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Overview

ID MAG01748
Name HKD1_bin.68
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Myxococcia
Order Myxococcales
Family Anaeromyxobacteraceae
Genus
Species
Assembly information
Completeness (%) 77.23
Contamination (%) 2.07
GC content (%) 74.0
N50 (bp) 3,688
Genome size (bp) 2,734,110

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2794

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1003919_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001854 273.0
HKD1_k127_1003919_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002778 228.0
HKD1_k127_1012497_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.362e-245 768.0
HKD1_k127_1012497_1 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 454.0
HKD1_k127_1012497_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 389.0
HKD1_k127_1012497_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001834 241.0
HKD1_k127_1012497_4 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000003482 215.0
HKD1_k127_1012497_5 PFAM Response regulator receiver domain K07684 - - 0.000000000000000000000000000000000000000000000000212 186.0
HKD1_k127_1012497_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000001598 172.0
HKD1_k127_1017824_0 - - - - 0.00000000000000000000000000002764 132.0
HKD1_k127_1024333_0 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 414.0
HKD1_k127_1024333_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 306.0
HKD1_k127_1024333_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 295.0
HKD1_k127_1024333_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 277.0
HKD1_k127_1024333_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001249 264.0
HKD1_k127_1024333_5 Belongs to the peptidase S11 family K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000003307 236.0
HKD1_k127_1024333_6 MlaD protein K06192 - - 0.000000000000000000000000000000000000001249 171.0
HKD1_k127_1024333_7 Protein of unknown function (DUF3617) - - - 0.000000000000000008928 95.0
HKD1_k127_1024333_8 Ion channel - - - 0.000000000000521 79.0
HKD1_k127_1025501_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001341 254.0
HKD1_k127_1025501_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000008778 98.0
HKD1_k127_102687_1 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 383.0
HKD1_k127_102687_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 376.0
HKD1_k127_102687_3 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000002351 207.0
HKD1_k127_1027174_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1343.0
HKD1_k127_1027174_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000128 74.0
HKD1_k127_1033197_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 291.0
HKD1_k127_1033197_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000006893 184.0
HKD1_k127_1033197_2 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000005088 125.0
HKD1_k127_1033197_3 EamA-like transporter family - - - 0.00000000000000001685 82.0
HKD1_k127_1044452_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 604.0
HKD1_k127_1044452_1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 563.0
HKD1_k127_1044452_2 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 540.0
HKD1_k127_1044452_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 325.0
HKD1_k127_1046187_0 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 381.0
HKD1_k127_1046187_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000000000000000000000000000000000000000000000000000000000000003283 219.0
HKD1_k127_1046187_2 Thaumatin family - - - 0.0000000000000000000000000000000000000000000002054 189.0
HKD1_k127_1061930_0 PFAM response regulator receiver K07713 - - 3.246e-225 714.0
HKD1_k127_1061930_1 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 537.0
HKD1_k127_1061930_2 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002287 256.0
HKD1_k127_1061930_3 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000000009453 203.0
HKD1_k127_1062409_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 291.0
HKD1_k127_1062409_1 translation initiation factor activity - - - 0.0000000000000000000000009059 119.0
HKD1_k127_1068256_0 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 480.0
HKD1_k127_1068256_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 441.0
HKD1_k127_1068256_2 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 309.0
HKD1_k127_1068256_3 metallopeptidase activity K06974 - - 0.00000000000000000000000000000000000000000000000000000000000000000004842 253.0
HKD1_k127_1068256_4 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000003728 178.0
HKD1_k127_1068256_6 EamA-like transporter family - - - 0.000000005622 67.0
HKD1_k127_1073926_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.037e-231 719.0
HKD1_k127_1073926_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000001136 248.0
HKD1_k127_107470_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 355.0
HKD1_k127_107470_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000008059 190.0
HKD1_k127_109187_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001077 286.0
HKD1_k127_109187_1 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000004739 198.0
HKD1_k127_109187_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000001567 139.0
HKD1_k127_1103966_0 Aerotolerance regulator N-terminal - - - 7.154e-239 781.0
HKD1_k127_1103966_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 440.0
HKD1_k127_1103966_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 423.0
HKD1_k127_1103966_3 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 308.0
HKD1_k127_1105518_0 ABC transporter K06020 - 3.6.3.25 3.624e-318 1015.0
HKD1_k127_1105518_1 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007412 284.0
HKD1_k127_1105518_2 KR domain - - - 0.00000000000000000000000000001081 122.0
HKD1_k127_1110288_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 5.973e-195 625.0
HKD1_k127_1135477_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 6.107e-220 689.0
HKD1_k127_1135477_1 Indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 601.0
HKD1_k127_1135477_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 400.0
HKD1_k127_1135477_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000005414 235.0
HKD1_k127_1135477_4 ACT domain - - - 0.000000000000000000000000000000000004901 158.0
HKD1_k127_1143818_0 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 476.0
HKD1_k127_1143818_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000004459 199.0
HKD1_k127_1147018_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 517.0
HKD1_k127_1147018_1 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 350.0
HKD1_k127_1147018_2 TonB C terminal K03646,K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000001538 231.0
HKD1_k127_1147018_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000002103 236.0
HKD1_k127_1147018_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000001821 203.0
HKD1_k127_1147018_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000001855 95.0
HKD1_k127_1148068_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 434.0
HKD1_k127_1148068_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 389.0
HKD1_k127_1148068_2 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 346.0
HKD1_k127_1148068_3 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000001032 81.0
HKD1_k127_1151559_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 521.0
HKD1_k127_1151559_1 Rhodanese Homology Domain - - - 0.00000000000000000000001338 117.0
HKD1_k127_1155568_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 371.0
HKD1_k127_1155568_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000009327 235.0
HKD1_k127_1155568_2 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
HKD1_k127_1159553_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 396.0
HKD1_k127_1159553_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 308.0
HKD1_k127_1159553_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 287.0
HKD1_k127_1159553_3 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006629 278.0
HKD1_k127_1159553_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005384 258.0
HKD1_k127_1159553_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000007253 186.0
HKD1_k127_1159553_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000001591 162.0
HKD1_k127_119627_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 569.0
HKD1_k127_119627_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 535.0
HKD1_k127_119627_10 transcription regulator, contains HTH domain (MarR family) - - - 0.000000000000000000000000000000000000000000000000001835 189.0
HKD1_k127_119627_11 - - - - 0.00000000000000000001803 97.0
HKD1_k127_119627_12 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000003526 80.0
HKD1_k127_119627_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 403.0
HKD1_k127_119627_3 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 361.0
HKD1_k127_119627_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 329.0
HKD1_k127_119627_5 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 273.0
HKD1_k127_119627_6 TIGRFAM urea amidolyase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001369 269.0
HKD1_k127_119627_7 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003219 265.0
HKD1_k127_119627_8 branched-chain amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003679 259.0
HKD1_k127_119627_9 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000000002159 240.0
HKD1_k127_119760_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 295.0
HKD1_k127_119760_1 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000001431 237.0
HKD1_k127_119760_2 Membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000003266 203.0
HKD1_k127_119760_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.0000000000000000000000000000000000006355 147.0
HKD1_k127_119760_4 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000009922 68.0
HKD1_k127_1203166_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.209e-310 964.0
HKD1_k127_1203495_0 Signal transduction histidine kinase - - - 8.87e-296 931.0
HKD1_k127_1203495_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 521.0
HKD1_k127_1203495_2 ATPase involved in DNA repair K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 439.0
HKD1_k127_1203495_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 357.0
HKD1_k127_1203495_4 nuclease activity K07460 - - 0.00000000000000000000000000000000000000000002177 165.0
HKD1_k127_1203495_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000004674 152.0
HKD1_k127_1203495_6 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000001678 109.0
HKD1_k127_1203495_7 Transglycosylase SLT domain K08309 - - 0.000000000493 66.0
HKD1_k127_1206495_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 401.0
HKD1_k127_1206495_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 355.0
HKD1_k127_1206495_2 domain protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
HKD1_k127_1206495_3 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000008018 129.0
HKD1_k127_1206495_4 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000006597 102.0
HKD1_k127_1206495_5 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000001049 103.0
HKD1_k127_1206495_6 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.00007461 51.0
HKD1_k127_1210265_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 385.0
HKD1_k127_1210265_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 295.0
HKD1_k127_1211580_0 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 362.0
HKD1_k127_1211580_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 318.0
HKD1_k127_1211580_2 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000008832 207.0
HKD1_k127_1211580_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000001786 191.0
HKD1_k127_1211580_4 Transcriptional regulatory protein, C terminal K07669 - - 0.00000000000000001106 96.0
HKD1_k127_1211858_0 bacterial-type flagellum-dependent cell motility K20951,K20952 - - 0.000000000000000000000000000000000001253 157.0
HKD1_k127_1223648_0 ErfK YbiS YcfS YnhG family protein K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 571.0
HKD1_k127_1223648_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 368.0
HKD1_k127_1223648_2 Protein of unknown function (DUF1059) - - - 0.0000009587 55.0
HKD1_k127_1233157_0 pseudouridine synthase activity K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 421.0
HKD1_k127_1233157_1 PFAM PHP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 308.0
HKD1_k127_1233157_3 - - - - 0.000000000000000000000000007012 113.0
HKD1_k127_1243224_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 501.0
HKD1_k127_1243224_1 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 464.0
HKD1_k127_1243224_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000454 268.0
HKD1_k127_1243224_3 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000001118 236.0
HKD1_k127_1243823_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 7.119e-233 746.0
HKD1_k127_1243823_1 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 380.0
HKD1_k127_1243823_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000153 276.0
HKD1_k127_1243823_3 8 heme-binding sites - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003816 284.0
HKD1_k127_1243823_5 Beta-lactamase - - - 0.00000000000000000000000000000000005328 155.0
HKD1_k127_1244357_0 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 538.0
HKD1_k127_1244357_1 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 507.0
HKD1_k127_1244357_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000001632 192.0
HKD1_k127_1262734_0 response regulator K07714 - - 1.113e-203 642.0
HKD1_k127_1262734_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 335.0
HKD1_k127_1262734_2 Helix-turn-helix XRE-family like proteins - - - 0.000000001351 61.0
HKD1_k127_1268902_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 8.781e-222 705.0
HKD1_k127_1268902_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 383.0
HKD1_k127_1268902_2 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 332.0
HKD1_k127_1268902_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0006856 52.0
HKD1_k127_1275522_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 494.0
HKD1_k127_1275522_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000006586 185.0
HKD1_k127_1275522_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000003305 178.0
HKD1_k127_1275946_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.04e-272 856.0
HKD1_k127_1275946_1 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.00000000000000000000000000001765 117.0
HKD1_k127_1297501_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 428.0
HKD1_k127_1297501_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 347.0
HKD1_k127_1297501_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008054 252.0
HKD1_k127_1297501_3 regulation of DNA repair K03565 - - 0.00000000000000000000000000000007551 128.0
HKD1_k127_1297501_4 Ami_3 K01448 - 3.5.1.28 0.0000008806 61.0
HKD1_k127_1302457_0 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 528.0
HKD1_k127_1302457_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 462.0
HKD1_k127_1302457_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 464.0
HKD1_k127_1302457_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000009296 134.0
HKD1_k127_1307226_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 535.0
HKD1_k127_1307226_1 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
HKD1_k127_1307226_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000657 279.0
HKD1_k127_1307226_3 regulator K07773 - - 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
HKD1_k127_1307226_4 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000002134 158.0
HKD1_k127_1307226_5 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000001275 94.0
HKD1_k127_1307226_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000001715 83.0
HKD1_k127_1307226_7 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000003574 80.0
HKD1_k127_1309859_1 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000176 99.0
HKD1_k127_1309859_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000007082 63.0
HKD1_k127_1311495_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 477.0
HKD1_k127_1311495_1 Uracil phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 406.0
HKD1_k127_1311495_2 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000001492 195.0
HKD1_k127_1311495_3 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000002614 173.0
HKD1_k127_1311495_4 Protein of unknown function (DUF3365) - - - 0.0000000000000006818 92.0
HKD1_k127_1322596_0 DEAD DEAH box helicase - - - 0.0 1291.0
HKD1_k127_1322596_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 524.0
HKD1_k127_1322596_2 OmpA family K03286 - - 0.0000000000000000000000000000000000000000000000003345 192.0
HKD1_k127_1325344_0 glutaminyl-tRNA K01886 - 6.1.1.18 1.687e-247 775.0
HKD1_k127_1325344_1 Dtw domain containing protein K05812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 276.0
HKD1_k127_1325344_2 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000006501 187.0
HKD1_k127_1325344_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000003188 169.0
HKD1_k127_1326651_0 Histidine kinase A domain protein K02482 - 2.7.13.3 3.344e-199 634.0
HKD1_k127_1326651_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 309.0
HKD1_k127_1326651_2 Belongs to the D-alanine--D-alanine ligase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 285.0
HKD1_k127_1326651_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000002837 183.0
HKD1_k127_132850_0 repeat protein - - - 0.0 1318.0
HKD1_k127_1339219_0 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 330.0
HKD1_k127_1339219_1 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000003438 236.0
HKD1_k127_1339219_2 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000007888 203.0
HKD1_k127_1339219_3 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000001124 202.0
HKD1_k127_1339219_4 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000005261 156.0
HKD1_k127_1339219_5 Cold shock protein K03704 - - 0.0000000000000000000000000000001131 126.0
HKD1_k127_1339219_6 cell redox homeostasis K03671 - - 0.0000000000000000003836 99.0
HKD1_k127_1339219_7 Protein of unknown function (DUF2892) - - - 0.0000000000000000006129 95.0
HKD1_k127_1366004_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 426.0
HKD1_k127_1366004_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 311.0
HKD1_k127_138433_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 481.0
HKD1_k127_138433_1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002828 248.0
HKD1_k127_138433_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000001056 76.0
HKD1_k127_1387353_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000001714 202.0
HKD1_k127_139040_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 3.663e-208 657.0
HKD1_k127_139040_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000005045 201.0
HKD1_k127_139040_2 OmpA family K03286 - - 0.000000000000000000000005992 115.0
HKD1_k127_1406930_0 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000000000000000000000000000000000000001064 181.0
HKD1_k127_1406930_1 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000005709 170.0
HKD1_k127_1406930_2 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000001852 115.0
HKD1_k127_1457765_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
HKD1_k127_1457765_1 Protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000002046 145.0
HKD1_k127_1465224_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 2.889e-212 677.0
HKD1_k127_1465224_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000002797 229.0
HKD1_k127_1465224_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000007266 125.0
HKD1_k127_1465922_0 PFAM Type II secretion system protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007695 256.0
HKD1_k127_1467281_0 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000005137 227.0
HKD1_k127_1467281_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000001172 135.0
HKD1_k127_1476178_0 Thioesterase superfamily - - - 0.0000000000000000000000000000000000006451 144.0
HKD1_k127_1476273_0 Pfam:DUF162 K00782 - - 0.00000000000000000000000000000000000000000000000000000008148 200.0
HKD1_k127_1476273_2 LUD domain - - - 0.0000000001593 73.0
HKD1_k127_1476273_3 Peptidase family M28 - - - 0.0000000006675 66.0
HKD1_k127_1479132_0 ABC transporter K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 452.0
HKD1_k127_1479132_1 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 411.0
HKD1_k127_1479132_2 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 325.0
HKD1_k127_1479132_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002654 276.0
HKD1_k127_1479132_4 PhoQ Sensor - - - 0.000000000000000003837 95.0
HKD1_k127_1502222_0 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 523.0
HKD1_k127_1502222_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 305.0
HKD1_k127_1502222_2 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000001252 137.0
HKD1_k127_1509709_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1307.0
HKD1_k127_1509709_1 Enoyl-(Acyl carrier protein) reductase K16066 - 1.1.1.381 0.0000000000000000000000000003659 114.0
HKD1_k127_1518611_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003053 273.0
HKD1_k127_1520430_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 444.0
HKD1_k127_1520430_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000007303 107.0
HKD1_k127_1547694_0 Participates in both transcription termination and antitermination K02600 - - 3.79e-307 957.0
HKD1_k127_1547694_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001076 267.0
HKD1_k127_1547694_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000005567 136.0
HKD1_k127_1547694_3 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.0000000000000000000021 96.0
HKD1_k127_1551997_0 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 346.0
HKD1_k127_1551997_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003465 278.0
HKD1_k127_1551997_2 Histidine kinase - - - 0.000000000000000000000000000000000000000003256 171.0
HKD1_k127_1551997_3 TPM domain - - - 0.00000000000000000000000000000000001536 143.0
HKD1_k127_1565635_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 552.0
HKD1_k127_1565635_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 432.0
HKD1_k127_1565635_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 334.0
HKD1_k127_1565635_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000000000000000000000000000000001795 156.0
HKD1_k127_1565635_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000878 56.0
HKD1_k127_1625925_0 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 372.0
HKD1_k127_1625925_1 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000000000000000000000001959 142.0
HKD1_k127_1625925_2 - - - - 0.0000000000000000007883 94.0
HKD1_k127_1625925_3 - - - - 0.000000000000001407 85.0
HKD1_k127_1631423_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 550.0
HKD1_k127_1631423_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000518 180.0
HKD1_k127_1648316_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000002957 202.0
HKD1_k127_1648316_1 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.0000126 58.0
HKD1_k127_1654825_0 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005883 246.0
HKD1_k127_1654825_1 Peptidase family M3 K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000000001918 177.0
HKD1_k127_1664969_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 513.0
HKD1_k127_1664969_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 417.0
HKD1_k127_1664969_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 345.0
HKD1_k127_1664969_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006788 285.0
HKD1_k127_1664969_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001484 229.0
HKD1_k127_1664999_0 4Fe-4S dicluster domain - - - 7.257e-320 990.0
HKD1_k127_1664999_3 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000001309 101.0
HKD1_k127_1665261_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 395.0
HKD1_k127_1665261_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 338.0
HKD1_k127_1666429_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.872e-195 619.0
HKD1_k127_1666429_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 440.0
HKD1_k127_1666429_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002691 280.0
HKD1_k127_1668224_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 350.0
HKD1_k127_1668224_1 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 309.0
HKD1_k127_1668224_2 - - - - 0.000000000000000000000002557 117.0
HKD1_k127_1668224_4 Elongation factor K02358 - - 0.00000005311 56.0
HKD1_k127_1670242_0 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 300.0
HKD1_k127_1670242_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001673 271.0
HKD1_k127_1670242_2 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000007631 242.0
HKD1_k127_1690769_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 376.0
HKD1_k127_1690769_1 ABC transporter K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000002067 156.0
HKD1_k127_1690769_2 - - - - 0.0000000000000000000001047 109.0
HKD1_k127_1690769_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000005414 103.0
HKD1_k127_1690769_4 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.000000000000000005588 96.0
HKD1_k127_169173_0 PAP2 superfamily C-terminal - - - 0.0000000000000000000000000000000000000006969 168.0
HKD1_k127_169173_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000008888 122.0
HKD1_k127_169173_3 lipid A biosynthetic process - - - 0.0000000000000000002145 94.0
HKD1_k127_169173_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000001274 95.0
HKD1_k127_169590_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 439.0
HKD1_k127_169590_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000001217 140.0
HKD1_k127_169590_2 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000002592 100.0
HKD1_k127_169757_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 3.804e-218 708.0
HKD1_k127_169757_1 Histidine kinase K07710,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 591.0
HKD1_k127_169757_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 337.0
HKD1_k127_169757_3 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000043 225.0
HKD1_k127_170604_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 370.0
HKD1_k127_170604_1 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 351.0
HKD1_k127_170604_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
HKD1_k127_170604_4 Regulatory protein, FmdB family - - - 0.00000000000000000000009631 104.0
HKD1_k127_1710623_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000008514 103.0
HKD1_k127_1710623_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000001787 91.0
HKD1_k127_1710623_2 outer membrane efflux protein K12340 - - 0.00001071 58.0
HKD1_k127_1734476_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 6.516e-320 988.0
HKD1_k127_1744480_0 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 474.0
HKD1_k127_1744480_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 369.0
HKD1_k127_1744480_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 311.0
HKD1_k127_1744480_3 PFAM glycosyl transferase family 25 K07270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007493 291.0
HKD1_k127_1744480_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000001401 219.0
HKD1_k127_1746556_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 553.0
HKD1_k127_1746556_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 331.0
HKD1_k127_1755154_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 467.0
HKD1_k127_1755154_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 307.0
HKD1_k127_1755154_2 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000111 264.0
HKD1_k127_1755154_3 cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000002316 220.0
HKD1_k127_1755154_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000004163 70.0
HKD1_k127_1772219_0 PFAM sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001477 277.0
HKD1_k127_1772219_1 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000001114 136.0
HKD1_k127_1772219_2 Thi4 family K00384 - 1.8.1.9 0.00000000000007439 73.0
HKD1_k127_1772219_3 Cupin 2, conserved barrel domain protein - - - 0.000000000004528 78.0
HKD1_k127_1772219_4 protein methyltransferase activity - - - 0.00000000003843 73.0
HKD1_k127_1772219_5 Cupin 2, conserved barrel domain protein - - - 0.00001882 57.0
HKD1_k127_177689_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 283.0
HKD1_k127_177689_1 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000001058 177.0
HKD1_k127_177689_3 Domain of unknown function (DUF4175) - - - 0.00000000000000000000003299 109.0
HKD1_k127_1784411_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 518.0
HKD1_k127_1784411_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000001352 126.0
HKD1_k127_1784411_2 Protein of unknown function (DUF4239) - - - 0.0000000000000000004525 98.0
HKD1_k127_1793107_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 458.0
HKD1_k127_1793107_1 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 334.0
HKD1_k127_1793107_2 Response regulator, receiver K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 289.0
HKD1_k127_1793107_3 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000001161 161.0
HKD1_k127_1793107_4 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000009095 117.0
HKD1_k127_1793107_5 Twin-arginine translocation pathway signal protein - - - 0.00000000004259 73.0
HKD1_k127_1795440_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 541.0
HKD1_k127_1795440_1 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 355.0
