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Overview

ID MAG01752
Name HKD1_bin.71
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-39
Genus DAHVFK01
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 7.27
GC content (%) 68.0
N50 (bp) 20,561
Genome size (bp) 3,683,272

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3734

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1014231_0 promotes GTP-dependent translocation of the ribosome during translation K02355 - - 1.998e-272 857.0
HKD1_k127_1014231_1 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846 - 4.4.1.24 2.455e-215 672.0
HKD1_k127_1014231_10 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 376.0
HKD1_k127_1014231_11 Gliding motility protein GldG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 362.0
HKD1_k127_1014231_12 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 339.0
HKD1_k127_1014231_13 Belongs to the SUA5 family K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 333.0
HKD1_k127_1014231_14 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 297.0
HKD1_k127_1014231_15 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002519 273.0
HKD1_k127_1014231_16 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 239.0
HKD1_k127_1014231_17 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005986 237.0
HKD1_k127_1014231_18 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000007702 218.0
HKD1_k127_1014231_19 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000008587 211.0
HKD1_k127_1014231_2 Protein of unknown function (DUF3141) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 532.0
HKD1_k127_1014231_20 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000005471 203.0
HKD1_k127_1014231_21 SAF K16845 - 4.4.1.24 0.00000000000000000000000000000000000000001592 154.0
HKD1_k127_1014231_22 succinate dehydrogenase K00247 - - 0.000000000000000000000000000000000000003409 154.0
HKD1_k127_1014231_23 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000001772 119.0
HKD1_k127_1014231_24 succinate dehydrogenase K00246 - - 0.00000000000000000000003183 112.0
HKD1_k127_1014231_25 ChrR Cupin-like domain - - - 0.00000000000000000003596 90.0
HKD1_k127_1014231_26 Domain of unknown function (DUF4340) - - - 0.00000000000000001021 96.0
HKD1_k127_1014231_27 - - - - 0.000000000000000144 81.0
HKD1_k127_1014231_3 Mandelate Racemase Muconate Lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 496.0
HKD1_k127_1014231_4 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 503.0
HKD1_k127_1014231_5 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 439.0
HKD1_k127_1014231_6 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 447.0
HKD1_k127_1014231_7 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 425.0
HKD1_k127_1014231_8 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 402.0
HKD1_k127_1014231_9 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 370.0
HKD1_k127_1031781_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1469.0
HKD1_k127_1031781_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.912e-284 884.0
HKD1_k127_1031781_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000002449 196.0
HKD1_k127_1031781_11 Branched-chain amino acid permease - - - 0.0000000000000000000000000000000000000000000000000001059 194.0
HKD1_k127_1031781_12 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000006402 185.0
HKD1_k127_1031781_13 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000000147 179.0
HKD1_k127_1031781_14 branched-chain amino acid - - - 0.0000000000000004305 86.0
HKD1_k127_1031781_2 Belongs to the peptidase M16 family K07263 - - 1.619e-271 862.0
HKD1_k127_1031781_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 562.0
HKD1_k127_1031781_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 567.0
HKD1_k127_1031781_5 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 561.0
HKD1_k127_1031781_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
HKD1_k127_1031781_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000003685 252.0
HKD1_k127_1031781_8 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
HKD1_k127_1031781_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000005379 212.0
HKD1_k127_1033976_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1467.0
HKD1_k127_1033976_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1166.0
HKD1_k127_1033976_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 368.0
HKD1_k127_1033976_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 331.0
HKD1_k127_1033976_12 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 321.0
HKD1_k127_1033976_13 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 315.0
HKD1_k127_1033976_14 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 301.0
HKD1_k127_1033976_15 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 296.0
HKD1_k127_1033976_16 50S ribosomal protein L4 K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 292.0
HKD1_k127_1033976_17 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 286.0
HKD1_k127_1033976_18 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004464 276.0
HKD1_k127_1033976_19 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
HKD1_k127_1033976_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.114e-292 907.0
HKD1_k127_1033976_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000702 255.0
HKD1_k127_1033976_21 Ribosomal protein L16p/L10e K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007113 238.0
HKD1_k127_1033976_22 ABC transporter K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000001623 239.0
HKD1_k127_1033976_23 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003942 223.0
HKD1_k127_1033976_24 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000001935 220.0
HKD1_k127_1033976_25 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000003172 212.0
HKD1_k127_1033976_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000003419 217.0
HKD1_k127_1033976_27 dehydratase - - - 0.000000000000000000000000000000000000000000000000000003041 195.0
HKD1_k127_1033976_28 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000000000001413 186.0
HKD1_k127_1033976_29 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000003185 190.0
HKD1_k127_1033976_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.694e-237 736.0
HKD1_k127_1033976_30 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000002913 184.0
HKD1_k127_1033976_31 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000361 183.0
HKD1_k127_1033976_32 NUDIX domain K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000004996 183.0
HKD1_k127_1033976_33 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000001351 166.0
HKD1_k127_1033976_34 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000001589 163.0
HKD1_k127_1033976_35 Protein of unknown function (DUF2946) - - - 0.0000000000000000000000000000000000000000824 158.0
HKD1_k127_1033976_36 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000005833 145.0
HKD1_k127_1033976_37 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000008543 143.0
HKD1_k127_1033976_38 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000002198 144.0
HKD1_k127_1033976_39 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000006184 129.0
HKD1_k127_1033976_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.372e-227 717.0
HKD1_k127_1033976_40 Ribonuclease K01167 - 3.1.27.3 0.000000000000000000000000002004 129.0
HKD1_k127_1033976_41 Barstar (barnase inhibitor) - - - 0.000000000000000000000001073 111.0
HKD1_k127_1033976_42 Putative regulatory protein - - - 0.000000000000000000000001506 112.0
HKD1_k127_1033976_43 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000000003111 88.0
HKD1_k127_1033976_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 455.0
HKD1_k127_1033976_6 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 428.0
HKD1_k127_1033976_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 406.0
HKD1_k127_1033976_8 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 388.0
HKD1_k127_1033976_9 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 394.0
HKD1_k127_1041363_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 305.0
HKD1_k127_1041363_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009923 260.0
HKD1_k127_1041363_2 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
HKD1_k127_1041363_3 nuclease activity K18828 - - 0.0000000000000000000000000000000000000000003942 166.0
HKD1_k127_1041363_4 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000001925 132.0
HKD1_k127_1041363_5 PFAM PIN domain - - - 0.00000000000000000000000001242 113.0
HKD1_k127_1041363_6 - K21495 - - 0.0000000000000000000008904 97.0
HKD1_k127_1041363_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000252 61.0
HKD1_k127_1050001_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.309e-220 692.0
HKD1_k127_1050001_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 407.0
HKD1_k127_1050001_2 PFAM ATP-binding region ATPase domain protein - - - 0.000007112 48.0
HKD1_k127_1069332_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 566.0
HKD1_k127_1069332_1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 341.0
HKD1_k127_1069332_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000002029 216.0
HKD1_k127_1069332_3 Cytochrome B561 - - - 0.00000000000000000000000000000000000000000000000000000004543 210.0
HKD1_k127_1069332_4 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000009625 64.0
HKD1_k127_1071589_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1264.0
HKD1_k127_1071589_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.219e-215 686.0
HKD1_k127_1071589_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 481.0
HKD1_k127_1071589_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 484.0
HKD1_k127_1071589_12 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 452.0
HKD1_k127_1071589_13 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 439.0
HKD1_k127_1071589_14 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 396.0
HKD1_k127_1071589_15 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 388.0
HKD1_k127_1071589_16 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 389.0
HKD1_k127_1071589_17 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 372.0
HKD1_k127_1071589_18 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 352.0
HKD1_k127_1071589_19 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 349.0
HKD1_k127_1071589_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.091e-198 631.0
HKD1_k127_1071589_20 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 334.0
HKD1_k127_1071589_21 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 314.0
HKD1_k127_1071589_22 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001679 283.0
HKD1_k127_1071589_23 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003327 268.0
HKD1_k127_1071589_24 AIR synthase related protein, N-terminal domain K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000151 260.0
HKD1_k127_1071589_25 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000001192 239.0
HKD1_k127_1071589_26 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000004272 203.0
HKD1_k127_1071589_27 POTRA domain, FtsQ-type - - - 0.0000000000000000000000000000000000000000000002358 177.0
HKD1_k127_1071589_28 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000002288 168.0
HKD1_k127_1071589_29 RimM N-terminal domain K02860 - - 0.0000000000000000000000000000000000007001 145.0
HKD1_k127_1071589_3 type II secretion system protein K02653 - - 2.502e-196 618.0
HKD1_k127_1071589_30 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000001752 139.0
HKD1_k127_1071589_31 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000501 124.0
HKD1_k127_1071589_32 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000001178 85.0
HKD1_k127_1071589_33 Protein of unknown function (DUF721) - - - 0.00001926 56.0
HKD1_k127_1071589_34 - - - - 0.0006171 45.0
HKD1_k127_1071589_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 614.0
HKD1_k127_1071589_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 573.0
HKD1_k127_1071589_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 528.0
HKD1_k127_1071589_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 501.0
HKD1_k127_1071589_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 490.0
HKD1_k127_1071589_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 486.0
HKD1_k127_1081418_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 511.0
HKD1_k127_1081418_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 411.0
HKD1_k127_1081418_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000003173 153.0
HKD1_k127_1081418_3 - - - - 0.0000000000000000000004723 104.0
HKD1_k127_1081418_4 - - - - 0.00000000000000001955 86.0
HKD1_k127_1083716_0 Fumarylacetoacetate hydrolase - - - 0.00000000000000000000000000000000000000000000000000000005882 219.0
HKD1_k127_1083716_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000002287 194.0
HKD1_k127_1083716_3 beta-lactamase domain protein K05555 - - 0.000000000000000000000000000000000009444 143.0
HKD1_k127_1083716_4 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000001393 134.0
HKD1_k127_1083716_5 Sulfatase - - - 0.00000000000000000000000003207 114.0
HKD1_k127_1083716_6 Transcriptional regulator K04033 - - 0.0000000000000000000000007021 117.0
HKD1_k127_1083716_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000002115 74.0
HKD1_k127_1083716_8 PFAM HNH endonuclease - - - 0.00001119 52.0
HKD1_k127_1112525_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.297e-269 840.0
HKD1_k127_1112525_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 4.208e-248 777.0
HKD1_k127_1152532_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.599e-249 798.0
HKD1_k127_1152532_1 lipoprotein releasing system, transmembrane protein, LolC E family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 502.0
HKD1_k127_1152532_10 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
HKD1_k127_1152532_11 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 329.0
HKD1_k127_1152532_12 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 309.0
HKD1_k127_1152532_13 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 317.0
HKD1_k127_1152532_14 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 300.0
HKD1_k127_1152532_15 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002536 271.0
HKD1_k127_1152532_16 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000001657 233.0
HKD1_k127_1152532_17 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000003749 202.0
HKD1_k127_1152532_18 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000000009363 173.0
HKD1_k127_1152532_19 Universal stress protein family - - - 0.0000000000000000000000000000000000000404 147.0
HKD1_k127_1152532_2 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 478.0
HKD1_k127_1152532_20 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000007808 145.0
HKD1_k127_1152532_21 - - - - 0.0000000000000000000001999 102.0
HKD1_k127_1152532_22 Protein of unknown function (DUF1648) - - - 0.00000000003396 70.0
HKD1_k127_1152532_3 Methionine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 420.0
HKD1_k127_1152532_4 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 409.0
HKD1_k127_1152532_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 370.0
HKD1_k127_1152532_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 388.0
HKD1_k127_1152532_7 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 361.0
HKD1_k127_1152532_8 Abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 376.0
HKD1_k127_1152532_9 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 339.0
HKD1_k127_1159493_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 621.0
HKD1_k127_1159493_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 338.0
HKD1_k127_1159493_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007732 271.0
HKD1_k127_1159493_3 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000005743 237.0
HKD1_k127_1159493_4 - - - - 0.000000000000000001019 98.0
HKD1_k127_1168512_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 0.0 1228.0
HKD1_k127_1168512_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1166.0
HKD1_k127_1168512_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 397.0
HKD1_k127_1168512_11 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 362.0
HKD1_k127_1168512_12 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
HKD1_k127_1168512_13 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 304.0
HKD1_k127_1168512_14 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 311.0
HKD1_k127_1168512_15 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001375 300.0
HKD1_k127_1168512_16 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001632 256.0
HKD1_k127_1168512_17 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000001584 263.0
HKD1_k127_1168512_18 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000000002734 207.0
HKD1_k127_1168512_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000002953 200.0
HKD1_k127_1168512_2 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 1.429e-270 848.0
HKD1_k127_1168512_20 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.00000000000000000000000000000000000000000000000000005818 205.0
HKD1_k127_1168512_21 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000004157 188.0
HKD1_k127_1168512_22 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000006581 158.0
HKD1_k127_1168512_23 - - - - 0.0000000000000001052 87.0
HKD1_k127_1168512_3 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.119e-225 715.0
HKD1_k127_1168512_4 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 5.925e-211 688.0
HKD1_k127_1168512_5 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 591.0
HKD1_k127_1168512_6 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 565.0
HKD1_k127_1168512_7 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 494.0
HKD1_k127_1168512_8 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 460.0
HKD1_k127_1168512_9 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 437.0
HKD1_k127_1188980_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 612.0
HKD1_k127_1188980_1 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 288.0
HKD1_k127_1188980_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 258.0
HKD1_k127_1188980_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001503 177.0
HKD1_k127_1190312_0 NADP-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 438.0
HKD1_k127_1190312_1 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 343.0
HKD1_k127_1190312_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000859 191.0
HKD1_k127_1190312_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000133 98.0
HKD1_k127_1190312_5 Helix-turn-helix domain - - - 0.0000000000000000002763 91.0
HKD1_k127_1192753_0 RESPONSE REGULATOR receiver - - - 2.826e-195 616.0
HKD1_k127_1192753_1 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 426.0
HKD1_k127_1192753_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 351.0
HKD1_k127_1192753_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001346 272.0
HKD1_k127_1209391_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 4.046e-266 838.0
HKD1_k127_1209391_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 5.961e-239 748.0
HKD1_k127_1209391_10 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 347.0
HKD1_k127_1209391_11 Carboxylesterase family K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 335.0
HKD1_k127_1209391_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 323.0
HKD1_k127_1209391_13 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 305.0
HKD1_k127_1209391_14 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006186 272.0
HKD1_k127_1209391_15 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000003278 235.0
HKD1_k127_1209391_16 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000005001 209.0
HKD1_k127_1209391_17 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000007268 179.0
HKD1_k127_1209391_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000002095 169.0
HKD1_k127_1209391_19 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000001335 161.0
HKD1_k127_1209391_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 8.268e-226 712.0
HKD1_k127_1209391_20 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000003983 155.0
HKD1_k127_1209391_21 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000687 156.0
HKD1_k127_1209391_22 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000008181 156.0
HKD1_k127_1209391_23 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000001076 146.0
HKD1_k127_1209391_24 Thioesterase superfamily - - - 0.0000000000000000000000000000000000008687 143.0
HKD1_k127_1209391_25 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000001206 111.0
HKD1_k127_1209391_27 - - - - 0.0003933 50.0
HKD1_k127_1209391_3 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 618.0
HKD1_k127_1209391_4 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 543.0
HKD1_k127_1209391_5 ABC transporter K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 400.0
HKD1_k127_1209391_6 Zinc-binding dehydrogenase K12957,K13953,K19961 - 1.1.1.1,1.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 387.0
HKD1_k127_1209391_7 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 377.0
HKD1_k127_1209391_8 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 345.0
HKD1_k127_1209391_9 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 343.0
HKD1_k127_1219899_0 Binding protein dependent transporter membrane component K05773,K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000002327 247.0
HKD1_k127_1219899_1 molybdopterin-guanine dinucleotide biosynthesis protein b K03753 - - 0.0000000000000000000000000000000000000000000000000000000000005059 226.0
HKD1_k127_1219899_2 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000003892 219.0
HKD1_k127_1219899_3 COG2998 ABC-type tungstate transport system, permease component K05772 - - 0.00000000000000000000000000000006293 126.0
HKD1_k127_1257787_0 AMP-dependent synthetase and ligase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 541.0
HKD1_k127_1257787_1 involved in cell wall biogenesis K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 316.0
HKD1_k127_1276898_0 Histidine kinase K07646 - 2.7.13.3 3.278e-289 914.0
HKD1_k127_1276898_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007462 292.0
HKD1_k127_1276898_2 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005811 257.0
HKD1_k127_1276898_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000001406 234.0
HKD1_k127_1276898_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000006826 221.0
HKD1_k127_1276898_5 Glyoxalase bleomycin resistance - - - 0.000000000000000000000000000000000000000000000000000003707 194.0
HKD1_k127_1276898_6 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.0000000000000000000000000000000003015 138.0
HKD1_k127_1276898_7 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000003226 135.0
HKD1_k127_1278379_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 515.0
HKD1_k127_1278379_1 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000008507 225.0
HKD1_k127_1289817_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 6.533e-247 773.0
HKD1_k127_1289817_1 Sugar (and other) transporter K08369 - - 3.799e-222 695.0
HKD1_k127_1289817_10 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000007546 188.0
HKD1_k127_1289817_11 Conserved hypothetical protein (Lin0512_fam) - - - 0.0000000000000000000000000000000000000001164 158.0
HKD1_k127_1289817_12 SMART Cold shock protein K03704 - - 0.00000000000000000000000000006383 118.0
HKD1_k127_1289817_13 Cold shock protein K03704 - - 0.00000000000000000000000002602 111.0
HKD1_k127_1289817_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000001017 112.0
HKD1_k127_1289817_15 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000001591 107.0
HKD1_k127_1289817_16 Belongs to the UPF0337 (CsbD) family - - - 0.0000006536 54.0
HKD1_k127_1289817_2 Aldehyde oxidase and xanthine dehydrogenase K00256 - 1.3.99.16 6.126e-203 664.0
HKD1_k127_1289817_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 527.0
HKD1_k127_1289817_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 464.0
HKD1_k127_1289817_5 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 442.0
HKD1_k127_1289817_6 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003095 283.0
HKD1_k127_1289817_7 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001837 252.0
HKD1_k127_1289817_8 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000006844 225.0
HKD1_k127_1289817_9 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000001674 211.0
HKD1_k127_129866_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 544.0
HKD1_k127_129866_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 387.0
HKD1_k127_129866_2 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004096 279.0
HKD1_k127_129866_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000008513 261.0
HKD1_k127_129866_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 261.0
HKD1_k127_129866_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000127 226.0
HKD1_k127_129866_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0005371 47.0
HKD1_k127_1378924_0 ABC transporter transmembrane region K11004 - - 1.038e-271 852.0
HKD1_k127_1378924_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 9.242e-211 661.0
HKD1_k127_1378924_10 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 367.0
HKD1_k127_1378924_11 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 364.0
HKD1_k127_1378924_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001102 259.0
