360367_1 AsmA family K07290 - - 0.00000000000000000000000000000000000000000000000004442 186.0
HKD1_k127_3377852_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1405.0
HKD1_k127_3377852_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.573e-257 800.0
HKD1_k127_3377852_10 Type II transport protein GspH K08084 - - 0.0000000000000002066 87.0
HKD1_k127_3377852_11 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.00000000000001854 81.0
HKD1_k127_3377852_12 type iv pilus assembly protein K02672 - - 0.00000000000005592 83.0
HKD1_k127_3377852_13 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.00000000000008337 79.0
HKD1_k127_3377852_14 Belongs to the ompA family K03286 - - 0.0000000000004103 76.0
HKD1_k127_3377852_15 Pilus assembly protein PilX K02673 - - 0.00006266 55.0
HKD1_k127_3377852_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 519.0
HKD1_k127_3377852_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 512.0
HKD1_k127_3377852_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 498.0
HKD1_k127_3377852_5 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 487.0
HKD1_k127_3377852_6 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 453.0
HKD1_k127_3377852_7 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 419.0
HKD1_k127_3377852_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001017 268.0
HKD1_k127_3377852_9 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001702 264.0
HKD1_k127_3387586_0 Transporter K07003 - - 2.598e-207 656.0
HKD1_k127_3387586_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 596.0
HKD1_k127_3387586_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 323.0
HKD1_k127_3387586_3 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000004394 228.0
HKD1_k127_3395096_0 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000004821 190.0
HKD1_k127_3395096_1 - - - - 0.000000000000000000000000000000000000000000000000006024 190.0
HKD1_k127_3406648_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 322.0
HKD1_k127_3406648_1 Mg2 and Co2 transporter K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 295.0
HKD1_k127_3406648_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000005848 148.0
HKD1_k127_3422807_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 585.0
HKD1_k127_3422807_1 KR domain - - - 0.00000000000000000000000000008536 119.0
HKD1_k127_3449544_0 CHASE2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 465.0
HKD1_k127_3449544_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 415.0
HKD1_k127_3449544_2 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006304 267.0
HKD1_k127_3449544_3 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000152 263.0
HKD1_k127_3449544_4 Domain of unknown function (DUF4136) - - - 0.000000001215 68.0
HKD1_k127_3470853_0 AcrB/AcrD/AcrF family - - - 0.0 1322.0
HKD1_k127_3470853_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1072.0
HKD1_k127_3470853_10 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 331.0
HKD1_k127_3470853_11 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 335.0
HKD1_k127_3470853_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 326.0
HKD1_k127_3470853_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005569 258.0
HKD1_k127_3470853_14 DsrE/DsrF-like family K07235 - - 0.000000000000000000000000000000000000000000000000000000000002272 209.0
HKD1_k127_3470853_15 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000000000000000002207 196.0
HKD1_k127_3470853_16 Belongs to the DsrF TusC family K07236 - - 0.0000000000000000000000000000000000000000000000002161 178.0
HKD1_k127_3470853_17 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000001571 172.0
HKD1_k127_3470853_18 Cas6 Crispr - - - 0.00000000000000000000000000000000000000004499 160.0
HKD1_k127_3470853_19 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000481 153.0
HKD1_k127_3470853_2 Fe-S oxidoreductase K21834 - - 9.245e-283 873.0
HKD1_k127_3470853_20 - - - - 0.0000000000000000000000000000000000000002896 158.0
HKD1_k127_3470853_21 DsrH like protein K07237 - - 0.000000000000000000000000000000002147 131.0
HKD1_k127_3470853_22 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000001395 118.0
HKD1_k127_3470853_23 - - - - 0.000000000000000000000002265 110.0
HKD1_k127_3470853_24 LysR substrate binding domain K18297 - - 0.000000000000000000003311 95.0
HKD1_k127_3470853_25 Sulphur transport K07112 - - 0.000000000000000000005875 96.0
HKD1_k127_3470853_26 - - - - 0.00000000000000000002015 94.0
HKD1_k127_3470853_27 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000003315 85.0
HKD1_k127_3470853_28 Belongs to the HesB IscA family K13628 - - 0.00000000000001662 87.0
HKD1_k127_3470853_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 2.028e-246 766.0
HKD1_k127_3470853_4 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 9.244e-206 662.0
HKD1_k127_3470853_5 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 529.0
HKD1_k127_3470853_6 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 442.0
HKD1_k127_3470853_7 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 417.0
HKD1_k127_3470853_8 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 375.0
HKD1_k127_3470853_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 352.0
HKD1_k127_3471890_0 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 613.0
HKD1_k127_3471890_1 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 583.0
HKD1_k127_3471890_10 redox protein regulator of disulfide bond formation - - - 0.00000000000000000000000000000000007713 141.0
HKD1_k127_3471890_11 - - - - 0.0000000000000000000000000001945 126.0
HKD1_k127_3471890_12 Hydrogenase maturation protease - - - 0.0000000000000000000001998 104.0
HKD1_k127_3471890_13 ThiS family K03154 - - 0.00000000000000000002786 91.0
HKD1_k127_3471890_15 Protein of unknown function (DUF1439) - - - 0.000005968 55.0
HKD1_k127_3471890_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 504.0
HKD1_k127_3471890_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 425.0
HKD1_k127_3471890_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 421.0
HKD1_k127_3471890_5 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 414.0
HKD1_k127_3471890_6 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 342.0
HKD1_k127_3471890_7 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 321.0
HKD1_k127_3471890_8 Coenzyme F420-reducing hydrogenase, gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 287.0
HKD1_k127_3471890_9 Cupin 2, conserved barrel domain protein K00450,K00971,K09988,K11312 - 1.13.11.4,2.7.7.13,5.3.1.15 0.0000000000000000000000000000000000000000000001019 187.0
HKD1_k127_3511760_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000001743 227.0
HKD1_k127_3511760_1 SnoaL-like domain - - - 0.0000000000000000000000002932 112.0
HKD1_k127_3511761_0 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 473.0
HKD1_k127_3511761_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 450.0
HKD1_k127_3511761_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 405.0
HKD1_k127_3511761_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 266.0
HKD1_k127_3544178_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1598.0
HKD1_k127_3544178_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1138.0
HKD1_k127_3544178_10 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004659 268.0
HKD1_k127_3544178_11 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000007628 181.0
HKD1_k127_3544178_12 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000003093 165.0
HKD1_k127_3544178_13 BON domain - - - 0.000000000000000000000000000000000001793 151.0
HKD1_k127_3544178_14 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000002467 146.0
HKD1_k127_3544178_15 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000304 124.0
HKD1_k127_3544178_16 PFAM Copper binding periplasmic protein CusF - - - 0.0000000000000000007202 92.0
HKD1_k127_3544178_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 4.406e-210 661.0
HKD1_k127_3544178_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 527.0
HKD1_k127_3544178_4 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 515.0
HKD1_k127_3544178_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 505.0
HKD1_k127_3544178_6 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 350.0
HKD1_k127_3544178_7 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 352.0
HKD1_k127_3544178_8 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 317.0
HKD1_k127_3544178_9 COG1538 Outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 327.0
HKD1_k127_3562953_0 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 367.0
HKD1_k127_3569563_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1347.0
HKD1_k127_3569563_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1281.0
HKD1_k127_3569563_10 AMP-binding enzyme C-terminal domain K18661 - - 2.268e-218 695.0
HKD1_k127_3569563_11 PFAM extracellular solute-binding protein family 1 K05813 - - 5.642e-218 685.0
HKD1_k127_3569563_12 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.083e-194 643.0
HKD1_k127_3569563_13 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 613.0
HKD1_k127_3569563_14 Pilus retraction K02669,K12203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 590.0
HKD1_k127_3569563_15 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 601.0
HKD1_k127_3569563_16 Type II/IV secretion system protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 582.0
HKD1_k127_3569563_17 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 575.0
HKD1_k127_3569563_18 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 545.0
HKD1_k127_3569563_19 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 557.0
HKD1_k127_3569563_2 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.0 1114.0
HKD1_k127_3569563_20 ATPases associated with a variety of cellular activities K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 489.0
HKD1_k127_3569563_21 Oxidoreductase FAD-binding domain K00523,K18248 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 483.0
HKD1_k127_3569563_22 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 477.0
HKD1_k127_3569563_23 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 455.0
HKD1_k127_3569563_24 Binding-protein-dependent transport system inner membrane component K02025,K05814,K10118,K17242,K17245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 453.0
HKD1_k127_3569563_25 D-amino acid K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 460.0
HKD1_k127_3569563_26 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 475.0
HKD1_k127_3569563_27 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 458.0
HKD1_k127_3569563_28 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 450.0
HKD1_k127_3569563_29 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 452.0
HKD1_k127_3569563_3 helicase K03657 - 3.6.4.12 0.0 1027.0
HKD1_k127_3569563_30 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 434.0
HKD1_k127_3569563_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 428.0
HKD1_k127_3569563_32 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 398.0
HKD1_k127_3569563_33 THUMP domain K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 400.0
HKD1_k127_3569563_34 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 396.0
HKD1_k127_3569563_35 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 394.0
HKD1_k127_3569563_36 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 380.0
HKD1_k127_3569563_37 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 371.0
HKD1_k127_3569563_38 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 360.0
HKD1_k127_3569563_39 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 361.0
HKD1_k127_3569563_4 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 7.106e-310 961.0
HKD1_k127_3569563_40 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 351.0
HKD1_k127_3569563_41 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 348.0
HKD1_k127_3569563_42 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 348.0
HKD1_k127_3569563_43 receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 347.0
HKD1_k127_3569563_44 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 325.0
HKD1_k127_3569563_45 Catalase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 324.0
HKD1_k127_3569563_46 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 319.0
HKD1_k127_3569563_47 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 328.0
HKD1_k127_3569563_48 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 308.0
HKD1_k127_3569563_49 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 317.0
HKD1_k127_3569563_5 Proton-conducting membrane transporter - - - 2.068e-308 957.0
HKD1_k127_3569563_50 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001377 276.0
HKD1_k127_3569563_51 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001875 272.0
HKD1_k127_3569563_52 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001892 273.0
HKD1_k127_3569563_53 Biopolymer transport K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
HKD1_k127_3569563_54 Periplasmic binding protein K02016,K06858 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000473 273.0
HKD1_k127_3569563_55 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001142 268.0
HKD1_k127_3569563_56 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001998 278.0
HKD1_k127_3569563_57 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000005976 248.0
HKD1_k127_3569563_58 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000002569 248.0
HKD1_k127_3569563_59 COG0671 Membrane-associated phospholipid phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005091 254.0
HKD1_k127_3569563_6 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.119e-296 917.0
HKD1_k127_3569563_60 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000002969 242.0
HKD1_k127_3569563_61 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008919 237.0
HKD1_k127_3569563_62 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000001422 222.0
HKD1_k127_3569563_63 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
HKD1_k127_3569563_64 SMART cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000004326 218.0
HKD1_k127_3569563_65 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000001211 197.0
HKD1_k127_3569563_66 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000009898 177.0
HKD1_k127_3569563_67 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000004235 178.0
HKD1_k127_3569563_68 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000007349 160.0
HKD1_k127_3569563_69 Biopolymer transport protein, ExbD K03559 - - 0.00000000000000000000000000000000000001784 151.0
HKD1_k127_3569563_7 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.412e-292 903.0
HKD1_k127_3569563_70 GrpB protein - - - 0.0000000000000000000000000000000000003131 147.0
HKD1_k127_3569563_71 Cytochrome c K08738 - - 0.000000000000000000000000000000000001439 141.0
HKD1_k127_3569563_72 - - - - 0.000000000000000000000000000000000002016 148.0
HKD1_k127_3569563_73 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000063 145.0
HKD1_k127_3569563_74 SmpA / OmlA family - - - 0.0000000000000000000000000003684 120.0
HKD1_k127_3569563_75 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000001314 114.0
HKD1_k127_3569563_76 Cell division protein ZapA K09888 - - 0.000000000000000000002428 100.0
HKD1_k127_3569563_77 Protein of unknown function (DUF4019) - - - 0.000000000000000000003165 102.0
HKD1_k127_3569563_78 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000000006181 90.0
HKD1_k127_3569563_79 Protein of unknown function (DUF3460) - - - 0.000000000000002138 80.0
HKD1_k127_3569563_8 Proton-conducting membrane transporter K12141 - - 3.26e-249 777.0
HKD1_k127_3569563_80 - - - - 0.000000000004961 69.0
HKD1_k127_3569563_81 - - - - 0.000001907 53.0
HKD1_k127_3569563_9 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 8.641e-228 711.0
HKD1_k127_3577198_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 528.0
HKD1_k127_3577198_1 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 319.0
HKD1_k127_3577198_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
HKD1_k127_3577198_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000004735 169.0
HKD1_k127_3739397_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 4.595e-289 893.0
HKD1_k127_3739397_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 373.0
HKD1_k127_3739397_2 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009779 281.0
HKD1_k127_3739397_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000008355 251.0
HKD1_k127_3739397_4 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000004612 246.0
HKD1_k127_3739397_5 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000007951 237.0
HKD1_k127_3739397_6 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000003829 168.0
HKD1_k127_3739397_7 Domain of unknown function (DUF4936) - - - 0.0000009266 59.0
HKD1_k127_3764301_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 8.57e-244 768.0
HKD1_k127_3764301_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 599.0
HKD1_k127_3764301_10 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000003827 132.0
HKD1_k127_3764301_11 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000006739 81.0
HKD1_k127_3764301_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 437.0
HKD1_k127_3764301_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 437.0
HKD1_k127_3764301_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 427.0
HKD1_k127_3764301_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 347.0
HKD1_k127_3764301_6 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004725 275.0
HKD1_k127_3764301_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000007414 226.0
HKD1_k127_3764301_8 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000271 201.0
HKD1_k127_3764301_9 Protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000000009644 190.0
HKD1_k127_3799925_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.927e-244 762.0
HKD1_k127_3799925_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.635e-194 616.0
HKD1_k127_3799925_10 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000001613 131.0
HKD1_k127_3799925_11 Domain of unknown function (DUF4124) - - - 0.0000000000000000000003536 105.0
HKD1_k127_3799925_12 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000009738 87.0
HKD1_k127_3799925_2 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 526.0
HKD1_k127_3799925_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 468.0
HKD1_k127_3799925_4 C-terminal region of band_7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 461.0
HKD1_k127_3799925_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 308.0
HKD1_k127_3799925_6 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 306.0
HKD1_k127_3799925_7 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000002345 223.0
HKD1_k127_3799925_8 Oligoketide cyclase lipid transport protein - - - 0.000000000000000000000000000000000000000000000004435 177.0
HKD1_k127_3799925_9 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000309 169.0
HKD1_k127_3844947_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.462e-318 984.0
HKD1_k127_3844947_1 L-serine dehydratase K01752 - 4.3.1.17 1.03e-218 691.0
HKD1_k127_3844947_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 458.0
HKD1_k127_3844947_3 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000008631 211.0
HKD1_k127_3844947_4 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000306 80.0
HKD1_k127_3897716_0 Domain of unknown function (DUF3479) K03403 - 6.6.1.1 0.0 1825.0
HKD1_k127_3897716_1 Histidine kinase K02487,K06596 - - 0.0 1230.0
HKD1_k127_3897716_10 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 2.33e-215 691.0
HKD1_k127_3897716_11 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 4.14e-203 646.0
HKD1_k127_3897716_12 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 2.352e-202 638.0
HKD1_k127_3897716_13 von Willebrand factor type A domain K03404 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 616.0
HKD1_k127_3897716_14 Major facilitator superfamily K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 604.0
HKD1_k127_3897716_15 oxidoreductase activity, acting on iron-sulfur proteins as donors K04037,K11333 - 1.3.7.14,1.3.7.15,1.3.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 578.0
HKD1_k127_3897716_16 Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 576.0
HKD1_k127_3897716_17 The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis K08929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 558.0
HKD1_k127_3897716_18 phytoene K09845 - 1.3.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 561.0
HKD1_k127_3897716_19 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 549.0
HKD1_k127_3897716_2 B12 binding domain K04034 - 1.21.98.3 2.358e-310 970.0
HKD1_k127_3897716_20 Photosynthetic reaction center L subunit K08928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 535.0
HKD1_k127_3897716_21 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 534.0
HKD1_k127_3897716_22 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 519.0
HKD1_k127_3897716_23 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 532.0
HKD1_k127_3897716_24 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 519.0
HKD1_k127_3897716_25 Light harvesting pigment Major Facilitator Family (MFS) transporter K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 488.0
HKD1_k127_3897716_26 Dehydrogenase K11337 - 1.1.1.396 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 440.0
HKD1_k127_3897716_27 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 421.0
HKD1_k127_3897716_28 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 398.0
HKD1_k127_3897716_29 Dimerisation domain K09846 - 2.1.1.210 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 379.0
HKD1_k127_3897716_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.972e-290 900.0
HKD1_k127_3897716_30 Phytoene squalene synthetase K02291 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 374.0
HKD1_k127_3897716_31 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 357.0
HKD1_k127_3897716_32 Serine aminopeptidase, S33 K06049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 352.0
HKD1_k127_3897716_33 hydroxyneurosporene synthase K09844 - 4.2.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 337.0
HKD1_k127_3897716_34 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 - 2.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 311.0
HKD1_k127_3897716_35 Photosynthetic reaction centre, H-chain N-terminal region K13991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 308.0
HKD1_k127_3897716_36 transcriptional regulator PpsR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 304.0
HKD1_k127_3897716_37 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003749 292.0
HKD1_k127_3897716_38 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006322 271.0
HKD1_k127_3897716_39 Protein of unknown function (DUF3623) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004658 256.0
HKD1_k127_3897716_4 Proto-chlorophyllide reductase 57 kD subunit K11335 - 1.3.7.14,1.3.7.15 5.405e-263 827.0
HKD1_k127_3897716_40 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000005131 234.0
HKD1_k127_3897716_41 PFAM 2-vinyl bacteriochlorophyllide hydratase K11336 - 4.2.1.165 0.00000000000000000000000000000000000000000000000000000000000000002258 228.0
HKD1_k127_3897716_42 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000000000000000000000000003713 222.0
HKD1_k127_3897716_43 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000006949 214.0
HKD1_k127_3897716_44 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000006974 206.0
HKD1_k127_3897716_45 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000000005445 192.0
HKD1_k127_3897716_46 Bacteriochlorophyll 4-vinyl reductase K04036 - - 0.00000000000000000000000000000000000000000000000000001418 200.0
HKD1_k127_3897716_47 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000005547 193.0
HKD1_k127_3897716_48 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000583 168.0
HKD1_k127_3897716_49 Heme oxygenase K21480 - 1.14.15.20 0.00000000000000000000000000000000000000000006525 168.0
HKD1_k127_3897716_5 Nitrogenase component 1 type Oxidoreductase K11334 - 1.3.7.14,1.3.7.15 6.852e-262 816.0
HKD1_k127_3897716_50 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) - - - 0.000000000000000000000000000000000000000004399 167.0
