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Overview

ID MAG01749
Name HKD1_bin.69
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Rariloculales
Family Rariloculaceae
Genus FEN-1219
Species
Assembly information
Completeness (%) 79.84
Contamination (%) 0.54
GC content (%) 69.0
N50 (bp) 19,689
Genome size (bp) 3,300,452

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2935

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1018032_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 5.321e-220 707.0
HKD1_k127_1018032_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 3.466e-218 719.0
HKD1_k127_1018032_10 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 323.0
HKD1_k127_1018032_11 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 312.0
HKD1_k127_1018032_12 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 329.0
HKD1_k127_1018032_13 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 314.0
HKD1_k127_1018032_14 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 274.0
HKD1_k127_1018032_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002122 257.0
HKD1_k127_1018032_16 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000004425 247.0
HKD1_k127_1018032_17 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000003876 222.0
HKD1_k127_1018032_18 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000001977 226.0
HKD1_k127_1018032_19 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000001318 206.0
HKD1_k127_1018032_2 Enoyl-CoA hydratase/isomerase - - - 1.488e-196 633.0
HKD1_k127_1018032_20 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000002152 203.0
HKD1_k127_1018032_21 TIGRFAM periplasmic protein K02199 - - 0.00000000000000000000000000000000000000000000000005848 185.0
HKD1_k127_1018032_22 Pilus assembly protein PilZ K02676 - - 0.00000000000000000000000000000000000000000000000302 177.0
HKD1_k127_1018032_23 COG0501 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000000000000000000000000001864 180.0
HKD1_k127_1018032_24 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000001823 171.0
HKD1_k127_1018032_25 General secretion pathway protein K02456 - - 0.0000000000000000000000000000000000000000000002118 174.0
HKD1_k127_1018032_26 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07664 - - 0.000000000000000000000000000000000000000000005792 172.0
HKD1_k127_1018032_27 Redoxin domain protein - - - 0.000000000000000000000000000000000000001655 153.0
HKD1_k127_1018032_28 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000001532 153.0
HKD1_k127_1018032_29 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000001961 152.0
HKD1_k127_1018032_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 584.0
HKD1_k127_1018032_30 Cytochrome C biogenesis K02200 - - 0.0000000000000000000000000000000001083 149.0
HKD1_k127_1018032_31 Type II secretion system (T2SS), protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000000001448 136.0
HKD1_k127_1018032_32 subunit of a heme lyase K02200,K04017 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.00000000000000000000000000000714 131.0
HKD1_k127_1018032_33 Transcriptional regulator K21747 - - 0.00000000000000000000000000001861 129.0
HKD1_k127_1018032_34 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000004626 125.0
HKD1_k127_1018032_35 Rhomboid family - - - 0.0000000000000000000000000001075 123.0
HKD1_k127_1018032_36 Spore Coat Protein U domain - - - 0.0000000000000000000000002136 111.0
HKD1_k127_1018032_37 Type II transport protein GspH K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000005104 102.0
HKD1_k127_1018032_38 Domain of unknown function (DUF4266) - - - 0.000000000000000000207 98.0
HKD1_k127_1018032_39 pilus organization K07346 - - 0.00000000000002091 82.0
HKD1_k127_1018032_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 384.0
HKD1_k127_1018032_40 Spore Coat Protein U domain - - - 0.00000000000005273 79.0
HKD1_k127_1018032_41 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000007706 76.0
HKD1_k127_1018032_42 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000007325 71.0
HKD1_k127_1018032_43 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.00000001632 67.0
HKD1_k127_1018032_44 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.00000003138 66.0
HKD1_k127_1018032_45 COG2165 Type II secretory pathway, pseudopilin PulG K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000001472 59.0
HKD1_k127_1018032_46 Type II secretion system, protein N K02463 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000008099 59.0
HKD1_k127_1018032_47 AAA domain - - - 0.000001119 61.0
HKD1_k127_1018032_48 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.00000479 55.0
HKD1_k127_1018032_5 outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 387.0
HKD1_k127_1018032_6 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 355.0
HKD1_k127_1018032_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 354.0
HKD1_k127_1018032_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 342.0
HKD1_k127_1018032_9 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 334.0
HKD1_k127_11108_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 2.632e-301 940.0
HKD1_k127_11108_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 545.0
HKD1_k127_11108_10 FimV C-terminal K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000001363 262.0
HKD1_k127_11108_11 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000001179 251.0
HKD1_k127_11108_12 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000002728 152.0
HKD1_k127_11108_13 SnoaL-like domain - - - 0.0000000000000000000000000001344 125.0
HKD1_k127_11108_14 - - - - 0.00000000000000000001465 96.0
HKD1_k127_11108_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 393.0
HKD1_k127_11108_3 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 352.0
HKD1_k127_11108_4 lysine 2,3-aminomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 347.0
HKD1_k127_11108_5 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 303.0
HKD1_k127_11108_6 PFAM EAL domain K21025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 310.0
HKD1_k127_11108_7 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007859 284.0
HKD1_k127_11108_8 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000001106 265.0
HKD1_k127_11108_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000002478 253.0
HKD1_k127_1159368_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 585.0
HKD1_k127_1159368_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 601.0
HKD1_k127_1159368_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 565.0
HKD1_k127_1159368_3 With GlrK is part of a two-component signal transduction system regulating glmY K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 524.0
HKD1_k127_1159368_4 epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 465.0
HKD1_k127_1159368_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 442.0
HKD1_k127_1159368_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 355.0
HKD1_k127_1159368_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 313.0
HKD1_k127_1159368_8 HDOD domain - - - 0.0000000000000000000000000000000000000000001924 169.0
HKD1_k127_1222303_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 3.989e-302 932.0
HKD1_k127_1222303_1 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 593.0
HKD1_k127_1222303_2 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HKD1_k127_1222303_3 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 358.0
HKD1_k127_1222303_4 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000001778 252.0
HKD1_k127_1222303_5 Cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000003776 198.0
HKD1_k127_1222303_6 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000000000000000000000000000003093 126.0
HKD1_k127_1222303_7 COG0457 FOG TPR repeat - - - 0.0000000000000000007519 100.0
HKD1_k127_1227508_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.631e-205 652.0
HKD1_k127_1227508_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 438.0
HKD1_k127_1227508_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 411.0
HKD1_k127_1227508_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 402.0
HKD1_k127_1227508_4 Alkyl hydroperoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002078 230.0
HKD1_k127_1227508_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000004935 181.0
HKD1_k127_1235198_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 358.0
HKD1_k127_1235198_1 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004583 296.0
HKD1_k127_1235198_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008396 239.0
HKD1_k127_1331770_0 Efflux pump membrane transporter K18299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 529.0
HKD1_k127_1331770_1 PQQ enzyme repeat K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 503.0
HKD1_k127_1331770_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 386.0
HKD1_k127_1331770_3 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000001749 171.0
HKD1_k127_1331770_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000009376 176.0
HKD1_k127_1396507_0 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 385.0
HKD1_k127_1396507_1 methyltransferase activity - - - 0.00000000000000000000000000006093 123.0
HKD1_k127_1396507_2 RNA recognition motif - - - 0.0000000000000000000000001322 108.0
HKD1_k127_1396507_3 protein kinase activity - - - 0.0000000000000000000002018 108.0
HKD1_k127_1396507_4 Pfam:RRM_6 - - - 0.00003278 52.0
HKD1_k127_1408241_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001231 286.0
HKD1_k127_1408241_1 PFAM LppC K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000511 253.0
HKD1_k127_1408241_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.0000000000000000000000000000000000000000001902 161.0
HKD1_k127_1408241_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000003618 98.0
HKD1_k127_141008_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.265e-244 775.0
HKD1_k127_141008_1 Belongs to the peptidase S16 family - - - 6.197e-234 751.0
HKD1_k127_141008_10 PFAM isochorismatase hydrolase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000001265 258.0
HKD1_k127_141008_11 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000002219 224.0
HKD1_k127_141008_12 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000006693 214.0
HKD1_k127_141008_13 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000003004 189.0
HKD1_k127_141008_14 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000001638 148.0
HKD1_k127_141008_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001186 104.0
HKD1_k127_141008_16 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000006323 81.0
HKD1_k127_141008_17 Universal stress protein family K14055 - - 0.00000000000000008534 91.0
HKD1_k127_141008_19 - - - - 0.0000000004524 64.0
HKD1_k127_141008_2 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 1.406e-229 725.0
HKD1_k127_141008_20 Belongs to the universal stress protein A family - - - 0.000000008897 66.0
HKD1_k127_141008_3 Belongs to the RtcB family K14415 - 6.5.1.3 3.084e-216 679.0
HKD1_k127_141008_4 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 593.0
HKD1_k127_141008_5 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 502.0
HKD1_k127_141008_6 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 441.0
HKD1_k127_141008_7 nitrogen fixation sensor protein fixL K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 294.0
HKD1_k127_141008_8 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008046 270.0
HKD1_k127_141008_9 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005845 257.0
HKD1_k127_1412017_0 PFAM Amidohydrolase 3 - - - 8.496e-203 647.0
HKD1_k127_1412017_2 PIN domain - - - 0.000001017 58.0
HKD1_k127_1412017_3 TIGRFAM transcriptional regulator, AbrB family - - - 0.000002417 53.0
HKD1_k127_1469366_0 secondary active sulfate transmembrane transporter activity K03321 - - 1.06e-265 857.0
HKD1_k127_1469366_1 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 642.0
HKD1_k127_1469366_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 457.0
HKD1_k127_1469366_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003021 268.0
HKD1_k127_1469366_4 Radical SAM - - - 0.000000000005079 68.0
HKD1_k127_1469366_5 OmpA-like transmembrane domain K03286 - - 0.000000006671 66.0
HKD1_k127_1513872_0 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 443.0
HKD1_k127_1513872_1 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 376.0
HKD1_k127_1513872_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000006014 209.0
HKD1_k127_1513872_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000001202 59.0
HKD1_k127_1522998_0 phosphoenolpyruvate carboxylase activity K01595 - 4.1.1.31 7.359e-232 744.0
HKD1_k127_1522998_1 Cystathionine beta-synthase K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000882 267.0
HKD1_k127_1522998_2 Planctomycete cytochrome C - - - 0.0000000005415 61.0
HKD1_k127_1554666_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 4.13e-301 949.0
HKD1_k127_1554666_1 Glucose / Sorbosone dehydrogenase - - - 1.268e-211 669.0
HKD1_k127_1554666_2 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 437.0
HKD1_k127_1554666_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000001228 162.0
HKD1_k127_1554666_4 pfam nudix K08310 - 3.6.1.67 0.000000000000000000000000000005443 135.0
HKD1_k127_1562187_0 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 6.497e-198 628.0
HKD1_k127_1562187_1 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 611.0
HKD1_k127_1562187_10 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002041 265.0
HKD1_k127_1562187_11 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
HKD1_k127_1562187_12 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000001161 261.0
HKD1_k127_1562187_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000009689 233.0
HKD1_k127_1562187_14 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000006451 250.0
HKD1_k127_1562187_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000001435 227.0
HKD1_k127_1562187_16 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000003241 220.0
HKD1_k127_1562187_17 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.0000000000000000000000000000000000000000000000000000000002529 212.0
HKD1_k127_1562187_18 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000001406 207.0
HKD1_k127_1562187_19 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001348 199.0
HKD1_k127_1562187_2 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 555.0
HKD1_k127_1562187_20 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000006423 199.0
HKD1_k127_1562187_21 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000138 168.0
HKD1_k127_1562187_22 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000001293 147.0
HKD1_k127_1562187_23 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000001734 134.0
HKD1_k127_1562187_24 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000005777 118.0
HKD1_k127_1562187_25 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000007257 134.0
HKD1_k127_1562187_26 - K07283 - - 0.000000000000000000000000006754 121.0
HKD1_k127_1562187_27 Belongs to the UPF0149 family K09895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000001955 99.0
HKD1_k127_1562187_28 Trm112p-like protein - - - 0.0000000000000000001551 91.0
HKD1_k127_1562187_29 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000002515 101.0
HKD1_k127_1562187_3 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 465.0
HKD1_k127_1562187_30 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000001824 64.0
HKD1_k127_1562187_4 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 404.0
HKD1_k127_1562187_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 390.0
HKD1_k127_1562187_6 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 398.0
HKD1_k127_1562187_7 Type II secretory pathway component ExeA K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 321.0
HKD1_k127_1562187_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001283 277.0
HKD1_k127_1562187_9 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003991 264.0
HKD1_k127_1590185_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.061e-205 672.0
HKD1_k127_1590185_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.333e-199 632.0
HKD1_k127_1590185_10 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 308.0
HKD1_k127_1590185_11 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001667 261.0
HKD1_k127_1590185_12 cell wall glycoprotein biosynthetic process K00344,K01809,K01840,K03431,K04035,K15778,K16881 GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,1.6.5.5,2.7.7.13,5.3.1.8,5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002396 266.0
HKD1_k127_1590185_13 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000001008 258.0
HKD1_k127_1590185_14 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000001174 237.0
HKD1_k127_1590185_15 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000008366 234.0
HKD1_k127_1590185_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000911 228.0
HKD1_k127_1590185_17 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000002498 207.0
HKD1_k127_1590185_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000721 203.0
HKD1_k127_1590185_19 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000137 200.0
HKD1_k127_1590185_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 567.0
HKD1_k127_1590185_20 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000007194 192.0
HKD1_k127_1590185_21 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000000005106 132.0
HKD1_k127_1590185_22 membrane protein (DUF2306) - - - 0.000000000000000000000000000001566 128.0
HKD1_k127_1590185_23 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000005133 107.0
HKD1_k127_1590185_24 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000678 98.0
HKD1_k127_1590185_25 - - - - 0.0000000000000007407 92.0
HKD1_k127_1590185_26 Putative restriction endonuclease - - - 0.000000000000007758 76.0
HKD1_k127_1590185_28 Belongs to the UPF0250 family K09158 - - 0.000000000001464 77.0
HKD1_k127_1590185_29 enzyme of the cupin superfamily - - - 0.000000000005332 73.0
HKD1_k127_1590185_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 565.0
HKD1_k127_1590185_30 - - - - 0.00000000004906 69.0
HKD1_k127_1590185_31 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000003353 60.0
HKD1_k127_1590185_4 PCRF K02835 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 481.0
HKD1_k127_1590185_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 429.0
HKD1_k127_1590185_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 415.0
HKD1_k127_1590185_7 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 409.0
HKD1_k127_1590185_8 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 358.0
HKD1_k127_1590185_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 319.0
HKD1_k127_1592413_0 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 441.0
HKD1_k127_1592413_1 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 339.0
HKD1_k127_1592413_2 flagellar assembly protein FliH K02411 - - 0.000000000000000000001352 102.0
HKD1_k127_1592413_3 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000182 91.0
HKD1_k127_1592413_4 response regulator K10943 - - 0.0000002164 56.0
HKD1_k127_1603871_0 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 525.0
HKD1_k127_1603871_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 375.0
HKD1_k127_1603871_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000001078 226.0
HKD1_k127_1603871_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000001901 208.0
HKD1_k127_1603871_4 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000009062 120.0
HKD1_k127_1603871_5 HIT domain - - - 0.00000000000000004189 87.0
HKD1_k127_1603871_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000003197 72.0
HKD1_k127_1651069_0 DEAD DEAH box K03724 - - 3.289e-318 1004.0
HKD1_k127_1651069_1 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 2.068e-201 661.0
HKD1_k127_1651069_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000001034 216.0
HKD1_k127_1651069_3 Sulfotransferase domain K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000009348 212.0
HKD1_k127_1651069_4 Sulfotransferase domain K01014 - 2.8.2.1 0.0000000000000000000000000000000005189 136.0
HKD1_k127_1696846_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 455.0
HKD1_k127_1696846_1 SurA N-terminal domain K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 362.0
HKD1_k127_1696846_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 340.0
HKD1_k127_1696846_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
HKD1_k127_1696846_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000001994 263.0
HKD1_k127_1696846_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000006456 201.0
HKD1_k127_1806199_0 ABC transporter K06147,K06148 - - 3.3e-246 777.0
HKD1_k127_1806199_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 7.514e-246 792.0
HKD1_k127_1806199_10 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 324.0
HKD1_k127_1806199_11 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 305.0
HKD1_k127_1806199_12 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 317.0
HKD1_k127_1806199_13 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 287.0
HKD1_k127_1806199_14 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002067 301.0
HKD1_k127_1806199_15 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002556 263.0
HKD1_k127_1806199_16 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000005638 256.0
HKD1_k127_1806199_17 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000002828 248.0
HKD1_k127_1806199_18 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000705 241.0
HKD1_k127_1806199_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004669 237.0
HKD1_k127_1806199_2 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 1.414e-205 660.0
HKD1_k127_1806199_20 GDSL-like Lipase/Acylhydrolase family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000001591 214.0
HKD1_k127_1806199_21 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000306 203.0
HKD1_k127_1806199_22 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000545 200.0
HKD1_k127_1806199_23 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000001044 179.0
HKD1_k127_1806199_24 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000008552 183.0
HKD1_k127_1806199_25 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase - - - 0.0000000000000000000000000000000000006681 148.0
HKD1_k127_1806199_26 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000008741 158.0
HKD1_k127_1806199_27 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000001662 145.0
HKD1_k127_1806199_28 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000006288 133.0
HKD1_k127_1806199_29 Large extracellular alpha-helical protein - - - 0.0000000000000000000000001301 113.0
HKD1_k127_1806199_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 589.0
HKD1_k127_1806199_30 - - - - 0.0000000000000000007607 100.0
HKD1_k127_1806199_31 Putative prokaryotic signal transducing protein - - - 0.0000000000000002991 83.0
HKD1_k127_1806199_32 Sterol-binding domain protein K03690 - - 0.0000000000000021 89.0
HKD1_k127_1806199_34 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000005419 80.0
HKD1_k127_1806199_35 Phospholipid methyltransferase - - - 0.0001761 52.0
HKD1_k127_1806199_4 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 524.0
HKD1_k127_1806199_5 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 462.0
HKD1_k127_1806199_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 442.0
HKD1_k127_1806199_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 401.0
HKD1_k127_1806199_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 407.0
HKD1_k127_1806199_9 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 359.0
HKD1_k127_185271_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788 - - 0.0 1372.0
HKD1_k127_185271_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1353.0
HKD1_k127_185271_10 PepSY-associated TM region - - - 0.0000000000000000000000000002518 126.0
HKD1_k127_185271_11 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000001058 92.0
HKD1_k127_185271_12 COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit - - - 0.000000000000001012 79.0
HKD1_k127_185271_13 Metallo-beta-lactamase superfamily - - - 0.0004787 53.0
HKD1_k127_185271_2 Nitric oxide reductase - - - 2.804e-319 1014.0
HKD1_k127_185271_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 500.0
HKD1_k127_185271_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 439.0
HKD1_k127_185271_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 395.0
HKD1_k127_185271_6 Asp Glu hydantoin racemase K01799,K06033 - 4.1.1.76,5.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000005493 239.0
HKD1_k127_185271_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002805 218.0
HKD1_k127_185271_8 - - - - 0.000000000000000000000000000000000000000000001432 190.0
HKD1_k127_185271_9 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.0000000000000000000000000000000001096 147.0
HKD1_k127_1915062_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 6.944e-300 929.0
HKD1_k127_1915062_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 7.729e-226 717.0
HKD1_k127_1915062_10 Double sensory domain of two-component sensor kinase - - - 0.0000000000000000000000000000000000000000000000000000000000004185 226.0
HKD1_k127_1915062_11 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000008179 224.0
HKD1_k127_1915062_12 - - - - 0.000000000000000000000000000000000000000000000000000000004509 209.0
HKD1_k127_1915062_13 HDOD domain - - - 0.000000000000000000000000000000000000000000000000004353 194.0
HKD1_k127_1915062_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000002367 175.0
HKD1_k127_1915062_15 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000448 148.0
HKD1_k127_1915062_16 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000003603 140.0
HKD1_k127_1915062_17 Transcriptional regulator K07727 - - 0.00000000000000000000000001805 111.0
HKD1_k127_1915062_18 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000001207 94.0
HKD1_k127_1915062_19 Protein of unknown function (DUF2975) - - - 0.0000000000000001236 87.0
HKD1_k127_1915062_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 592.0
HKD1_k127_1915062_20 Polypeptide-transport-associated domain protein ShlB-type - - - 0.00000000005028 72.0
HKD1_k127_1915062_21 diguanylate cyclase - - - 0.0000003449 61.0
HKD1_k127_1915062_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 562.0
HKD1_k127_1915062_4 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 429.0
HKD1_k127_1915062_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 415.0
HKD1_k127_1915062_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 407.0
HKD1_k127_1915062_7 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 391.0
HKD1_k127_1915062_8 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 363.0
HKD1_k127_1915062_9 TIGRFAM Diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000242 239.0
HKD1_k127_1928670_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1088.0
HKD1_k127_1928670_1 transporter - - - 3.994e-261 835.0
HKD1_k127_1928670_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002211 258.0
HKD1_k127_1928670_11 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000001405 230.0
HKD1_k127_1928670_12 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000002195 204.0
HKD1_k127_1928670_13 PFAM cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000108 206.0
HKD1_k127_1928670_14 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000009094 189.0
HKD1_k127_1928670_15 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000008315 190.0
HKD1_k127_1928670_16 phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000007444 182.0
HKD1_k127_1928670_17 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.00000000000000000000000000000000000000000003523 171.0
HKD1_k127_1928670_18 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000001683 165.0
HKD1_k127_1928670_19 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000004906 101.0
HKD1_k127_1928670_2 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 525.0
HKD1_k127_1928670_20 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.0000000000000000003478 89.0
HKD1_k127_1928670_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000003184 72.0
HKD1_k127_1928670_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.00000001887 58.0
HKD1_k127_1928670_3 Cys/Met metabolism PLP-dependent enzyme K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 479.0
HKD1_k127_1928670_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 390.0
HKD1_k127_1928670_5 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 327.0
HKD1_k127_1928670_6 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 321.0
HKD1_k127_1928670_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 293.0
HKD1_k127_1928670_8 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008411 295.0
HKD1_k127_1928670_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 265.0
HKD1_k127_1929552_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.82e-297 922.0
HKD1_k127_1929552_1 Radical SAM - - - 6.722e-196 634.0
HKD1_k127_1929552_10 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 331.0
HKD1_k127_1929552_11 lipoprotein biosynthetic process K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004429 243.0
HKD1_k127_1929552_13 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000000000005875 201.0
HKD1_k127_1929552_14 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000006805 207.0
HKD1_k127_1929552_15 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000002218 189.0
HKD1_k127_1929552_16 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000001125 162.0
HKD1_k127_1929552_17 Carboxylesterase family - - - 0.000000000000000000000000000000000000004367 161.0
HKD1_k127_1929552_18 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000002688 151.0
HKD1_k127_1929552_19 Flagellar motor protein K02557 - - 0.0000000000000000000000000007478 124.0
HKD1_k127_1929552_2 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 582.0
HKD1_k127_1929552_20 MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000003856 122.0
HKD1_k127_1929552_21 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000005179 123.0
HKD1_k127_1929552_23 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000007569 57.0
HKD1_k127_1929552_24 Methyltransferase FkbM domain - - - 0.00003674 54.0
HKD1_k127_1929552_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00007828 46.0
HKD1_k127_1929552_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 537.0
HKD1_k127_1929552_5 SMART transcription factor jumonji jmjC K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 402.0
HKD1_k127_1929552_6 Hexosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 390.0
HKD1_k127_1929552_7 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 389.0
HKD1_k127_1929552_8 glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 366.0
HKD1_k127_1929552_9 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 338.0
HKD1_k127_1934313_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 2.223e-315 985.0
HKD1_k127_1934313_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 4.031e-231 747.0
HKD1_k127_1934313_10 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000001014 141.0
HKD1_k127_1934313_11 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000001323 129.0
HKD1_k127_1934313_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000393 87.0
HKD1_k127_1934313_2 TonB dependent receptor - - - 1.101e-203 675.0
HKD1_k127_1934313_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 408.0
HKD1_k127_1934313_4 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 301.0
HKD1_k127_1934313_5 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003976 242.0
HKD1_k127_1934313_6 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
HKD1_k127_1934313_7 universal stress protein K14055 - - 0.0000000000000000000000000000000000000000000000001392 189.0
HKD1_k127_1934313_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000005461 162.0
HKD1_k127_1934313_9 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000223 160.0