HKD1_k127_1795440_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 301.0
HKD1_k127_1795440_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000002831 253.0
HKD1_k127_1795440_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000006138 231.0
HKD1_k127_1795440_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000003037 90.0
HKD1_k127_1804555_0 PFAM Uncharacterised protein family (UPF0236) - - - 0.000000000000000000000000000000000000000000000005316 188.0
HKD1_k127_1805590_0 Aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 332.0
HKD1_k127_1806357_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.466e-212 683.0
HKD1_k127_1806357_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 517.0
HKD1_k127_1806357_2 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 296.0
HKD1_k127_1806357_3 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000007519 141.0
HKD1_k127_1806357_4 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000000000000005694 104.0
HKD1_k127_1806357_6 amine dehydrogenase activity - - - 0.00000003566 67.0
HKD1_k127_1813953_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004282 270.0
HKD1_k127_1813953_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000004636 236.0
HKD1_k127_1813953_2 Peptidase family M23 - - - 0.0000002353 59.0
HKD1_k127_1818070_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 483.0
HKD1_k127_1818070_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 329.0
HKD1_k127_1818070_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000005772 206.0
HKD1_k127_1818070_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000001848 151.0
HKD1_k127_18218_0 Nucleotidyl transferase K00978,K15669 - 2.7.7.33,2.7.7.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 396.0
HKD1_k127_18218_1 amine dehydrogenase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
HKD1_k127_18218_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 292.0
HKD1_k127_18218_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000009163 115.0
HKD1_k127_1824603_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
HKD1_k127_1837170_0 Major Facilitator Superfamily K08177 - - 8.275e-195 632.0
HKD1_k127_1837170_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 395.0
HKD1_k127_1837170_2 Molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 378.0
HKD1_k127_1845130_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.746e-261 817.0
HKD1_k127_1845130_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 642.0
HKD1_k127_1845130_10 ABC transporter C-terminal domain K06158 - - 0.00000000000204 79.0
HKD1_k127_1845130_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 410.0
HKD1_k127_1845130_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 400.0
HKD1_k127_1845130_4 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 384.0
HKD1_k127_1845130_5 PFAM ABC transporter K01990,K01992,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 352.0
HKD1_k127_1845130_6 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 329.0
HKD1_k127_1845130_7 PFAM Response regulator receiver domain K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 312.0
HKD1_k127_1845130_8 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 331.0
HKD1_k127_1845130_9 - - - - 0.0000000000004685 75.0
HKD1_k127_187040_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 492.0
HKD1_k127_187040_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 336.0
HKD1_k127_187040_2 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 285.0
HKD1_k127_1879112_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 385.0
HKD1_k127_1879112_1 domain, Protein K20276 - - 0.0000000000000000000000000000000000000000000000000009125 203.0
HKD1_k127_1896471_0 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 495.0
HKD1_k127_1901049_0 Mediates influx of magnesium ions K03284,K16074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 428.0
HKD1_k127_1901049_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 367.0
HKD1_k127_1901049_2 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.00000000000000000000000000000000000000001209 156.0
HKD1_k127_1901049_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000001424 77.0
HKD1_k127_1907283_0 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 452.0
HKD1_k127_1907283_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 304.0
HKD1_k127_1907283_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000002765 249.0
HKD1_k127_1907283_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000002228 156.0
HKD1_k127_1909650_0 - K06198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 347.0
HKD1_k127_1909650_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 330.0
HKD1_k127_1909650_2 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000006263 141.0
HKD1_k127_1921577_0 glutamate--cysteine ligase K01919 - 6.3.2.2 6.812e-200 631.0
HKD1_k127_1921577_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000001247 234.0
HKD1_k127_1921577_2 GAF domain - - - 0.00008683 54.0
HKD1_k127_1927144_0 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000001165 200.0
HKD1_k127_1927144_1 Histidine kinase - - - 0.0000000000000000002448 89.0
HKD1_k127_1935753_0 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 343.0
HKD1_k127_1935753_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000002061 246.0
HKD1_k127_1935753_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000008403 194.0
HKD1_k127_1935753_3 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000001552 180.0
HKD1_k127_1935753_4 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000001891 175.0
HKD1_k127_1935753_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000001195 186.0
HKD1_k127_1935753_6 PAS sensor protein - - - 0.00000000000000000000000000000000000000000000121 169.0
HKD1_k127_1935753_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000003482 146.0
HKD1_k127_1935753_8 peptide catabolic process K01256 - 3.4.11.2 0.000000000000000000000000000000000174 146.0
HKD1_k127_1935753_9 Peptidase MA superfamily - - - 0.000000000004283 79.0
HKD1_k127_1943287_0 Glycosyl transferase family 21 - - - 9.807e-232 727.0
HKD1_k127_1943287_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 306.0
HKD1_k127_1943287_2 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003948 261.0
HKD1_k127_1943287_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000001652 209.0
HKD1_k127_1943287_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000002698 140.0
HKD1_k127_1961011_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 389.0
HKD1_k127_1961011_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 367.0
HKD1_k127_1961011_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 356.0
HKD1_k127_1961011_3 Bacterial regulatory proteins, tetR family - - - 0.0004518 52.0
HKD1_k127_1987384_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1162.0
HKD1_k127_1987384_1 HAD-hyrolase-like K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000000005328 192.0
HKD1_k127_1987384_2 SMART Tetratricopeptide domain protein - - - 0.0000000001214 72.0
HKD1_k127_2030616_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 435.0
HKD1_k127_2030616_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 372.0
HKD1_k127_2030616_2 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 343.0
HKD1_k127_2030616_3 Alg9-like mannosyltransferase family K05286 - - 0.0000000000000000000000000000000000000000000000000007384 210.0
HKD1_k127_2032132_0 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 360.0
HKD1_k127_2032132_1 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 352.0
HKD1_k127_2032132_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 317.0
HKD1_k127_2032132_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 301.0
HKD1_k127_2032132_4 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 299.0
HKD1_k127_2032132_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000003569 120.0
HKD1_k127_2032951_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 327.0
HKD1_k127_2033858_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.435e-223 725.0
HKD1_k127_2033858_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 441.0
HKD1_k127_2033858_2 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 364.0
HKD1_k127_2033858_3 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 293.0
HKD1_k127_2033858_4 PAP2 superfamily C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000004482 246.0
HKD1_k127_2033858_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000001186 53.0
HKD1_k127_2033858_6 RND efflux system, outer membrane lipoprotein - - - 0.000002012 55.0
HKD1_k127_2034088_0 FeS assembly protein SufB K09014 - - 6.125e-271 854.0
HKD1_k127_2034088_1 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 372.0
HKD1_k127_2034088_2 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000001459 214.0
HKD1_k127_2034088_3 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000009188 157.0
HKD1_k127_2034088_5 abc transporter, permease K09015 - - 0.00001464 57.0
HKD1_k127_2034391_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 289.0
HKD1_k127_2034391_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000003538 107.0
HKD1_k127_2037194_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1202.0
HKD1_k127_2037194_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 345.0
HKD1_k127_2037194_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000107 172.0
HKD1_k127_2037254_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 302.0
HKD1_k127_2037254_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000005558 219.0
HKD1_k127_2037254_2 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000001899 170.0
HKD1_k127_2037254_3 Peptidoglycan-binding domain 1 protein - - - 0.00000000001888 74.0
HKD1_k127_2049586_0 Response regulator receiver K07713 - - 0.00000000000000000000000000000000000000000000000000000000004073 226.0
HKD1_k127_2049586_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000008737 161.0
HKD1_k127_2055539_0 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 441.0
HKD1_k127_2055539_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 305.0
HKD1_k127_2062155_0 4Fe-4S dicluster domain K18930 - - 0.0 1159.0
HKD1_k127_2062155_1 Histidine kinase internal region K02478,K07704 - 2.7.13.3 1.075e-246 772.0
HKD1_k127_2062155_2 response regulator K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001153 282.0
HKD1_k127_2062155_3 L-lactate permease K03303 - - 0.0000002482 55.0
HKD1_k127_206270_0 Peptidase family M3 K01392 - 3.4.24.15 6.658e-261 835.0
HKD1_k127_206270_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 457.0
HKD1_k127_206270_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000003355 175.0
HKD1_k127_206270_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000002976 172.0
HKD1_k127_2066847_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 492.0
HKD1_k127_2066847_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.0001429 53.0
HKD1_k127_2068838_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002721 257.0
HKD1_k127_2068838_1 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000003326 151.0
HKD1_k127_2072125_0 Transcriptional regulator - - - 3.634e-230 724.0
HKD1_k127_2072125_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.035e-207 655.0
HKD1_k127_2081103_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 329.0
HKD1_k127_2081103_1 Small-conductance mechanosensitive channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 322.0
HKD1_k127_2081103_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 254.0
HKD1_k127_2081103_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009027 255.0
HKD1_k127_2081103_5 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000003211 179.0
HKD1_k127_2081103_6 response to copper ion K16915 - - 0.00000000000000000001911 104.0
HKD1_k127_2082587_0 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 575.0
HKD1_k127_2082587_1 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 516.0
HKD1_k127_2082587_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 321.0
HKD1_k127_2082587_3 metalloendopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001399 267.0
HKD1_k127_2082587_4 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003322 235.0
HKD1_k127_2082587_5 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000002613 205.0
HKD1_k127_2082587_6 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001823 162.0
HKD1_k127_2087369_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 401.0
HKD1_k127_2105786_0 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 400.0
HKD1_k127_2105786_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 364.0
HKD1_k127_2105786_2 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001492 268.0
HKD1_k127_2105786_3 SnoaL-like domain - - - 0.000000000000000000000000000000449 130.0
HKD1_k127_2105786_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000004256 80.0
HKD1_k127_2111449_0 Putative metal-binding motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 459.0
HKD1_k127_2111449_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 330.0
HKD1_k127_2111449_2 protein import - - - 0.000000002175 61.0
HKD1_k127_2117728_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.003e-202 637.0
HKD1_k127_2117728_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000137 225.0
HKD1_k127_2117728_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.00000000000000000000000000000000000000000000002872 174.0
HKD1_k127_212922_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 612.0
HKD1_k127_212941_0 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 501.0
HKD1_k127_212941_1 - - - - 0.00000000000000000000000000000008418 136.0
HKD1_k127_212941_2 carboxylic ester hydrolase activity K18399 - - 0.0000000000000007537 92.0
HKD1_k127_2134013_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 3.109e-263 851.0
HKD1_k127_2134013_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 557.0
HKD1_k127_2134013_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.00001425 47.0
HKD1_k127_2163478_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 564.0
HKD1_k127_2172992_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 4.348e-227 713.0
HKD1_k127_2172992_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 6.308e-209 656.0
HKD1_k127_2172992_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 494.0
HKD1_k127_2174002_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 309.0
HKD1_k127_2174002_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000002248 191.0
HKD1_k127_2202302_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 467.0
HKD1_k127_2202302_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000001563 155.0
HKD1_k127_2202302_2 Peptidoglycan-binding domain 1 protein - - - 0.000000000000002531 81.0
HKD1_k127_2202302_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000699 71.0
HKD1_k127_2203209_0 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004616 243.0
HKD1_k127_2203209_1 - - - - 0.0000000000000000000000008586 111.0
HKD1_k127_2203209_2 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000151 82.0
HKD1_k127_2203658_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 585.0
HKD1_k127_2203658_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002369 278.0
HKD1_k127_2203658_2 - - - - 0.000000000000000000000000000000000000000000000000000002896 214.0
HKD1_k127_2203658_3 zinc-ribbon domain - - - 0.000000000000000000000000000003498 135.0
HKD1_k127_2203658_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000006595 70.0
HKD1_k127_2211839_0 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 467.0
HKD1_k127_2211839_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 444.0
HKD1_k127_2211839_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 391.0
HKD1_k127_2211839_3 Membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 347.0
HKD1_k127_2218297_0 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 535.0
HKD1_k127_2218297_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 406.0
HKD1_k127_2232795_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 457.0
HKD1_k127_2232795_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007614 278.0
HKD1_k127_2232795_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000268 228.0
HKD1_k127_2235078_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1175.0
HKD1_k127_2235078_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007104 259.0
HKD1_k127_2235078_2 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000000000000000000000000000000000000000000000000001681 220.0
HKD1_k127_225487_0 Male sterility protein K01897 - 6.2.1.3 0.0 1876.0
HKD1_k127_225487_1 Domain of unknown function (DUF2088) - - - 2.217e-288 891.0
HKD1_k127_225487_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 462.0
HKD1_k127_225487_3 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 386.0
HKD1_k127_225487_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 364.0
HKD1_k127_226341_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 321.0
HKD1_k127_226341_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008716 277.0
HKD1_k127_226341_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004399 262.0
HKD1_k127_2265301_0 DNA polymerase beta thumb K02347 - - 1.052e-223 738.0
HKD1_k127_2265301_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 507.0
HKD1_k127_2265301_2 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 383.0
HKD1_k127_2265301_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000005881 260.0
HKD1_k127_2272849_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 574.0
HKD1_k127_2272849_1 Protein of unknown function (DUF533) K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 357.0
HKD1_k127_2272849_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 364.0
HKD1_k127_2272849_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000005219 230.0
HKD1_k127_2285929_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 566.0
HKD1_k127_2285929_1 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000001479 178.0
HKD1_k127_2287799_0 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 436.0
HKD1_k127_2287799_1 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000000000000001953 220.0
HKD1_k127_2287799_2 PTS system K02795 - - 0.0000000000000000000000000000000000000000000000000000000009168 205.0
HKD1_k127_2287799_3 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000001737 136.0
HKD1_k127_2299332_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000005794 237.0
HKD1_k127_2299332_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000001287 199.0
HKD1_k127_2299332_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000003803 162.0
HKD1_k127_2299332_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000002234 52.0
HKD1_k127_2299413_0 SMART helicase c2 K03722 - 3.6.4.12 7.659e-291 914.0
HKD1_k127_2299413_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 578.0
HKD1_k127_2299413_2 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 329.0
HKD1_k127_2299413_3 Peptidase family M50 - - - 0.00000000000000001581 83.0
HKD1_k127_2313766_0 Cytochrome C assembly protein - - - 7.856e-271 848.0
HKD1_k127_2313766_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.283e-211 658.0
HKD1_k127_2313766_2 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 517.0
HKD1_k127_2313766_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001055 208.0
HKD1_k127_2318438_0 regulation of single-species biofilm formation K13572,K13573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 342.0
HKD1_k127_2318438_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 325.0
HKD1_k127_2318438_2 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 304.0
HKD1_k127_2318438_3 regulation of single-species biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000003026 246.0
HKD1_k127_2318438_5 Membrane transport protein K07088 - - 0.00000000000000000000000000000000001022 141.0
HKD1_k127_232041_0 Ser-tRNA(Ala) hydrolase activity K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 366.0
HKD1_k127_232041_1 AAA domain K10742 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 353.0
HKD1_k127_232041_2 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000006972 178.0
HKD1_k127_232041_3 Smr domain - - - 0.000000000000000000003675 107.0
HKD1_k127_232041_4 - - - - 0.0000001594 60.0
HKD1_k127_2327583_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 369.0
HKD1_k127_2327583_1 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 374.0
HKD1_k127_2341332_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 591.0
HKD1_k127_2341332_1 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005451 282.0
HKD1_k127_2341332_2 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000000000000000000000001063 224.0
HKD1_k127_2341332_3 pfam abc K01995 - - 0.00000000000002053 74.0
HKD1_k127_2361017_0 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 596.0
HKD1_k127_2361017_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 516.0
HKD1_k127_2361017_2 DNA polymerase K02337,K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 456.0
HKD1_k127_2361017_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000713 233.0
HKD1_k127_2374661_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.292e-237 742.0
HKD1_k127_2374661_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003506 291.0
HKD1_k127_2377177_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000001945 214.0
HKD1_k127_2377177_1 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000001065 124.0
HKD1_k127_2381446_0 Protein of unknown function (DUF2868) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 339.0
HKD1_k127_2381446_1 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000000000004651 140.0
HKD1_k127_2381446_2 Domain of unknown function (DUF3482) - - - 0.000000000000000000000001969 120.0
HKD1_k127_2401916_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 1.838e-258 809.0
HKD1_k127_2401916_1 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 561.0
HKD1_k127_2401916_2 Protein-disulfide isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 563.0
HKD1_k127_2401916_4 sulfur carrier activity - - - 0.00000000000000000000000006998 117.0
HKD1_k127_2413907_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 542.0
HKD1_k127_2413907_1 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 444.0
HKD1_k127_2419266_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000001864 188.0
HKD1_k127_2419266_1 Flagellar Assembly Protein A K09749 - - 0.0000004342 58.0
HKD1_k127_2428847_0 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 516.0
HKD1_k127_2428847_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 320.0
HKD1_k127_2441128_0 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 574.0
HKD1_k127_2441128_1 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000004683 261.0
HKD1_k127_2441128_2 Bacterial membrane protein, YfhO - - - 0.00001817 49.0
HKD1_k127_244878_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 324.0
HKD1_k127_244878_1 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000001152 173.0
HKD1_k127_244878_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000007465 175.0
HKD1_k127_244878_3 TPR repeat - - - 0.0000000000000000000000000000000002076 153.0
HKD1_k127_2453337_0 ABC-type branched-chain amino acid transport K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 336.0
HKD1_k127_2453337_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 342.0
HKD1_k127_2462929_0 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 392.0
HKD1_k127_246593_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.486e-278 905.0
HKD1_k127_246593_1 Acyl-CoA dehydrogenase, middle domain - - - 2.484e-195 627.0
HKD1_k127_246593_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 382.0
HKD1_k127_246593_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 351.0
HKD1_k127_2480440_0 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 492.0
HKD1_k127_2480440_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 396.0
HKD1_k127_2480440_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000112 264.0
HKD1_k127_2492088_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 470.0
HKD1_k127_2492088_1 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000001598 169.0
HKD1_k127_2494468_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 476.0
HKD1_k127_2494468_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 302.0
HKD1_k127_2494468_2 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000001979 215.0
HKD1_k127_2494468_3 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.00000000000000004241 83.0
HKD1_k127_2496738_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 506.0
HKD1_k127_2496738_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 367.0
HKD1_k127_2496738_3 Calcineurin-like phosphoesterase - - - 0.000000000000000522 89.0
HKD1_k127_250915_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000005275 127.0
HKD1_k127_250915_1 - K07283 - - 0.00000000000000000000003161 114.0
HKD1_k127_250915_2 Mechanosensitive ion channel - - - 0.00000003131 63.0
HKD1_k127_2511248_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 6.986e-249 773.0
HKD1_k127_2511248_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000005887 83.0
HKD1_k127_2516590_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 6.325e-249 772.0
HKD1_k127_2516590_1 imidazolonepropionase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 482.0
HKD1_k127_2516590_2 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000003288 205.0
HKD1_k127_2516590_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000005903 192.0
HKD1_k127_2529494_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 542.0
HKD1_k127_2529494_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 482.0
HKD1_k127_2529494_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 317.0
HKD1_k127_2546946_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.233e-280 872.0
HKD1_k127_2576058_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 9.27e-198 642.0
HKD1_k127_2576058_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 486.0
HKD1_k127_2576058_2 Sodium:solute symporter family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 349.0
HKD1_k127_2580121_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 431.0
HKD1_k127_2580121_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 352.0
HKD1_k127_2580121_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001798 241.0
HKD1_k127_2580121_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000314 192.0
HKD1_k127_2580121_4 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000005052 203.0
HKD1_k127_2591814_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 5.8e-209 659.0
HKD1_k127_2591814_1 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 572.0
HKD1_k127_2591814_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 398.0
HKD1_k127_2591814_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003769 275.0
HKD1_k127_2591814_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001496 275.0
HKD1_k127_2599601_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 328.0
HKD1_k127_2599601_1 Amidohydrolase family - - - 0.0000000000000000000001038 110.0
HKD1_k127_2599601_2 - - - - 0.0000000000000001436 80.0
HKD1_k127_2603259_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1025.0
HKD1_k127_2603259_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000867 113.0
HKD1_k127_2614514_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 612.0
HKD1_k127_2614514_1 Peptidase family M13 K01415,K07386 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 446.0
HKD1_k127_2616109_0 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 362.0
HKD1_k127_2616109_1 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 285.0
HKD1_k127_2616109_2 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000002417 199.0
HKD1_k127_2623807_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000002406 243.0
HKD1_k127_2624068_0 Universal stress protein family - - - 0.0000000000000000000000000000000000000134 153.0
HKD1_k127_2624068_1 DUF218 domain - - - 0.000000000000000000000000000000002292 143.0
HKD1_k127_2624068_2 Pfam:Methyltransf_26 - - - 0.000000000000000000000000004223 112.0
HKD1_k127_2624068_3 cheY-homologous receiver domain - - - 0.00000000000000007214 91.0
HKD1_k127_2624068_4 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000166 76.0
HKD1_k127_2634124_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 354.0
HKD1_k127_2634124_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000004571 239.0
HKD1_k127_2641057_0 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 574.0
HKD1_k127_2641057_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 547.0
HKD1_k127_2641057_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 489.0
HKD1_k127_2641057_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 458.0
HKD1_k127_2641057_4 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002144 271.0
HKD1_k127_2641057_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
HKD1_k127_2641057_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000001062 244.0
HKD1_k127_2645247_0 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 289.0
HKD1_k127_2645247_1 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000141 287.0
HKD1_k127_2645247_2 regulation of translation K05788 - - 0.00000000009453 63.0
HKD1_k127_2648158_0 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 310.0
HKD1_k127_2648158_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000001114 188.0
HKD1_k127_2648158_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000005248 113.0
HKD1_k127_2692396_0 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 366.0
HKD1_k127_2692396_1 response regulator K15012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
HKD1_k127_2692396_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004331 246.0
HKD1_k127_2692396_3 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000009978 123.0
HKD1_k127_2692894_0 PFAM Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 535.0