HKD1_k127_3897716_51 B12 binding domain - - - 0.00000000000000000000000000000000000000002941 165.0
HKD1_k127_3897716_52 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000001974 140.0
HKD1_k127_3897716_53 Photosynthetic complex assembly protein - - - 0.0000000000000000000000000000001001 132.0
HKD1_k127_3897716_54 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000003839 120.0
HKD1_k127_3897716_55 Chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000005414 117.0
HKD1_k127_3897716_56 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000001347 104.0
HKD1_k127_3897716_57 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08926 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000004961 87.0
HKD1_k127_3897716_58 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000005235 84.0
HKD1_k127_3897716_59 - - - - 0.000000000000006703 78.0
HKD1_k127_3897716_6 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 1.364e-250 783.0
HKD1_k127_3897716_60 - K08927 - - 0.00000000000002188 75.0
HKD1_k127_3897716_61 PFAM OmpA MotB domain protein - - - 0.0000000007784 72.0
HKD1_k127_3897716_7 Flavin containing amine oxidoreductase - - - 2.839e-244 762.0
HKD1_k127_3897716_8 Bacteriophytochrome (Light-regulated signal transduction histidine kinase) - - - 9.845e-239 759.0
HKD1_k127_3897716_9 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.562e-217 704.0
HKD1_k127_3991879_0 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 301.0
HKD1_k127_3991879_1 Methyltransferase domain - - - 0.000000000000000000000000000000001586 142.0
HKD1_k127_3994911_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1339.0
HKD1_k127_3994911_1 Two component regulator propeller - - - 1.444e-272 859.0
HKD1_k127_3994911_10 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 547.0
HKD1_k127_3994911_11 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 524.0
HKD1_k127_3994911_12 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 500.0
HKD1_k127_3994911_13 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 488.0
HKD1_k127_3994911_14 - K06905 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 477.0
HKD1_k127_3994911_15 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 451.0
HKD1_k127_3994911_16 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 434.0
HKD1_k127_3994911_17 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 419.0
HKD1_k127_3994911_18 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 420.0
HKD1_k127_3994911_19 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 383.0
HKD1_k127_3994911_2 ABC transporter transmembrane region K06147 - - 2.434e-270 843.0
HKD1_k127_3994911_20 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 378.0
HKD1_k127_3994911_21 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 354.0
HKD1_k127_3994911_22 Nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 349.0
HKD1_k127_3994911_23 AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 338.0
HKD1_k127_3994911_24 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 322.0
HKD1_k127_3994911_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 337.0
HKD1_k127_3994911_26 phage tail tape measure protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 327.0
HKD1_k127_3994911_27 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 317.0
HKD1_k127_3994911_28 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 328.0
HKD1_k127_3994911_29 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 300.0
HKD1_k127_3994911_3 COG0474 Cation transport ATPase K01531 - 3.6.3.2 7.679e-262 831.0
HKD1_k127_3994911_30 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005916 282.0
HKD1_k127_3994911_31 domain, Protein K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001545 283.0
HKD1_k127_3994911_32 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001479 260.0
HKD1_k127_3994911_33 PFAM Phage-related baseplate assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006566 245.0
HKD1_k127_3994911_34 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000007617 236.0
HKD1_k127_3994911_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004459 228.0
HKD1_k127_3994911_36 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000005473 215.0
HKD1_k127_3994911_37 - - - - 0.00000000000000000000000000000000000000000000001631 179.0
HKD1_k127_3994911_38 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000000000001318 170.0
HKD1_k127_3994911_39 acetyltransferase - - - 0.000000000000000000000000000000000000005279 153.0
HKD1_k127_3994911_4 homolog of phage Mu protein gp47 - - - 2.842e-252 803.0
HKD1_k127_3994911_40 - - - - 0.00000000000000000000000000000000000003811 145.0
HKD1_k127_3994911_41 - - - - 0.0000000000000000000000000000000000001295 145.0
HKD1_k127_3994911_42 MAPEG family - - - 0.000000000000000000000000000000000004098 141.0
HKD1_k127_3994911_43 LysM domain - - - 0.000000000000000000000000000000555 124.0
HKD1_k127_3994911_44 enzyme binding - - - 0.00000000000000000000000000002985 124.0
HKD1_k127_3994911_45 Methyltransferase domain - - - 0.0000000000000000000000007538 115.0
HKD1_k127_3994911_46 Domain of unknown function (DUF4157) - - - 0.0000000000000000000018 106.0
HKD1_k127_3994911_49 - - - - 0.0000001239 57.0
HKD1_k127_3994911_5 FtsX-like permease family K02004 - - 3.428e-229 753.0
HKD1_k127_3994911_6 protein, phage tail-like region - - - 2.902e-210 693.0
HKD1_k127_3994911_7 Pro-kumamolisin, activation domain K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 610.0
HKD1_k127_3994911_8 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 618.0
HKD1_k127_3994911_9 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 612.0
HKD1_k127_4030811_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 595.0
HKD1_k127_4030811_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 376.0
HKD1_k127_4030811_10 membrane - - - 0.0000000000000000000000000000000000000000000000000000000009047 207.0
HKD1_k127_4030811_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000005513 203.0
HKD1_k127_4030811_12 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000004501 193.0
HKD1_k127_4030811_13 Gram-negative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001246 183.0
HKD1_k127_4030811_14 - - - - 0.0000000000000000000000000000000000000000000804 168.0
HKD1_k127_4030811_15 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000001619 133.0
HKD1_k127_4030811_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 367.0
HKD1_k127_4030811_3 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 309.0
HKD1_k127_4030811_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007717 258.0
HKD1_k127_4030811_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000002476 240.0
HKD1_k127_4030811_6 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000007863 221.0
HKD1_k127_4030811_7 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000183 211.0
HKD1_k127_4030811_8 Phosphoglycerate mutase K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000007799 214.0
HKD1_k127_4030811_9 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000007034 204.0
HKD1_k127_4037257_0 H( )-stimulated, divalent metal cation uptake system - - - 6.814e-194 612.0
HKD1_k127_4037257_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 436.0
HKD1_k127_4037257_2 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 415.0
HKD1_k127_4037257_3 Catalase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 319.0
HKD1_k127_4037257_4 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 295.0
HKD1_k127_4037257_5 HNH nucleases - - - 0.000000000000000000000000000000000000000000000003031 176.0
HKD1_k127_4037257_6 AAA domain - - - 0.000000000000000000000000000000000000000003391 160.0
HKD1_k127_4043200_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.108e-206 650.0
HKD1_k127_4043200_1 phenylacetic acid degradation protein paaN - - - 3.01e-197 621.0
HKD1_k127_4043200_2 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 593.0
HKD1_k127_4043200_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 563.0
HKD1_k127_4043200_4 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 351.0
HKD1_k127_4043200_5 phenylacetic acid degradation protein K02614 - - 0.000000000000000000000000000000000000000000000003327 180.0
HKD1_k127_4057317_0 FAD linked oxidase domain protein - - - 0.0 1994.0
HKD1_k127_4057317_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 374.0
HKD1_k127_4057317_10 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000004364 157.0
HKD1_k127_4057317_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000002599 151.0
HKD1_k127_4057317_12 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000000004846 127.0
HKD1_k127_4057317_13 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000002632 117.0
HKD1_k127_4057317_14 Sporulation related domain - - - 0.0000000000001231 80.0
HKD1_k127_4057317_15 - - - - 0.000000002229 65.0
HKD1_k127_4057317_2 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 357.0
HKD1_k127_4057317_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 295.0
HKD1_k127_4057317_4 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 299.0
HKD1_k127_4057317_5 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 298.0
HKD1_k127_4057317_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 285.0
HKD1_k127_4057317_7 Serine aminopeptidase, S33 K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000299 229.0
HKD1_k127_4057317_8 Ferredoxin - - - 0.0000000000000000000000000000000000000000000001028 169.0
HKD1_k127_4057317_9 HIT domain - - - 0.0000000000000000000000000000000000000000000008968 174.0
HKD1_k127_4082260_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1701.0
HKD1_k127_4082260_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.95e-286 889.0
HKD1_k127_4082260_10 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 469.0
HKD1_k127_4082260_11 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 467.0
HKD1_k127_4082260_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 457.0
HKD1_k127_4082260_13 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 424.0
HKD1_k127_4082260_14 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 426.0
HKD1_k127_4082260_15 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 401.0
HKD1_k127_4082260_16 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 391.0
HKD1_k127_4082260_17 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 400.0
HKD1_k127_4082260_18 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 387.0
HKD1_k127_4082260_19 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 374.0
HKD1_k127_4082260_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.678e-246 765.0
HKD1_k127_4082260_20 Dolichyl-phosphate-mannose-protein mannosyltransferase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 330.0
HKD1_k127_4082260_21 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 291.0
HKD1_k127_4082260_22 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 284.0
HKD1_k127_4082260_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005084 279.0
HKD1_k127_4082260_24 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003673 272.0
HKD1_k127_4082260_25 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 263.0
HKD1_k127_4082260_26 Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000006694 238.0
HKD1_k127_4082260_27 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000001251 224.0
HKD1_k127_4082260_28 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000003795 212.0
HKD1_k127_4082260_29 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000001856 214.0
HKD1_k127_4082260_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.751e-232 722.0
HKD1_k127_4082260_30 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000001534 183.0
HKD1_k127_4082260_31 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000005479 176.0
HKD1_k127_4082260_32 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000001236 155.0
HKD1_k127_4082260_33 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000001078 163.0
HKD1_k127_4082260_34 MAPEG family - - - 0.00000000000000000000000000000000001518 142.0
HKD1_k127_4082260_35 there appears to be two types of ribosomal proteins L31 in bacterial genomes K02909 - - 0.0000000000000000000000000000000009077 135.0
HKD1_k127_4082260_36 CRS1_YhbY K07574 - - 0.00000000000000000000000000005343 123.0
HKD1_k127_4082260_37 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000002714 61.0
HKD1_k127_4082260_38 D-galactarate dehydratase Altronate hydrolase K01708,K16846 - 4.2.1.42,4.4.1.24 0.00001723 55.0
HKD1_k127_4082260_4 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 3.186e-227 747.0
HKD1_k127_4082260_5 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 2.714e-200 629.0
HKD1_k127_4082260_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 592.0
HKD1_k127_4082260_7 Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 556.0
HKD1_k127_4082260_8 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 507.0
HKD1_k127_4082260_9 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 499.0
HKD1_k127_408621_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1019.0
HKD1_k127_408621_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 359.0
HKD1_k127_408621_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 302.0
HKD1_k127_408621_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000001671 168.0
HKD1_k127_408621_4 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000006793 114.0
HKD1_k127_408621_5 Belongs to the UPF0434 family K09791 - - 0.000000000000000000004241 93.0
HKD1_k127_408621_6 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000001749 75.0
HKD1_k127_4090907_0 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001326 285.0
HKD1_k127_4090907_1 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.00000635 55.0
HKD1_k127_4094549_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2519.0
HKD1_k127_4094549_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 9.102e-294 923.0
HKD1_k127_4094549_10 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 466.0
HKD1_k127_4094549_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 451.0
HKD1_k127_4094549_12 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 436.0
HKD1_k127_4094549_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 400.0
HKD1_k127_4094549_14 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 378.0
HKD1_k127_4094549_15 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 341.0
HKD1_k127_4094549_16 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 342.0
HKD1_k127_4094549_17 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 333.0
HKD1_k127_4094549_18 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 344.0
HKD1_k127_4094549_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 328.0
HKD1_k127_4094549_2 Secretin and TonB N terminus short domain K02666 - - 1.308e-242 771.0
HKD1_k127_4094549_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 311.0
HKD1_k127_4094549_21 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 295.0
HKD1_k127_4094549_22 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 280.0
HKD1_k127_4094549_23 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001338 263.0
HKD1_k127_4094549_24 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 256.0
HKD1_k127_4094549_25 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001608 243.0
HKD1_k127_4094549_26 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000001515 242.0
HKD1_k127_4094549_27 PFAM cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000002452 244.0
HKD1_k127_4094549_28 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000002173 234.0
HKD1_k127_4094549_29 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000006408 228.0
HKD1_k127_4094549_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.409e-236 738.0
HKD1_k127_4094549_30 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000002276 225.0
HKD1_k127_4094549_31 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000001048 236.0
HKD1_k127_4094549_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000007374 218.0
HKD1_k127_4094549_33 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000005871 212.0
HKD1_k127_4094549_34 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000006122 199.0
HKD1_k127_4094549_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000003518 196.0
HKD1_k127_4094549_36 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000001083 194.0
HKD1_k127_4094549_37 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000005168 198.0
HKD1_k127_4094549_38 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000001254 198.0
HKD1_k127_4094549_39 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000001499 193.0
HKD1_k127_4094549_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 550.0
HKD1_k127_4094549_40 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000000007847 195.0
HKD1_k127_4094549_41 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000223 186.0
HKD1_k127_4094549_42 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000454 176.0
HKD1_k127_4094549_43 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000003604 173.0
HKD1_k127_4094549_44 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000001762 151.0
HKD1_k127_4094549_45 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000000909 149.0
HKD1_k127_4094549_46 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000003491 135.0
HKD1_k127_4094549_47 heat shock protein K04762 - - 0.0000000000000000000000000000000005885 140.0
HKD1_k127_4094549_48 tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000966 144.0
HKD1_k127_4094549_49 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000002383 133.0
HKD1_k127_4094549_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 548.0
HKD1_k127_4094549_50 Belongs to the frataxin family K06202 - - 0.000000000000000000000000000000004862 131.0
HKD1_k127_4094549_51 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000000009851 94.0
HKD1_k127_4094549_52 Ribosomal L29 protein K02904 - - 0.00000000000000006382 83.0
HKD1_k127_4094549_53 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001413 79.0
HKD1_k127_4094549_54 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000002951 72.0
HKD1_k127_4094549_55 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 0.000002304 49.0
HKD1_k127_4094549_56 protein conserved in bacteria K09914 - - 0.0003578 51.0
HKD1_k127_4094549_6 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 539.0
HKD1_k127_4094549_7 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 538.0
HKD1_k127_4094549_8 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 523.0
HKD1_k127_4094549_9 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 473.0
HKD1_k127_4115086_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000001367 177.0
HKD1_k127_4115086_1 LytTr DNA-binding domain - - - 0.000000000000000000000000000001222 125.0
HKD1_k127_4125710_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1384.0
HKD1_k127_4125710_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.474e-299 924.0
HKD1_k127_4125710_10 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 485.0
HKD1_k127_4125710_11 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 502.0
HKD1_k127_4125710_12 surface antigen (D15) K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 458.0
HKD1_k127_4125710_13 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 443.0
HKD1_k127_4125710_14 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 414.0
HKD1_k127_4125710_15 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 390.0
HKD1_k127_4125710_16 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 386.0
HKD1_k127_4125710_17 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 392.0
HKD1_k127_4125710_18 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
HKD1_k127_4125710_19 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
HKD1_k127_4125710_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 2.252e-277 862.0
HKD1_k127_4125710_20 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 305.0
HKD1_k127_4125710_21 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 301.0
HKD1_k127_4125710_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 298.0
HKD1_k127_4125710_23 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005374 263.0
HKD1_k127_4125710_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001324 230.0
HKD1_k127_4125710_25 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000003675 228.0
HKD1_k127_4125710_26 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000001532 199.0
HKD1_k127_4125710_27 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000001842 183.0
HKD1_k127_4125710_28 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000001207 164.0
HKD1_k127_4125710_29 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000001815 159.0
HKD1_k127_4125710_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.325e-237 739.0
HKD1_k127_4125710_30 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000002179 158.0
HKD1_k127_4125710_31 Universal stress protein - - - 0.0000000000000000000000000000000000000001224 155.0
HKD1_k127_4125710_32 Universal stress protein - - - 0.00000000000000000000000000000007581 130.0
HKD1_k127_4125710_33 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000008436 106.0
HKD1_k127_4125710_34 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000008093 104.0
HKD1_k127_4125710_35 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0008452,GO:0008664,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0042578,GO:0140098 3.1.4.58 0.0000000000000001338 89.0
HKD1_k127_4125710_4 LUD domain K18929 - - 2.01e-224 711.0
HKD1_k127_4125710_5 Aminotransferase K14261 - - 1.857e-223 700.0
HKD1_k127_4125710_6 homoserine dehydrogenase K00003 - 1.1.1.3 5.018e-200 633.0
HKD1_k127_4125710_7 Threonine synthase N terminus K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 616.0
HKD1_k127_4125710_8 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 508.0
HKD1_k127_4125710_9 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 495.0
HKD1_k127_4141461_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 3.546e-255 807.0
HKD1_k127_4141461_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.777e-221 696.0
HKD1_k127_4141461_10 TRAP transporter solute receptor TAXI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 336.0
HKD1_k127_4141461_11 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 308.0
HKD1_k127_4141461_12 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 294.0
HKD1_k127_4141461_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005594 294.0
HKD1_k127_4141461_14 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008773 276.0
HKD1_k127_4141461_15 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001311 281.0
HKD1_k127_4141461_16 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 258.0
HKD1_k127_4141461_17 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004142 268.0
HKD1_k127_4141461_18 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000126 241.0
HKD1_k127_4141461_19 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000002549 232.0
HKD1_k127_4141461_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.114e-206 654.0
HKD1_k127_4141461_20 PFAM transport-associated - - - 0.000000000000000000000000000000000000000000000004428 182.0
HKD1_k127_4141461_21 - - - - 0.00000000000000000000000000000000000000004884 163.0
HKD1_k127_4141461_22 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000002052 163.0
HKD1_k127_4141461_23 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.00000000000000000000000000000000001032 145.0
HKD1_k127_4141461_24 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000003848 117.0
HKD1_k127_4141461_25 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000001301 119.0
HKD1_k127_4141461_26 Peptidase family M48 - - - 0.000000000000000000000001357 107.0
HKD1_k127_4141461_27 Las17-binding protein actin regulator - - - 0.00000000000000000000001419 108.0
HKD1_k127_4141461_28 - - - - 0.0000000000000000001034 100.0
HKD1_k127_4141461_29 TIGRFAM phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000009873 82.0
HKD1_k127_4141461_3 Cell shape determining protein, MreB Mrl family K03569 - - 5.139e-201 631.0
HKD1_k127_4141461_4 Major facilitator superfamily K08218 - - 2.885e-197 628.0
HKD1_k127_4141461_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 608.0
HKD1_k127_4141461_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 575.0
HKD1_k127_4141461_7 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 565.0