HKD1_k127_19715_0 Aminotransferase class-III K01845 - 5.4.3.8 2.305e-244 766.0
HKD1_k127_19715_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 469.0
HKD1_k127_19715_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 406.0
HKD1_k127_19715_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 289.0
HKD1_k127_19715_4 phosphate transport system permease K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 300.0
HKD1_k127_19715_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000002487 111.0
HKD1_k127_19715_6 Copper resistance protein D K07245 - - 0.000000000000001326 88.0
HKD1_k127_19715_8 CopC domain K07156 - - 0.000000005688 62.0
HKD1_k127_2047430_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.051e-229 718.0
HKD1_k127_2047430_1 PFAM glycoside hydrolase 15-related - - - 3.763e-216 689.0
HKD1_k127_2047430_10 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000006097 181.0
HKD1_k127_2047430_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000003495 138.0
HKD1_k127_2047430_12 epsilon subunit K02114 - - 0.00000000000000000000000000001189 128.0
HKD1_k127_2047430_13 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000000002205 119.0
HKD1_k127_2047430_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000003326 114.0
HKD1_k127_2047430_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.291e-213 676.0
HKD1_k127_2047430_3 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 441.0
HKD1_k127_2047430_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 366.0
HKD1_k127_2047430_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 292.0
HKD1_k127_2047430_6 Transcriptional regulator, LysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000001474 230.0
HKD1_k127_2047430_7 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000001756 192.0
HKD1_k127_2047430_8 atp synthase K02115 - - 0.000000000000000000000000000000000000000000000000005541 201.0
HKD1_k127_2047430_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000001204 186.0
HKD1_k127_2080239_0 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 379.0
HKD1_k127_2080239_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000007524 266.0
HKD1_k127_2080239_2 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000007012 114.0
HKD1_k127_2080239_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000001935 93.0
HKD1_k127_2080239_4 sequence-specific DNA binding - - - 0.00000000000000002013 92.0
HKD1_k127_2080239_5 Universal stress protein family - - - 0.00000000000003726 80.0
HKD1_k127_2129513_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.163e-231 721.0
HKD1_k127_2129513_1 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 317.0
HKD1_k127_2129513_2 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 300.0
HKD1_k127_2154365_0 Sugar (and other) transporter - - - 2.284e-221 694.0
HKD1_k127_2154365_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 377.0
HKD1_k127_2154365_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000007711 192.0
HKD1_k127_2154365_3 LysE type translocator - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000002669 165.0
HKD1_k127_2154365_4 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.000000000000000000000000002431 126.0
HKD1_k127_2154365_5 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000002798 113.0
HKD1_k127_2154365_6 protein conserved in bacteria K09914 - - 0.0000000000000000000000001121 119.0
HKD1_k127_2210486_0 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 9.499e-256 803.0
HKD1_k127_2210486_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.006e-215 693.0
HKD1_k127_2210486_10 NAD dependent epimerase/dehydratase family K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 448.0
HKD1_k127_2210486_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 448.0
HKD1_k127_2210486_12 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 435.0
HKD1_k127_2210486_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 360.0
HKD1_k127_2210486_14 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 358.0
HKD1_k127_2210486_15 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006026 284.0
HKD1_k127_2210486_16 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000281 288.0
HKD1_k127_2210486_17 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005626 275.0
HKD1_k127_2210486_18 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004135 254.0
HKD1_k127_2210486_19 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000436 257.0
HKD1_k127_2210486_2 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 2.905e-209 661.0
HKD1_k127_2210486_20 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000116 237.0
HKD1_k127_2210486_21 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000004039 226.0
HKD1_k127_2210486_22 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000004202 226.0
HKD1_k127_2210486_23 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000002952 184.0
HKD1_k127_2210486_24 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000347 179.0
HKD1_k127_2210486_25 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000004418 180.0
HKD1_k127_2210486_26 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000002721 164.0
HKD1_k127_2210486_27 Hydrolase - - - 0.0000000000000000000000000000000000000005363 158.0
HKD1_k127_2210486_28 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002482 138.0
HKD1_k127_2210486_29 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001775 118.0
HKD1_k127_2210486_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 555.0
HKD1_k127_2210486_30 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000008642 109.0
HKD1_k127_2210486_31 membrane - - - 0.00000002135 65.0
HKD1_k127_2210486_32 Site-specific recombinase, DNA invertase Pin - - - 0.0000355 51.0
HKD1_k127_2210486_33 - - - - 0.0005438 51.0
HKD1_k127_2210486_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 547.0
HKD1_k127_2210486_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 561.0
HKD1_k127_2210486_6 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 533.0
HKD1_k127_2210486_7 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 533.0
HKD1_k127_2210486_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 476.0
HKD1_k127_2210486_9 Asparagine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 463.0
HKD1_k127_2219836_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 1.702e-251 812.0
HKD1_k127_2219836_1 Aldehyde dehydrogenase family K00146 - 1.2.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 606.0
HKD1_k127_2219836_10 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 356.0
HKD1_k127_2219836_11 Preprotein translocase subunit TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 311.0
HKD1_k127_2219836_12 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 300.0
HKD1_k127_2219836_13 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000001036 201.0
HKD1_k127_2219836_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000004919 155.0
HKD1_k127_2219836_15 NERD domain protein - - - 0.00000000000000000004595 97.0
HKD1_k127_2219836_16 Transcriptional regulator K18301 - - 0.0000000000001737 79.0
HKD1_k127_2219836_17 Bacterial regulatory proteins, tetR family - - - 0.0000008941 59.0
HKD1_k127_2219836_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 621.0
HKD1_k127_2219836_3 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 495.0
HKD1_k127_2219836_4 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 428.0
HKD1_k127_2219836_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 413.0
HKD1_k127_2219836_6 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 409.0
HKD1_k127_2219836_7 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 410.0
HKD1_k127_2219836_8 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 393.0
HKD1_k127_2219836_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 346.0
HKD1_k127_2261625_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 470.0
HKD1_k127_2261625_1 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 359.0
HKD1_k127_2261625_2 enterobactin catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 301.0
HKD1_k127_2261625_3 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 306.0
HKD1_k127_2261625_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
HKD1_k127_2261625_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000003528 229.0
HKD1_k127_2261625_6 LysR substrate binding domain K05817 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000781 201.0
HKD1_k127_2261625_7 - - - - 0.00000000000000000000000000000000219 143.0
HKD1_k127_2261625_8 decarboxylase K01607 - 4.1.1.44 0.00000000000002412 86.0
HKD1_k127_2301253_0 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 321.0
HKD1_k127_2301253_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 305.0
HKD1_k127_2301253_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000001213 196.0
HKD1_k127_2301253_3 - - - - 0.0000000000000000000000000000000008828 148.0
HKD1_k127_2301253_4 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000001014 132.0
HKD1_k127_2301253_5 GtrA-like protein - - - 0.0000000000000000000005034 102.0
HKD1_k127_2301253_6 - - - - 0.00000000003006 75.0
HKD1_k127_2301253_7 Integrin alpha (beta-propellor repeats). - - - 0.00000000003845 66.0
HKD1_k127_2301253_8 - - - - 0.00007964 54.0
HKD1_k127_2340353_0 DNA topological change K03168 - 5.99.1.2 9.217e-199 650.0
HKD1_k127_2340353_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 389.0
HKD1_k127_2340353_2 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000000001845 234.0
HKD1_k127_2340353_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000002808 155.0
HKD1_k127_2340353_4 Aminotransferase, class I K10907 - - 0.0000000000000000000000004275 108.0
HKD1_k127_2340353_6 - - - - 0.000000000003756 71.0
HKD1_k127_2440041_0 Carbon starvation protein K06200 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0 1084.0
HKD1_k127_2440041_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 437.0
HKD1_k127_2440041_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 375.0
HKD1_k127_2440041_3 Selenoprotein, putative - - - 0.00000000000000007963 83.0
HKD1_k127_2440041_4 Lactonase, 7-bladed beta-propeller - - - 0.000001783 52.0
HKD1_k127_246064_0 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 557.0
HKD1_k127_246064_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 387.0
HKD1_k127_246064_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 355.0
HKD1_k127_2466440_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1294.0
HKD1_k127_2466440_1 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 346.0
HKD1_k127_2466440_2 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 336.0
HKD1_k127_2466440_3 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 295.0
HKD1_k127_2466440_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003127 267.0
HKD1_k127_2466440_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000004254 217.0
HKD1_k127_2466440_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000006361 199.0
HKD1_k127_2466440_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000003624 171.0
HKD1_k127_2466440_9 Protein of unknown function (DUF3240) - - - 0.000000000000000001937 89.0
HKD1_k127_2498516_0 Diguanylate cyclase - - - 1.016e-196 644.0
HKD1_k127_2498516_1 L-2-hydroxyglutarate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 412.0
HKD1_k127_2498516_10 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000331 220.0
HKD1_k127_2498516_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000134 231.0
HKD1_k127_2498516_12 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000002575 207.0
HKD1_k127_2498516_13 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000004923 206.0
HKD1_k127_2498516_14 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000003005 188.0
HKD1_k127_2498516_15 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000009971 165.0
HKD1_k127_2498516_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000371 161.0
HKD1_k127_2498516_17 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000000004473 155.0
HKD1_k127_2498516_18 - - - - 0.0000000000000000000000000000001005 128.0
HKD1_k127_2498516_2 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 362.0
HKD1_k127_2498516_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 358.0
HKD1_k127_2498516_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 355.0
HKD1_k127_2498516_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 317.0
HKD1_k127_2498516_6 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 304.0
HKD1_k127_2498516_7 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 293.0
HKD1_k127_2498516_8 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 283.0
HKD1_k127_2498516_9 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001671 273.0
HKD1_k127_255971_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1217.0
HKD1_k127_255971_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1159.0
HKD1_k127_255971_10 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 426.0
HKD1_k127_255971_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 383.0
HKD1_k127_255971_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 348.0
HKD1_k127_255971_13 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 350.0
HKD1_k127_255971_14 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 320.0
HKD1_k127_255971_15 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 316.0
HKD1_k127_255971_16 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 309.0
HKD1_k127_255971_17 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001257 297.0
HKD1_k127_255971_18 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000001736 271.0
HKD1_k127_255971_19 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 263.0
HKD1_k127_255971_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.636e-302 935.0
HKD1_k127_255971_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007081 258.0
HKD1_k127_255971_21 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000005829 254.0
HKD1_k127_255971_22 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000005429 244.0
HKD1_k127_255971_23 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000002292 215.0
HKD1_k127_255971_24 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000009956 212.0
HKD1_k127_255971_25 PFAM MucB RseB K03598 - - 0.00000000000000000000000000000000000000000000000000000005349 209.0
HKD1_k127_255971_26 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000002199 207.0
HKD1_k127_255971_27 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000738 194.0
HKD1_k127_255971_28 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000004406 191.0
HKD1_k127_255971_29 PFAM Acetyltransferase (GNAT) family K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000001597 189.0
HKD1_k127_255971_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.112e-281 875.0
HKD1_k127_255971_30 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000491 188.0
HKD1_k127_255971_31 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000003971 168.0
HKD1_k127_255971_32 phosphoribosyltransferase K00760 - 2.4.2.8 0.000000000000000000000000000000000000000005436 160.0
HKD1_k127_255971_33 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000008932 156.0
HKD1_k127_255971_34 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000002541 126.0
HKD1_k127_255971_35 succinate dehydrogenase K00241 - - 0.0000000000000000000000001448 111.0
HKD1_k127_255971_36 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0016740,GO:0016772,GO:0016780,GO:0044238,GO:0071704,GO:1901576 2.7.8.7 0.000000000000000000000001064 109.0
HKD1_k127_255971_37 succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.00000000000000000000005974 103.0
HKD1_k127_255971_38 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000272 98.0
HKD1_k127_255971_39 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000001955 86.0
HKD1_k127_255971_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.647e-266 831.0
HKD1_k127_255971_40 cell redox homeostasis K00384 - 1.8.1.9 0.0000000000002958 74.0
HKD1_k127_255971_41 Flavinator of succinate dehydrogenase K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - 0.000000000001458 71.0
HKD1_k127_255971_42 Peptidoglycan-binding protein, CsiV - - - 0.0000000001966 73.0
HKD1_k127_255971_43 Domain of unknown function (DUF4845) - - - 0.0000000007955 69.0
HKD1_k127_255971_44 Protein of unknown function (DUF1674) - - - 0.0000006639 59.0
HKD1_k127_255971_45 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E K03597 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000007673 59.0
HKD1_k127_255971_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.029e-199 634.0
HKD1_k127_255971_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 584.0
HKD1_k127_255971_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 505.0
HKD1_k127_255971_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 450.0
HKD1_k127_255971_9 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 426.0
HKD1_k127_2578383_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1202.0
HKD1_k127_2578383_1 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 8.539e-309 993.0
HKD1_k127_2578383_10 signal transduction histidine kinase K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 320.0
HKD1_k127_2578383_11 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 291.0
HKD1_k127_2578383_12 Nucleoside triphosphate K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 284.0
HKD1_k127_2578383_13 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001538 264.0
HKD1_k127_2578383_14 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000287 256.0
HKD1_k127_2578383_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000033 225.0
HKD1_k127_2578383_16 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000369 162.0
HKD1_k127_2578383_17 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000002634 162.0
HKD1_k127_2578383_18 protein acetylation - - - 0.000000000000000000000001189 109.0
HKD1_k127_2578383_19 outer membrane lipoprotein - - - 0.0000000000000000000006841 104.0
HKD1_k127_2578383_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.177e-210 683.0
HKD1_k127_2578383_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.127e-202 641.0
HKD1_k127_2578383_4 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 601.0
HKD1_k127_2578383_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 562.0
HKD1_k127_2578383_6 COG4257 Streptogramin lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 429.0
HKD1_k127_2578383_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 386.0
HKD1_k127_2578383_8 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 358.0
HKD1_k127_2578383_9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 321.0
HKD1_k127_2582181_0 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 2.112e-245 788.0
HKD1_k127_2582181_1 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000006478 175.0
HKD1_k127_2582181_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000004365 152.0
HKD1_k127_2582181_3 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000002459 62.0
HKD1_k127_2601058_0 Major Facilitator Superfamily - - - 7.242e-257 804.0
HKD1_k127_2601058_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 383.0
HKD1_k127_2601058_2 PFAM Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 379.0
HKD1_k127_2601058_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000004601 264.0
HKD1_k127_2601058_4 - - - - 0.000000000000000000000000000000000000000000000008291 189.0
HKD1_k127_2601058_5 Haem-degrading - - - 0.0000000000000000000000000000000000004161 148.0
HKD1_k127_2619216_0 Adenylate cyclase - - - 1.685e-232 737.0
HKD1_k127_2619216_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 571.0
HKD1_k127_2619216_10 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000008506 236.0
HKD1_k127_2619216_11 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000007603 194.0
HKD1_k127_2619216_12 Phosphatidylethanolamine-binding protein - - - 0.00000000000000000000000000000000000000000000441 173.0
HKD1_k127_2619216_13 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000004851 165.0
HKD1_k127_2619216_14 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000837 132.0
HKD1_k127_2619216_15 - - - - 0.00000000000000003362 84.0
HKD1_k127_2619216_16 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000002519 65.0
HKD1_k127_2619216_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 516.0
HKD1_k127_2619216_3 Competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 446.0
HKD1_k127_2619216_4 Lipoprotein releasing system transmembrane protein K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 397.0
HKD1_k127_2619216_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 347.0
HKD1_k127_2619216_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 311.0
HKD1_k127_2619216_7 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 295.0
HKD1_k127_2619216_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000001438 284.0
HKD1_k127_2619216_9 MotA TolQ ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002106 244.0
HKD1_k127_262905_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 410.0
HKD1_k127_262905_1 Oxidoreductase FAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 366.0
HKD1_k127_262905_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000006057 106.0
HKD1_k127_262905_2 PFAM Type II secretion system protein E K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 328.0
HKD1_k127_262905_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 338.0
HKD1_k127_262905_4 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000499 219.0
HKD1_k127_262905_5 response regulator receiver K02657 - - 0.000000000000000000000000000000000000000000000000000002299 218.0
HKD1_k127_262905_6 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000116 162.0
HKD1_k127_262905_7 chemotaxis protein K02660 - - 0.0000000000000000000000000000000003368 146.0
HKD1_k127_262905_8 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000003504 134.0
HKD1_k127_262905_9 Two component signalling adaptor domain K02659 - - 0.000000000000000000000000000001143 132.0
HKD1_k127_266182_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1196.0
HKD1_k127_266182_1 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 499.0
HKD1_k127_266182_10 histone acetyltransferase HPA2 and related acetyltransferases - GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.000000000000000000004513 104.0
HKD1_k127_266182_11 ADP binding - - - 0.0000000000649 67.0
HKD1_k127_266182_2 alcohol dehydrogenase K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 529.0
HKD1_k127_266182_3 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 445.0
HKD1_k127_266182_5 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 394.0
HKD1_k127_266182_6 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 297.0
HKD1_k127_266182_7 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003117 240.0
HKD1_k127_266182_8 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000001477 209.0
HKD1_k127_266182_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08738 - - 0.00000000000000000000000000000000000000000000000003569 185.0
HKD1_k127_269994_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 543.0
HKD1_k127_269994_1 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 426.0
HKD1_k127_269994_10 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000001181 187.0
HKD1_k127_269994_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000014 173.0
HKD1_k127_269994_12 AntiSigma factor - - - 0.000000000000000000000009138 115.0
HKD1_k127_269994_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 424.0
HKD1_k127_269994_3 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 332.0
HKD1_k127_269994_4 TIGRFAM anion transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 342.0
HKD1_k127_269994_5 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 309.0
HKD1_k127_269994_6 DNA polymerase type-B family K02336 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003226 286.0
HKD1_k127_269994_7 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000002478 254.0
HKD1_k127_269994_8 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000002207 228.0
HKD1_k127_269994_9 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000001608 217.0
HKD1_k127_2703242_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.0 1274.0
HKD1_k127_2703242_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1074.0
HKD1_k127_2703242_10 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.000000000000000000000000000000000000004176 154.0
HKD1_k127_2703242_11 Signal peptidase (SPase) II - - - 0.00000001092 58.0
HKD1_k127_2703242_12 alcohol dehydrogenase - - - 0.0005693 43.0
HKD1_k127_2703242_2 ABC transporter K02049,K15555,K15578 - - 1.328e-231 733.0
HKD1_k127_2703242_3 NMT1-like family K15576 - - 7.083e-222 698.0
HKD1_k127_2703242_4 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 516.0
HKD1_k127_2703242_5 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 443.0
HKD1_k127_2703242_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 392.0
HKD1_k127_2703242_7 Glutathione S-Transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 326.0
HKD1_k127_2703242_8 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576,K22067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 316.0
HKD1_k127_2703242_9 response regulator receiver K07183 - - 0.0000000000000000000000000000000000000000000000000000000000000000000058 243.0
HKD1_k127_2707086_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1687.0
HKD1_k127_2707086_1 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 3.931e-239 749.0
HKD1_k127_2707086_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007478 281.0
HKD1_k127_2707086_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000318 243.0
HKD1_k127_2757418_0 Major facilitator superfamily K08218 - - 3.916e-194 614.0
HKD1_k127_2757418_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 458.0
HKD1_k127_2757418_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000004528 239.0
HKD1_k127_2757418_11 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002485 231.0
HKD1_k127_2757418_12 Histidine kinase - - - 0.0000000000000000000000000000000000006491 158.0
HKD1_k127_2757418_13 Domain of unknown function (DUF4124) - - - 0.0000000000000000000001208 106.0
HKD1_k127_2757418_15 - - - - 0.00003418 56.0
HKD1_k127_2757418_2 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 328.0
HKD1_k127_2757418_3 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 319.0
HKD1_k127_2757418_4 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 304.0
HKD1_k127_2757418_5 PFAM AsmA family protein K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 309.0
HKD1_k127_2757418_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 292.0
HKD1_k127_2757418_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003992 276.0
HKD1_k127_2757418_8 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000001417 249.0
HKD1_k127_2757418_9 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001711 248.0
HKD1_k127_2769379_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 2.275e-225 710.0
HKD1_k127_2769379_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 346.0
HKD1_k127_2769379_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 291.0
HKD1_k127_2769379_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001035 276.0
HKD1_k127_2769379_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001758 246.0
HKD1_k127_2769379_5 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000006608 244.0
HKD1_k127_2769379_6 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002038 220.0
HKD1_k127_2769379_7 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000004218 199.0
HKD1_k127_2769379_8 Sh3 type 3 domain protein - - - 0.00000000000234 73.0
HKD1_k127_2769379_9 Glycine-zipper domain - - - 0.0000000000239 74.0
HKD1_k127_2780161_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 424.0
HKD1_k127_2780161_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 316.0
HKD1_k127_2780161_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000005868 157.0
HKD1_k127_2780161_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000001886 152.0
HKD1_k127_2780161_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000004225 133.0
HKD1_k127_2780161_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000008018 112.0
HKD1_k127_2780161_14 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000001984 113.0
HKD1_k127_2780161_15 translation elongation factor activity K02358 - - 0.0000000000000000304 81.0
HKD1_k127_2780161_16 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000001841 60.0
HKD1_k127_2780161_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
HKD1_k127_2780161_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 284.0
HKD1_k127_2780161_4 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008562 243.0
HKD1_k127_2780161_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000001908 228.0
HKD1_k127_2780161_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000006406 209.0
HKD1_k127_2780161_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000005898 179.0
HKD1_k127_2780161_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000001276 168.0
HKD1_k127_2780161_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000008965 158.0
HKD1_k127_2785124_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 387.0
HKD1_k127_2785124_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 243.0
HKD1_k127_2785124_2 Flavodoxin - - - 0.000000000000000000000000000000000000004547 151.0
HKD1_k127_2785124_3 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000005742 128.0
HKD1_k127_2785124_4 Immunoglobulin-like domain of bacterial spore germination - - - 0.000000000000000000000000000006507 128.0
HKD1_k127_2785124_5 long-chain fatty acid transport protein - - - 0.000000000000001188 90.0
HKD1_k127_2822604_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 579.0
HKD1_k127_2822604_1 serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000109 269.0
HKD1_k127_2822604_2 TraB family - - - 0.00000000000000000000000000000000000000000000000000006745 207.0
HKD1_k127_2822604_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000005569 158.0
HKD1_k127_2822604_4 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000001506 152.0
HKD1_k127_2822604_5 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000001268 79.0
HKD1_k127_28518_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 565.0
HKD1_k127_28518_1 NADPH quinone reductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 535.0
HKD1_k127_28518_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 478.0
HKD1_k127_28518_3 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 364.0
HKD1_k127_28518_4 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 352.0
HKD1_k127_28518_5 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 313.0
HKD1_k127_28518_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000875 218.0
HKD1_k127_28518_7 Elongation factor SelB, winged helix K03833 - - 0.000000003503 60.0
HKD1_k127_2893917_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 565.0
HKD1_k127_2893917_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 537.0
HKD1_k127_2893917_10 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000002121 258.0
HKD1_k127_2893917_14 L-lactate permease K03303 - - 0.0000000000000000000000000000000002012 139.0
HKD1_k127_2893917_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000004243 106.0
HKD1_k127_2893917_16 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000004915 119.0
HKD1_k127_2893917_17 decarboxylase K01607 - 4.1.1.44 0.0000000001032 70.0
HKD1_k127_2893917_2 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 471.0
HKD1_k127_2893917_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 457.0
HKD1_k127_2893917_4 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 407.0
HKD1_k127_2893917_5 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 391.0
HKD1_k127_2893917_6 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 368.0
HKD1_k127_2893917_7 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 354.0
HKD1_k127_2893917_8 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 337.0
HKD1_k127_2893917_9 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
HKD1_k127_297035_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 608.0