HKD1_k127_1378924_13 PFAM Cytochrome C1 K00413 - - 0.000000000000000000000000000001178 123.0
HKD1_k127_1378924_2 PFAM sigma-54 factor interaction domain-containing protein - - - 4.362e-201 651.0
HKD1_k127_1378924_3 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 518.0
HKD1_k127_1378924_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 513.0
HKD1_k127_1378924_5 TIGRFAM type I secretion membrane fusion protein, HlyD K02022,K11003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 469.0
HKD1_k127_1378924_6 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 461.0
HKD1_k127_1378924_7 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 434.0
HKD1_k127_1378924_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 435.0
HKD1_k127_1378924_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 425.0
HKD1_k127_1382041_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.282e-252 788.0
HKD1_k127_1382041_1 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 428.0
HKD1_k127_1382041_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001316 288.0
HKD1_k127_1395315_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1057.0
HKD1_k127_1395315_1 TRAP dicarboxylate transporter, DctM subunit K11690 - - 4.531e-222 696.0
HKD1_k127_1395315_10 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 294.0
HKD1_k127_1395315_2 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 1.582e-194 617.0
HKD1_k127_1395315_3 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 610.0
HKD1_k127_1395315_4 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 519.0
HKD1_k127_1395315_5 C4-dicarboxylate ABC transporter K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 504.0
HKD1_k127_1395315_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 490.0
HKD1_k127_1395315_7 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 472.0
HKD1_k127_1395315_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 460.0
HKD1_k127_1395315_9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 424.0
HKD1_k127_140771_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 450.0
HKD1_k127_140771_1 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000001464 236.0
HKD1_k127_140771_2 AntiSigma factor K07167 - - 0.00000000000000000000000000000000000000000000000000000000000001098 229.0
HKD1_k127_140771_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000222 186.0
HKD1_k127_140771_4 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000008263 161.0
HKD1_k127_140771_5 - - - - 0.000000000000000000000000000000003709 133.0
HKD1_k127_1407716_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.39e-196 619.0
HKD1_k127_1407716_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 564.0
HKD1_k127_1407716_2 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000001783 105.0
HKD1_k127_1417494_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.698e-226 727.0
HKD1_k127_1417494_1 Domain of unknown function (DUF4398) - - - 0.000000000000000000000000000000000000000001125 169.0
HKD1_k127_1417494_2 - - - - 0.00000000000000000000000000000005475 138.0
HKD1_k127_1417494_3 - - - - 0.00000437 58.0
HKD1_k127_1464849_0 Sulfatase - - - 3.543e-286 884.0
HKD1_k127_1464849_1 Arylsulfatase K01130 - 3.1.6.1 1.729e-212 682.0
HKD1_k127_1464849_2 helicase K03657 - 3.6.4.12 9.01e-200 632.0
HKD1_k127_1464849_3 Radical SAM superfamily K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 522.0
HKD1_k127_1464849_4 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 421.0
HKD1_k127_1464849_5 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000000000000000000000104 190.0
HKD1_k127_1464849_6 - - - - 0.00000000000000000000000000000000009187 138.0
HKD1_k127_1464849_7 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000882 103.0
HKD1_k127_1468837_0 Adenylate K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 557.0
HKD1_k127_1468837_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 522.0
HKD1_k127_1468837_2 Peptidase M50 K16922 - - 0.00000000000002842 84.0
HKD1_k127_1468837_3 Putative zinc- or iron-chelating domain - - - 0.000000000001375 72.0
HKD1_k127_1468837_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000005864 59.0
HKD1_k127_1486614_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.258e-233 736.0
HKD1_k127_1486614_1 Amidohydrolase family - - - 2.106e-223 706.0
HKD1_k127_1486614_10 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 501.0
HKD1_k127_1486614_11 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 491.0
HKD1_k127_1486614_12 maleylacetate reductase K00217 - 1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 449.0
HKD1_k127_1486614_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 361.0
HKD1_k127_1486614_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04098 - 1.13.11.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 348.0
HKD1_k127_1486614_15 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 329.0
HKD1_k127_1486614_16 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 321.0
HKD1_k127_1486614_17 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 306.0
HKD1_k127_1486614_18 PFAM Carbohydrate-selective porin OprB K07267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 299.0
HKD1_k127_1486614_19 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006969 280.0
HKD1_k127_1486614_2 AMP-binding enzyme C-terminal domain K00666 - - 1.264e-212 682.0
HKD1_k127_1486614_20 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000381 265.0
HKD1_k127_1486614_21 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003871 250.0
HKD1_k127_1486614_22 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000007975 227.0
HKD1_k127_1486614_23 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000000000000000000000002432 184.0
HKD1_k127_1486614_24 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000003089 198.0
HKD1_k127_1486614_25 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000001222 192.0
HKD1_k127_1486614_26 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000327 188.0
HKD1_k127_1486614_27 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000109 181.0
HKD1_k127_1486614_28 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000000000000000000196 152.0
HKD1_k127_1486614_29 SnoaL-like domain - - - 0.0000000000000000103 97.0
HKD1_k127_1486614_3 TonB dependent receptor K02014 - - 9.708e-199 643.0
HKD1_k127_1486614_30 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.00000000004196 75.0
HKD1_k127_1486614_31 EamA-like transporter family - - - 0.00000006672 63.0
HKD1_k127_1486614_32 hyperosmotic response K04065 - - 0.00005975 54.0
HKD1_k127_1486614_33 - - - - 0.0001659 47.0
HKD1_k127_1486614_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 602.0
HKD1_k127_1486614_5 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 552.0
HKD1_k127_1486614_6 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 528.0
HKD1_k127_1486614_7 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 528.0
HKD1_k127_1486614_8 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 510.0
HKD1_k127_1486614_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 496.0
HKD1_k127_150181_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 490.0
HKD1_k127_150181_1 cell wall organization K01179,K02343,K06178 - 2.7.7.7,3.2.1.4,5.4.99.22 0.00000007109 57.0
HKD1_k127_1511263_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.498e-250 783.0
HKD1_k127_1511263_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 321.0
HKD1_k127_1511263_2 Chaperone protein TorD - - - 0.00000000000000000000000000000000539 143.0
HKD1_k127_1511263_3 - - - - 0.00002164 49.0
HKD1_k127_1524655_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 374.0
HKD1_k127_1524655_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 330.0
HKD1_k127_1524655_2 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 302.0
HKD1_k127_1524655_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000001958 152.0
HKD1_k127_1534474_0 protein involved in response to NO - - - 0.000000000000000000000000000000000000000000000000000000000000000002221 246.0
HKD1_k127_1534474_1 transcriptional regulator K13771 - - 0.000000000000000000000000000000000000000000005856 167.0
HKD1_k127_1534474_2 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000002513 129.0
HKD1_k127_1557295_0 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003522 238.0
HKD1_k127_1557295_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000008407 188.0
HKD1_k127_1557295_2 hopanoid biosynthesis associated membrane protein HpnM K07323 - - 0.0000000007497 71.0
HKD1_k127_1561119_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 486.0
HKD1_k127_1561119_1 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 367.0
HKD1_k127_1561119_2 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 350.0
HKD1_k127_1561119_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000001401 173.0
HKD1_k127_1561119_4 PFAM NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000000000004463 169.0
HKD1_k127_157796_0 Domain of unknown function (DUF3400) - - - 0.0 1729.0
HKD1_k127_157796_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1168.0
HKD1_k127_157796_10 Rod shape-determining protein MreB K03569 - - 5.169e-204 638.0
HKD1_k127_157796_11 twitching motility protein K02669 - - 1.306e-201 631.0
HKD1_k127_157796_12 Mur ligase family, catalytic domain K02558 - 6.3.2.45 1.176e-198 629.0
HKD1_k127_157796_13 RNB K01147 - 3.1.13.1 1.796e-194 625.0
HKD1_k127_157796_14 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 613.0
HKD1_k127_157796_15 Aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 599.0
HKD1_k127_157796_16 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 593.0
HKD1_k127_157796_17 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 551.0
HKD1_k127_157796_18 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 513.0
HKD1_k127_157796_19 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 511.0
HKD1_k127_157796_2 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 1114.0
HKD1_k127_157796_20 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 507.0
HKD1_k127_157796_21 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 495.0
HKD1_k127_157796_22 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 498.0
HKD1_k127_157796_23 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 484.0
HKD1_k127_157796_24 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 457.0
HKD1_k127_157796_25 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 454.0
HKD1_k127_157796_26 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 452.0
HKD1_k127_157796_27 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 413.0
HKD1_k127_157796_28 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 420.0
HKD1_k127_157796_29 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 402.0
HKD1_k127_157796_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 6.811e-259 812.0
HKD1_k127_157796_30 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
HKD1_k127_157796_31 Pfam Binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 375.0
HKD1_k127_157796_32 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 368.0
HKD1_k127_157796_33 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 359.0
HKD1_k127_157796_34 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 349.0
HKD1_k127_157796_35 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 346.0
HKD1_k127_157796_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 359.0
HKD1_k127_157796_37 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
HKD1_k127_157796_38 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 338.0
HKD1_k127_157796_39 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 314.0
HKD1_k127_157796_4 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 3.91e-250 776.0
HKD1_k127_157796_40 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 303.0
HKD1_k127_157796_41 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 302.0
HKD1_k127_157796_42 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001728 295.0
HKD1_k127_157796_43 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
HKD1_k127_157796_44 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000299 287.0
HKD1_k127_157796_45 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003141 280.0
HKD1_k127_157796_46 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000256 274.0
HKD1_k127_157796_47 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002256 284.0
HKD1_k127_157796_48 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000005236 264.0
HKD1_k127_157796_49 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005909 268.0
HKD1_k127_157796_5 Isocitrate lyase K01637 - 4.1.3.1 2.64e-231 722.0
HKD1_k127_157796_50 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002712 267.0
HKD1_k127_157796_51 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009738 239.0
HKD1_k127_157796_52 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000543 242.0
HKD1_k127_157796_53 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000001024 239.0
HKD1_k127_157796_54 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007434 221.0
HKD1_k127_157796_55 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000054 212.0
HKD1_k127_157796_56 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000007551 205.0
HKD1_k127_157796_57 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000005607 205.0
HKD1_k127_157796_58 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000001143 200.0
HKD1_k127_157796_59 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000004957 195.0
HKD1_k127_157796_6 Methyl-accepting chemotaxis protein K02660 - - 3.176e-223 712.0
HKD1_k127_157796_60 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000924 196.0
HKD1_k127_157796_61 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000004821 190.0
HKD1_k127_157796_62 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000006451 181.0
HKD1_k127_157796_63 - - - - 0.0000000000000000000000000000000000000000000000001457 187.0
HKD1_k127_157796_64 - - - - 0.000000000000000000000000000000000000000000000001527 183.0
HKD1_k127_157796_65 Tim44 - - - 0.0000000000000000000000000000000000000000000000625 179.0
HKD1_k127_157796_66 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000208 171.0
HKD1_k127_157796_67 integral membrane protein K02221 - - 0.000000000000000000000000000000000000000000002421 171.0
HKD1_k127_157796_68 Rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000003553 172.0
HKD1_k127_157796_69 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000003352 168.0
HKD1_k127_157796_7 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.539e-216 689.0
HKD1_k127_157796_70 HIT domain - - - 0.0000000000000000000000000000000000000000005612 161.0
HKD1_k127_157796_71 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000000000007967 162.0
HKD1_k127_157796_72 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000000000000000000000001386 165.0
HKD1_k127_157796_73 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000261 155.0
HKD1_k127_157796_74 Chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000000000000002723 146.0
HKD1_k127_157796_75 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000001503 143.0
HKD1_k127_157796_76 Redoxin family - - - 0.0000000000000000000000000000000001222 139.0
HKD1_k127_157796_77 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000003977 135.0
HKD1_k127_157796_78 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000002309 124.0
HKD1_k127_157796_79 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000001571 123.0
HKD1_k127_157796_8 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 5.446e-214 699.0
HKD1_k127_157796_80 Belongs to the UPF0250 family K09158 - - 0.000000000000000000000000003002 118.0
HKD1_k127_157796_81 Protein of unknown function (DUF1161) - - - 0.00000000000000000002101 93.0
HKD1_k127_157796_82 Membrane fusogenic activity K09806 - - 0.0000000000000001354 83.0
HKD1_k127_157796_83 Protein of unknown function (DUF2782) - - - 0.0000000000000006298 84.0
HKD1_k127_157796_84 DUF167 K09131 - - 0.000000000000001298 83.0
HKD1_k127_157796_9 twitching motility protein K02670 - - 2.352e-204 642.0
HKD1_k127_1605768_0 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 521.0
HKD1_k127_1605768_1 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000003611 126.0
HKD1_k127_1605768_2 rhodanese-related sulfurtransferase - - - 0.000000000000000000000003515 107.0
HKD1_k127_166781_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.837e-250 780.0
HKD1_k127_166781_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.872e-242 754.0
HKD1_k127_166781_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 531.0
HKD1_k127_166781_11 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 527.0
HKD1_k127_166781_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 516.0
HKD1_k127_166781_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 513.0
HKD1_k127_166781_14 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 496.0
HKD1_k127_166781_15 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 452.0
HKD1_k127_166781_16 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 435.0
HKD1_k127_166781_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 359.0
HKD1_k127_166781_18 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 353.0
HKD1_k127_166781_19 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 350.0
HKD1_k127_166781_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.501e-224 709.0
HKD1_k127_166781_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 357.0
HKD1_k127_166781_21 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 347.0
HKD1_k127_166781_22 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 340.0
HKD1_k127_166781_23 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 327.0
HKD1_k127_166781_24 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 317.0
HKD1_k127_166781_25 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 321.0
HKD1_k127_166781_26 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 319.0
HKD1_k127_166781_27 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 316.0
HKD1_k127_166781_28 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 315.0
HKD1_k127_166781_29 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 291.0
HKD1_k127_166781_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.759e-221 691.0
HKD1_k127_166781_30 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001289 277.0
HKD1_k127_166781_31 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002888 286.0
HKD1_k127_166781_32 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 267.0
HKD1_k127_166781_33 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000005178 262.0
HKD1_k127_166781_34 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000002148 267.0
HKD1_k127_166781_35 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000007489 260.0
HKD1_k127_166781_36 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006727 261.0
HKD1_k127_166781_37 type 4 pilus biogenesis protein K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002338 247.0
HKD1_k127_166781_38 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001509 238.0
HKD1_k127_166781_39 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000006211 238.0
HKD1_k127_166781_4 Thiolase, C-terminal domain - - - 2.987e-206 648.0
HKD1_k127_166781_40 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000001566 218.0
HKD1_k127_166781_41 KR domain - - - 0.0000000000000000000000000000000000000000000000000000001672 213.0
HKD1_k127_166781_42 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000007705 199.0
HKD1_k127_166781_43 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000004102 160.0
HKD1_k127_166781_44 Helix-turn-helix domain K15539 - - 0.00000000000000000000000000000000000000009371 163.0
HKD1_k127_166781_45 - - - - 0.000000000000000000000000000000000004498 144.0
HKD1_k127_166781_46 Cupredoxin-like domain - - - 0.000000000000000000000000000000003705 131.0
HKD1_k127_166781_47 Psort location CytoplasmicMembrane, score K03558 - - 0.00000000000000000000000000000001117 133.0
HKD1_k127_166781_48 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000001759 131.0
HKD1_k127_166781_49 dehydratase - - - 0.0000000000000000000000000196 114.0
HKD1_k127_166781_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 614.0
HKD1_k127_166781_50 Belongs to the ompA family K03640 - - 0.00000000000000000000000002805 109.0
HKD1_k127_166781_51 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000005476 106.0
HKD1_k127_166781_52 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.000000000000000000002207 96.0
HKD1_k127_166781_53 Sporulation related domain - - - 0.000000000000000000004634 100.0
HKD1_k127_166781_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 572.0
HKD1_k127_166781_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 553.0
HKD1_k127_166781_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 546.0
HKD1_k127_166781_9 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 538.0
HKD1_k127_1735227_0 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 456.0
HKD1_k127_1735227_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 434.0
HKD1_k127_1735227_2 carbohydrate phosphatase activity K01086 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 401.0
HKD1_k127_1735227_3 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004555 265.0
HKD1_k127_1735227_4 subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000001825 230.0
HKD1_k127_1735227_5 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000001403 225.0
HKD1_k127_178433_0 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 529.0
HKD1_k127_178433_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 379.0
HKD1_k127_178433_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000004621 128.0
HKD1_k127_178433_3 Resolvase, N terminal domain - - - 0.0000000000000000000000000000001527 128.0
HKD1_k127_178433_5 ATPases associated with a variety of cellular activities - - - 0.000002417 53.0
HKD1_k127_188299_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.515e-207 668.0
HKD1_k127_188299_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 481.0
HKD1_k127_188299_2 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 466.0
HKD1_k127_188299_3 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 429.0
HKD1_k127_188299_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 428.0
HKD1_k127_188299_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 379.0
HKD1_k127_188299_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000005091 204.0
HKD1_k127_188299_7 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000001735 170.0
HKD1_k127_188299_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000004137 98.0
HKD1_k127_1886106_0 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 358.0
HKD1_k127_1886106_1 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000001301 203.0
HKD1_k127_1886106_2 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000002032 184.0
HKD1_k127_1886106_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0001499 45.0
HKD1_k127_192768_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 587.0
HKD1_k127_192768_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 570.0
HKD1_k127_192768_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 477.0
HKD1_k127_192768_3 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 425.0
HKD1_k127_192768_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 416.0
HKD1_k127_192768_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 311.0
HKD1_k127_192768_6 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000000012 201.0
HKD1_k127_194154_0 Diguanylate cyclase - - - 4.537e-202 661.0
HKD1_k127_194154_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 593.0
HKD1_k127_194154_2 Domain of unknown function (DUF374) - - - 0.000000000000000000000000000000000000000000001538 174.0
HKD1_k127_194154_3 PFAM Lysine exporter protein (LYSE YGGA) K06895 - - 0.00000000000000000003964 93.0
HKD1_k127_194154_4 hydratase K02554 - 4.2.1.80 0.0000000001319 74.0
HKD1_k127_194154_5 Protein conserved in bacteria - - - 0.0006973 45.0
HKD1_k127_194154_6 Belongs to the P-Pant transferase superfamily K06133 - - 0.0009444 49.0
HKD1_k127_1950722_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 524.0
HKD1_k127_1950722_1 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 467.0
HKD1_k127_1950722_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 319.0
HKD1_k127_1950722_3 TolA binding protein trimerisation - - - 0.000000000000000000000000000000000000000000000000000005057 199.0
HKD1_k127_1950722_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000004059 189.0
HKD1_k127_1954523_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 8.785e-250 782.0
HKD1_k127_1954523_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 9.362e-212 667.0
HKD1_k127_1954523_2 TIGRFAM malate synthase A K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 589.0
HKD1_k127_1954523_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 488.0
HKD1_k127_1954523_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 428.0
HKD1_k127_1954523_5 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 408.0
HKD1_k127_1954523_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 344.0
HKD1_k127_1954523_7 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000002477 197.0
HKD1_k127_1954523_8 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000307 150.0
HKD1_k127_1954523_9 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000777 112.0
HKD1_k127_1976408_0 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 493.0
HKD1_k127_1976408_1 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000003197 179.0
HKD1_k127_1976408_2 Haem-degrading - - - 0.0000000000000000000000000000000000000000000001671 181.0