HKD1_k127_4141461_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 474.0
HKD1_k127_4141461_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 378.0
HKD1_k127_4200048_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 602.0
HKD1_k127_4200048_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 531.0
HKD1_k127_4200048_10 VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000004824 228.0
HKD1_k127_4200048_11 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000002495 139.0
HKD1_k127_4200048_12 Acyl-ACP thioesterase - - - 0.0000000000000000000000000000000001087 138.0
HKD1_k127_4200048_13 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000003399 127.0
HKD1_k127_4200048_14 Belongs to the BolA IbaG family - - - 0.000000000000000000000000001936 124.0
HKD1_k127_4200048_15 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000004951 91.0
HKD1_k127_4200048_16 STAS domain K07122 - - 0.00000000005845 66.0
HKD1_k127_4200048_17 Outer membrane lipoprotein K06077 - - 0.000000002987 63.0
HKD1_k127_4200048_18 Periplasmic component of the Tol biopolymer transport system - - - 0.000001365 58.0
HKD1_k127_4200048_19 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0002551 49.0
HKD1_k127_4200048_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 411.0
HKD1_k127_4200048_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 400.0
HKD1_k127_4200048_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 377.0
HKD1_k127_4200048_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 377.0
HKD1_k127_4200048_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 327.0
HKD1_k127_4200048_7 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000008691 243.0
HKD1_k127_4200048_8 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000006188 231.0
HKD1_k127_4200048_9 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000007305 226.0
HKD1_k127_4205868_0 Glycosyl hydrolases family 15 - - - 2.291e-219 698.0
HKD1_k127_4205868_1 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 5.789e-205 663.0
HKD1_k127_4205868_2 Chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 447.0
HKD1_k127_4205868_3 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009995 250.0
HKD1_k127_4205868_4 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000003609 194.0
HKD1_k127_4205868_5 E1-E2 ATPase K01535 - 3.6.3.6 0.00000000000000000000000000000216 123.0
HKD1_k127_4214595_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1141.0
HKD1_k127_4214595_1 GTP-binding protein K06207 - - 0.0 1009.0
HKD1_k127_4214595_10 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001405 284.0
HKD1_k127_4214595_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000887 281.0
HKD1_k127_4214595_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000171 292.0
HKD1_k127_4214595_13 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003552 270.0
HKD1_k127_4214595_14 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007742 234.0
HKD1_k127_4214595_15 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
HKD1_k127_4214595_16 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000003324 214.0
HKD1_k127_4214595_17 - - - - 0.000000000000000000000000000000000000000001489 171.0
HKD1_k127_4214595_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000009391 168.0
HKD1_k127_4214595_19 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000004083 152.0
HKD1_k127_4214595_2 o-acetylhomoserine K01740 - 2.5.1.49 4.725e-226 712.0
HKD1_k127_4214595_20 HlyD membrane-fusion protein of T1SS K02022,K11003 - - 0.00000000000000000000000000000001141 136.0
HKD1_k127_4214595_21 membrane - - - 0.0000000000000000000000023 106.0
HKD1_k127_4214595_22 Protein of unknown function (DUF2788) - - - 0.000000000000000000001687 106.0
HKD1_k127_4214595_23 cyclic nucleotide binding K10914 - - 0.00000000000000000004038 96.0
HKD1_k127_4214595_24 Transposase IS200 like K07491 - - 0.000007168 48.0
HKD1_k127_4214595_3 Ammonium transporter K03320,K06580 - - 2.965e-220 687.0
HKD1_k127_4214595_4 Participates in both transcription termination and antitermination K02600 - - 5.716e-215 678.0
HKD1_k127_4214595_5 PFAM FAD binding domain, FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 599.0
HKD1_k127_4214595_6 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 437.0
HKD1_k127_4214595_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 434.0
HKD1_k127_4214595_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 332.0
HKD1_k127_4214595_9 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 302.0
HKD1_k127_4219338_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1555.0
HKD1_k127_4219338_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.01e-319 989.0
HKD1_k127_4219338_10 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 596.0
HKD1_k127_4219338_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 571.0
HKD1_k127_4219338_12 PFAM AFG1-family ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 518.0
HKD1_k127_4219338_13 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 459.0
HKD1_k127_4219338_14 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 437.0
HKD1_k127_4219338_15 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 351.0
HKD1_k127_4219338_16 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 349.0
HKD1_k127_4219338_17 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 321.0
HKD1_k127_4219338_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006597 279.0
HKD1_k127_4219338_19 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000004937 248.0
HKD1_k127_4219338_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.863e-304 949.0
HKD1_k127_4219338_20 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000101 231.0
HKD1_k127_4219338_21 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000003397 218.0
HKD1_k127_4219338_22 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000002908 215.0
HKD1_k127_4219338_23 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000004064 102.0
HKD1_k127_4219338_24 PspC domain - - - 0.00000000000000000001365 106.0
HKD1_k127_4219338_25 Protein of unknown function (DUF465) - - - 0.00000000000000006739 81.0
HKD1_k127_4219338_27 electron transfer activity K03737,K05337 - 1.2.7.1 0.0007277 53.0
HKD1_k127_4219338_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.021e-250 779.0
HKD1_k127_4219338_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 4.041e-248 773.0
HKD1_k127_4219338_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.052e-232 729.0
HKD1_k127_4219338_6 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 9.828e-224 710.0
HKD1_k127_4219338_7 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.935e-214 683.0
HKD1_k127_4219338_8 helicase K03722 - 3.6.4.12 1.276e-195 632.0
HKD1_k127_4219338_9 Belongs to the thiolase family K00626 - 2.3.1.9 7.913e-194 610.0
HKD1_k127_4261372_0 molybdopterin cofactor binding K08352 - 1.8.5.5 4.774e-313 973.0
HKD1_k127_4261372_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 531.0
HKD1_k127_4261372_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 331.0
HKD1_k127_4261372_11 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 312.0
HKD1_k127_4261372_12 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 320.0
HKD1_k127_4261372_13 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 290.0
HKD1_k127_4261372_14 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000004412 241.0
HKD1_k127_4261372_15 - K07112 - - 0.0000000000000000000000000000000000000000000004474 173.0
HKD1_k127_4261372_16 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.00000000000000000000000000000000000000000008608 169.0
HKD1_k127_4261372_17 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000002082 158.0
HKD1_k127_4261372_18 Transglycosylase associated protein - - - 0.0000000000000000000000000000000000006332 141.0
HKD1_k127_4261372_19 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000003462 151.0
HKD1_k127_4261372_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 511.0
HKD1_k127_4261372_20 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000476 140.0
HKD1_k127_4261372_21 - - - - 0.0000000000000000002045 97.0
HKD1_k127_4261372_22 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000001869 81.0
HKD1_k127_4261372_23 - - - - 0.000000000000001636 85.0
HKD1_k127_4261372_24 COG4235 Cytochrome c biogenesis factor K02200 - - 0.000000000000004009 84.0
HKD1_k127_4261372_26 Protein of unknown function (DUF4255) - - - 0.000001192 57.0
HKD1_k127_4261372_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
HKD1_k127_4261372_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 520.0
HKD1_k127_4261372_5 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 452.0
HKD1_k127_4261372_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 437.0
HKD1_k127_4261372_7 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 402.0
HKD1_k127_4261372_8 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 387.0
HKD1_k127_4261372_9 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 338.0
HKD1_k127_4277569_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 5.839e-258 818.0
HKD1_k127_4277569_1 alcohol dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 426.0
HKD1_k127_4277569_2 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005099 265.0
HKD1_k127_4277569_3 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002202 258.0
HKD1_k127_4277569_4 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000001808 221.0
HKD1_k127_4277569_5 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000001225 210.0
HKD1_k127_4314454_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.907e-222 699.0
HKD1_k127_4314454_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.456e-205 660.0
HKD1_k127_4314454_10 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
HKD1_k127_4314454_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 355.0
HKD1_k127_4314454_12 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000009308 207.0
HKD1_k127_4314454_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000004265 192.0
HKD1_k127_4314454_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0008714 46.0
HKD1_k127_4314454_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 9.343e-205 649.0
HKD1_k127_4314454_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 4.987e-198 621.0
HKD1_k127_4314454_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 575.0
HKD1_k127_4314454_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 566.0
HKD1_k127_4314454_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 563.0
HKD1_k127_4314454_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 526.0
HKD1_k127_4314454_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 439.0
HKD1_k127_4314454_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 418.0
HKD1_k127_4330905_0 Efflux pump membrane transporter K03296,K18138 - - 1.5e-323 1012.0
HKD1_k127_4330905_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000004404 105.0
HKD1_k127_4363729_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 1.131e-271 845.0
HKD1_k127_4363729_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 1.909e-209 666.0
HKD1_k127_4363729_2 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 521.0
HKD1_k127_4363729_3 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 511.0
HKD1_k127_4363729_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 413.0
HKD1_k127_4363729_5 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 364.0
HKD1_k127_4363729_6 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 333.0
HKD1_k127_4363729_7 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 321.0
HKD1_k127_4367647_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 391.0
HKD1_k127_4367647_1 Histidine kinase - - - 0.0005393 53.0
HKD1_k127_4367647_2 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0005393 53.0
HKD1_k127_438542_0 permease K03303 - - 0.0 1017.0
HKD1_k127_438542_1 Highly conserved protein containing a thioredoxin domain K06888 - - 6.472e-226 721.0
HKD1_k127_438542_2 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005286 268.0
HKD1_k127_438542_3 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000341 267.0
HKD1_k127_438542_4 response regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000005222 244.0
HKD1_k127_438542_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001489 226.0
HKD1_k127_438542_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000009783 208.0
HKD1_k127_438542_7 Protein of unknown function (DUF1059) - - - 0.000000000000000000000002193 109.0
HKD1_k127_438542_8 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000005993 64.0
HKD1_k127_4444996_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 359.0
HKD1_k127_4444996_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 293.0
HKD1_k127_4444996_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005634 252.0
HKD1_k127_4444996_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000001758 246.0
HKD1_k127_4444996_4 KR domain K07124 - - 0.0000000000000000000000000000000000000000000000000000000007739 204.0
HKD1_k127_4444996_5 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000236 119.0
HKD1_k127_4450175_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 2.632e-279 870.0
HKD1_k127_4450175_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 484.0
HKD1_k127_4450175_2 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 397.0
HKD1_k127_4450175_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 343.0
HKD1_k127_4450175_4 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 334.0
HKD1_k127_4450175_5 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000000000000000000000000002126 160.0
HKD1_k127_445607_0 alcohol dehydrogenase K17760 - 1.1.9.1 1.17e-234 747.0
HKD1_k127_445607_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 387.0
HKD1_k127_4472532_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 8.167e-255 802.0
HKD1_k127_4472532_1 nuclease activity K18828 - - 0.000000000000000000000000000000000000005615 157.0
HKD1_k127_4472532_2 - K18829 - - 0.00000000000000000000128 96.0
HKD1_k127_4472532_3 DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000004018 91.0
HKD1_k127_4500166_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1642.0
HKD1_k127_4500166_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1429.0
HKD1_k127_4500166_10 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 596.0
HKD1_k127_4500166_11 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 516.0
HKD1_k127_4500166_12 MCM2/3/5 family K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 462.0
HKD1_k127_4500166_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 473.0
HKD1_k127_4500166_14 Putative nucleotide-binding of sugar-metabolising enzyme K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 436.0
HKD1_k127_4500166_15 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 423.0
HKD1_k127_4500166_16 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 402.0
HKD1_k127_4500166_17 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
HKD1_k127_4500166_18 Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 396.0
HKD1_k127_4500166_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 391.0
HKD1_k127_4500166_2 Peptidase family M3 K01414 - 3.4.24.70 1.943e-284 888.0
HKD1_k127_4500166_20 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 351.0
HKD1_k127_4500166_21 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 334.0
HKD1_k127_4500166_22 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 308.0
HKD1_k127_4500166_23 helix_turn_helix, Lux Regulon K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 287.0
HKD1_k127_4500166_24 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001267 284.0
HKD1_k127_4500166_25 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001961 272.0
HKD1_k127_4500166_26 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009411 269.0
HKD1_k127_4500166_27 Class II Aldolase and Adducin N-terminal domain K22130 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000002428 247.0
HKD1_k127_4500166_28 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
HKD1_k127_4500166_29 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000006611 199.0
HKD1_k127_4500166_3 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 1.368e-282 878.0
HKD1_k127_4500166_30 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000006385 171.0
HKD1_k127_4500166_31 Protein of unknown function (DUF2459) - - - 0.0000000000000000000000000000000000000001353 167.0
HKD1_k127_4500166_32 PFAM Glutaredoxin - - - 0.0000000000000000000000000000000000000002868 155.0
HKD1_k127_4500166_33 Asp Glu hydantoin racemase - - - 0.0000000000000000000000000000000000000892 149.0
HKD1_k127_4500166_34 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000007 142.0
HKD1_k127_4500166_35 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000002087 142.0
HKD1_k127_4500166_36 Glutaredoxin - - - 0.000000000000000000000000000000275 132.0
HKD1_k127_4500166_37 - - - - 0.0000000000000000000003048 104.0
HKD1_k127_4500166_38 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000003347 91.0
HKD1_k127_4500166_39 - - - - 0.000000000000003404 80.0
HKD1_k127_4500166_4 ABC-type Fe3 transport system permease component K02011 - - 3.112e-258 807.0
HKD1_k127_4500166_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.654e-219 686.0
HKD1_k127_4500166_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 3.226e-209 664.0
HKD1_k127_4500166_7 ABC-type Fe3 transport system, periplasmic component - - - 2.259e-201 637.0
HKD1_k127_4500166_8 Belongs to the thiolase family K00626 - 2.3.1.9 1.847e-198 625.0
HKD1_k127_4500166_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 596.0
HKD1_k127_4503908_0 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 441.0
HKD1_k127_4503908_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 402.0
HKD1_k127_4503908_2 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
HKD1_k127_4503908_3 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000000598 149.0
HKD1_k127_4653232_0 Belongs to the malic enzymes family K00029 - 1.1.1.40 3.45e-313 976.0
HKD1_k127_4653232_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.314e-255 793.0
HKD1_k127_4653232_10 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 569.0
HKD1_k127_4653232_11 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 527.0
HKD1_k127_4653232_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 481.0
HKD1_k127_4653232_13 LysM domain K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 463.0
HKD1_k127_4653232_14 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 370.0
HKD1_k127_4653232_15 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
HKD1_k127_4653232_16 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 330.0
HKD1_k127_4653232_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 313.0
HKD1_k127_4653232_18 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 309.0
HKD1_k127_4653232_19 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006461 296.0
HKD1_k127_4653232_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 4.939e-253 797.0
HKD1_k127_4653232_20 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001036 241.0
HKD1_k127_4653232_21 Iron-sulfur cluster assembly transcription factor K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000002306 239.0
HKD1_k127_4653232_22 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000141 233.0
HKD1_k127_4653232_23 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000003825 185.0
HKD1_k127_4653232_24 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000002747 189.0
HKD1_k127_4653232_25 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000005348 177.0
HKD1_k127_4653232_26 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.000000000000000000000000000000000000000000005861 168.0
HKD1_k127_4653232_27 protocatechuate 3,4-dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000002921 163.0
HKD1_k127_4653232_28 Iron-sulphur cluster assembly - - - 0.00000000000000000000000002844 110.0
HKD1_k127_4653232_29 - - - - 0.0000000000000000000000001099 108.0
HKD1_k127_4653232_3 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.362e-249 785.0
HKD1_k127_4653232_30 Sporulation related domain K03749 - - 0.00000000000000000001154 101.0
HKD1_k127_4653232_31 colicin v production K03558 - - 0.0000000000001936 76.0
HKD1_k127_4653232_32 Entericidin EcnA/B family - - - 0.00002902 50.0
HKD1_k127_4653232_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.268e-248 772.0
HKD1_k127_4653232_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 3.711e-229 716.0
HKD1_k127_4653232_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.574e-220 688.0
HKD1_k127_4653232_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 605.0
HKD1_k127_4653232_8 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 585.0
HKD1_k127_4653232_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 566.0
HKD1_k127_4688674_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0 1129.0
HKD1_k127_4688674_1 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
HKD1_k127_4688674_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 305.0
HKD1_k127_4688674_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000006159 247.0
HKD1_k127_4688674_4 Domain of unknown function (DUF1974) K06445 GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000001938 235.0
HKD1_k127_4688674_5 - K07112 - - 0.000000000000000000000000000000000000000000000000000000000000001611 223.0
HKD1_k127_4688674_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000001214 153.0
HKD1_k127_4688674_7 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000009296 134.0
HKD1_k127_4688674_8 cytochrome C oxidoreductase subunit B - - - 0.000000000000000000006486 95.0
HKD1_k127_47443_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.689e-276 858.0
HKD1_k127_47443_1 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 333.0
HKD1_k127_47443_2 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000257 244.0
HKD1_k127_4782623_0 major facilitator superfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 591.0
HKD1_k127_4782623_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 434.0
HKD1_k127_4782623_2 Multidrug resistance efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 404.0
HKD1_k127_4782623_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
HKD1_k127_4782623_4 transcriptional regulator K03712 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0044212,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071236,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000008143 143.0
HKD1_k127_4782623_5 Transcriptional regulator - - - 0.00000000000000000000000000000001041 130.0
HKD1_k127_4821761_0 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 595.0
HKD1_k127_4821761_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 520.0
HKD1_k127_4821761_10 nitroreductase - - - 0.0000000000000000000000000000000000000000000003205 180.0
HKD1_k127_4821761_11 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000501 127.0
HKD1_k127_4821761_12 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000003463 79.0
HKD1_k127_4821761_13 - - - - 0.000000000417 65.0
HKD1_k127_4821761_14 - - - - 0.000000004418 68.0
HKD1_k127_4821761_2 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 371.0
HKD1_k127_4821761_3 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 336.0
HKD1_k127_4821761_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 290.0
HKD1_k127_4821761_5 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002743 291.0
HKD1_k127_4821761_6 Aldo keto - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
HKD1_k127_4821761_7 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000000001897 217.0
HKD1_k127_4821761_8 - - - - 0.00000000000000000000000000000000000000000000000000001494 197.0
HKD1_k127_4821761_9 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000004791 181.0
HKD1_k127_5007840_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 357.0
HKD1_k127_5007840_1 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.00000000000000000000000000000000000000000000000000008844 198.0
HKD1_k127_5007840_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000008457 123.0
HKD1_k127_5027412_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 514.0
HKD1_k127_5027412_1 fad dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 304.0
HKD1_k127_5071051_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.018e-257 824.0
HKD1_k127_5071051_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 585.0
HKD1_k127_5071051_2 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 571.0