HKD1_k127_297035_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 526.0
HKD1_k127_297035_2 Helix-turn-helix domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 362.0
HKD1_k127_297035_3 Protein of unknown function (DUF1415) K09941 - - 0.00000000000000000000000000000000000000000000000000000000005222 211.0
HKD1_k127_297035_4 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000006256 175.0
HKD1_k127_297035_6 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000004331 86.0
HKD1_k127_2975902_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1181.0
HKD1_k127_2975902_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.742e-270 841.0
HKD1_k127_2975902_10 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 351.0
HKD1_k127_2975902_11 methyltransferase K10218 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 318.0
HKD1_k127_2975902_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 317.0
HKD1_k127_2975902_13 PFAM Helix-turn-helix, type 11 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 293.0
HKD1_k127_2975902_14 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000004427 260.0
HKD1_k127_2975902_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000005332 271.0
HKD1_k127_2975902_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000001012 248.0
HKD1_k127_2975902_17 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000008091 253.0
HKD1_k127_2975902_18 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000009667 231.0
HKD1_k127_2975902_19 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000001297 219.0
HKD1_k127_2975902_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 511.0
HKD1_k127_2975902_20 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000000000000000000000000000000000989 230.0
HKD1_k127_2975902_21 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000331 199.0
HKD1_k127_2975902_22 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000003372 157.0
HKD1_k127_2975902_23 - - - - 0.00000000000000000000000000001671 129.0
HKD1_k127_2975902_24 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000004844 79.0
HKD1_k127_2975902_25 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.00000000001919 75.0
HKD1_k127_2975902_26 Lipopolysaccharide assembly protein A domain K08992 - - 0.000146 48.0
HKD1_k127_2975902_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 499.0
HKD1_k127_2975902_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 470.0
HKD1_k127_2975902_5 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 440.0
HKD1_k127_2975902_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 430.0
HKD1_k127_2975902_7 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 426.0
HKD1_k127_2975902_8 DNA recombination protein RmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 406.0
HKD1_k127_2975902_9 Psort location Cytoplasmic, score 8.96 K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
HKD1_k127_2979154_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 471.0
HKD1_k127_2979154_1 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 320.0
HKD1_k127_2979154_2 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009904 250.0
HKD1_k127_2979154_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000007001 208.0
HKD1_k127_2979154_4 membrane - - - 0.0000000000000000000000000000000000000001729 153.0
HKD1_k127_2979154_5 metallopeptidase activity - - - 0.0000000000000000000000000000000007734 137.0
HKD1_k127_2988559_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 497.0
HKD1_k127_2988559_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 422.0
HKD1_k127_2988559_2 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 406.0
HKD1_k127_2988559_3 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 323.0
HKD1_k127_2988559_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 315.0
HKD1_k127_2988559_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000055 243.0
HKD1_k127_2988559_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000006875 123.0
HKD1_k127_2988559_7 protein, YerC YecD - - - 0.00000000000000000000000001007 112.0
HKD1_k127_2988559_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000002424 58.0
HKD1_k127_3059177_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1335.0
HKD1_k127_3059177_1 DNA ligase (ATP) activity K01971 - 6.5.1.1 2.557e-266 848.0
HKD1_k127_3059177_10 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000015 218.0
HKD1_k127_3059177_11 TPR repeat - - - 0.0000000000000000000000000000000000000000000000008929 187.0
HKD1_k127_3059177_12 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000001814 102.0
HKD1_k127_3059177_13 MerC mercury resistance protein - - - 0.0000000000000000005266 93.0
HKD1_k127_3059177_14 Ammonium Transporter K03320 - - 0.000000000002719 67.0
HKD1_k127_3059177_2 Squalene phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 400.0
HKD1_k127_3059177_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 313.0
HKD1_k127_3059177_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 300.0
HKD1_k127_3059177_5 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 289.0
HKD1_k127_3059177_6 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000858 293.0
HKD1_k127_3059177_7 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
HKD1_k127_3059177_8 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008431 291.0
HKD1_k127_3059177_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000004713 218.0
HKD1_k127_3061936_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 9.429e-214 700.0
HKD1_k127_3061936_1 Protein kinase domain K12132 - 2.7.11.1 6.434e-205 672.0
HKD1_k127_3061936_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 385.0
HKD1_k127_3061936_3 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005289 286.0
HKD1_k127_3061936_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004772 273.0
HKD1_k127_3061936_5 Helicase K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000025 240.0
HKD1_k127_3061936_6 Protein of unknown function (DUF423) - - - 0.000003876 52.0
HKD1_k127_3077340_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.962e-234 733.0
HKD1_k127_3077340_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.435e-228 717.0
HKD1_k127_3077340_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 561.0
HKD1_k127_3077340_3 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 512.0
HKD1_k127_3077340_4 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 479.0
HKD1_k127_3077340_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 444.0
HKD1_k127_3077340_6 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 369.0
HKD1_k127_3077340_7 Peptidase family M48 - - - 0.000000000000000000003294 98.0
HKD1_k127_3077709_0 Hexosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 406.0
HKD1_k127_3077709_1 glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 362.0
HKD1_k127_3077709_2 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 336.0
HKD1_k127_3077709_3 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 310.0
HKD1_k127_3077709_4 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 319.0
HKD1_k127_3077709_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000119 146.0
HKD1_k127_3077709_6 rRNA processing K21402 - - 0.00000000004677 72.0
HKD1_k127_3077709_7 Acyltransferase family - - - 0.00000002394 56.0
HKD1_k127_3081045_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 5.546e-210 660.0
HKD1_k127_3081045_1 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003166 270.0
HKD1_k127_3081045_10 - - - - 0.00000000001784 75.0
HKD1_k127_3081045_11 Protein involved in meta-pathway of phenol degradation - - - 0.00000000001952 76.0
HKD1_k127_3081045_12 - - - - 0.0000000000858 68.0
HKD1_k127_3081045_13 - - - - 0.0004832 49.0
HKD1_k127_3081045_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000722 253.0
HKD1_k127_3081045_3 signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001035 257.0
HKD1_k127_3081045_4 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000000000000091 246.0
HKD1_k127_3081045_5 COG2030 Acyl dehydratase - - - 0.0000000000000000000000000000000000000000000000000005298 192.0
HKD1_k127_3081045_6 response regulator K15012 - - 0.0000000000000000000000000000000000000000000000001183 182.0
HKD1_k127_3081045_7 - - - - 0.000000000000000000000001299 108.0
HKD1_k127_3081045_8 - - - - 0.000000000000000000002125 108.0
HKD1_k127_3081045_9 Protein of unknown function (DUF1161) - - - 0.0000000000000000004198 89.0
HKD1_k127_3106239_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 2.278e-318 994.0
HKD1_k127_3106239_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 4.411e-225 719.0
HKD1_k127_3106239_10 Belongs to the GMC oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 542.0
HKD1_k127_3106239_11 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 507.0
HKD1_k127_3106239_12 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 436.0
HKD1_k127_3106239_13 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 428.0
HKD1_k127_3106239_14 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 402.0
HKD1_k127_3106239_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 366.0
HKD1_k127_3106239_16 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 323.0
HKD1_k127_3106239_17 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000172 289.0
HKD1_k127_3106239_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 261.0
HKD1_k127_3106239_19 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 256.0
HKD1_k127_3106239_2 SbmA/BacA-like family - - - 1.089e-217 691.0
HKD1_k127_3106239_20 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001502 254.0
HKD1_k127_3106239_21 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000243 265.0
HKD1_k127_3106239_22 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000005974 245.0
HKD1_k127_3106239_23 Cupin - - - 0.0000000000000000000000000000000000000000000000000004757 188.0
HKD1_k127_3106239_24 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000001675 185.0
HKD1_k127_3106239_25 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000003909 171.0
HKD1_k127_3106239_26 Major facilitator Superfamily K08195 - - 0.00000000000000000000000000000000306 137.0
HKD1_k127_3106239_28 - - - - 0.00000000000000000001199 97.0
HKD1_k127_3106239_29 - - - - 0.00000000000000000001251 103.0
HKD1_k127_3106239_3 SbmA/BacA-like family - - - 1.224e-211 680.0
HKD1_k127_3106239_30 - - - - 0.000000000000000008516 89.0
HKD1_k127_3106239_31 Domain of unknown function (DUF4440) - - - 0.00000000000009916 79.0
HKD1_k127_3106239_32 MacB-like periplasmic core domain - - - 0.000000000003047 70.0
HKD1_k127_3106239_33 TonB-dependent receptor K02014,K02456,K02457,K02458,K10926,K10930,K10931 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840 - 0.000000000004726 79.0
HKD1_k127_3106239_34 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000000000004726 79.0
HKD1_k127_3106239_36 Belongs to the SlyX family K03745 - - 0.00009075 51.0
HKD1_k127_3106239_37 - - - - 0.0001462 54.0
HKD1_k127_3106239_4 Putative glucoamylase - - - 3.934e-210 662.0
HKD1_k127_3106239_5 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 2.786e-208 652.0
HKD1_k127_3106239_6 Protein of unknown function (DUF1587) - - - 3.668e-196 638.0
HKD1_k127_3106239_7 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 651.0
HKD1_k127_3106239_8 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 587.0
HKD1_k127_3106239_9 ABC transporter C-terminal domain K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 619.0
HKD1_k127_3121022_0 TIGRFAM FeS assembly protein SufB K09014 - - 1.155e-266 835.0
HKD1_k127_3121022_1 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 355.0
HKD1_k127_3121022_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 336.0
HKD1_k127_3121022_3 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 318.0
HKD1_k127_3121022_4 Redoxin K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000005114 199.0
HKD1_k127_3121022_5 PFAM Amino acid-binding ACT K03567 - - 0.00000000000000000000000000000000000000000000000000001048 197.0
HKD1_k127_3121022_6 transcriptional regulator - - - 0.00000000000000000000000000000000001124 141.0
HKD1_k127_3152624_0 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 533.0
HKD1_k127_3152624_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 504.0
HKD1_k127_3152624_10 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0003266 51.0
HKD1_k127_3152624_2 von Willebrand factor, type A K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 412.0
HKD1_k127_3152624_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 353.0
HKD1_k127_3152624_4 response regulator receiver K07776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 315.0
HKD1_k127_3152624_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000858 129.0
HKD1_k127_3152624_6 - - - - 0.000000000000000000000000000004139 127.0
HKD1_k127_3152624_7 PFAM PspA IM30 - - - 0.00000000000000000000000000001078 127.0
HKD1_k127_3152624_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000001292 68.0
HKD1_k127_3152624_9 PIN domain K07064 - - 0.000000002483 66.0
HKD1_k127_3181582_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 486.0
HKD1_k127_3181582_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 449.0
HKD1_k127_3181582_3 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 350.0
HKD1_k127_3181582_4 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000003439 249.0
HKD1_k127_3181582_5 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000001163 236.0
HKD1_k127_3181582_6 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000000000000002286 147.0
HKD1_k127_319012_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1203.0
HKD1_k127_319012_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.459e-234 739.0
HKD1_k127_319012_10 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 432.0
HKD1_k127_319012_11 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 405.0
HKD1_k127_319012_12 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 371.0
HKD1_k127_319012_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 323.0
HKD1_k127_319012_14 polyphosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 313.0
HKD1_k127_319012_15 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 316.0
HKD1_k127_319012_16 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 327.0
HKD1_k127_319012_17 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 291.0
HKD1_k127_319012_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
HKD1_k127_319012_19 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001242 267.0
HKD1_k127_319012_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 607.0
HKD1_k127_319012_20 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009534 261.0
HKD1_k127_319012_21 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000008627 267.0
HKD1_k127_319012_22 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001799 250.0
HKD1_k127_319012_23 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000002332 238.0
HKD1_k127_319012_24 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000002239 234.0
HKD1_k127_319012_25 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001565 235.0
HKD1_k127_319012_26 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000002757 231.0
HKD1_k127_319012_27 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000005125 196.0
HKD1_k127_319012_28 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000149 181.0
HKD1_k127_319012_29 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000001011 172.0
HKD1_k127_319012_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 567.0
HKD1_k127_319012_30 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000007318 182.0
HKD1_k127_319012_31 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000001736 165.0
HKD1_k127_319012_32 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000022 138.0
HKD1_k127_319012_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000004501 148.0
HKD1_k127_319012_34 COG2927 DNA polymerase III, chi subunit K02339 GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 0.00000000000000000000000000000000006039 138.0
HKD1_k127_319012_35 pfam rdd - - - 0.0000000000000000000000000000005887 127.0
HKD1_k127_319012_36 protein conserved in bacteria K09938 - - 0.0000000000000000000000000001793 128.0
HKD1_k127_319012_37 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000005005 123.0
HKD1_k127_319012_38 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000008522 116.0
HKD1_k127_319012_39 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000001469 96.0
HKD1_k127_319012_4 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 513.0
HKD1_k127_319012_40 acylphosphatase K01512 - 3.6.1.7 0.0000000000000000502 88.0
HKD1_k127_319012_41 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000005708 81.0
HKD1_k127_319012_43 protein conserved in bacteria K09937 - - 0.000000001415 61.0
HKD1_k127_319012_45 - - - - 0.0000214 53.0
HKD1_k127_319012_47 FeoA K04758 - - 0.000104 48.0
HKD1_k127_319012_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 482.0
HKD1_k127_319012_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 477.0
HKD1_k127_319012_7 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 465.0
HKD1_k127_319012_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 432.0
HKD1_k127_319012_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 427.0
HKD1_k127_3197587_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 7.817e-259 808.0
HKD1_k127_3197587_1 Bacterial protein of unknown function (DUF853) K06915 - - 1.485e-207 656.0
HKD1_k127_3197587_2 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000007921 253.0
HKD1_k127_3197587_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000008042 213.0
HKD1_k127_3197587_4 SnoaL-like domain - - - 0.000000001591 65.0
HKD1_k127_3197587_5 DUF218 domain - - - 0.000006434 48.0
HKD1_k127_3197587_6 calcium-dependent protein kinase K13412 GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004683,GO:0005488,GO:0005515,GO:0005516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0008152,GO:0009555,GO:0009628,GO:0009719,GO:0009725,GO:0009737,GO:0009738,GO:0009755,GO:0009931,GO:0009987,GO:0010033,GO:0010152,GO:0010857,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0021700,GO:0023052,GO:0032501,GO:0032502,GO:0032870,GO:0033993,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046777,GO:0048229,GO:0048518,GO:0048583,GO:0048584,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071215,GO:0071229,GO:0071310,GO:0071396,GO:0071495,GO:0071704,GO:0071944,GO:0080134,GO:0097305,GO:0097306,GO:0140096,GO:1901564,GO:1901700,GO:1901701,GO:1902584,GO:2000070 2.7.11.1 0.00002967 53.0
HKD1_k127_3258823_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 1.84e-274 863.0
HKD1_k127_3258823_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.246e-236 758.0
HKD1_k127_3258823_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 628.0
HKD1_k127_3258823_3 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003283 259.0
HKD1_k127_3258823_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008861 247.0
HKD1_k127_3258823_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000001228 241.0
HKD1_k127_3258823_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000359 224.0
HKD1_k127_3258823_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000231 216.0
HKD1_k127_3273447_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 5.049e-225 713.0
HKD1_k127_3273447_1 Aldehyde dehydrogenase family K21802 - 1.2.1.67 8.557e-197 626.0
HKD1_k127_3273447_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 411.0
HKD1_k127_3273447_3 Cardiolipin synthase K06132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 312.0
HKD1_k127_3273447_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000862 190.0
HKD1_k127_3273447_5 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000001147 130.0
HKD1_k127_3277712_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 4.331e-195 617.0
HKD1_k127_3277712_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 571.0
HKD1_k127_3277712_10 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000002692 129.0
HKD1_k127_3277712_11 Protein of unknown function (DUF2905) - - - 0.00000000000000000000649 94.0
HKD1_k127_3277712_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 522.0
HKD1_k127_3277712_3 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 511.0
HKD1_k127_3277712_4 chorismate binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 509.0
HKD1_k127_3277712_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 417.0
HKD1_k127_3277712_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001018 310.0
HKD1_k127_3277712_7 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001251 252.0
HKD1_k127_3277712_8 Tetratricopeptide repeat K03671,K05838 - - 0.00000000000000000000000000000000000000000000000000000001209 211.0
HKD1_k127_3277712_9 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000003563 140.0
HKD1_k127_3292666_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.187e-308 954.0
HKD1_k127_3292666_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.084e-263 825.0
HKD1_k127_3292666_10 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 390.0
HKD1_k127_3292666_11 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 355.0
HKD1_k127_3292666_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 347.0
HKD1_k127_3292666_13 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 296.0
HKD1_k127_3292666_14 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 266.0
HKD1_k127_3292666_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000002831 175.0
HKD1_k127_3292666_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000007201 135.0
HKD1_k127_3292666_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000005277 134.0
HKD1_k127_3292666_18 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000005555 138.0
HKD1_k127_3292666_19 protein conserved in bacteria K09948 - - 0.0000000000000000000000000000000008188 138.0
HKD1_k127_3292666_2 Flavin containing amine oxidoreductase - - - 2.444e-214 683.0
HKD1_k127_3292666_20 belongs to the Fur family K09826 - - 0.00000000000000000000000000000002252 134.0
HKD1_k127_3292666_21 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000003365 121.0
HKD1_k127_3292666_22 - - - - 0.00000000000000000000001635 117.0
HKD1_k127_3292666_23 Type II transport protein GspH K08084 - - 0.00000000000000000000004189 106.0
HKD1_k127_3292666_24 - - - - 0.0000000000000000000829 96.0
HKD1_k127_3292666_25 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000000000000000002654 104.0
HKD1_k127_3292666_26 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000006636 87.0
HKD1_k127_3292666_27 Type IV Pilus-assembly protein W K02672 - - 0.000000000001289 81.0
HKD1_k127_3292666_29 COG4967 Tfp pilus assembly protein PilV - - - 0.000000000007982 78.0
HKD1_k127_3292666_3 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 613.0
HKD1_k127_3292666_30 Type II transport protein GspH K08084 - - 0.00000004534 63.0
HKD1_k127_3292666_31 Pilus assembly protein PilX K02673 - - 0.00002123 55.0
HKD1_k127_3292666_32 - - - - 0.00007437 47.0
HKD1_k127_3292666_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 515.0
HKD1_k127_3292666_5 MatE - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 507.0
HKD1_k127_3292666_6 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 501.0
HKD1_k127_3292666_7 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 482.0
HKD1_k127_3292666_8 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 485.0
HKD1_k127_3292666_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 435.0
HKD1_k127_3293626_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1061.0
HKD1_k127_3293626_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 9.501e-214 670.0
HKD1_k127_3293626_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 349.0
HKD1_k127_3293626_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 333.0
HKD1_k127_3293626_4 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000002378 147.0
HKD1_k127_3293626_5 - - - - 0.0004646 47.0
HKD1_k127_3331597_0 Bacterial protein of unknown function (DUF885) - - - 6.107e-228 721.0
HKD1_k127_3331597_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 2.372e-222 705.0
HKD1_k127_3331597_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.165e-201 657.0
HKD1_k127_3331597_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 434.0
HKD1_k127_3331597_4 Aldehyde dehydrogenase family K13922,K18119 - 1.2.1.76,1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 385.0
HKD1_k127_3331597_5 Putative vitamin uptake transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 358.0
HKD1_k127_3331597_6 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000007494 209.0
HKD1_k127_3331597_7 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000004192 190.0
HKD1_k127_3340407_0 Aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 4.513e-236 737.0
HKD1_k127_3340407_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 2.121e-205 653.0
HKD1_k127_3340407_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 278.0
HKD1_k127_3340407_3 - - - - 0.0000000000000000000000000000000000000000000109 175.0
HKD1_k127_3340407_4 - - - - 0.000000000000000000000000000000000000000897 155.0
HKD1_k127_3357791_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.921e-218 687.0
HKD1_k127_3357791_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 326.0
HKD1_k127_3357791_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000001201 243.0
HKD1_k127_3357791_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000004404 236.0
HKD1_k127_3357791_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002748 186.0
HKD1_k127_3357791_5 Colicin v production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000000000000000000695 119.0
HKD1_k127_3478991_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 505.0
HKD1_k127_3478991_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 438.0
HKD1_k127_3478991_10 Ion channel - - - 0.0000000000000000000000000000000001556 149.0
HKD1_k127_3478991_11 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000001619 133.0
HKD1_k127_3478991_12 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000466 120.0
HKD1_k127_3478991_13 - - - - 0.00000000004973 68.0
HKD1_k127_3478991_14 TonB C terminal K03646 - - 0.00000005244 65.0
HKD1_k127_3478991_15 Metallo-beta-lactamase superfamily - - - 0.0000004862 60.0
HKD1_k127_3478991_16 - - - - 0.00007066 46.0
HKD1_k127_3478991_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 318.0
HKD1_k127_3478991_3 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 314.0
HKD1_k127_3478991_4 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008763 247.0
HKD1_k127_3478991_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000001771 202.0
HKD1_k127_3478991_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000002063 175.0
HKD1_k127_3478991_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000001299 168.0
HKD1_k127_3478991_8 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000001754 155.0
HKD1_k127_3478991_9 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000002201 156.0
HKD1_k127_3516044_0 Binding-protein-dependent transport systems inner membrane component K02050 - - 1.657e-219 695.0
HKD1_k127_3516044_1 ABC transporter K02049 - - 2.804e-197 623.0
HKD1_k127_3516044_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 508.0
HKD1_k127_3516044_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 324.0
HKD1_k127_3516044_4 Secreted protein, containing von Willebrand factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 295.0
HKD1_k127_3516044_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000001774 197.0
HKD1_k127_3516044_6 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.000000000000000000000000000000006312 131.0
HKD1_k127_3516044_7 - - - - 0.0000000000000000000000001781 123.0
HKD1_k127_3516044_8 OmpA family - - - 0.000000000000000002275 95.0
HKD1_k127_3516044_9 COG1716 FOG FHA domain - - - 0.0001033 55.0
HKD1_k127_3530008_0 synthetase K01908 - 6.2.1.17 6.438e-273 852.0
HKD1_k127_3530008_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 3.288e-215 694.0
HKD1_k127_3530008_10 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 378.0
HKD1_k127_3530008_11 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 353.0
HKD1_k127_3530008_12 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 333.0
HKD1_k127_3530008_13 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002235 294.0
HKD1_k127_3530008_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
HKD1_k127_3530008_15 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002735 262.0
HKD1_k127_3530008_16 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001206 247.0
HKD1_k127_3530008_17 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000006666 240.0
HKD1_k127_3530008_18 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000005997 233.0
HKD1_k127_3530008_19 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000002229 196.0
HKD1_k127_3530008_2 DNA topological change K03168 - 5.99.1.2 6.303e-212 685.0
HKD1_k127_3530008_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000273 181.0
HKD1_k127_3530008_21 - - - - 0.000000000000000000000000000000037 139.0
HKD1_k127_3530008_22 - - - - 0.00000000000000000000000001316 121.0
HKD1_k127_3530008_23 MAPEG family - - - 0.00000000000000000000000004252 119.0
HKD1_k127_3530008_24 - - - - 0.0000000000000000000000001813 112.0
HKD1_k127_3530008_26 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000001995 106.0
HKD1_k127_3530008_27 - - - - 0.00000000000000000286 91.0
HKD1_k127_3530008_28 secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.0000000000000000179 97.0
HKD1_k127_3530008_29 - - - - 0.0000000000000001673 91.0
HKD1_k127_3530008_3 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 585.0
HKD1_k127_3530008_30 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.00000002173 61.0
HKD1_k127_3530008_31 SnoaL-like domain - - - 0.000006198 55.0
HKD1_k127_3530008_4 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 520.0
HKD1_k127_3530008_5 Belongs to the citrate synthase family K01659 GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 511.0
HKD1_k127_3530008_6 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 416.0
HKD1_k127_3530008_7 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 413.0
HKD1_k127_3530008_8 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 419.0
HKD1_k127_3530008_9 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 394.0
HKD1_k127_3661804_0 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 330.0
HKD1_k127_3661804_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001592 289.0
HKD1_k127_3661804_2 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001602 251.0
HKD1_k127_3661804_3 - - - - 0.00000000000000000000000000000003458 134.0
HKD1_k127_3661804_4 KR domain - - - 0.00000000000000000000000000000003545 128.0
HKD1_k127_3661804_5 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000002071 94.0
HKD1_k127_3661804_6 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000001341 76.0
HKD1_k127_368935_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 591.0
HKD1_k127_368935_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 436.0
HKD1_k127_368935_2 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 304.0
HKD1_k127_368935_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 304.0
HKD1_k127_368935_4 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000003844 123.0
HKD1_k127_3689644_0 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000001155 230.0
HKD1_k127_3689644_1 Signal peptidase, peptidase S26 - - - 0.000000000000000000000000000000000000000000000000000000000000000005927 231.0
HKD1_k127_3689644_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000231 226.0
HKD1_k127_3689644_3 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000001176 180.0
HKD1_k127_3689644_4 Protein conserved in bacteria K09796 - - 0.00000000000000000000005649 106.0
HKD1_k127_3689644_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000007986 102.0
HKD1_k127_3689644_6 Polymer-forming cytoskeletal - - - 0.000000000181 74.0
HKD1_k127_3689644_7 NlpE C-terminal OB domain K06079 - - 0.00000004199 65.0
HKD1_k127_3689644_8 pathogenesis - - - 0.000001378 60.0
HKD1_k127_3694439_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 419.0