HKD1_k127_2004590_0 Acyl-CoA dehydrogenase N terminal K20035 - - 1.344e-252 792.0
HKD1_k127_2004590_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.412e-237 745.0
HKD1_k127_2004590_10 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 453.0
HKD1_k127_2004590_11 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 445.0
HKD1_k127_2004590_12 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 436.0
HKD1_k127_2004590_13 Electron transfer flavoprotein, beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 395.0
HKD1_k127_2004590_14 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 341.0
HKD1_k127_2004590_15 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 301.0
HKD1_k127_2004590_16 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 282.0
HKD1_k127_2004590_17 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000002221 283.0
HKD1_k127_2004590_18 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000009615 232.0
HKD1_k127_2004590_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
HKD1_k127_2004590_2 Voltage gated chloride channel - - - 4.139e-231 721.0
HKD1_k127_2004590_20 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000000000000652 188.0
HKD1_k127_2004590_21 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000009582 179.0
HKD1_k127_2004590_22 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000002344 141.0
HKD1_k127_2004590_23 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000007669 139.0
HKD1_k127_2004590_24 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000138 116.0
HKD1_k127_2004590_25 EamA-like transporter family - - - 0.0000000000000000000001498 109.0
HKD1_k127_2004590_26 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000007158 74.0
HKD1_k127_2004590_27 Methyl-transferase K06983 - - 0.0000000000008664 69.0
HKD1_k127_2004590_3 Tripartite tricarboxylate transporter TctA family - - - 6.804e-221 694.0
HKD1_k127_2004590_4 PFAM carboxyl transferase - - - 2.253e-213 674.0
HKD1_k127_2004590_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 9.093e-205 641.0
HKD1_k127_2004590_6 PFAM Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 579.0
HKD1_k127_2004590_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 555.0
HKD1_k127_2004590_8 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 559.0
HKD1_k127_2004590_9 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 509.0
HKD1_k127_2025105_0 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 483.0
HKD1_k127_2025105_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 437.0
HKD1_k127_2025105_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 396.0
HKD1_k127_2025105_3 response regulator, receiver K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 292.0
HKD1_k127_2025105_4 Eukaryotic integral membrane protein (DUF1751) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002032 246.0
HKD1_k127_2025105_5 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000000007605 217.0
HKD1_k127_2025105_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000003524 81.0
HKD1_k127_2028564_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.179e-255 794.0
HKD1_k127_2028564_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 428.0
HKD1_k127_2028564_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 375.0
HKD1_k127_2028564_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000001257 169.0
HKD1_k127_2028564_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000008206 117.0
HKD1_k127_2031864_0 Bifunctional transglycosylase second domain K05365 - 2.4.1.129,3.4.16.4 5.009e-273 859.0
HKD1_k127_2031864_1 Sugar (and other) transporter - - - 1.942e-255 798.0
HKD1_k127_2031864_10 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 486.0
HKD1_k127_2031864_11 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 469.0
HKD1_k127_2031864_12 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 439.0
HKD1_k127_2031864_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 442.0
HKD1_k127_2031864_14 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 423.0
HKD1_k127_2031864_15 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 398.0
HKD1_k127_2031864_16 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 384.0
HKD1_k127_2031864_17 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 377.0
HKD1_k127_2031864_18 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 358.0
HKD1_k127_2031864_19 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 374.0
HKD1_k127_2031864_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 605.0
HKD1_k127_2031864_20 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 328.0
HKD1_k127_2031864_21 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 335.0
HKD1_k127_2031864_22 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 308.0
HKD1_k127_2031864_23 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 299.0
HKD1_k127_2031864_24 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 291.0
HKD1_k127_2031864_25 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 287.0
HKD1_k127_2031864_26 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003745 278.0
HKD1_k127_2031864_27 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005998 285.0
HKD1_k127_2031864_28 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000637 263.0
HKD1_k127_2031864_29 PFAM Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008457 261.0
HKD1_k127_2031864_3 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 578.0
HKD1_k127_2031864_30 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000007782 227.0
HKD1_k127_2031864_31 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000003346 222.0
HKD1_k127_2031864_32 TIGRFAM exopolysaccharide biosynthesis operon protein EpsL - - - 0.0000000000000000000000000000000000000000000000000000000001582 220.0
HKD1_k127_2031864_33 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000001935 179.0
HKD1_k127_2031864_34 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000003429 191.0
HKD1_k127_2031864_35 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000002831 166.0
HKD1_k127_2031864_36 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000002478 173.0
HKD1_k127_2031864_37 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000005642 164.0
HKD1_k127_2031864_38 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000007991 160.0
HKD1_k127_2031864_39 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000008107 147.0
HKD1_k127_2031864_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 559.0
HKD1_k127_2031864_40 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000266 124.0
HKD1_k127_2031864_41 Tetratricopeptide repeat - - - 0.0000000000000000000000002831 110.0
HKD1_k127_2031864_42 Transcription regulator that can specifically activate or repress expression of target genes K06075 - - 0.00000000000000000000006199 104.0
HKD1_k127_2031864_43 Iron-binding zinc finger CDGSH type K05710 - - 0.000000000000000008087 87.0
HKD1_k127_2031864_5 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 548.0
HKD1_k127_2031864_6 major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 548.0
HKD1_k127_2031864_7 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 539.0
HKD1_k127_2031864_8 Major Facilitator Superfamily K08169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 520.0
HKD1_k127_2031864_9 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 503.0
HKD1_k127_2046950_0 Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate K01955 - 6.3.5.5 0.0 1491.0
HKD1_k127_2046950_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1068.0
HKD1_k127_2046950_10 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.0000000000000000000000000000000000000000000000000000000003021 213.0
HKD1_k127_2046950_11 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000000000000000000000000000000000000000000000000323 209.0
HKD1_k127_2046950_12 Cytochrome c K08738 - - 0.0000000000000000000000000000007836 125.0
HKD1_k127_2046950_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 622.0
HKD1_k127_2046950_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 482.0
HKD1_k127_2046950_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
HKD1_k127_2046950_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 427.0
HKD1_k127_2046950_6 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 422.0
HKD1_k127_2046950_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 324.0
HKD1_k127_2046950_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009002 253.0
HKD1_k127_2046950_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000002645 219.0
HKD1_k127_206348_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1431.0
HKD1_k127_206348_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 - 2.1.3.3,2.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 606.0
HKD1_k127_206348_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 586.0
HKD1_k127_206348_3 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 492.0
HKD1_k127_206348_4 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 462.0
HKD1_k127_206348_5 Arginine K01478 - 3.5.3.6 0.0000000000000000000000000000000271 125.0
HKD1_k127_206348_6 - - - - 0.0000000000000000000009599 100.0
HKD1_k127_206348_7 Phospholipid methyltransferase - - - 0.000000000000001799 89.0
HKD1_k127_2093572_0 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 563.0
HKD1_k127_2093572_1 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 505.0
HKD1_k127_2093572_2 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 421.0
HKD1_k127_2093572_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 347.0
HKD1_k127_2093572_4 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 310.0
HKD1_k127_2093572_5 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000000000482 128.0
HKD1_k127_2093572_6 Bacterial dnaA protein - - - 0.0000000000000821 74.0
HKD1_k127_2096731_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.695e-281 872.0
HKD1_k127_2096731_1 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 2.27e-210 663.0
HKD1_k127_2096731_10 PFAM response regulator receiver K11443 - - 0.00000000000000000000000000000009363 133.0
HKD1_k127_2096731_2 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 524.0
HKD1_k127_2096731_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 497.0
HKD1_k127_2096731_4 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 448.0
HKD1_k127_2096731_5 Dehydrogenase E1 component K11381,K21416 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 440.0
HKD1_k127_2096731_6 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 396.0
HKD1_k127_2096731_7 transport system periplasmic component K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 340.0
HKD1_k127_2096731_8 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000008786 221.0
HKD1_k127_2096731_9 SMART cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000006428 200.0
HKD1_k127_2096797_0 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 420.0
HKD1_k127_2096797_1 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 349.0
HKD1_k127_2096797_2 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 332.0
HKD1_k127_2096797_3 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000001359 207.0
HKD1_k127_2096797_4 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000004317 172.0
HKD1_k127_2096797_5 Chalcone isomerase-like - - - 0.000000000000000000000000000000000003755 147.0
HKD1_k127_2116201_0 Apolipoprotein A1/A4/E domain - - - 1.753e-265 863.0
HKD1_k127_2116201_1 Histidine kinase K07647 - 2.7.13.3 0.000000000000003364 81.0
HKD1_k127_2121151_0 Fumarate reductase flavoprotein C-term - - - 7.938e-220 696.0
HKD1_k127_2121151_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 376.0
HKD1_k127_2121151_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000002239 166.0
HKD1_k127_2121151_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000002657 177.0
HKD1_k127_2121151_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000008121 129.0
HKD1_k127_2121264_0 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000005157 179.0
HKD1_k127_2121264_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000002731 168.0
HKD1_k127_2121264_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000009002 121.0
HKD1_k127_2121264_3 Phage integrase family - - - 0.000000000000000000000002737 105.0
HKD1_k127_2121264_4 Winged helix DNA-binding domain - - - 0.0000000000002814 71.0
HKD1_k127_2121264_5 - - - - 0.000000009497 59.0
HKD1_k127_2121264_6 Belongs to the 'phage' integrase family - - - 0.00000003899 57.0
HKD1_k127_2121264_7 Type IV secretory pathway VirD2 - - - 0.00008333 51.0
HKD1_k127_2121331_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1587.0
HKD1_k127_2121331_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.71e-284 891.0
HKD1_k127_2121331_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 366.0
HKD1_k127_2121331_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 353.0
HKD1_k127_2121331_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 338.0
HKD1_k127_2121331_13 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 332.0
HKD1_k127_2121331_14 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 335.0
HKD1_k127_2121331_15 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 342.0
HKD1_k127_2121331_16 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 319.0
HKD1_k127_2121331_17 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 287.0
HKD1_k127_2121331_18 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004349 289.0
HKD1_k127_2121331_19 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
HKD1_k127_2121331_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 2.678e-249 785.0
HKD1_k127_2121331_20 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009065 270.0
HKD1_k127_2121331_21 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002116 284.0
HKD1_k127_2121331_22 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000001616 271.0
HKD1_k127_2121331_23 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008129 258.0
HKD1_k127_2121331_24 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005809 263.0
HKD1_k127_2121331_25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003443 260.0
HKD1_k127_2121331_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004407 247.0
HKD1_k127_2121331_27 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001722 245.0
HKD1_k127_2121331_28 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000004105 213.0
HKD1_k127_2121331_29 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000009676 158.0
HKD1_k127_2121331_3 Participates in both transcription termination and antitermination K02600 - - 5.945e-229 718.0
HKD1_k127_2121331_30 cheY-homologous receiver domain - - - 0.00000000000000000000000000000006228 135.0
HKD1_k127_2121331_4 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.645e-212 664.0
HKD1_k127_2121331_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 576.0
HKD1_k127_2121331_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 580.0
HKD1_k127_2121331_7 D-amino acid dehydrogenase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 486.0
HKD1_k127_2121331_8 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 457.0
HKD1_k127_2121331_9 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 408.0
HKD1_k127_2133958_0 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 325.0
HKD1_k127_2133958_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000001994 160.0
HKD1_k127_2133958_2 Acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000002246 138.0
HKD1_k127_2133958_3 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000112 134.0
HKD1_k127_2133958_4 TonB C terminal K03646 - - 0.000000000000000001521 89.0
HKD1_k127_2140274_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2271.0
HKD1_k127_2140274_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2188.0
HKD1_k127_2140274_10 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 279.0
HKD1_k127_2140274_11 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002366 254.0
HKD1_k127_2140274_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001011 252.0
HKD1_k127_2140274_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001327 262.0
HKD1_k127_2140274_14 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000004285 245.0
HKD1_k127_2140274_15 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000004146 238.0
HKD1_k127_2140274_16 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000006195 218.0
HKD1_k127_2140274_17 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000016 168.0
HKD1_k127_2140274_18 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000002561 147.0
HKD1_k127_2140274_19 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000007325 130.0
HKD1_k127_2140274_2 chloride channel K03281 - - 4.099e-204 662.0
HKD1_k127_2140274_20 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.0000000000000000000000000003712 117.0
HKD1_k127_2140274_21 membrane transporter protein K07090 - - 0.000000000000000002562 94.0
HKD1_k127_2140274_22 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000001999 76.0
HKD1_k127_2140274_23 lipoprotein - - - 0.0000000002872 68.0
HKD1_k127_2140274_24 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000002137 51.0
HKD1_k127_2140274_3 Transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 532.0
HKD1_k127_2140274_4 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 488.0
HKD1_k127_2140274_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 452.0
HKD1_k127_2140274_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 402.0
HKD1_k127_2140274_7 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 335.0
HKD1_k127_2140274_8 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 323.0
HKD1_k127_2140274_9 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 324.0
HKD1_k127_2151289_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 362.0
HKD1_k127_2151289_1 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000001353 154.0
HKD1_k127_2171862_0 ABC transporter - - - 1.102e-230 742.0
HKD1_k127_2171862_1 PFAM secretion protein HlyD family protein K01993,K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 402.0
HKD1_k127_2171862_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005101 267.0
HKD1_k127_2171862_3 membrane - - - 0.0000000000000000000000001931 113.0
HKD1_k127_2185803_0 Glucodextranase, domain N K01178 - 3.2.1.3 2.162e-294 919.0
HKD1_k127_2185803_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 319.0
HKD1_k127_2185803_2 LysR substrate binding domain - - - 0.000002905 53.0
HKD1_k127_220845_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1038.0
HKD1_k127_220845_1 C oxidoreductase subunit A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 470.0
HKD1_k127_220845_2 Cytochrome c - - - 0.000000000000007875 79.0
HKD1_k127_2212992_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1019.0
HKD1_k127_2212992_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 5.17e-310 972.0
HKD1_k127_2212992_10 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 319.0
HKD1_k127_2212992_11 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000007666 228.0
HKD1_k127_2212992_12 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000003379 195.0
HKD1_k127_2212992_13 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000211 154.0
HKD1_k127_2212992_14 - - - - 0.0000000000000005396 86.0
HKD1_k127_2212992_2 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 591.0
HKD1_k127_2212992_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 565.0
HKD1_k127_2212992_4 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 560.0
HKD1_k127_2212992_5 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 511.0
HKD1_k127_2212992_6 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 424.0
HKD1_k127_2212992_7 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 423.0
HKD1_k127_2212992_8 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 384.0
HKD1_k127_2212992_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 329.0
HKD1_k127_225074_0 Heat shock 70 kDa protein K04043 - - 9.103e-259 801.0
HKD1_k127_225074_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 589.0
HKD1_k127_225074_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000004073 108.0
HKD1_k127_225074_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 512.0
HKD1_k127_225074_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 473.0
HKD1_k127_225074_4 Ferrochelatase K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 403.0
HKD1_k127_225074_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 347.0
HKD1_k127_225074_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 314.0
HKD1_k127_225074_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000002925 214.0
HKD1_k127_225074_8 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000007789 183.0
HKD1_k127_225074_9 GrpE K03687 - - 0.0000000000000000000000000000000000000141 151.0
HKD1_k127_2267730_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 5.605e-203 640.0
HKD1_k127_2267730_1 PFAM class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000000000008338 193.0
HKD1_k127_2286733_0 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
HKD1_k127_2286733_1 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002485 237.0
HKD1_k127_2286733_2 - - - - 0.00000000000000000000000000000000000000000000000000001427 196.0
HKD1_k127_2286733_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000000000000000000000000000000000000000000000000002298 196.0
HKD1_k127_2286733_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000007146 179.0
HKD1_k127_2314326_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.157e-239 746.0
HKD1_k127_2314326_1 Transport of potassium into the cell K03549 - - 3.398e-212 676.0
HKD1_k127_2314326_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000005235 256.0
HKD1_k127_2314326_11 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000008102 216.0
HKD1_k127_2314326_12 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000001132 217.0
HKD1_k127_2314326_13 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000002339 193.0
HKD1_k127_2314326_14 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000001247 189.0
HKD1_k127_2314326_15 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000005489 159.0
HKD1_k127_2314326_16 PFAM ribosomal protein L31 K02909 - - 0.0000000000000000000000000002262 117.0
HKD1_k127_2314326_17 - - - - 0.00000000000000000000001214 106.0
HKD1_k127_2314326_18 Putative prokaryotic signal transducing protein - - - 0.0000000000000007052 90.0
HKD1_k127_2314326_19 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000008495 84.0
HKD1_k127_2314326_2 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 607.0
HKD1_k127_2314326_20 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000002891 75.0
HKD1_k127_2314326_21 - - - - 0.0000000351 58.0
HKD1_k127_2314326_3 Zn-dependent protease with chaperone function K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 513.0
HKD1_k127_2314326_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 477.0
HKD1_k127_2314326_5 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 475.0
HKD1_k127_2314326_6 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 430.0
HKD1_k127_2314326_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 343.0
HKD1_k127_2314326_8 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 282.0
HKD1_k127_2314326_9 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001863 271.0
HKD1_k127_2314729_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 4.679e-304 970.0
HKD1_k127_2314729_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.266e-264 838.0
HKD1_k127_2314729_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 309.0
HKD1_k127_2314729_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 295.0
HKD1_k127_2314729_12 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 285.0
HKD1_k127_2314729_13 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001275 270.0
HKD1_k127_2314729_14 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001625 266.0
HKD1_k127_2314729_15 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000161 239.0
HKD1_k127_2314729_16 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000045 250.0
HKD1_k127_2314729_17 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000004761 258.0
HKD1_k127_2314729_18 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000008612 225.0
HKD1_k127_2314729_19 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000000000000009082 181.0
HKD1_k127_2314729_2 Competence protein ComEC Rec2 K02238 - - 2.016e-212 683.0
HKD1_k127_2314729_20 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000002574 183.0
HKD1_k127_2314729_21 homoserine transmembrane transporter activity K03329 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000009866 178.0
HKD1_k127_2314729_22 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000002069 164.0
HKD1_k127_2314729_23 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000007007 158.0
HKD1_k127_2314729_24 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000001939 148.0
HKD1_k127_2314729_25 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000002888 149.0
HKD1_k127_2314729_26 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000009322 130.0
HKD1_k127_2314729_27 coenzyme F420 binding K07226 - - 0.00000000000000000000000001023 116.0
HKD1_k127_2314729_3 Major facilitator superfamily K03446 - - 1.016e-196 644.0
HKD1_k127_2314729_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 542.0
HKD1_k127_2314729_5 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 534.0
HKD1_k127_2314729_6 Aminotransferase class I and II K09758 - 4.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 491.0
HKD1_k127_2314729_7 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 443.0
HKD1_k127_2314729_8 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 414.0