HKD1_k127_5071051_3 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 485.0
HKD1_k127_5071051_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 462.0
HKD1_k127_5071051_5 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 370.0
HKD1_k127_5071051_6 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000000000000000000000000000000000000000002084 235.0
HKD1_k127_5071051_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000002411 207.0
HKD1_k127_5071051_8 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.00000000000000000000000000000000000000000000000000001795 188.0
HKD1_k127_5071051_9 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.00000000000000138 76.0
HKD1_k127_5075505_0 Efflux pump K03296,K18138,K18322 - - 4.05e-322 1001.0
HKD1_k127_5075505_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.399e-314 970.0
HKD1_k127_5075505_10 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000005095 172.0
HKD1_k127_5075505_11 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000005992 188.0
HKD1_k127_5075505_12 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000002785 148.0
HKD1_k127_5075505_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000007295 114.0
HKD1_k127_5075505_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000002826 114.0
HKD1_k127_5075505_15 - - - - 0.0000000000000002856 86.0
HKD1_k127_5075505_16 Rhodanese-like domain - - - 0.00000000000004354 81.0
HKD1_k127_5075505_17 - - - - 0.0000000000005931 76.0
HKD1_k127_5075505_2 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 521.0
HKD1_k127_5075505_3 Protein of unknown function (DUF692) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 433.0
HKD1_k127_5075505_4 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 454.0
HKD1_k127_5075505_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 417.0
HKD1_k127_5075505_6 acetyl-CoA hydrolase K18288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 369.0
HKD1_k127_5075505_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000008127 236.0
HKD1_k127_5075505_8 Cupin - - - 0.0000000000000000000000000000000000000000000000000000002909 198.0
HKD1_k127_5075505_9 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000002482 184.0
HKD1_k127_5089768_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1549.0
HKD1_k127_5089768_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1296.0
HKD1_k127_5089768_10 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 547.0
HKD1_k127_5089768_11 Sigma-54 interaction domain K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 546.0
HKD1_k127_5089768_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 486.0
HKD1_k127_5089768_13 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 428.0
HKD1_k127_5089768_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 412.0
HKD1_k127_5089768_15 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 403.0
HKD1_k127_5089768_16 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 401.0
HKD1_k127_5089768_17 SMART AAA ATPase K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 370.0
HKD1_k127_5089768_18 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 356.0
HKD1_k127_5089768_19 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 338.0
HKD1_k127_5089768_2 Belongs to the IlvD Edd family - - - 1.503e-277 867.0
HKD1_k127_5089768_20 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 319.0
HKD1_k127_5089768_21 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 332.0
HKD1_k127_5089768_22 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 319.0
HKD1_k127_5089768_23 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 299.0
HKD1_k127_5089768_24 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 302.0
HKD1_k127_5089768_25 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001829 278.0
HKD1_k127_5089768_26 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004747 246.0
HKD1_k127_5089768_27 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006401 243.0
HKD1_k127_5089768_28 Ami_2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000004004 224.0
HKD1_k127_5089768_29 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000003344 187.0
HKD1_k127_5089768_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.339e-273 851.0
HKD1_k127_5089768_30 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000002818 189.0
HKD1_k127_5089768_31 Thioredoxin-like - - - 0.00000000000000000000000000000000000000001024 161.0
HKD1_k127_5089768_32 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000001176 161.0
HKD1_k127_5089768_33 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000001881 146.0
HKD1_k127_5089768_34 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000001005 143.0
HKD1_k127_5089768_35 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000008694 134.0
HKD1_k127_5089768_36 YGGT family K02221 - - 0.000000000000000000000000000000002376 137.0
HKD1_k127_5089768_37 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000001934 112.0
HKD1_k127_5089768_38 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000001803 81.0
HKD1_k127_5089768_39 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000000003307 83.0
HKD1_k127_5089768_4 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.937e-251 781.0
HKD1_k127_5089768_40 - K06950 - - 0.00000000004843 70.0
HKD1_k127_5089768_41 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.000000002953 64.0
HKD1_k127_5089768_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 1.852e-246 773.0
HKD1_k127_5089768_6 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.863e-214 670.0
HKD1_k127_5089768_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.504e-201 647.0
HKD1_k127_5089768_8 type II secretion system protein K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 560.0
HKD1_k127_5089768_9 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 552.0
HKD1_k127_5107146_0 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000001465 171.0
HKD1_k127_5107146_1 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000004232 158.0
HKD1_k127_5107146_2 Protein of unknown function (DUF1211) - - - 0.00000000000000000000001243 107.0
HKD1_k127_5107146_3 - - - - 0.0000000000000008973 82.0
HKD1_k127_5123570_0 Transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000059 172.0
HKD1_k127_5123570_1 Cupredoxin-like domain - - - 0.000000000000000000000000000000000004221 139.0
HKD1_k127_5123570_2 Iron permease FTR1 family K07243 - - 0.000000000000000000000003418 104.0
HKD1_k127_512404_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 2.044e-291 921.0
HKD1_k127_512404_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 578.0
HKD1_k127_512404_2 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 564.0
HKD1_k127_512404_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 472.0
HKD1_k127_512404_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 449.0
HKD1_k127_512404_5 PGAP1-like protein - - - 0.0000000000000000000002904 110.0
HKD1_k127_5138140_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.152e-237 746.0
HKD1_k127_5138140_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 496.0
HKD1_k127_5138140_10 Type III secretion system lipoprotein chaperone (YscW) - - - 0.0000000000000000000000004706 110.0
HKD1_k127_5138140_11 - - - - 0.000000000000000000001609 103.0
HKD1_k127_5138140_12 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000000004402 98.0
HKD1_k127_5138140_13 Flagellar protein YcgR - - - 0.00000000000003099 83.0
HKD1_k127_5138140_14 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000008858 86.0
HKD1_k127_5138140_15 Flagellar protein FliT K02423 - - 0.00000000000188 75.0
HKD1_k127_5138140_16 Flagellar regulator YcgR - - - 0.000000000004935 76.0
HKD1_k127_5138140_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 309.0
HKD1_k127_5138140_3 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000142 289.0
HKD1_k127_5138140_4 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000001262 231.0
HKD1_k127_5138140_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000137 193.0
HKD1_k127_5138140_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000001003 174.0
HKD1_k127_5138140_7 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000001468 151.0
HKD1_k127_5138140_8 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000000000000000000001446 127.0
HKD1_k127_5138140_9 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000009166 130.0
HKD1_k127_5140728_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1172.0
HKD1_k127_5140728_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 7.352e-302 940.0
HKD1_k127_5140728_10 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 382.0
HKD1_k127_5140728_11 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 382.0
HKD1_k127_5140728_12 Tripartite ATP-independent periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 353.0
HKD1_k127_5140728_13 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 338.0
HKD1_k127_5140728_14 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 335.0
HKD1_k127_5140728_15 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 341.0
HKD1_k127_5140728_16 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
HKD1_k127_5140728_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009545 285.0
HKD1_k127_5140728_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000001504 252.0
HKD1_k127_5140728_19 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000008574 254.0
HKD1_k127_5140728_2 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 4.575e-218 702.0
HKD1_k127_5140728_20 signal peptide protein - - - 0.0000000000000000000000000000000000000000000005808 175.0
HKD1_k127_5140728_21 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000002148 160.0
HKD1_k127_5140728_22 Protein of unknown function (DUF3567) - - - 0.00000000000000000000008889 100.0
HKD1_k127_5140728_23 cobalamin synthesis protein, P47K - GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000004342 55.0
HKD1_k127_5140728_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 6.035e-210 660.0
HKD1_k127_5140728_4 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.514e-201 638.0
HKD1_k127_5140728_5 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 8.069e-199 633.0
HKD1_k127_5140728_6 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 580.0
HKD1_k127_5140728_7 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 563.0
HKD1_k127_5140728_8 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 479.0
HKD1_k127_5140728_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 398.0
HKD1_k127_5141557_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1020.0
HKD1_k127_5141557_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1005.0
HKD1_k127_5141557_10 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 483.0
HKD1_k127_5141557_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 463.0
HKD1_k127_5141557_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 423.0
HKD1_k127_5141557_13 chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 404.0
HKD1_k127_5141557_14 Abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 404.0
HKD1_k127_5141557_15 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 383.0
HKD1_k127_5141557_16 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 375.0
HKD1_k127_5141557_17 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 374.0
HKD1_k127_5141557_18 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 351.0
HKD1_k127_5141557_19 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 350.0
HKD1_k127_5141557_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.661e-277 858.0
HKD1_k127_5141557_20 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 364.0
HKD1_k127_5141557_21 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 329.0
HKD1_k127_5141557_22 Pfam:AmoA K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 328.0
HKD1_k127_5141557_23 Lysine exporter protein (Lyse ygga) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002573 244.0
HKD1_k127_5141557_24 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000002991 241.0
HKD1_k127_5141557_25 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000000000000003087 231.0
HKD1_k127_5141557_26 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000001115 207.0
HKD1_k127_5141557_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000007559 194.0
HKD1_k127_5141557_28 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000005481 192.0
HKD1_k127_5141557_29 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000001131 183.0
HKD1_k127_5141557_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.263e-263 816.0
HKD1_k127_5141557_30 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000001373 186.0
HKD1_k127_5141557_31 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000005264 183.0
HKD1_k127_5141557_32 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000000003308 173.0
HKD1_k127_5141557_33 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000004418 180.0
HKD1_k127_5141557_34 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000002601 166.0
HKD1_k127_5141557_35 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000001155 142.0
HKD1_k127_5141557_36 PFAM Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000001111 141.0
HKD1_k127_5141557_38 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001249 131.0
HKD1_k127_5141557_39 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000002192 109.0
HKD1_k127_5141557_4 Tripartite tricarboxylate transporter TctA family K07793 - - 9.261e-215 676.0
HKD1_k127_5141557_40 Universal stress protein - - - 0.0000000000000000000000404 106.0
HKD1_k127_5141557_41 ATP synthase I chain K02116 - - 0.00000000000000000002365 94.0
HKD1_k127_5141557_42 TonB family K03832 - - 0.0000000000000000001267 95.0
HKD1_k127_5141557_43 Helix-turn-helix XRE-family like proteins K07726 - - 0.00000000000000000169 88.0
HKD1_k127_5141557_44 Belongs to the UPF0235 family K09131 - - 0.0000000000002448 82.0
HKD1_k127_5141557_45 Protein involved in outer membrane biogenesis - - - 0.000005681 59.0
HKD1_k127_5141557_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.359e-213 685.0
HKD1_k127_5141557_6 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 6.018e-206 652.0
HKD1_k127_5141557_7 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 585.0
HKD1_k127_5141557_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 529.0
HKD1_k127_5141557_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 489.0
HKD1_k127_5149400_0 5'-nucleotidase, C-terminal domain K11751,K17224 - 3.1.3.5,3.6.1.45 1.65e-289 908.0
HKD1_k127_5149400_1 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 352.0
HKD1_k127_5149400_10 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000009338 111.0
HKD1_k127_5149400_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000007748 95.0
HKD1_k127_5149400_2 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008007 252.0
HKD1_k127_5149400_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003786 263.0
HKD1_k127_5149400_4 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000002228 221.0
HKD1_k127_5149400_5 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
HKD1_k127_5149400_6 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000002122 164.0
HKD1_k127_5149400_7 oxidation protein K17227 - - 0.0000000000000000000000000000000000000001261 153.0
HKD1_k127_5149400_8 Thioredoxin-like - - - 0.00000000000000000000000000000000000007005 148.0
HKD1_k127_5149400_9 Peptidase S24-like - - - 0.0000000000000000000000000000005655 127.0
HKD1_k127_5192514_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.714e-321 991.0
HKD1_k127_5192514_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 531.0
HKD1_k127_5192514_2 GntR family K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 355.0
HKD1_k127_5192514_3 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 282.0
HKD1_k127_5192514_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002259 207.0
HKD1_k127_5192514_5 Succinate dehydrogenase cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000001408 162.0
HKD1_k127_5192514_6 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.0000000000000000000000000000000000000476 149.0
HKD1_k127_5195547_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 6.981e-298 935.0
HKD1_k127_5195547_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.097e-220 692.0
HKD1_k127_5195547_10 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 418.0
HKD1_k127_5195547_11 3'-5' exonuclease K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 382.0
HKD1_k127_5195547_12 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 353.0
HKD1_k127_5195547_13 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 342.0
HKD1_k127_5195547_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 322.0
HKD1_k127_5195547_15 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 276.0
HKD1_k127_5195547_16 PFAM Fatty acid desaturase K00496 - 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
HKD1_k127_5195547_17 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001102 267.0
HKD1_k127_5195547_18 phosphoribosyltransferase K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001618 261.0
HKD1_k127_5195547_19 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000004735 245.0
HKD1_k127_5195547_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.409e-212 667.0
HKD1_k127_5195547_20 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000003467 214.0
HKD1_k127_5195547_21 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000000000000000000000003644 214.0
HKD1_k127_5195547_22 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000008106 211.0
HKD1_k127_5195547_23 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000006759 197.0
HKD1_k127_5195547_24 Tetratricopeptide repeat K02656 - - 0.00000000000000000000000000000000000000000000000000000008228 205.0
HKD1_k127_5195547_25 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000003543 185.0
HKD1_k127_5195547_26 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000001966 149.0
HKD1_k127_5195547_27 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000001199 145.0
HKD1_k127_5195547_28 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000003174 126.0
HKD1_k127_5195547_29 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000004004 123.0
HKD1_k127_5195547_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.858e-199 630.0
HKD1_k127_5195547_30 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000001803 78.0
HKD1_k127_5195547_31 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000002135 76.0
HKD1_k127_5195547_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 606.0
HKD1_k127_5195547_5 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 588.0
HKD1_k127_5195547_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 561.0
HKD1_k127_5195547_7 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 557.0
HKD1_k127_5195547_8 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 466.0
HKD1_k127_5195547_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 439.0
HKD1_k127_5211109_0 Peptidase S8 S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
HKD1_k127_5211109_1 - - - - 0.000000000000000000000000000000000000000000000000000001873 215.0
HKD1_k127_5211109_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000003352 187.0
HKD1_k127_5211109_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000007604 172.0
HKD1_k127_5211109_4 - - - - 0.000000000000000000000000000000000001644 154.0
HKD1_k127_5211109_5 - - - - 0.000000000000000000001883 110.0
HKD1_k127_5238991_0 - - - - 0.0000000000000000000000000000000000006132 156.0
HKD1_k127_5238991_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000002271 101.0
HKD1_k127_5283393_0 Berberine and berberine like - - - 4.133e-272 840.0
HKD1_k127_5283393_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 448.0
HKD1_k127_5283393_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 434.0
HKD1_k127_5283393_3 Bacterial regulatory proteins, luxR family K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002556 248.0
HKD1_k127_5283393_4 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
HKD1_k127_5283393_5 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000008936 237.0
HKD1_k127_5283393_6 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000003489 165.0
HKD1_k127_5283393_7 Belongs to the N-Me-Phe pilin family K02650 - - 0.00001529 52.0
HKD1_k127_5287200_0 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000006298 140.0
HKD1_k127_5287200_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000186 119.0
HKD1_k127_5287200_2 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000007285 111.0
HKD1_k127_5294240_0 twitching motility protein K02669,K12203 - - 1.128e-211 660.0
HKD1_k127_5294240_1 PFAM Type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 572.0
HKD1_k127_5294240_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001112 236.0
HKD1_k127_5294240_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000007783 59.0
HKD1_k127_5301629_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 510.0
HKD1_k127_5301629_1 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 398.0
HKD1_k127_5301629_2 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 391.0
HKD1_k127_5301629_3 KR domain K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 332.0
HKD1_k127_5301629_4 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.000000000000000000000000000000000000000000000000007007 182.0
HKD1_k127_5301629_5 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000005346 164.0
HKD1_k127_5301629_6 SnoaL-like domain - - - 0.00000000000000000000000000000001204 138.0
HKD1_k127_5301629_7 Zinc-finger domain - - - 0.00000000000000000000997 106.0
HKD1_k127_5311373_0 ABC transporter transmembrane region K06147 - - 3.462e-257 809.0
HKD1_k127_5311373_1 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 543.0
HKD1_k127_5311373_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009838 293.0
HKD1_k127_5311373_11 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000002182 257.0
HKD1_k127_5311373_12 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000007467 248.0
HKD1_k127_5311373_13 Acyl-CoA hydrolase K10806 - - 0.00000000000000000000000000000000000000000000000000000004058 200.0
HKD1_k127_5311373_14 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000005467 178.0
HKD1_k127_5311373_15 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000002593 161.0
HKD1_k127_5311373_16 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.000000000000000000000000000009311 125.0
HKD1_k127_5311373_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 544.0
HKD1_k127_5311373_3 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 396.0
HKD1_k127_5311373_4 acid transport system permease K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 386.0
HKD1_k127_5311373_5 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 379.0
HKD1_k127_5311373_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 320.0
HKD1_k127_5311373_7 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 316.0
HKD1_k127_5311373_8 Amino acid ABC transporter substrate-binding protein K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 317.0
HKD1_k127_5311373_9 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 311.0
HKD1_k127_5360605_0 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 7.339e-232 728.0
HKD1_k127_5360605_1 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 591.0
HKD1_k127_5360605_10 regulator - - - 0.00000000000001055 81.0
HKD1_k127_5360605_11 - - - - 0.000000000006715 72.0
HKD1_k127_5360605_12 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.0001941 54.0
HKD1_k127_5360605_2 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 422.0
HKD1_k127_5360605_3 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 396.0
HKD1_k127_5360605_4 PFAM LrgB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 305.0
HKD1_k127_5360605_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 299.0
HKD1_k127_5360605_6 Nicotinamidase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 284.0
HKD1_k127_5360605_7 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000003327 165.0
HKD1_k127_5360605_8 LrgA family K06518 - - 0.0000000000000000000000000000008809 128.0
HKD1_k127_5360605_9 Mitomycin resistance protein K07343 - - 0.00000000000000000000000004825 115.0
HKD1_k127_5447630_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1564.0
HKD1_k127_5447630_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1260.0