HKD1_k127_3694439_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 363.0
HKD1_k127_3694439_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001408 231.0
HKD1_k127_3694439_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000001201 220.0
HKD1_k127_3694439_4 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.0000000000000000000000000000000000000000005489 159.0
HKD1_k127_3694439_5 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000009108 102.0
HKD1_k127_3694439_6 NifU-like N terminal domain - - - 0.00000115 55.0
HKD1_k127_3698395_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 351.0
HKD1_k127_3698395_1 - - - - 0.00000000000000000000000000000000000000000000000001257 203.0
HKD1_k127_3698395_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000002393 175.0
HKD1_k127_3698395_3 - - - - 0.00000000000000000000000272 106.0
HKD1_k127_3698395_4 - - - - 0.00000000000000006319 94.0
HKD1_k127_3748594_1 belongs to the aldehyde dehydrogenase family K00146 - 1.2.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 574.0
HKD1_k127_3748594_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0000000000000000000000000000000000000000000000000000001854 207.0
HKD1_k127_3748594_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000005619 175.0
HKD1_k127_3748594_12 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000003537 146.0
HKD1_k127_3748594_13 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.000000000000000000000000000005534 121.0
HKD1_k127_3748594_14 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000003513 128.0
HKD1_k127_3748594_15 Domain of unknown function (DUF4136) - - - 0.000000001158 67.0
HKD1_k127_3748594_16 GtrA-like protein - - - 0.0000001472 59.0
HKD1_k127_3748594_2 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 403.0
HKD1_k127_3748594_3 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 374.0
HKD1_k127_3748594_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 296.0
HKD1_k127_3748594_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002092 277.0
HKD1_k127_3748594_6 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002307 267.0
HKD1_k127_3748594_7 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005094 269.0
HKD1_k127_3748594_8 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002022 268.0
HKD1_k127_3748594_9 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
HKD1_k127_3761461_0 ATPase, P-type K01531 - 3.6.3.2 0.0 1047.0
HKD1_k127_3761461_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.094e-248 781.0
HKD1_k127_3761461_10 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008268 276.0
HKD1_k127_3761461_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000001566 194.0
HKD1_k127_3761461_12 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000000000000000000000000000000000000000001251 174.0
HKD1_k127_3761461_13 Cytochrome c - - - 0.00000000000000000000000000003786 122.0
HKD1_k127_3761461_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000004506 121.0
HKD1_k127_3761461_15 Universal stress protein K14055 GO:0000302,GO:0001539,GO:0006928,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0033554,GO:0034599,GO:0034614,GO:0034644,GO:0035690,GO:0040011,GO:0042221,GO:0042493,GO:0042542,GO:0042710,GO:0044010,GO:0044764,GO:0046677,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071478,GO:0071482,GO:0071973,GO:0097237,GO:0097588,GO:0104004,GO:1901700,GO:1901701 - 0.0000000000000000000000001934 119.0
HKD1_k127_3761461_16 MerR HTH family regulatory protein K18997 - - 0.000000000000000001407 98.0
HKD1_k127_3761461_17 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000001273 70.0
HKD1_k127_3761461_2 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 598.0
HKD1_k127_3761461_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 523.0
HKD1_k127_3761461_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 492.0
HKD1_k127_3761461_5 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 490.0
HKD1_k127_3761461_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 426.0
HKD1_k127_3761461_7 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
HKD1_k127_3761461_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 336.0
HKD1_k127_3761461_9 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 308.0
HKD1_k127_3764227_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 492.0
HKD1_k127_3764227_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004002 285.0
HKD1_k127_3764227_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006512 257.0
HKD1_k127_3764227_3 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002846 253.0
HKD1_k127_3789721_0 sulphate transporter - - - 1.778e-206 661.0
HKD1_k127_3789721_1 Sodium/calcium exchanger protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 513.0
HKD1_k127_3789721_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 456.0
HKD1_k127_3789721_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 443.0
HKD1_k127_3789721_4 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 367.0
HKD1_k127_3789721_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 282.0
HKD1_k127_3789721_7 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000002283 128.0
HKD1_k127_3789721_8 Universal stress protein K06149 - - 0.000000000000000000000000002447 117.0
HKD1_k127_3789721_9 Cache_2 K02480 - 2.7.13.3 0.00000000000006342 82.0
HKD1_k127_381554_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1489.0
HKD1_k127_381554_1 Tetratricopeptide repeat - - - 7.103e-227 734.0
HKD1_k127_381554_10 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009289 260.0
HKD1_k127_381554_11 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000331 257.0
HKD1_k127_381554_12 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000005938 249.0
HKD1_k127_381554_13 inositol mono-phosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000000000000000008921 233.0
HKD1_k127_381554_14 - - - - 0.00000000000000000000000000000000000000000000000000000025 200.0
HKD1_k127_381554_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000001533 199.0
HKD1_k127_381554_16 protein serine/threonine phosphatase activity K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000005716 196.0
HKD1_k127_381554_17 nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000000001474 177.0
HKD1_k127_381554_18 Type VI secretion K07169,K11894,K11913 - - 0.00000000000000000000000000000000000000000007284 178.0
HKD1_k127_381554_19 Domain of unknown function (DUF1820) - - - 0.00000000000000000000000000000000000000007279 155.0
HKD1_k127_381554_2 Ammonium transporter K03320 - - 2.866e-226 708.0
HKD1_k127_381554_20 TPR repeat - - - 0.00000000000000000000000000000000001101 147.0
HKD1_k127_381554_21 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000004077 132.0
HKD1_k127_381554_22 Glutathione peroxidase - - - 0.00000000000000000000000000000006804 132.0
HKD1_k127_381554_23 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000192 134.0
HKD1_k127_381554_24 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0000000000000000000000000005665 113.0
HKD1_k127_381554_25 May be involved in recombination K03554 - - 0.00000000000000000000004048 115.0
HKD1_k127_381554_26 - - - - 0.0000000000003299 82.0
HKD1_k127_381554_27 Glutathione S-transferase K00799 - 2.5.1.18 0.0002699 44.0
HKD1_k127_381554_3 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 452.0
HKD1_k127_381554_4 MFS transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 436.0
HKD1_k127_381554_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 435.0
HKD1_k127_381554_6 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 366.0
HKD1_k127_381554_7 OmpA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 337.0
HKD1_k127_381554_8 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 317.0
HKD1_k127_381554_9 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000229 278.0
HKD1_k127_3867276_0 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 618.0
HKD1_k127_3867276_1 Carbohydrate-selective porin, OprB family K16079,K16080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 497.0
HKD1_k127_3867276_10 Glycosyl transferase, family 2 - - - 0.000000000000000000001816 108.0
HKD1_k127_3867276_11 - - - - 0.000000000000003466 88.0
HKD1_k127_3867276_12 transcriptional regulator - - - 0.000000000009593 68.0
HKD1_k127_3867276_2 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 372.0
HKD1_k127_3867276_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 327.0
HKD1_k127_3867276_4 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002835 241.0
HKD1_k127_3867276_5 - - - - 0.0000000000000000000000000000000007635 148.0
HKD1_k127_3867276_6 Ankyrin 1, erythrocytic K10380,K15502,K15503 - - 0.0000000000000000000000000000006137 139.0
HKD1_k127_3867276_7 - - - - 0.000000000000000000000000000008112 123.0
HKD1_k127_3867276_8 phospholipase Carboxylesterase - - - 0.0000000000000000000000000001668 127.0
HKD1_k127_3873324_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 599.0
HKD1_k127_3873324_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 556.0
HKD1_k127_3873324_10 VIT family - - - 0.0000000000000000000000000000000000000000000000213 181.0
HKD1_k127_3873324_11 PFAM Rhodanese domain protein - - - 0.00000000000000000000000001052 112.0
HKD1_k127_3873324_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000006006 104.0
HKD1_k127_3873324_13 cytochrome - - - 0.0000000001415 69.0
HKD1_k127_3873324_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 406.0
HKD1_k127_3873324_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 357.0
HKD1_k127_3873324_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 319.0
HKD1_k127_3873324_5 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003925 291.0
HKD1_k127_3873324_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001093 256.0
HKD1_k127_3873324_7 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
HKD1_k127_3873324_8 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000008749 229.0
HKD1_k127_3873324_9 - - - - 0.00000000000000000000000000000000000000000000000000000005796 218.0
HKD1_k127_3951393_0 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 304.0
HKD1_k127_3951393_1 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008257 288.0
HKD1_k127_3951393_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000031 181.0
HKD1_k127_3951393_3 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000001994 126.0
HKD1_k127_3951393_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000005543 106.0
HKD1_k127_3951393_5 PFAM phosphoesterase, PA-phosphatase related - - - 0.0000000000000001011 94.0
HKD1_k127_3951393_6 Permeases of the drug metabolite transporter (DMT) superfamily K12962 - - 0.0000000000000004211 88.0
HKD1_k127_3951393_7 DnaJ molecular chaperone homology domain K05516 - - 0.0000008978 54.0
HKD1_k127_3951393_8 Small Multidrug Resistance protein - - - 0.000003124 58.0
HKD1_k127_3953174_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 587.0
HKD1_k127_3953174_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 573.0
HKD1_k127_3953174_10 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 312.0
HKD1_k127_3953174_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.0000000000000000000000000000000000000002778 163.0
HKD1_k127_3953174_12 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000002201 130.0
HKD1_k127_3953174_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000683 81.0
HKD1_k127_3953174_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 492.0
HKD1_k127_3953174_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 422.0
HKD1_k127_3953174_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 405.0
HKD1_k127_3953174_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 395.0
HKD1_k127_3953174_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 404.0
HKD1_k127_3953174_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 375.0
HKD1_k127_3953174_8 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 350.0
HKD1_k127_3953174_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 313.0
HKD1_k127_3954225_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1223.0
HKD1_k127_3954225_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 541.0
HKD1_k127_3954225_10 - - - - 0.00000000000000000000000000000000000000000000000001178 186.0
HKD1_k127_3954225_11 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000005459 173.0
HKD1_k127_3954225_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000003389 125.0
HKD1_k127_3954225_13 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000364 87.0
HKD1_k127_3954225_2 PFAM PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 412.0
HKD1_k127_3954225_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 387.0
HKD1_k127_3954225_4 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 365.0
HKD1_k127_3954225_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 305.0
HKD1_k127_3954225_6 Transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 290.0
HKD1_k127_3954225_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005284 271.0
HKD1_k127_3954225_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000001471 248.0
HKD1_k127_3954225_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000001809 208.0
HKD1_k127_4022986_0 Multi-copper - - - 5.602e-255 808.0
HKD1_k127_4022986_1 TonB dependent receptor - - - 4.19e-217 694.0
HKD1_k127_4022986_10 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002827 283.0
HKD1_k127_4022986_11 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000005318 258.0
HKD1_k127_4022986_12 copper resistance K07233 - - 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
HKD1_k127_4022986_13 PFAM NnrU protein - - - 0.0000000000000000000000000000000000000000000000000004663 190.0
HKD1_k127_4022986_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000008712 188.0
HKD1_k127_4022986_15 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.000000000000000000000000000000000000000000000000002316 189.0
HKD1_k127_4022986_16 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000000000001578 163.0
HKD1_k127_4022986_17 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000456 180.0
HKD1_k127_4022986_18 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001499 144.0
HKD1_k127_4022986_19 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000009252 138.0
HKD1_k127_4022986_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 611.0
HKD1_k127_4022986_20 - - - - 0.000000000000000000000000000002638 128.0
HKD1_k127_4022986_21 Protein of unknown function (DUF1090) - - - 0.00000000000000000000000005176 116.0
HKD1_k127_4022986_22 - - - - 0.0000000000000000000000001158 116.0
HKD1_k127_4022986_23 - - - - 0.000000000000000000000000321 111.0
HKD1_k127_4022986_24 Glycosyl transferases group 1 - - - 0.0000000000000000000000006563 114.0
HKD1_k127_4022986_25 - - - - 0.00000000000000000000004737 110.0
HKD1_k127_4022986_26 - - - - 0.0000000000000000002299 98.0
HKD1_k127_4022986_27 - - - - 0.00000000000000002659 88.0
HKD1_k127_4022986_28 - - - - 0.00000000000000009118 91.0
HKD1_k127_4022986_3 Uncharacterised MFS-type transporter YbfB K05548,K05819,K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 454.0
HKD1_k127_4022986_30 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000103 69.0
HKD1_k127_4022986_32 CAAX protease self-immunity - - - 0.000000237 64.0
HKD1_k127_4022986_33 - - - - 0.0003865 49.0
HKD1_k127_4022986_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 423.0
HKD1_k127_4022986_5 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 436.0
HKD1_k127_4022986_6 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 377.0
HKD1_k127_4022986_7 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 332.0
HKD1_k127_4022986_8 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 317.0
HKD1_k127_4022986_9 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 305.0
HKD1_k127_4032708_0 Monomeric isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1048.0
HKD1_k127_4032708_1 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 5.62e-235 734.0
HKD1_k127_4032708_10 Putative regulatory protein - - - 0.0000006007 57.0
HKD1_k127_4032708_11 WD domain, G-beta repeat - - - 0.00005986 55.0
HKD1_k127_4032708_2 PFAM glycine cleavage T protein (aminomethyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 614.0
HKD1_k127_4032708_3 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 550.0
HKD1_k127_4032708_4 short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 548.0
HKD1_k127_4032708_5 PFAM Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 339.0
HKD1_k127_4032708_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000004845 195.0
HKD1_k127_4032708_7 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000007749 173.0
HKD1_k127_4032708_8 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000002367 142.0
HKD1_k127_4032708_9 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000124 112.0
HKD1_k127_410629_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 349.0
HKD1_k127_410629_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 340.0
HKD1_k127_410629_2 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000457 272.0
HKD1_k127_410629_3 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000001836 186.0
HKD1_k127_410629_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000001394 117.0
HKD1_k127_4181735_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 6.56e-222 702.0
HKD1_k127_4181735_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005221 248.0
HKD1_k127_4181735_2 universal stress protein K14055 - - 0.000000000000000000000000000000000000000000000000002436 196.0
HKD1_k127_4181735_3 Histidine kinase K14986 - 2.7.13.3 0.000000000000000001188 89.0
HKD1_k127_421260_0 2 iron, 2 sulfur cluster binding - - - 0.0 1612.0
HKD1_k127_421260_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1344.0
HKD1_k127_421260_10 Cytochrome P460 - - - 0.00000000000000000000000000000000000000002967 166.0
HKD1_k127_421260_11 LemA family K03744 - - 0.00000000000000000000000000000000000367 155.0
HKD1_k127_421260_12 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000006107 108.0
HKD1_k127_421260_13 YCII-related domain - - - 0.000000000000000335 82.0
HKD1_k127_421260_14 - - - - 0.00000000000008845 77.0
HKD1_k127_421260_2 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 0.0 1103.0
HKD1_k127_421260_3 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 536.0
HKD1_k127_421260_4 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 538.0
HKD1_k127_421260_5 Pyrogallol hydroxytransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 328.0
HKD1_k127_421260_6 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 297.0
HKD1_k127_421260_7 Acid phosphatase homologues K09474 - 3.1.3.2 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
HKD1_k127_421260_8 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000724 216.0
HKD1_k127_421260_9 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000001457 199.0
HKD1_k127_4219598_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1272.0
HKD1_k127_4219598_1 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 536.0
HKD1_k127_4219598_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000022 216.0
HKD1_k127_4219598_3 Outer membrane efflux protein K15725 - - 0.0000001258 65.0
HKD1_k127_422154_0 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 481.0
HKD1_k127_422154_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001742 263.0
HKD1_k127_422154_2 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
HKD1_k127_422154_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002446 250.0
HKD1_k127_422154_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000007975 220.0
HKD1_k127_422154_5 Transposase zinc-binding domain - - - 0.00000000000000000000000000000000000000000000000003804 186.0
HKD1_k127_422154_6 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000003153 93.0
HKD1_k127_4253694_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1530.0
HKD1_k127_4253694_1 COG4993 Glucose dehydrogenase - - - 1.811e-210 675.0
HKD1_k127_4253694_10 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 407.0
HKD1_k127_4253694_11 Prolyl oligopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 385.0
HKD1_k127_4253694_12 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 365.0
HKD1_k127_4253694_13 Retinal pigment epithelial membrane protein K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 350.0
HKD1_k127_4253694_14 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 318.0
HKD1_k127_4253694_15 Glutathione S-transferase, N-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 308.0
HKD1_k127_4253694_16 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006333 268.0
HKD1_k127_4253694_17 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006646 263.0
HKD1_k127_4253694_18 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000111 206.0
HKD1_k127_4253694_19 - - - - 0.00000000000000000000000000000000000000000000000000001726 199.0
HKD1_k127_4253694_2 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 501.0
HKD1_k127_4253694_20 - - - - 0.00000000000000000000000000000000000000008121 160.0
HKD1_k127_4253694_22 COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent) K00547 - 2.1.1.10 0.000000000000000000000000000001849 133.0
HKD1_k127_4253694_23 Pkd domain containing protein K01337 - 3.4.21.50 0.00000000000000000000000000005928 136.0
HKD1_k127_4253694_24 - - - - 0.000000000000000000000000001752 120.0
HKD1_k127_4253694_25 - - - - 0.000008388 56.0
HKD1_k127_4253694_3 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 485.0
HKD1_k127_4253694_4 FAD linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 449.0
HKD1_k127_4253694_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 414.0
HKD1_k127_4253694_6 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 419.0
HKD1_k127_4253694_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 406.0
HKD1_k127_4253694_8 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 398.0
HKD1_k127_4253694_9 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
HKD1_k127_4256965_0 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 629.0
HKD1_k127_4256965_1 Transcriptional regulator - - - 0.000000000000002329 86.0
HKD1_k127_4256965_2 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.0000000005332 72.0
HKD1_k127_427719_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 3.082e-202 638.0
HKD1_k127_427719_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 509.0
HKD1_k127_427719_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000514 217.0
HKD1_k127_427719_11 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000001903 153.0
HKD1_k127_427719_12 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000004484 123.0
HKD1_k127_427719_13 there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc K02913 - - 0.0000000000000000007781 86.0
HKD1_k127_427719_2 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 394.0
HKD1_k127_427719_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 362.0
HKD1_k127_427719_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 327.0
HKD1_k127_427719_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 327.0
HKD1_k127_427719_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 304.0
HKD1_k127_427719_7 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001229 288.0
HKD1_k127_427719_8 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
HKD1_k127_427719_9 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002741 251.0
HKD1_k127_4282187_0 UPF0210 protein K09157 - - 2.225e-210 664.0
HKD1_k127_4282187_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 504.0
HKD1_k127_4282187_10 Domain of unknown function (DUF1840) - - - 0.00000000000000001388 87.0
HKD1_k127_4282187_12 - - - - 0.00001698 53.0
HKD1_k127_4282187_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 413.0
HKD1_k127_4282187_3 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000001189 249.0
HKD1_k127_4282187_4 protein domain, possibly involved in tellurite resistance - - - 0.0000000000000000000000000000000000000000000000000005446 208.0
HKD1_k127_4282187_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000588 171.0
HKD1_k127_4282187_6 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000006937 140.0
HKD1_k127_4282187_7 endonuclease activity - - - 0.0000000000000000000000000000001562 128.0
HKD1_k127_4282187_8 Belongs to the UPF0237 family K07166 - - 0.00000000000000000000000000000225 123.0
HKD1_k127_4282187_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000009013 108.0
HKD1_k127_4287731_0 ABC transporter - - - 3.767e-284 882.0
HKD1_k127_4287731_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 505.0
HKD1_k127_4287731_10 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000023 142.0
HKD1_k127_4287731_11 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000008033 55.0
HKD1_k127_4287731_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 407.0
HKD1_k127_4287731_3 PFAM histone deacetylase superfamily K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 385.0
HKD1_k127_4287731_4 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 397.0
HKD1_k127_4287731_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 371.0
HKD1_k127_4287731_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 337.0
HKD1_k127_4287731_7 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
HKD1_k127_4287731_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001287 220.0
HKD1_k127_4287731_9 STAS-like domain of unknown function (DUF4325) - - - 0.00000000000000000000000000000000000000000000000000007725 199.0
HKD1_k127_4290675_0 - - - - 1.23e-231 739.0
HKD1_k127_4290675_1 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 508.0
HKD1_k127_4290675_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000004574 187.0
HKD1_k127_4290675_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000009954 159.0
HKD1_k127_4290675_13 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.000000000000000000000000000000000008523 140.0
HKD1_k127_4290675_14 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000002453 104.0
HKD1_k127_4290675_15 - - - - 0.00000000009476 73.0
HKD1_k127_4290675_16 COG2223 Nitrate nitrite transporter K02575 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001552 75.0
HKD1_k127_4290675_17 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00004835 51.0
HKD1_k127_4290675_18 - - - - 0.0001465 55.0
HKD1_k127_4290675_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 384.0
HKD1_k127_4290675_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001106 297.0
HKD1_k127_4290675_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000296 279.0
HKD1_k127_4290675_6 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001288 272.0
HKD1_k127_4290675_7 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003514 276.0
HKD1_k127_4290675_8 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000773 246.0
HKD1_k127_4290675_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000167 239.0
HKD1_k127_4299257_0 TonB-dependent receptor plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 542.0
HKD1_k127_4299257_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 327.0
HKD1_k127_4299257_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.000000000000000000000000256 107.0
HKD1_k127_4299257_11 Choline kinase - - - 0.00000000000000001042 97.0
HKD1_k127_4299257_12 FAD binding domain - - - 0.000000000000002711 80.0
HKD1_k127_4299257_13 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000001045 76.0
HKD1_k127_4299257_14 YKOF-related Family - - - 0.0000000001177 65.0
HKD1_k127_4299257_2 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000002077 247.0
HKD1_k127_4299257_3 nicotinamide mononucleotide transporter K03811 - - 0.0000000000000000000000000000000000000000000000000001314 192.0
HKD1_k127_4299257_4 MoaC family K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000002616 193.0
HKD1_k127_4299257_5 PFAM molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000001971 187.0
HKD1_k127_4299257_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000001177 132.0
HKD1_k127_4299257_7 Auxin binding protein - - - 0.0000000000000000000000000000001005 128.0
HKD1_k127_4299257_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000007836 132.0
HKD1_k127_4299257_9 MobA-Related Protein K00087,K07141,K07402,K19190 - 1.1.1.328,1.17.1.4,2.7.7.76 0.00000000000000000000000002082 122.0
HKD1_k127_4303143_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 2.366e-225 724.0
HKD1_k127_4303143_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 395.0
HKD1_k127_4303143_2 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 368.0
HKD1_k127_4303143_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000004095 148.0
HKD1_k127_4303143_4 Peptidase family S51 - - - 0.0000000000004866 80.0
HKD1_k127_4330383_0 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 492.0
HKD1_k127_4330383_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 335.0
HKD1_k127_4330383_10 enzyme of heme biosynthesis K02496 - 2.1.1.107 0.000000000000000000000000004325 124.0
HKD1_k127_4330383_11 cytochrome - - - 0.000000000000000000000001228 112.0
HKD1_k127_4330383_12 rhamnose metabolic process - - - 0.000000000000000000005968 95.0
HKD1_k127_4330383_13 Membrane fusogenic activity K09806 - - 0.00000000000000005312 83.0
HKD1_k127_4330383_14 Domain of unknown function (DUF4124) - - - 0.0004454 49.0
HKD1_k127_4330383_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 329.0
HKD1_k127_4330383_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
HKD1_k127_4330383_4 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002032 288.0
HKD1_k127_4330383_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000005111 260.0
HKD1_k127_4330383_6 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004351 251.0
HKD1_k127_4330383_7 VirC1 protein K03496 - - 0.00000000000000000000000000000000000000000000000000000000000002631 221.0
HKD1_k127_4330383_8 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000251 203.0
HKD1_k127_4330383_9 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000002079 150.0
HKD1_k127_4405168_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 557.0
HKD1_k127_4405168_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 508.0
HKD1_k127_4405168_2 Sensors of blue-light using FAD - - - 0.0000000000000000000000000000000000000000531 155.0
HKD1_k127_4405168_3 - - - - 0.000000000000000000000000000003875 126.0
HKD1_k127_4405168_4 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000007257 83.0
HKD1_k127_4469703_0 Peptidase dimerisation domain - - - 9.529e-198 627.0
HKD1_k127_4469703_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 598.0
HKD1_k127_4469703_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000008192 175.0
HKD1_k127_4469703_11 FR47-like protein - - - 0.00000001698 66.0
HKD1_k127_4469703_12 - - - - 0.0000405 53.0
HKD1_k127_4469703_13 - - - - 0.0005654 52.0
HKD1_k127_4469703_2 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 460.0
HKD1_k127_4469703_3 Major facilitator Superfamily K03762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 391.0
HKD1_k127_4469703_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 310.0
HKD1_k127_4469703_5 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 302.0
HKD1_k127_4469703_6 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 301.0
HKD1_k127_4469703_7 Conserved Protein - - - 0.000000000000000000000000000000000000000000000000000000000006334 213.0
HKD1_k127_4469703_8 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000001908 222.0
HKD1_k127_4469703_9 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000006457 166.0
HKD1_k127_448849_0 - - - - 2.948e-210 687.0
HKD1_k127_448849_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 379.0
HKD1_k127_448849_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 362.0
HKD1_k127_448849_3 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000001385 240.0
HKD1_k127_448849_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000005788 173.0
HKD1_k127_448849_5 - - - - 0.00000000000002992 72.0
HKD1_k127_4505824_0 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 508.0
HKD1_k127_4505824_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 400.0
HKD1_k127_4505824_2 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 362.0
HKD1_k127_4505824_3 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004947 260.0