HKD1_k127_2314729_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 366.0
HKD1_k127_2321423_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 5.612e-232 740.0
HKD1_k127_2321423_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 501.0
HKD1_k127_2321423_2 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 404.0
HKD1_k127_2321423_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 351.0
HKD1_k127_2321423_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 299.0
HKD1_k127_2321423_5 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000321 257.0
HKD1_k127_2321423_6 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000155 180.0
HKD1_k127_2321423_7 LemA family - - - 0.0000000000000000000000000000000000000000007154 174.0
HKD1_k127_2326040_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1134.0
HKD1_k127_2326040_1 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 2.856e-219 696.0
HKD1_k127_2326040_10 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
HKD1_k127_2326040_11 Belongs to the bacterial solute-binding protein 3 family K01713 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 340.0
HKD1_k127_2326040_12 Beta-lactamase K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 342.0
HKD1_k127_2326040_13 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 348.0
HKD1_k127_2326040_14 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 343.0
HKD1_k127_2326040_15 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 316.0
HKD1_k127_2326040_16 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 313.0
HKD1_k127_2326040_17 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 328.0
HKD1_k127_2326040_18 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 329.0
HKD1_k127_2326040_19 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 309.0
HKD1_k127_2326040_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 500.0
HKD1_k127_2326040_20 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000631 271.0
HKD1_k127_2326040_21 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 255.0
HKD1_k127_2326040_22 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001242 259.0
HKD1_k127_2326040_23 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000002033 253.0
HKD1_k127_2326040_24 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003633 247.0
HKD1_k127_2326040_25 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000004556 211.0
HKD1_k127_2326040_26 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000003606 181.0
HKD1_k127_2326040_27 Dehydroquinase class II - - - 0.00000000000000000000000000000000000000000000003136 174.0
HKD1_k127_2326040_28 - - - - 0.0000000000000000000000000000000000000001355 158.0
HKD1_k127_2326040_29 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000000003519 136.0
HKD1_k127_2326040_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 472.0
HKD1_k127_2326040_30 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000002571 142.0
HKD1_k127_2326040_31 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000004547 119.0
HKD1_k127_2326040_32 - - - - 0.0000000000000000000000001059 117.0
HKD1_k127_2326040_33 protein conserved in bacteria - - - 0.00001716 56.0
HKD1_k127_2326040_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 446.0
HKD1_k127_2326040_5 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 432.0
HKD1_k127_2326040_6 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 415.0
HKD1_k127_2326040_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 403.0
HKD1_k127_2326040_8 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 365.0
HKD1_k127_2326040_9 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 357.0
HKD1_k127_2336059_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 444.0
HKD1_k127_2336059_1 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 387.0
HKD1_k127_2336059_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 367.0
HKD1_k127_2336059_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000015 175.0
HKD1_k127_2336059_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000001582 93.0
HKD1_k127_2336059_5 - - - - 0.00000000000006352 76.0
HKD1_k127_2336059_6 methyltransferase activity K21310 - 2.1.1.334 0.000000000549 60.0
HKD1_k127_2339520_0 Alpha-2-Macroglobulin K06894 - - 0.0 1329.0
HKD1_k127_2339520_1 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.000000000000000000006651 96.0
HKD1_k127_2353326_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.073e-269 838.0
HKD1_k127_2353326_1 Peptidase family M41 K03798 - - 9.041e-254 796.0
HKD1_k127_2353326_10 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000009518 142.0
HKD1_k127_2353326_11 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000004125 120.0
HKD1_k127_2353326_12 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000002213 124.0
HKD1_k127_2353326_13 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000009551 104.0
HKD1_k127_2353326_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 471.0
HKD1_k127_2353326_3 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 466.0
HKD1_k127_2353326_4 Polycystin cation channel K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 301.0
HKD1_k127_2353326_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000111 224.0
HKD1_k127_2353326_6 Bacterial regulatory helix-turn-helix protein, lysR family K03717 - - 0.0000000000000000000000000000000000000000000000000000000000003048 217.0
HKD1_k127_2353326_7 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000003443 206.0
HKD1_k127_2353326_8 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000000000001119 158.0
HKD1_k127_2353326_9 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000000001685 167.0
HKD1_k127_2353580_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 474.0
HKD1_k127_2353580_1 PFAM MaoC like domain - - - 0.00000000000000000000000000000000000000002274 155.0
HKD1_k127_2365252_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.215e-244 762.0
HKD1_k127_2365252_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.791e-242 755.0
HKD1_k127_2365252_10 Enoyl-CoA hydratase K15513 - 4.1.2.44 0.0000000000000000304 81.0
HKD1_k127_2365252_11 Catalyzes the conversion of ferulic acid to feruloyl-CoA K12508 - 6.2.1.34 0.000000000001784 69.0
HKD1_k127_2365252_12 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000004918 70.0
HKD1_k127_2365252_2 Receptor family ligand binding region K01999 - - 7.832e-203 641.0
HKD1_k127_2365252_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 613.0
HKD1_k127_2365252_4 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 566.0
HKD1_k127_2365252_5 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 487.0
HKD1_k127_2365252_6 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 479.0
HKD1_k127_2365252_7 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 376.0
HKD1_k127_2365252_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 379.0
HKD1_k127_2365252_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 360.0
HKD1_k127_23720_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 327.0
HKD1_k127_23720_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006501 254.0
HKD1_k127_23720_10 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000004875 142.0
HKD1_k127_23720_11 - - - - 0.00000000000000000000000000007908 131.0
HKD1_k127_23720_12 - - - - 0.0000000000000000000000002051 113.0
HKD1_k127_23720_13 - - - - 0.0000000000000000000000003445 115.0
HKD1_k127_23720_15 Acetyltransferase (GNAT) domain - - - 0.000000000000001103 91.0
HKD1_k127_23720_2 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000004333 229.0
HKD1_k127_23720_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000001696 218.0
HKD1_k127_23720_4 - - - - 0.00000000000000000000000000000000000000000000000000001942 198.0
HKD1_k127_23720_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000001988 194.0
HKD1_k127_23720_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000006631 194.0
HKD1_k127_23720_7 phosphonoacetaldehyde hydrolase activity K00817,K01560,K07025,K20866 - 2.6.1.9,3.1.3.10,3.8.1.2 0.000000000000000000000000000000000000000000000002955 180.0
HKD1_k127_23720_8 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000001354 156.0
HKD1_k127_23720_9 Carboxylesterase family - - - 0.0000000000000000000000000000000000000001415 161.0
HKD1_k127_2388297_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1242.0
HKD1_k127_2388297_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1096.0
HKD1_k127_2388297_10 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 421.0
HKD1_k127_2388297_11 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 402.0
HKD1_k127_2388297_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 398.0
HKD1_k127_2388297_13 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 380.0
HKD1_k127_2388297_14 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 359.0
HKD1_k127_2388297_15 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 337.0
HKD1_k127_2388297_16 RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 336.0
HKD1_k127_2388297_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 319.0
HKD1_k127_2388297_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 310.0
HKD1_k127_2388297_19 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 315.0
HKD1_k127_2388297_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.341e-304 948.0
HKD1_k127_2388297_20 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 297.0
HKD1_k127_2388297_21 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 299.0
HKD1_k127_2388297_22 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001539 286.0
HKD1_k127_2388297_23 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 250.0
HKD1_k127_2388297_24 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
HKD1_k127_2388297_25 PFAM SmpA OmlA - - - 0.00000000000000000000000000000000000000000000000000000007664 199.0
HKD1_k127_2388297_26 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000006075 200.0
HKD1_k127_2388297_27 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000006085 193.0
HKD1_k127_2388297_28 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000891 186.0
HKD1_k127_2388297_29 Ubiquinol-cytochrome C chaperone K17662 - - 0.0000000000000000000000000000000000000000000000008521 180.0
HKD1_k127_2388297_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 7.199e-242 753.0
HKD1_k127_2388297_30 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000006464 166.0
HKD1_k127_2388297_31 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000007019 164.0
HKD1_k127_2388297_32 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000002628 143.0
HKD1_k127_2388297_33 - - - - 0.00000000000000000000000000001159 125.0
HKD1_k127_2388297_34 Protein of unknown function (DUF2905) - - - 0.000000000000000000000001506 105.0
HKD1_k127_2388297_35 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000002182 102.0
HKD1_k127_2388297_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 573.0
HKD1_k127_2388297_5 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 539.0
HKD1_k127_2388297_6 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 517.0
HKD1_k127_2388297_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 491.0
HKD1_k127_2388297_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 457.0
HKD1_k127_2388297_9 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 456.0
HKD1_k127_2395000_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 471.0
HKD1_k127_2395000_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 307.0
HKD1_k127_2395000_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000001988 201.0
HKD1_k127_2395000_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000001645 160.0
HKD1_k127_2395000_4 lactoylglutathione lyase activity K08234 - - 0.000002831 59.0
HKD1_k127_2396561_0 CoA-transferase family III - - - 2.371e-202 633.0
HKD1_k127_2396561_1 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 584.0
HKD1_k127_2396561_2 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 450.0
HKD1_k127_2448162_0 - - - - 0.000000000000000000000000000000000000000000000000000000003625 212.0
HKD1_k127_2448162_1 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000002012 179.0
HKD1_k127_2448162_2 Cas6 Crispr - - - 0.000000000000000000000000002065 121.0
HKD1_k127_2448162_3 - - - - 0.0000000000000000000008682 98.0
HKD1_k127_2460578_0 DNA helicase K03657 - 3.6.4.12 5.574e-288 898.0
HKD1_k127_2460578_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 3.244e-247 773.0
HKD1_k127_2460578_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009644 277.0
HKD1_k127_2460578_3 - - - - 0.0000000000000000000000000000000000000000002611 164.0
HKD1_k127_2473144_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1428.0
HKD1_k127_2473144_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.203e-288 894.0
HKD1_k127_2473144_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 330.0
HKD1_k127_2473144_11 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 329.0
HKD1_k127_2473144_12 PFAM Glutamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 276.0
HKD1_k127_2473144_13 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002492 248.0
HKD1_k127_2473144_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000006389 226.0
HKD1_k127_2473144_15 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000000000002147 231.0
HKD1_k127_2473144_16 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000001238 162.0
HKD1_k127_2473144_17 OsmC-like protein - - - 0.0000000000000000000000000000000000000001854 156.0
HKD1_k127_2473144_18 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000004778 136.0
HKD1_k127_2473144_19 - - - - 0.0000000000000000000000001506 120.0
HKD1_k127_2473144_2 24 kD subunit K00122 - 1.17.1.9 7.862e-265 828.0
HKD1_k127_2473144_20 cyclic nucleotide-binding - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000005712 64.0
HKD1_k127_2473144_21 cyclic nucleotide-binding - - - 0.00000922 57.0
HKD1_k127_2473144_3 Tripartite tricarboxylate transporter TctA family K07793 - - 2.522e-236 738.0
HKD1_k127_2473144_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.699e-218 688.0
HKD1_k127_2473144_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.015e-194 617.0
HKD1_k127_2473144_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 511.0
HKD1_k127_2473144_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 490.0
HKD1_k127_2473144_8 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 453.0
HKD1_k127_2473144_9 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 376.0
HKD1_k127_247763_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.708e-250 779.0
HKD1_k127_247763_1 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 1.723e-224 701.0
HKD1_k127_247763_2 sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 514.0
HKD1_k127_247763_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003392 244.0
HKD1_k127_247763_4 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000494 166.0
HKD1_k127_2490766_0 Succinyl-CoA ligase like flavodoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 586.0
HKD1_k127_2490766_1 Sodium:sulfate symporter transmembrane region K03319,K09477,K11106,K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 371.0
HKD1_k127_2493748_0 Non-ribosomal peptide synthetase modules and related - - - 2.152e-206 658.0
HKD1_k127_2493748_1 Condensation domain - - - 0.00000007713 60.0
HKD1_k127_2540458_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 3.827e-262 836.0
HKD1_k127_2540458_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 5.908e-216 692.0
HKD1_k127_2540458_10 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000007894 177.0
HKD1_k127_2540458_11 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000002393 175.0
HKD1_k127_2540458_12 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000009647 166.0
HKD1_k127_2540458_13 PFAM Sporulation domain protein - - - 0.00000000000000000000000000000000000000000001471 169.0
HKD1_k127_2540458_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000002466 150.0
HKD1_k127_2540458_15 Cell division protein ZapA K09888 - - 0.0000000000000000000000000000004045 124.0
HKD1_k127_2540458_16 - - - - 0.000000003651 59.0
HKD1_k127_2540458_17 - - - - 0.00000005386 58.0
HKD1_k127_2540458_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 7.614e-213 675.0
HKD1_k127_2540458_3 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 2.658e-199 634.0
HKD1_k127_2540458_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 567.0
HKD1_k127_2540458_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 526.0
HKD1_k127_2540458_6 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 385.0
HKD1_k127_2540458_7 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 293.0
HKD1_k127_2540458_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000225 279.0
HKD1_k127_2540458_9 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007739 242.0
HKD1_k127_2572226_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1237.0
HKD1_k127_2572226_1 FAD linked oxidase domain protein K06911 - - 0.0 1211.0
HKD1_k127_2572226_10 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 432.0
HKD1_k127_2572226_11 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 427.0
HKD1_k127_2572226_12 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 418.0
HKD1_k127_2572226_13 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 414.0
HKD1_k127_2572226_14 L-lactate dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 387.0
HKD1_k127_2572226_15 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 387.0
HKD1_k127_2572226_16 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 383.0
HKD1_k127_2572226_17 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 377.0
HKD1_k127_2572226_18 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 367.0
HKD1_k127_2572226_19 luciferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 361.0
HKD1_k127_2572226_2 Glucose / Sorbosone dehydrogenase - - - 1.245e-205 647.0
HKD1_k127_2572226_20 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 355.0
HKD1_k127_2572226_21 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 348.0
HKD1_k127_2572226_22 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 339.0
HKD1_k127_2572226_23 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 338.0
HKD1_k127_2572226_24 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 334.0
HKD1_k127_2572226_25 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 312.0
HKD1_k127_2572226_26 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 303.0
HKD1_k127_2572226_27 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001775 276.0
HKD1_k127_2572226_28 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 279.0
HKD1_k127_2572226_29 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001265 258.0
HKD1_k127_2572226_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.035e-203 639.0
HKD1_k127_2572226_30 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
HKD1_k127_2572226_31 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001256 253.0
HKD1_k127_2572226_32 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000009054 246.0
HKD1_k127_2572226_33 riboflavin synthase alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000001277 249.0
HKD1_k127_2572226_34 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000007318 240.0
HKD1_k127_2572226_35 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000001982 211.0
HKD1_k127_2572226_36 Molybdopterin-guanine dinucleotide biosynthesis protein MobA K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000003168 206.0
HKD1_k127_2572226_37 Cytochrome c K17230 - - 0.000000000000000000000000000000000000000000000000000000003299 205.0
HKD1_k127_2572226_38 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000000000000000000003937 194.0
HKD1_k127_2572226_39 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000000000000002976 190.0
HKD1_k127_2572226_4 peptidase U62, modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 553.0
HKD1_k127_2572226_40 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000007794 198.0
HKD1_k127_2572226_41 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000102 172.0
HKD1_k127_2572226_42 Cupin domain - - - 0.000000000000000000000000000000000000000000002179 170.0
HKD1_k127_2572226_43 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000002698 157.0
HKD1_k127_2572226_44 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000003812 156.0
HKD1_k127_2572226_45 Ring hydroxylating subunit beta family protein 1 - - - 0.00000000000000000000000000000004938 132.0
HKD1_k127_2572226_46 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000000001675 94.0
HKD1_k127_2572226_47 Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) K06622 GO:0000079,GO:0000082,GO:0000278,GO:0001558,GO:0001932,GO:0001933,GO:0003674,GO:0004857,GO:0004860,GO:0004861,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006469,GO:0007049,GO:0007050,GO:0007346,GO:0008150,GO:0008285,GO:0009892,GO:0009987,GO:0010563,GO:0010564,GO:0010605,GO:0016538,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0030234,GO:0030291,GO:0030308,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031657,GO:0031658,GO:0032268,GO:0032269,GO:0033673,GO:0040008,GO:0042127,GO:0042325,GO:0042326,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043549,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045736,GO:0045786,GO:0045859,GO:0045926,GO:0045936,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051726,GO:0060255,GO:0065007,GO:0065009,GO:0071900,GO:0071901,GO:0080090,GO:0098772,GO:1901987,GO:1901990,GO:1902806,GO:1903047,GO:1904029,GO:1904030,GO:2000045 - 0.0000000000001899 79.0
HKD1_k127_2572226_48 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000005724 75.0
HKD1_k127_2572226_49 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000005474 72.0
HKD1_k127_2572226_5 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 550.0
HKD1_k127_2572226_6 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 479.0
HKD1_k127_2572226_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 458.0
HKD1_k127_2572226_8 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 444.0
HKD1_k127_2572226_9 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 448.0
HKD1_k127_2579279_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.813e-266 836.0
HKD1_k127_2579279_1 4Fe-4S dicluster domain - - - 2.748e-243 771.0
HKD1_k127_2579279_10 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000001264 206.0
HKD1_k127_2579279_11 Sulfur relay protein TusC DsrF K07236 - - 0.000000000000000000000000000000000000000000000000000001291 194.0
HKD1_k127_2579279_12 DsrC like protein K11179 - - 0.000000000000000000000000000000000002084 157.0
HKD1_k127_2579279_13 DsrH like protein K07237 - - 0.000000000000000000000000000000009528 138.0
HKD1_k127_2579279_14 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000005255 120.0
HKD1_k127_2579279_15 - - - - 0.000000000000000000000000001354 118.0
HKD1_k127_2579279_16 - - - - 0.000000000000000000000004479 104.0
HKD1_k127_2579279_2 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 7.875e-221 687.0
HKD1_k127_2579279_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.02e-212 666.0
HKD1_k127_2579279_4 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 585.0
HKD1_k127_2579279_5 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 500.0
HKD1_k127_2579279_6 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 361.0
HKD1_k127_2579279_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 329.0
HKD1_k127_2579279_8 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
HKD1_k127_2579279_9 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000000000000004364 206.0
HKD1_k127_2639205_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1045.0
HKD1_k127_2639205_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.488e-290 917.0
HKD1_k127_2639205_10 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 469.0
HKD1_k127_2639205_11 DNA recombination protein, rmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 472.0
HKD1_k127_2639205_12 Transcriptional regulator K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 416.0
HKD1_k127_2639205_13 Rhodanese Homology Domain K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 398.0
HKD1_k127_2639205_14 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 397.0
HKD1_k127_2639205_15 Major Facilitator Superfamily K19577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 360.0
HKD1_k127_2639205_16 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 338.0
HKD1_k127_2639205_17 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 303.0
HKD1_k127_2639205_18 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009534 282.0
HKD1_k127_2639205_19 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000002101 216.0
HKD1_k127_2639205_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 1.439e-248 801.0
HKD1_k127_2639205_20 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000001569 228.0
HKD1_k127_2639205_21 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000001846 181.0
HKD1_k127_2639205_22 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000001267 191.0
HKD1_k127_2639205_23 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000004722 166.0
HKD1_k127_2639205_24 heme biosynthesis protein - - - 0.00000000000000000000000000000000000000001121 159.0
HKD1_k127_2639205_25 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000000000003885 154.0
HKD1_k127_2639205_26 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000734 151.0
HKD1_k127_2639205_27 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000000000002581 137.0
HKD1_k127_2639205_28 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000000000002042 134.0
HKD1_k127_2639205_29 Peptidase family U32 - - - 0.0000000002661 71.0