HKD1_k127_5447630_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.113e-236 734.0
HKD1_k127_5447630_11 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 3.135e-236 743.0
HKD1_k127_5447630_12 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 1.846e-222 700.0
HKD1_k127_5447630_13 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 9.791e-212 672.0
HKD1_k127_5447630_14 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.495e-209 658.0
HKD1_k127_5447630_15 Belongs to the HypD family K04654 - - 6.728e-198 625.0
HKD1_k127_5447630_16 Belongs to the enoyl-CoA hydratase isomerase family K19640 - - 1.198e-197 635.0
HKD1_k127_5447630_17 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 1.282e-195 647.0
HKD1_k127_5447630_18 NAD(P)H-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 616.0
HKD1_k127_5447630_19 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 609.0
HKD1_k127_5447630_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1021.0
HKD1_k127_5447630_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 578.0
HKD1_k127_5447630_21 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 574.0
HKD1_k127_5447630_22 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 531.0
HKD1_k127_5447630_23 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 495.0
HKD1_k127_5447630_24 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 487.0
HKD1_k127_5447630_25 serine protease K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 491.0
HKD1_k127_5447630_26 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 483.0
HKD1_k127_5447630_27 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 475.0
HKD1_k127_5447630_28 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 475.0
HKD1_k127_5447630_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 473.0
HKD1_k127_5447630_3 Nickel-dependent hydrogenase K06281 - 1.12.99.6 5.255e-316 975.0
HKD1_k127_5447630_30 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 453.0
HKD1_k127_5447630_31 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 449.0
HKD1_k127_5447630_32 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 429.0
HKD1_k127_5447630_33 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 422.0
HKD1_k127_5447630_34 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 397.0
HKD1_k127_5447630_35 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 417.0
HKD1_k127_5447630_36 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 402.0
HKD1_k127_5447630_37 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 387.0
HKD1_k127_5447630_38 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 372.0
HKD1_k127_5447630_39 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 360.0
HKD1_k127_5447630_4 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.928e-302 945.0
HKD1_k127_5447630_40 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 322.0
HKD1_k127_5447630_41 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 310.0
HKD1_k127_5447630_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 304.0
HKD1_k127_5447630_43 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 305.0
HKD1_k127_5447630_44 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 297.0
HKD1_k127_5447630_45 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 287.0
HKD1_k127_5447630_46 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 266.0
HKD1_k127_5447630_47 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005429 265.0
HKD1_k127_5447630_48 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
HKD1_k127_5447630_49 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002352 283.0
HKD1_k127_5447630_5 Fumarase C C-terminus K01744 - 4.3.1.1 5.743e-271 838.0
HKD1_k127_5447630_50 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003067 239.0
HKD1_k127_5447630_51 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000008375 237.0
HKD1_k127_5447630_52 phosphinothricin N-acetyltransferase activity K09181 - - 0.0000000000000000000000000000000000000000000000000000000000002096 222.0
HKD1_k127_5447630_53 membrane - - - 0.000000000000000000000000000000000000000000000000000000000002029 216.0
HKD1_k127_5447630_54 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000000000000000004219 212.0
HKD1_k127_5447630_55 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000503 210.0
HKD1_k127_5447630_56 Ni,Fe-hydrogenase I large subunit - - - 0.00000000000000000000000000000000000000000000000000000004496 210.0
HKD1_k127_5447630_57 - - - - 0.000000000000000000000000000000000000000000000000000001168 209.0
HKD1_k127_5447630_58 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000003624 176.0
HKD1_k127_5447630_59 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000001431 166.0
HKD1_k127_5447630_6 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.387e-269 838.0
HKD1_k127_5447630_60 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000007051 158.0
HKD1_k127_5447630_61 Protein of unknown function (DUF3302) - - - 0.00000000000000000000000000000000001518 142.0
HKD1_k127_5447630_62 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.000000000000000000000000000000004535 141.0
HKD1_k127_5447630_63 Hydrogenase-1 expression protein HyaE - - - 0.000000000000000000000000000000006293 138.0
HKD1_k127_5447630_64 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000003572 130.0
HKD1_k127_5447630_65 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000001225 128.0
HKD1_k127_5447630_66 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000157 127.0
HKD1_k127_5447630_67 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000001312 121.0
HKD1_k127_5447630_68 ferredoxin - - - 0.00000000000000000000000000008061 128.0
HKD1_k127_5447630_69 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000002694 110.0
HKD1_k127_5447630_7 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 9.03e-269 839.0
HKD1_k127_5447630_70 HupF/HypC family K04653 - - 0.000000000000000000000000166 108.0
HKD1_k127_5447630_71 Helix-turn-helix K21498 - - 0.000000000000000000000000971 108.0
HKD1_k127_5447630_72 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000001158 106.0
HKD1_k127_5447630_73 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000001696 103.0
HKD1_k127_5447630_74 Belongs to the rubredoxin family - - - 0.0000000000000000000001834 99.0
HKD1_k127_5447630_75 Ion channel - - - 0.000000000000000000001009 100.0
HKD1_k127_5447630_76 - - - - 0.00000000003605 67.0
HKD1_k127_5447630_77 - - - - 0.00000000094 62.0
HKD1_k127_5447630_78 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000001465 53.0
HKD1_k127_5447630_8 Prolyl oligopeptidase family - - - 1.212e-250 791.0
HKD1_k127_5447630_9 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 7.446e-246 764.0
HKD1_k127_5485206_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 360.0
HKD1_k127_5485206_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 341.0
HKD1_k127_5485206_2 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000003946 239.0
HKD1_k127_5485206_3 Patatin phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000008881 224.0
HKD1_k127_5485206_4 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000007535 113.0
HKD1_k127_5485206_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000005811 90.0
HKD1_k127_5485206_6 - - - - 0.000003462 50.0
HKD1_k127_5485206_7 FAD dependent oxidoreductase K07137 - - 0.000158 44.0
HKD1_k127_5528364_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002084 283.0
HKD1_k127_5536071_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 3.5e-322 999.0
HKD1_k127_5536071_1 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 3.042e-310 962.0
HKD1_k127_5536071_10 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 509.0
HKD1_k127_5536071_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 484.0
HKD1_k127_5536071_12 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 393.0
HKD1_k127_5536071_13 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 378.0
HKD1_k127_5536071_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 365.0
HKD1_k127_5536071_15 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 342.0
HKD1_k127_5536071_16 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 334.0
HKD1_k127_5536071_17 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
HKD1_k127_5536071_18 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 320.0
HKD1_k127_5536071_19 Divalent heavy-metal cations transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 289.0
HKD1_k127_5536071_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.541e-309 959.0
HKD1_k127_5536071_20 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001046 280.0
HKD1_k127_5536071_21 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000003698 242.0
HKD1_k127_5536071_22 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000001372 225.0
HKD1_k127_5536071_23 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000005 220.0
HKD1_k127_5536071_24 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000000000000001219 153.0
HKD1_k127_5536071_25 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000001457 100.0
HKD1_k127_5536071_26 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000003664 89.0
HKD1_k127_5536071_27 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000005777 59.0
HKD1_k127_5536071_28 META domain - - - 0.000003665 57.0
HKD1_k127_5536071_3 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.077e-256 796.0
HKD1_k127_5536071_4 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.239e-229 725.0
HKD1_k127_5536071_5 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 4.79e-226 714.0
HKD1_k127_5536071_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 579.0
HKD1_k127_5536071_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 569.0
HKD1_k127_5536071_8 SpoVR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 561.0
HKD1_k127_5536071_9 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 517.0
HKD1_k127_5562120_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 605.0
HKD1_k127_5562120_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 555.0
HKD1_k127_5562120_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 467.0
HKD1_k127_5562120_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 452.0
HKD1_k127_5562120_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 341.0
HKD1_k127_5562120_5 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005925 285.0
HKD1_k127_5562120_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000002326 244.0
HKD1_k127_5562120_7 Prolyl oligopeptidase K01322 - 3.4.21.26 0.000000000000000001135 88.0
HKD1_k127_5562390_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 6.535e-288 890.0
HKD1_k127_5562390_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 3.499e-269 845.0
HKD1_k127_5562390_10 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 462.0
HKD1_k127_5562390_11 Zn-dependent hydrolases including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 436.0
HKD1_k127_5562390_12 Cys/Met metabolism PLP-dependent enzyme K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 426.0
HKD1_k127_5562390_13 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 336.0
HKD1_k127_5562390_14 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
HKD1_k127_5562390_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 308.0
HKD1_k127_5562390_16 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001595 276.0
HKD1_k127_5562390_17 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000003325 245.0
HKD1_k127_5562390_18 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000005632 231.0
HKD1_k127_5562390_19 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
HKD1_k127_5562390_2 DNA helicase K03654 - 3.6.4.12 1.148e-222 715.0
HKD1_k127_5562390_20 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001153 232.0
HKD1_k127_5562390_21 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008455 225.0
HKD1_k127_5562390_22 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000002177 216.0
HKD1_k127_5562390_23 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000007702 211.0
HKD1_k127_5562390_24 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000001609 196.0
HKD1_k127_5562390_25 Lysine exporter protein (Lyse ygga) - - - 0.000000000000000000000000000000000000000000000000000000732 206.0
HKD1_k127_5562390_26 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000113 187.0
HKD1_k127_5562390_27 Lysine exporter protein LysE K11250 - - 0.000000000000000000000000000000000000000000000000002807 188.0
HKD1_k127_5562390_28 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000004582 185.0
HKD1_k127_5562390_29 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000009273 184.0
HKD1_k127_5562390_3 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 1.631e-220 687.0
HKD1_k127_5562390_30 - - - - 0.000000000000000000000000000000000000000000006401 184.0
HKD1_k127_5562390_31 cell division protein - - - 0.0000000000000000000000000000000000286 141.0
HKD1_k127_5562390_32 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000002413 136.0
HKD1_k127_5562390_33 Protein of unknown function (DUF2799) - - - 0.00000000000000000000000001103 119.0
HKD1_k127_5562390_35 membrane - - - 0.00000000002721 76.0
HKD1_k127_5562390_4 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.952e-211 672.0
HKD1_k127_5562390_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 1.808e-210 664.0
HKD1_k127_5562390_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.438e-198 626.0
HKD1_k127_5562390_7 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 599.0
HKD1_k127_5562390_8 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 551.0
HKD1_k127_5562390_9 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 520.0
HKD1_k127_5716089_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.026e-201 632.0
HKD1_k127_5716089_1 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 430.0
HKD1_k127_5716089_10 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000001204 179.0
HKD1_k127_5716089_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000378 178.0
HKD1_k127_5716089_12 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000000002424 148.0
HKD1_k127_5716089_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000000000004662 148.0
HKD1_k127_5716089_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000004123 100.0
HKD1_k127_5716089_15 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000009085 84.0
HKD1_k127_5716089_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 394.0
HKD1_k127_5716089_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 395.0
HKD1_k127_5716089_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 334.0
HKD1_k127_5716089_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 309.0
HKD1_k127_5716089_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 307.0
HKD1_k127_5716089_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000008636 266.0
HKD1_k127_5716089_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000001705 203.0
HKD1_k127_5716089_9 Psort location Extracellular, score K07126 - - 0.0000000000000000000000000000000000000000000000000008576 201.0
HKD1_k127_5978363_0 PFAM Acyl-CoA dehydrogenase K00252 - 1.3.8.6 1.571e-225 702.0
HKD1_k127_5978363_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 401.0
HKD1_k127_5978363_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000002979 171.0
HKD1_k127_5978363_3 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.000000000000000000000000000000000002948 149.0
HKD1_k127_5978363_4 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000003018 136.0
HKD1_k127_6002423_0 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001405 280.0
HKD1_k127_6002423_1 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000005483 181.0
HKD1_k127_6002423_2 Protein of unknown function (DUF533) - - - 0.000000000000000000004151 94.0
HKD1_k127_6002423_3 Hemerythrin HHE cation binding domain K07216 - - 0.00000005952 59.0
HKD1_k127_601879_0 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 464.0
HKD1_k127_601879_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 410.0
HKD1_k127_6020276_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1283.0
HKD1_k127_6020276_1 orn lys arg decarboxylase K01584 - 4.1.1.19 0.0 1249.0
HKD1_k127_6020276_10 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 9.175e-216 683.0
HKD1_k127_6020276_11 D-amino acid K00285 - 1.4.5.1 7.788e-212 663.0
HKD1_k127_6020276_12 Transmembrane secretion effector - - - 4.04e-200 640.0
HKD1_k127_6020276_13 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 640.0
HKD1_k127_6020276_14 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 661.0
HKD1_k127_6020276_15 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 550.0
HKD1_k127_6020276_16 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 524.0
HKD1_k127_6020276_17 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 515.0
HKD1_k127_6020276_18 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 527.0
HKD1_k127_6020276_19 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 512.0
HKD1_k127_6020276_2 C-terminal region of aryl-sulfatase - - - 0.0 1019.0
HKD1_k127_6020276_20 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 525.0
HKD1_k127_6020276_21 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 522.0
HKD1_k127_6020276_22 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 490.0
HKD1_k127_6020276_23 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 490.0
HKD1_k127_6020276_24 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 484.0
HKD1_k127_6020276_25 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 480.0
HKD1_k127_6020276_26 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 473.0
HKD1_k127_6020276_27 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 471.0
HKD1_k127_6020276_28 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 466.0
HKD1_k127_6020276_29 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 433.0
HKD1_k127_6020276_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.716e-302 940.0
HKD1_k127_6020276_30 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 430.0
HKD1_k127_6020276_31 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 447.0
HKD1_k127_6020276_32 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 405.0
HKD1_k127_6020276_33 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 418.0
HKD1_k127_6020276_34 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 392.0
HKD1_k127_6020276_35 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 386.0
HKD1_k127_6020276_36 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 407.0
HKD1_k127_6020276_37 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 373.0
HKD1_k127_6020276_38 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 361.0
HKD1_k127_6020276_39 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 365.0
HKD1_k127_6020276_4 PQQ enzyme repeat - - - 5.728e-302 932.0
HKD1_k127_6020276_40 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 366.0
HKD1_k127_6020276_41 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 351.0
HKD1_k127_6020276_42 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 352.0
HKD1_k127_6020276_43 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 348.0
HKD1_k127_6020276_44 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 345.0
HKD1_k127_6020276_45 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 336.0
HKD1_k127_6020276_46 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 346.0
HKD1_k127_6020276_47 KR domain K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 301.0
HKD1_k127_6020276_48 response regulator K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003001 289.0
HKD1_k127_6020276_49 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000009389 270.0
HKD1_k127_6020276_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.808e-273 853.0
HKD1_k127_6020276_50 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001138 253.0
HKD1_k127_6020276_51 carbon monoxide dehydrogenase K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001152 235.0
HKD1_k127_6020276_52 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000001338 261.0
HKD1_k127_6020276_53 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000001574 244.0
HKD1_k127_6020276_54 lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000002198 240.0
HKD1_k127_6020276_55 Sulfate permease family - - - 0.000000000000000000000000000000000000000000000000000000000000002124 244.0
HKD1_k127_6020276_56 - - - - 0.000000000000000000000000000000000000000000000000000000000000003237 224.0
HKD1_k127_6020276_57 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000006889 232.0
HKD1_k127_6020276_58 protein conserved in bacteria K04750 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
HKD1_k127_6020276_59 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000001284 213.0
HKD1_k127_6020276_6 Histidine kinase K07646 - 2.7.13.3 3.456e-267 852.0
HKD1_k127_6020276_60 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000003867 199.0
HKD1_k127_6020276_61 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000000000000001193 180.0
HKD1_k127_6020276_62 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000009704 169.0
HKD1_k127_6020276_63 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000004014 171.0
HKD1_k127_6020276_64 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000004938 177.0
HKD1_k127_6020276_65 PFAM Ankyrin K06867 - - 0.00000000000000000000000000000000000000000004227 168.0
HKD1_k127_6020276_66 curli production assembly transport component CsgG K06214,K13586 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0019867,GO:0022610,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0033036,GO:0042597,GO:0042710,GO:0042802,GO:0042886,GO:0044010,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0045184,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098552 - 0.000000000000000000000000000000000000002993 165.0
HKD1_k127_6020276_67 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000001649 151.0
HKD1_k127_6020276_68 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000002579 138.0
HKD1_k127_6020276_69 PFAM GYD family protein - - - 0.0000000000000000000000000000000007154 132.0
HKD1_k127_6020276_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 1.319e-250 784.0
HKD1_k127_6020276_70 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000004997 113.0
HKD1_k127_6020276_71 FabA-like domain - - - 0.000000000000000000000902 106.0
HKD1_k127_6020276_72 spectrin binding K15502,K19947 - 1.14.13.225 0.000000000000000002409 100.0
HKD1_k127_6020276_73 - - - - 0.00000000000000001736 89.0
HKD1_k127_6020276_74 Histidine kinase K20976 - - 0.00000000000000002264 97.0
HKD1_k127_6020276_75 Domain of unknown function (DUF1330) - - - 0.00000000000000007963 83.0
HKD1_k127_6020276_76 - - - - 0.0000000000000851 81.0
HKD1_k127_6020276_77 Cytochrome c - - - 0.0000000002202 69.0
HKD1_k127_6020276_78 serine threonine protein kinase K03587,K08884,K12132 - 2.7.11.1,3.4.16.4 0.00000002205 63.0
HKD1_k127_6020276_79 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000002324 62.0
HKD1_k127_6020276_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.057e-234 742.0
HKD1_k127_6020276_80 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00006562 55.0
HKD1_k127_6020276_9 Patatin-like phospholipase - - - 1.242e-219 699.0
HKD1_k127_602054_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 5.275e-204 641.0
HKD1_k127_602054_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 542.0
HKD1_k127_602054_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 348.0
HKD1_k127_602054_3 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000007345 82.0
HKD1_k127_602054_4 - - - - 0.0000000000223 74.0
HKD1_k127_6051404_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.295e-301 938.0
HKD1_k127_6051404_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.011e-263 820.0
HKD1_k127_6051404_10 depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008016 244.0
HKD1_k127_6051404_11 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000001317 190.0
HKD1_k127_6051404_12 nucleotidyltransferase activity - - - 0.0000000000000000000003642 109.0
HKD1_k127_6051404_13 - - - - 0.0000000000000001161 87.0
HKD1_k127_6051404_14 Dienelactone hydrolase - - - 0.000000005354 66.0
HKD1_k127_6051404_15 pathogenesis - - - 0.000004756 56.0
HKD1_k127_6051404_16 - - - - 0.0005617 48.0
HKD1_k127_6051404_2 amidohydrolase K01451 - 3.5.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 576.0
HKD1_k127_6051404_3 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 435.0