HKD1_k127_4505824_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.000000009545 59.0
HKD1_k127_4538075_0 Metallopeptidase family M24 - - - 3.312e-197 624.0
HKD1_k127_4538075_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 492.0
HKD1_k127_4538075_2 Ankyrin repeats (3 copies) - - - 0.0000000000000000007368 92.0
HKD1_k127_4538075_3 metal cluster binding - - - 0.0000000000003299 82.0
HKD1_k127_4538075_4 Alcohol dehydrogenase GroES-like domain K00001,K00055 - 1.1.1.1,1.1.1.90 0.000005509 50.0
HKD1_k127_4540539_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1061.0
HKD1_k127_4540539_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 1.81e-231 735.0
HKD1_k127_4540539_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 339.0
HKD1_k127_4540539_11 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 322.0
HKD1_k127_4540539_12 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 322.0
HKD1_k127_4540539_13 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
HKD1_k127_4540539_14 signal transduction histidine kinase K07644,K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 305.0
HKD1_k127_4540539_15 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 292.0
HKD1_k127_4540539_16 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006729 295.0
HKD1_k127_4540539_17 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009747 284.0
HKD1_k127_4540539_18 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 273.0
HKD1_k127_4540539_19 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002086 246.0
HKD1_k127_4540539_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 5.294e-207 667.0
HKD1_k127_4540539_20 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000001977 234.0
HKD1_k127_4540539_21 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000008494 212.0
HKD1_k127_4540539_22 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000002872 209.0
HKD1_k127_4540539_23 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000002521 192.0
HKD1_k127_4540539_24 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000001587 169.0
HKD1_k127_4540539_25 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000001913 172.0
HKD1_k127_4540539_26 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000002051 163.0
HKD1_k127_4540539_27 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000006125 147.0
HKD1_k127_4540539_28 Sporulation related domain - - - 0.0000000000000000000000000000006307 141.0
HKD1_k127_4540539_29 - - - - 0.000000000000000000003224 105.0
HKD1_k127_4540539_3 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 626.0
HKD1_k127_4540539_30 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000003095 95.0
HKD1_k127_4540539_31 - - - - 0.000000000002123 77.0
HKD1_k127_4540539_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 591.0
HKD1_k127_4540539_5 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 552.0
HKD1_k127_4540539_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 508.0
HKD1_k127_4540539_7 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 434.0
HKD1_k127_4540539_8 response regulator receiver K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 412.0
HKD1_k127_4540539_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 399.0
HKD1_k127_4562562_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058,K03778 - 1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 427.0
HKD1_k127_4562562_1 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 404.0
HKD1_k127_4562562_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 302.0
HKD1_k127_4562562_3 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002364 273.0
HKD1_k127_4562562_4 2Fe-2S -binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 245.0
HKD1_k127_4562562_5 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000002386 196.0
HKD1_k127_4562562_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000004475 154.0
HKD1_k127_4562562_7 - - - - 0.00000000000000000000002155 112.0
HKD1_k127_4562562_8 cytochrome - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000003864 79.0
HKD1_k127_4571258_0 Hexosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 409.0
HKD1_k127_4571258_1 glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 355.0
HKD1_k127_4571258_2 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 344.0
HKD1_k127_4571258_3 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 313.0
HKD1_k127_4571258_4 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 322.0
HKD1_k127_4571258_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000001415 140.0
HKD1_k127_4571258_6 Sulfotransferase family - - - 0.00000000003977 76.0
HKD1_k127_4571258_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00004337 55.0
HKD1_k127_4667059_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000003733 213.0
HKD1_k127_4667059_1 amidohydrolase - - - 0.000000000000000000000000000103 130.0
HKD1_k127_4667059_2 - - - - 0.000000000000001207 88.0
HKD1_k127_4680467_0 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 617.0
HKD1_k127_4680467_1 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 499.0
HKD1_k127_4680467_2 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 391.0
HKD1_k127_4680467_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 377.0
HKD1_k127_4680467_4 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000003665 161.0
HKD1_k127_4680467_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000009162 120.0
HKD1_k127_4680467_6 - - - - 0.00000000000000002995 96.0
HKD1_k127_4680467_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0003959 49.0
HKD1_k127_4693967_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 582.0
HKD1_k127_4693967_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 528.0
HKD1_k127_4693967_10 Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000007698 141.0
HKD1_k127_4693967_11 - - - - 0.00000000000000000000000002965 117.0
HKD1_k127_4693967_12 YceI-like domain - - - 0.00000000000000000000000006847 116.0
HKD1_k127_4693967_13 Protein of unknown function (DUF1249) K09920 - - 0.00000000000000000000003905 106.0
HKD1_k127_4693967_14 Type II secretory pathway component ExeA K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000004059 75.0
HKD1_k127_4693967_15 Recombinase zinc beta ribbon domain - - - 0.0000000008907 63.0
HKD1_k127_4693967_16 transposition K07483,K07497 - - 0.000009607 47.0
HKD1_k127_4693967_2 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 292.0
HKD1_k127_4693967_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
HKD1_k127_4693967_4 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007293 266.0
HKD1_k127_4693967_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000003219 246.0
HKD1_k127_4693967_6 COG1360 Flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000004018 217.0
HKD1_k127_4693967_7 - - - - 0.00000000000000000000000000000000000000000000000001791 188.0
HKD1_k127_4693967_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000001476 146.0
HKD1_k127_4693967_9 SH3 domain K07184 - - 0.00000000000000000000000000000000000008859 150.0
HKD1_k127_4712903_0 DNA helicase - - - 8.735e-309 987.0
HKD1_k127_4712903_1 LVIVD repeat - - - 2.979e-210 666.0
HKD1_k127_4712903_10 MazG-like family - - - 0.000000000000000000000000000000000000003802 154.0
HKD1_k127_4712903_11 aldo-keto reductase (NADP) activity K05275 - 1.1.1.65 0.00000000000000000000000000000000332 130.0
HKD1_k127_4712903_12 CHAD domain containing protein - - - 0.00000000000000000000000000000001385 141.0
HKD1_k127_4712903_13 - - - - 0.00000000000000000000000000000004341 137.0
HKD1_k127_4712903_14 Rossmann-like domain K06988 - 1.5.1.40 0.0000000000000000000000000003886 125.0
HKD1_k127_4712903_15 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000003226 100.0
HKD1_k127_4712903_16 Protein of unknown function (DUF3175) - - - 0.00000000000000000000004275 114.0
HKD1_k127_4712903_17 - - - - 0.000000000000000000004608 98.0
HKD1_k127_4712903_18 Protein of unknown function (DUF3667) - - - 0.0000000000000000000418 101.0
HKD1_k127_4712903_19 - - - - 0.000000000000000002226 87.0
HKD1_k127_4712903_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 622.0
HKD1_k127_4712903_20 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000001227 93.0
HKD1_k127_4712903_21 membrane - - - 0.00000000000000002177 85.0
HKD1_k127_4712903_22 - - - - 0.0000000000000001453 92.0
HKD1_k127_4712903_23 Outer Membrane Lipoprotein - - - 0.00000000000107 75.0
HKD1_k127_4712903_3 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 458.0
HKD1_k127_4712903_4 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 317.0
HKD1_k127_4712903_5 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006478 272.0
HKD1_k127_4712903_6 Cellulose biosynthesis protein BcsQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005691 254.0
HKD1_k127_4712903_7 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000008875 242.0
HKD1_k127_4712903_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000445 229.0
HKD1_k127_4712903_9 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000000000000000001191 164.0
HKD1_k127_4715287_0 DNA topological change K03168 - 5.99.1.2 1.701e-200 652.0
HKD1_k127_4715287_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 338.0
HKD1_k127_4715287_2 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000003692 158.0
HKD1_k127_4715287_3 PFAM Ankyrin repeat K06867 - - 0.00000000000000000000000000001274 136.0
HKD1_k127_474762_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.403e-231 727.0
HKD1_k127_474762_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 498.0
HKD1_k127_474762_2 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 412.0
HKD1_k127_474762_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 310.0
HKD1_k127_474762_4 PFAM Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 292.0
HKD1_k127_474762_5 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 293.0
HKD1_k127_474762_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000006109 133.0
HKD1_k127_474762_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000001258 117.0
HKD1_k127_4771947_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.039e-259 821.0
HKD1_k127_4771947_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 421.0
HKD1_k127_4771947_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000008836 256.0
HKD1_k127_4771947_3 PFAM Tetratricopeptide repeat - - - 0.00001815 49.0
HKD1_k127_4793159_0 Helicase K03724 - - 2.37e-322 1017.0
HKD1_k127_4793159_1 Protein kinase domain K12132 - 2.7.11.1 8.599e-207 677.0
HKD1_k127_4793159_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HKD1_k127_4793159_3 Inner membrane protein CreD - - - 0.0000005783 57.0
HKD1_k127_4812843_0 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 404.0
HKD1_k127_4812843_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 357.0
HKD1_k127_4812843_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 346.0
HKD1_k127_4812843_3 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 300.0
HKD1_k127_4812843_4 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000000000000000007249 200.0
HKD1_k127_4812843_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000003614 173.0
HKD1_k127_4812843_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000001291 162.0
HKD1_k127_4937868_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 476.0
HKD1_k127_4937868_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 460.0
HKD1_k127_4937868_2 PFAM ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 314.0
HKD1_k127_4937868_3 PFAM peptidase K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 319.0
HKD1_k127_4937868_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 297.0
HKD1_k127_4937868_5 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002032 258.0
HKD1_k127_4937868_6 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000003533 231.0
HKD1_k127_4937868_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000861 196.0
HKD1_k127_4937868_8 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000004136 169.0
HKD1_k127_4937868_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000006925 154.0
HKD1_k127_4952181_0 A predicted alpha-helical domain with a conserved ER motif. - - - 5.144e-222 716.0
HKD1_k127_4952181_1 Putative amidoligase enzyme (DUF2126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 518.0
HKD1_k127_4952181_2 transglutaminase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 313.0
HKD1_k127_4952181_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000003305 87.0
HKD1_k127_499618_0 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 597.0
HKD1_k127_499618_1 Molecular chaperone. Has ATPase activity K04079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 554.0
HKD1_k127_499618_10 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000001024 170.0
HKD1_k127_499618_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000006499 165.0
HKD1_k127_499618_12 RES - - - 0.000000000000000000000000004047 117.0
HKD1_k127_499618_13 protein conserved in bacteria - - - 0.000000000000001211 91.0
HKD1_k127_499618_14 toxin-antitoxin system antitoxin component, TIGR02293 family - - - 0.0000000000000335 82.0
HKD1_k127_499618_15 SnoaL-like polyketide cyclase - - - 0.0001499 54.0
HKD1_k127_499618_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 428.0
HKD1_k127_499618_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 396.0
HKD1_k127_499618_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 379.0
HKD1_k127_499618_5 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 376.0
HKD1_k127_499618_6 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009092 252.0
HKD1_k127_499618_7 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517,K12974 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000003529 231.0
HKD1_k127_499618_8 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000001114 218.0
HKD1_k127_499618_9 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000009708 191.0
HKD1_k127_5015204_0 PFAM PrkA AAA K07180 - - 9.86e-303 943.0
HKD1_k127_5015204_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 6.759e-281 874.0
HKD1_k127_5015204_10 Transcriptional regulator K06714,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 439.0
HKD1_k127_5015204_11 Protein of unknown function (DUF444) K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 411.0
HKD1_k127_5015204_12 DNA repair photolyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 405.0
HKD1_k127_5015204_13 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 391.0
HKD1_k127_5015204_14 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 357.0
HKD1_k127_5015204_15 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000711 283.0
HKD1_k127_5015204_16 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000005265 249.0
HKD1_k127_5015204_17 Two component transcriptional regulator, winged helix family K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000001711 231.0
HKD1_k127_5015204_18 Histidine kinase K02484,K07640,K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001825 241.0
HKD1_k127_5015204_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000003078 190.0
HKD1_k127_5015204_2 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 1.597e-255 823.0
HKD1_k127_5015204_20 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000003901 187.0
HKD1_k127_5015204_21 proteolysis - - - 0.0000000000000000000000000000000000000000000073 174.0
HKD1_k127_5015204_22 Protein of unknown function (DUF3775) - - - 0.00000000000000000000000001275 113.0
HKD1_k127_5015204_23 - - - - 0.000000000000000004603 98.0
HKD1_k127_5015204_24 - - - - 0.00000000000000001178 86.0
HKD1_k127_5015204_25 - - - - 0.000000000004604 74.0
HKD1_k127_5015204_27 - - - - 0.0000006587 62.0
HKD1_k127_5015204_3 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 581.0
HKD1_k127_5015204_4 SpoVR like protein K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 594.0
HKD1_k127_5015204_5 Helicase K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 563.0
HKD1_k127_5015204_6 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 552.0
HKD1_k127_5015204_7 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 516.0
HKD1_k127_5015204_8 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 456.0
HKD1_k127_5015204_9 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 463.0
HKD1_k127_5046337_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 2.696e-217 698.0
HKD1_k127_5046337_1 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 612.0
HKD1_k127_5046337_10 Tetratricopeptide repeat - - - 0.000008785 59.0
HKD1_k127_5046337_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 331.0
HKD1_k127_5046337_3 Serine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 306.0
HKD1_k127_5046337_4 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006772 266.0
HKD1_k127_5046337_5 of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003347 245.0
HKD1_k127_5046337_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001036 251.0
HKD1_k127_5046337_7 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000005877 216.0
HKD1_k127_5046337_8 involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000000000000000000000017 205.0
HKD1_k127_5046337_9 EF-hand domain pair - - - 0.000000000008764 70.0
HKD1_k127_5080343_0 Endothelin-converting enzyme K09610 GO:0003008,GO:0003016,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007218,GO:0007585,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0032501,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 9.814e-217 692.0
HKD1_k127_5080343_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 392.0
HKD1_k127_5080343_10 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000001226 144.0
HKD1_k127_5080343_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000001072 83.0
HKD1_k127_5080343_12 - - - - 0.0000000006211 71.0
HKD1_k127_5080343_13 decarboxylase K01607 - 4.1.1.44 0.000000004451 65.0
HKD1_k127_5080343_2 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 396.0
HKD1_k127_5080343_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 350.0
HKD1_k127_5080343_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
HKD1_k127_5080343_5 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 293.0
HKD1_k127_5080343_6 Transcriptional regulator K18996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001264 274.0
HKD1_k127_5080343_7 peptidase - - - 0.0000000000000000000000000000000000000000000000000005052 193.0
HKD1_k127_5080343_8 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000243 181.0
HKD1_k127_5080343_9 NAD(P)H-dependent FMN reductase - - - 0.00000000000000000000000000000000000000007599 162.0
HKD1_k127_5087189_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.158e-318 1022.0
HKD1_k127_5087189_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.211e-284 888.0
HKD1_k127_5087189_10 Major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 371.0
HKD1_k127_5087189_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 361.0
HKD1_k127_5087189_12 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 364.0
HKD1_k127_5087189_13 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 346.0
HKD1_k127_5087189_14 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 344.0
HKD1_k127_5087189_15 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 298.0
HKD1_k127_5087189_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008211 299.0
HKD1_k127_5087189_17 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006068 297.0
HKD1_k127_5087189_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000107 274.0
HKD1_k127_5087189_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002802 292.0
HKD1_k127_5087189_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.234e-234 737.0
HKD1_k127_5087189_20 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001921 263.0
HKD1_k127_5087189_21 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000001979 247.0
HKD1_k127_5087189_22 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000112 239.0
HKD1_k127_5087189_23 belongs to the bacterial solute-binding protein 3 family K02030,K02424,K10036 - - 0.0000000000000000000000000000000000000000000000000000000000000000332 237.0
HKD1_k127_5087189_24 Transcriptional K03719 - - 0.000000000000000000000000000000000000000000000000000000000000009464 220.0
HKD1_k127_5087189_25 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000001349 215.0
HKD1_k127_5087189_26 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000001657 208.0
HKD1_k127_5087189_27 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000008294 192.0
HKD1_k127_5087189_28 domain protein - - - 0.00000000000000000000000000000000000000000000002696 183.0
HKD1_k127_5087189_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000001105 170.0
HKD1_k127_5087189_3 Aminotransferase class I and II K00812 - 2.6.1.1 5.267e-211 672.0
HKD1_k127_5087189_30 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000002739 181.0
HKD1_k127_5087189_31 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000002443 134.0
HKD1_k127_5087189_32 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000495 126.0
HKD1_k127_5087189_33 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000001543 115.0
HKD1_k127_5087189_34 Protein of unknown function (DUF3237) - - - 0.000000000000000000000702 99.0
HKD1_k127_5087189_35 Belongs to the UPF0311 family - - - 0.0000000000000000005213 87.0
HKD1_k127_5087189_36 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000003399 96.0
HKD1_k127_5087189_37 DsrE/DsrF-like family - - - 0.0000000000000002771 86.0
HKD1_k127_5087189_38 helix_turn_helix multiple antibiotic resistance protein - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000746 85.0
HKD1_k127_5087189_39 PilZ domain - - - 0.00000000000003607 75.0
HKD1_k127_5087189_4 Lytic murein transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 537.0
HKD1_k127_5087189_40 negative regulation of translational initiation - - - 0.00000000000005811 79.0
HKD1_k127_5087189_41 - - - - 0.0000000000003052 73.0
HKD1_k127_5087189_42 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0007154,GO:0007165,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0015688,GO:0015833,GO:0015889,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019062,GO:0019904,GO:0022610,GO:0023052,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0031992,GO:0032991,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0042914,GO:0043213,GO:0044403,GO:0044406,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0044650,GO:0046813,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0051704,GO:0051716,GO:0060089,GO:0065007,GO:0071575,GO:0071702,GO:0071705,GO:0071944,GO:0098002,GO:0098552,GO:0098670,GO:0098796,GO:0098797,GO:1901678 - 0.0000000004416 71.0
HKD1_k127_5087189_43 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000006496 64.0
HKD1_k127_5087189_44 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000007024 71.0
HKD1_k127_5087189_45 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.000000004153 61.0
HKD1_k127_5087189_46 Flagellar biosynthesis type III secretory pathway chaperone K02399 - - 0.00000006332 60.0
HKD1_k127_5087189_47 Flagellar protein K02398 - - 0.0000005779 55.0
HKD1_k127_5087189_48 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000938 62.0
HKD1_k127_5087189_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 500.0
HKD1_k127_5087189_6 transporter K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 475.0
HKD1_k127_5087189_7 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 447.0
HKD1_k127_5087189_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 437.0
HKD1_k127_5087189_9 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 421.0
HKD1_k127_51443_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1103.0
HKD1_k127_51443_1 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 581.0
HKD1_k127_51443_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 493.0
HKD1_k127_5153042_0 Flagellar hook protein FlgE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 486.0
HKD1_k127_5153042_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 473.0
HKD1_k127_5153042_10 Flagellar rod assembly protein muramidase FlgJ K02395 - - 0.00000000000000000000000000000000000000000000000000000006413 207.0
HKD1_k127_5153042_11 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000003253 175.0
HKD1_k127_5153042_12 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000008289 162.0
HKD1_k127_5153042_13 flagellar protein FliS K02422 - - 0.0000000000000000000000000000000002824 135.0
HKD1_k127_5153042_14 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000001277 100.0
HKD1_k127_5153042_15 FlaG protein K06603 - - 0.00000000002752 69.0
HKD1_k127_5153042_16 His Kinase A (phosphoacceptor) domain K10942 - 2.7.13.3 0.0003627 47.0
HKD1_k127_5153042_2 flagellar hook-associated protein K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 449.0
HKD1_k127_5153042_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 391.0
HKD1_k127_5153042_4 basal body rod K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 370.0
HKD1_k127_5153042_5 Fis family transcriptional regulator K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 362.0
HKD1_k127_5153042_6 Belongs to the bacterial flagellin family K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003979 307.0
HKD1_k127_5153042_7 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004671 294.0
HKD1_k127_5153042_8 Belongs to the flagella basal body rod proteins family K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 259.0
HKD1_k127_5153042_9 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000001702 216.0
HKD1_k127_5169884_0 Urate oxidase N-terminal - - - 2.86e-282 905.0
HKD1_k127_5169884_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 580.0
HKD1_k127_5169884_10 DSBA-like thioredoxin domain K07396 - - 0.00000000000000000000000000000000000000000000000000000003189 203.0
HKD1_k127_5169884_11 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000001885 145.0
HKD1_k127_5169884_12 cheY-homologous receiver domain - - - 0.00000000000000000000000006402 109.0
HKD1_k127_5169884_13 Transcriptional regulator - - - 0.00000000000003817 87.0
HKD1_k127_5169884_14 Protein of unknown function (DUF1289) - - - 0.00000000000004463 76.0
HKD1_k127_5169884_15 Planctomycete cytochrome C - - - 0.0000000000004903 80.0
HKD1_k127_5169884_16 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.000000000001714 74.0
HKD1_k127_5169884_17 - - - - 0.00000000005586 67.0
HKD1_k127_5169884_2 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 517.0
HKD1_k127_5169884_3 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 383.0
HKD1_k127_5169884_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 336.0
HKD1_k127_5169884_5 HpcH/HpaI aldolase/citrate lyase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000009187 258.0
HKD1_k127_5169884_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003257 233.0
HKD1_k127_5169884_7 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000005009 222.0
HKD1_k127_5169884_8 PFAM PEBP family protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000001852 215.0
HKD1_k127_5169884_9 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000001501 218.0
HKD1_k127_5173749_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 1.187e-219 697.0
HKD1_k127_5173749_1 COG0277 FAD FMN-containing dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 366.0
HKD1_k127_5173749_2 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000004039 157.0
HKD1_k127_5173749_3 PFAM thioesterase superfamily protein K19222 - 3.1.2.28 0.00000000129 59.0
HKD1_k127_5187959_0 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 521.0
HKD1_k127_5187959_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 445.0
HKD1_k127_5187959_10 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000006365 256.0
HKD1_k127_5187959_11 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006721 255.0
HKD1_k127_5187959_12 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
HKD1_k127_5187959_13 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000009572 238.0
HKD1_k127_5187959_14 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000001605 207.0
HKD1_k127_5187959_15 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000002427 203.0
HKD1_k127_5187959_16 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000002806 170.0
HKD1_k127_5187959_17 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000001427 173.0
HKD1_k127_5187959_18 S1/P1 Nuclease - - - 0.0000000000000000000000000000000003443 150.0
HKD1_k127_5187959_2 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 424.0
HKD1_k127_5187959_3 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 426.0
HKD1_k127_5187959_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
HKD1_k127_5187959_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 382.0
HKD1_k127_5187959_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 376.0
HKD1_k127_5187959_7 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 346.0
HKD1_k127_5187959_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 291.0
HKD1_k127_5187959_9 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 288.0
HKD1_k127_5190206_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1311.0
HKD1_k127_5190206_1 FecR protein - - - 0.00000000000000000000000000000000000000000000000000006871 199.0
HKD1_k127_5190206_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000002961 193.0
HKD1_k127_5205583_0 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 394.0
HKD1_k127_5205583_1 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000001029 229.0
HKD1_k127_5205583_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000003083 192.0
HKD1_k127_5205583_3 Phospholipid N-methyltransferase - - - 0.00000000000000000000000000000000000000126 155.0
HKD1_k127_5205583_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001586 130.0
HKD1_k127_5205583_5 phosphoglycerate mutase - - - 0.00002329 54.0
HKD1_k127_5295596_0 COG4993 Glucose dehydrogenase - - - 1.193e-211 683.0
HKD1_k127_5295596_1 metal-dependent hydrolase of the TIM-barrel fold K03392,K10220 - 4.1.1.45,4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 512.0
HKD1_k127_5295596_10 OmpA family - - - 0.00005465 55.0
HKD1_k127_5295596_2 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 304.0
HKD1_k127_5295596_3 N-acetyltransferase K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000000000000000003183 274.0
HKD1_k127_5295596_4 FAD binding domain K03391,K05712 - 1.14.13.127,1.14.13.50 0.0000000000000000000000000000000000000000000000003992 186.0
HKD1_k127_5295596_5 - - - - 0.000000000000000000000000000000000000000000000001455 190.0
HKD1_k127_5295596_6 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000004387 175.0
HKD1_k127_5295596_7 - - - - 0.000000000000000000002614 108.0
HKD1_k127_5295596_8 - - - - 0.00000000006451 74.0
HKD1_k127_5295596_9 - - - - 0.00000009293 63.0
HKD1_k127_532011_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 586.0
HKD1_k127_532011_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 587.0
HKD1_k127_532011_10 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000007147 190.0
HKD1_k127_532011_11 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000001583 177.0
HKD1_k127_532011_12 - - - - 0.000000000005178 67.0
HKD1_k127_532011_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 552.0
HKD1_k127_532011_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 511.0
HKD1_k127_532011_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 465.0
HKD1_k127_532011_5 cystathione gamma lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 447.0
HKD1_k127_532011_6 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 332.0
HKD1_k127_532011_7 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 269.0
HKD1_k127_532011_8 rRNA processing K06968 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000001946 248.0
HKD1_k127_532011_9 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000000001345 203.0
HKD1_k127_539973_0 Glycosyl transferase family group 2 K03669 GO:0005575,GO:0016020 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 603.0
HKD1_k127_539973_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 585.0
HKD1_k127_539973_12 Protein of unknown function (DUF2845) - - - 0.0007658 47.0
HKD1_k127_539973_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 473.0
HKD1_k127_539973_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 417.0