HKD1_k127_2692894_1 translation initiation factor activity K06996 - - 0.00001094 49.0
HKD1_k127_2718623_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.571e-257 801.0
HKD1_k127_2718623_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.182e-222 696.0
HKD1_k127_2718623_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000004702 182.0
HKD1_k127_2721743_0 ABC transporter, ATP-binding protein - - - 2.963e-276 856.0
HKD1_k127_2721743_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 410.0
HKD1_k127_2721743_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 303.0
HKD1_k127_2721743_3 Alternative locus ID - - - 0.0000000000000000002644 95.0
HKD1_k127_2722417_0 Type II and III secretion system protein K02453 - - 2.089e-264 835.0
HKD1_k127_272366_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 444.0
HKD1_k127_272366_1 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 299.0
HKD1_k127_2724627_0 daunorubicin resistance ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 371.0
HKD1_k127_2724627_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 386.0
HKD1_k127_2724627_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 342.0
HKD1_k127_2724627_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000003414 170.0
HKD1_k127_2724627_4 cytochrome oxidase assembly K02259 - - 0.000000000000000000000001204 115.0
HKD1_k127_2729338_0 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 437.0
HKD1_k127_2729338_1 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000003122 239.0
HKD1_k127_2729338_2 XdhC and CoxI family - - - 0.000000000000000000000000000000004217 132.0
HKD1_k127_2729338_3 Outer membrane efflux protein - - - 0.00000000000000000000001047 110.0
HKD1_k127_2729338_4 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.000000000000003392 87.0
HKD1_k127_2729338_5 Resolvase - - - 0.0002817 44.0
HKD1_k127_273336_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 374.0
HKD1_k127_273336_1 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 308.0
HKD1_k127_273336_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005075 265.0
HKD1_k127_273336_3 cobalamin binding K03496,K22491 - - 0.0000000000000000000000000000000000000000000000000000001149 205.0
HKD1_k127_273336_4 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000004575 176.0
HKD1_k127_273336_5 Complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000000000000001969 149.0
HKD1_k127_273336_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000001871 130.0
HKD1_k127_273336_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000001594 62.0
HKD1_k127_2737447_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 591.0
HKD1_k127_2737447_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 347.0
HKD1_k127_2737447_2 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000001759 171.0
HKD1_k127_2737447_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000295 69.0
HKD1_k127_2737967_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000001558 264.0
HKD1_k127_2737967_1 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
HKD1_k127_2737967_3 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000007846 92.0
HKD1_k127_2747357_0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001298 236.0
HKD1_k127_2747357_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001579 199.0
HKD1_k127_2747357_2 thiolester hydrolase activity K06889 - - 0.00000000000000000036 100.0
HKD1_k127_2750272_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 334.0
HKD1_k127_2750272_1 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 290.0
HKD1_k127_2750272_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000001024 224.0
HKD1_k127_2758438_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 5.895e-202 651.0
HKD1_k127_2758438_1 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 405.0
HKD1_k127_2758438_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000454 287.0
HKD1_k127_2767152_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 571.0
HKD1_k127_2767152_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002177 232.0
HKD1_k127_2767152_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000003592 140.0
HKD1_k127_277004_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 4.441e-226 723.0
HKD1_k127_277004_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 359.0
HKD1_k127_277004_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 300.0
HKD1_k127_2774673_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 382.0
HKD1_k127_2774673_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000279 217.0
HKD1_k127_2780619_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 329.0
HKD1_k127_2780619_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 329.0
HKD1_k127_2780619_2 FHA domain - - - 0.00000000000000000000000000000000000000000000000003712 188.0
HKD1_k127_278360_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 3.681e-238 743.0
HKD1_k127_278360_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000002748 103.0
HKD1_k127_2786714_0 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006667 283.0
HKD1_k127_2786927_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 439.0
HKD1_k127_2786927_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 356.0
HKD1_k127_2786927_2 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000002722 246.0
HKD1_k127_2786927_3 toxin biosynthetic process K03558 - - 0.0000001229 64.0
HKD1_k127_2799099_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.5e-323 994.0
HKD1_k127_2836954_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 609.0
HKD1_k127_2836954_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 464.0
HKD1_k127_2836954_2 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000001577 214.0
HKD1_k127_2836954_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000009019 117.0
HKD1_k127_2869872_0 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 487.0
HKD1_k127_2869872_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 367.0
HKD1_k127_2869872_2 Haem-degrading - - - 0.00000000000000000000000000000000000004751 149.0
HKD1_k127_2869872_3 TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000000002403 148.0
HKD1_k127_2907521_0 tRNA methyltransferase complex GCD14 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 267.0
HKD1_k127_2907521_1 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000007954 265.0
HKD1_k127_2907521_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000006059 220.0
HKD1_k127_2907521_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000000000000000001214 211.0
HKD1_k127_2907521_4 PFAM DoxX family protein - - - 0.00000000000000000000000000000000000000002735 169.0
HKD1_k127_291581_0 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 362.0
HKD1_k127_291581_1 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000002904 187.0
HKD1_k127_291581_2 Belongs to the DegT DnrJ EryC1 family K19715 - 2.6.1.109 0.000000000000000000000000001419 113.0
HKD1_k127_291845_0 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 317.0
HKD1_k127_291845_1 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000002591 176.0
HKD1_k127_291845_2 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000000000000002204 129.0
HKD1_k127_291845_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.00000000000000000003474 92.0
HKD1_k127_2919398_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.26e-316 980.0
HKD1_k127_2919398_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 454.0
HKD1_k127_2919398_2 Belongs to the glutaminase family K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 409.0
HKD1_k127_2919398_3 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000002007 128.0
HKD1_k127_2919398_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000125 61.0
HKD1_k127_2946701_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit, BcrC BadD HgdB K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000002392 196.0
HKD1_k127_2946701_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000001956 201.0
HKD1_k127_2952453_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 471.0
HKD1_k127_2952453_1 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000002395 164.0
HKD1_k127_2971985_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 405.0
HKD1_k127_2971985_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000003799 171.0
HKD1_k127_2989952_0 Tetratricopeptide repeat - - - 3.551e-258 831.0
HKD1_k127_2989952_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 450.0
HKD1_k127_2989952_2 nuclear chromosome segregation K02557,K03497 - - 0.00000000000000000000000000000002943 144.0
HKD1_k127_2992574_0 sporulation resulting in formation of a cellular spore K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003414 279.0
HKD1_k127_2992574_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000009116 147.0
HKD1_k127_3008729_0 Transglycosylase-like domain K21687 - - 0.00000000000000000000000000000000000000000000000000004515 201.0
HKD1_k127_3008729_1 fructose-bisphosphate aldolase K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 0.0000000008812 59.0
HKD1_k127_3019273_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 631.0
HKD1_k127_3019273_1 Cysteine rich repeat K06816 - - 0.00000000000002031 86.0
HKD1_k127_3019273_2 - - - - 0.0000000002599 63.0
HKD1_k127_3019273_3 - - - - 0.000000007952 59.0
HKD1_k127_3029323_0 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 424.0
HKD1_k127_3029323_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 300.0
HKD1_k127_3029323_2 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000005814 218.0
HKD1_k127_3029323_3 protein trimerization - - - 0.000000006063 62.0
HKD1_k127_3031_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 334.0
HKD1_k127_3031_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000000000000000000000000005411 159.0
HKD1_k127_3031_2 Adenylate cyclase - - - 0.00000000000006425 81.0
HKD1_k127_3031857_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 445.0
HKD1_k127_3031857_1 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 398.0
HKD1_k127_3031857_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 403.0
HKD1_k127_3031857_3 Adenylylsulfate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000003149 198.0
HKD1_k127_3031857_4 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000338 182.0
HKD1_k127_3031857_5 - - - - 0.00000000000000000000000000000000004397 154.0
HKD1_k127_3031857_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000002203 57.0
HKD1_k127_3036093_0 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 426.0
HKD1_k127_3036093_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 293.0
HKD1_k127_3036093_2 - - - - 0.00000000000000000003176 94.0
HKD1_k127_3036093_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000008131 96.0
HKD1_k127_3041367_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 514.0
HKD1_k127_3041367_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 337.0
HKD1_k127_3041367_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000000000001827 224.0
HKD1_k127_3041367_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000005193 191.0
HKD1_k127_3041367_4 NADH flavin oxidoreductase NADH oxidase K22347 - 1.8.1.20 0.0000000000000000000000001888 120.0
HKD1_k127_3044099_0 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 318.0
HKD1_k127_3044099_1 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000148 131.0
HKD1_k127_3044099_2 Redoxin K03564 - 1.11.1.15 0.000000000000000000004099 93.0
HKD1_k127_3044650_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 550.0
HKD1_k127_3044650_1 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 394.0
HKD1_k127_3044650_2 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000000000000000000000001382 204.0
HKD1_k127_3044650_3 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000657 187.0
HKD1_k127_3044650_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000002806 121.0
HKD1_k127_3044650_5 - - - - 0.0000005358 58.0
HKD1_k127_3047501_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.922e-242 758.0
HKD1_k127_3047501_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001707 287.0
HKD1_k127_3047501_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000557 276.0
HKD1_k127_3047501_3 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002259 249.0
HKD1_k127_3047501_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000002043 196.0
HKD1_k127_3049561_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.972e-316 972.0
HKD1_k127_3053559_0 DNA helicase K03656,K03657 - 3.6.4.12 7.755e-268 843.0
HKD1_k127_3053559_1 Type II/IV secretion system protein K02669 - - 6.339e-219 684.0
HKD1_k127_3053559_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002164 232.0
HKD1_k127_3053559_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000001037 221.0
HKD1_k127_3053559_4 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
HKD1_k127_3053559_5 iron ion binding - - - 0.000000000000000000000000000000000000000000000000006999 189.0
HKD1_k127_305375_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 570.0
HKD1_k127_305375_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001681 279.0
HKD1_k127_305375_3 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000002235 135.0
HKD1_k127_305522_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 4.344e-232 732.0
HKD1_k127_305522_1 General secretion pathway protein F K02455,K02653 - - 0.0000000000001539 71.0
HKD1_k127_3058072_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000001457 233.0
HKD1_k127_3058072_1 chemotaxis K03408 - - 0.00000000000000000000000000000000000000000002101 172.0
HKD1_k127_3058072_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000003126 172.0
HKD1_k127_3061331_0 CoA binding domain K09181 - - 8.438e-302 950.0
HKD1_k127_3061331_1 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 3.053e-225 709.0
HKD1_k127_3061331_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 410.0
HKD1_k127_3061331_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 377.0
HKD1_k127_3061331_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 334.0
HKD1_k127_3061331_5 response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 353.0
HKD1_k127_3061331_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 334.0
HKD1_k127_3061331_7 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001338 282.0
HKD1_k127_3061331_8 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000000000000006855 181.0
HKD1_k127_3061331_9 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000005515 165.0
HKD1_k127_3066277_0 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 542.0
HKD1_k127_3066277_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 420.0
HKD1_k127_3066277_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 380.0
HKD1_k127_3066277_3 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000007881 199.0
HKD1_k127_3068954_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1124.0
HKD1_k127_3072938_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 554.0
HKD1_k127_3072938_1 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 302.0
HKD1_k127_3072938_2 ATP synthesis coupled proton transport K02109 - - 0.000000000000000000000000000000000000000000000000000000000004296 214.0
HKD1_k127_3072938_3 - - - - 0.00000000000000000000000000000000000000000428 166.0
HKD1_k127_3072938_4 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000001968 113.0
HKD1_k127_3072938_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000001652 56.0
HKD1_k127_3072938_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00001288 48.0
HKD1_k127_3099173_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 599.0
HKD1_k127_3099173_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 453.0
HKD1_k127_3099173_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003858 296.0
HKD1_k127_3099173_3 spore germination K15270 - - 0.0000000000000000000000000000000000000000000000000000000001226 209.0
HKD1_k127_3099173_4 - - - - 0.00000000000000000000000000000000000000000000000000001535 193.0
HKD1_k127_3099173_5 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000000534 148.0
HKD1_k127_3099173_6 Protein of unknown function (DUF4019) - - - 0.00000000000000000009825 98.0
HKD1_k127_3102502_0 heat shock protein 70 K04043 - - 2.596e-211 664.0
HKD1_k127_3102502_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 449.0
HKD1_k127_3102502_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001895 277.0
HKD1_k127_3102502_3 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000001867 245.0
HKD1_k127_3102502_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000006081 256.0
HKD1_k127_3112717_0 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 575.0
HKD1_k127_3112717_1 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 418.0
HKD1_k127_3137875_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179 - 1.2.7.8 0.0 1234.0
HKD1_k127_3137875_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 2.056e-257 810.0
HKD1_k127_3137875_2 Belongs to the thiolase family K07508 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 611.0
HKD1_k127_3137875_3 Enoyl-CoA hydratase/isomerase K16427 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042802,GO:0051213,GO:0055114 1.13.11.80 0.00000000000000000000000000000000000000000000000008977 205.0
HKD1_k127_3144363_0 DNA helicase K03657 - 3.6.4.12 0.0 1074.0
HKD1_k127_3144363_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.678e-226 715.0
HKD1_k127_3144363_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 4.414e-217 686.0
HKD1_k127_3144363_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000006981 242.0
HKD1_k127_3144363_4 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000128 258.0
HKD1_k127_3144363_5 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000008688 227.0
HKD1_k127_3144363_6 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000001984 175.0
HKD1_k127_3144363_7 TM2 domain - - - 0.0000000000000000000000000001068 136.0
HKD1_k127_314557_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000002007 206.0
HKD1_k127_314557_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000001183 119.0
HKD1_k127_314557_2 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000009207 98.0
HKD1_k127_3155087_0 chaperone-mediated protein folding K21007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 411.0
HKD1_k127_3155087_1 Aldo keto reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000008749 257.0
HKD1_k127_318329_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.497e-238 742.0
HKD1_k127_318329_1 Cys Met metabolism K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 584.0
HKD1_k127_318329_2 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 465.0
HKD1_k127_318329_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000001212 247.0
HKD1_k127_3188936_0 OmpA family - - - 0.0000000000000000000000000000000000000000000000000003862 193.0
HKD1_k127_3188936_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000001875 171.0
HKD1_k127_3188936_2 - - - - 0.000000000000000000000000001196 129.0
HKD1_k127_3188936_3 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0001739 50.0
HKD1_k127_3189507_0 Tetratricopeptide repeats - - - 4.65e-196 642.0
HKD1_k127_3189507_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 537.0
HKD1_k127_3189507_2 AAA domain - - - 0.00008509 44.0
HKD1_k127_3193346_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 453.0
HKD1_k127_3193346_1 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 317.0
HKD1_k127_3193346_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000004038 218.0
HKD1_k127_3195723_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 586.0
HKD1_k127_3196161_0 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 494.0
HKD1_k127_3196161_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 409.0
HKD1_k127_3196161_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000003935 82.0
HKD1_k127_3208597_0 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000005502 220.0
HKD1_k127_3208597_1 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000132 189.0
HKD1_k127_3208597_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000001747 112.0
HKD1_k127_3208597_3 Copper binding periplasmic protein CusF - - - 0.00000000000000000000006408 110.0
HKD1_k127_3209616_0 Heat shock protein DnaJ domain protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 392.0
HKD1_k127_3209616_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 333.0
HKD1_k127_3209616_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000004989 99.0
HKD1_k127_3209616_3 - - - - 0.00000000000000000004177 94.0
HKD1_k127_3214433_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 494.0
HKD1_k127_3214433_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000005363 236.0
HKD1_k127_3235719_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 428.0
HKD1_k127_3235719_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 337.0
HKD1_k127_3235719_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000001852 130.0
HKD1_k127_323627_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 499.0
HKD1_k127_323627_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000006075 233.0
HKD1_k127_323966_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 552.0
HKD1_k127_323966_1 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 384.0
HKD1_k127_323966_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008528 268.0
HKD1_k127_323966_3 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000004831 194.0
HKD1_k127_323966_4 - - - - 0.0002234 50.0
HKD1_k127_3239663_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 396.0
HKD1_k127_3239663_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004458 277.0
HKD1_k127_3239663_2 Methyl-transferase K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000001774 198.0
HKD1_k127_3239663_3 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000009307 115.0
HKD1_k127_3239663_5 diguanylate cyclase - - - 0.000000007705 61.0
HKD1_k127_3239663_6 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000003716 51.0
HKD1_k127_3241513_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 531.0
HKD1_k127_3241513_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 527.0
HKD1_k127_3241513_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 509.0
HKD1_k127_3241513_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000001022 97.0
HKD1_k127_3248512_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 508.0
HKD1_k127_3248512_1 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000001724 198.0
HKD1_k127_3248512_2 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000002991 147.0
HKD1_k127_3252640_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 401.0
HKD1_k127_3252640_1 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 312.0
HKD1_k127_3259393_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 379.0
HKD1_k127_3259393_1 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 355.0
HKD1_k127_3259393_2 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003051 294.0
HKD1_k127_3259393_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000003923 121.0
HKD1_k127_3259393_4 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000005016 108.0
HKD1_k127_3259950_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1133.0
HKD1_k127_3259950_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001008 153.0
HKD1_k127_3270916_0 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000788 144.0
HKD1_k127_3270916_1 - - - - 0.000000000000000000000000001979 114.0
HKD1_k127_3277771_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 604.0
HKD1_k127_3277771_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 496.0
HKD1_k127_3277771_2 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000005698 211.0
HKD1_k127_3279821_0 UPF0313 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 570.0
HKD1_k127_3279821_1 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 582.0
HKD1_k127_3279821_2 domain, Protein - - - 0.000000000000000000000000000000000001215 153.0
HKD1_k127_3279821_3 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000008619 147.0
HKD1_k127_3279821_5 - - - - 0.000001946 57.0
HKD1_k127_3283510_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 502.0
HKD1_k127_3283510_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000001097 258.0
HKD1_k127_3295134_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 514.0
HKD1_k127_3295134_1 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 477.0
HKD1_k127_3295134_2 Protoglobin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 458.0
HKD1_k127_3295134_3 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 386.0
HKD1_k127_3295134_4 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 322.0
HKD1_k127_3295134_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000005062 174.0
HKD1_k127_3295134_6 mttA/Hcf106 family K03116 - - 0.00000000000004984 74.0
HKD1_k127_330092_0 Stage II sporulation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 535.0
HKD1_k127_330092_1 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 536.0
HKD1_k127_330092_2 Rhodanese Homology Domain - - - 0.000000000000000000000000002041 130.0
HKD1_k127_3301305_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000002845 251.0
HKD1_k127_3301305_1 TonB C terminal K03646 - - 0.000000000000000000000000000000000000000000000000000000001081 213.0
HKD1_k127_3301305_2 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000002162 124.0
HKD1_k127_3303863_0 PFAM Glycosyl transferase family 2 K00752,K11936 - 2.4.1.212 2.524e-202 636.0
HKD1_k127_3303863_1 Polysaccharide deacetylase K11931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 494.0
HKD1_k127_3303863_2 PgaD-like protein K11937 - - 0.000000000000000000000000000002076 126.0
HKD1_k127_3305340_0 twitching motility protein K02669 - - 4.134e-199 634.0
HKD1_k127_3305340_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 350.0
HKD1_k127_3305340_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 281.0
HKD1_k127_3306027_0 FtsX-like permease family - - - 5.407e-210 669.0
HKD1_k127_3306027_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 516.0
HKD1_k127_3306027_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000005076 187.0
HKD1_k127_3311485_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 529.0
HKD1_k127_3311485_1 protein conserved in bacteria K09799 - - 0.000000000000000000000000000000000000000000000000000000004101 203.0
HKD1_k127_3311485_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000009864 124.0
HKD1_k127_332132_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 483.0
HKD1_k127_332132_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 378.0
HKD1_k127_332132_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 328.0
HKD1_k127_332132_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000001682 259.0
HKD1_k127_3329391_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000002862 152.0
HKD1_k127_3329391_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000001979 65.0
HKD1_k127_333144_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 382.0
HKD1_k127_333144_1 twin-arginine translocation pathway signal protein - - - 0.00008896 51.0
HKD1_k127_3332_0 COG0436 Aspartate tyrosine aromatic aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 565.0
HKD1_k127_3332_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 425.0
HKD1_k127_3332_2 - - - - 0.000000000000000000000000000000000000000000000000000002645 210.0
HKD1_k127_3332_3 Dienelactone hydrolase family - - - 0.0000000000000000000000002044 121.0
HKD1_k127_3357984_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000857 261.0
HKD1_k127_3357984_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001024 250.0
HKD1_k127_3357984_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000126 156.0
HKD1_k127_3373879_0 Histidine kinase HAMP - - - 3.892e-206 655.0
HKD1_k127_3373879_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 451.0
HKD1_k127_3373879_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 345.0
HKD1_k127_3373879_3 B12 binding domain K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 299.0
HKD1_k127_3373879_4 helix_turn_helix, Lux Regulon - - - 0.000000006571 56.0
HKD1_k127_3379594_0 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000001177 198.0
HKD1_k127_3379594_1 chaperone-mediated protein folding K21007 - - 0.0000000000000000000000000000000000000000000000001013 185.0
HKD1_k127_3425085_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.516e-287 888.0
HKD1_k127_3425085_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 343.0
HKD1_k127_3425085_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 334.0
HKD1_k127_3425085_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000004212 287.0
HKD1_k127_3425085_4 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000002482 184.0
HKD1_k127_3425085_5 - - - - 0.000000000000000000000000000007213 133.0
HKD1_k127_3425085_6 Transglycosylase K08309 - - 0.0000008508 62.0
HKD1_k127_3448262_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000001698 232.0
HKD1_k127_3456911_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000953 249.0
HKD1_k127_3456911_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000006665 139.0
HKD1_k127_345787_0 Malate synthase K01638 - 2.3.3.9 0.0 1223.0
HKD1_k127_345787_1 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 456.0
HKD1_k127_345787_2 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 457.0
HKD1_k127_345787_3 - - - - 0.00000000000000000000000000000000000003208 148.0
HKD1_k127_346371_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 464.0
HKD1_k127_346371_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000001827 99.0
HKD1_k127_346371_2 Diguanylate cyclase, GGDEF domain - - - 0.00008979 50.0
HKD1_k127_3487676_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000000004007 241.0
HKD1_k127_3487676_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000004088 131.0