HKD1_k127_2639205_3 Periplasmic binding protein domain - - - 6.549e-236 749.0
HKD1_k127_2639205_30 - - - - 0.000001665 54.0
HKD1_k127_2639205_4 Cytochrome D1 heme domain - - - 7.686e-226 729.0
HKD1_k127_2639205_5 4Fe-4S single cluster domain - - - 1.285e-207 650.0
HKD1_k127_2639205_6 cytochrome d1, heme region K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 530.0
HKD1_k127_2639205_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 521.0
HKD1_k127_2639205_8 Peptidase family U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 501.0
HKD1_k127_2639205_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
HKD1_k127_2703793_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 522.0
HKD1_k127_2703793_1 PFAM Dehydrogenase, E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 265.0
HKD1_k127_2703793_2 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.0000000000000000000000001233 106.0
HKD1_k127_2710087_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.687e-230 721.0
HKD1_k127_2710087_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 3.09e-205 653.0
HKD1_k127_2710087_10 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 473.0
HKD1_k127_2710087_11 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 466.0
HKD1_k127_2710087_12 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 466.0
HKD1_k127_2710087_13 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 452.0
HKD1_k127_2710087_14 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 431.0
HKD1_k127_2710087_15 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 428.0
HKD1_k127_2710087_16 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 407.0
HKD1_k127_2710087_17 Mg2 and Co2 transporter CorC K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 393.0
HKD1_k127_2710087_18 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 389.0
HKD1_k127_2710087_19 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 365.0
HKD1_k127_2710087_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.229e-204 670.0
HKD1_k127_2710087_20 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 298.0
HKD1_k127_2710087_21 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 291.0
HKD1_k127_2710087_22 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000196 288.0
HKD1_k127_2710087_23 enzyme of heme biosynthesis K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001167 287.0
HKD1_k127_2710087_24 UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001027 269.0
HKD1_k127_2710087_25 Alginate biosynthesis regulatory protein AlgR K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003051 286.0
HKD1_k127_2710087_26 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000001881 258.0
HKD1_k127_2710087_27 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000001818 266.0
HKD1_k127_2710087_28 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000008155 258.0
HKD1_k127_2710087_29 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000003566 251.0
HKD1_k127_2710087_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.022e-199 629.0
HKD1_k127_2710087_30 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000004657 235.0
HKD1_k127_2710087_31 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
HKD1_k127_2710087_32 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000005164 183.0
HKD1_k127_2710087_33 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000009583 173.0
HKD1_k127_2710087_34 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000001701 154.0
HKD1_k127_2710087_35 Thioredoxin-like domain - - - 0.000000000000000000000000002196 119.0
HKD1_k127_2710087_36 - - - - 0.000000000000000000000006729 107.0
HKD1_k127_2710087_37 Bacterial regulatory protein, Fis family K03557 - - 0.000000000000000000003419 99.0
HKD1_k127_2710087_38 - - - - 0.000000000405 62.0
HKD1_k127_2710087_4 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 612.0
HKD1_k127_2710087_5 aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 606.0
HKD1_k127_2710087_6 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 572.0
HKD1_k127_2710087_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 532.0
HKD1_k127_2710087_8 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 505.0
HKD1_k127_2710087_9 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 516.0
HKD1_k127_2737956_0 B-1 B cell differentiation - - - 0.0000000000000000000000000000000000000000000005939 172.0
HKD1_k127_2737956_1 TIR domain - - - 0.000000000000000000000000000000001044 139.0
HKD1_k127_2737956_2 TIR domain - - - 0.000000000000000000000000001275 119.0
HKD1_k127_2737956_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000181 74.0
HKD1_k127_2786391_0 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 352.0
HKD1_k127_2786391_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000493 153.0
HKD1_k127_2786391_2 ABC transporter K06147,K18893 - - 0.000000000002093 68.0
HKD1_k127_2794806_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.087e-260 815.0
HKD1_k127_2794806_1 ribonuclease, Rne Rng family K08301 - - 3.17e-233 730.0
HKD1_k127_2794806_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000006594 158.0
HKD1_k127_2794806_11 COG3245 Cytochrome c5 - - - 0.00000000000000000000000000000000003184 140.0
HKD1_k127_2794806_12 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000007409 138.0
HKD1_k127_2794806_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 584.0
HKD1_k127_2794806_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 567.0
HKD1_k127_2794806_4 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 353.0
HKD1_k127_2794806_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 335.0
HKD1_k127_2794806_6 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000002525 227.0
HKD1_k127_2794806_7 - - - - 0.0000000000000000000000000000000000000000000000000000000001455 209.0
HKD1_k127_2794806_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000001704 179.0
HKD1_k127_2794806_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000008985 161.0
HKD1_k127_2851861_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 3.88e-258 808.0
HKD1_k127_2851861_1 Universal stress protein - - - 0.00000000000000000000000000000000000002711 148.0
HKD1_k127_2851861_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000007491 103.0
HKD1_k127_2851861_3 THUMP - - - 0.00000000000000000007646 100.0
HKD1_k127_2851861_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000009646 90.0
HKD1_k127_2882559_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 609.0
HKD1_k127_2882559_1 Dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000005948 208.0
HKD1_k127_2882559_2 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.00000000000000000000000000000000000000000000000004032 193.0
HKD1_k127_2888644_0 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 321.0
HKD1_k127_2888644_1 Ester cyclase - - - 0.0000000000000000000000000000000000000000000000000000000001631 208.0
HKD1_k127_2888644_2 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000109 203.0
HKD1_k127_2888644_3 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000005045 135.0
HKD1_k127_2888644_4 c oxidoreductase (Subunit b) - - - 0.000000000000000000001808 94.0
HKD1_k127_2895593_0 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 520.0
HKD1_k127_2895593_1 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000006948 175.0
HKD1_k127_2938872_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 300.0
HKD1_k127_2938872_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000004729 215.0
HKD1_k127_2938872_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000002094 177.0
HKD1_k127_2938872_3 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000008753 126.0
HKD1_k127_2938872_4 rhamnose metabolic process - - - 0.0000000000000000000000000001959 126.0
HKD1_k127_298150_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1038.0
HKD1_k127_298150_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.68e-264 847.0
HKD1_k127_298150_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000002933 232.0
HKD1_k127_298150_11 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000002495 196.0
HKD1_k127_298150_12 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000003834 192.0
HKD1_k127_298150_13 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000004382 184.0
HKD1_k127_298150_14 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000002035 119.0
HKD1_k127_298150_15 Sodium Bile acid symporter family - - - 0.000158 44.0
HKD1_k127_298150_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K08295 - 6.2.1.32 2.226e-231 729.0
HKD1_k127_298150_3 ribosomal rna small subunit methyltransferase - - - 2.173e-200 635.0
HKD1_k127_298150_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006327 610.0
HKD1_k127_298150_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 537.0
HKD1_k127_298150_6 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 481.0
HKD1_k127_298150_7 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 362.0
HKD1_k127_298150_8 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000002192 259.0
HKD1_k127_298150_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000005067 249.0
HKD1_k127_3015694_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.389e-286 885.0
HKD1_k127_3015694_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 623.0
HKD1_k127_3015694_2 TRAP transporter, solute receptor (TAXI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 332.0
HKD1_k127_3015694_3 alpha-ribazole phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000008128 241.0
HKD1_k127_3015694_4 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000002177 223.0
HKD1_k127_3015694_5 PFAM DsrE DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000001158 208.0
HKD1_k127_3015694_6 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000006816 120.0
HKD1_k127_3015694_8 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000001465 53.0
HKD1_k127_3019981_0 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 583.0
HKD1_k127_3019981_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 316.0
HKD1_k127_3019981_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001898 254.0
HKD1_k127_3052700_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 552.0
HKD1_k127_3052700_1 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 491.0
HKD1_k127_3052700_2 N,N-dimethylaniline monooxygenase activity K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 447.0
HKD1_k127_3052700_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 344.0
HKD1_k127_3052700_4 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001301 258.0
HKD1_k127_3052700_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000001127 222.0
HKD1_k127_3061036_0 Outer membrane efflux protein - - - 5.71e-238 760.0
HKD1_k127_3061036_1 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 604.0
HKD1_k127_3061036_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009036 265.0
HKD1_k127_3061036_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001911 206.0
HKD1_k127_3061036_4 - - - - 0.00000000000000000000000000000000000003059 153.0
HKD1_k127_3061832_0 Predicted permease K07089 - - 5.634e-220 692.0
HKD1_k127_3061832_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 426.0
HKD1_k127_3061832_2 Thioredoxin domain - - - 0.00000000000000000000000000000001192 128.0
HKD1_k127_3061834_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 552.0
HKD1_k127_3061834_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 514.0
HKD1_k127_3061834_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 409.0
HKD1_k127_3061834_3 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005628 245.0
HKD1_k127_3061834_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000001682 190.0
HKD1_k127_3061834_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000001068 158.0
HKD1_k127_3061834_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000001302 133.0
HKD1_k127_3061834_7 transcriptional regulator K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000095 93.0
HKD1_k127_3061834_8 Nitroreductase family - - - 0.0000000000008461 70.0
HKD1_k127_3061834_9 transcriptional regulator, SARP family - - - 0.000001437 59.0
HKD1_k127_3121242_0 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 7.679e-217 701.0
HKD1_k127_3130491_0 nitric oxide reductase activity K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 346.0
HKD1_k127_3130491_1 PFAM LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002658 248.0
HKD1_k127_3130491_2 - - - - 0.0000000000000000000000000000000000000000000000002417 182.0
HKD1_k127_3130491_3 YceI-like domain - - - 0.000000000000000000000000000000000000000002079 165.0
HKD1_k127_3130491_4 Cytochrome B561 K12262 - - 0.000000000000000000000000000000000000165 149.0
HKD1_k127_3130491_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000009018 146.0
HKD1_k127_3130491_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000009066 110.0
HKD1_k127_3130491_7 YceI-like domain - - - 0.00000000000000000004263 102.0
HKD1_k127_3130770_0 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 408.0
HKD1_k127_3130770_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 358.0
HKD1_k127_3130770_2 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003451 238.0
HKD1_k127_3130770_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000003329 232.0
HKD1_k127_3130770_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000002877 122.0
HKD1_k127_3131000_0 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 423.0
HKD1_k127_3131000_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000002271 228.0
HKD1_k127_3131000_2 - - - - 0.0000000000000000000000000000000000000000000000000000000005392 205.0
HKD1_k127_3131000_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000003225 126.0
HKD1_k127_3131000_4 transcriptional regulator PadR family - - - 0.00000000000000000000000007346 113.0
HKD1_k127_3131000_5 Integrase core domain - - - 0.000000000000008823 74.0
HKD1_k127_3131000_6 Curli production assembly transport component CsgG - - - 0.000000005087 64.0
HKD1_k127_3141386_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1096.0
HKD1_k127_3141386_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 4.804e-236 732.0
HKD1_k127_3141386_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 578.0
HKD1_k127_3141386_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 321.0
HKD1_k127_3141386_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000001977 171.0
HKD1_k127_3141386_5 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000004032 111.0
HKD1_k127_3143829_0 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 399.0
HKD1_k127_3143829_1 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
HKD1_k127_3168474_0 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 510.0
HKD1_k127_3168474_1 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 304.0
HKD1_k127_3168474_2 FKBP-type peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.00000000000000000000000000000000000000002012 157.0
HKD1_k127_3168474_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000001001 149.0
HKD1_k127_3168474_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001054 99.0
HKD1_k127_3183569_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 574.0
HKD1_k127_3183569_1 Cytochrome P450 - - - 0.000003356 49.0
HKD1_k127_3186830_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000001152 241.0
HKD1_k127_3186830_1 Class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000002418 177.0
HKD1_k127_3186830_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000002252 176.0
HKD1_k127_3206990_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1010.0
HKD1_k127_3206990_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 460.0
HKD1_k127_3206990_2 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 403.0
HKD1_k127_3206990_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000002986 202.0
HKD1_k127_3206990_4 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000001579 192.0
HKD1_k127_3206990_5 OHCU decarboxylase K13485 - 4.1.1.97 0.00000000000000000000000000000000000000000001825 164.0
HKD1_k127_3206990_6 - - - - 0.000006619 55.0
HKD1_k127_3269156_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.035e-283 910.0
HKD1_k127_3269156_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 1.056e-273 891.0
HKD1_k127_3269156_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 7.526e-247 767.0
HKD1_k127_3269156_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.489e-226 714.0
HKD1_k127_3269156_4 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 395.0
HKD1_k127_3269156_5 GntR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003616 246.0
HKD1_k127_3278167_0 indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 2.191e-258 819.0
HKD1_k127_3278167_1 indolepyruvate oxidoreductase subunit B K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 486.0
HKD1_k127_3278167_2 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0000000000000128 73.0
HKD1_k127_3278223_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 1.458e-263 822.0
HKD1_k127_3278223_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 584.0
HKD1_k127_3278223_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 447.0
HKD1_k127_3278223_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 337.0
HKD1_k127_3278223_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001528 272.0
HKD1_k127_3278223_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000008187 217.0
HKD1_k127_3284981_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.608e-319 985.0
HKD1_k127_3284981_1 Histidine kinase-like ATPases - - - 4.026e-274 898.0
HKD1_k127_3284981_10 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 311.0
HKD1_k127_3284981_11 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004014 244.0
HKD1_k127_3284981_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000003595 213.0
HKD1_k127_3284981_13 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000003966 220.0
HKD1_k127_3284981_14 Cupin - - - 0.000000000000000000000000000000000000000000001693 171.0
HKD1_k127_3284981_15 phosphorelay signal transduction system K11443 - - 0.0000000000000000000000000000000000002957 146.0
HKD1_k127_3284981_16 Domain of unknown function (DUF4410) - - - 0.0002141 51.0
HKD1_k127_3284981_2 FAD dependent oxidoreductase - - - 1.471e-250 780.0
HKD1_k127_3284981_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 2.881e-240 771.0
HKD1_k127_3284981_4 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 582.0
HKD1_k127_3284981_5 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 502.0
HKD1_k127_3284981_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 480.0
HKD1_k127_3284981_7 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 466.0
HKD1_k127_3284981_8 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 343.0
HKD1_k127_3284981_9 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 323.0
HKD1_k127_3300463_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 534.0
HKD1_k127_3300463_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 372.0
HKD1_k127_3300463_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 334.0
HKD1_k127_3300463_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000005231 242.0
HKD1_k127_3300463_4 Heavy-metal-associated domain K07213 - - 0.00000009602 64.0
HKD1_k127_3320574_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 398.0
HKD1_k127_3320574_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 376.0
HKD1_k127_3320574_2 NnrU protein - - - 0.0000000000000000000000000000000000000000000000002019 186.0
HKD1_k127_3320574_3 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000002839 166.0
HKD1_k127_3320574_4 Thioesterase - - - 0.000000000000000000000000000000000000000003126 158.0
HKD1_k127_3320574_5 ArsC family - - - 0.00000000000000000000000000000000000002387 148.0
HKD1_k127_3320574_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000002469 143.0
HKD1_k127_3320574_7 Protein of unknown function (DUF3422) - - - 0.000000000000000000000337 101.0
HKD1_k127_3322479_0 PFAM 4Fe-4S K00184,K21308 - - 1.638e-198 634.0
HKD1_k127_3322479_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 608.0
HKD1_k127_3322479_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009754 284.0
HKD1_k127_3322479_3 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000001757 220.0
HKD1_k127_3322479_4 cytochrome c - - - 0.000000000000000000000000000000000000000000000000000002114 205.0
HKD1_k127_3322479_5 signal sequence binding K07152 - - 0.00000000000000000000000000003765 128.0
HKD1_k127_3322479_6 - - - - 0.000000003938 64.0
HKD1_k127_3329778_0 AMP-binding enzyme C-terminal domain K00666 - - 7.365e-282 874.0
HKD1_k127_3329778_1 type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 582.0
HKD1_k127_3329778_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 370.0
HKD1_k127_3329778_11 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 321.0
HKD1_k127_3329778_12 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 315.0
HKD1_k127_3329778_13 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 313.0
HKD1_k127_3329778_14 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
HKD1_k127_3329778_15 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001363 284.0
HKD1_k127_3329778_16 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000446 231.0
HKD1_k127_3329778_17 membrane - - - 0.000000000000000000000000000000000000000000000000000000001559 216.0
HKD1_k127_3329778_18 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000003809 201.0
HKD1_k127_3329778_19 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000002432 209.0
HKD1_k127_3329778_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 546.0
HKD1_k127_3329778_20 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000001218 179.0
HKD1_k127_3329778_21 Putative zinc-finger - - - 0.00000000000000000000000000000000000000934 167.0
HKD1_k127_3329778_22 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000006604 136.0
HKD1_k127_3329778_23 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000000000000667 133.0
HKD1_k127_3329778_24 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000007452 111.0
HKD1_k127_3329778_25 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000021 99.0
HKD1_k127_3329778_26 PFAM PsiF repeat protein - - - 0.00000000000000000008875 98.0
HKD1_k127_3329778_27 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000006072 76.0
HKD1_k127_3329778_29 protein conserved in bacteria K09794 - - 0.0000000001248 69.0
HKD1_k127_3329778_3 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 523.0
HKD1_k127_3329778_30 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000001485 63.0
HKD1_k127_3329778_31 - - - - 0.0001286 52.0
HKD1_k127_3329778_32 ubiE/COQ5 methyltransferase family - - - 0.0005061 44.0
HKD1_k127_3329778_4 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 507.0
HKD1_k127_3329778_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 456.0
HKD1_k127_3329778_6 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 420.0
HKD1_k127_3329778_7 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 378.0
HKD1_k127_3329778_8 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 364.0
HKD1_k127_3329778_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 356.0
HKD1_k127_3331080_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.573e-280 868.0
HKD1_k127_3331080_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 5.166e-250 798.0
HKD1_k127_3331080_10 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 398.0
HKD1_k127_3331080_11 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 377.0
HKD1_k127_3331080_12 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 309.0
HKD1_k127_3331080_13 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000518 243.0
HKD1_k127_3331080_14 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000001658 157.0
HKD1_k127_3331080_15 Fe-S protein K06938 - - 0.00000005028 64.0
HKD1_k127_3331080_2 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.668e-244 764.0
HKD1_k127_3331080_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 5.604e-203 642.0
HKD1_k127_3331080_4 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 532.0
HKD1_k127_3331080_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 528.0
HKD1_k127_3331080_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 512.0
HKD1_k127_3331080_7 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 463.0
HKD1_k127_3331080_8 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 445.0
HKD1_k127_3331080_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 415.0
HKD1_k127_334131_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 392.0
HKD1_k127_334131_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 303.0
HKD1_k127_334131_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000001091 239.0
HKD1_k127_3349106_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 7.074e-305 956.0
HKD1_k127_3349106_1 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 6.508e-288 892.0
HKD1_k127_3349106_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 324.0
HKD1_k127_3349106_11 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 294.0
HKD1_k127_3349106_12 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003196 268.0
HKD1_k127_3349106_13 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000001743 235.0
HKD1_k127_3349106_14 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000007759 228.0
HKD1_k127_3349106_15 - - - - 0.000000000000000000000000000000000005939 154.0
HKD1_k127_3349106_16 Cytochrome c K08738 - - 0.0000000000000000000000000000001091 127.0
HKD1_k127_3349106_17 lipid carrier protein - - - 0.0000000000000000000000124 112.0
HKD1_k127_3349106_18 - - - - 0.00000000001049 68.0
HKD1_k127_3349106_19 Pfam Hemerythrin HHE - - - 0.0000000006405 71.0