HKD1_k127_539973_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004781 267.0
HKD1_k127_539973_5 FAD-linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000003459 225.0
HKD1_k127_539973_6 Prolyl 4-hydroxylase alpha subunit homologues. K07336 - - 0.000000000000000000000000000000000000000000000000002169 190.0
HKD1_k127_539973_7 UPF0056 membrane protein - - - 0.000000000000000000000000000000000000000001285 163.0
HKD1_k127_539973_8 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000000000000001024 161.0
HKD1_k127_539973_9 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000001392 154.0
HKD1_k127_5451531_0 ABC transporter K06147,K18893 - - 2.616e-246 776.0
HKD1_k127_5451531_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 514.0
HKD1_k127_5451531_10 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000001551 184.0
HKD1_k127_5451531_11 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000001327 161.0
HKD1_k127_5451531_13 Phosphopantetheine attachment site - - - 0.00000000008938 66.0
HKD1_k127_5451531_2 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 488.0
HKD1_k127_5451531_3 Trypsin-like peptidase domain K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 438.0
HKD1_k127_5451531_4 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 406.0
HKD1_k127_5451531_5 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 392.0
HKD1_k127_5451531_6 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 341.0
HKD1_k127_5451531_7 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 324.0
HKD1_k127_5451531_8 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 303.0
HKD1_k127_5451531_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009178 254.0
HKD1_k127_545452_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1064.0
HKD1_k127_545452_1 Concanavalin A-like lectin/glucanases superfamily - - - 1.356e-252 806.0
HKD1_k127_545452_10 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 442.0
HKD1_k127_545452_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 423.0
HKD1_k127_545452_12 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 417.0
HKD1_k127_545452_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 415.0
HKD1_k127_545452_14 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 397.0
HKD1_k127_545452_15 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 364.0
HKD1_k127_545452_16 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 332.0
HKD1_k127_545452_17 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 324.0
HKD1_k127_545452_18 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 303.0
HKD1_k127_545452_19 ABC-type molybdate transport system, permease component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 304.0
HKD1_k127_545452_2 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 2.455e-247 792.0
HKD1_k127_545452_20 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001459 265.0
HKD1_k127_545452_21 COG3103 SH3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
HKD1_k127_545452_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003501 243.0
HKD1_k127_545452_23 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001265 239.0
HKD1_k127_545452_24 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000138 222.0
HKD1_k127_545452_25 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000000000000000000000432 228.0
HKD1_k127_545452_26 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000002368 190.0
HKD1_k127_545452_27 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000001535 199.0
HKD1_k127_545452_28 Pilin (bacterial filament) K02650,K02655 - - 0.0000000000000000000000000000000000000000001127 166.0
HKD1_k127_545452_29 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000001199 151.0
HKD1_k127_545452_3 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.591e-239 752.0
HKD1_k127_545452_30 Glutathione peroxidase K02199 - - 0.00000000000000000000000000000000000003266 149.0
HKD1_k127_545452_31 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.000000000000000000000000000000000005705 141.0
HKD1_k127_545452_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000002754 103.0
HKD1_k127_545452_34 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000001063 107.0
HKD1_k127_545452_35 Domain of unknown function (DUF4266) - - - 0.00000000000000000001153 100.0
HKD1_k127_545452_36 Ribonuclease 2-5A K01165 GO:0001959,GO:0002252,GO:0002376,GO:0002682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006139,GO:0006355,GO:0006357,GO:0006364,GO:0006396,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009966,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0010646,GO:0010827,GO:0010828,GO:0016070,GO:0016072,GO:0016310,GO:0016363,GO:0016787,GO:0016788,GO:0019219,GO:0019221,GO:0019222,GO:0019538,GO:0019843,GO:0022613,GO:0023051,GO:0023052,GO:0030154,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031974,GO:0031981,GO:0032502,GO:0032879,GO:0034097,GO:0034340,GO:0034399,GO:0034470,GO:0034641,GO:0034660,GO:0034762,GO:0034764,GO:0036211,GO:0042221,GO:0042254,GO:0042802,GO:0043021,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043487,GO:0043488,GO:0043900,GO:0043901,GO:0043903,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045069,GO:0045071,GO:0045087,GO:0045088,GO:0045444,GO:0045893,GO:0045935,GO:0045944,GO:0046324,GO:0046326,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048525,GO:0048583,GO:0048584,GO:0048869,GO:0050776,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060337,GO:0060338,GO:0060759,GO:0061013,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071357,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0098542,GO:0140098,GO:1900076,GO:1900078,GO:1901360,GO:1901363,GO:1901564,GO:1902680,GO:1903311,GO:1903506,GO:1903508,GO:1903900,GO:1903901,GO:2000112,GO:2001141,GO:2001273,GO:2001275 - 0.00000000001257 74.0
HKD1_k127_545452_37 BlaR1 peptidase M56 - - - 0.00002085 55.0
HKD1_k127_545452_38 Tetratricopeptide repeat - - - 0.0000991 54.0
HKD1_k127_545452_4 Glucose / Sorbosone dehydrogenase - - - 2.448e-205 662.0
HKD1_k127_545452_5 - - - - 4.04e-200 640.0
HKD1_k127_545452_6 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 500.0
HKD1_k127_545452_7 PrpF protein K16514 - 5.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 483.0
HKD1_k127_545452_8 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 463.0
HKD1_k127_545452_9 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 432.0
HKD1_k127_548461_0 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 506.0
HKD1_k127_548461_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000001241 218.0
HKD1_k127_548461_2 Cytochrome c - - - 0.000000000000000000000000000002103 132.0
HKD1_k127_548461_3 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.00000115 55.0
HKD1_k127_5529384_0 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 541.0
HKD1_k127_5529384_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 539.0
HKD1_k127_5529384_10 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003129 244.0
HKD1_k127_5529384_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000001047 222.0
HKD1_k127_5529384_12 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000002957 214.0
HKD1_k127_5529384_13 - - - - 0.0000000000000000000000000000000000000001139 166.0
HKD1_k127_5529384_14 Metal-sensitive transcriptional repressor K07807 - - 0.00000000000000000000000000000000000001726 145.0
HKD1_k127_5529384_15 ABC-type antimicrobial peptide transport system, permease component - - - 0.000000000000000000000000000000000001347 147.0
HKD1_k127_5529384_16 - - - - 0.00000000000000000000000004456 112.0
HKD1_k127_5529384_17 - - - - 0.0000000000000000000000004179 108.0
HKD1_k127_5529384_18 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000004059 85.0
HKD1_k127_5529384_19 - - - - 0.0000000000000001314 90.0
HKD1_k127_5529384_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 434.0
HKD1_k127_5529384_20 Tetratricopeptide repeats - - - 0.0000000000000009189 80.0
HKD1_k127_5529384_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 366.0
HKD1_k127_5529384_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 343.0
HKD1_k127_5529384_5 Cytochrome C biogenesis protein transmembrane region K08970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 347.0
HKD1_k127_5529384_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 325.0
HKD1_k127_5529384_7 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 316.0
HKD1_k127_5529384_8 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 314.0
HKD1_k127_5529384_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008737 269.0
HKD1_k127_5569455_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 3.157e-264 829.0
HKD1_k127_5569455_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 4.047e-243 758.0
HKD1_k127_5569455_10 copG family - - - 0.00000000000000001277 84.0
HKD1_k127_5569455_11 Binding-protein-dependent transport system inner membrane component K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000004412 79.0
HKD1_k127_5569455_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.000001025 56.0
HKD1_k127_5569455_2 protein conserved in bacteria - - - 8.609e-226 717.0
HKD1_k127_5569455_3 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 434.0
HKD1_k127_5569455_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 396.0
HKD1_k127_5569455_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 368.0
HKD1_k127_5569455_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 349.0
HKD1_k127_5569455_7 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
HKD1_k127_5569455_8 ATPases associated with a variety of cellular activities K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 320.0
HKD1_k127_5569455_9 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003957 261.0
HKD1_k127_5605636_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1107.0
HKD1_k127_5605636_1 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 6.921e-238 742.0
HKD1_k127_5605636_10 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 410.0
HKD1_k127_5605636_11 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 373.0
HKD1_k127_5605636_12 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 340.0
HKD1_k127_5605636_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 325.0
HKD1_k127_5605636_14 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 332.0
HKD1_k127_5605636_15 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001866 295.0
HKD1_k127_5605636_16 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007896 273.0
HKD1_k127_5605636_17 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 257.0
HKD1_k127_5605636_18 COG1668 ABC-type Na efflux pump, permease component K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002862 271.0
HKD1_k127_5605636_19 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000008003 254.0
HKD1_k127_5605636_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 8.055e-208 658.0
HKD1_k127_5605636_20 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000003532 250.0
HKD1_k127_5605636_21 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000003742 238.0
HKD1_k127_5605636_22 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000003642 224.0
HKD1_k127_5605636_23 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.000000000000000000000000000000000000000000000000000000008859 211.0
HKD1_k127_5605636_24 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000001915 183.0
HKD1_k127_5605636_25 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000001679 144.0
HKD1_k127_5605636_26 Peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000182 147.0
HKD1_k127_5605636_27 RNA-binding - - - 0.0000000000000000000000000000001226 125.0
HKD1_k127_5605636_28 Sulfurtransferase - - - 0.000000000000000000000000005799 116.0
HKD1_k127_5605636_29 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000001353 113.0
HKD1_k127_5605636_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 607.0
HKD1_k127_5605636_30 diguanylate cyclase - - - 0.000000000000000000002579 102.0
HKD1_k127_5605636_31 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000844 98.0
HKD1_k127_5605636_32 Domain of unknown function (DUF4124) - - - 0.000000000000000001931 93.0
HKD1_k127_5605636_33 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000003057 80.0
HKD1_k127_5605636_34 Protein of unknown function (DUF3012) - - - 0.000000000000893 72.0
HKD1_k127_5605636_35 - - - - 0.0000044 55.0
HKD1_k127_5605636_36 alginic acid biosynthetic process K10297 - - 0.00006446 47.0
HKD1_k127_5605636_37 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00008576 51.0
HKD1_k127_5605636_4 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 587.0
HKD1_k127_5605636_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 546.0
HKD1_k127_5605636_6 Bacterial regulatory protein, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 563.0
HKD1_k127_5605636_7 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 476.0
HKD1_k127_5605636_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 449.0
HKD1_k127_5605636_9 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 418.0
HKD1_k127_5636902_0 PFAM Orn DAP Arg decarboxylase 2 K01585 - 4.1.1.19 1.629e-220 702.0
HKD1_k127_5636902_1 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 540.0
HKD1_k127_5636902_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000001391 156.0
HKD1_k127_5636902_11 - - - - 0.0000000000000000000000000000001039 139.0
HKD1_k127_5636902_12 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000003225 117.0
HKD1_k127_5636902_13 Subtilase family - - - 0.0000001149 64.0
HKD1_k127_5636902_2 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 514.0
HKD1_k127_5636902_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 426.0
HKD1_k127_5636902_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 413.0
HKD1_k127_5636902_5 Glutamate-cysteine ligase family 2(GCS2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 406.0
HKD1_k127_5636902_6 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 374.0
HKD1_k127_5636902_7 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 342.0
HKD1_k127_5636902_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 332.0
HKD1_k127_5636902_9 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004567 274.0
HKD1_k127_57061_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 494.0
HKD1_k127_57061_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 492.0
HKD1_k127_57061_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 309.0
HKD1_k127_57061_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002478 299.0
HKD1_k127_57061_4 endonuclease activity - - - 0.0000000000000000000000000000000000000000002414 172.0
HKD1_k127_57061_5 protein conserved in bacteria - - - 0.000000000000000000000000000000009904 136.0
HKD1_k127_57061_6 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.0000000000000000000000000000002374 142.0
HKD1_k127_57061_7 protein conserved in bacteria K15539 - - 0.000000000449 66.0
HKD1_k127_5716121_0 'PFAM Alpha amylase, catalytic K00690 GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.7 1.723e-211 667.0
HKD1_k127_5716121_1 Feruloyl esterase K21105 - 3.1.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 573.0
HKD1_k127_5716121_10 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000001214 165.0
HKD1_k127_5716121_11 Esterase PHB depolymerase - - - 0.00000001376 65.0
HKD1_k127_5716121_2 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 468.0
HKD1_k127_5716121_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 391.0
HKD1_k127_5716121_5 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 352.0
HKD1_k127_5716121_6 periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 352.0
HKD1_k127_5716121_7 Transcriptional regulator sugar kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 312.0
HKD1_k127_5716121_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000004387 221.0
HKD1_k127_5716121_9 Major facilitator superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000426 199.0
HKD1_k127_5895944_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.461e-312 977.0
HKD1_k127_5895944_1 acetolactate synthase K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 8.947e-287 893.0
HKD1_k127_5895944_10 Acetolactate synthase small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000004654 169.0
HKD1_k127_5895944_11 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000486 143.0
HKD1_k127_5895944_2 receptor - - - 5.118e-233 748.0
HKD1_k127_5895944_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 2.762e-196 627.0
HKD1_k127_5895944_4 Aminotransferase class-III K00822,K00833 - 2.6.1.18,2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 550.0
HKD1_k127_5895944_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 533.0
HKD1_k127_5895944_6 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 456.0
HKD1_k127_5895944_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 450.0
HKD1_k127_5895944_8 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 411.0
HKD1_k127_5895944_9 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000001545 229.0
HKD1_k127_592448_0 M61 glycyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 595.0
HKD1_k127_592448_1 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 354.0
HKD1_k127_592448_2 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 343.0
HKD1_k127_592448_3 ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000003096 243.0
HKD1_k127_592448_4 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000002432 221.0
HKD1_k127_592448_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000005181 198.0
HKD1_k127_592448_6 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000001235 190.0
HKD1_k127_592448_7 periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000004566 177.0
HKD1_k127_592448_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000004227 168.0
HKD1_k127_592448_9 - - - - 0.0000000000000000000000001624 121.0
HKD1_k127_5928968_0 AcrB/AcrD/AcrF family - - - 0.0 1279.0
HKD1_k127_5928968_1 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 516.0
HKD1_k127_5928968_10 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000007305 195.0
HKD1_k127_5928968_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000004942 179.0
HKD1_k127_5928968_12 Transporter Component K07112 - - 0.0000000000000000000000000000000000000000004283 171.0
HKD1_k127_5928968_13 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000001005 178.0
HKD1_k127_5928968_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000004341 155.0
HKD1_k127_5928968_15 SnoaL-like domain - - - 0.00000000000000000000000000000000002543 146.0
HKD1_k127_5928968_16 - - - - 0.0000000000000000000000000000000003816 143.0
HKD1_k127_5928968_18 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000001674 119.0
HKD1_k127_5928968_19 Sigma-70 region 2 K03088 - - 0.0000000000000000000000002635 109.0
HKD1_k127_5928968_2 DNA topological change - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 527.0
HKD1_k127_5928968_20 - - - - 0.0000000000000000000000005508 115.0
HKD1_k127_5928968_21 - - - - 0.00000000000000000001694 106.0
HKD1_k127_5928968_22 - K09004 - - 0.000000000000079 81.0
HKD1_k127_5928968_23 - - - - 0.0000000000002741 82.0
HKD1_k127_5928968_24 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000197 57.0
HKD1_k127_5928968_25 Transporter K02429 - - 0.00000294 52.0
HKD1_k127_5928968_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 402.0
HKD1_k127_5928968_4 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 368.0
HKD1_k127_5928968_5 overlaps another CDS with the same product name K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 342.0
HKD1_k127_5928968_6 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
HKD1_k127_5928968_7 Transcriptional regulatory protein, C terminal K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002803 247.0
HKD1_k127_5928968_8 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000004531 213.0
HKD1_k127_5928968_9 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000009902 207.0
HKD1_k127_6084384_0 OmpA family - - - 0.0 1877.0
HKD1_k127_6084384_1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 457.0
HKD1_k127_6084384_2 - - - - 0.000000000000000000000000000000000000000000000000000000002888 217.0
HKD1_k127_6084384_3 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000002376 204.0
HKD1_k127_6084384_4 signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000007822 96.0
HKD1_k127_6084384_5 cyclic nucleotide binding K07003 - - 0.0001219 48.0
HKD1_k127_6101828_0 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 544.0
HKD1_k127_6101828_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 442.0
HKD1_k127_6101828_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 326.0
HKD1_k127_6101828_3 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003113 280.0
HKD1_k127_6101828_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005717 291.0
HKD1_k127_6101828_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000001101 191.0
HKD1_k127_6106457_0 DNA helicase K03654 - 3.6.4.12 5.856e-246 778.0
HKD1_k127_6106457_1 PQQ-like domain K00117 - 1.1.5.2 3.111e-197 635.0
HKD1_k127_6106457_10 - - - - 0.000000007248 62.0
HKD1_k127_6106457_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004604 259.0
HKD1_k127_6106457_3 protein conserved in bacteria K09966 - - 0.0000000000000000000000000000000000000000000000000000000000273 208.0
HKD1_k127_6106457_4 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000001486 209.0
HKD1_k127_6106457_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000008903 117.0
HKD1_k127_6106457_6 - - - - 0.0000000000000009008 88.0
HKD1_k127_6106457_7 Aldo/keto reductase family - - - 0.00000000000001408 74.0
HKD1_k127_6106457_8 - - - - 0.0000000004403 70.0
HKD1_k127_6106457_9 - - - - 0.000000002553 63.0
HKD1_k127_6130842_0 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 358.0
HKD1_k127_6130842_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003383 277.0
HKD1_k127_6130842_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000003813 186.0
HKD1_k127_6130842_3 Multicopper oxidase K04753 - - 0.00000000008871 64.0
HKD1_k127_6163339_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 5.639e-316 1015.0
HKD1_k127_6163339_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 494.0
HKD1_k127_6163339_10 - - - - 0.000000000000004783 87.0
HKD1_k127_6163339_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 265.0
HKD1_k127_6163339_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008839 254.0
HKD1_k127_6163339_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000008475 241.0
HKD1_k127_6163339_5 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
HKD1_k127_6163339_6 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000002113 185.0
HKD1_k127_6163339_7 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000001215 178.0
HKD1_k127_6163339_8 FtsX-like permease family K02004 - - 0.000000000000000000000000000000005166 135.0
HKD1_k127_6163339_9 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000254 124.0
HKD1_k127_6177508_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 373.0
HKD1_k127_6177508_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000007086 235.0
HKD1_k127_6177508_2 Protein of unknown function (DUF423) - - - 0.0000005841 57.0
HKD1_k127_6184914_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 1.164e-198 629.0
HKD1_k127_6184914_1 Uncharacterised MFS-type transporter YbfB K05548,K05819,K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 462.0
HKD1_k127_6184914_10 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000009139 142.0
HKD1_k127_6184914_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000002798 117.0
HKD1_k127_6184914_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 436.0
HKD1_k127_6184914_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 385.0
HKD1_k127_6184914_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 368.0
HKD1_k127_6184914_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
HKD1_k127_6184914_6 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000008117 193.0
HKD1_k127_6184914_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000003038 179.0
HKD1_k127_6184914_8 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000001134 184.0
HKD1_k127_6184914_9 Predicted membrane protein (DUF2214) - - - 0.0000000000000000000000000000000000000002461 153.0
HKD1_k127_6206120_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 8.409e-222 707.0
HKD1_k127_6206120_1 PQQ enzyme repeat K00117 - 1.1.5.2 3.996e-194 627.0
HKD1_k127_6206120_10 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 300.0
HKD1_k127_6206120_11 FAD linked K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 281.0
HKD1_k127_6206120_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001206 269.0
HKD1_k127_6206120_13 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002119 263.0
HKD1_k127_6206120_14 Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000000000000000000000002081 183.0
HKD1_k127_6206120_15 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000001654 176.0
HKD1_k127_6206120_16 - - - - 0.0000000000000000000000000000000000000007991 162.0
HKD1_k127_6206120_17 FMN-binding domain protein - - - 0.000000000000000000000000000000000000009842 160.0
HKD1_k127_6206120_18 - - - - 0.0000000000000000000000000000000000003104 159.0
HKD1_k127_6206120_19 - - - - 0.0000000000000000000000000000000000005923 144.0
HKD1_k127_6206120_2 PQQ-like domain K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 595.0
HKD1_k127_6206120_20 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000005567 140.0
HKD1_k127_6206120_21 Putative phage abortive infection protein - - - 0.000000000000000000000000000000001889 141.0
HKD1_k127_6206120_22 - - - - 0.000000000000000000000000000000002341 136.0
HKD1_k127_6206120_23 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000002194 121.0
HKD1_k127_6206120_24 YfaZ precursor - - - 0.00000000003137 71.0
HKD1_k127_6206120_25 - - - - 0.0000000002016 73.0
HKD1_k127_6206120_3 4Fe-4S dicluster domain K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 522.0
HKD1_k127_6206120_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 430.0
HKD1_k127_6206120_5 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 425.0
HKD1_k127_6206120_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 402.0
HKD1_k127_6206120_7 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 391.0
HKD1_k127_6206120_8 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 374.0
HKD1_k127_6206120_9 Dihydroxyacetone kinase K00863 - 2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 350.0
HKD1_k127_6239759_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 1.446e-267 843.0
HKD1_k127_6239759_1 PQQ-like domain K00117 - 1.1.5.2 7.764e-214 683.0
HKD1_k127_6239759_10 Bacterial virulence protein (VirJ) - - - 0.0009541 50.0
HKD1_k127_6239759_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 529.0
HKD1_k127_6239759_3 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 441.0
HKD1_k127_6239759_4 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 323.0
HKD1_k127_6239759_5 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 312.0
HKD1_k127_6239759_6 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000001325 209.0
HKD1_k127_6239759_7 GabA permease K11735 - - 0.000000000000000000000000000000000001616 142.0
HKD1_k127_6239759_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000002572 126.0
HKD1_k127_6239759_9 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.0000000000000000000003145 113.0
HKD1_k127_6259427_0 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 539.0
HKD1_k127_6259427_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000003436 238.0
HKD1_k127_6259427_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000001752 85.0
HKD1_k127_6300945_0 acyl-CoA dehydrogenase K00252 - 1.3.8.6 7.283e-206 655.0
HKD1_k127_6300945_1 FAD linked oxidase domain protein K05797 - 1.17.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 561.0
HKD1_k127_6300945_10 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000008969 188.0
HKD1_k127_6300945_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001537 173.0
HKD1_k127_6300945_12 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family - - - 0.00000000000000000000000000000000000000006604 155.0
HKD1_k127_6300945_13 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000165 146.0
HKD1_k127_6300945_14 HNH nucleases - - - 0.000000000000000000000000000000000004077 145.0
HKD1_k127_6300945_15 - - - - 0.000000000000000000004756 107.0
HKD1_k127_6300945_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000004421 96.0
HKD1_k127_6300945_17 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000004851 63.0
HKD1_k127_6300945_18 - - - - 0.00001395 55.0
HKD1_k127_6300945_19 - - - - 0.00004065 56.0
HKD1_k127_6300945_2 regulation of methylation-dependent chromatin silencing K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 399.0
HKD1_k127_6300945_3 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 403.0
HKD1_k127_6300945_4 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 385.0
HKD1_k127_6300945_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 313.0
HKD1_k127_6300945_6 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 316.0
HKD1_k127_6300945_8 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000008187 237.0
HKD1_k127_6300945_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000004277 226.0
HKD1_k127_6331399_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.96e-282 876.0
HKD1_k127_6331399_1 Helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 574.0
HKD1_k127_6331399_10 TIGRFAM conserved repeat domain - - - 0.00000000000000004469 91.0
HKD1_k127_6331399_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 453.0
HKD1_k127_6331399_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 428.0
HKD1_k127_6331399_4 Belongs to the transferase hexapeptide repeat family K00674 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 365.0
HKD1_k127_6331399_5 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 344.0
HKD1_k127_6331399_6 Two component response regulator for the phosphate regulon K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 301.0
HKD1_k127_6331399_7 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
HKD1_k127_6331399_8 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000002104 166.0
HKD1_k127_6331399_9 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000001373 163.0
HKD1_k127_6354529_0 Required for chromosome condensation and partitioning K03529 - - 1.604e-309 987.0
HKD1_k127_6354529_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003824,GO:0004654,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.8 1.073e-303 945.0
HKD1_k127_6354529_10 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 383.0
HKD1_k127_6354529_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 301.0
HKD1_k127_6354529_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 290.0
HKD1_k127_6354529_13 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001932 284.0
HKD1_k127_6354529_14 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000001373 240.0
HKD1_k127_6354529_15 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000007544 219.0
HKD1_k127_6354529_16 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000000000001229 195.0
HKD1_k127_6354529_17 - - - - 0.0000000000000000000000000000000000000000000000000001348 190.0
HKD1_k127_6354529_18 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000006152 195.0
HKD1_k127_6354529_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000701 205.0
HKD1_k127_6354529_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.664e-293 922.0
HKD1_k127_6354529_20 heme binding K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000002101 190.0
HKD1_k127_6354529_21 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000003246 187.0
HKD1_k127_6354529_22 - - - - 0.00000000000000000000000000000000000000000000002603 184.0
HKD1_k127_6354529_23 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000001378 159.0
HKD1_k127_6354529_24 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000003189 133.0
HKD1_k127_6354529_25 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000003818 138.0
HKD1_k127_6354529_26 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000001042 142.0