HKD1_k127_3487676_3 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.0000000000000000001163 104.0
HKD1_k127_3500684_0 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 388.0
HKD1_k127_3500684_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.00000000000000000000000000000000000000000000000001037 187.0
HKD1_k127_3500684_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000003283 79.0
HKD1_k127_3500684_3 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000004133 66.0
HKD1_k127_3506597_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 312.0
HKD1_k127_3506597_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000001843 147.0
HKD1_k127_3506597_3 - - - - 0.00007174 55.0
HKD1_k127_3512172_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 6.996e-286 884.0
HKD1_k127_3512172_1 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008219 258.0
HKD1_k127_3512172_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000009464 131.0
HKD1_k127_3513658_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.17e-320 989.0
HKD1_k127_3513658_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 586.0
HKD1_k127_3513658_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 477.0
HKD1_k127_3513658_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 325.0
HKD1_k127_3513658_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 297.0
HKD1_k127_3513658_5 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 302.0
HKD1_k127_3513658_6 - - - - 0.00000000000000000000000000000000000000000000000000000000036 205.0
HKD1_k127_3513658_8 sequence-specific DNA binding K15539 - - 0.000000000000000000000008974 115.0
HKD1_k127_3516116_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 424.0
HKD1_k127_3516116_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000006955 161.0
HKD1_k127_3516116_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000001374 98.0
HKD1_k127_3516116_3 Protein of unknown function (FYDLN_acid) - - - 0.000000000000000000001517 94.0
HKD1_k127_3516116_5 Deoxyribose-phosphate aldolase K01619 - 4.1.2.4 0.0003761 47.0
HKD1_k127_3528490_0 PFAM MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 437.0
HKD1_k127_3528490_1 PFAM MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 349.0
HKD1_k127_3528490_2 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000002247 133.0
HKD1_k127_3540154_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 500.0
HKD1_k127_3540154_1 methyltransferase activity K13613,K15677 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
HKD1_k127_3540154_2 B12 binding domain K01849 - 5.4.99.2 0.0000000000000005968 92.0
HKD1_k127_3568245_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 542.0
HKD1_k127_3568245_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000152 183.0
HKD1_k127_3582609_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 2.523e-197 626.0
HKD1_k127_3582609_1 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000004461 158.0
HKD1_k127_3582609_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000257 89.0
HKD1_k127_3583777_0 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 527.0
HKD1_k127_3583777_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 488.0
HKD1_k127_3583777_2 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 384.0
HKD1_k127_3583777_3 transcriptional regulator K09017,K18301 - - 0.000000000000000000000000000000000000000000000000001463 190.0
HKD1_k127_3584731_0 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 365.0
HKD1_k127_3584731_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000297 197.0
HKD1_k127_3584731_2 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000000000000000001013 176.0
HKD1_k127_3584731_3 PFAM ABC transporter - - - 0.00000000000000000000000000000000000005834 143.0
HKD1_k127_3631031_0 Type III secretion protein K03230 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 353.0
HKD1_k127_3631031_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K03229 - - 0.00000000000000000000000000000000000000000000000000000000009884 216.0
HKD1_k127_3634186_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 2.044e-215 686.0
HKD1_k127_3634186_1 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000009025 234.0
HKD1_k127_3634186_2 XdhC and CoxI family - - - 0.0000000000000000000000000000000002886 143.0
HKD1_k127_3634186_4 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000006354 133.0
HKD1_k127_3635759_0 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 316.0
HKD1_k127_3635759_1 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000004509 158.0
HKD1_k127_3635759_2 UPF0313 protein - - - 0.0000000000000000004721 87.0
HKD1_k127_3635759_3 Glycosyl transferase family 2 - - - 0.000003036 50.0
HKD1_k127_364758_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 502.0
HKD1_k127_364758_1 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 305.0
HKD1_k127_364758_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 299.0
HKD1_k127_3647874_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 617.0
HKD1_k127_3647874_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000006004 96.0
HKD1_k127_3647874_2 penicillin-binding protein K03587 - 3.4.16.4 0.000000000000002892 79.0
HKD1_k127_3689013_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.965e-309 955.0
HKD1_k127_3689013_1 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007967 301.0
HKD1_k127_3721324_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 594.0
HKD1_k127_3721324_1 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001555 290.0
HKD1_k127_3721324_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000001987 81.0
HKD1_k127_3734165_0 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 296.0
HKD1_k127_3734165_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001178 264.0
HKD1_k127_3734165_2 OsmC-like protein K04063 - - 0.0000000000000000000000000000004474 128.0
HKD1_k127_3734165_3 transcriptional regulator - - - 0.0000000000000000000000001246 111.0
HKD1_k127_3741305_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 356.0
HKD1_k127_3741305_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000002613 56.0
HKD1_k127_3745397_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004478 280.0
HKD1_k127_3745397_1 Smr domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
HKD1_k127_3745397_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000004089 187.0
HKD1_k127_3745397_3 - - - - 0.00000000000000000000000000000000573 134.0
HKD1_k127_3754802_0 general secretion pathway protein K02456,K02457,K02459,K10927,K12285 - - 0.00000000000000000000000000000000000000000000000001161 187.0
HKD1_k127_3754802_1 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000005867 161.0
HKD1_k127_3757431_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 490.0
HKD1_k127_3757431_1 DNA polymerase III K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 403.0
HKD1_k127_3765262_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 482.0
HKD1_k127_3765262_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 316.0
HKD1_k127_3780003_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 291.0
HKD1_k127_3780003_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001878 276.0
HKD1_k127_3780003_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008237 258.0
HKD1_k127_3780003_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000815 132.0
HKD1_k127_3781260_0 Domain of unknown function (DUF4175) - - - 2.683e-219 708.0
HKD1_k127_3781260_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 518.0
HKD1_k127_3781260_2 ATPase associated with various cellular activities K03924 - - 0.0003199 53.0
HKD1_k127_3802508_0 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 338.0
HKD1_k127_3802508_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 251.0
HKD1_k127_3802508_2 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000001992 180.0
HKD1_k127_3802508_3 - - - - 0.000000000000000000000000000527 123.0
HKD1_k127_3810507_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 366.0
HKD1_k127_3810507_1 PFAM CBS domain K07182 - - 0.0000000001685 68.0
HKD1_k127_3810507_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000001261 66.0
HKD1_k127_3831000_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 440.0
HKD1_k127_3831000_1 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001772 216.0
HKD1_k127_3831000_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000007678 156.0
HKD1_k127_3831000_3 Cysteine rich repeat K06816 - - 0.0000001051 61.0
HKD1_k127_3871347_0 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000005093 257.0
HKD1_k127_3871347_1 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000004088 196.0
HKD1_k127_3871347_2 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000001157 150.0
HKD1_k127_3871347_3 amine dehydrogenase activity - - - 0.00000000000000000003805 106.0
HKD1_k127_3871347_6 chaperone-mediated protein folding - - - 0.0000006753 60.0
HKD1_k127_3871347_7 Calcium-binding EGF domain - - - 0.000007541 59.0
HKD1_k127_3895300_0 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 351.0
HKD1_k127_3895300_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 312.0
HKD1_k127_3898950_0 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 340.0
HKD1_k127_3898950_1 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000326 246.0
HKD1_k127_3910418_0 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 335.0
HKD1_k127_3910418_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000003526 224.0
HKD1_k127_3910418_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000002844 67.0
HKD1_k127_3929326_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.901e-217 684.0
HKD1_k127_3929326_1 - - - - 0.00000005057 63.0
HKD1_k127_3930211_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 432.0
HKD1_k127_3930211_1 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004044 291.0
HKD1_k127_3930211_2 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000003746 237.0
HKD1_k127_3930211_3 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000001265 156.0
HKD1_k127_3930211_4 ERG2 and Sigma1 receptor like protein K20719 - - 0.00000000000000000000000000000000001557 155.0
HKD1_k127_393285_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 376.0
HKD1_k127_393285_1 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 302.0
HKD1_k127_393285_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003927 216.0
HKD1_k127_393285_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000001618 205.0
HKD1_k127_393285_4 - - - - 0.000000000000000000000000000000000002193 158.0
HKD1_k127_3943507_0 phosphatidylinositol metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 398.0
HKD1_k127_3943507_1 FtsZ-dependent cytokinesis K03975 - - 0.00000000000000000000000000000000000000000000000000000000000008997 216.0
HKD1_k127_3943535_0 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
HKD1_k127_3947367_0 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 391.0
HKD1_k127_3947367_2 Regulatory protein, FmdB family - - - 0.0000000000000000000004112 98.0
HKD1_k127_3947367_3 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000001002 54.0
HKD1_k127_3979170_0 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 326.0
HKD1_k127_3979170_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000006265 239.0
HKD1_k127_3979170_2 membrane - - - 0.000000000000000000000000000000000000000000000000003937 207.0
HKD1_k127_3979170_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000008477 128.0
HKD1_k127_4007816_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.737e-256 809.0
HKD1_k127_4007816_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 416.0
HKD1_k127_4007816_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000002176 207.0
HKD1_k127_4014853_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 421.0
HKD1_k127_4014853_1 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002035 250.0
HKD1_k127_4028067_0 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 569.0
HKD1_k127_4028067_1 Enoyl-CoA hydratase/isomerase K15313 - - 0.000000000000000000000000000000000000000000000003321 193.0
HKD1_k127_4032556_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 5.87e-217 677.0
HKD1_k127_4032556_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 341.0
HKD1_k127_4032556_2 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.000002064 51.0
HKD1_k127_4038177_0 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 352.0
HKD1_k127_4038177_1 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000005641 177.0
HKD1_k127_4038177_2 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000001242 136.0
HKD1_k127_4038773_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 7.886e-201 628.0
HKD1_k127_4038773_1 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 599.0
HKD1_k127_4038818_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 1.022e-216 678.0
HKD1_k127_4038818_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000004041 213.0
HKD1_k127_4038818_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000001078 171.0
HKD1_k127_4046815_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.895e-219 699.0
HKD1_k127_4046815_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 384.0
HKD1_k127_4050798_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 504.0
HKD1_k127_4050798_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000006685 203.0
HKD1_k127_4050927_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 597.0
HKD1_k127_4050927_1 Bacterial extracellular solute-binding proteins, family 3 K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 413.0
HKD1_k127_4058570_0 Heat shock 70 kDa protein K04043 - - 8.323e-239 743.0
HKD1_k127_4058570_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 530.0
HKD1_k127_4058570_2 ABC-type branched-chain amino acid transport K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002554 259.0
HKD1_k127_4061406_0 PFAM fumarate lyase K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 412.0
HKD1_k127_4061406_1 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 295.0
HKD1_k127_4061406_2 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000001128 191.0
HKD1_k127_4061406_3 amine dehydrogenase activity - - - 0.000002705 61.0
HKD1_k127_4062139_0 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 293.0
HKD1_k127_4062139_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002585 250.0
HKD1_k127_4067157_0 Response receiver-modulated diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000001198 233.0
HKD1_k127_4067157_1 Universal stress protein family - - - 0.000228 52.0
HKD1_k127_4069724_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.474e-196 624.0
HKD1_k127_4069724_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 367.0
HKD1_k127_4069724_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 348.0
HKD1_k127_4069724_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 324.0
HKD1_k127_4069724_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000004189 217.0
HKD1_k127_4074975_0 oligopeptide transporter, OPT family - - - 0.0 1044.0
HKD1_k127_4074975_1 Serine Threonine protein kinase K12132 - 2.7.11.1 4.383e-195 647.0
HKD1_k127_4074975_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 419.0
HKD1_k127_4074975_3 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 284.0
HKD1_k127_4074975_4 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006833 277.0
HKD1_k127_4074975_5 shikimate kinase activity K00891,K13829 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000005268 210.0
HKD1_k127_4074975_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000003635 205.0
HKD1_k127_4082071_0 Pfam:CPSase_L_chain - - - 0.0 1044.0
HKD1_k127_4082071_1 Pfam:CPSase_L_chain - - - 0.0000000000000000000003986 97.0
HKD1_k127_4084661_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 346.0
HKD1_k127_4084661_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000284 146.0
HKD1_k127_4086512_0 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000002457 106.0
HKD1_k127_4086512_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000006551 121.0
HKD1_k127_4100079_0 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 1.979e-277 867.0
HKD1_k127_4100079_1 4Fe-4S dicluster domain K17051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 521.0
HKD1_k127_4100079_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001686 256.0
HKD1_k127_4100079_3 Cytochrome c K17052 - - 0.000000000000000000000000000000000000000000000000000000000000000000001368 267.0
HKD1_k127_4106706_0 cluster binding protein K18929 - - 2.637e-209 668.0
HKD1_k127_4106706_1 COG0247 Fe-S K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
HKD1_k127_4106706_2 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006466 242.0
HKD1_k127_4106706_3 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000002975 204.0
HKD1_k127_4106706_4 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000009142 153.0
HKD1_k127_4112643_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002405 277.0
HKD1_k127_4112643_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002993 283.0
HKD1_k127_4112643_2 Receptor family ligand binding region K01999 - - 0.000003426 52.0
HKD1_k127_4120584_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.069e-229 739.0
HKD1_k127_4120584_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 571.0
HKD1_k127_4120584_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 456.0
HKD1_k127_4120584_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000008227 232.0
HKD1_k127_4120584_4 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000001836 218.0
HKD1_k127_4122083_0 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 425.0
HKD1_k127_4122083_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
HKD1_k127_4122083_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000001965 214.0
HKD1_k127_4122083_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000004685 202.0
HKD1_k127_4122083_4 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000005179 177.0
HKD1_k127_4122083_5 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000000005393 176.0
HKD1_k127_4122083_6 PFAM Cys Met metabolism PLP-dependent enzyme K01739,K01760 - 2.5.1.48,4.4.1.8 0.0000000002722 62.0
HKD1_k127_4128942_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 561.0
HKD1_k127_4128942_1 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006642 275.0
HKD1_k127_4132778_0 PFAM Iron-containing alcohol dehydrogenase K19714 - 1.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 472.0
HKD1_k127_4132778_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979,K19714 - 1.1.3.48,2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 312.0
HKD1_k127_4132778_2 Belongs to the DegT DnrJ EryC1 family K19715 - 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 290.0
HKD1_k127_4132778_3 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
HKD1_k127_4139951_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 407.0
HKD1_k127_4139951_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001745 281.0
HKD1_k127_4139951_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001246 286.0
HKD1_k127_4139951_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000009665 207.0
HKD1_k127_4139951_4 guanyl-nucleotide exchange factor activity K01179 - 3.2.1.4 0.0001677 48.0
HKD1_k127_4148392_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 571.0
HKD1_k127_4148392_1 Domain of unknown function (DUF4912) K09942 - - 0.0000000000003208 81.0
HKD1_k127_4158277_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 540.0
HKD1_k127_4158277_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 526.0
HKD1_k127_4167186_0 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 461.0
HKD1_k127_4167186_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 392.0
HKD1_k127_4167186_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000007332 113.0
HKD1_k127_4201677_0 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 541.0
HKD1_k127_4201677_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000002739 59.0
HKD1_k127_421221_0 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 577.0
HKD1_k127_421221_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 325.0
HKD1_k127_421221_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000001947 207.0
HKD1_k127_4221745_0 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 325.0
HKD1_k127_4221745_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005448 277.0
HKD1_k127_4221745_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000000000000004146 90.0
HKD1_k127_4221745_4 diguanylate cyclase - - - 0.00000000001487 75.0
HKD1_k127_4224859_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 404.0
HKD1_k127_4224859_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000007677 216.0
HKD1_k127_4224859_2 Tetratricopeptide repeat - - - 0.0005356 50.0
HKD1_k127_4248146_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 431.0
HKD1_k127_4248146_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 422.0
HKD1_k127_4248146_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 291.0
HKD1_k127_4248146_3 TPR repeat - - - 0.0001486 52.0
HKD1_k127_4248305_0 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 456.0
HKD1_k127_4248305_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 414.0
HKD1_k127_4248305_2 Polysaccharide deacetylase K11931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 342.0
HKD1_k127_4248305_3 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564 - 0.0000000000000000000004925 102.0
HKD1_k127_4248305_4 - - - - 0.0001622 48.0
HKD1_k127_4257005_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
HKD1_k127_4257005_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 362.0
HKD1_k127_4257005_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005814 307.0
HKD1_k127_4257005_3 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000003383 140.0
HKD1_k127_4257005_4 Receptor family ligand binding region K01999 - - 0.000000004847 57.0
HKD1_k127_4258993_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 410.0
HKD1_k127_4258993_1 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006159 280.0
HKD1_k127_42649_0 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000004324 179.0
HKD1_k127_42649_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000002268 123.0
HKD1_k127_42649_3 Transcriptional regulator, LysR family - - - 0.000000000248 61.0
HKD1_k127_4265899_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 345.0
HKD1_k127_4265899_1 PFAM ThiJ PfpI domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 299.0
HKD1_k127_4266381_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002661 246.0
HKD1_k127_4266381_1 Protein of unknown function (DUF2953) - - - 0.00000000000000000000000005438 111.0
HKD1_k127_4266381_2 - - - - 0.000000000000000000000000129 112.0
HKD1_k127_4266381_4 - - - - 0.0001146 49.0
HKD1_k127_4268872_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 488.0
HKD1_k127_4268872_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000003337 89.0
HKD1_k127_4274781_0 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 575.0
HKD1_k127_4274781_1 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 375.0
HKD1_k127_4274781_2 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000002115 163.0
HKD1_k127_4274781_3 Belongs to the UPF0250 family K09158 - - 0.00000000000002883 85.0
HKD1_k127_4282821_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 522.0
HKD1_k127_4282821_1 dEAD DEAH box helicase K03724,K06877 - - 0.00000000000000000000000000000000000000005125 154.0
HKD1_k127_4300590_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 9.208e-234 737.0
HKD1_k127_4300590_1 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000003936 248.0
HKD1_k127_4304988_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
HKD1_k127_4304988_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000002062 265.0
HKD1_k127_4304988_3 KR domain K16216 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0031224,GO:0044424,GO:0044425,GO:0044464,GO:0050664,GO:0055114 1.1.1.320 0.000001973 53.0
HKD1_k127_4311046_0 AAA C-terminal domain K07478 - - 2.416e-208 670.0
HKD1_k127_4311046_1 Response regulator receiver - - - 1.135e-203 640.0
HKD1_k127_4311046_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 410.0
HKD1_k127_4311046_3 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001736 262.0
HKD1_k127_4311046_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000001409 137.0
HKD1_k127_4311046_5 - - - - 0.000003047 55.0
HKD1_k127_4312354_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 374.0
HKD1_k127_4312354_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 344.0
HKD1_k127_4312354_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 276.0
HKD1_k127_4312354_3 energy transducer activity K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001612 246.0
HKD1_k127_4312354_4 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000001799 220.0
HKD1_k127_4312354_5 biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000002623 205.0
HKD1_k127_4312354_6 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000001881 194.0
HKD1_k127_4312354_7 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000003552 151.0
HKD1_k127_4354272_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 469.0
HKD1_k127_4354272_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 451.0
HKD1_k127_4354272_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 415.0
HKD1_k127_4354272_3 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.0000000000000000000000000000000000000000000000000000000000000002407 240.0
HKD1_k127_4365166_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 3.834e-289 896.0
HKD1_k127_4365166_1 GMC oxidoreductase K03333 - 1.1.3.6 1.851e-251 786.0
HKD1_k127_4365166_2 PilZ domain - - - 0.000000008558 64.0
HKD1_k127_4371847_0 Major Facilitator Superfamily K02575 GO:0003674,GO:0005215,GO:0005452,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 553.0
HKD1_k127_4371847_1 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 450.0
HKD1_k127_4389724_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 474.0
HKD1_k127_4389724_1 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 394.0
HKD1_k127_4389724_2 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000006412 199.0
HKD1_k127_4389724_3 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.00000000000000000000000002138 115.0
HKD1_k127_4391599_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 521.0
HKD1_k127_4391599_1 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 430.0
HKD1_k127_4391599_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 337.0
HKD1_k127_4409588_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 447.0
HKD1_k127_4409588_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 283.0
HKD1_k127_4409588_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 287.0
HKD1_k127_4409588_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004679 248.0
HKD1_k127_4409588_4 Rod shape-determining protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000005929 229.0
HKD1_k127_4409588_5 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.00000000000000000000000000000000000000000000000000000206 194.0
HKD1_k127_4409588_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000008548 177.0
HKD1_k127_442899_0 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 434.0
HKD1_k127_442899_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 422.0
HKD1_k127_442899_2 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000003199 252.0
HKD1_k127_442899_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000002227 83.0
HKD1_k127_442899_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000002361 86.0
HKD1_k127_4430187_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.602e-269 851.0
HKD1_k127_4438000_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1009.0
HKD1_k127_4438000_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.619e-222 700.0
HKD1_k127_4438000_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 605.0
HKD1_k127_4438000_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 368.0
HKD1_k127_4438000_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 330.0
HKD1_k127_4438000_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006825 247.0
HKD1_k127_4438000_6 protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000000000000000000000000000000000000456 226.0
HKD1_k127_4438000_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000001507 157.0
HKD1_k127_4438000_8 Glutamine amidotransferases class-II - - - 0.000000000000000000001443 96.0
HKD1_k127_4464079_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 452.0
HKD1_k127_4464079_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
HKD1_k127_4477078_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 399.0
HKD1_k127_4477078_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004794 262.0
HKD1_k127_4477078_2 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000001273 156.0
HKD1_k127_4477078_3 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000007957 144.0
HKD1_k127_4501565_0 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 420.0
HKD1_k127_4501565_1 Surface antigen - - - 0.0000671 52.0
HKD1_k127_4503273_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 2.088e-224 705.0
HKD1_k127_4504923_0 twitching motility protein K02669 - - 2.77e-208 651.0
HKD1_k127_4504923_1 PilZ domain - - - 0.000000000000000000000000000000000000002427 163.0
HKD1_k127_4506347_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 1.653e-303 945.0
HKD1_k127_4506347_1 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000000000000000000002589 182.0
HKD1_k127_4506347_2 Cytochrome c - - - 0.000000000000000000000000000009311 125.0
HKD1_k127_4506347_3 2 iron, 2 sulfur cluster binding K13643 - - 0.0000000000000000001586 98.0
HKD1_k127_4516131_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 9.281e-231 727.0
HKD1_k127_4540760_0 cluster binding protein - - - 7.199e-309 959.0
HKD1_k127_4540760_1 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 425.0