HKD1_k127_3349106_2 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 3.152e-251 786.0
HKD1_k127_3349106_20 Uncharacterized conserved protein (DUF2249) - - - 0.00000003289 66.0
HKD1_k127_3349106_21 Cytochrome oxidase assembly protein K02259 - - 0.00009724 54.0
HKD1_k127_3349106_3 Cytochrome b(N-terminal)/b6/petB - - - 4.328e-245 773.0
HKD1_k127_3349106_4 PFAM Glycoside hydrolase 15-related - - - 9.372e-245 784.0
HKD1_k127_3349106_5 FMN-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 593.0
HKD1_k127_3349106_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 486.0
HKD1_k127_3349106_7 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 488.0
HKD1_k127_3349106_8 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 443.0
HKD1_k127_3349106_9 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 355.0
HKD1_k127_3364405_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 7.884e-222 705.0
HKD1_k127_3364405_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 573.0
HKD1_k127_3364405_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 409.0
HKD1_k127_3364405_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 306.0
HKD1_k127_3364405_4 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000002759 253.0
HKD1_k127_3364405_5 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000003861 175.0
HKD1_k127_3364405_6 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000003096 131.0
HKD1_k127_3364405_7 COG3245 Cytochrome c5 - - - 0.0000000000000000000000000000003611 126.0
HKD1_k127_338095_0 PFAM AMP-dependent synthetase and ligase K00666 - - 1.016e-306 982.0
HKD1_k127_338095_1 AAA domain - - - 1.874e-285 899.0
HKD1_k127_338095_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 323.0
HKD1_k127_338095_11 Methyl-transferase K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 323.0
HKD1_k127_338095_12 Beta-lactamase enzyme family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 301.0
HKD1_k127_338095_13 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000001467 252.0
HKD1_k127_338095_14 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000291 220.0
HKD1_k127_338095_15 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000003874 224.0
HKD1_k127_338095_16 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000004637 230.0
HKD1_k127_338095_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000204 157.0
HKD1_k127_338095_18 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000145 105.0
HKD1_k127_338095_19 PFAM UspA - - - 0.000000000000000000000008579 112.0
HKD1_k127_338095_2 ABC transporter transmembrane region K06147 - - 3.402e-243 764.0
HKD1_k127_338095_3 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.275e-223 708.0
HKD1_k127_338095_4 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 1.018e-212 717.0
HKD1_k127_338095_5 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 606.0
HKD1_k127_338095_6 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 592.0
HKD1_k127_338095_7 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 449.0
HKD1_k127_338095_8 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 412.0
HKD1_k127_338095_9 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 363.0
HKD1_k127_34032_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1054.0
HKD1_k127_34032_1 Required for chromosome condensation and partitioning K03529 - - 2.33e-321 1021.0
HKD1_k127_34032_10 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 476.0
HKD1_k127_34032_11 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 465.0
HKD1_k127_34032_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 444.0
HKD1_k127_34032_13 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
HKD1_k127_34032_14 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 421.0
HKD1_k127_34032_15 Psort location Cytoplasmic, score 8.96 K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 401.0
HKD1_k127_34032_16 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 391.0
HKD1_k127_34032_17 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 387.0
HKD1_k127_34032_18 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 366.0
HKD1_k127_34032_19 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 359.0
HKD1_k127_34032_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 7.387e-320 1000.0
HKD1_k127_34032_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 359.0
HKD1_k127_34032_21 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 346.0
HKD1_k127_34032_22 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 336.0
HKD1_k127_34032_23 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 331.0
HKD1_k127_34032_24 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 317.0
HKD1_k127_34032_25 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 293.0
HKD1_k127_34032_26 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002687 272.0
HKD1_k127_34032_27 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000005746 269.0
HKD1_k127_34032_28 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001206 246.0
HKD1_k127_34032_29 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000008717 235.0
HKD1_k127_34032_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.44e-304 949.0
HKD1_k127_34032_30 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006639 240.0
HKD1_k127_34032_31 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000001355 222.0
HKD1_k127_34032_32 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000001598 217.0
HKD1_k127_34032_33 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000483 207.0
HKD1_k127_34032_34 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000003908 199.0
HKD1_k127_34032_35 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000001762 203.0
HKD1_k127_34032_36 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000008871 198.0
HKD1_k127_34032_37 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000003783 176.0
HKD1_k127_34032_38 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000001639 133.0
HKD1_k127_34032_39 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000003096 128.0
HKD1_k127_34032_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.048e-263 841.0
HKD1_k127_34032_40 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000001299 128.0
HKD1_k127_34032_41 - - - - 0.000000000000003027 81.0
HKD1_k127_34032_5 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.723e-229 719.0
HKD1_k127_34032_6 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 556.0
HKD1_k127_34032_7 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 546.0
HKD1_k127_34032_8 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 519.0
HKD1_k127_34032_9 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 496.0
HKD1_k127_340508_0 Extracellular solute-binding protein - - - 1.427e-294 922.0
HKD1_k127_340508_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 1.293e-260 822.0
HKD1_k127_340508_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009931 268.0
HKD1_k127_340508_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000001163 234.0
HKD1_k127_340508_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 503.0
HKD1_k127_340508_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 511.0
HKD1_k127_340508_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 422.0
HKD1_k127_340508_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 386.0
HKD1_k127_340508_6 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 362.0
HKD1_k127_340508_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 345.0
HKD1_k127_340508_8 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 329.0
HKD1_k127_340508_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
HKD1_k127_3419396_0 Elements of external origin K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 398.0
HKD1_k127_3419396_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002103 286.0
HKD1_k127_3419396_2 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000004379 227.0
HKD1_k127_3419396_3 Homeodomain-like domain K07497 - - 0.0000000000000000000008584 102.0
HKD1_k127_3419396_4 UPF0391 membrane protein - - - 0.0000000000000001194 80.0
HKD1_k127_3419396_6 Plasmid pRiA4b ORF-3-like protein - - - 0.00000001875 61.0
HKD1_k127_342504_0 Protein of unknown function - - - 3.002e-313 1004.0
HKD1_k127_342504_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.678e-294 927.0
HKD1_k127_342504_10 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000000000000000003011 99.0
HKD1_k127_342504_11 Transcriptional regulator - - - 0.00000000000000000001059 95.0
HKD1_k127_342504_12 Zinc-finger domain - - - 0.00000000000000000006345 102.0
HKD1_k127_342504_2 modulator of DNA gyrase K03568 - - 2.051e-221 704.0
HKD1_k127_342504_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 489.0
HKD1_k127_342504_4 heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 353.0
HKD1_k127_342504_5 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 331.0
HKD1_k127_342504_6 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 286.0
HKD1_k127_342504_7 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001168 252.0
HKD1_k127_342504_8 SnoaL-like domain - - - 0.0000000000000000000000000000000004049 148.0
HKD1_k127_342504_9 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000005074 111.0
HKD1_k127_344791_0 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 403.0
HKD1_k127_344791_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 301.0
HKD1_k127_344791_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000004067 201.0
HKD1_k127_344791_3 Serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000009081 199.0
HKD1_k127_344791_4 - - - - 0.0000000000000000001315 94.0
HKD1_k127_3455173_0 PFAM ABC transporter K01990,K13926 - - 0.0 1289.0
HKD1_k127_3455173_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 547.0
HKD1_k127_3455173_2 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 425.0
HKD1_k127_3455173_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 409.0
HKD1_k127_3455173_4 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009959 237.0
HKD1_k127_3455173_5 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000008117 193.0
HKD1_k127_3455173_6 Membrane - - - 0.000000000000000000000000000000000000000000000003461 180.0
HKD1_k127_3455173_7 Cupin domain - - - 0.0000000000000000000000000000000007924 141.0
HKD1_k127_3543705_0 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 511.0
HKD1_k127_3543705_1 - - - - 0.00000000000000000002215 93.0
HKD1_k127_3594565_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
HKD1_k127_3595338_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 4.309e-227 707.0
HKD1_k127_3595338_1 peptidase m48, ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 426.0
HKD1_k127_3595338_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 395.0
HKD1_k127_3595338_3 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 359.0
HKD1_k127_3595338_4 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 353.0
HKD1_k127_3595338_5 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 308.0
HKD1_k127_3595338_6 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001909 235.0
HKD1_k127_3595338_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000005957 198.0
HKD1_k127_3595338_8 sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000001231 122.0
HKD1_k127_36700_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 469.0
HKD1_k127_36700_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 435.0
HKD1_k127_36700_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 332.0
HKD1_k127_36700_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 310.0
HKD1_k127_36700_4 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002523 298.0
HKD1_k127_36700_5 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000000001942 222.0
HKD1_k127_36700_6 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000005134 210.0
HKD1_k127_36700_7 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000001029 116.0
HKD1_k127_372020_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.434e-240 754.0
HKD1_k127_372020_1 Major Facilitator Superfamily - - - 0.00000002676 57.0
HKD1_k127_3728352_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.13e-273 859.0
HKD1_k127_3728352_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 619.0
HKD1_k127_3728352_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 562.0
HKD1_k127_3728352_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 410.0
HKD1_k127_3728352_4 Queuosine biosynthesis protein K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 405.0
HKD1_k127_3728352_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000001899 244.0
HKD1_k127_3728352_6 preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000004939 137.0
HKD1_k127_3728352_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000001837 64.0
HKD1_k127_3753499_0 Transcriptional regulatory protein, C terminal - - - 5.298e-245 766.0
HKD1_k127_3786209_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 626.0
HKD1_k127_3786209_1 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 516.0
HKD1_k127_3786209_10 GMP synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005071 250.0
HKD1_k127_3786209_11 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000002251 171.0
HKD1_k127_3786209_12 - - - - 0.00000000000000000000000000004659 119.0
HKD1_k127_3786209_13 - - - - 0.0000000000000000000000000001352 119.0
HKD1_k127_3786209_14 - - - - 0.00000000000000000000000000999 115.0
HKD1_k127_3786209_15 membrane - - - 0.00000000000000000008763 90.0
HKD1_k127_3786209_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 480.0
HKD1_k127_3786209_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 418.0
HKD1_k127_3786209_4 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 419.0
HKD1_k127_3786209_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 398.0
HKD1_k127_3786209_6 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 396.0
HKD1_k127_3786209_7 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 364.0
HKD1_k127_3786209_8 phytoene K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 321.0
HKD1_k127_3786209_9 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001499 306.0
HKD1_k127_3811643_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 338.0
HKD1_k127_3811643_1 - - - - 0.00000000000000000000001763 105.0
HKD1_k127_3838354_0 Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 326.0
HKD1_k127_3838354_1 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005549 250.0
HKD1_k127_3838354_2 stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000933 164.0
HKD1_k127_3838354_3 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000001982 145.0
HKD1_k127_3838354_4 - - - - 0.000000000000000000000000003769 116.0
HKD1_k127_387598_0 COG0474 Cation transport ATPase - - - 6.359e-298 960.0
HKD1_k127_387598_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.166e-292 903.0
HKD1_k127_387598_2 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 537.0
HKD1_k127_387598_3 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 407.0
HKD1_k127_3898337_0 Allophanate hydrolase K01457 - 3.5.1.54 4.919e-215 683.0
HKD1_k127_3898337_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.863e-197 622.0
HKD1_k127_3898337_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000003924 168.0
HKD1_k127_3898337_11 - - - - 0.0000000000000000000000000003033 123.0
HKD1_k127_3898337_2 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 573.0
HKD1_k127_3898337_3 CoA-ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 481.0
HKD1_k127_3898337_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 464.0
HKD1_k127_3898337_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 471.0
HKD1_k127_3898337_6 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 370.0
HKD1_k127_3898337_7 PERMEase K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 348.0
HKD1_k127_3898337_8 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 339.0
HKD1_k127_3898337_9 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000001623 206.0
HKD1_k127_3906068_0 Alpha beta hydrolase K03821 - - 3.736e-233 735.0
HKD1_k127_3906068_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.853e-206 654.0
HKD1_k127_3906068_10 AntiSigma factor - - - 0.0000000000000000000000000000000000001918 156.0
HKD1_k127_3906068_11 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000003775 151.0
HKD1_k127_3906068_12 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000005604 142.0
HKD1_k127_3906068_13 DsrE/DsrF-like family - - - 0.000000000000000000000000000000002754 133.0
HKD1_k127_3906068_14 DsrE/DsrF-like family - - - 0.0000000000000000000000000000001797 128.0
HKD1_k127_3906068_15 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000000001132 120.0
HKD1_k127_3906068_16 epsilon subunit K02114 - - 0.00000000000000000000001069 117.0
HKD1_k127_3906068_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000692 115.0
HKD1_k127_3906068_18 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000766 100.0
HKD1_k127_3906068_19 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000002713 57.0
HKD1_k127_3906068_2 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 615.0
HKD1_k127_3906068_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 380.0
HKD1_k127_3906068_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HKD1_k127_3906068_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 291.0
HKD1_k127_3906068_6 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000001345 194.0
HKD1_k127_3906068_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000001418 186.0
HKD1_k127_3906068_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000003002 168.0
HKD1_k127_3906068_9 ATP synthase K02115 - - 0.000000000000000000000000000000000000007924 167.0
HKD1_k127_3991983_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 543.0
HKD1_k127_3991983_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 527.0
HKD1_k127_3991983_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 405.0
HKD1_k127_3991983_3 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
HKD1_k127_3991983_4 PFAM MaoC like domain - - - 0.0000000000000000000000000000000008031 144.0
HKD1_k127_4023662_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.683e-286 907.0
HKD1_k127_4023662_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.569e-210 662.0
HKD1_k127_4023662_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 346.0
HKD1_k127_4023662_11 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 322.0
HKD1_k127_4023662_12 response regulator K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
HKD1_k127_4023662_13 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 294.0
HKD1_k127_4023662_14 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001085 266.0
HKD1_k127_4023662_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002771 268.0
HKD1_k127_4023662_16 Hydrolase, P-loop family K06925 - - 0.000000000000000000000000000000000000000000005088 168.0
HKD1_k127_4023662_17 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000003958 167.0
HKD1_k127_4023662_18 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000001383 158.0
HKD1_k127_4023662_19 - - - - 0.000000000000000000000002501 111.0
HKD1_k127_4023662_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 602.0
HKD1_k127_4023662_20 Protein of Unknown function (DUF2784) - - - 0.00000000000000000162 98.0
HKD1_k127_4023662_21 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001359 85.0
HKD1_k127_4023662_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 548.0
HKD1_k127_4023662_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 490.0
HKD1_k127_4023662_5 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 486.0
HKD1_k127_4023662_6 rieske 2fe-2s K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 473.0
HKD1_k127_4023662_7 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 418.0
HKD1_k127_4023662_8 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 390.0
HKD1_k127_4023662_9 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 359.0
HKD1_k127_4038024_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 412.0
HKD1_k127_4038024_1 Domain of unknown function (DUF4345) - - - 0.0000000000000000000008859 99.0
HKD1_k127_4064265_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1071.0
HKD1_k127_4064265_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 7.125e-240 758.0
HKD1_k127_4064265_10 cold-shock protein K03704 - - 0.0000000000000000000000000000005328 123.0
HKD1_k127_4064265_11 - - - - 0.0000005898 53.0
HKD1_k127_4064265_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.042e-203 639.0
HKD1_k127_4064265_3 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 591.0
HKD1_k127_4064265_4 LPPG Fo 2-phospho-L-lactate transferase K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005123 277.0
HKD1_k127_4064265_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000001999 253.0
HKD1_k127_4064265_6 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
HKD1_k127_4064265_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000122 234.0
HKD1_k127_4064265_8 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000000007302 206.0
HKD1_k127_4064265_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000004053 176.0
HKD1_k127_4091753_0 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 7.979e-195 618.0
HKD1_k127_4091753_1 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000004921 81.0
HKD1_k127_4091753_2 PFAM Cytochrome C - - - 0.000000000003843 70.0
HKD1_k127_4102542_0 UPF0210 protein K09157 - - 1.033e-213 671.0
HKD1_k127_4102542_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 377.0
HKD1_k127_4102542_2 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004327 278.0
HKD1_k127_4106360_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1391.0
HKD1_k127_4106360_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 1.123e-309 971.0
HKD1_k127_4106360_10 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 426.0
HKD1_k127_4106360_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 419.0
HKD1_k127_4106360_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 410.0
HKD1_k127_4106360_13 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
HKD1_k127_4106360_14 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 361.0
HKD1_k127_4106360_15 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 339.0
HKD1_k127_4106360_16 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 331.0
HKD1_k127_4106360_17 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 327.0
HKD1_k127_4106360_18 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 323.0
HKD1_k127_4106360_19 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 313.0
HKD1_k127_4106360_2 Dehydratase family K13875 - 4.2.1.25 9.54e-309 955.0
HKD1_k127_4106360_20 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 314.0
HKD1_k127_4106360_21 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 301.0
HKD1_k127_4106360_22 TIGRFAM malate synthase A K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000034 258.0
HKD1_k127_4106360_23 RNA methyltransferase K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000001357 220.0
HKD1_k127_4106360_24 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000007681 166.0
HKD1_k127_4106360_25 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000469 113.0
HKD1_k127_4106360_26 Domain of unknown function (DUF4189) - - - 0.0000000004124 72.0
HKD1_k127_4106360_3 Dehydrogenase K00382 - 1.8.1.4 6.675e-271 844.0
HKD1_k127_4106360_4 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.292e-215 672.0
HKD1_k127_4106360_5 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 1.957e-210 692.0
HKD1_k127_4106360_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 5.562e-206 648.0
HKD1_k127_4106360_7 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 548.0
HKD1_k127_4106360_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 518.0
HKD1_k127_4106360_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 480.0
HKD1_k127_412138_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 2.469e-299 936.0
HKD1_k127_412138_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.4e-289 895.0
HKD1_k127_412138_10 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 436.0
HKD1_k127_412138_11 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 370.0
HKD1_k127_412138_12 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 326.0
HKD1_k127_412138_13 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
HKD1_k127_412138_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 297.0
HKD1_k127_412138_15 PFAM class II aldolase adducin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001129 285.0
HKD1_k127_412138_16 Nicotinamidase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001407 237.0
HKD1_k127_412138_17 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000002442 200.0
HKD1_k127_412138_18 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000009273 180.0
HKD1_k127_412138_19 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000004158 150.0
HKD1_k127_412138_2 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 9.091e-285 886.0
HKD1_k127_412138_20 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000001373 135.0
HKD1_k127_412138_21 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000001873 110.0
HKD1_k127_412138_23 hyperosmotic response K04065 - - 0.0002962 49.0
HKD1_k127_412138_3 DNA polymerase X family K02347 - - 6e-244 768.0
HKD1_k127_412138_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.523e-243 762.0
HKD1_k127_412138_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.174e-213 674.0
HKD1_k127_412138_6 homoserine dehydrogenase - - - 1.058e-212 669.0
HKD1_k127_412138_7 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 557.0
HKD1_k127_412138_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 554.0
HKD1_k127_412138_9 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 522.0