HKD1_k127_6354529_27 - - - - 0.0000000000000000000000001083 122.0
HKD1_k127_6354529_28 - - - - 0.0000000000000000000009478 109.0
HKD1_k127_6354529_29 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000002686 94.0
HKD1_k127_6354529_3 PQQ enzyme repeat K00114 - 1.1.2.8 4.264e-240 765.0
HKD1_k127_6354529_30 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000001261 65.0
HKD1_k127_6354529_31 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.00000000006247 71.0
HKD1_k127_6354529_32 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0004367 49.0
HKD1_k127_6354529_4 Participates in both transcription termination and antitermination K02600 - - 5.195e-218 687.0
HKD1_k127_6354529_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 548.0
HKD1_k127_6354529_6 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 471.0
HKD1_k127_6354529_7 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 469.0
HKD1_k127_6354529_8 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 426.0
HKD1_k127_6354529_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 409.0
HKD1_k127_638253_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1187.0
HKD1_k127_638253_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 521.0
HKD1_k127_638253_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000055 292.0
HKD1_k127_638253_3 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 268.0
HKD1_k127_638253_4 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000005247 237.0
HKD1_k127_638253_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000004988 130.0
HKD1_k127_648228_0 Protein involved in UDP-N-acetylmuramate dehydrogenase activity and amino sugar metabolic process K05797 - 1.17.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 600.0
HKD1_k127_648228_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 587.0
HKD1_k127_648228_2 HflC and HflK could encode or regulate a protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 391.0
HKD1_k127_648228_3 prohibitin homologues K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 396.0
HKD1_k127_648228_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 373.0
HKD1_k127_648228_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002572 238.0
HKD1_k127_648228_6 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000003246 181.0
HKD1_k127_648228_7 - - - - 0.00000000001427 76.0
HKD1_k127_648228_8 - - - - 0.00000002514 65.0
HKD1_k127_6482538_0 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 338.0
HKD1_k127_6482538_1 Prolyl oligopeptidase - - - 0.000000000000006586 89.0
HKD1_k127_6482538_2 (ABC) transporter K06147,K06148 - - 0.00000000000319 66.0
HKD1_k127_6482935_0 Dehydrogenase K00117 - 1.1.5.2 2.535e-275 862.0
HKD1_k127_6482935_1 Luciferase-like monooxygenase - - - 5.033e-195 612.0
HKD1_k127_6482935_10 Histidine kinase K01120,K07315 - 3.1.3.3,3.1.4.17 0.0000000000000000000000000000000000000000000001743 189.0
HKD1_k127_6482935_11 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000001001 132.0
HKD1_k127_6482935_12 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000005068 126.0
HKD1_k127_6482935_13 Alpha beta hydrolase fold-3 domain protein - - - 0.00000000000000000000000000005186 121.0
HKD1_k127_6482935_14 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000003423 119.0
HKD1_k127_6482935_15 - - - - 0.0000000001076 70.0
HKD1_k127_6482935_16 Thioesterase domain - - - 0.00000002085 59.0
HKD1_k127_6482935_17 - - - - 0.0000005199 62.0
HKD1_k127_6482935_18 Glyoxalase-like domain - - - 0.000006271 58.0
HKD1_k127_6482935_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 451.0
HKD1_k127_6482935_3 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 373.0
HKD1_k127_6482935_4 receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 381.0
HKD1_k127_6482935_5 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 340.0
HKD1_k127_6482935_6 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 338.0
HKD1_k127_6482935_7 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005079 255.0
HKD1_k127_6482935_8 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000002735 235.0
HKD1_k127_6482935_9 NUDIX domain - - - 0.00000000000000000000000000000000000000000000009507 173.0
HKD1_k127_6504355_0 domain protein - - - 6.816e-307 987.0
HKD1_k127_6504355_1 Tetratricopeptide repeat - - - 2.692e-205 658.0
HKD1_k127_6504355_10 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000005215 128.0
HKD1_k127_6504355_11 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000199 126.0
HKD1_k127_6504355_12 - - - - 0.0000000000000002008 85.0
HKD1_k127_6504355_2 Tetratricopeptide repeat - - - 4.68e-203 651.0
HKD1_k127_6504355_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 575.0
HKD1_k127_6504355_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 365.0
HKD1_k127_6504355_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 344.0
HKD1_k127_6504355_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009976 274.0
HKD1_k127_6504355_7 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000005613 235.0
HKD1_k127_6504355_8 - - - - 0.00000000000000000000000000000000000000000000004732 176.0
HKD1_k127_6504355_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000003581 163.0
HKD1_k127_653715_0 Aminotransferase class-III K01845 - 5.4.3.8 3.479e-244 766.0
HKD1_k127_653715_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 346.0
HKD1_k127_653715_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 293.0
HKD1_k127_653715_3 Phospholipid N-methyltransferase - - - 0.000000000000000000000000000000000000003137 159.0
HKD1_k127_6602117_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 552.0
HKD1_k127_6602117_1 Retinal pigment epithelial membrane protein K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 378.0
HKD1_k127_6602117_2 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 345.0
HKD1_k127_6602117_3 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001052 292.0
HKD1_k127_6602117_6 histone H4-K16 acetylation K07020 - - 0.0000000000000000000000000000000000000000005447 179.0
HKD1_k127_6602117_7 - - - - 0.00000000000009793 76.0
HKD1_k127_6602117_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000007168 58.0
HKD1_k127_6698831_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.019e-280 869.0
HKD1_k127_6698831_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 458.0
HKD1_k127_6698831_10 Protein of unknown function (DUF2909) - - - 0.000009178 50.0
HKD1_k127_6698831_2 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 390.0
HKD1_k127_6698831_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 362.0
HKD1_k127_6698831_4 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 335.0
HKD1_k127_6698831_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 318.0
HKD1_k127_6698831_6 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.00000000000000000000000000000000000000000000008597 173.0
HKD1_k127_6698831_7 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000006403 132.0
HKD1_k127_6698831_8 SURF1-like protein K14998 - - 0.00000000000000000000000000002218 128.0
HKD1_k127_6698831_9 signal sequence binding - - - 0.00000003619 64.0
HKD1_k127_67353_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1144.0
HKD1_k127_67353_1 Dehydratase family K13875 - 4.2.1.25 2.975e-304 940.0
HKD1_k127_67353_10 Converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 456.0
HKD1_k127_67353_11 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 446.0
HKD1_k127_67353_12 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 443.0
HKD1_k127_67353_13 PFAM ABC transporter related K10554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 421.0
HKD1_k127_67353_14 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 399.0
HKD1_k127_67353_15 Galactose 1-dehydrogenase K00035 - 1.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 386.0
HKD1_k127_67353_16 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 366.0
HKD1_k127_67353_17 Transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 343.0
HKD1_k127_67353_18 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 349.0
HKD1_k127_67353_19 Gluconolactonase K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 335.0
HKD1_k127_67353_2 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 5.506e-214 683.0
HKD1_k127_67353_20 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 323.0
HKD1_k127_67353_21 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 306.0
HKD1_k127_67353_22 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 315.0
HKD1_k127_67353_23 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 309.0
HKD1_k127_67353_24 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 303.0
HKD1_k127_67353_25 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 289.0
HKD1_k127_67353_26 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004516 289.0
HKD1_k127_67353_27 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007211 260.0
HKD1_k127_67353_28 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000009017 243.0
HKD1_k127_67353_29 peroxidase activity K00435 - - 0.000000000000000000000000000000000000000000000000000000000000000000001301 260.0
HKD1_k127_67353_3 COG1012 NAD-dependent aldehyde dehydrogenases K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 599.0
HKD1_k127_67353_30 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000002389 206.0
HKD1_k127_67353_31 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000189 167.0
HKD1_k127_67353_32 signal transduction histidine kinase - - - 0.00000000000000000000000000000000001355 153.0
HKD1_k127_67353_33 SnoaL-like domain - - - 0.00000000000000000000000000000002312 140.0
HKD1_k127_67353_34 Regulatory protein recX K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.00000000000000000000000000004438 126.0
HKD1_k127_67353_35 - - - - 0.0000000000000000000000003062 115.0
HKD1_k127_67353_36 phospholipase Carboxylesterase - - - 0.000000000000000000000001909 110.0
HKD1_k127_67353_37 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000000002015 98.0
HKD1_k127_67353_38 SnoaL-like domain - - - 0.00000000006032 74.0
HKD1_k127_67353_39 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000001106 56.0
HKD1_k127_67353_4 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 521.0
HKD1_k127_67353_40 phospholipase Carboxylesterase - - - 0.0002804 50.0
HKD1_k127_67353_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 519.0
HKD1_k127_67353_6 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 527.0
HKD1_k127_67353_7 Dihydrodipicolinate synthetase family K13876 - 4.2.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 490.0
HKD1_k127_67353_8 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 498.0
HKD1_k127_67353_9 Belongs to the binding-protein-dependent transport system permease family K10553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 462.0
HKD1_k127_6739397_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.608e-252 788.0
HKD1_k127_6739397_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 584.0
HKD1_k127_6739397_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000764 262.0
HKD1_k127_6739397_3 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
HKD1_k127_6739397_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000000000002345 83.0
HKD1_k127_6739397_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000002326 51.0
HKD1_k127_674409_0 negative regulation of hippo signaling - - - 1.027e-230 746.0
HKD1_k127_674409_1 Protein of unknown function, DUF255 K06888 - - 1.144e-223 713.0
HKD1_k127_674409_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 440.0
HKD1_k127_674409_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 333.0
HKD1_k127_674409_4 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 315.0
HKD1_k127_674409_5 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
HKD1_k127_674409_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000471 226.0
HKD1_k127_674409_7 - - - - 0.00000000000000000000000003022 113.0
HKD1_k127_674409_8 - - - - 0.00000000000000006739 81.0
HKD1_k127_674409_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000000000000008566 81.0
HKD1_k127_6757196_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 414.0
HKD1_k127_6757196_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 406.0
HKD1_k127_6757196_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000003354 168.0
HKD1_k127_6757196_11 methyltransferase - - - 0.00000000000000000000000000000000000000001498 168.0
HKD1_k127_6757196_12 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000000000000000000000000000000004934 161.0
HKD1_k127_6757196_13 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000529 143.0
HKD1_k127_6757196_14 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001057 137.0
HKD1_k127_6757196_15 GntR family transcriptional regulator K07979 - - 0.000000000000000000000000000002501 124.0
HKD1_k127_6757196_16 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.00000000000000000000000000000583 126.0
HKD1_k127_6757196_17 AntiSigma factor - - - 0.00000000000002635 82.0
HKD1_k127_6757196_18 COG0457 FOG TPR repeat - - - 0.00000000002795 76.0
HKD1_k127_6757196_19 - - - - 0.000007465 55.0
HKD1_k127_6757196_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 333.0
HKD1_k127_6757196_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 322.0
HKD1_k127_6757196_4 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 315.0
HKD1_k127_6757196_5 bacteriocin export ABC transporter, lactococcin 972 group K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 293.0
HKD1_k127_6757196_6 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000005146 247.0
HKD1_k127_6757196_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000002511 231.0
HKD1_k127_6757196_8 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000002243 195.0
HKD1_k127_6757196_9 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000001654 170.0
HKD1_k127_6774281_0 - - - - 1.832e-292 918.0
HKD1_k127_6774281_1 Belongs to the ABC transporter superfamily K02031,K02032 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 5.136e-282 906.0
HKD1_k127_6774281_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001239 282.0
HKD1_k127_6774281_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001789 303.0
HKD1_k127_6774281_12 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 253.0
HKD1_k127_6774281_13 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000003762 222.0
HKD1_k127_6774281_14 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000008704 194.0
HKD1_k127_6774281_15 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000407 187.0
HKD1_k127_6774281_16 - - - - 0.000000000000000000000000000000000000000000001106 182.0
HKD1_k127_6774281_17 FAD linked oxidases, C-terminal domain K18930 - - 0.000000000000000000000000000000000000000002105 157.0
HKD1_k127_6774281_18 DNA-templated transcription, initiation K03088,K03091 - - 0.00000000000000000000000000000000000000003342 159.0
HKD1_k127_6774281_19 cellulase activity - - - 0.00000000000000000000000000000000000001837 157.0
HKD1_k127_6774281_2 Peptidase family M49 K01277 - 3.4.14.4 1.863e-242 770.0
HKD1_k127_6774281_20 - - - - 0.0000000000000000000000000000001113 129.0
HKD1_k127_6774281_21 - - - - 0.0000000000000000000000000009515 118.0
HKD1_k127_6774281_22 - - - - 0.000000000000000000000000003214 121.0
HKD1_k127_6774281_23 - - - - 0.00000000000000001461 94.0
HKD1_k127_6774281_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 548.0
HKD1_k127_6774281_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 526.0
HKD1_k127_6774281_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 381.0
HKD1_k127_6774281_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 373.0
HKD1_k127_6774281_7 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 364.0
HKD1_k127_6774281_8 Carboxypeptidase regulatory-like domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 340.0
HKD1_k127_6774281_9 Membrane-associated sensor, integral membrane domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 307.0
HKD1_k127_6795773_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 618.0
HKD1_k127_6795773_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 492.0
HKD1_k127_6795773_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000006228 114.0
HKD1_k127_6795773_11 COG3312 F0F1-type ATP synthase, subunit I K02116 - - 0.000001671 55.0
HKD1_k127_6795773_2 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 368.0
HKD1_k127_6795773_3 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 351.0
HKD1_k127_6795773_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 312.0
HKD1_k127_6795773_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 300.0
HKD1_k127_6795773_6 cytochrome - - - 0.000000000000000000000000000000000000000001584 164.0
HKD1_k127_6795773_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000001609 161.0
HKD1_k127_6795773_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000014 155.0
HKD1_k127_6795773_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000006104 146.0
HKD1_k127_6807888_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 470.0
HKD1_k127_6807888_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 409.0
HKD1_k127_6807888_10 MgtE intracellular N domain - - - 0.000000000000000000000001033 120.0
HKD1_k127_6807888_12 KR domain - - - 0.000002231 52.0
HKD1_k127_6807888_13 Conserved TM helix - - - 0.0003099 52.0
HKD1_k127_6807888_2 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 401.0
HKD1_k127_6807888_3 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 370.0
HKD1_k127_6807888_4 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 334.0
HKD1_k127_6807888_5 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004342 252.0
HKD1_k127_6807888_6 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001711 231.0
HKD1_k127_6807888_7 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000155 197.0
HKD1_k127_6807888_8 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000000000000000004091 154.0
HKD1_k127_6807888_9 AsmA family K07289 - - 0.000000000000000000000000000000008337 139.0
HKD1_k127_6844913_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K21133 - - 0.0 1081.0
HKD1_k127_6844913_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.45e-241 748.0
HKD1_k127_6844913_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 2.14e-199 628.0
HKD1_k127_6844913_3 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 411.0
HKD1_k127_6844913_4 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005576 260.0
HKD1_k127_6844913_5 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001065 265.0
HKD1_k127_6844913_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000003219 250.0
HKD1_k127_6861006_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.925e-265 823.0
HKD1_k127_6861006_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.164e-230 720.0
HKD1_k127_6861006_10 Thioredoxin-like - - - 0.000000000000000000000000001915 119.0
HKD1_k127_6861006_11 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000000001162 104.0
HKD1_k127_6861006_12 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.0000000000000000001446 92.0
HKD1_k127_6861006_13 Protein of unknown function (DUF3426) - - - 0.0000000000000001024 92.0
HKD1_k127_6861006_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.435e-194 635.0
HKD1_k127_6861006_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 603.0
HKD1_k127_6861006_4 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 550.0
HKD1_k127_6861006_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 373.0
HKD1_k127_6861006_6 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000008026 244.0
HKD1_k127_6861006_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000003788 189.0
HKD1_k127_6861006_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000006409 167.0
HKD1_k127_6861006_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000009658 171.0
HKD1_k127_6920965_0 DNA polymerase type-B family K02336 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000004824 273.0
HKD1_k127_6920965_1 NHL repeat - - - 0.00000000000000000000000000000000000000000001581 179.0
HKD1_k127_6920965_3 Phospholipid methyltransferase - - - 0.000000000000000000001981 107.0
HKD1_k127_6920965_4 - - - - 0.000000001097 59.0
HKD1_k127_7082527_0 TonB-dependent receptor plug K02014 - - 9.124e-227 724.0
HKD1_k127_7082527_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.426e-224 713.0
HKD1_k127_7082527_11 Sulfotransferase domain - - - 0.0000005486 57.0
HKD1_k127_7082527_2 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 450.0
HKD1_k127_7082527_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 297.0
HKD1_k127_7082527_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 306.0
HKD1_k127_7082527_5 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006137 269.0
HKD1_k127_7082527_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001524 262.0
HKD1_k127_7082527_7 TPM domain - - - 0.0000000000000000000000000000000000000005721 166.0
HKD1_k127_7082527_8 - - - - 0.00000000000000000000000001832 121.0
HKD1_k127_7082527_9 SNARE associated Golgi protein - - - 0.00000000000000000000001608 116.0
HKD1_k127_7083442_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1238.0
HKD1_k127_7083442_1 receptor K02014 - - 1.058e-315 985.0
HKD1_k127_7083442_10 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001568 283.0
HKD1_k127_7083442_11 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006952 278.0
HKD1_k127_7083442_12 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003968 273.0
HKD1_k127_7083442_13 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004568 271.0
HKD1_k127_7083442_14 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000001178 246.0
HKD1_k127_7083442_15 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000002426 245.0
HKD1_k127_7083442_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000003458 229.0
HKD1_k127_7083442_17 MerR, DNA binding K13639 - - 0.000000000000000000000000000000000000000000000000000000003405 203.0
HKD1_k127_7083442_18 PFAM branched-chain amino acid transport - - - 0.0000000000000000000000000000000001244 145.0
HKD1_k127_7083442_19 transcriptional - - - 0.0000000000000000000000000009097 116.0
HKD1_k127_7083442_2 COG4993 Glucose dehydrogenase - - - 2.455e-215 685.0
HKD1_k127_7083442_20 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000449 119.0
HKD1_k127_7083442_21 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000234 106.0
HKD1_k127_7083442_22 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000001245 103.0
HKD1_k127_7083442_23 CHRD domain containing protein - - - 0.00001029 55.0
HKD1_k127_7083442_3 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 1.175e-203 654.0
HKD1_k127_7083442_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 3.217e-200 631.0
HKD1_k127_7083442_5 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 554.0
HKD1_k127_7083442_6 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 433.0
HKD1_k127_7083442_7 FAD-NAD(P)-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 435.0
HKD1_k127_7083442_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 364.0
HKD1_k127_7083442_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008156 287.0
HKD1_k127_7095587_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 1.03e-261 828.0
HKD1_k127_7095587_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.117e-201 642.0
HKD1_k127_7095587_10 PDZ domain - - - 0.0000000000000007474 89.0
HKD1_k127_7095587_2 recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 386.0
HKD1_k127_7095587_3 Membrane protein TerC, possibly involved in tellurium resistance - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 307.0
HKD1_k127_7095587_4 carbonate dehydratase activity K01674 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002877 287.0
HKD1_k127_7095587_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000004003 216.0
HKD1_k127_7095587_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000002849 160.0
HKD1_k127_7095587_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000004913 149.0
HKD1_k127_7095587_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000001431 132.0
HKD1_k127_7095587_9 DoxX K15977 - - 0.000000000000000000000002249 112.0
HKD1_k127_7110866_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 566.0
HKD1_k127_7110866_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 411.0
HKD1_k127_7110866_2 transporter, permease K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 409.0
HKD1_k127_7110866_3 Oligopeptide transport system permease protein K15582 - - 0.000000000000002039 89.0
HKD1_k127_7126417_0 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 468.0
HKD1_k127_7126417_1 Aspartate tyrosine aromatic aminotransferase K00813,K00832 - 2.6.1.1,2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 436.0
HKD1_k127_7126417_3 NADPH:quinone reductase activity K00344 GO:0000166,GO:0003674,GO:0003824,GO:0003960,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0010941,GO:0016491,GO:0016651,GO:0016655,GO:0019362,GO:0019637,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0042981,GO:0043067,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0048038,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0051186,GO:0055086,GO:0055114,GO:0065007,GO:0070402,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 373.0
HKD1_k127_7126417_4 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
HKD1_k127_7126417_5 regulation of cobalamin metabolic process K11390 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401 - 0.000000000000000000000000000000000000000000000000000000000000000000001142 250.0
HKD1_k127_7126417_6 - - - - 0.0000000000000003512 84.0
HKD1_k127_7161729_0 PUA-like domain K00958 - 2.7.7.4 1.177e-275 857.0
HKD1_k127_7161729_1 Sulfite reductase K00381 - 1.8.1.2 2.401e-233 736.0
HKD1_k127_7161729_10 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 368.0
HKD1_k127_7161729_11 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 368.0
HKD1_k127_7161729_12 malonyl CoA-acyl carrier protein transacylase K00645,K13935 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 323.0
HKD1_k127_7161729_13 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 309.0
HKD1_k127_7161729_14 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001538 295.0
HKD1_k127_7161729_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002334 268.0
HKD1_k127_7161729_16 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000239 252.0
HKD1_k127_7161729_17 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000005942 247.0
HKD1_k127_7161729_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000001883 234.0
HKD1_k127_7161729_19 protein conserved in bacteria K09958 - - 0.0000000000000000000000000000000000000000000000000000000000004633 219.0
HKD1_k127_7161729_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 583.0
HKD1_k127_7161729_20 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000003162 208.0
HKD1_k127_7161729_21 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000001128 188.0
HKD1_k127_7161729_22 Bacterial protein of unknown function (DUF934) - - - 0.00000000000000000000000000000000000000000000001353 194.0
HKD1_k127_7161729_23 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000005019 174.0
HKD1_k127_7161729_24 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000001126 183.0
HKD1_k127_7161729_25 Putative membrane peptidase family (DUF2324) - - - 0.00000000000000000000000000000000002125 145.0
HKD1_k127_7161729_26 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000001542 134.0
HKD1_k127_7161729_27 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000007629 106.0
HKD1_k127_7161729_28 Protein of unknown function (DUF2849) - - - 0.000000000004965 74.0
HKD1_k127_7161729_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 539.0
HKD1_k127_7161729_30 - - - - 0.00000000004201 71.0
HKD1_k127_7161729_31 protein conserved in bacteria - - - 0.0006973 45.0
HKD1_k127_7161729_4 MFS/sugar transport protein K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 520.0
HKD1_k127_7161729_5 phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 504.0
HKD1_k127_7161729_6 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 447.0
HKD1_k127_7161729_7 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 376.0
HKD1_k127_7161729_8 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 377.0
HKD1_k127_7161729_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 377.0
HKD1_k127_7171948_0 DNA topological change K03168 - 5.99.1.2 4.334e-200 651.0
HKD1_k127_7171948_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 365.0
HKD1_k127_7171948_10 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000000007833 191.0
HKD1_k127_7171948_11 acetyltransferase - - - 0.0000000000000000000000000000000000000000002268 179.0
HKD1_k127_7171948_12 Ankyrin repeat and KH K16726 GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0009605,GO:0009607,GO:0009653,GO:0009887,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0010639,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0016043,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0040011,GO:0042692,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044085,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045087,GO:0045214,GO:0046530,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051146,GO:0051704,GO:0051707,GO:0051716,GO:0055001,GO:0055002,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071840,GO:0090596,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:1903146,GO:1903147 - 0.000000000000000002936 97.0
HKD1_k127_7171948_2 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 357.0
HKD1_k127_7171948_3 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 341.0
HKD1_k127_7171948_4 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 337.0
HKD1_k127_7171948_5 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 288.0
HKD1_k127_7171948_6 ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001346 279.0
HKD1_k127_7171948_7 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 286.0
HKD1_k127_7171948_8 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 267.0
HKD1_k127_7171948_9 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000000001699 214.0
HKD1_k127_7207477_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.804e-284 894.0
HKD1_k127_7207477_1 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 4.61e-278 921.0
HKD1_k127_7207477_10 adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000001073 219.0
HKD1_k127_7207477_11 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000007436 214.0
HKD1_k127_7207477_12 - - - - 0.00000000000000000000000000000000000000000000000000000000002828 216.0
HKD1_k127_7207477_13 Iron-sulfur cluster insertion protein ErpA K15724 - - 0.00000000000000000000000000000000000000000000000005053 179.0
HKD1_k127_7207477_14 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000001152 182.0
HKD1_k127_7207477_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000001634 179.0
HKD1_k127_7207477_16 cell shape determination - - - 0.000000000000000000000000000001864 125.0
HKD1_k127_7207477_17 - - - - 0.000000000000000000000002796 102.0
HKD1_k127_7207477_18 Two component signalling adaptor domain K06598 - - 0.00000000000000000001244 98.0
HKD1_k127_7207477_19 - - - - 0.00000000000000001249 91.0
HKD1_k127_7207477_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 496.0
HKD1_k127_7207477_3 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 422.0
HKD1_k127_7207477_4 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 381.0
HKD1_k127_7207477_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 369.0
HKD1_k127_7207477_6 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 340.0
HKD1_k127_7207477_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 356.0
HKD1_k127_7207477_8 chemotaxis, protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 325.0
HKD1_k127_7207477_9 PFAM N-acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000009364 241.0
HKD1_k127_7215886_0 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000002859 168.0
HKD1_k127_7215886_1 - - - - 0.000000000000000001305 90.0
HKD1_k127_7215886_2 - - - - 0.0000000000000003788 89.0
HKD1_k127_7215886_3 Putative esterase - - - 0.000000007043 57.0
HKD1_k127_7215886_4 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000005926 65.0