HKD1_k127_4540760_2 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002781 242.0
HKD1_k127_4542907_0 PFAM Sulfatase K01130 - 3.1.6.1 5.001e-243 762.0
HKD1_k127_4542907_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000002426 94.0
HKD1_k127_4577657_0 iron-sulfur binding K00184 - - 3.821e-241 764.0
HKD1_k127_4580334_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.369e-292 908.0
HKD1_k127_4580334_1 General secretory system II, protein E domain protein K02454 - - 6.182e-221 691.0
HKD1_k127_4580334_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 430.0
HKD1_k127_4580334_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 306.0
HKD1_k127_4580334_4 Regulatory protein, FmdB family - - - 0.000000000000000002865 89.0
HKD1_k127_4583599_0 Elongator protein 3, MiaB family, Radical SAM - - - 7.263e-278 868.0
HKD1_k127_4583599_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 475.0
HKD1_k127_4583599_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000001148 224.0
HKD1_k127_4583599_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000001237 98.0
HKD1_k127_4585834_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 486.0
HKD1_k127_4585834_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007521 270.0
HKD1_k127_4585834_2 - - - - 0.0000000000000000000001597 102.0
HKD1_k127_4585834_3 Protein of unknown function (DUF4231) - - - 0.000000000000000001167 99.0
HKD1_k127_4586581_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 602.0
HKD1_k127_4586581_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001219 242.0
HKD1_k127_4586581_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000834 130.0
HKD1_k127_4587086_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 1.651e-215 685.0
HKD1_k127_4587086_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 544.0
HKD1_k127_4596210_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 6.633e-313 967.0
HKD1_k127_4596210_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004486 279.0
HKD1_k127_4596210_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000002006 87.0
HKD1_k127_4604021_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 511.0
HKD1_k127_4604021_1 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 316.0
HKD1_k127_4604021_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 295.0
HKD1_k127_4607013_0 Peptidase S46 - - - 1.09e-248 784.0
HKD1_k127_4611019_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 588.0
HKD1_k127_4611019_1 - - - - 0.0000000000000000000000000003564 119.0
HKD1_k127_4615319_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.000000000000000000000000000000000002942 157.0
HKD1_k127_4615319_1 Histidine kinase - - - 0.0000000000000000000000009413 111.0
HKD1_k127_4615319_2 sensory box sensor histidine kinase VC1084 imported - - - 0.000000000000001609 85.0
HKD1_k127_4621126_0 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000000000000000000000000000000000001181 174.0
HKD1_k127_4621126_1 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000001896 93.0
HKD1_k127_4623345_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 510.0
HKD1_k127_4623345_1 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 476.0
HKD1_k127_4623345_2 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001201 286.0
HKD1_k127_4623345_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007689 267.0
HKD1_k127_4623345_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
HKD1_k127_4623345_5 thioesterase K07107 - - 0.00000000000000000000000000000000000000000000006793 171.0
HKD1_k127_4641527_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003261 276.0
HKD1_k127_4641527_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000001895 155.0
HKD1_k127_4641527_2 ABC transporter K01995 - - 0.0000000000000000000000000132 112.0
HKD1_k127_4654976_0 Aminotransferase K01845 - 5.4.3.8 1.651e-205 662.0
HKD1_k127_4654976_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 364.0
HKD1_k127_4654976_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 309.0
HKD1_k127_4654976_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000001739 159.0
HKD1_k127_4655426_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.223e-236 744.0
HKD1_k127_4655426_1 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 300.0
HKD1_k127_4659333_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1288.0
HKD1_k127_4659333_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 527.0
HKD1_k127_4659333_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000001128 236.0
HKD1_k127_4660292_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 368.0
HKD1_k127_4660292_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 371.0
HKD1_k127_4660292_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000001005 72.0
HKD1_k127_4666451_0 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000174 277.0
HKD1_k127_4666451_1 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002165 264.0
HKD1_k127_4673532_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 459.0
HKD1_k127_4673532_1 organic acid phosphorylation K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 358.0
HKD1_k127_4673532_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 370.0
HKD1_k127_4673532_3 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002159 258.0
HKD1_k127_4673532_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000005254 240.0
HKD1_k127_4673532_5 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000000000000001849 109.0
HKD1_k127_4679520_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.58e-246 775.0
HKD1_k127_4682208_0 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 289.0
HKD1_k127_4682208_1 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000001238 117.0
HKD1_k127_4682208_3 Calcineurin-like phosphoesterase - - - 0.000000000000003255 77.0
HKD1_k127_47008_0 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 408.0
HKD1_k127_47008_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
HKD1_k127_47008_2 Methyltransferase domain - - - 0.00000000000000005406 82.0
HKD1_k127_4708976_0 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 599.0
HKD1_k127_4708976_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 559.0
HKD1_k127_4708976_2 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001553 280.0
HKD1_k127_4709867_0 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000004231 250.0
HKD1_k127_4709867_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000338 224.0
HKD1_k127_4709867_2 pseudouridine synthase activity K06176 - 5.4.99.27 0.00000000000000000000002723 102.0
HKD1_k127_474346_0 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 462.0
HKD1_k127_474346_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001371 283.0
HKD1_k127_474346_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000003738 262.0
HKD1_k127_4749570_0 response regulator K07713 - - 2.991e-197 656.0
HKD1_k127_4749570_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 553.0
HKD1_k127_4749570_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 411.0
HKD1_k127_4749570_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
HKD1_k127_4753695_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 7.149e-194 614.0
HKD1_k127_4753695_1 PFAM Ammonium Transporter Family K03320 - - 0.00000000000000000000000000697 113.0
HKD1_k127_4756583_0 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 614.0
HKD1_k127_4756583_1 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000003676 193.0
HKD1_k127_477584_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 2.862e-251 792.0
HKD1_k127_477584_1 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000004616 216.0
HKD1_k127_477584_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000003686 211.0
HKD1_k127_4810256_0 Strictosidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 299.0
HKD1_k127_4810256_1 Histidine kinase - - - 0.00000000000000000000000004096 117.0
HKD1_k127_4810256_2 Predicted Zn-dependent protease (DUF2268) - - - 0.000000000000000000004979 95.0
HKD1_k127_4822928_0 - - - - 0.0000000006633 72.0
HKD1_k127_4836753_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 5.135e-217 699.0
HKD1_k127_4837938_0 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 404.0
HKD1_k127_4837938_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 345.0
HKD1_k127_4837938_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 329.0
HKD1_k127_4837938_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002522 286.0
HKD1_k127_4837938_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
HKD1_k127_4837938_6 Protein of unknown function (DUF3108) - - - 0.00000000000004952 75.0
HKD1_k127_4914833_0 domain, Protein - - - 1.494e-266 835.0
HKD1_k127_4926494_0 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 397.0
HKD1_k127_4926494_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000001789 224.0
HKD1_k127_4926494_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000006849 216.0
HKD1_k127_493270_0 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 482.0
HKD1_k127_493270_1 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000002571 147.0
HKD1_k127_49450_0 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.138e-200 628.0
HKD1_k127_49450_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 365.0
HKD1_k127_49450_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000007131 220.0
HKD1_k127_49450_3 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000009904 158.0
HKD1_k127_49450_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000001566 106.0
HKD1_k127_49450_5 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00001591 47.0
HKD1_k127_4947337_0 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 514.0
HKD1_k127_4947337_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 281.0
HKD1_k127_4947337_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000006053 55.0
HKD1_k127_495737_0 Histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 534.0
HKD1_k127_495737_1 ATPase activity K16784,K16786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 369.0
HKD1_k127_495737_2 TonB-dependent copper receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001355 252.0
HKD1_k127_495737_3 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000000000000000000007367 232.0
HKD1_k127_495737_4 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000002654 152.0
HKD1_k127_495737_5 - K16783 - - 0.0000000000000000000000000136 125.0
HKD1_k127_4985069_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 466.0
HKD1_k127_4985069_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 389.0
HKD1_k127_4987718_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 431.0
HKD1_k127_4987718_1 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 265.0
HKD1_k127_4987718_2 fibroblast growth factor binding K06816 GO:0000137,GO:0000138,GO:0000139,GO:0001501,GO:0002376,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005797,GO:0005886,GO:0006810,GO:0006886,GO:0006928,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009887,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010955,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016477,GO:0017015,GO:0017134,GO:0019222,GO:0019838,GO:0023051,GO:0023057,GO:0030162,GO:0030512,GO:0031012,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031984,GO:0031985,GO:0032268,GO:0032269,GO:0032330,GO:0032501,GO:0032502,GO:0033036,GO:0034613,GO:0040011,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045861,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050900,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051641,GO:0051649,GO:0051674,GO:0060255,GO:0060348,GO:0060349,GO:0061035,GO:0065007,GO:0070613,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0080090,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0098588,GO:0098791,GO:1903317,GO:1903318,GO:1903844,GO:1903845,GO:2000026 - 0.000000000000002366 86.0
HKD1_k127_4995820_0 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 293.0
HKD1_k127_4995820_1 PFAM Fimbrial assembly family protein K02663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005062 248.0
HKD1_k127_4995820_2 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000296 125.0
HKD1_k127_4999247_0 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 318.0
HKD1_k127_4999247_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000002796 165.0
HKD1_k127_4999247_2 amine dehydrogenase activity - - - 0.00000000000000000000000000001304 129.0
HKD1_k127_5004896_0 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 336.0
HKD1_k127_5004896_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000153 197.0
HKD1_k127_5004896_2 Sodium:solute symporter family K14393 - - 0.00000000000000000000000000000000000000001049 159.0
HKD1_k127_5004896_3 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000741 157.0
HKD1_k127_5006986_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 434.0
HKD1_k127_5006986_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 341.0
HKD1_k127_501946_0 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 491.0
HKD1_k127_501946_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000005871 212.0
HKD1_k127_501946_2 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000001876 193.0
HKD1_k127_501946_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000001471 178.0
HKD1_k127_501946_4 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000000000000001381 88.0
HKD1_k127_5026800_0 Beta-Casp domain K07576 - - 2.392e-200 633.0
HKD1_k127_5026800_1 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 377.0
HKD1_k127_5026800_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000001192 241.0
HKD1_k127_5026800_3 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000001776 125.0
HKD1_k127_5026800_4 Nudix hydrolase K03574 - 3.6.1.55 0.00000000000000000000448 108.0
HKD1_k127_5027541_0 PFAM Alcohol dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 521.0
HKD1_k127_5027541_1 PFAM nickel-dependent hydrogenase large subunit K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 457.0
HKD1_k127_5027541_2 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 399.0
HKD1_k127_5027541_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K05588 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000201 233.0
HKD1_k127_5027541_4 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000005335 183.0
HKD1_k127_5029777_0 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 583.0
HKD1_k127_5029777_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000003367 119.0
HKD1_k127_5029777_2 Protein of unknown function (DUF2867) - - - 0.00000000000000000111 87.0
HKD1_k127_5030914_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000003737 180.0
HKD1_k127_5030914_1 - - - - 0.00000000000000000000000000000000187 147.0
HKD1_k127_5034103_0 protein related to plant photosystem II stability assembly factor - - - 1.028e-202 636.0
HKD1_k127_5034103_1 ThiS family K03636 - - 0.00000000000000000000000006503 123.0
HKD1_k127_5034103_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000003691 51.0
HKD1_k127_5046677_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1101.0
HKD1_k127_5046677_1 ABC transporter K06147,K06148 - - 8.302e-288 894.0
HKD1_k127_5046677_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 424.0
HKD1_k127_5046677_3 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006637 294.0
HKD1_k127_5046677_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001498 254.0
HKD1_k127_5046677_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
HKD1_k127_5046677_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000002299 194.0
HKD1_k127_5046677_7 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000006383 203.0
HKD1_k127_5052123_0 DEAD/H associated K03724 - - 0.0 1030.0
HKD1_k127_5053319_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.059e-218 681.0
HKD1_k127_5053319_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 355.0
HKD1_k127_5053319_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001868 278.0
HKD1_k127_5064527_0 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 362.0
HKD1_k127_5064527_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 354.0
HKD1_k127_5075455_0 PFAM amidohydrolase K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 437.0
HKD1_k127_5075455_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 405.0
HKD1_k127_5075455_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000009625 64.0
HKD1_k127_5075455_3 - - - - 0.00000002287 67.0
HKD1_k127_50781_0 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 507.0
HKD1_k127_50781_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 434.0
HKD1_k127_50781_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 369.0
HKD1_k127_50781_3 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005626 264.0
HKD1_k127_50781_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000001427 229.0
HKD1_k127_50781_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000001797 155.0
HKD1_k127_50781_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000004356 102.0
HKD1_k127_5083120_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 9.761e-253 800.0
HKD1_k127_5083120_1 Sir2 family - - - 0.000000000000000000002483 94.0
HKD1_k127_5083120_2 - - - - 0.00004334 55.0
HKD1_k127_5093655_0 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 490.0
HKD1_k127_5093655_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 382.0
HKD1_k127_5093655_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003648 282.0
HKD1_k127_5093655_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000002152 174.0
HKD1_k127_5093655_4 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000000000004877 160.0
HKD1_k127_5093655_5 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000001785 121.0
HKD1_k127_5093655_7 PFAM secretion protein HlyD family protein - - - 0.000000000000000000002087 110.0
HKD1_k127_5093655_8 Iron-sulphur cluster biosynthesis K22072 GO:0003674,GO:0005488,GO:0005506,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - 0.0003507 45.0
HKD1_k127_5100793_0 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 597.0
HKD1_k127_510671_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001215 249.0
HKD1_k127_510671_1 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000001084 132.0
HKD1_k127_5107776_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 422.0
HKD1_k127_5107776_1 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 335.0
HKD1_k127_5107776_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000007716 189.0
HKD1_k127_5107776_3 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001191 147.0
HKD1_k127_5107776_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000002464 123.0
HKD1_k127_5124089_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 396.0
HKD1_k127_5124089_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003958 267.0
HKD1_k127_5124089_2 AMP binding - GO:0008150,GO:0040007 - 0.000000000000000007393 97.0
HKD1_k127_5124601_0 Rod shape-determining protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 475.0
HKD1_k127_5124601_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003112 302.0
HKD1_k127_5124601_2 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000000009279 166.0
HKD1_k127_5129785_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.95e-241 748.0
HKD1_k127_5129785_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 8.431e-221 704.0
HKD1_k127_5129785_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000002348 223.0
HKD1_k127_5129785_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000003745 81.0
HKD1_k127_5148455_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.709e-276 856.0
HKD1_k127_5148455_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 608.0
HKD1_k127_5148455_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 490.0
HKD1_k127_5148455_3 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 355.0
HKD1_k127_5148455_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 331.0
HKD1_k127_5148455_5 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 312.0
HKD1_k127_5148455_6 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007792 260.0
HKD1_k127_5148455_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000001252 252.0
HKD1_k127_5148455_8 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000001025 214.0
HKD1_k127_5148455_9 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000004903 215.0
HKD1_k127_5179215_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 490.0
HKD1_k127_5179215_1 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003427 245.0
HKD1_k127_5179215_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000467 164.0
HKD1_k127_5179215_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000003649 89.0
HKD1_k127_5190214_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.481e-200 638.0
HKD1_k127_5190214_1 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 625.0
HKD1_k127_5190214_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 262.0
HKD1_k127_5193988_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 466.0
HKD1_k127_5208336_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 358.0
HKD1_k127_5208336_1 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000006894 206.0
HKD1_k127_5217032_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 593.0
HKD1_k127_5217032_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 552.0
HKD1_k127_522210_0 Pfam Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 299.0
HKD1_k127_5224645_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 304.0
HKD1_k127_5224645_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001793 140.0
HKD1_k127_5224645_2 zinc ion binding K06204 - - 0.00000000000000000000001055 104.0
HKD1_k127_5224645_3 response regulator K02481,K07713 - - 0.00000007661 55.0
HKD1_k127_5227764_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 497.0
HKD1_k127_5227764_1 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 354.0
HKD1_k127_5237477_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 340.0
HKD1_k127_5237477_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000005152 167.0
HKD1_k127_5237477_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001395 174.0
HKD1_k127_5248425_0 FAD linked oxidase domain protein - - - 2.313e-294 917.0
HKD1_k127_5248425_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001583 239.0
HKD1_k127_5248425_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000001965 196.0
HKD1_k127_5248425_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000004666 116.0
HKD1_k127_5259090_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 2.288e-196 618.0
HKD1_k127_5259116_0 Belongs to the BI1 family K06890,K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005804 286.0
HKD1_k127_5259116_1 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000846 140.0
HKD1_k127_526644_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 458.0
HKD1_k127_526644_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000006178 207.0
HKD1_k127_5273143_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.004e-267 834.0
HKD1_k127_5279036_0 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 379.0
HKD1_k127_5279727_0 MMPL family K03296,K18138 - - 2.9e-217 680.0
HKD1_k127_5279727_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 459.0
HKD1_k127_5279727_2 NmrA-like family - - - 0.000000000000000000000000000001864 125.0
HKD1_k127_5279727_3 - - - - 0.00000000000000000001236 103.0
HKD1_k127_5293021_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.641e-218 681.0
HKD1_k127_5293021_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000008041 238.0
HKD1_k127_5299707_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 6.525e-238 739.0
HKD1_k127_5299707_1 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 304.0
HKD1_k127_5326248_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 9.213e-214 679.0
HKD1_k127_5326248_1 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 442.0
HKD1_k127_5326248_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000005849 207.0
HKD1_k127_5326248_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000004927 168.0
HKD1_k127_5329879_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000002532 192.0
HKD1_k127_5330586_0 NADPH quinone K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 363.0
HKD1_k127_5330586_1 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000007282 128.0
HKD1_k127_5330586_2 Thioesterase superfamily protein - - - 0.0000000000000000000000001894 121.0
HKD1_k127_5330586_3 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000005342 90.0
HKD1_k127_5340660_0 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004687 266.0
HKD1_k127_5340660_1 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000001684 103.0
HKD1_k127_5353933_0 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000361 273.0
HKD1_k127_5359687_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1126.0
HKD1_k127_5359687_1 Exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 295.0
HKD1_k127_5359687_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000943 283.0
HKD1_k127_5359687_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000003526 255.0
HKD1_k127_5375806_0 TrkA-C domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 501.0
HKD1_k127_5375806_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 342.0
HKD1_k127_5375806_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001766 259.0
HKD1_k127_5375806_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000005101 241.0
HKD1_k127_5375806_4 SnoaL-like domain - - - 0.00000000000000000000000004835 127.0
HKD1_k127_5385305_0 COGs COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 604.0
HKD1_k127_5385305_1 HI0933-like protein - - - 0.00000000000000000000000000000001129 132.0
HKD1_k127_5385305_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0001411 45.0
HKD1_k127_539042_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 413.0
HKD1_k127_539042_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 421.0
HKD1_k127_539042_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 294.0
HKD1_k127_539042_3 PFAM ABC transporter K01990,K01992,K09695 - - 0.000000000000000000000000000000000000001646 149.0
HKD1_k127_5394188_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 7.565e-200 630.0
HKD1_k127_5405452_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 9.184e-245 764.0
HKD1_k127_5414638_0 SMART Elongator protein 3 MiaB NifB - - - 5.307e-215 675.0
HKD1_k127_5414638_1 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000003934 99.0
HKD1_k127_5417044_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.073e-219 692.0
HKD1_k127_5417044_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 484.0
HKD1_k127_5417044_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 462.0
HKD1_k127_5417044_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 359.0
HKD1_k127_5417044_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 350.0
HKD1_k127_5417044_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 370.0
HKD1_k127_5417044_6 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000001502 224.0
HKD1_k127_5417044_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000003819 136.0
HKD1_k127_5431786_0 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 382.0
HKD1_k127_5431786_1 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000005318 245.0
HKD1_k127_5446708_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 488.0
HKD1_k127_5446708_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 437.0
HKD1_k127_5457157_0 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008617 272.0
HKD1_k127_5457157_1 Multicopper oxidase - - - 0.000000000000000006494 95.0
HKD1_k127_5457157_2 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.0000000374 66.0
HKD1_k127_5457157_3 UbiA prenyltransferase family - - - 0.000003583 49.0
HKD1_k127_5460530_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.355e-268 858.0
HKD1_k127_5460530_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 473.0
HKD1_k127_5460530_2 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 371.0
HKD1_k127_5460530_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003483 273.0
HKD1_k127_5460530_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000003605 98.0
HKD1_k127_548137_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 462.0
HKD1_k127_548137_1 mRNA catabolic process - - - 0.00000000000004153 85.0
HKD1_k127_5489317_0 Chromosome Partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
HKD1_k127_5489317_1 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005809 249.0
HKD1_k127_5489317_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.00002315 47.0
HKD1_k127_5502348_0 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002283 187.0
HKD1_k127_5502348_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000398 133.0
HKD1_k127_5502348_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.00000000000000000000000003163 108.0
HKD1_k127_550632_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000009155 252.0
HKD1_k127_550632_2 amine dehydrogenase activity - - - 0.0000000000000000002902 88.0
HKD1_k127_5510402_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 357.0
HKD1_k127_5510402_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001324 257.0
HKD1_k127_5510402_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000002762 61.0
HKD1_k127_5510852_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 480.0
HKD1_k127_5510852_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 377.0
HKD1_k127_5510852_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 346.0
HKD1_k127_5510852_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000005513 153.0
HKD1_k127_5510852_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000001698 91.0
HKD1_k127_554131_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 383.0
HKD1_k127_554131_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 350.0
HKD1_k127_554131_2 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000001292 216.0