HKD1_k127_4137632_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1395.0
HKD1_k127_4137632_1 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1187.0
HKD1_k127_4137632_10 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 490.0
HKD1_k127_4137632_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 475.0
HKD1_k127_4137632_12 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 464.0
HKD1_k127_4137632_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 464.0
HKD1_k127_4137632_14 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 429.0
HKD1_k127_4137632_15 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 426.0
HKD1_k127_4137632_16 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 426.0
HKD1_k127_4137632_17 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 389.0
HKD1_k127_4137632_18 Including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 386.0
HKD1_k127_4137632_19 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 351.0
HKD1_k127_4137632_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.796e-286 904.0
HKD1_k127_4137632_20 amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 352.0
HKD1_k127_4137632_21 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 346.0
HKD1_k127_4137632_22 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 346.0
HKD1_k127_4137632_23 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 338.0
HKD1_k127_4137632_24 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 334.0
HKD1_k127_4137632_25 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 343.0
HKD1_k127_4137632_26 to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 336.0
HKD1_k127_4137632_27 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 303.0
HKD1_k127_4137632_28 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001827 284.0
HKD1_k127_4137632_29 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002671 280.0
HKD1_k127_4137632_3 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 2.453e-228 713.0
HKD1_k127_4137632_30 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001025 294.0
HKD1_k127_4137632_31 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 264.0
HKD1_k127_4137632_32 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000002331 228.0
HKD1_k127_4137632_33 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000001831 187.0
HKD1_k127_4137632_34 Phasin protein - - - 0.000000000000000000000000000000000000000000000000004169 188.0
HKD1_k127_4137632_35 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000003571 176.0
HKD1_k127_4137632_36 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000003643 179.0
HKD1_k127_4137632_37 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000002616 183.0
HKD1_k127_4137632_38 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.000000000000000000000000000000000000000002609 158.0
HKD1_k127_4137632_39 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000004165 161.0
HKD1_k127_4137632_4 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.949e-221 696.0
HKD1_k127_4137632_40 Cold shock K03704 - - 0.0000000000000000000000000000000000164 138.0
HKD1_k127_4137632_41 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000005797 121.0
HKD1_k127_4137632_42 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000004096 109.0
HKD1_k127_4137632_43 - - - - 0.00000000000000000000009878 102.0
HKD1_k127_4137632_44 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000002311 93.0
HKD1_k127_4137632_45 Protein of unknown function (DUF3108) - - - 0.00000000000000000002874 101.0
HKD1_k127_4137632_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.7e-211 664.0
HKD1_k127_4137632_6 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 2.204e-206 657.0
HKD1_k127_4137632_7 glycolate oxidase iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 574.0
HKD1_k127_4137632_8 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 571.0
HKD1_k127_4137632_9 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 522.0
HKD1_k127_4140085_0 6-phosphogluconate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 434.0
HKD1_k127_4140085_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 372.0
HKD1_k127_4140085_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000003208 243.0
HKD1_k127_4146581_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 316.0
HKD1_k127_4146581_1 Hep Hag repeat protein K21449 - - 0.0000000000000000000000000000000000000000000000000001754 208.0
HKD1_k127_4159689_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 464.0
HKD1_k127_4159689_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 319.0
HKD1_k127_4160283_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1641.0
HKD1_k127_4160283_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1468.0
HKD1_k127_4160283_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000008357 153.0
HKD1_k127_4160283_11 NifU-like domain K19168 - - 0.00000000000000000000272 108.0
HKD1_k127_4160283_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 9.164e-244 758.0
HKD1_k127_4160283_3 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 489.0
HKD1_k127_4160283_4 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 361.0
HKD1_k127_4160283_5 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 321.0
HKD1_k127_4160283_6 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 317.0
HKD1_k127_4160283_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000006496 258.0
HKD1_k127_4160283_8 Phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000002612 270.0
HKD1_k127_4160283_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000006132 205.0
HKD1_k127_4164171_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1256.0
HKD1_k127_4164171_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.407e-288 895.0
HKD1_k127_4164171_2 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 284.0
HKD1_k127_4164171_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 278.0
HKD1_k127_4164171_4 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000002623 232.0
HKD1_k127_4164171_5 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000000000003035 148.0
HKD1_k127_4164171_6 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000003459 151.0
HKD1_k127_4173701_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.486e-302 941.0
HKD1_k127_4173701_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 4.037e-241 756.0
HKD1_k127_4173701_10 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 487.0
HKD1_k127_4173701_11 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 476.0
HKD1_k127_4173701_12 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 439.0
HKD1_k127_4173701_13 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 435.0
HKD1_k127_4173701_14 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 430.0
HKD1_k127_4173701_15 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 441.0
HKD1_k127_4173701_16 AsmA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 447.0
HKD1_k127_4173701_17 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 417.0
HKD1_k127_4173701_18 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 410.0
HKD1_k127_4173701_19 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 409.0
HKD1_k127_4173701_2 Domain of unknown function (DUF4070) - - - 3.823e-226 710.0
HKD1_k127_4173701_20 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 402.0
HKD1_k127_4173701_21 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 391.0
HKD1_k127_4173701_22 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 372.0
HKD1_k127_4173701_23 Trypsin K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 366.0
HKD1_k127_4173701_24 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 364.0
HKD1_k127_4173701_25 ABC transport system ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 362.0
HKD1_k127_4173701_26 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 349.0
HKD1_k127_4173701_27 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 342.0
HKD1_k127_4173701_28 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 323.0
HKD1_k127_4173701_29 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 314.0
HKD1_k127_4173701_3 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 2.818e-218 696.0
HKD1_k127_4173701_30 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 325.0
HKD1_k127_4173701_31 Stress-induced protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006026 284.0
HKD1_k127_4173701_32 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001579 289.0
HKD1_k127_4173701_33 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 275.0
HKD1_k127_4173701_34 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005539 258.0
HKD1_k127_4173701_35 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002313 263.0
HKD1_k127_4173701_36 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000005756 260.0
HKD1_k127_4173701_37 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000128 254.0
HKD1_k127_4173701_38 ATPase activity, coupled to transmembrane movement of substances - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001308 248.0
HKD1_k127_4173701_39 Putative metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 245.0
HKD1_k127_4173701_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 550.0
HKD1_k127_4173701_40 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000003982 237.0
HKD1_k127_4173701_41 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
HKD1_k127_4173701_42 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.000000000000000000000000000000000000000000000000000000000000002451 223.0
HKD1_k127_4173701_43 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000000000000000113 216.0
HKD1_k127_4173701_44 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000005418 214.0
HKD1_k127_4173701_45 peptidase S16 K07157 - - 0.0000000000000000000000000000000000000000000000000000000000672 213.0
HKD1_k127_4173701_46 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000003508 203.0
HKD1_k127_4173701_47 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000006729 199.0
HKD1_k127_4173701_48 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000009755 174.0
HKD1_k127_4173701_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 541.0
HKD1_k127_4173701_50 ATP-binding protein K01990 - - 0.00000000000000000000000000000000000009289 152.0
HKD1_k127_4173701_51 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000006402 151.0
HKD1_k127_4173701_52 sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000005059 153.0
HKD1_k127_4173701_53 general secretion pathway protein - - - 0.0000000000000000000000000000000008937 148.0
HKD1_k127_4173701_54 protein conserved in bacteria K11719 - - 0.0000000000000000000000000000002188 136.0
HKD1_k127_4173701_55 OstA-like protein K09774 - - 0.000000000000000000000000000008574 128.0
HKD1_k127_4173701_56 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000002484 109.0
HKD1_k127_4173701_57 - - - - 0.0000000000000000009851 94.0
HKD1_k127_4173701_58 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00000000000000000531 85.0
HKD1_k127_4173701_59 - - - - 0.000000000001858 78.0
HKD1_k127_4173701_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 510.0
HKD1_k127_4173701_60 transporter antisigma-factor antagonist STAS K07122 - - 0.0000000006626 70.0
HKD1_k127_4173701_7 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 507.0
HKD1_k127_4173701_8 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 487.0
HKD1_k127_4173701_9 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 483.0
HKD1_k127_4190968_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2350.0
HKD1_k127_4190968_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.504e-265 829.0
HKD1_k127_4190968_10 fimbrial biogenesis protein PilN K02663 - - 0.00000000000000000000000000000000000000000000000000000000002783 212.0
HKD1_k127_4190968_11 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000005488 143.0
HKD1_k127_4190968_12 Cytochrome c - - - 0.00000000000000000000009296 100.0
HKD1_k127_4190968_13 translation initiation inhibitor, yjgF family - - - 0.00000000000000004902 80.0
HKD1_k127_4190968_2 Type 4 fimbrial biogenesis protein K02666 - - 8.977e-249 786.0
HKD1_k127_4190968_3 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 6.705e-244 760.0
HKD1_k127_4190968_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 549.0
HKD1_k127_4190968_5 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 481.0
HKD1_k127_4190968_6 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 476.0
HKD1_k127_4190968_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 442.0
HKD1_k127_4190968_8 Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000148 270.0
HKD1_k127_4190968_9 Shikimate kinase K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000001874 217.0
HKD1_k127_4207818_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.192e-275 862.0
HKD1_k127_4207818_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.387e-271 851.0
HKD1_k127_4207818_10 transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 445.0
HKD1_k127_4207818_11 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 392.0
HKD1_k127_4207818_12 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 370.0
HKD1_k127_4207818_13 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
HKD1_k127_4207818_14 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 366.0
HKD1_k127_4207818_15 PFAM aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 386.0
HKD1_k127_4207818_16 Alcohol dehydrogenase GroES-like domain K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 353.0
HKD1_k127_4207818_17 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 332.0
HKD1_k127_4207818_18 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 310.0
HKD1_k127_4207818_19 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 304.0
HKD1_k127_4207818_2 AMP-binding enzyme C-terminal domain - - - 5.268e-226 715.0
HKD1_k127_4207818_20 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 288.0
HKD1_k127_4207818_21 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009823 269.0
HKD1_k127_4207818_22 COG0410 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001107 265.0
HKD1_k127_4207818_23 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000005602 223.0
HKD1_k127_4207818_24 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001261 201.0
HKD1_k127_4207818_25 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000787 200.0
HKD1_k127_4207818_26 Copper resistance protein D - - - 0.000000000000000000000000000000000000000000000009338 175.0
HKD1_k127_4207818_27 NUDIX domain - - - 0.0000000000000000000000000000000000000000000009403 170.0
HKD1_k127_4207818_28 Glutaredoxin - - - 0.000000000000000000000000000000000000000000004497 166.0
HKD1_k127_4207818_29 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000001373 148.0
HKD1_k127_4207818_3 abc transporter K15738 - - 4.679e-205 653.0
HKD1_k127_4207818_30 - - - - 0.000000000000000000000000313 113.0
HKD1_k127_4207818_31 Transcriptional regulator - - - 0.0000000000000006217 85.0
HKD1_k127_4207818_32 Sporulation related domain K03749 - - 0.0000007066 63.0
HKD1_k127_4207818_33 AMP-binding enzyme C-terminal domain K04116 - - 0.0001006 53.0
HKD1_k127_4207818_4 Phosphoesterase family - - - 1.913e-200 636.0
HKD1_k127_4207818_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 589.0
HKD1_k127_4207818_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 567.0
HKD1_k127_4207818_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 537.0
HKD1_k127_4207818_8 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 517.0
HKD1_k127_4207818_9 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 458.0
HKD1_k127_4216661_0 4Fe-4S dicluster domain - - - 0.0 1219.0
HKD1_k127_4216661_1 Belongs to the IlvD Edd family - - - 3.981e-271 843.0
HKD1_k127_4216661_10 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 430.0
HKD1_k127_4216661_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 380.0
HKD1_k127_4216661_12 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 380.0
HKD1_k127_4216661_13 Histidine kinase K07641 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 377.0
HKD1_k127_4216661_14 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 362.0
HKD1_k127_4216661_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 308.0
HKD1_k127_4216661_16 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 323.0
HKD1_k127_4216661_17 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 292.0
HKD1_k127_4216661_18 membrane transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006427 288.0
HKD1_k127_4216661_19 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000001128 246.0
HKD1_k127_4216661_2 Protein of unknown function, DUF255 K06888 - - 1.703e-256 808.0
HKD1_k127_4216661_20 PFAM Bacterial protein of - - - 0.000000000000000000000000000000000000000000000000000000000000004407 222.0
HKD1_k127_4216661_21 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000002099 201.0
HKD1_k127_4216661_22 Cytochrome c K08738 - - 0.00000000000000000000000000000000002814 137.0
HKD1_k127_4216661_23 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000004222 96.0
HKD1_k127_4216661_24 Histidine kinase K07641 - 2.7.13.3 0.000000007611 68.0
HKD1_k127_4216661_3 PFAM AMP-dependent synthetase and ligase - - - 1.226e-229 720.0
HKD1_k127_4216661_4 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 3.652e-202 640.0
HKD1_k127_4216661_5 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 591.0
HKD1_k127_4216661_6 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 557.0
HKD1_k127_4216661_7 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 505.0
HKD1_k127_4216661_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 471.0
HKD1_k127_4216661_9 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 470.0
HKD1_k127_4297949_0 PFAM acyltransferase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001211 260.0
HKD1_k127_4297949_1 CBS domain - - - 0.0000000000000000000000000000000000000000000000000002924 187.0
HKD1_k127_4342952_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000009284 263.0
HKD1_k127_4342952_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001467 259.0
HKD1_k127_4342952_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000001593 109.0
HKD1_k127_4342952_3 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000007301 96.0
HKD1_k127_4342952_4 KR domain - - - 0.00000000000000000003047 91.0
HKD1_k127_4350288_0 reductase, alpha subunit K00394 - 1.8.99.2 5.11e-293 900.0
HKD1_k127_4350288_1 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 559.0
HKD1_k127_4350288_10 - - - - 0.00000000000005958 74.0
HKD1_k127_4350288_2 PFAM AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 387.0
HKD1_k127_4350288_3 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 343.0
HKD1_k127_4350288_4 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000561 310.0
HKD1_k127_4350288_5 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000003056 244.0
HKD1_k127_4350288_6 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000001148 220.0
HKD1_k127_4350288_7 YhhN family - - - 0.00000000000000000000000000000000000000001708 160.0
HKD1_k127_4350288_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000001851 159.0
HKD1_k127_4350288_9 Response regulator, receiver - - - 0.000000000000000000000000000001226 133.0
HKD1_k127_4360161_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.365e-312 964.0
HKD1_k127_4360161_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.483e-269 854.0
HKD1_k127_4360161_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 440.0
HKD1_k127_4360161_11 signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 428.0
HKD1_k127_4360161_12 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 424.0
HKD1_k127_4360161_13 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 413.0
HKD1_k127_4360161_14 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 392.0
HKD1_k127_4360161_15 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 384.0
HKD1_k127_4360161_16 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 385.0
HKD1_k127_4360161_17 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 367.0
HKD1_k127_4360161_18 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 356.0
HKD1_k127_4360161_19 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 347.0
HKD1_k127_4360161_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.581e-234 738.0
HKD1_k127_4360161_20 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 337.0
HKD1_k127_4360161_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 313.0
HKD1_k127_4360161_22 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 303.0
HKD1_k127_4360161_23 negative regulator of sigma E activity K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002338 265.0
HKD1_k127_4360161_24 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007062 252.0
HKD1_k127_4360161_25 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000001285 250.0
HKD1_k127_4360161_26 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000009401 248.0
HKD1_k127_4360161_27 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005076 250.0
HKD1_k127_4360161_28 S-adenosylmethionine-dependent methyltransferase, YraL family K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000001124 243.0
HKD1_k127_4360161_29 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000002053 233.0
HKD1_k127_4360161_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.057e-210 660.0
HKD1_k127_4360161_30 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
HKD1_k127_4360161_31 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000008144 169.0
HKD1_k127_4360161_32 Belongs to the ompA family - - - 0.000000000000000000000000000000000000007382 155.0
HKD1_k127_4360161_33 FecR protein - - - 0.0000000000000000000000000000000000003371 145.0
HKD1_k127_4360161_34 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000002699 136.0
HKD1_k127_4360161_35 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000007892 135.0
HKD1_k127_4360161_36 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000008465 123.0
HKD1_k127_4360161_37 rieske 2fe-2s - - - 0.00000000000000000000000000001172 128.0
HKD1_k127_4360161_38 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000009142 110.0
HKD1_k127_4360161_39 Psort location Cytoplasmic, score 8.96 K07040 - - 0.000000000000000000000000162 112.0
HKD1_k127_4360161_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.309e-210 667.0
HKD1_k127_4360161_40 Domain of unknown function (DUF4845) - - - 0.0000000000000000000000003836 108.0
HKD1_k127_4360161_41 STAS domain K06378 - - 0.00000000000000000000003122 103.0
HKD1_k127_4360161_42 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000000000000006438 106.0
HKD1_k127_4360161_43 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.0000000000000000000005069 97.0
HKD1_k127_4360161_44 Histidine kinase-like ATPase domain - - - 0.000000000000001962 84.0
HKD1_k127_4360161_46 - - - - 0.000747 50.0
HKD1_k127_4360161_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.331e-199 632.0
HKD1_k127_4360161_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 563.0
HKD1_k127_4360161_7 COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 496.0
HKD1_k127_4360161_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 478.0
HKD1_k127_4360161_9 CHASE2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 485.0
HKD1_k127_4361311_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2170.0
HKD1_k127_4361311_1 Nitrate reductase, beta subunit K00371 - 1.7.5.1 2.186e-297 916.0
HKD1_k127_4361311_10 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000002383 133.0
HKD1_k127_4361311_11 Protein of unknown function (DUF2945) - - - 0.00000000000000000000000002036 113.0
HKD1_k127_4361311_12 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000306 96.0
HKD1_k127_4361311_13 - - - - 0.0000000000000000004907 90.0
HKD1_k127_4361311_14 - - - - 0.000000003487 59.0
HKD1_k127_4361311_2 PFAM major facilitator superfamily MFS_1 K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 566.0
HKD1_k127_4361311_3 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 381.0
HKD1_k127_4361311_4 Respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 304.0
HKD1_k127_4361311_5 Peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001482 257.0
HKD1_k127_4361311_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
HKD1_k127_4361311_7 Nitrate reductase K00373 - - 0.000000000000000000000000000000000000000000000000007156 191.0
HKD1_k127_4361311_8 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000002478 183.0
HKD1_k127_4361311_9 Regulatory protein MarR - - - 0.000000000000000000000000000000000004056 139.0
HKD1_k127_4412966_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.847e-250 785.0
HKD1_k127_4412966_1 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 604.0
HKD1_k127_4412966_10 Psort location CytoplasmicMembrane, score 10.00 K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 361.0
HKD1_k127_4412966_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 375.0
HKD1_k127_4412966_12 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 357.0
HKD1_k127_4412966_13 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 347.0
HKD1_k127_4412966_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 337.0
HKD1_k127_4412966_15 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 302.0
HKD1_k127_4412966_16 PFAM Dimethylmenaquinone methyltransferase K02553,K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 298.0
HKD1_k127_4412966_17 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002324 281.0
HKD1_k127_4412966_18 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003558 286.0
HKD1_k127_4412966_19 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003814 273.0