HKD1_k127_6051404_4 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 407.0
HKD1_k127_6051404_5 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 380.0
HKD1_k127_6051404_6 coenzyme F390 synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 379.0
HKD1_k127_6051404_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 362.0
HKD1_k127_6051404_8 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 296.0
HKD1_k127_6051404_9 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001241 245.0
HKD1_k127_6101733_0 belongs to the aldehyde dehydrogenase family K00146 - 1.2.1.39 3.728e-220 688.0
HKD1_k127_6101733_1 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 436.0
HKD1_k127_6101733_2 Major Facilitator - - - 0.0000000000000000000000009532 105.0
HKD1_k127_6111743_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.248e-243 770.0
HKD1_k127_6111743_1 Glucose / Sorbosone dehydrogenase - - - 1.521e-235 733.0
HKD1_k127_6111743_10 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000004216 233.0
HKD1_k127_6111743_11 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000005083 192.0
HKD1_k127_6111743_12 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000001167 168.0
HKD1_k127_6111743_13 - - - - 0.00000000000000000000000000000000000000000785 159.0
HKD1_k127_6111743_14 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000003611 164.0
HKD1_k127_6111743_15 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000004642 159.0
HKD1_k127_6111743_16 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000003896 151.0
HKD1_k127_6111743_17 Phasin protein - - - 0.0000000000000000000000000000003269 129.0
HKD1_k127_6111743_18 PFAM Cytochrome C K17230 - - 0.00000000000000000000000009948 120.0
HKD1_k127_6111743_19 F420H(2)-dependent quinone reductase - - - 0.0000000000000006015 86.0
HKD1_k127_6111743_2 TonB-dependent Receptor Plug K02014 - - 1.897e-217 698.0
HKD1_k127_6111743_20 epimerase K00091 - 1.1.1.219 0.0000124 56.0
HKD1_k127_6111743_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 583.0
HKD1_k127_6111743_4 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 503.0
HKD1_k127_6111743_5 LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 458.0
HKD1_k127_6111743_6 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 423.0
HKD1_k127_6111743_7 pyridine nucleotide-disulfide oxidoreductase family protein K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 312.0
HKD1_k127_6111743_8 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 250.0
HKD1_k127_6111743_9 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001424 258.0
HKD1_k127_6130851_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 2.683e-241 760.0
HKD1_k127_6130851_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 463.0
HKD1_k127_6130851_2 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 411.0
HKD1_k127_6130851_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000333 248.0
HKD1_k127_6130851_4 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000006797 245.0
HKD1_k127_6130851_5 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000000005327 94.0
HKD1_k127_6158049_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 512.0
HKD1_k127_6158049_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 443.0
HKD1_k127_6158049_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001954 257.0
HKD1_k127_6158049_3 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000001177 193.0
HKD1_k127_6158049_4 PFAM amidohydrolase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000005776 188.0
HKD1_k127_6158049_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000003818 138.0
HKD1_k127_6200214_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 375.0
HKD1_k127_6200214_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000006915 203.0
HKD1_k127_6205792_0 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 336.0
HKD1_k127_6205792_1 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001094 249.0
HKD1_k127_6215225_0 AcrB/AcrD/AcrF family - - - 0.0 1537.0
HKD1_k127_6215225_1 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 4.377e-212 668.0
HKD1_k127_6215225_2 Peptidase family M3 K01392 - 3.4.24.15 4.128e-195 631.0
HKD1_k127_6215225_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 402.0
HKD1_k127_6215225_4 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001044 273.0
HKD1_k127_6215225_5 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000005149 215.0
HKD1_k127_6215225_6 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.000000000000000000000000000000000000000002315 165.0
HKD1_k127_6220090_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 5e-324 1009.0
HKD1_k127_6220090_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 8.801e-320 989.0
HKD1_k127_6220090_10 cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 475.0
HKD1_k127_6220090_11 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 458.0
HKD1_k127_6220090_12 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 482.0
HKD1_k127_6220090_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 453.0
HKD1_k127_6220090_14 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 420.0
HKD1_k127_6220090_15 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 359.0
HKD1_k127_6220090_16 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 322.0
HKD1_k127_6220090_17 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 326.0
HKD1_k127_6220090_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 312.0
HKD1_k127_6220090_19 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 295.0
HKD1_k127_6220090_2 Molecular chaperone. Has ATPase activity K04079 - - 5.641e-295 919.0
HKD1_k127_6220090_20 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
HKD1_k127_6220090_21 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001849 265.0
HKD1_k127_6220090_22 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004264 271.0
HKD1_k127_6220090_23 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 254.0
HKD1_k127_6220090_24 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 259.0
HKD1_k127_6220090_25 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008576 254.0
HKD1_k127_6220090_26 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002555 255.0
HKD1_k127_6220090_27 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000006484 242.0
HKD1_k127_6220090_28 Proline racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000006106 237.0
HKD1_k127_6220090_29 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000000188 211.0
HKD1_k127_6220090_3 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 6.342e-268 836.0
HKD1_k127_6220090_30 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000000000001244 224.0
HKD1_k127_6220090_31 glycosylase K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000001989 193.0
HKD1_k127_6220090_32 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000004571 206.0
HKD1_k127_6220090_33 Copper resistance protein D - - - 0.0000000000000000000000000000000000003434 145.0
HKD1_k127_6220090_34 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000002734 140.0
HKD1_k127_6220090_35 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000001716 136.0
HKD1_k127_6220090_36 membrane - - - 0.0000000000000000000000000000000004169 136.0
HKD1_k127_6220090_37 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000002068 130.0
HKD1_k127_6220090_38 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000001081 123.0
HKD1_k127_6220090_39 PFAM Cytochrome c, class I - - - 0.00000000000000000000000008728 112.0
HKD1_k127_6220090_4 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.586e-232 736.0
HKD1_k127_6220090_40 cytochrome - - - 0.000000000000000000000001988 106.0
HKD1_k127_6220090_41 TM2 domain - - - 0.0000000000000000000218 96.0
HKD1_k127_6220090_42 Domain of unknown function (DUF1841) - - - 0.0000000001979 62.0
HKD1_k127_6220090_43 - - - - 0.000002502 54.0
HKD1_k127_6220090_44 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.00007549 48.0
HKD1_k127_6220090_5 Cysteine-rich domain - - - 1.54e-206 651.0
HKD1_k127_6220090_6 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 2.985e-199 629.0
HKD1_k127_6220090_7 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 568.0
HKD1_k127_6220090_8 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 514.0
HKD1_k127_6220090_9 ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 491.0
HKD1_k127_6246062_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.759e-233 739.0
HKD1_k127_6246062_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.125e-223 724.0
HKD1_k127_6246062_10 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000002885 209.0
HKD1_k127_6246062_11 CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000001911 167.0
HKD1_k127_6246062_12 Phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000235 122.0
HKD1_k127_6246062_13 FeoA K04758 - - 0.00000002482 61.0
HKD1_k127_6246062_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.325e-214 690.0
HKD1_k127_6246062_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 537.0
HKD1_k127_6246062_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 466.0
HKD1_k127_6246062_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 450.0
HKD1_k127_6246062_6 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 363.0
HKD1_k127_6246062_7 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 314.0
HKD1_k127_6246062_8 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 300.0
HKD1_k127_6246062_9 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007517 253.0
HKD1_k127_6282936_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 569.0
HKD1_k127_6282936_1 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 357.0
HKD1_k127_6301437_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1305.0
HKD1_k127_6301437_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 9.963e-224 700.0
HKD1_k127_6301437_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000001059 146.0
HKD1_k127_6301437_11 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000005584 70.0
HKD1_k127_6301437_12 - - - - 0.000000001255 62.0
HKD1_k127_6301437_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.304e-195 617.0
HKD1_k127_6301437_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 561.0
HKD1_k127_6301437_4 D-amino acid K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 470.0
HKD1_k127_6301437_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 468.0
HKD1_k127_6301437_6 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 412.0
HKD1_k127_6301437_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 363.0
HKD1_k127_6301437_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 343.0
HKD1_k127_6301437_9 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 320.0
HKD1_k127_6338383_0 Aminotransferase class I and II K09758 - 4.1.1.12 1.851e-259 810.0
HKD1_k127_6338383_1 Predicted Permease Membrane Region K07085 - - 2.585e-212 668.0
HKD1_k127_6338383_2 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001779 252.0
HKD1_k127_6350549_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 2351.0
HKD1_k127_6350549_1 DNA polymerase K02337 - 2.7.7.7 0.0 1283.0
HKD1_k127_6350549_10 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 599.0
HKD1_k127_6350549_12 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 566.0
HKD1_k127_6350549_13 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 529.0
HKD1_k127_6350549_14 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 489.0
HKD1_k127_6350549_15 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 477.0
HKD1_k127_6350549_16 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 472.0
HKD1_k127_6350549_17 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 462.0
HKD1_k127_6350549_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 446.0
HKD1_k127_6350549_19 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 436.0
HKD1_k127_6350549_2 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 2.478e-318 976.0
HKD1_k127_6350549_20 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 443.0
HKD1_k127_6350549_21 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 442.0
HKD1_k127_6350549_22 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 445.0
HKD1_k127_6350549_23 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 429.0
HKD1_k127_6350549_24 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 398.0
HKD1_k127_6350549_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 391.0
HKD1_k127_6350549_26 GAF domain K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 402.0
HKD1_k127_6350549_27 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 393.0
HKD1_k127_6350549_28 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 374.0
HKD1_k127_6350549_29 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 366.0
HKD1_k127_6350549_3 nitrite transporter K02575 - - 4.865e-309 952.0
HKD1_k127_6350549_30 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 367.0
HKD1_k127_6350549_31 META domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 351.0
HKD1_k127_6350549_32 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 353.0
HKD1_k127_6350549_33 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 333.0
HKD1_k127_6350549_34 Nitrate reductase delta subunit K00373 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 319.0
HKD1_k127_6350549_35 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 313.0
HKD1_k127_6350549_36 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 334.0
HKD1_k127_6350549_37 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 312.0
HKD1_k127_6350549_38 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 298.0
HKD1_k127_6350549_39 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 293.0
HKD1_k127_6350549_4 nitrite transmembrane transporter activity - - - 9.108e-269 856.0
HKD1_k127_6350549_40 ABC-2 family transporter protein K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 292.0
HKD1_k127_6350549_41 PFAM glycosyl transferase family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008545 292.0
HKD1_k127_6350549_42 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004655 287.0
HKD1_k127_6350549_43 ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000304 269.0
HKD1_k127_6350549_44 heptosyltransferase K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005304 265.0
HKD1_k127_6350549_45 Bacterial regulatory proteins, luxR family K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002198 256.0
HKD1_k127_6350549_46 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000004815 254.0
HKD1_k127_6350549_47 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009054 251.0
HKD1_k127_6350549_48 PFAM Glycosyl transferase, family 25 K07270 - - 0.0000000000000000000000000000000000000000000000000000000000000000007758 245.0
HKD1_k127_6350549_49 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000007215 229.0
HKD1_k127_6350549_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 3.251e-241 778.0
HKD1_k127_6350549_50 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000002699 239.0
HKD1_k127_6350549_51 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000003521 216.0
HKD1_k127_6350549_52 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000000000000118 199.0
HKD1_k127_6350549_53 - - - - 0.0000000000000000000000000000000000000000000000000000001801 215.0
HKD1_k127_6350549_54 alpha-galactosidase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000002601 203.0
HKD1_k127_6350549_55 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000001929 193.0
HKD1_k127_6350549_56 PFAM O-Antigen - - - 0.0000000000000000000000000000000000000000000000000004042 204.0
HKD1_k127_6350549_57 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000002081 183.0
HKD1_k127_6350549_58 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000001559 179.0
HKD1_k127_6350549_59 - - - - 0.00000000000000000000000000000000000000000000001592 183.0
HKD1_k127_6350549_6 Bacterial protein of unknown function (DUF853) K06915 - - 1.01e-236 741.0
HKD1_k127_6350549_60 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000009671 168.0
HKD1_k127_6350549_61 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000005479 176.0
HKD1_k127_6350549_62 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000003016 164.0
HKD1_k127_6350549_63 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000004617 164.0
HKD1_k127_6350549_64 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000001049 139.0
HKD1_k127_6350549_66 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000001882 147.0
HKD1_k127_6350549_67 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.000000000000000000000000000000002322 139.0
HKD1_k127_6350549_68 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000004013 135.0
HKD1_k127_6350549_69 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.0000000000000000000000000000002268 128.0
HKD1_k127_6350549_7 ribonuclease, Rne Rng family K08301 - - 4.45e-227 712.0
HKD1_k127_6350549_70 PEP-CTERM motif - - - 0.0000000000000000000000000000008648 131.0
HKD1_k127_6350549_71 PFAM small multidrug resistance protein K11741 - - 0.000000000000000000000000000004136 123.0
HKD1_k127_6350549_72 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000311 124.0
HKD1_k127_6350549_73 - - - - 0.00000000000000000002003 100.0
HKD1_k127_6350549_74 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000184 103.0
HKD1_k127_6350549_75 - - - - 0.00000000000000006511 84.0
HKD1_k127_6350549_76 KTSC domain - - - 0.0000000000000002381 93.0
HKD1_k127_6350549_78 Transglycosylase associated protein - - - 0.0000000000000309 81.0
HKD1_k127_6350549_8 ERAP1-like C-terminal domain K01256 - 3.4.11.2 1.219e-207 676.0
HKD1_k127_6350549_82 - - - - 0.00002703 46.0
HKD1_k127_6350549_83 Domain of unknown function (DUF4124) - - - 0.0008962 48.0
HKD1_k127_6350549_9 Belongs to the GARS family K01945 - 6.3.4.13 1.3e-202 640.0
HKD1_k127_6351712_0 Peptidase M61 - - - 8.684e-221 704.0
HKD1_k127_6351712_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.132e-213 672.0
HKD1_k127_6351712_10 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000005247 184.0
HKD1_k127_6351712_11 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00003259 46.0
HKD1_k127_6351712_12 FR47-like protein - - - 0.0001132 55.0
HKD1_k127_6351712_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 508.0
HKD1_k127_6351712_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 387.0
HKD1_k127_6351712_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 340.0
HKD1_k127_6351712_5 Anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 322.0
HKD1_k127_6351712_6 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 325.0
HKD1_k127_6351712_7 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000008777 258.0
HKD1_k127_6351712_8 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005296 239.0
HKD1_k127_6351712_9 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000005458 216.0
HKD1_k127_6352205_0 Ethylbenzene dehydrogenase - - - 1.002e-206 653.0
HKD1_k127_6352205_1 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 423.0
HKD1_k127_6352205_2 Transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 403.0
HKD1_k127_6352205_3 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 312.0
HKD1_k127_6352205_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004823 230.0
HKD1_k127_6352205_6 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000959 67.0
HKD1_k127_6398440_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1440.0
HKD1_k127_6398440_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.631e-252 796.0
HKD1_k127_6398440_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 509.0
HKD1_k127_6398440_11 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 496.0
HKD1_k127_6398440_12 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 442.0
HKD1_k127_6398440_13 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 423.0
HKD1_k127_6398440_14 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 431.0
HKD1_k127_6398440_15 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 394.0
HKD1_k127_6398440_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 403.0
HKD1_k127_6398440_17 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 391.0
HKD1_k127_6398440_18 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 373.0
HKD1_k127_6398440_19 Belongs to the ABC transporter superfamily K02010,K02052,K11072 - 3.6.3.30,3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 347.0
HKD1_k127_6398440_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 9.814e-251 779.0
HKD1_k127_6398440_20 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
HKD1_k127_6398440_21 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 334.0
HKD1_k127_6398440_22 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 309.0
HKD1_k127_6398440_23 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
HKD1_k127_6398440_24 PFAM inositol monophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001526 279.0
HKD1_k127_6398440_25 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001769 274.0
HKD1_k127_6398440_26 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000001844 259.0
HKD1_k127_6398440_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005168 250.0
HKD1_k127_6398440_28 Metal dependent phosphohydrolases with conserved 'HD' motif. K21196 - 1.13.11.78 0.00000000000000000000000000000000000000000000000000000000000000001078 231.0
HKD1_k127_6398440_29 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000001641 224.0
HKD1_k127_6398440_3 Dynamin family - - - 7.974e-197 634.0
HKD1_k127_6398440_30 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000003115 220.0
HKD1_k127_6398440_31 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000422 231.0
HKD1_k127_6398440_32 - - - - 0.000000000000000000000000000000000000000000000000001194 193.0
HKD1_k127_6398440_33 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000000000000000000000001613 183.0
HKD1_k127_6398440_34 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000002084 173.0
HKD1_k127_6398440_35 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000004445 168.0
HKD1_k127_6398440_36 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000002239 159.0
HKD1_k127_6398440_37 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.0000000000000000000000000000000000003657 147.0
HKD1_k127_6398440_38 seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing K05808 - - 0.000000000000000000000000000000000802 136.0
HKD1_k127_6398440_39 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000000564 106.0
HKD1_k127_6398440_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 613.0
HKD1_k127_6398440_40 EamA-like transporter family - - - 0.00000000000002369 74.0
HKD1_k127_6398440_41 - - - - 0.0001315 44.0
HKD1_k127_6398440_42 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0005063 50.0
HKD1_k127_6398440_5 binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 615.0
HKD1_k127_6398440_6 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 583.0
HKD1_k127_6398440_7 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 578.0
HKD1_k127_6398440_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 537.0
HKD1_k127_6398440_9 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 515.0
HKD1_k127_6402290_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 1.917e-273 866.0
HKD1_k127_6402290_1 rieske 2fe-2s K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 404.0
HKD1_k127_6402290_10 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000003063 104.0
HKD1_k127_6402290_11 LTXXQ motif family protein - - - 0.0000000000000001584 87.0
HKD1_k127_6402290_12 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00006142 47.0
HKD1_k127_6402290_13 - - - - 0.000541 51.0
HKD1_k127_6402290_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 402.0
HKD1_k127_6402290_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 389.0
HKD1_k127_6402290_4 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 342.0
HKD1_k127_6402290_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 314.0
HKD1_k127_6402290_6 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 321.0
HKD1_k127_6402290_7 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 297.0
HKD1_k127_6402290_8 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000003735 218.0
HKD1_k127_6402290_9 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000006007 149.0
HKD1_k127_6548491_0 acyl transferase domain K16128 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 548.0
HKD1_k127_6580658_0 PFAM extracellular solute-binding protein family 5 K12368 - - 3.123e-295 917.0