HKD1_k127_554377_0 Outer membrane efflux protein K15725 - - 0.000000000000000000002238 108.0
HKD1_k127_554377_1 Methionine synthase K00548 - 2.1.1.13 0.00003872 46.0
HKD1_k127_5557558_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 457.0
HKD1_k127_5557558_1 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 357.0
HKD1_k127_5557558_2 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000002154 224.0
HKD1_k127_5567060_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 562.0
HKD1_k127_5567060_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000002324 165.0
HKD1_k127_5567798_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 2.71e-216 688.0
HKD1_k127_5567798_2 HemY protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001216 236.0
HKD1_k127_5568459_0 PFAM Glycoside hydrolase 15-related K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 536.0
HKD1_k127_5568459_1 PFAM Glycosyl transferase, family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000003041 100.0
HKD1_k127_557188_0 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 491.0
HKD1_k127_557188_1 Outer membrane efflux protein - - - 0.000000000000007658 89.0
HKD1_k127_5591469_0 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 455.0
HKD1_k127_5591469_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 455.0
HKD1_k127_5591469_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 416.0
HKD1_k127_5591469_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000004776 217.0
HKD1_k127_5591469_4 - - - - 0.0000000006217 67.0
HKD1_k127_5605854_0 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 537.0
HKD1_k127_5605854_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 466.0
HKD1_k127_5605854_2 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 300.0
HKD1_k127_5605854_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000003554 126.0
HKD1_k127_5610133_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.942e-233 728.0
HKD1_k127_5610133_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
HKD1_k127_5610133_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000002908 179.0
HKD1_k127_5610133_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000004688 157.0
HKD1_k127_5610133_4 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000000000103 148.0
HKD1_k127_5610133_5 Protein of unknown function (DUF503) K09764 - - 0.000000000002993 67.0
HKD1_k127_5624315_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 396.0
HKD1_k127_5647368_0 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000004777 207.0
HKD1_k127_5647368_1 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.0000000000000000000000000000000000000000000000000001225 211.0
HKD1_k127_5647368_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000002187 192.0
HKD1_k127_5690688_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 477.0
HKD1_k127_5690688_1 aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 442.0
HKD1_k127_5690688_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 365.0
HKD1_k127_569150_0 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 485.0
HKD1_k127_569150_1 Dehydrogenase reductase SDR family member K11169 - - 0.0000000000000000000000000000000501 139.0
HKD1_k127_5693028_0 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 505.0
HKD1_k127_5693028_1 Aminotransferase, class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 488.0
HKD1_k127_5693028_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000001035 129.0
HKD1_k127_5697647_0 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 427.0
HKD1_k127_5697647_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 423.0
HKD1_k127_5697647_2 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000007669 153.0
HKD1_k127_5702474_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 493.0
HKD1_k127_5702474_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 255.0
HKD1_k127_5712178_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 535.0
HKD1_k127_5712178_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 473.0
HKD1_k127_5712178_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 299.0
HKD1_k127_5720138_0 Pfam Transposase IS66 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 402.0
HKD1_k127_5720138_1 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000002123 217.0
HKD1_k127_5720138_2 - - - - 0.0000000000000000000000000000000000000006263 154.0
HKD1_k127_5734941_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1377.0
HKD1_k127_5734941_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 332.0
HKD1_k127_5734941_2 spore germination K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000001143 245.0
HKD1_k127_5747581_0 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000004659 217.0
HKD1_k127_5747581_1 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
HKD1_k127_5747581_2 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000003043 192.0
HKD1_k127_5767096_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 562.0
HKD1_k127_5767096_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 398.0
HKD1_k127_5767096_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 319.0
HKD1_k127_5767096_3 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005083 263.0
HKD1_k127_5767096_4 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000005124 207.0
HKD1_k127_5767096_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000006772 74.0
HKD1_k127_5774728_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
HKD1_k127_5774728_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000008747 85.0
HKD1_k127_5774728_2 PilZ domain - - - 0.00004963 54.0
HKD1_k127_5794283_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 460.0
HKD1_k127_5794283_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 339.0
HKD1_k127_5794283_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000003236 203.0
HKD1_k127_5820081_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.856e-230 738.0
HKD1_k127_5820081_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 365.0
HKD1_k127_5820081_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000003196 225.0
HKD1_k127_5820081_3 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000002488 212.0
HKD1_k127_5820081_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000005747 106.0
HKD1_k127_5858582_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 597.0
HKD1_k127_5858582_1 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 325.0
HKD1_k127_5858582_2 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000004363 247.0
HKD1_k127_5858582_3 Methyltransferase - - - 0.000000000000000000000000002972 118.0
HKD1_k127_5858582_4 Protein of unknown function (DUF1847) - - - 0.000000000000008361 74.0
HKD1_k127_5899568_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 8.964e-298 918.0
HKD1_k127_5899568_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 361.0
HKD1_k127_5910249_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 2.294e-217 685.0
HKD1_k127_5910249_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008187 267.0
HKD1_k127_5910249_2 Ubiquinol-cytochrome C reductase - - - 0.00000000000000000000000000000000009446 145.0
HKD1_k127_5910249_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.00000000000000000000000001339 119.0
HKD1_k127_5921540_0 Belongs to the CinA family K03742,K03743 - 3.5.1.42 2.114e-199 629.0
HKD1_k127_5936444_0 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 316.0
HKD1_k127_5936444_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004549 279.0
HKD1_k127_5936444_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000005567 229.0
HKD1_k127_5936444_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000004267 233.0
HKD1_k127_5936444_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000251 105.0
HKD1_k127_5959654_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.939e-245 769.0
HKD1_k127_5959654_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000335 182.0
HKD1_k127_5963238_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.447e-257 809.0
HKD1_k127_5967194_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.0 1080.0
HKD1_k127_5967194_1 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000001219 186.0
HKD1_k127_5967194_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000006443 164.0
HKD1_k127_5967194_3 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000004401 168.0
HKD1_k127_5969257_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 434.0
HKD1_k127_5969257_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 315.0
HKD1_k127_5969257_2 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000000000000000000000000000001025 222.0
HKD1_k127_5978854_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 402.0
HKD1_k127_5978854_1 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003146 287.0
HKD1_k127_5978854_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000005896 98.0
HKD1_k127_5979160_0 heat shock protein 70 K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 616.0
HKD1_k127_5979160_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 473.0
HKD1_k127_5979160_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 379.0
HKD1_k127_5979160_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 351.0
HKD1_k127_5979160_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 300.0
HKD1_k127_598332_0 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001691 247.0
HKD1_k127_598332_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000003402 251.0
HKD1_k127_598332_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000003665 137.0
HKD1_k127_598332_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000006613 84.0
HKD1_k127_5999246_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 354.0
HKD1_k127_5999246_1 Endothelin-converting enzyme K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000001094 150.0
HKD1_k127_6001395_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 362.0
HKD1_k127_6001395_3 Tetratricopeptide repeat - - - 0.000000000811 65.0
HKD1_k127_6001839_0 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 312.0
HKD1_k127_6001839_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000002723 246.0
HKD1_k127_6001839_2 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000001575 248.0
HKD1_k127_6001839_3 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000000000000006331 136.0
HKD1_k127_6032484_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 350.0
HKD1_k127_6032484_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000008338 202.0
HKD1_k127_6036458_0 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 386.0
HKD1_k127_6036458_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003622 293.0
HKD1_k127_6036458_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000000000000000000000000000000000000000000002712 179.0
HKD1_k127_6036458_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000418 90.0
HKD1_k127_6038292_0 Histidine ammonia-lyase K01745 - 4.3.1.3 7.59e-240 758.0
HKD1_k127_6038292_1 aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 367.0
HKD1_k127_6038292_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 301.0
HKD1_k127_6038292_3 cysteine-type peptidase activity K13695 - - 0.0000000000000000000000000000000000000000005436 164.0
HKD1_k127_6038292_4 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000005136 121.0
HKD1_k127_6038853_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 349.0
HKD1_k127_6038853_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000001693 150.0
HKD1_k127_6038853_2 - - - - 0.0000000000000000006587 90.0
HKD1_k127_6040920_0 Asparagine synthase K01953 - 6.3.5.4 2.704e-283 890.0
HKD1_k127_6040920_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 387.0
HKD1_k127_6050497_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 460.0
HKD1_k127_6050497_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
HKD1_k127_6050497_2 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 349.0
HKD1_k127_6050497_4 - - - - 0.0000000000000000000002569 109.0
HKD1_k127_6050497_5 START domain - - - 0.00000000000000000123 94.0
HKD1_k127_6053611_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 498.0
HKD1_k127_605430_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 420.0
HKD1_k127_605430_1 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 407.0
HKD1_k127_605430_2 Membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 352.0
HKD1_k127_605430_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 317.0
HKD1_k127_605430_4 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000004086 220.0
HKD1_k127_605430_5 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000009302 118.0
HKD1_k127_605430_6 HAMP domain K02482 - 2.7.13.3 0.0000001984 57.0
HKD1_k127_6055019_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.017e-250 786.0
HKD1_k127_6067603_0 repeat protein - - - 7.583e-202 642.0
HKD1_k127_6067603_1 RDD family K18481 - - 0.00000000000003408 76.0
HKD1_k127_6073192_0 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 390.0
HKD1_k127_6080209_0 Peptidase family M50 K11749 - - 6.56e-222 702.0
HKD1_k127_6080209_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 552.0
HKD1_k127_6080209_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003229 284.0
HKD1_k127_6080209_3 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000008004 211.0
HKD1_k127_6082616_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 443.0
HKD1_k127_6082616_1 penicillin-binding protein K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000002537 207.0
HKD1_k127_6082616_3 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000001928 98.0
HKD1_k127_6087276_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 598.0
HKD1_k127_6087276_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 574.0
HKD1_k127_6087276_2 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 365.0
HKD1_k127_6087276_3 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000794 199.0
HKD1_k127_6087276_4 Protein of unknown function (DUF4236) - - - 0.000000000001412 74.0
HKD1_k127_6087276_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00003329 51.0
HKD1_k127_6089228_0 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 323.0
HKD1_k127_6089228_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000001742 170.0
HKD1_k127_6089228_2 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000000000000001132 164.0
HKD1_k127_6091850_0 Homospermidine synthase K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 540.0
HKD1_k127_6091850_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000007316 197.0
HKD1_k127_6094666_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 5.79e-260 813.0
HKD1_k127_6094666_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 361.0
HKD1_k127_6094666_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002618 271.0
HKD1_k127_6094666_3 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000001569 130.0
HKD1_k127_6095454_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 4.18e-203 637.0
HKD1_k127_6095454_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 1.195e-199 628.0
HKD1_k127_6095454_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 556.0
HKD1_k127_6095454_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 399.0
HKD1_k127_6095454_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000003032 265.0
HKD1_k127_6116266_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 522.0
HKD1_k127_6116266_1 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000000001978 174.0
HKD1_k127_6116266_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000001436 147.0
HKD1_k127_6116266_3 gamma-glutamylcyclotransferase activity - - - 0.0000000000000000000000000000000002525 151.0
HKD1_k127_6116266_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000001438 120.0
HKD1_k127_6124223_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 389.0
HKD1_k127_6124223_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 387.0
HKD1_k127_6124223_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 284.0
HKD1_k127_6124223_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001532 258.0
HKD1_k127_6124223_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000001004 157.0
HKD1_k127_6124223_5 Universal stress protein - - - 0.00000000000000000000000001006 119.0
HKD1_k127_612548_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.888e-204 658.0
HKD1_k127_612548_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 475.0
HKD1_k127_612548_2 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 339.0
HKD1_k127_612548_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000004734 248.0
HKD1_k127_612548_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000002653 60.0
HKD1_k127_6130161_0 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 390.0
HKD1_k127_6130161_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000003026 213.0
HKD1_k127_6130161_2 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000001705 216.0
HKD1_k127_6130161_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000003155 170.0
HKD1_k127_6130611_0 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 475.0
HKD1_k127_6130611_1 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 382.0
HKD1_k127_6130611_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 300.0
HKD1_k127_6130611_3 Ferredoxin - - - 0.00000000000000000000000000000000000000000000004174 171.0
HKD1_k127_6130611_4 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000004901 170.0
HKD1_k127_6131943_0 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 561.0
HKD1_k127_6131943_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 372.0
HKD1_k127_6131943_2 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000001572 216.0
HKD1_k127_6131943_3 chemotaxis K02659,K03408 - - 0.0000000000000000000000000000000000004015 144.0
HKD1_k127_6131943_4 Histidine kinase - - - 0.0000000000000000000000000000006041 124.0
HKD1_k127_6131943_5 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000004575 98.0
HKD1_k127_6135671_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000003117 233.0
HKD1_k127_6135671_1 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000000000000000000000000000002705 200.0
HKD1_k127_6143772_0 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003228 275.0
HKD1_k127_6143772_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000133 294.0
HKD1_k127_6143772_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000002495 222.0
HKD1_k127_6143772_3 RDD family - - - 0.00000000000000000000000000007003 130.0
HKD1_k127_6143772_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000002012 69.0
HKD1_k127_6146730_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1072.0
HKD1_k127_6146730_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000001643 129.0
HKD1_k127_6147891_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 435.0
HKD1_k127_6147891_1 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 385.0
HKD1_k127_6147891_2 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 388.0
HKD1_k127_6147891_3 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000008542 199.0
HKD1_k127_6147891_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000002635 55.0
HKD1_k127_6149633_0 Proton-conducting membrane transporter K12141 - - 9.564e-221 692.0
HKD1_k127_6149633_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 2.209e-219 714.0
HKD1_k127_6149633_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 527.0
HKD1_k127_6149633_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 434.0
HKD1_k127_6149633_4 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 305.0
HKD1_k127_6149633_5 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000004007 241.0
HKD1_k127_6149633_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000002702 103.0
HKD1_k127_6151013_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 8.99e-242 754.0
HKD1_k127_6151013_1 Peptidase family M49 - - - 3.388e-207 655.0
HKD1_k127_6151013_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 426.0
HKD1_k127_6151013_3 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
HKD1_k127_6151013_4 FixH - - - 0.00000000000000000000000000000000000000000000001382 192.0
HKD1_k127_6151013_5 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.00000000000006125 79.0
HKD1_k127_6157743_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.064e-199 631.0
HKD1_k127_6157743_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 460.0
HKD1_k127_6157743_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 361.0
HKD1_k127_6157743_3 Alpha-amylase domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 362.0
HKD1_k127_6157743_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003125 263.0
HKD1_k127_6157743_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000003909 149.0
HKD1_k127_6168682_0 PFAM Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 592.0
HKD1_k127_6168682_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 364.0
HKD1_k127_6168682_2 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000001262 167.0
HKD1_k127_6170637_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 296.0
HKD1_k127_6170637_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000002111 193.0
HKD1_k127_6170637_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000004633 166.0
HKD1_k127_6180725_0 PFAM Uncharacterised protein family (UPF0236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 364.0
HKD1_k127_6190374_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 466.0
HKD1_k127_6190374_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 305.0
HKD1_k127_6199916_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 9.605e-215 678.0
HKD1_k127_6199916_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 556.0
HKD1_k127_6205872_0 WHG domain - - - 0.0000000000000000000000000000000002742 146.0
HKD1_k127_6205872_1 Belongs to the ompA family K03286 - - 0.0000001418 61.0
HKD1_k127_6212100_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 342.0
HKD1_k127_6212100_1 Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 290.0
HKD1_k127_6212100_2 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000003427 192.0
HKD1_k127_6212100_3 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000001943 89.0
HKD1_k127_6213478_0 transcription factor binding - - - 1.25e-223 720.0
HKD1_k127_6213478_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 531.0
HKD1_k127_6213478_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 297.0
HKD1_k127_6213478_3 - - - - 0.00000000000000000000000000000000000006826 147.0
HKD1_k127_6213478_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000004359 132.0
HKD1_k127_6213478_6 - - - - 0.0000000000000001299 83.0
HKD1_k127_6215831_0 penicillin-binding protein K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 508.0
HKD1_k127_6220660_0 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000002459 130.0
HKD1_k127_6225614_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000002955 63.0
HKD1_k127_6225614_1 peptidase U62, modulator of DNA gyrase K03568 - - 0.000006351 53.0
HKD1_k127_6237059_0 Phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 436.0
HKD1_k127_6237059_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 302.0
HKD1_k127_6239580_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 3.594e-199 623.0
HKD1_k127_6239580_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
HKD1_k127_6239580_2 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000000253 93.0
HKD1_k127_6243740_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1200.0
HKD1_k127_6243740_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000005276 256.0
HKD1_k127_6243740_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000008151 171.0
HKD1_k127_6246944_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.285e-278 891.0
HKD1_k127_6246944_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 350.0
HKD1_k127_6246944_2 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000001151 205.0
HKD1_k127_6249030_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 4.899e-283 884.0
HKD1_k127_6264032_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 3.664e-201 643.0
HKD1_k127_6264032_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 427.0
HKD1_k127_6265549_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001283 286.0
HKD1_k127_6265549_1 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005726 265.0
HKD1_k127_6265549_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009776 262.0
HKD1_k127_6266257_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.03e-205 650.0
HKD1_k127_6266257_1 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000001146 196.0
HKD1_k127_6268750_0 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 381.0
HKD1_k127_6268750_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000001296 155.0
HKD1_k127_6268750_2 Response regulator, receiver K03497 - - 0.0000000000000000000000003143 112.0
HKD1_k127_6283301_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 545.0
HKD1_k127_6283301_1 Alcohol dehydrogenase GroES domain protein K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 467.0
HKD1_k127_6283301_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000001979 198.0
HKD1_k127_6283301_3 PFAM Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000001738 148.0
HKD1_k127_6283301_5 Domain of unknown function (DUF4136) - - - 0.0002037 55.0
HKD1_k127_6284395_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 7.267e-253 788.0
HKD1_k127_6284395_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000001425 173.0
HKD1_k127_6293779_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000002625 232.0
HKD1_k127_6293779_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000004869 194.0
HKD1_k127_6302825_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 305.0
HKD1_k127_6302825_1 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000009067 246.0
HKD1_k127_6302825_2 Belongs to the HesB IscA family K13628 - - 0.000000000000000001287 89.0
HKD1_k127_6308979_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 1.072e-204 647.0
HKD1_k127_6308979_1 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 417.0
HKD1_k127_6308979_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000001651 228.0
HKD1_k127_6308979_3 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000000000000000000000001449 136.0
HKD1_k127_6308979_4 Methyltransferase domain - - - 0.000000000000000000000000006919 117.0
HKD1_k127_6308979_5 Mannosyltransferase (PIG-V) - - - 0.0000000000000000000000001807 115.0
HKD1_k127_6309925_0 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 473.0
HKD1_k127_6309925_1 Glycosyl transferases group 1 K16703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 480.0
HKD1_k127_6309925_2 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 449.0
HKD1_k127_6309925_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 349.0
HKD1_k127_6309925_4 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 323.0
HKD1_k127_6309925_5 extracellular polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000003154 223.0
HKD1_k127_6309925_6 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000003772 133.0
HKD1_k127_6309925_7 - - - - 0.00000000000008681 78.0
HKD1_k127_6321272_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000001959 214.0
HKD1_k127_6321272_1 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000001795 195.0
HKD1_k127_6321272_2 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000000000000000008982 150.0
HKD1_k127_6322897_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 526.0
HKD1_k127_6322897_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 413.0
HKD1_k127_6322897_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 311.0
HKD1_k127_6322897_3 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000305 111.0
HKD1_k127_6332483_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1066.0
HKD1_k127_6332483_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.000000000000000000000000000000000000000000000000000000003719 203.0
HKD1_k127_6335436_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 482.0
HKD1_k127_6335436_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 351.0
HKD1_k127_6342248_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 3.131e-295 946.0
HKD1_k127_6342248_1 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 6.185e-290 900.0
HKD1_k127_6342248_2 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000005289 143.0
HKD1_k127_6342248_3 Signal peptidase (SPase) II - - - 0.0000000000000000000000002916 112.0
HKD1_k127_6342248_4 Protein of unknown function (DUF4242) - - - 0.000000000000000000000006778 102.0
HKD1_k127_6342742_0 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 367.0
HKD1_k127_6342742_1 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000001897 217.0
HKD1_k127_6342742_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000002475 149.0
HKD1_k127_6343830_0 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 411.0
HKD1_k127_6353949_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1371.0
HKD1_k127_6353949_1 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004017 285.0
HKD1_k127_6353949_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000006821 187.0
HKD1_k127_6354401_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 598.0
HKD1_k127_6354401_1 Protein export membrane protein K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 391.0
HKD1_k127_6356667_0 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000002052 125.0
HKD1_k127_6358696_1 Response regulator, receiver K03497 - - 0.00000000000000000000000000000000000000000000000000002319 192.0
HKD1_k127_6361852_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000009036 62.0
HKD1_k127_6361988_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 533.0
HKD1_k127_6361988_1 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 370.0
HKD1_k127_6361988_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
HKD1_k127_6361988_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001617 249.0