HKD1_k127_7228166_0 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 580.0
HKD1_k127_7228166_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 366.0
HKD1_k127_7228166_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 349.0
HKD1_k127_7228166_3 aldo keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 338.0
HKD1_k127_7228166_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005217 258.0
HKD1_k127_7228166_5 Cupin domain - - - 0.000000000000000000000000000000002955 137.0
HKD1_k127_7228166_6 - - - - 0.0000000000000000000002725 100.0
HKD1_k127_7228166_7 - - - - 0.00000000003309 74.0
HKD1_k127_7263538_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1182.0
HKD1_k127_7263538_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1153.0
HKD1_k127_7263538_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 394.0
HKD1_k127_7263538_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 360.0
HKD1_k127_7263538_12 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 374.0
HKD1_k127_7263538_13 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 354.0
HKD1_k127_7263538_14 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
HKD1_k127_7263538_15 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000511 278.0
HKD1_k127_7263538_16 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000001035 258.0
HKD1_k127_7263538_17 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000002528 217.0
HKD1_k127_7263538_18 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000007387 209.0
HKD1_k127_7263538_19 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000005695 208.0
HKD1_k127_7263538_2 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 5.975e-237 745.0
HKD1_k127_7263538_20 Pilin (bacterial filament) K02650,K02655 - - 0.00000000000000000000000000000000000000000000000000379 186.0
HKD1_k127_7263538_21 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000189 186.0
HKD1_k127_7263538_22 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000009841 134.0
HKD1_k127_7263538_23 Regulatory protein, FmdB family - - - 0.00000000000000000000000000009296 119.0
HKD1_k127_7263538_24 Pilin (bacterial filament) K02650,K02655 - - 0.0000000000000000001109 96.0
HKD1_k127_7263538_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 618.0
HKD1_k127_7263538_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 510.0
HKD1_k127_7263538_5 PFAM response regulator receiver K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000836 537.0
HKD1_k127_7263538_6 Type II secretory pathway, component PulF K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 505.0
HKD1_k127_7263538_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 494.0
HKD1_k127_7263538_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 440.0
HKD1_k127_7263538_9 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 405.0
HKD1_k127_7286271_0 xanthine dehydrogenase activity - - - 0.0 1049.0
HKD1_k127_7286271_1 DNA topological change - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 553.0
HKD1_k127_7286271_2 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 522.0
HKD1_k127_7286271_3 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 256.0
HKD1_k127_7286271_4 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000003743 261.0
HKD1_k127_7286271_5 FR47-like protein K06976 - - 0.00000000000000000000000000000000000002051 156.0
HKD1_k127_7286722_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1355.0
HKD1_k127_7286722_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.05e-322 996.0
HKD1_k127_7286722_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 313.0
HKD1_k127_7286722_11 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004076 285.0
HKD1_k127_7286722_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000003011 235.0
HKD1_k127_7286722_13 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000000000000000003443 213.0
HKD1_k127_7286722_14 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000004996 216.0
HKD1_k127_7286722_15 MerR family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000003191 204.0
HKD1_k127_7286722_16 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000002838 175.0
HKD1_k127_7286722_17 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000002301 160.0
HKD1_k127_7286722_18 protein import - - - 0.000000000000000000000000001992 128.0
HKD1_k127_7286722_19 Type II secretory pathway component ExeA K02450,K12283 - - 0.0000000000000000005576 100.0
HKD1_k127_7286722_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.251e-252 790.0
HKD1_k127_7286722_20 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000001193 83.0
HKD1_k127_7286722_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000003113 55.0
HKD1_k127_7286722_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.691e-229 738.0
HKD1_k127_7286722_4 Belongs to the Orn Lys Arg decarboxylase class-II family K00928,K12526 - 2.7.2.4,4.1.1.20 1.577e-216 692.0
HKD1_k127_7286722_5 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 466.0
HKD1_k127_7286722_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 420.0
HKD1_k127_7286722_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 400.0
HKD1_k127_7286722_8 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 334.0
HKD1_k127_7286722_9 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 311.0
HKD1_k127_7342068_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.795e-207 660.0
HKD1_k127_7342068_1 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 411.0
HKD1_k127_7342068_2 radical SAM protein YgiQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 375.0
HKD1_k127_7342068_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000005198 211.0
HKD1_k127_7342068_4 - - - - 0.000000000000000001843 91.0
HKD1_k127_7342068_5 COG1585 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.0000003951 59.0
HKD1_k127_7361086_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.73e-255 805.0
HKD1_k127_7361086_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.454e-219 708.0
HKD1_k127_7361086_10 PFAM YicC-like - - - 0.00000000000000000000000000000000000000000000000000000000000000832 230.0
HKD1_k127_7361086_11 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000107 207.0
HKD1_k127_7361086_12 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000005297 212.0
HKD1_k127_7361086_13 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000006729 194.0
HKD1_k127_7361086_14 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000001669 175.0
HKD1_k127_7361086_15 PFAM Fimbrial assembly K02663 - - 0.000000000000000000000000000000000000000000001913 172.0
HKD1_k127_7361086_16 pilus assembly protein pilp K02665 - - 0.00000000000000000000000000000000000000000005804 167.0
HKD1_k127_7361086_17 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000007607 139.0
HKD1_k127_7361086_18 mRNA catabolic process - - - 0.00000000000000000000000000000002871 136.0
HKD1_k127_7361086_19 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000000000002421 124.0
HKD1_k127_7361086_2 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 3.445e-207 672.0
HKD1_k127_7361086_20 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000001162 115.0
HKD1_k127_7361086_21 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000008447 106.0
HKD1_k127_7361086_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 604.0
HKD1_k127_7361086_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 461.0
HKD1_k127_7361086_5 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 379.0
HKD1_k127_7361086_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 354.0
HKD1_k127_7361086_7 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 336.0
HKD1_k127_7361086_8 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 310.0
HKD1_k127_7361086_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000337 234.0
HKD1_k127_7476320_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 571.0
HKD1_k127_7476320_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 512.0
HKD1_k127_7476320_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 327.0
HKD1_k127_7476320_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009993 257.0
HKD1_k127_7476320_4 - - - - 0.000000000000000000000000000000000000000000000000001845 193.0
HKD1_k127_7476320_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000005661 151.0
HKD1_k127_7476320_6 - - - - 0.000000000000000000000000000006607 135.0
HKD1_k127_7476320_7 - - - - 0.000000000000000000003028 102.0
HKD1_k127_7476320_8 - - - - 0.00000000000000000001759 101.0
HKD1_k127_7487559_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 6.435e-291 899.0
HKD1_k127_7487559_1 Dehydrogenase K00114 - 1.1.2.8 8.024e-203 647.0
HKD1_k127_7487559_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 268.0
HKD1_k127_7487559_11 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001248 248.0
HKD1_k127_7487559_12 (Lipo)protein K04754 - - 0.000000000000000000000000000000000000000000000000001358 192.0
HKD1_k127_7487559_13 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000005141 186.0
HKD1_k127_7487559_14 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000005768 183.0
HKD1_k127_7487559_15 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000002088 164.0
HKD1_k127_7487559_16 MlaD protein K02067 - - 0.0000000000000000000000000000000000000007789 153.0
HKD1_k127_7487559_17 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000007849 146.0
HKD1_k127_7487559_18 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.0000000000000000000000000000000000003416 154.0
HKD1_k127_7487559_19 Di-heme cytochrome C peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000003477 142.0
HKD1_k127_7487559_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 569.0
HKD1_k127_7487559_20 YceI-like domain - - - 0.000000000000000000000002145 111.0
HKD1_k127_7487559_21 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000002253 115.0
HKD1_k127_7487559_23 - - - - 0.00000002145 68.0
HKD1_k127_7487559_24 Domain of unknown function (DUF4279) - - - 0.0000001511 60.0
HKD1_k127_7487559_25 - - - - 0.0000001808 62.0
HKD1_k127_7487559_26 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0000007885 61.0
HKD1_k127_7487559_27 NTP binding protein (Contains STAS domain) K07122 - - 0.00000107 57.0
HKD1_k127_7487559_3 PQQ-like domain K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 563.0
HKD1_k127_7487559_4 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 491.0
HKD1_k127_7487559_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 393.0
HKD1_k127_7487559_6 (ABC) transporter K02065 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 332.0
HKD1_k127_7487559_7 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 309.0
HKD1_k127_7487559_8 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 302.0
HKD1_k127_7487559_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
HKD1_k127_7503814_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 1.663e-258 835.0
HKD1_k127_7503814_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 9.411e-215 681.0
HKD1_k127_7503814_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 307.0
HKD1_k127_7503814_11 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 297.0
HKD1_k127_7503814_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000001303 239.0
HKD1_k127_7503814_13 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000007399 169.0
HKD1_k127_7503814_14 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000003668 168.0
HKD1_k127_7503814_15 Belongs to the transferase hexapeptide repeat family K00674 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.00000000000000000000000000000001177 128.0
HKD1_k127_7503814_16 Belongs to the skp family K06142 - - 0.0000000000000000000002237 105.0
HKD1_k127_7503814_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 621.0
HKD1_k127_7503814_3 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 430.0
HKD1_k127_7503814_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 405.0
HKD1_k127_7503814_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 379.0
HKD1_k127_7503814_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 349.0
HKD1_k127_7503814_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 342.0
HKD1_k127_7503814_8 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
HKD1_k127_7503814_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 321.0
HKD1_k127_7509288_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 530.0
HKD1_k127_7509288_1 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 490.0
HKD1_k127_7509288_10 Histidine phosphatase superfamily (branch 1) K08296 - - 0.000000000000000000000000000000000011 149.0
HKD1_k127_7509288_11 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000007687 115.0
HKD1_k127_7509288_12 PFAM RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000002026 112.0
HKD1_k127_7509288_2 signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 469.0
HKD1_k127_7509288_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 306.0
HKD1_k127_7509288_4 carbohydrate transport K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 311.0
HKD1_k127_7509288_5 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005941 288.0
HKD1_k127_7509288_6 FeS assembly SUF system protein SufT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005943 261.0
HKD1_k127_7509288_7 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
HKD1_k127_7509288_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000003336 182.0
HKD1_k127_7509288_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000002389 184.0
HKD1_k127_7535220_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1534.0
HKD1_k127_7535220_1 Hydroxymethylglutaryl-coenzyme A reductase K00054 - 1.1.1.88 9.607e-307 973.0
HKD1_k127_7535220_10 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.00000000000000000000000000000000000000000000000000000000001568 214.0
HKD1_k127_7535220_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000004063 201.0
HKD1_k127_7535220_12 GHMP kinases N terminal domain K00938 - 2.7.4.2 0.00000000000000000000000000000000000000000001789 174.0
HKD1_k127_7535220_13 MlaC protein K07323 - - 0.000000000000000000000000001661 121.0
HKD1_k127_7535220_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000886 119.0
HKD1_k127_7535220_15 Adenylate cyclase - - - 0.000000000000000000000001082 115.0
HKD1_k127_7535220_16 Histidine kinase K03407 - 2.7.13.3 0.00000007973 66.0
HKD1_k127_7535220_17 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.0001033 55.0
HKD1_k127_7535220_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 1.823e-233 732.0
HKD1_k127_7535220_3 Domain of unknown function (DUF3463) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 587.0
HKD1_k127_7535220_4 synthase K01641,K15311 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 529.0
HKD1_k127_7535220_5 L-lactate dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 434.0
HKD1_k127_7535220_6 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 361.0
HKD1_k127_7535220_7 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 308.0
HKD1_k127_7535220_8 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001122 264.0
HKD1_k127_7535220_9 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000011 224.0
HKD1_k127_7567310_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 511.0
HKD1_k127_7567310_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 430.0
HKD1_k127_7567310_2 Major Facilitator Superfamily K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 329.0
HKD1_k127_7567310_3 TIGRFAM 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 295.0
HKD1_k127_7567310_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003497 270.0
HKD1_k127_7567310_5 Hydrolase K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000002638 247.0
HKD1_k127_7567310_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000003291 167.0
HKD1_k127_7567310_7 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - 0.000000000000000000000000001094 115.0
HKD1_k127_7567310_8 small protein containing a coiled-coil domain - - - 0.000000000000057 74.0
HKD1_k127_7579818_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 366.0
HKD1_k127_7579818_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 322.0
HKD1_k127_7579818_2 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000001865 186.0
HKD1_k127_7579818_3 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000001507 63.0
HKD1_k127_7612363_0 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 527.0
HKD1_k127_7612363_1 PFAM PBS lyase HEAT domain protein - - - 0.0000000000002485 77.0
HKD1_k127_7612363_2 metallopeptidase activity K01183,K01278,K03561,K12287 - 3.2.1.14,3.4.14.5 0.00000003408 57.0
HKD1_k127_7634725_0 TonB dependent receptor K02014 - - 2.786e-313 978.0
HKD1_k127_7634725_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 2.585e-299 937.0
HKD1_k127_7634725_10 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 485.0
HKD1_k127_7634725_11 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 429.0
HKD1_k127_7634725_12 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 425.0
HKD1_k127_7634725_13 His Kinase A (phosphoacceptor) domain K07641,K10819 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 420.0
HKD1_k127_7634725_14 sulfate ABC transporter K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 372.0
HKD1_k127_7634725_15 TIGRFAM sulfate ABC transporter, inner membrane subunit CysT K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 335.0
HKD1_k127_7634725_16 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 346.0
HKD1_k127_7634725_17 Glutathione-dependent formaldehyde-activating enzyme K03396 - 4.4.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 304.0
HKD1_k127_7634725_18 KDP operon transcriptional regulatory protein KdpE K07667 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 254.0
HKD1_k127_7634725_19 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001063 251.0
HKD1_k127_7634725_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 4.122e-290 908.0
HKD1_k127_7634725_20 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000001007 235.0
HKD1_k127_7634725_21 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000002716 222.0
HKD1_k127_7634725_22 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000002168 244.0
HKD1_k127_7634725_23 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000001374 197.0
HKD1_k127_7634725_24 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000005063 169.0
HKD1_k127_7634725_25 GrpB protein - - - 0.000000000000000000000000000000000000000005748 163.0
HKD1_k127_7634725_26 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000003568 139.0
HKD1_k127_7634725_27 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001801 118.0
HKD1_k127_7634725_28 lactoylglutathione lyase activity - - - 0.000000000002236 72.0
HKD1_k127_7634725_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.058e-264 827.0
HKD1_k127_7634725_30 Belongs to the UPF0235 family K09131 - - 0.00000000006121 68.0
HKD1_k127_7634725_31 - - - - 0.00004497 54.0
HKD1_k127_7634725_32 Bacterial regulatory proteins, tetR family - - - 0.00005511 53.0
HKD1_k127_7634725_4 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 6.436e-225 726.0
HKD1_k127_7634725_5 FAD linked oxidase domain protein K05797 - 1.17.99.1 1.331e-214 679.0
HKD1_k127_7634725_6 DNA topological change - - - 1.419e-208 673.0
HKD1_k127_7634725_7 Tfp pilus assembly protein FimV - - - 2.443e-195 622.0
HKD1_k127_7634725_8 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 604.0
HKD1_k127_7634725_9 Magnesium transport protein CorA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 567.0
HKD1_k127_7637884_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1206.0
HKD1_k127_7637884_1 Putative amidoligase enzyme (DUF2126) - - - 0.0 1049.0
HKD1_k127_7637884_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 379.0
HKD1_k127_7637884_11 ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 319.0
HKD1_k127_7637884_12 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 298.0
HKD1_k127_7637884_13 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009554 279.0
HKD1_k127_7637884_14 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000002869 263.0
HKD1_k127_7637884_15 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000007794 241.0
HKD1_k127_7637884_16 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000006981 199.0
HKD1_k127_7637884_17 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.0000000000000000000000000000000000000000000003542 174.0
HKD1_k127_7637884_18 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000007297 165.0
HKD1_k127_7637884_19 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000002246 154.0
HKD1_k127_7637884_2 Belongs to the ClpA ClpB family K03694 - - 0.0 1047.0
HKD1_k127_7637884_20 Type II secretion system protein C - - - 0.0000000000000000000000000000000000008636 152.0
HKD1_k127_7637884_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000101 136.0
HKD1_k127_7637884_22 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000006518 98.0
HKD1_k127_7637884_23 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000009006 90.0
HKD1_k127_7637884_24 PFAM VanZ - - - 0.000000000004779 71.0
HKD1_k127_7637884_3 DNA segregation ATPase FtsK SpoIIIE K03466 - - 2.839e-273 860.0
HKD1_k127_7637884_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 8.233e-200 636.0
HKD1_k127_7637884_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 545.0
HKD1_k127_7637884_6 secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 493.0
HKD1_k127_7637884_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 429.0
HKD1_k127_7637884_8 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 404.0
HKD1_k127_7637884_9 General secretion pathway protein K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 420.0
HKD1_k127_7671104_0 Peptidase C39 family K13409 - - 1.115e-260 829.0
HKD1_k127_7671104_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 425.0
HKD1_k127_7671104_2 HlyD family secretion protein K13408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 339.0
HKD1_k127_7671104_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 302.0
HKD1_k127_7671104_4 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000002418 213.0
HKD1_k127_7671104_6 Aspartyl protease - - - 0.0000000000000000000000000000000006651 151.0
HKD1_k127_7671104_7 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000008685 137.0
HKD1_k127_7671104_8 Beta-lactamase - - - 0.00002234 57.0
HKD1_k127_772630_1 light absorption - - - 0.000000000009049 75.0
HKD1_k127_772630_2 NMT1-like family - - - 0.00000000001811 66.0
HKD1_k127_772630_3 Carboxymuconolactone decarboxylase family - - - 0.0000000005226 60.0
HKD1_k127_7839772_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.55e-304 948.0
HKD1_k127_7839772_1 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 3.456e-275 872.0
HKD1_k127_7839772_10 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 394.0
HKD1_k127_7839772_11 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 370.0
HKD1_k127_7839772_12 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 336.0
HKD1_k127_7839772_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 297.0
HKD1_k127_7839772_14 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.0000000000000000000000000000001785 125.0
HKD1_k127_7839772_15 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.0000000000000000000000000000002482 129.0
HKD1_k127_7839772_16 FMN_bind K19339 - - 0.000000000000000000000000007093 126.0
HKD1_k127_7839772_17 FMN_bind - - - 0.0000000000002885 77.0
HKD1_k127_7839772_2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01200,K01214 - 3.2.1.41,3.2.1.68 3.14e-223 748.0
HKD1_k127_7839772_3 Belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 1.279e-218 696.0
HKD1_k127_7839772_4 Radical SAM superfamily K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 579.0
HKD1_k127_7839772_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 550.0
HKD1_k127_7839772_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 539.0
HKD1_k127_7839772_7 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 472.0
HKD1_k127_7839772_8 Surface antigen variable number K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 446.0
HKD1_k127_7839772_9 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04101,K05713 - 1.13.11.16,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 407.0
HKD1_k127_7879167_1 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 423.0
HKD1_k127_7879167_2 SnoaL-like domain - - - 0.00000000000001908 85.0
HKD1_k127_7879167_3 NMT1-like family - - - 0.000000000006979 68.0
HKD1_k127_7893508_0 ABC transporter transmembrane region K06147,K11085 - - 3.522e-200 640.0
HKD1_k127_7893508_1 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 503.0
HKD1_k127_7893508_10 deacetylase K06986 - - 0.00000000000000000000000000000000000000000000000000007933 199.0
HKD1_k127_7893508_11 DUF218 domain - - - 0.00000000000000000000000000000000000000000000003871 178.0
HKD1_k127_7893508_12 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000001381 146.0
HKD1_k127_7893508_14 RNA recognition motif - - - 0.00000000000000000000000000000008123 126.0
HKD1_k127_7893508_15 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000004251 122.0
HKD1_k127_7893508_16 - - - - 0.000000000000000000000000005406 124.0
HKD1_k127_7893508_17 - - - - 0.00000000000000000000000001744 115.0
HKD1_k127_7893508_18 - - - - 0.000000000000000000000001255 115.0
HKD1_k127_7893508_19 YCII-related domain - - - 0.00000000000000000000000897 105.0
HKD1_k127_7893508_2 metallo-beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 414.0
HKD1_k127_7893508_20 - - - - 0.000000000000000000002559 104.0
HKD1_k127_7893508_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 346.0
HKD1_k127_7893508_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 334.0
HKD1_k127_7893508_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 259.0
HKD1_k127_7893508_6 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009476 250.0
HKD1_k127_7893508_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000155 231.0
HKD1_k127_7893508_8 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000000000002706 198.0
HKD1_k127_7893508_9 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000000000915 198.0
HKD1_k127_7923878_0 Elongation factor SelB, winged helix K03833 - - 7.229e-205 661.0
HKD1_k127_7923878_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 559.0
HKD1_k127_7923878_2 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 497.0
HKD1_k127_7923878_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 448.0
HKD1_k127_7923878_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000007288 254.0
HKD1_k127_7923878_5 IMP dehydrogenase activity K04767 - - 0.000000000003384 76.0
HKD1_k127_7923878_6 Elongation factor SelB, winged helix K03833 - - 0.000000002053 58.0
HKD1_k127_7923878_7 - - - - 0.0001078 46.0
HKD1_k127_7952183_0 efflux pump K18138,K18322 - - 0.0 1384.0
HKD1_k127_7952183_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.421e-213 677.0
HKD1_k127_7952183_10 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003884 244.0
HKD1_k127_7952183_11 TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000303 179.0
HKD1_k127_7952183_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000007887 155.0
HKD1_k127_7952183_13 transcriptional - - - 0.0000000000000000000000000000007886 128.0
HKD1_k127_7952183_14 Protein of unknown function, DUF255 K01829 - 5.3.4.1 0.0000000000000000007535 100.0
HKD1_k127_7952183_15 nuclear chromosome segregation K03615 - - 0.0002986 49.0
HKD1_k127_7952183_16 WD-40 repeat-containing protein - - - 0.0003481 53.0
HKD1_k127_7952183_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 517.0
HKD1_k127_7952183_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 433.0
HKD1_k127_7952183_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 396.0
HKD1_k127_7952183_5 FAD binding domain K00486 - 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 392.0
HKD1_k127_7952183_6 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 393.0
HKD1_k127_7952183_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 339.0
HKD1_k127_7952183_8 PFAM Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 306.0
HKD1_k127_7952183_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003492 245.0
HKD1_k127_837888_0 acyl-CoA dehydrogenase K06445 GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - 3.689e-277 874.0
HKD1_k127_837888_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 3.982e-212 670.0
HKD1_k127_837888_10 PFAM PspA IM30 family protein K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
HKD1_k127_837888_11 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007273 229.0
HKD1_k127_837888_12 - - - - 0.0000000000000000000000000000000000000000000001086 175.0
HKD1_k127_837888_13 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000001379 181.0
HKD1_k127_837888_14 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000001289 158.0
HKD1_k127_837888_15 transport system involved in gliding motility, auxiliary component - - - 0.00000000000000000000000000000000000005406 147.0
HKD1_k127_837888_16 - - - - 0.0000000000000000000000000000000000933 141.0
HKD1_k127_837888_17 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000005478 103.0
HKD1_k127_837888_18 PspC domain - - - 0.0000000000000000000003606 102.0
HKD1_k127_837888_19 Phage shock protein B K03970 - - 0.000000000000002283 78.0
HKD1_k127_837888_2 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 497.0
HKD1_k127_837888_20 membrane K02451,K03832 - - 0.0000000002115 70.0
HKD1_k127_837888_21 Protein of unknown function (DUF2845) - - - 0.00000001123 64.0
HKD1_k127_837888_22 - - - - 0.000008332 52.0
HKD1_k127_837888_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 464.0
HKD1_k127_837888_4 Sigma-54 interaction domain K03974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 426.0
HKD1_k127_837888_5 sensor diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 427.0
HKD1_k127_837888_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 424.0
HKD1_k127_837888_7 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 420.0
HKD1_k127_837888_8 NADPH quinone K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 388.0
HKD1_k127_837888_9 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 326.0
HKD1_k127_93155_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.27e-284 891.0
HKD1_k127_93155_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 8.13e-207 649.0
HKD1_k127_93155_10 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 356.0
HKD1_k127_93155_11 ABC transporter, ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 338.0
HKD1_k127_93155_12 Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 300.0
HKD1_k127_93155_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000904 252.0
HKD1_k127_93155_14 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000004417 232.0
HKD1_k127_93155_15 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000003629 223.0
HKD1_k127_93155_16 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000004697 211.0
HKD1_k127_93155_17 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000001394 196.0
HKD1_k127_93155_18 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000009757 154.0
HKD1_k127_93155_19 peptidase S16, lon K07157 - - 0.000000000000000000000000000000000000001537 168.0
HKD1_k127_93155_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 587.0
HKD1_k127_93155_20 COG1544 Ribosome-associated protein Y (PSrp-1) K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000135 143.0
HKD1_k127_93155_21 Rubredoxin - - - 0.0000000000000000000000002072 106.0
HKD1_k127_93155_22 Belongs to the BolA IbaG family - - - 0.000000000000000000003973 95.0
HKD1_k127_93155_23 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.00000000000007947 79.0
HKD1_k127_93155_24 - - - - 0.0000002744 60.0
HKD1_k127_93155_3 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 565.0
HKD1_k127_93155_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 531.0
HKD1_k127_93155_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 526.0
HKD1_k127_93155_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 497.0
HKD1_k127_93155_7 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 448.0
HKD1_k127_93155_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 422.0
HKD1_k127_93155_9 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 385.0