HKD1_k127_6580658_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 3.278e-238 746.0
HKD1_k127_6580658_10 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 344.0
HKD1_k127_6580658_11 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 254.0
HKD1_k127_6580658_12 Belongs to the ABC transporter superfamily K12371 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000009242 238.0
HKD1_k127_6580658_13 Belongs to the ABC transporter superfamily K12371 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000004857 241.0
HKD1_k127_6580658_14 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000002199 213.0
HKD1_k127_6580658_15 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000002874 161.0
HKD1_k127_6580658_16 Unextendable partial coding region - - - 0.000000000000006773 74.0
HKD1_k127_6580658_2 Penicillin amidase K01434 - 3.5.1.11 2.755e-226 726.0
HKD1_k127_6580658_3 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 557.0
HKD1_k127_6580658_4 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 542.0
HKD1_k127_6580658_5 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 544.0
HKD1_k127_6580658_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 492.0
HKD1_k127_6580658_7 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 484.0
HKD1_k127_6580658_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 456.0
HKD1_k127_6580658_9 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 450.0
HKD1_k127_6666672_0 COG0457 FOG TPR repeat - - - 2.053e-224 720.0
HKD1_k127_6666672_1 Major facilitator superfamily K03446,K18926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 389.0
HKD1_k127_6666672_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 376.0
HKD1_k127_6666672_3 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 364.0
HKD1_k127_6666672_4 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 376.0
HKD1_k127_6666672_5 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 301.0
HKD1_k127_6666672_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001208 276.0
HKD1_k127_6666672_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001216 244.0
HKD1_k127_6666672_8 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
HKD1_k127_6666672_9 helix_turn_helix, Lux Regulon - - - 0.00000000000005071 79.0
HKD1_k127_6733424_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 3.988e-242 756.0
HKD1_k127_6733424_1 Vault protein inter-alpha-trypsin domain - - - 2.976e-217 693.0
HKD1_k127_6733424_10 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 446.0
HKD1_k127_6733424_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 315.0
HKD1_k127_6733424_12 Transcriptional regulatory protein, C terminal K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002167 273.0
HKD1_k127_6733424_13 PFAM glycosyl transferase family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007684 260.0
HKD1_k127_6733424_14 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000000001234 213.0
HKD1_k127_6733424_15 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000001285 203.0
HKD1_k127_6733424_16 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000003575 201.0
HKD1_k127_6733424_17 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000001249 197.0
HKD1_k127_6733424_18 response regulator - - - 0.00000000000000000000000000000000000000000000000002286 187.0
HKD1_k127_6733424_19 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000585 191.0
HKD1_k127_6733424_2 ammonium transporter K03320 - - 9.956e-212 670.0
HKD1_k127_6733424_20 - - - - 0.000000000000000000000000000000000000000001977 163.0
HKD1_k127_6733424_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000002014 130.0
HKD1_k127_6733424_22 - - - - 0.00000000000000000006829 100.0
HKD1_k127_6733424_23 Membrane fusogenic activity K09806 - - 0.000000000000000002767 93.0
HKD1_k127_6733424_24 Domain of unknown function (DUF1840) - - - 0.0000000000000006154 87.0
HKD1_k127_6733424_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.583e-210 665.0
HKD1_k127_6733424_4 surface antigen variable number repeat protein K07001 - - 3.368e-201 650.0
HKD1_k127_6733424_5 Glutamate-cysteine ligase K01919 - 6.3.2.2 4.569e-201 636.0
HKD1_k127_6733424_6 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 591.0
HKD1_k127_6733424_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 577.0
HKD1_k127_6733424_8 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 504.0
HKD1_k127_6733424_9 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 506.0
HKD1_k127_6894819_0 oxidoreductase K04090 - 1.2.7.8 0.0 1639.0
HKD1_k127_6894819_1 Peptidase family M3 K01284 - 3.4.15.5 3.556e-252 797.0
HKD1_k127_6894819_10 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 483.0
HKD1_k127_6894819_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 443.0
HKD1_k127_6894819_12 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 434.0
HKD1_k127_6894819_13 PFAM aromatic amino acid K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 419.0
HKD1_k127_6894819_14 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 374.0
HKD1_k127_6894819_15 PFAM major facilitator superfamily MFS_1 K19577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 359.0
HKD1_k127_6894819_16 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 342.0
HKD1_k127_6894819_17 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
HKD1_k127_6894819_18 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 334.0
HKD1_k127_6894819_19 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 310.0
HKD1_k127_6894819_2 type II secretion system protein E K02454 - - 8.153e-207 666.0
HKD1_k127_6894819_20 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 310.0
HKD1_k127_6894819_21 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 299.0
HKD1_k127_6894819_22 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 302.0
HKD1_k127_6894819_23 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001309 288.0
HKD1_k127_6894819_24 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
HKD1_k127_6894819_25 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001829 239.0
HKD1_k127_6894819_26 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000002697 228.0
HKD1_k127_6894819_27 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000000000005743 216.0
HKD1_k127_6894819_28 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000001471 224.0
HKD1_k127_6894819_29 membrane - - - 0.000000000000000000000000000000000000000000000004752 176.0
HKD1_k127_6894819_3 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.945e-203 638.0
HKD1_k127_6894819_30 acetyltransferase - - - 0.00000000000000000000000000000000000000000002175 172.0
HKD1_k127_6894819_31 General Secretory Pathway K02463 - - 0.0000000000000000000000000000000000000000005035 167.0
HKD1_k127_6894819_32 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000005937 163.0
HKD1_k127_6894819_33 Lipocalin-like domain - - - 0.00000000000000000000000000319 117.0
HKD1_k127_6894819_34 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000003732 112.0
HKD1_k127_6894819_35 EF-hand domain - - - 0.0000000000000000000000009286 117.0
HKD1_k127_6894819_36 - - - - 0.000000000000000000000001523 112.0
HKD1_k127_6894819_37 General secretion pathway protein L K02461 - - 0.000000000000000000000008507 115.0
HKD1_k127_6894819_38 general secretion pathway protein K02457 - - 0.00000000000000000000003602 107.0
HKD1_k127_6894819_39 General secretion pathway protein I K02458 - - 0.00000000000000000001026 101.0
HKD1_k127_6894819_4 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 629.0
HKD1_k127_6894819_40 General secretion pathway K02462 - - 0.00000000000000000002182 104.0
HKD1_k127_6894819_41 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000004866 90.0
HKD1_k127_6894819_42 Protein of unknown function (DUF3108) - - - 0.000000000000000001487 99.0
HKD1_k127_6894819_43 general secretion pathway protein K02459 - - 0.00000000000000004328 94.0
HKD1_k127_6894819_44 general secretion pathway protein K02452 - - 0.0000001915 60.0
HKD1_k127_6894819_5 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 532.0
HKD1_k127_6894819_6 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 522.0
HKD1_k127_6894819_7 peptidase K01389,K01415,K07386 - 3.4.24.11,3.4.24.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 502.0
HKD1_k127_6894819_8 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 488.0
HKD1_k127_6894819_9 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 490.0
HKD1_k127_6901287_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1268.0
HKD1_k127_6901287_1 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 4.563e-237 740.0
HKD1_k127_6901287_10 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000001247 158.0
HKD1_k127_6901287_11 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000003243 138.0
HKD1_k127_6901287_12 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000003688 136.0
HKD1_k127_6901287_13 cytochrome K17230 - - 0.000000000000000000415 93.0
HKD1_k127_6901287_2 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 494.0
HKD1_k127_6901287_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 395.0
HKD1_k127_6901287_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 363.0
HKD1_k127_6901287_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009502 280.0
HKD1_k127_6901287_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007429 264.0
HKD1_k127_6901287_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000007496 216.0
HKD1_k127_6901287_8 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000003924 209.0
HKD1_k127_6901287_9 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000006337 177.0
HKD1_k127_6957880_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000001972 192.0
HKD1_k127_6957880_1 Transcriptional regulator, TraR DksA family - - - 0.0000000000000000000000000000000002828 143.0
HKD1_k127_6957880_2 Transposase - - - 0.00000000000000000000000002592 108.0
HKD1_k127_6957880_3 protein, contains PIN domain - - - 0.000000000000000000000001661 110.0
HKD1_k127_6957880_4 SpoVT / AbrB like domain - - - 0.00000000000002526 75.0
HKD1_k127_7077688_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1452.0
HKD1_k127_7077688_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 9.734e-250 784.0
HKD1_k127_7077688_10 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000004177 181.0
HKD1_k127_7077688_11 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.00000000000000000000000000000000008903 147.0
HKD1_k127_7077688_12 PIN domain - - - 0.000000000000000000000001898 110.0
HKD1_k127_7077688_13 SnoaL-like domain - - - 0.0000000000000000000001837 104.0
HKD1_k127_7077688_14 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000001608 100.0
HKD1_k127_7077688_15 3' exoribonuclease, RNase T-like - - - 0.000000169 63.0
HKD1_k127_7077688_16 PFAM GCN5-related N-acetyltransferase - - - 0.0000004408 51.0
HKD1_k127_7077688_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 4.999e-245 774.0
HKD1_k127_7077688_3 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 446.0
HKD1_k127_7077688_4 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 443.0
HKD1_k127_7077688_5 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 468.0
HKD1_k127_7077688_6 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 304.0
HKD1_k127_7077688_7 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002978 273.0
HKD1_k127_7077688_8 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000002924 187.0
HKD1_k127_7077688_9 Cupin domain - - - 0.000000000000000000000000000000000000000000000001073 179.0
HKD1_k127_7080269_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.642e-202 637.0
HKD1_k127_7080269_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000652 211.0
HKD1_k127_7080269_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000001911 166.0
HKD1_k127_7080269_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000566 96.0
HKD1_k127_7090361_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001568 283.0
HKD1_k127_7090361_1 FCD - - - 0.0000000000000000000000000000000000000000000000000000001415 196.0
HKD1_k127_7090361_2 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000216 151.0
HKD1_k127_7090361_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000001433 85.0
HKD1_k127_711169_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1138.0
HKD1_k127_711169_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1018.0
HKD1_k127_711169_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 438.0
HKD1_k127_711169_11 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 439.0
HKD1_k127_711169_12 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 427.0
HKD1_k127_711169_13 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 406.0
HKD1_k127_711169_14 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 410.0
HKD1_k127_711169_15 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 393.0
HKD1_k127_711169_16 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 391.0
HKD1_k127_711169_17 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 403.0
HKD1_k127_711169_18 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 369.0
HKD1_k127_711169_19 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 376.0
HKD1_k127_711169_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.929e-301 934.0
HKD1_k127_711169_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 336.0
HKD1_k127_711169_21 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 327.0
HKD1_k127_711169_22 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 316.0
HKD1_k127_711169_23 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 307.0
HKD1_k127_711169_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
HKD1_k127_711169_25 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001264 282.0
HKD1_k127_711169_26 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000001539 242.0
HKD1_k127_711169_27 Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000008482 243.0
HKD1_k127_711169_28 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
HKD1_k127_711169_29 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000005326 203.0
HKD1_k127_711169_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.412e-291 909.0
HKD1_k127_711169_30 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000000000000000000000000000006731 205.0
HKD1_k127_711169_31 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000001799 199.0
HKD1_k127_711169_32 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000005639 180.0
HKD1_k127_711169_33 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000003067 112.0
HKD1_k127_711169_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 3.011e-287 902.0
HKD1_k127_711169_5 ABC transporter C-terminal domain K06158 - - 9.638e-253 796.0
HKD1_k127_711169_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 544.0
HKD1_k127_711169_7 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 537.0
HKD1_k127_711169_8 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 458.0
HKD1_k127_711169_9 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 456.0
HKD1_k127_7124666_0 Multidrug ABC transporter permease K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 475.0
HKD1_k127_7124666_1 PFAM conserved K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 346.0
HKD1_k127_7124666_2 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000354 109.0
HKD1_k127_7124666_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000002522 73.0
HKD1_k127_7127918_0 TonB dependent receptor - - - 3.292e-208 675.0
HKD1_k127_7127918_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.000000000000000000000000000000000000000000002902 164.0
HKD1_k127_7181407_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.778e-243 773.0
HKD1_k127_7181407_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 453.0
HKD1_k127_7181407_11 Phosphopantetheine attachment site K02078 - - 0.000006251 51.0
HKD1_k127_7181407_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 441.0
HKD1_k127_7181407_3 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 383.0
HKD1_k127_7181407_4 Aerotolerance regulator N-terminal K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 325.0
HKD1_k127_7181407_5 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 303.0
HKD1_k127_7181407_6 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003831 254.0
HKD1_k127_7181407_7 pteridine-dependent deoxygenase - - - 0.00000000000000000000000000000000000000000006792 171.0
HKD1_k127_7183066_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 423.0
HKD1_k127_7183066_1 flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 319.0
HKD1_k127_7183589_0 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 601.0
HKD1_k127_7183589_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 511.0
HKD1_k127_7183589_10 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000205 158.0
HKD1_k127_7183589_11 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000001366 129.0
HKD1_k127_7183589_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 447.0
HKD1_k127_7183589_3 PFAM L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 361.0
HKD1_k127_7183589_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 323.0
HKD1_k127_7183589_5 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000009087 199.0
HKD1_k127_7183589_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000007705 199.0
HKD1_k127_7183589_7 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000000000006588 184.0
HKD1_k127_7183589_8 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000009367 196.0
HKD1_k127_7183589_9 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000007143 162.0
HKD1_k127_7189265_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.506e-307 951.0
HKD1_k127_7189265_1 Sodium:solute symporter family K14392 - - 9.475e-195 618.0
HKD1_k127_7189265_10 - - - - 0.000000000000000000000000000000000000000002021 171.0
HKD1_k127_7189265_11 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000004454 151.0
HKD1_k127_7189265_12 Dihaem cytochrome c - - - 0.0000000000000000000000000000000459 137.0
HKD1_k127_7189265_2 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 597.0
HKD1_k127_7189265_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 594.0
HKD1_k127_7189265_4 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 314.0
HKD1_k127_7189265_5 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000104 261.0
HKD1_k127_7189265_6 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004092 247.0
HKD1_k127_7189265_7 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000211 220.0
HKD1_k127_7189265_8 Complex I intermediate-associated protein 30 - - - 0.0000000000000000000000000000000000000000000000000000001249 200.0
HKD1_k127_7189265_9 Transcriptional regulator K03719 - - 0.00000000000000000000000000000000000000000000001442 196.0
HKD1_k127_7195033_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000007342 227.0
HKD1_k127_7211131_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1077.0
HKD1_k127_7211131_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.789e-286 895.0
HKD1_k127_7211131_10 PFAM extracellular solute-binding protein family 1 K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 540.0
HKD1_k127_7211131_11 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 517.0
HKD1_k127_7211131_12 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 518.0
HKD1_k127_7211131_13 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 496.0
HKD1_k127_7211131_14 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 443.0
HKD1_k127_7211131_15 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 438.0
HKD1_k127_7211131_16 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 439.0
HKD1_k127_7211131_17 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 424.0
HKD1_k127_7211131_18 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 425.0
HKD1_k127_7211131_19 PFAM glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 414.0
HKD1_k127_7211131_2 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 1.565e-208 672.0
HKD1_k127_7211131_20 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 406.0
HKD1_k127_7211131_21 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 392.0
HKD1_k127_7211131_22 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 382.0
HKD1_k127_7211131_23 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 381.0
HKD1_k127_7211131_24 Aldo keto K00011 - 1.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 360.0
HKD1_k127_7211131_25 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 350.0
HKD1_k127_7211131_26 binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 357.0
HKD1_k127_7211131_27 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 339.0
HKD1_k127_7211131_28 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
HKD1_k127_7211131_29 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 331.0
HKD1_k127_7211131_3 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 4.135e-208 657.0
HKD1_k127_7211131_30 Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005877 284.0
HKD1_k127_7211131_31 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 275.0
HKD1_k127_7211131_32 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005716 251.0
HKD1_k127_7211131_33 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
HKD1_k127_7211131_34 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007358 248.0
HKD1_k127_7211131_35 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001765 243.0
HKD1_k127_7211131_36 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003903 254.0
HKD1_k127_7211131_37 Peptidase M15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004685 244.0
HKD1_k127_7211131_38 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.0000000000000000000000000000000000000000000000000000000000000000005099 241.0
HKD1_k127_7211131_39 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000115 228.0
HKD1_k127_7211131_4 protein related to plant photosystem II stability assembly factor - - - 3.648e-202 647.0
HKD1_k127_7211131_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000009262 221.0
HKD1_k127_7211131_41 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000000001577 205.0
HKD1_k127_7211131_42 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000003463 203.0
HKD1_k127_7211131_43 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000003032 206.0
HKD1_k127_7211131_44 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000003861 191.0
HKD1_k127_7211131_45 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000313 190.0
HKD1_k127_7211131_46 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000006736 201.0
HKD1_k127_7211131_47 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000009747 165.0
HKD1_k127_7211131_48 transcriptional regulator - - - 0.0000000000000000000000000000000000000002433 172.0
HKD1_k127_7211131_49 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000000001366 145.0
HKD1_k127_7211131_5 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 4.042e-194 619.0
HKD1_k127_7211131_50 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.000000000000000000000000000001095 126.0
HKD1_k127_7211131_51 ThiS family K03636 - - 0.00000000000000000000000000001494 122.0
HKD1_k127_7211131_52 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.000000000000000000000000002263 114.0
HKD1_k127_7211131_53 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000004219 105.0
HKD1_k127_7211131_54 MarR family - - - 0.000000000000000002464 92.0
HKD1_k127_7211131_56 Domain of unknown function (DUF4440) - - - 0.00000000000002673 83.0
HKD1_k127_7211131_6 Dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 549.0
HKD1_k127_7211131_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 552.0
HKD1_k127_7211131_8 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 537.0
HKD1_k127_7211131_9 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 529.0
HKD1_k127_72201_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.381e-257 810.0
HKD1_k127_72201_1 Circularly permuted ATP-grasp type 2 - - - 3.295e-246 768.0
HKD1_k127_72201_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 306.0
HKD1_k127_72201_11 transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 302.0
HKD1_k127_72201_12 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 286.0
HKD1_k127_72201_13 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 293.0
HKD1_k127_72201_14 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 286.0
HKD1_k127_72201_15 COG0655 Multimeric flavodoxin WrbA - - - 0.000000000000000000000000000000000000000000000000000000002738 205.0