HKD1_k127_6361988_4 WD40-like Beta Propeller Repeat - - - 0.00000000003085 76.0
HKD1_k127_6362192_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 327.0
HKD1_k127_6362192_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000005889 181.0
HKD1_k127_6362192_2 Bile acid K03453 - - 0.000000000000000000000000000000000000001434 158.0
HKD1_k127_6362192_3 membrane - - - 0.00000000000000000000000000002056 124.0
HKD1_k127_6369062_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 490.0
HKD1_k127_6369062_1 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000002678 151.0
HKD1_k127_6369062_2 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000002564 82.0
HKD1_k127_6378925_0 Insulinase (Peptidase family M16) K07263 - - 2.005e-280 879.0
HKD1_k127_6383843_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 329.0
HKD1_k127_6383843_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000004489 169.0
HKD1_k127_6386584_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000001143 145.0
HKD1_k127_6392718_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 419.0
HKD1_k127_6392718_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000002315 252.0
HKD1_k127_6392718_2 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000004088 212.0
HKD1_k127_6392718_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000003489 154.0
HKD1_k127_6392718_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000002988 108.0
HKD1_k127_6392718_5 Domain of unknown function (DUF4340) - - - 0.0008845 53.0
HKD1_k127_6394335_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 8.386e-284 890.0
HKD1_k127_6394335_1 Bacterial protein of unknown function (DUF853) K06915 - - 3.18e-203 644.0
HKD1_k127_6394335_2 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008306 301.0
HKD1_k127_6394335_3 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.0000000000000000000000000000000000000000000000000007443 190.0
HKD1_k127_6394335_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000003502 72.0
HKD1_k127_6394404_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 359.0
HKD1_k127_6394404_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000323 233.0
HKD1_k127_6394404_2 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000183 226.0
HKD1_k127_6394404_4 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00002165 56.0
HKD1_k127_6403035_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 532.0
HKD1_k127_6403035_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 511.0
HKD1_k127_6415521_0 Sarcosine oxidase K00303 - 1.5.3.1 4.279e-220 712.0
HKD1_k127_6415521_1 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 456.0
HKD1_k127_6415521_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 398.0
HKD1_k127_6415521_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 380.0
HKD1_k127_6415521_4 peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000002634 99.0
HKD1_k127_6424295_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 352.0
HKD1_k127_6424295_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 333.0
HKD1_k127_6424295_2 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000000000001497 151.0
HKD1_k127_6424295_3 domain, Protein - - - 0.000000000000000000000005454 113.0
HKD1_k127_6449735_0 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002824 277.0
HKD1_k127_6453816_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000396 280.0
HKD1_k127_6453816_1 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000005822 223.0
HKD1_k127_6453816_2 Sulphur transport K07112 - - 0.000000004107 57.0
HKD1_k127_6467341_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 607.0
HKD1_k127_6467341_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 447.0
HKD1_k127_6467341_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 327.0
HKD1_k127_6467341_3 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 308.0
HKD1_k127_6467341_4 - - - - 0.000000000000000000000000000000000000002827 156.0
HKD1_k127_6467341_5 - - - - 0.0000000000000000000000000000001312 134.0
HKD1_k127_6467341_6 peptide catabolic process K01256 - 3.4.11.2 0.00000000000000000000000000005604 122.0
HKD1_k127_6467341_7 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000186 131.0
HKD1_k127_6515871_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000007058 190.0
HKD1_k127_6515871_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000007963 83.0
HKD1_k127_6515871_2 - - - - 0.00000000000000002849 94.0
HKD1_k127_6519176_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 486.0
HKD1_k127_6519176_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000001472 187.0
HKD1_k127_6519554_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1513.0
HKD1_k127_6519554_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 460.0
HKD1_k127_6519554_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 391.0
HKD1_k127_6519554_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000004584 198.0
HKD1_k127_6519554_4 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000002543 107.0
HKD1_k127_6529071_0 AAA domain K10742 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 469.0
HKD1_k127_6529071_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000106 265.0
HKD1_k127_6529071_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000003042 120.0
HKD1_k127_6529853_0 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000003381 186.0
HKD1_k127_6529853_1 Peptide transporter - - - 0.0000000000000000000000000000000000000006445 153.0
HKD1_k127_6533839_0 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 574.0
HKD1_k127_6533839_1 Pfam:DUF955 K07110 - - 0.00000000000000000000000000000000000000000000000000000000006176 205.0
HKD1_k127_6540692_0 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 434.0
HKD1_k127_6540692_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000004327 163.0
HKD1_k127_6540692_2 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000006665 143.0
HKD1_k127_6548533_1 Spore Coat Protein U domain - - - 0.000000000000000006675 91.0
HKD1_k127_6548533_2 Pfam Spore Coat Protein U - - - 0.000000000000008819 84.0
HKD1_k127_6551475_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 424.0
HKD1_k127_6551475_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 379.0
HKD1_k127_6551475_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 286.0
HKD1_k127_6551475_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000149 248.0
HKD1_k127_6551475_4 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000008461 213.0
HKD1_k127_6551475_5 - - - - 0.000000000000000000000000005504 124.0
HKD1_k127_6552749_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 513.0
HKD1_k127_6552749_1 CBS domain containing protein K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 400.0
HKD1_k127_6552749_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 297.0
HKD1_k127_6552749_3 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
HKD1_k127_6552749_4 PFAM YCII-related - - - 0.00000000000000000000000000000000001041 138.0
HKD1_k127_6552749_6 Hydrogenase maturation protease - - - 0.0000002539 61.0
HKD1_k127_6565079_0 DNA restriction-modification system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 311.0
HKD1_k127_6565079_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000005039 256.0
HKD1_k127_6576331_0 diguanylate cyclase - - - 4.399e-201 650.0
HKD1_k127_6576331_1 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000001799 85.0
HKD1_k127_6578744_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 3.38e-228 734.0
HKD1_k127_6578744_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000001455 62.0
HKD1_k127_6579105_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000003405 183.0
HKD1_k127_6579105_1 Response regulator receiver domain - - - 0.00000000000000003072 94.0
HKD1_k127_6603288_0 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 550.0
HKD1_k127_6603288_1 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004459 278.0
HKD1_k127_6603288_2 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000001147 265.0
HKD1_k127_6603288_3 PFAM Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000005888 160.0
HKD1_k127_6603288_4 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000001091 128.0
HKD1_k127_6623603_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 4.329e-200 632.0
HKD1_k127_6623603_1 integral membrane protein - - - 0.000000000000000000003699 105.0
HKD1_k127_6633061_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 370.0
HKD1_k127_6633061_1 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000001184 226.0
HKD1_k127_6633061_2 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000009697 177.0
HKD1_k127_6642062_0 Pfam:Kce K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 409.0
HKD1_k127_6642062_1 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 394.0
HKD1_k127_6642062_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000128 240.0
HKD1_k127_6642062_3 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000000000000000000000000003183 226.0
HKD1_k127_6642062_6 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.0000002077 52.0
HKD1_k127_6651120_0 Elongation factor G, domain IV K02355 - - 0.0 1052.0
HKD1_k127_6651120_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 436.0
HKD1_k127_6651120_2 GyrI-like small molecule binding domain - - - 0.0000000000000000006966 91.0
HKD1_k127_665640_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 8.238e-196 622.0
HKD1_k127_665640_1 PFAM aminotransferase class I and II K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 568.0
HKD1_k127_665640_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 381.0
HKD1_k127_665640_3 nuclear chromosome segregation K13582,K21471 - - 0.000000000000000000000000000000000000000000000000000000508 213.0
HKD1_k127_6657562_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 541.0
HKD1_k127_6657562_1 UvrD/REP helicase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 326.0
HKD1_k127_6665656_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 372.0
HKD1_k127_6665656_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 307.0
HKD1_k127_6665656_2 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HKD1_k127_6665656_3 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000001093 176.0
HKD1_k127_6667373_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 424.0
HKD1_k127_6667373_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004183 291.0
HKD1_k127_6667373_2 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0000000000000000000000000000000000000000000000000000000000007708 227.0
HKD1_k127_6670767_0 Aspartate ammonia-lyase K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 384.0
HKD1_k127_6670767_1 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000001334 149.0
HKD1_k127_6670767_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000001564 115.0
HKD1_k127_6670767_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000004829 69.0
HKD1_k127_6677387_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 462.0
HKD1_k127_6677387_1 Diadenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 377.0
HKD1_k127_6677387_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000495 261.0
HKD1_k127_6677387_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000009211 203.0
HKD1_k127_6677489_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 350.0
HKD1_k127_6677489_1 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 297.0
HKD1_k127_6677489_2 Response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000000008811 162.0
HKD1_k127_6681452_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 432.0
HKD1_k127_6681452_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 410.0
HKD1_k127_6681452_2 PFAM Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000005162 233.0
HKD1_k127_6681452_3 YtxH-like protein - - - 0.0002042 51.0
HKD1_k127_6685938_0 RNA polymerase recycling family C-terminal K03580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 522.0
HKD1_k127_6685938_1 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 522.0
HKD1_k127_6685938_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 499.0
HKD1_k127_6685938_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 384.0
HKD1_k127_6685938_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000001337 171.0
HKD1_k127_6694836_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 611.0
HKD1_k127_6694836_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 598.0
HKD1_k127_669587_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 404.0
HKD1_k127_669587_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000001545 231.0
HKD1_k127_6713551_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.236e-222 696.0
HKD1_k127_6713551_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 506.0
HKD1_k127_6713551_2 PFAM Phosphate acetyl butaryl transferase K00634 - 2.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 351.0
HKD1_k127_6713551_3 COG1073 hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000005978 178.0
HKD1_k127_6713551_4 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000516 175.0
HKD1_k127_6713551_5 Belongs to the acetokinase family K00929 - 2.7.2.7 0.000000000001577 75.0
HKD1_k127_6713576_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 476.0
HKD1_k127_6713576_1 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 489.0
HKD1_k127_6713576_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 451.0
HKD1_k127_6713576_3 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 327.0
HKD1_k127_6713576_4 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 293.0
HKD1_k127_6713576_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000003611 207.0
HKD1_k127_6713576_6 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000001182 183.0
HKD1_k127_6715234_0 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 528.0
HKD1_k127_6715234_1 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 408.0
HKD1_k127_6715234_2 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 398.0
HKD1_k127_6715234_3 nickel cation binding K04651 - - 0.00000000000000000000000000000000003383 137.0
HKD1_k127_6715234_4 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000009045 106.0
HKD1_k127_6715808_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 543.0
HKD1_k127_6715808_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 302.0
HKD1_k127_6715808_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 310.0
HKD1_k127_6718508_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 535.0
HKD1_k127_6718508_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 496.0
HKD1_k127_6718508_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 435.0
HKD1_k127_6718508_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 383.0
HKD1_k127_6718508_4 polysaccharide catabolic process K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000001065 234.0
HKD1_k127_6718508_5 - - - - 0.0000000000000000000000000002316 130.0
HKD1_k127_6722521_0 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000001127 185.0
HKD1_k127_6722521_1 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000003993 172.0
HKD1_k127_6722521_2 Belongs to the UPF0434 family K09791 - - 0.000000000000000000001274 94.0
HKD1_k127_6723176_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 472.0
HKD1_k127_6723176_1 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000573 237.0
HKD1_k127_6723176_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000004 119.0
HKD1_k127_6723176_3 - K07018 - - 0.0000000000000000279 91.0
HKD1_k127_6743338_0 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 430.0
HKD1_k127_6743338_1 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000002382 124.0
HKD1_k127_6743338_2 - K07112 - - 0.0000000000005005 71.0
HKD1_k127_6747598_0 WYL domain K13573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 489.0
HKD1_k127_6747598_1 regulation of single-species biofilm formation K13572,K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 460.0
HKD1_k127_6747598_3 Protein of unknown function (DUF1054) - - - 0.00000000000000000000000000000000000000000000000000000001058 206.0
HKD1_k127_6752486_0 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 555.0
HKD1_k127_6752486_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 394.0
HKD1_k127_6769744_0 peptidase U62 modulator of DNA gyrase - - - 9.718e-223 702.0
HKD1_k127_6786564_0 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 447.0
HKD1_k127_6786564_1 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000004069 260.0
HKD1_k127_6790642_0 PFAM Prolyl oligopeptidase family - - - 3.638e-240 765.0
HKD1_k127_6790642_1 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 344.0
HKD1_k127_6790642_2 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000005628 180.0
HKD1_k127_6790642_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000005702 51.0
HKD1_k127_6806761_0 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 394.0
HKD1_k127_6806761_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 349.0
HKD1_k127_6806761_2 anaerobic c4-dicarboxylate K07791,K07792 - - 0.00000000001199 68.0
HKD1_k127_6816759_0 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 288.0
HKD1_k127_6816759_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000002276 227.0
HKD1_k127_6816759_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00007884 45.0
HKD1_k127_6819291_0 UvrD/REP helicase N-terminal domain - - - 1.668e-267 846.0
HKD1_k127_6819291_1 Methyltransferase domain - - - 0.0000000000000000000000000000002362 126.0
HKD1_k127_6850725_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 7.179e-239 749.0
HKD1_k127_6854194_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.236e-259 816.0
HKD1_k127_6854194_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 514.0
HKD1_k127_6854194_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 323.0
HKD1_k127_6854194_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009157 260.0
HKD1_k127_6854194_4 Outer membrane efflux protein - - - 0.000000000000000000000005469 118.0
HKD1_k127_6868140_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 306.0
HKD1_k127_6868140_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
HKD1_k127_6868140_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002188 252.0
HKD1_k127_6871341_0 DNA recombination protein RmuC K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 392.0
HKD1_k127_6871341_1 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000009825 138.0
HKD1_k127_6881883_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 1.478e-219 689.0
HKD1_k127_6881883_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00002507 46.0
HKD1_k127_6881910_0 DNA polymerase III, delta' K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 474.0
HKD1_k127_6881910_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000001138 173.0
HKD1_k127_6905189_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 571.0
HKD1_k127_6911233_0 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000001666 206.0
HKD1_k127_6911233_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000003486 198.0
HKD1_k127_6911233_2 Diacylglycerol kinase catalytic domain - - - 0.0002429 45.0
HKD1_k127_6919668_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 1.638e-215 702.0
HKD1_k127_6919668_1 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 481.0
HKD1_k127_6919668_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 376.0
HKD1_k127_6923174_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 530.0
HKD1_k127_6923174_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 476.0
HKD1_k127_6923174_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 346.0
HKD1_k127_692771_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
HKD1_k127_692771_1 Glycerophosphoryl diester phosphodiesterase family - - - 0.0000000000000000000000000001334 132.0
HKD1_k127_692771_2 Calcineurin-like phosphoesterase - - - 0.00000000008254 74.0
HKD1_k127_69298_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 552.0
HKD1_k127_69298_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000001634 141.0
HKD1_k127_69298_2 GDP-mannose 4,6 dehydratase K01711 - 4.2.1.47 0.00000000000000000115 101.0
HKD1_k127_6935096_0 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006957 249.0
HKD1_k127_6935096_1 Cysteine-rich domain K00113 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
HKD1_k127_6935096_2 transmembrane signaling receptor activity K03406 - - 0.0000000000000000000000000000000002311 145.0
HKD1_k127_6935096_3 - - - - 0.000000000000000000000000000000002501 134.0
HKD1_k127_6935096_4 Type II/IV secretion system protein K02669 - - 0.0000000000000005779 83.0
HKD1_k127_6967676_0 alpha amylase, catalytic region - - - 1.053e-227 716.0
HKD1_k127_6967676_1 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002338 247.0
HKD1_k127_6967676_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 247.0
HKD1_k127_6967676_3 translation initiation factor activity - - - 0.0000000000000000000000000006443 120.0
HKD1_k127_6981038_0 Putative amidoligase enzyme (DUF2126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 349.0
HKD1_k127_6981038_1 Putative amidoligase enzyme (DUF2126) - - - 0.0000000000000000000000000000000002018 134.0
HKD1_k127_6996766_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 556.0
HKD1_k127_6996766_1 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 345.0
HKD1_k127_6996766_2 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 339.0
HKD1_k127_6996766_3 SNARE associated Golgi protein - - - 0.000000000000000000000000001474 125.0
HKD1_k127_6998698_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 613.0
HKD1_k127_6998698_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 391.0
HKD1_k127_7016381_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 568.0
HKD1_k127_7016381_1 membrane - - - 0.0000000000000000037 90.0
HKD1_k127_7022077_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 486.0
HKD1_k127_7022077_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 478.0
HKD1_k127_7022077_2 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000155 160.0
HKD1_k127_703531_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 450.0
HKD1_k127_703531_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 423.0
HKD1_k127_703531_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 327.0
HKD1_k127_703531_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000003305 230.0
HKD1_k127_703531_4 translation initiation factor activity K06996 - - 0.000000000000000000000000000000002098 146.0
HKD1_k127_7040856_0 Protein of unknown function (DUF1254) - - - 1.438e-210 666.0
HKD1_k127_7040856_1 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000002961 66.0
HKD1_k127_7042567_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.501e-229 718.0
HKD1_k127_7042567_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 490.0
HKD1_k127_7042567_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 299.0
HKD1_k127_7042567_3 negative regulation of translational initiation - - - 0.000000000000000000000000000000000000000000000000000000001663 203.0
HKD1_k127_7042567_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000008615 86.0
HKD1_k127_7042567_5 - - - - 0.0000001514 56.0
HKD1_k127_7045790_0 Methionine synthase K00548 - 2.1.1.13 0.0 1187.0
HKD1_k127_7046874_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 589.0
HKD1_k127_7046874_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 368.0
HKD1_k127_7046874_2 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 302.0
HKD1_k127_7046874_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 300.0
HKD1_k127_7046874_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000001487 175.0
HKD1_k127_7046874_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000005411 115.0
HKD1_k127_7054080_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 401.0
HKD1_k127_7054080_1 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 363.0
HKD1_k127_7054080_2 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
HKD1_k127_7054080_3 Universal stress protein family - - - 0.000000000000000000000000000000000000000001048 164.0
HKD1_k127_7065568_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 525.0
HKD1_k127_7065568_1 - - - - 0.000000000000000008229 89.0
HKD1_k127_7065568_2 Zinc-dependent metalloprotease - - - 0.000000003083 70.0
HKD1_k127_7073758_0 4 iron, 4 sulfur cluster binding K02573 - - 0.000000000000000000000000000000000000000002006 165.0
HKD1_k127_7073758_1 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.000000000000000000000000000000000000005249 146.0
HKD1_k127_7073758_3 4Fe-4S binding domain K02574 - - 0.000000000000000000062 104.0
HKD1_k127_7073758_4 Belongs to the nlpA lipoprotein family K02073 - - 0.00001677 57.0
HKD1_k127_7075067_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 383.0
HKD1_k127_7075067_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001493 232.0
HKD1_k127_7076395_0 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 7e-323 994.0
HKD1_k127_7076395_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000003361 247.0
HKD1_k127_7076395_2 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000001009 166.0
HKD1_k127_708839_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.168e-220 691.0
HKD1_k127_708839_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 359.0
HKD1_k127_708839_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000003811 152.0
HKD1_k127_71002_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 419.0
HKD1_k127_71002_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000471 172.0
HKD1_k127_71002_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000003187 87.0
HKD1_k127_710668_0 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006174 263.0
HKD1_k127_710668_1 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000008152 237.0
HKD1_k127_710668_2 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000000000000000000003771 211.0
HKD1_k127_7122011_0 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 545.0
HKD1_k127_7122011_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 338.0
HKD1_k127_7127019_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 511.0
HKD1_k127_7127019_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000009647 188.0
HKD1_k127_7134659_0 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 509.0
HKD1_k127_7134659_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000001799 178.0
HKD1_k127_7134659_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000006725 167.0
HKD1_k127_7136268_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 340.0
HKD1_k127_7136268_1 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 341.0
HKD1_k127_7137232_0 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 400.0
HKD1_k127_7137232_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 375.0
HKD1_k127_7137232_2 Domain of unknown function (DUF1794) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 308.0
HKD1_k127_7137232_3 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000007144 72.0
HKD1_k127_7147105_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0 1154.0
HKD1_k127_7147105_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 317.0
HKD1_k127_7147105_2 Cytochrome P460 - - - 0.000000000000000000009531 104.0
HKD1_k127_7147105_3 Polymer-forming cytoskeletal - - - 0.00005869 48.0
HKD1_k127_7148228_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 294.0
HKD1_k127_7148228_1 Periplasmic protein TonB links inner and outer membranes - - - 0.000000000000000000000000000000000000000000000000000000000000000000004196 247.0
HKD1_k127_7162084_0 Belongs to the ClpA ClpB family K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 508.0
HKD1_k127_7162084_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 340.0
HKD1_k127_7162084_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
HKD1_k127_7162084_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000004014 142.0
HKD1_k127_7163136_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 413.0
HKD1_k127_7163136_1 hydrolase activity, acting on ester bonds K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 257.0
HKD1_k127_7163136_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000003882 210.0
HKD1_k127_7163136_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000005501 210.0
HKD1_k127_7177838_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1091.0
HKD1_k127_7177838_1 zinc ion binding K06204 - - 0.00000000000000002255 88.0
HKD1_k127_7177838_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000002124 53.0
HKD1_k127_7180875_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 399.0
HKD1_k127_7180875_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004826 255.0
HKD1_k127_7180875_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001495 275.0
HKD1_k127_7184913_0 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 310.0
HKD1_k127_7184913_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004895 281.0
HKD1_k127_7184913_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000006741 242.0
HKD1_k127_7184913_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000001058 169.0
HKD1_k127_7184913_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000005093 179.0
HKD1_k127_7210260_0 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
HKD1_k127_7210260_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000003209 207.0
HKD1_k127_7210260_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001303 200.0
HKD1_k127_7210260_3 sequence-specific DNA binding - - - 0.00000000000000000266 84.0
HKD1_k127_7219558_0 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 548.0
HKD1_k127_7219558_1 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 261.0
HKD1_k127_7219558_2 Type II secretion system (T2SS), protein M subtype b K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001711 248.0
HKD1_k127_7219558_3 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000000002087 217.0
HKD1_k127_7219558_4 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000003128 190.0