HKD1_k127_72201_16 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000001208 191.0
HKD1_k127_72201_17 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000002061 178.0
HKD1_k127_72201_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000001687 177.0
HKD1_k127_72201_19 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000002777 186.0
HKD1_k127_72201_2 DHH family K07462 - - 1.88e-219 695.0
HKD1_k127_72201_20 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000005302 159.0
HKD1_k127_72201_21 protein conserved in bacteria - - - 0.00000000000000000000002915 112.0
HKD1_k127_72201_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 623.0
HKD1_k127_72201_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 553.0
HKD1_k127_72201_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 563.0
HKD1_k127_72201_6 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 454.0
HKD1_k127_72201_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 396.0
HKD1_k127_72201_8 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 364.0
HKD1_k127_72201_9 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 354.0
HKD1_k127_7270376_0 Nitric oxide reductase large subunit K04561 - 1.7.2.5 0.0 1062.0
HKD1_k127_7270376_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 313.0
HKD1_k127_7270376_2 protein involved in response to NO K07234 - - 0.00007088 48.0
HKD1_k127_7307306_0 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 364.0
HKD1_k127_7307306_1 HAD-hyrolase-like K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 317.0
HKD1_k127_7307306_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000004454 215.0
HKD1_k127_7307306_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000005466 126.0
HKD1_k127_7321716_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1148.0
HKD1_k127_7321716_1 PFAM acyl-CoA dehydrogenase domain protein - - - 2.677e-278 866.0
HKD1_k127_7321716_10 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000007932 242.0
HKD1_k127_7321716_11 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
HKD1_k127_7321716_12 TraB family K09973 - - 0.00000000000000000000000000000000000000000001247 178.0
HKD1_k127_7321716_13 Membrane K15977 - - 0.00000000000000000000000000000000000000000001646 166.0
HKD1_k127_7321716_14 assembly chaperone K07346 - - 0.000000000000000000000001146 113.0
HKD1_k127_7321716_15 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000003996 81.0
HKD1_k127_7321716_16 Belongs to the ompA family K03286 - - 0.00000002829 63.0
HKD1_k127_7321716_17 Secreted protein - - - 0.00000006802 61.0
HKD1_k127_7321716_2 Acyl-CoA synthetase (NDP forming) K09181 - - 1.512e-249 799.0
HKD1_k127_7321716_3 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 452.0
HKD1_k127_7321716_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 439.0
HKD1_k127_7321716_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 301.0
HKD1_k127_7321716_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 291.0
HKD1_k127_7321716_7 outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001659 300.0
HKD1_k127_7321716_8 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 264.0
HKD1_k127_7321716_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001619 240.0
HKD1_k127_7408809_0 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 296.0
HKD1_k127_7408809_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005435 243.0
HKD1_k127_7408809_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000001066 116.0
HKD1_k127_7408809_3 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000001315 70.0
HKD1_k127_7478569_0 AMP-binding enzyme - - - 5.815e-242 757.0
HKD1_k127_7478569_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 474.0
HKD1_k127_7478569_2 EamA-like transporter family - - - 0.00000000000000002189 83.0
HKD1_k127_7485010_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1399.0
HKD1_k127_7485010_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 481.0
HKD1_k127_7485010_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 407.0
HKD1_k127_7485010_3 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 379.0
HKD1_k127_7485010_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000001649 244.0
HKD1_k127_7485010_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000002497 219.0
HKD1_k127_7485010_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000007957 69.0
HKD1_k127_7541225_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 5.932e-247 771.0
HKD1_k127_7552573_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1529.0
HKD1_k127_7552573_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0 1053.0
HKD1_k127_7552573_10 Zinc metalloprotease (Elastase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 413.0
HKD1_k127_7552573_11 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
HKD1_k127_7552573_12 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
HKD1_k127_7552573_13 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000512 250.0
HKD1_k127_7552573_14 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000001131 193.0
HKD1_k127_7552573_16 - - - - 0.00000000000000000000000000000000000002581 146.0
HKD1_k127_7552573_17 - - - - 0.00000000000000000000000000000000001168 140.0
HKD1_k127_7552573_18 T4-like virus tail tube protein gp19 - - - 0.000000001817 64.0
HKD1_k127_7552573_19 Major facilitator Superfamily - - - 0.00000003488 55.0
HKD1_k127_7552573_2 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 2.988e-249 775.0
HKD1_k127_7552573_20 - - - - 0.0000009266 59.0
HKD1_k127_7552573_3 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 5.166e-202 636.0
HKD1_k127_7552573_4 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 579.0
HKD1_k127_7552573_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 574.0
HKD1_k127_7552573_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 523.0
HKD1_k127_7552573_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 481.0
HKD1_k127_7552573_8 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 442.0
HKD1_k127_7552573_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 445.0
HKD1_k127_7721202_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 352.0
HKD1_k127_7721202_1 RNA polymerase sigma factor RpoS K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000005774 239.0
HKD1_k127_7721202_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000003774 233.0
HKD1_k127_7721202_3 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000000000000405 235.0
HKD1_k127_7721202_4 helix_turn_helix, mercury resistance - - - 0.0000000000000000004283 88.0
HKD1_k127_7729149_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1540.0
HKD1_k127_7729149_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 5.983e-289 908.0
HKD1_k127_7729149_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000721 234.0
HKD1_k127_7729149_12 Chaperone protein TorD - - - 0.00000000000000000000000000000003027 133.0
HKD1_k127_7729149_13 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000235 119.0
HKD1_k127_7729149_14 Protein of unknown function (DUF3306) - - - 0.0000000000000000000004333 105.0
HKD1_k127_7729149_15 Protein of unknown function (DUF3455) - - - 0.000000000000000000002256 102.0
HKD1_k127_7729149_2 4Fe-4S dicluster domain - - - 1.548e-226 721.0
HKD1_k127_7729149_3 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 582.0
HKD1_k127_7729149_4 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 582.0
HKD1_k127_7729149_5 PFAM regulatory protein, LysR K07219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 448.0
HKD1_k127_7729149_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
HKD1_k127_7729149_7 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 391.0
HKD1_k127_7729149_8 binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 328.0
HKD1_k127_7729149_9 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000007857 242.0
HKD1_k127_7765896_0 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 492.0
HKD1_k127_7765896_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 340.0
HKD1_k127_7899095_0 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 458.0
HKD1_k127_7899095_1 Alpha beta hydrolase - - - 0.000000000000000000000002584 112.0
HKD1_k127_7899095_2 Methyltransferase - - - 0.0000000006814 60.0
HKD1_k127_7899095_3 alpha/beta hydrolase fold - - - 0.00001578 52.0
HKD1_k127_790828_0 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 4.112e-312 981.0
HKD1_k127_790828_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.687e-309 954.0
HKD1_k127_790828_10 Cobalamin biosynthesis protein CobW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 509.0
HKD1_k127_790828_11 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 505.0
HKD1_k127_790828_12 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 496.0
HKD1_k127_790828_13 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 480.0
HKD1_k127_790828_14 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 447.0
HKD1_k127_790828_15 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 450.0
HKD1_k127_790828_16 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 433.0
HKD1_k127_790828_17 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 425.0
HKD1_k127_790828_18 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 421.0
HKD1_k127_790828_19 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 412.0
HKD1_k127_790828_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.315e-264 838.0
HKD1_k127_790828_20 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 413.0
HKD1_k127_790828_21 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 403.0
HKD1_k127_790828_22 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 397.0
HKD1_k127_790828_23 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 394.0
HKD1_k127_790828_24 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 394.0
HKD1_k127_790828_25 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 366.0
HKD1_k127_790828_26 Nad-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 354.0
HKD1_k127_790828_27 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 349.0
HKD1_k127_790828_28 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 343.0
HKD1_k127_790828_29 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
HKD1_k127_790828_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.63e-261 824.0
HKD1_k127_790828_30 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 321.0
HKD1_k127_790828_31 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 316.0
HKD1_k127_790828_32 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 308.0
HKD1_k127_790828_33 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 289.0
HKD1_k127_790828_34 acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 296.0
HKD1_k127_790828_35 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 261.0
HKD1_k127_790828_36 cytochrome C oxidase K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000207 254.0
HKD1_k127_790828_37 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002133 258.0
HKD1_k127_790828_38 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004998 271.0
HKD1_k127_790828_39 PFAM regulatory protein TetR K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003254 254.0
HKD1_k127_790828_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.312e-229 714.0
HKD1_k127_790828_40 Transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001759 258.0
HKD1_k127_790828_41 Electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000003288 239.0
HKD1_k127_790828_42 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000000000001424 251.0
HKD1_k127_790828_43 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000001148 239.0
HKD1_k127_790828_44 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000004659 228.0
HKD1_k127_790828_45 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000001556 226.0
HKD1_k127_790828_46 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000001089 215.0
HKD1_k127_790828_47 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000006279 214.0
HKD1_k127_790828_48 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000002104 213.0
HKD1_k127_790828_49 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000009496 203.0
HKD1_k127_790828_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.835e-205 645.0
HKD1_k127_790828_50 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000006926 191.0
HKD1_k127_790828_51 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000000000004749 192.0
HKD1_k127_790828_52 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000003391 190.0
HKD1_k127_790828_53 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000003877 192.0
HKD1_k127_790828_54 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000001092 183.0
HKD1_k127_790828_55 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000005864 190.0
HKD1_k127_790828_56 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000754 175.0
HKD1_k127_790828_57 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000003989 175.0
HKD1_k127_790828_58 Competence protein - - - 0.0000000000000000000000000000000000000000004589 166.0
HKD1_k127_790828_59 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000000007 161.0
HKD1_k127_790828_6 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 612.0
HKD1_k127_790828_60 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000003486 164.0
HKD1_k127_790828_61 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000001015 162.0
HKD1_k127_790828_62 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000009671 166.0
HKD1_k127_790828_63 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000234 155.0
HKD1_k127_790828_64 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000003644 147.0
HKD1_k127_790828_65 membrane K08972 - - 0.00000000000000000000000000000000000003386 147.0
HKD1_k127_790828_66 oxidoreductase, chain 4L K05560 - - 0.000000000000000000000000000000003486 142.0
HKD1_k127_790828_67 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000001024 127.0
HKD1_k127_790828_68 COG1320 Multisubunit Na H antiporter, MnhG subunit K05564 - - 0.00000000000000000000000000001393 126.0
HKD1_k127_790828_69 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000002537 117.0
HKD1_k127_790828_7 Soluble lytic murein K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 586.0
HKD1_k127_790828_70 TfoX N-terminal domain K07343 - - 0.000000000000000000000000005956 115.0
HKD1_k127_790828_71 PFAM multiple resistance and pH regulation protein F K05563 - - 0.000000000000000000000000008014 113.0
HKD1_k127_790828_72 PFAM Peptidase M23 - - - 0.00000000000000000000002271 112.0
HKD1_k127_790828_73 Protein of unknown function (DUF2970) - - - 0.0000000000000000001345 91.0
HKD1_k127_790828_74 Protein of unknown function (DUF2909) - - - 0.0000000000000000009571 98.0
HKD1_k127_790828_75 Protein of unknown function (DUF2905) - - - 0.000000000000000005426 90.0
HKD1_k127_790828_76 - - - - 0.00000000000000005374 87.0
HKD1_k127_790828_77 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000005436 64.0
HKD1_k127_790828_79 mercury ion transmembrane transporter activity - - - 0.00000386 51.0
HKD1_k127_790828_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 564.0
HKD1_k127_790828_80 - - - - 0.0000471 53.0
HKD1_k127_790828_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 516.0
HKD1_k127_912686_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1000.0
HKD1_k127_912686_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.624e-286 907.0
HKD1_k127_912686_10 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 416.0
HKD1_k127_912686_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 418.0
HKD1_k127_912686_12 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 398.0
HKD1_k127_912686_13 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 398.0
HKD1_k127_912686_14 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 396.0
HKD1_k127_912686_15 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 384.0
HKD1_k127_912686_16 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 377.0
HKD1_k127_912686_17 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 338.0
HKD1_k127_912686_18 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 343.0
HKD1_k127_912686_19 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 335.0
HKD1_k127_912686_2 deoxyribodipyrimidine photolyase-related protein K06876 - - 2.311e-236 741.0
HKD1_k127_912686_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 332.0
HKD1_k127_912686_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 315.0
HKD1_k127_912686_22 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004997 273.0
HKD1_k127_912686_23 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000008688 255.0
HKD1_k127_912686_24 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000006121 250.0
HKD1_k127_912686_25 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000137 256.0
HKD1_k127_912686_26 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
HKD1_k127_912686_27 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000268 209.0
HKD1_k127_912686_28 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000127 220.0
HKD1_k127_912686_29 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000003495 153.0
HKD1_k127_912686_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.685e-202 636.0
HKD1_k127_912686_30 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000004782 147.0
HKD1_k127_912686_31 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000001011 155.0
HKD1_k127_912686_32 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000004432 136.0
HKD1_k127_912686_33 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000005947 131.0
HKD1_k127_912686_34 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000002168 112.0
HKD1_k127_912686_35 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000003285 112.0
HKD1_k127_912686_36 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000005781 66.0
HKD1_k127_912686_4 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 591.0
HKD1_k127_912686_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 552.0
HKD1_k127_912686_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 509.0
HKD1_k127_912686_7 Na+ dependent nucleoside transporter C-terminus K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 443.0
HKD1_k127_912686_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 420.0
HKD1_k127_912686_9 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 415.0
HKD1_k127_925740_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.792e-290 915.0
HKD1_k127_925740_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 4.432e-255 796.0
HKD1_k127_925740_10 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 348.0
HKD1_k127_925740_11 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 334.0
HKD1_k127_925740_12 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 326.0
HKD1_k127_925740_13 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 315.0
HKD1_k127_925740_14 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 291.0
HKD1_k127_925740_15 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 286.0
HKD1_k127_925740_16 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000004005 273.0
HKD1_k127_925740_17 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
HKD1_k127_925740_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000001628 245.0
HKD1_k127_925740_19 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 248.0
HKD1_k127_925740_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 1.579e-206 652.0
HKD1_k127_925740_20 SpoU rRNA Methylase family K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000007032 242.0
HKD1_k127_925740_21 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002065 240.0
HKD1_k127_925740_22 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000005277 181.0
HKD1_k127_925740_23 peptidyl-prolyl K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000652 158.0
HKD1_k127_925740_24 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001013 155.0
HKD1_k127_925740_25 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000601 156.0
HKD1_k127_925740_26 MaoC like domain - - - 0.000000000000000000000000000000000003255 142.0
HKD1_k127_925740_27 - - - - 0.0000000006823 72.0
HKD1_k127_925740_29 - - - - 0.00002879 53.0
HKD1_k127_925740_3 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 1.591e-197 623.0
HKD1_k127_925740_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 529.0
HKD1_k127_925740_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 416.0
HKD1_k127_925740_6 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 382.0
HKD1_k127_925740_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 376.0
HKD1_k127_925740_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 357.0
HKD1_k127_925740_9 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 374.0
HKD1_k127_929133_0 synthetase K01895 - 6.2.1.1 3.024e-281 880.0
HKD1_k127_929133_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 2.816e-228 722.0
HKD1_k127_929133_10 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 457.0
HKD1_k127_929133_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 458.0
HKD1_k127_929133_12 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 428.0
HKD1_k127_929133_13 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 430.0
HKD1_k127_929133_14 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 404.0
HKD1_k127_929133_15 transcriptional Regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 347.0
HKD1_k127_929133_16 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 347.0
HKD1_k127_929133_17 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 346.0
HKD1_k127_929133_18 Pyridoxamine 5'-phosphate oxidase-related, FMN binding protein K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
HKD1_k127_929133_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 304.0
HKD1_k127_929133_2 flavoprotein involved in K transport - - - 5.043e-204 644.0
HKD1_k127_929133_20 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 297.0
HKD1_k127_929133_21 COG0477 Permeases of the major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004181 266.0
HKD1_k127_929133_22 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001025 253.0
HKD1_k127_929133_23 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000001141 232.0
HKD1_k127_929133_24 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000000000000000000000000000000000001404 213.0
HKD1_k127_929133_25 Protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000000000000006421 188.0
HKD1_k127_929133_26 Bacterial dnaA protein K10763 - - 0.00000000000000000000000000000000000000000000000001033 189.0
HKD1_k127_929133_27 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000006904 198.0
HKD1_k127_929133_28 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000004976 171.0
HKD1_k127_929133_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 4.959e-197 629.0
HKD1_k127_929133_30 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000002592 160.0
HKD1_k127_929133_31 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000001352 151.0
HKD1_k127_929133_32 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000000001477 136.0
HKD1_k127_929133_33 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.0000000000000000000000000000000001836 137.0
HKD1_k127_929133_34 FMN binding - - - 0.0000000000000000000000000000114 125.0
HKD1_k127_929133_35 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000009785 116.0
HKD1_k127_929133_36 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000000000000000004688 100.0
HKD1_k127_929133_37 Deoxynucleoside kinase - - - 0.000000000000000000004218 108.0
HKD1_k127_929133_38 Phosphopantetheine attachment site - - - 0.000000000000000005619 94.0
HKD1_k127_929133_39 Phosphopantetheine attachment site - - - 0.00000000000001108 81.0
HKD1_k127_929133_4 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 554.0
HKD1_k127_929133_40 WD-40 repeat - - - 0.000000000005613 78.0
HKD1_k127_929133_41 - - - - 0.00000000008673 70.0
HKD1_k127_929133_42 Bacterial PH domain - - - 0.00000002527 58.0
HKD1_k127_929133_44 extracellular matrix structural constituent - - - 0.0002535 50.0
HKD1_k127_929133_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 532.0
HKD1_k127_929133_6 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 517.0
HKD1_k127_929133_7 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 501.0
HKD1_k127_929133_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 480.0
HKD1_k127_929133_9 LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 468.0