HKD1_k127_7219558_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000007935 104.0
HKD1_k127_7219558_6 response regulator K07714 - - 0.000000000000000001857 86.0
HKD1_k127_7223189_0 PFAM AMP-dependent synthetase and ligase - - - 0.0 1143.0
HKD1_k127_7223189_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 629.0
HKD1_k127_7223189_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 301.0
HKD1_k127_7223189_3 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000002514 145.0
HKD1_k127_7234233_0 P-loop containing region of AAA domain K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 554.0
HKD1_k127_7234233_1 protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 456.0
HKD1_k127_7234233_2 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000002045 201.0
HKD1_k127_7234233_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000003367 154.0
HKD1_k127_7234233_4 - - - - 0.00000000000000000000000000001286 128.0
HKD1_k127_7235653_0 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 373.0
HKD1_k127_7235653_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 355.0
HKD1_k127_7235653_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000131 186.0
HKD1_k127_7235653_3 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000005368 164.0
HKD1_k127_7235653_5 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.00003267 55.0
HKD1_k127_7239557_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 369.0
HKD1_k127_7239557_1 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001153 286.0
HKD1_k127_7239557_2 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000002 201.0
HKD1_k127_7240858_0 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 544.0
HKD1_k127_7240858_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 507.0
HKD1_k127_7240858_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 321.0
HKD1_k127_7240858_3 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000008209 180.0
HKD1_k127_7253000_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 363.0
HKD1_k127_7253000_1 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 343.0
HKD1_k127_7253000_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001071 264.0
HKD1_k127_7253000_3 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000005209 179.0
HKD1_k127_7253000_4 - - - - 0.00000000000000000000000000000000000005345 151.0
HKD1_k127_7253000_5 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000001202 63.0
HKD1_k127_7253000_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00001516 49.0
HKD1_k127_7258724_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000003862 214.0
HKD1_k127_7258724_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000008227 209.0
HKD1_k127_7258724_2 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000004368 186.0
HKD1_k127_7258724_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000004033 132.0
HKD1_k127_726114_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 5.132e-297 921.0
HKD1_k127_726114_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 438.0
HKD1_k127_726114_2 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 419.0
HKD1_k127_726114_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 410.0
HKD1_k127_726114_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001823 230.0
HKD1_k127_726114_5 regulation of translation K03530 - - 0.0000000000000000000000000000000002139 136.0
HKD1_k127_726122_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 450.0
HKD1_k127_726122_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 463.0
HKD1_k127_726122_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 294.0
HKD1_k127_726122_3 protein trimerization K15368 - - 0.00000000000000000000000000000000000000000001632 185.0
HKD1_k127_7261659_0 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 392.0
HKD1_k127_7261659_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000005639 167.0
HKD1_k127_7277791_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 492.0
HKD1_k127_7277791_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 360.0
HKD1_k127_7277791_2 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000004521 199.0
HKD1_k127_7290170_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 549.0
HKD1_k127_7290170_1 Acyltransferase family - - - 0.0000000000000000005698 88.0
HKD1_k127_7290170_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000007847 58.0
HKD1_k127_7302027_0 Transglycosylase K05367 - 2.4.1.129 3.551e-272 857.0
HKD1_k127_7302027_1 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000004049 106.0
HKD1_k127_7302125_0 DUF1704 - - - 1.382e-200 630.0
HKD1_k127_7302125_1 VIT family - - - 0.000000000000000000000000000000000000000002719 158.0
HKD1_k127_730290_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 606.0
HKD1_k127_730290_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 474.0
HKD1_k127_730290_2 pseudouridine synthase activity K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000004528 214.0
HKD1_k127_7330400_0 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 550.0
HKD1_k127_7330400_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 348.0
HKD1_k127_7330400_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004843 296.0
HKD1_k127_7330400_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000002106 218.0
HKD1_k127_7330400_4 NUDIX domain - - - 0.00000000000000000000000000000005979 141.0
HKD1_k127_7330400_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000002437 116.0
HKD1_k127_7336886_0 Flavin containing amine oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 382.0
HKD1_k127_7336886_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000002869 212.0
HKD1_k127_7336886_2 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.0001175 53.0
HKD1_k127_7342355_0 Selenocysteine-specific translation elongation factor K03833 - - 3.217e-294 914.0
HKD1_k127_7342355_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 460.0
HKD1_k127_7342355_2 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 449.0
HKD1_k127_7342355_3 Hsp33 protein K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 349.0
HKD1_k127_7342355_4 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002001 279.0
HKD1_k127_7342355_5 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000001826 205.0
HKD1_k127_7344957_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 563.0
HKD1_k127_7344957_1 R3H domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000008624 220.0
HKD1_k127_7344957_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000001946 120.0
HKD1_k127_7344957_3 - - - - 0.0000000005667 62.0
HKD1_k127_7348083_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 436.0
HKD1_k127_7348083_1 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000004433 207.0
HKD1_k127_7348083_2 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000000000000001127 146.0
HKD1_k127_7353757_0 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000009598 244.0
HKD1_k127_7360105_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 428.0
HKD1_k127_7360105_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000002103 263.0
HKD1_k127_7360105_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000176 44.0
HKD1_k127_7363826_0 TIR domain - - - 0.00000000000000000000000000000000008253 145.0
HKD1_k127_7363826_1 protein kinase activity - - - 0.0000000000000000000000000001717 118.0
HKD1_k127_7369118_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 397.0
HKD1_k127_7369118_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 390.0
HKD1_k127_7369118_2 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000001215 220.0
HKD1_k127_7386351_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 556.0
HKD1_k127_7386351_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000203 233.0
HKD1_k127_7386351_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000095 169.0
HKD1_k127_7386351_3 Protein of unknown function (DUF2470) K07226 - - 0.000000000000000000000000003296 125.0
HKD1_k127_7386351_4 Metallo-beta-lactamase superfamily - - - 0.00000000002241 76.0
HKD1_k127_7391037_0 - - - - 0.000000000000000000000000000000000000000000000003531 191.0
HKD1_k127_7391037_1 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000001614 155.0
HKD1_k127_7391037_2 HD domain - - - 0.000000000000000000000000000001104 126.0
HKD1_k127_7391037_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000004043 120.0
HKD1_k127_7391037_4 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0003497 47.0
HKD1_k127_7407378_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 419.0
HKD1_k127_7407378_1 CAAX protease self-immunity - - - 0.000000000000000000000000000000000002311 150.0
HKD1_k127_7407378_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000007717 63.0
HKD1_k127_7424045_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 496.0
HKD1_k127_7424045_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 432.0
HKD1_k127_7424045_2 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 416.0
HKD1_k127_7424045_3 response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001413 271.0
HKD1_k127_7424045_4 response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000254 258.0
HKD1_k127_7424045_5 glycoside hydrolase family 57 K16149 - 2.4.1.18 0.0000000000000000000000000000000000001365 143.0
HKD1_k127_7431217_0 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 536.0
HKD1_k127_7431217_2 Pfam:DUF955 K07110 - - 0.000000000000000000000000000000000000002574 149.0
HKD1_k127_7431217_3 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000002217 83.0
HKD1_k127_7431274_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 441.0
HKD1_k127_7431274_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 413.0
HKD1_k127_7431274_2 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 299.0
HKD1_k127_7431274_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000004063 69.0
HKD1_k127_743365_0 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 1.003e-258 811.0
HKD1_k127_743365_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 374.0
HKD1_k127_743365_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000002367 169.0
HKD1_k127_7442446_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 377.0
HKD1_k127_7442446_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 346.0
HKD1_k127_7442446_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 322.0
HKD1_k127_7442446_3 transglycosylase K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
HKD1_k127_7454351_0 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 299.0
HKD1_k127_7454351_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008830,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000866 277.0
HKD1_k127_7454351_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000341 256.0
HKD1_k127_7454351_3 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000005839 140.0
HKD1_k127_7454351_4 Phosphopantetheine attachment site - - - 0.0000000000000000000000002377 116.0
HKD1_k127_7454444_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000001448 201.0
HKD1_k127_7454444_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001462 168.0
HKD1_k127_7454444_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000001575 144.0
HKD1_k127_7454444_3 Belongs to the peptidase S33 family - - - 0.000000000000002895 83.0
HKD1_k127_7457688_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001292 268.0
HKD1_k127_7457688_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000001835 205.0
HKD1_k127_7467773_0 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 452.0
HKD1_k127_7467773_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000001403 210.0
HKD1_k127_7473971_0 SMART Elongator protein 3 MiaB NifB - - - 1.032e-199 633.0
HKD1_k127_7473971_1 PFAM MMPL family K07003 - - 0.000000000000000000001565 98.0
HKD1_k127_7493856_0 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000006457 237.0
HKD1_k127_7493856_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000104 170.0
HKD1_k127_7493856_2 - - - - 0.000000000000000000002892 103.0
HKD1_k127_7510476_0 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 379.0
HKD1_k127_7510476_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 291.0
HKD1_k127_7510476_2 organic acid phosphorylation K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
HKD1_k127_7510476_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000005312 216.0
HKD1_k127_7523322_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 498.0
HKD1_k127_7523322_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 417.0
HKD1_k127_7523322_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001338 217.0
HKD1_k127_7523322_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000005374 216.0
HKD1_k127_7523322_4 HI0933-like protein - - - 0.00000000000000000000000000000000000001238 146.0
HKD1_k127_7523322_5 MgtE intracellular - - - 0.0000000000000000000000000000000000003384 147.0
HKD1_k127_7523322_6 - - - - 0.000000000000005058 90.0
HKD1_k127_7526585_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000338 304.0
HKD1_k127_7526585_1 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000435 288.0
HKD1_k127_7526585_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000001138 254.0
HKD1_k127_7526585_3 Predicted Zn-dependent protease (DUF2268) - - - 0.0000000000000000000000000000000000000000000000000000003836 204.0
HKD1_k127_7526585_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000001221 199.0
HKD1_k127_7533416_0 lipopolysaccharide transport K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 552.0
HKD1_k127_7533416_1 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000003844 240.0
HKD1_k127_7533416_2 translation initiation factor activity - - - 0.0000000000000000000000000000001404 128.0
HKD1_k127_7534542_0 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 469.0
HKD1_k127_7543553_0 PFAM Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000001702 228.0
HKD1_k127_7543553_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000007538 139.0
HKD1_k127_7544005_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 534.0
HKD1_k127_7544005_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 479.0
HKD1_k127_7544005_2 HD domain K07814 - - 0.000000000000005965 81.0
HKD1_k127_7546660_0 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 354.0
HKD1_k127_7546660_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - - 0.0000000000000000000000000000000000000000000001068 171.0
HKD1_k127_7546660_2 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000002884 98.0
HKD1_k127_7548703_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 361.0
HKD1_k127_7548703_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000008364 172.0
HKD1_k127_7548703_2 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000001603 151.0
HKD1_k127_7548703_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000004613 141.0
HKD1_k127_7550350_0 PFAM sulfatase K01130 - 3.1.6.1 4.009e-241 755.0
HKD1_k127_7580132_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.694e-319 1020.0
HKD1_k127_7580132_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 2.036e-259 811.0
HKD1_k127_7580132_2 Bacterial regulatory protein, Fis family K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 595.0
HKD1_k127_7580132_3 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 593.0
HKD1_k127_7580132_4 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 512.0
HKD1_k127_7580132_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000001553 234.0
HKD1_k127_7580132_6 - - - - 0.000000001957 68.0
HKD1_k127_7592604_0 Endothelin-converting enzyme K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 334.0
HKD1_k127_7592604_1 phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 325.0
HKD1_k127_7592604_2 Beta propeller domain - - - 0.000000002089 69.0
HKD1_k127_7607825_0 radical SAM domain protein - - - 5.329e-202 637.0
HKD1_k127_7607825_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 617.0
HKD1_k127_7607825_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002029 299.0
HKD1_k127_7607825_3 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
HKD1_k127_7607825_4 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000003334 158.0
HKD1_k127_7607825_5 Serine aminopeptidase, S33 K07018 - - 0.00006545 55.0
HKD1_k127_7609178_0 Peptidase family M1 domain - - - 5.838e-218 698.0
HKD1_k127_7609178_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000003346 244.0
HKD1_k127_7609809_0 Tetratricopeptide repeat - - - 2.12e-282 889.0
HKD1_k127_7609809_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 571.0
HKD1_k127_762626_0 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000000000001188 128.0
HKD1_k127_762626_1 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000002061 139.0
HKD1_k127_762626_2 nitrogen fixation - - - 0.0000000000000000000000000002033 133.0
HKD1_k127_762626_3 rhodanese-related sulfurtransferase - - - 0.00000003048 61.0
HKD1_k127_7628902_0 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 378.0
HKD1_k127_7628902_1 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 328.0
HKD1_k127_7644808_0 FtsX-like permease family K02004 - - 4.821e-212 694.0
HKD1_k127_7644808_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 369.0
HKD1_k127_7644808_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 349.0
HKD1_k127_7644808_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 312.0
HKD1_k127_7644808_4 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000004451 181.0
HKD1_k127_7644808_5 CoA binding domain - - - 0.000000000000000000000000000000000000000000001369 171.0
HKD1_k127_7649532_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 602.0
HKD1_k127_7649532_1 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 429.0
HKD1_k127_7649532_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000003749 86.0
HKD1_k127_7649532_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000001071 73.0
HKD1_k127_7656601_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 591.0
HKD1_k127_7656601_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.00000000000000000001468 105.0
HKD1_k127_7659996_0 - - - - 1.968e-254 801.0
HKD1_k127_7659996_1 CDP-alcohol phosphatidyltransferase. Source PGD - - - 0.000000000000006414 85.0
HKD1_k127_7667690_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 494.0
HKD1_k127_7667690_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 325.0
HKD1_k127_7667690_2 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 295.0
HKD1_k127_7685983_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 511.0
HKD1_k127_7693444_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 415.0
HKD1_k127_7693444_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
HKD1_k127_7693444_2 amino acid ABC transporter, ATP-binding protein K01995 - - 0.0000000000000000000000000000000000000000000168 179.0
HKD1_k127_7695554_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 464.0
HKD1_k127_7695554_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 449.0
HKD1_k127_7695554_2 TIGRFAM cytochrome C family protein - - - 0.000006541 53.0
HKD1_k127_7697175_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 467.0
HKD1_k127_7697175_1 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002817 277.0
HKD1_k127_7701955_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 530.0
HKD1_k127_7701955_1 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 395.0
HKD1_k127_7701955_2 dehydratase - - - 0.000000000000000000000000000000000000000000000000000006748 210.0
HKD1_k127_7701955_3 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000004643 99.0
HKD1_k127_7702241_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 319.0
HKD1_k127_7702241_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000001083 204.0
HKD1_k127_7702241_2 ABC transporter C-terminal domain K06158 - - 0.000007168 48.0
HKD1_k127_7711390_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 383.0
HKD1_k127_7711390_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000968 274.0
HKD1_k127_7711390_2 Transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000004449 196.0
HKD1_k127_7711390_3 - - - - 0.0000003824 52.0
HKD1_k127_7729263_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 8.629e-297 939.0
HKD1_k127_7729263_1 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000001191 192.0
HKD1_k127_7729263_2 peroxiredoxin, OsmC subfamily K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.0000000000000000000000000001473 127.0
HKD1_k127_7733370_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.696e-312 970.0
HKD1_k127_7733370_1 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 1.162e-232 731.0
HKD1_k127_7733370_2 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000003474 179.0
HKD1_k127_7733370_3 response regulator K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000001105 170.0
HKD1_k127_7733370_5 Histidine phosphatase superfamily (branch 1) K08296 - - 0.000000313 56.0
HKD1_k127_7734749_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 386.0
HKD1_k127_7734749_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 330.0
HKD1_k127_7734749_2 - - - - 0.0000000000000000000000000000019 127.0
HKD1_k127_7734749_3 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000004239 52.0
HKD1_k127_7740677_0 acyl-coa dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 567.0
HKD1_k127_7740677_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 482.0
HKD1_k127_7740677_2 acyl-coa dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 437.0
HKD1_k127_7740677_3 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 316.0
HKD1_k127_7740677_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 271.0
HKD1_k127_7740677_5 Putative thioesterase (yiiD_Cterm) - - - 0.0000000000000000000000000000000000000000000003163 172.0
HKD1_k127_7740677_6 Protein conserved in bacteria - - - 0.0000000000003183 79.0
HKD1_k127_7750549_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 348.0
HKD1_k127_7750549_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 331.0
HKD1_k127_7750549_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000001381 73.0
HKD1_k127_775910_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 383.0
HKD1_k127_775910_1 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000006006 261.0
HKD1_k127_785206_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1044.0
HKD1_k127_785206_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 550.0
HKD1_k127_785206_2 cold-shock protein K03704 - - 0.00000000000000000000000000000000005334 135.0
HKD1_k127_7904720_0 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 505.0
HKD1_k127_7904720_1 Thioesterase-like superfamily K07107 - - 0.000004739 52.0
HKD1_k127_7914162_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 529.0
HKD1_k127_7944878_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 537.0
HKD1_k127_7944878_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 396.0
HKD1_k127_7944878_2 AIR carboxylase K06898 - - 0.0000000000000000000000000000001181 123.0
HKD1_k127_79676_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 323.0
HKD1_k127_79676_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000009457 166.0
HKD1_k127_7984618_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 454.0
HKD1_k127_7984618_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009956 284.0
HKD1_k127_7984618_2 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 282.0
HKD1_k127_7984618_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001014 265.0
HKD1_k127_7984618_4 - - - - 0.000000000000000001364 93.0
HKD1_k127_7986835_0 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 316.0
HKD1_k127_7986835_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 303.0
HKD1_k127_7986835_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002834 278.0
HKD1_k127_7986835_3 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000006834 180.0
HKD1_k127_7986835_4 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000003391 160.0
HKD1_k127_7989232_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 2.298e-207 658.0
HKD1_k127_7989232_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 306.0
HKD1_k127_7989232_2 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000006489 191.0
HKD1_k127_7989232_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000009139 119.0
HKD1_k127_7989544_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 381.0
HKD1_k127_7989544_1 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 284.0
HKD1_k127_7989544_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
HKD1_k127_7989544_3 metal cluster binding K06940 - - 0.0000000000000000000000009719 120.0
HKD1_k127_8003877_0 GTP-binding protein K06207 - - 0.0 1107.0
HKD1_k127_8003877_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 323.0
HKD1_k127_8003877_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000004065 150.0
HKD1_k127_8003877_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000001348 153.0
HKD1_k127_8003877_4 Phenazine biosynthesis - - - 0.00000000000000001024 83.0
HKD1_k127_8003877_5 Galactose oxidase, central domain - - - 0.0000001173 63.0
HKD1_k127_8015331_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 9.941e-257 797.0
HKD1_k127_808445_0 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 403.0
HKD1_k127_808445_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 300.0
HKD1_k127_808445_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008887 265.0
HKD1_k127_827108_0 Arylsulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 377.0
HKD1_k127_827108_1 PAS fold - - - 0.00000000000000000000000000000000000000000000000004059 192.0
HKD1_k127_831188_0 ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 306.0
HKD1_k127_831188_1 protein heterodimerization activity - - - 0.00000000000002053 74.0
HKD1_k127_831188_2 Domain of Unknown Function (DUF1259) - - - 0.00000000002845 73.0
HKD1_k127_835177_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 5.461e-222 700.0
HKD1_k127_835177_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 295.0
HKD1_k127_835177_2 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.00000000000000000000000000000000000000000000000001056 182.0
HKD1_k127_867108_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001121 297.0
HKD1_k127_867108_1 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004134 268.0
HKD1_k127_867108_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000227 256.0
HKD1_k127_867108_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000006419 95.0
HKD1_k127_867108_4 AI-2E family transporter - - - 0.00000000004645 68.0
HKD1_k127_878988_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 449.0
HKD1_k127_878988_1 Nuclease-related domain - - - 0.0000000000000000000000000000000000001246 160.0
HKD1_k127_878988_2 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000008009 113.0
HKD1_k127_878988_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000007824 88.0
HKD1_k127_878988_4 - - - - 0.0000000496 64.0
HKD1_k127_878988_5 Beta-lactamase - - - 0.00006222 50.0
HKD1_k127_891059_0 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 507.0
HKD1_k127_891059_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 439.0
HKD1_k127_891059_2 transcriptional regulator K03892 - - 0.0000000000000001529 83.0
HKD1_k127_891059_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.000007822 48.0
HKD1_k127_899276_0 Sterol carrier protein - - - 0.00000000000000000000000000000000000000002009 161.0
HKD1_k127_899276_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000005622 147.0
HKD1_k127_920441_0 CBS domain containing protein K07182 - - 9.986e-199 630.0
HKD1_k127_920441_1 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 418.0
HKD1_k127_920441_2 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 400.0
HKD1_k127_920441_3 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 354.0
HKD1_k127_920441_4 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000004549 265.0
HKD1_k127_920441_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000004608 111.0
HKD1_k127_92718_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 545.0
HKD1_k127_92718_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 465.0
HKD1_k127_92718_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000004466 180.0
HKD1_k127_92718_3 LppP/LprE lipoprotein - - - 0.0000000000000000000000000000007793 142.0
HKD1_k127_92718_4 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 0.00000000000000002484 92.0
HKD1_k127_92718_5 Domain of unknown function (DUF4395) - - - 0.0000002566 64.0
HKD1_k127_936233_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 306.0
HKD1_k127_936233_1 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009596 243.0
HKD1_k127_949202_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.015e-288 896.0
HKD1_k127_949202_1 FAD dependent oxidoreductase K07137 - - 2.52e-222 706.0
HKD1_k127_949202_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 481.0
HKD1_k127_949202_3 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 412.0
HKD1_k127_949202_4 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 360.0
HKD1_k127_949202_5 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000006123 239.0
HKD1_k127_949202_6 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000001871 199.0
HKD1_k127_949202_7 peptidoglycan binding K02453,K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.0000000000000000000000000000000000623 144.0
HKD1_k127_956025_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 342.0
HKD1_k127_956025_1 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 325.0
HKD1_k127_956025_2 - - - - 0.0000000007718 63.0
HKD1_k127_96134_0 Putative amidoligase enzyme (DUF2126) - - - 4.624e-249 785.0
HKD1_k127_992594_0 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 478.0
HKD1_k127_992594_1 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 314.0
HKD1_k127_992594_2 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000002657 244.0
HKD1_k127_992594_3 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000001281 182.0