HKD1_k127_4412966_2 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 429.0
HKD1_k127_4412966_20 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004818 275.0
HKD1_k127_4412966_21 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005077 254.0
HKD1_k127_4412966_22 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003159 257.0
HKD1_k127_4412966_23 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009235 250.0
HKD1_k127_4412966_24 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000001203 211.0
HKD1_k127_4412966_25 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000003243 217.0
HKD1_k127_4412966_26 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000003671 208.0
HKD1_k127_4412966_27 Metal-binding integral membrane protein - - - 0.000000000000000000000000000000000000000007094 177.0
HKD1_k127_4412966_28 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000012 155.0
HKD1_k127_4412966_29 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.00000000000000000000000000000005565 140.0
HKD1_k127_4412966_3 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 430.0
HKD1_k127_4412966_30 - - - - 0.0000000000000000000000000000002461 128.0
HKD1_k127_4412966_31 Transglycosylase associated protein - - - 0.000000000000000000000000005333 116.0
HKD1_k127_4412966_32 Thioesterase superfamily - - - 0.00000000000000000000000001676 114.0
HKD1_k127_4412966_33 Rubrerythrin - - - 0.000000000000000000002622 106.0
HKD1_k127_4412966_34 ISXO2-like transposase domain - - - 0.000000000000000000003545 99.0
HKD1_k127_4412966_35 transposase activity K07483,K07497 - - 0.000000000000000000008414 95.0
HKD1_k127_4412966_36 2'-5' RNA ligase superfamily - - - 0.00000000000000000000905 99.0
HKD1_k127_4412966_37 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008653,GO:0009279,GO:0009311,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0042802,GO:0042803,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044462,GO:0044464,GO:0046493,GO:0046983,GO:0050528,GO:0052689,GO:0071704,GO:0071944,GO:1901135,GO:1901269,GO:1903509 - 0.0000000000000000003182 99.0
HKD1_k127_4412966_38 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000002249 88.0
HKD1_k127_4412966_39 Rubrerythrin - - - 0.00000122 57.0
HKD1_k127_4412966_4 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 432.0
HKD1_k127_4412966_40 - - - - 0.000005543 51.0
HKD1_k127_4412966_41 Tripartite tricarboxylate transporter TctB family - - - 0.00003848 52.0
HKD1_k127_4412966_5 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 421.0
HKD1_k127_4412966_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 408.0
HKD1_k127_4412966_7 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 404.0
HKD1_k127_4412966_8 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide K01574 - 4.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 404.0
HKD1_k127_4412966_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 372.0
HKD1_k127_4413407_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1072.0
HKD1_k127_4413407_1 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 547.0
HKD1_k127_4413407_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 491.0
HKD1_k127_4413407_3 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000008811 244.0
HKD1_k127_4413407_4 Ribonuclease B OB domain K03704 - - 0.00000000000000000000000000004068 119.0
HKD1_k127_4413407_5 long-chain fatty acid transport protein - - - 0.0000000000000000000000005899 110.0
HKD1_k127_4413407_6 PFAM Integrase catalytic - - - 0.00000000000000000001475 94.0
HKD1_k127_441623_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 378.0
HKD1_k127_441623_1 Ketopantoate reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 318.0
HKD1_k127_441623_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003347 245.0
HKD1_k127_441623_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033744,GO:0036456,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114,GO:0071704,GO:1901564 1.8.4.11 0.00000000000000000001024 94.0
HKD1_k127_441623_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000001308 76.0
HKD1_k127_44528_0 FtsX-like permease family K02004 - - 4.698e-319 1010.0
HKD1_k127_44528_1 Peptidase family M3 K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 376.0
HKD1_k127_44528_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 330.0
HKD1_k127_44528_3 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 306.0
HKD1_k127_44528_4 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000000000000000000000205 174.0
HKD1_k127_447282_0 Molecular chaperone. Has ATPase activity K04079 - - 2.518e-282 891.0
HKD1_k127_447282_1 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 410.0
HKD1_k127_447282_2 Thioredoxin-like K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 388.0
HKD1_k127_447282_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 319.0
HKD1_k127_447282_4 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 313.0
HKD1_k127_447282_5 - - - - 0.0000000000000000000000000000000008971 141.0
HKD1_k127_447282_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000003888 119.0
HKD1_k127_448654_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1778.0
HKD1_k127_448654_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 524.0
HKD1_k127_448654_10 Thioesterase superfamily - - - 0.00000000000000000000000008366 111.0
HKD1_k127_448654_11 oxygen carrier activity K03406,K07216 - - 0.0000000000000002604 91.0
HKD1_k127_448654_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 486.0
HKD1_k127_448654_3 KR domain K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 360.0
HKD1_k127_448654_4 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 345.0
HKD1_k127_448654_5 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 344.0
HKD1_k127_448654_6 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000715 281.0
HKD1_k127_448654_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 280.0
HKD1_k127_448654_8 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004173 280.0
HKD1_k127_448654_9 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
HKD1_k127_4512231_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2465.0
HKD1_k127_4512231_1 serine protease K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 498.0
HKD1_k127_4512231_2 Alpha beta hydrolase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 366.0
HKD1_k127_4512231_3 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
HKD1_k127_4512231_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000001703 218.0
HKD1_k127_4519174_0 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000009181 174.0
HKD1_k127_4519174_1 Flavin reductase like domain K13786 - 1.16.8.1 0.000000000000000000000000000000000001057 145.0
HKD1_k127_4519174_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000009225 78.0
HKD1_k127_4527973_0 Polysaccharide chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 439.0
HKD1_k127_4527973_1 COG0489 ATPases involved in chromosome partitioning K08252 - 2.7.10.1 0.000000000000000000000000000000000005221 148.0
HKD1_k127_4540959_0 Sugar (and other) transporter - - - 2.265e-198 627.0
HKD1_k127_4540959_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003315 242.0
HKD1_k127_4540959_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000002329 60.0
HKD1_k127_46552_0 DNA polymerase K02337 - 2.7.7.7 0.0 1411.0
HKD1_k127_46552_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.217e-297 927.0
HKD1_k127_46552_10 two component, sigma54 specific, transcriptional regulator, Fis family K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 556.0
HKD1_k127_46552_11 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 547.0
HKD1_k127_46552_12 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 558.0
HKD1_k127_46552_13 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 538.0
HKD1_k127_46552_14 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 494.0
HKD1_k127_46552_15 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 493.0
HKD1_k127_46552_16 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 466.0
HKD1_k127_46552_17 HD domain K13815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 412.0
HKD1_k127_46552_18 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 371.0
HKD1_k127_46552_19 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 354.0
HKD1_k127_46552_2 NADH ubiquinone plastoquinone (Complex I) - - - 4.043e-273 855.0
HKD1_k127_46552_20 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 360.0
HKD1_k127_46552_21 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 362.0
HKD1_k127_46552_22 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 333.0
HKD1_k127_46552_23 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 326.0
HKD1_k127_46552_24 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 324.0
HKD1_k127_46552_25 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 309.0
HKD1_k127_46552_26 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 305.0
HKD1_k127_46552_27 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 306.0
HKD1_k127_46552_28 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 292.0
HKD1_k127_46552_29 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009085 273.0
HKD1_k127_46552_3 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 4.985e-267 853.0
HKD1_k127_46552_30 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 276.0
HKD1_k127_46552_31 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 267.0
HKD1_k127_46552_32 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
HKD1_k127_46552_33 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000002367 235.0
HKD1_k127_46552_34 2-Keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000002659 240.0
HKD1_k127_46552_35 Helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000005843 206.0
HKD1_k127_46552_36 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000009974 187.0
HKD1_k127_46552_37 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000004435 183.0
HKD1_k127_46552_38 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000003296 169.0
HKD1_k127_46552_39 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000005782 131.0
HKD1_k127_46552_4 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 9.16e-231 734.0
HKD1_k127_46552_40 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000001724 124.0
HKD1_k127_46552_41 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000002532 91.0
HKD1_k127_46552_42 D-arabinono-1,4-lactone oxidase - - - 0.000000000000002128 89.0
HKD1_k127_46552_43 Protein of unknown function (DUF1223) - - - 0.00000000000005846 76.0
HKD1_k127_46552_45 DNA-sulfur modification-associated - - - 0.000004041 59.0
HKD1_k127_46552_46 (ABC) transporter - - - 0.000005854 55.0
HKD1_k127_46552_47 - - - - 0.00008729 50.0
HKD1_k127_46552_5 transport system fused permease components - - - 2.989e-224 716.0
HKD1_k127_46552_6 Metallopeptidase family M24 - - - 1.302e-209 661.0
HKD1_k127_46552_7 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 617.0
HKD1_k127_46552_8 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 573.0
HKD1_k127_46552_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 559.0
HKD1_k127_4684952_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 587.0
HKD1_k127_4684952_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 548.0
HKD1_k127_4684952_10 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000002827 73.0
HKD1_k127_4684952_11 addiction module antidote protein HigA K21498 - - 0.0000000001717 63.0
HKD1_k127_4684952_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 497.0
HKD1_k127_4684952_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 369.0
HKD1_k127_4684952_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004223 273.0
HKD1_k127_4684952_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 262.0
HKD1_k127_4684952_6 CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000001325 179.0
HKD1_k127_4684952_7 OsmC-like protein - - - 0.000000000000000000000000000000000000000000003155 177.0
HKD1_k127_4684952_8 Invasion gene expression up-regulator SirB - - - 0.0000000000000000000000000000000001488 139.0
HKD1_k127_4684952_9 Universal stress protein family - - - 0.0000000000000000000000000000376 123.0
HKD1_k127_4711824_0 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000001977 201.0
HKD1_k127_4711824_1 PEP-CTERM motif - - - 0.000000000000000000000000000281 121.0
HKD1_k127_4711824_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000007076 113.0
HKD1_k127_4711824_3 Parallel beta-helix repeats - - - 0.0000000003247 64.0
HKD1_k127_4711824_4 Transposase - - - 0.0000931 46.0
HKD1_k127_4743278_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 601.0
HKD1_k127_4743278_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 420.0
HKD1_k127_4743278_2 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 357.0
HKD1_k127_4743278_3 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 307.0
HKD1_k127_4743278_4 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000002067 230.0
HKD1_k127_476398_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 6.477e-315 985.0
HKD1_k127_476398_1 COG0474 Cation transport ATPase K01531 - 3.6.3.2 7.069e-284 897.0
HKD1_k127_476398_10 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000671 271.0
HKD1_k127_476398_11 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002039 258.0
HKD1_k127_476398_12 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001168 259.0
HKD1_k127_476398_13 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
HKD1_k127_476398_14 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001744 238.0
HKD1_k127_476398_15 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002181 238.0
HKD1_k127_476398_16 - - - - 0.0000000000000000000000000000000000000000000000000000000538 215.0
HKD1_k127_476398_17 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000002015 196.0
HKD1_k127_476398_18 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000001991 173.0
HKD1_k127_476398_19 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000002454 169.0
HKD1_k127_476398_2 heat shock protein binding - - - 4.312e-228 733.0
HKD1_k127_476398_20 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000000000007974 129.0
HKD1_k127_476398_21 Cytochrome C biogenesis K02200 - - 0.00000000000000000000146 104.0
HKD1_k127_476398_22 PIN domain - - - 0.000000000000000000001637 105.0
HKD1_k127_476398_23 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000002405 90.0
HKD1_k127_476398_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 625.0
HKD1_k127_476398_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 524.0
HKD1_k127_476398_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 486.0
HKD1_k127_476398_6 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 487.0
HKD1_k127_476398_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 355.0
HKD1_k127_476398_8 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 329.0
HKD1_k127_476398_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 323.0
HKD1_k127_4787059_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1210.0
HKD1_k127_4787059_1 dna topoisomerase III K03169 - 5.99.1.2 0.0 1103.0
HKD1_k127_4787059_10 TrkA-N domain protein K03499 - - 1.69e-197 625.0
HKD1_k127_4787059_11 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 618.0
HKD1_k127_4787059_12 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 603.0
HKD1_k127_4787059_13 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 576.0
HKD1_k127_4787059_14 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 554.0
HKD1_k127_4787059_15 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 496.0
HKD1_k127_4787059_16 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009989 452.0
HKD1_k127_4787059_17 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 435.0
HKD1_k127_4787059_18 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 424.0
HKD1_k127_4787059_19 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 419.0
HKD1_k127_4787059_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 9.668e-319 988.0
HKD1_k127_4787059_20 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 412.0
HKD1_k127_4787059_21 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 391.0
HKD1_k127_4787059_22 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 374.0
HKD1_k127_4787059_23 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 362.0
HKD1_k127_4787059_24 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 338.0
HKD1_k127_4787059_25 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 335.0
HKD1_k127_4787059_26 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000005352 229.0
HKD1_k127_4787059_27 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000003356 223.0
HKD1_k127_4787059_28 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000002267 204.0
HKD1_k127_4787059_29 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000000000129 190.0
HKD1_k127_4787059_3 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 9.583e-288 896.0
HKD1_k127_4787059_30 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000004147 183.0
HKD1_k127_4787059_31 signal peptide protein - - - 0.0000000000000000000000000000000000000000000002072 176.0
HKD1_k127_4787059_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000008491 171.0
HKD1_k127_4787059_33 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000001159 142.0
HKD1_k127_4787059_34 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000004537 148.0
HKD1_k127_4787059_35 Small membrane protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000009238 139.0
HKD1_k127_4787059_36 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000002597 111.0
HKD1_k127_4787059_37 ATP synthase I chain K02116 - - 0.00000000000000001533 93.0
HKD1_k127_4787059_38 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000001013 71.0
HKD1_k127_4787059_39 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000124 59.0
HKD1_k127_4787059_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.608e-278 862.0
HKD1_k127_4787059_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.834e-266 823.0
HKD1_k127_4787059_6 Methionine synthase K00548 - 2.1.1.13 1.276e-258 807.0
HKD1_k127_4787059_7 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 4.588e-227 726.0
HKD1_k127_4787059_8 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 5.77e-222 699.0
HKD1_k127_4787059_9 Belongs to the thiolase family K00626 - 2.3.1.9 7.152e-203 638.0
HKD1_k127_4798862_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.775e-279 867.0
HKD1_k127_4798862_1 Class II Aldolase and Adducin N-terminal domain - - - 2.029e-271 852.0
HKD1_k127_4798862_10 SmpB protein K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000002068 235.0
HKD1_k127_4798862_11 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000005227 242.0
HKD1_k127_4798862_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000002152 226.0
HKD1_k127_4798862_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000001551 172.0
HKD1_k127_4798862_14 ankyrin repeat K06867 - - 0.00000000000000000000000000000000000005808 158.0
HKD1_k127_4798862_15 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000003388 147.0
HKD1_k127_4798862_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000002347 151.0
HKD1_k127_4798862_17 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000741 92.0
HKD1_k127_4798862_18 Domain of unknown function (DUF4124) - - - 0.0000000000007718 76.0
HKD1_k127_4798862_19 Domain of unknown function (DUF4936) - - - 0.00000000001429 76.0
HKD1_k127_4798862_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.178e-241 754.0
HKD1_k127_4798862_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 511.0
HKD1_k127_4798862_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
HKD1_k127_4798862_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 385.0
HKD1_k127_4798862_6 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 334.0
HKD1_k127_4798862_7 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
HKD1_k127_4798862_8 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004699 255.0
HKD1_k127_4798862_9 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000008349 248.0
HKD1_k127_480921_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 561.0
HKD1_k127_480921_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 467.0
HKD1_k127_480921_2 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007547 297.0
HKD1_k127_480921_3 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000003099 236.0
HKD1_k127_4817211_0 CoA binding domain K09181 - - 9.446e-196 652.0
HKD1_k127_4817211_1 PFAM MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 532.0
HKD1_k127_4817211_2 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 407.0
HKD1_k127_4817211_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 348.0
HKD1_k127_4817211_4 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 332.0
HKD1_k127_4817211_5 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 320.0
HKD1_k127_4817211_6 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000114 227.0
HKD1_k127_4817211_7 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000004171 204.0
HKD1_k127_4873517_0 enoyl-CoA hydratase K15513 - 4.1.2.44 1.769e-250 785.0
HKD1_k127_4873517_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 6.414e-239 749.0
HKD1_k127_4873517_10 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 260.0
HKD1_k127_4873517_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000000000000000000000004406 235.0
HKD1_k127_4873517_12 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000009251 188.0
HKD1_k127_4873517_13 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000003447 180.0
HKD1_k127_4873517_14 cysteine dioxygenase - - - 0.0000000000000000000000000000000000000000000182 167.0
HKD1_k127_4873517_15 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000714 155.0
HKD1_k127_4873517_16 PFAM DoxX K15977 - - 0.0000000000000000000000000000000000001043 156.0
HKD1_k127_4873517_17 - - - - 0.00000000000000000000000000000003381 133.0
HKD1_k127_4873517_18 Putative regulatory protein - - - 0.0000000000000000004125 94.0
HKD1_k127_4873517_19 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.00000000008068 69.0
HKD1_k127_4873517_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 7.691e-218 714.0
HKD1_k127_4873517_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 602.0
HKD1_k127_4873517_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 611.0
HKD1_k127_4873517_5 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 462.0
HKD1_k127_4873517_6 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 391.0
HKD1_k127_4873517_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 375.0
HKD1_k127_4873517_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 344.0
HKD1_k127_4873517_9 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 338.0
HKD1_k127_4883261_0 Cupin - - - 0.000000000000000000000000000000000000000000000000002008 190.0
HKD1_k127_4883261_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000002948 189.0
HKD1_k127_4883261_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000008559 154.0
HKD1_k127_4912380_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000006692 209.0
HKD1_k127_4912380_1 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.000000000000000000000000000000008905 146.0
HKD1_k127_4948278_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 456.0
HKD1_k127_4948278_1 COGs COG5616 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 345.0
HKD1_k127_497131_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 488.0
HKD1_k127_497131_1 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000001263 98.0
HKD1_k127_5005542_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 374.0
HKD1_k127_5005542_1 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.00000000000000000000000000000000000000000000000000004012 190.0
HKD1_k127_5005542_2 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000007384 177.0
HKD1_k127_5005542_3 phosphatase (DUF442) - - - 0.00000000000000000000000000000000000003413 148.0
HKD1_k127_5005542_4 - - - - 0.0000000000000000000000000000000000009777 145.0
HKD1_k127_5005542_5 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000004207 125.0
HKD1_k127_5005542_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000159 106.0
HKD1_k127_5005542_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0001659 47.0
HKD1_k127_5027472_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000001598 168.0
HKD1_k127_5037801_0 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 591.0
HKD1_k127_5037801_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000001341 198.0
HKD1_k127_5037801_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000001874 188.0
HKD1_k127_5037801_3 membrane - - - 0.00000000000000001071 88.0
HKD1_k127_5051856_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.125e-235 737.0
HKD1_k127_5051856_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 2.067e-197 627.0
HKD1_k127_5051856_10 KR domain K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.0000000000000000000000000000000000000000000000000000000000000000000000000003389 269.0
HKD1_k127_5051856_11 MltA-interacting protein MipA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009633 247.0
HKD1_k127_5051856_12 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000004073 245.0
HKD1_k127_5051856_13 serine threonine protein kinase K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002339 198.0
HKD1_k127_5051856_14 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.00000000000000000000000000000000000000000000000009373 185.0
HKD1_k127_5051856_15 membrane - - - 0.00000000000000000000000000000000006899 137.0
HKD1_k127_5051856_16 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000007284 111.0
HKD1_k127_5051856_17 Protein of unknown function (DUF2905) - - - 0.000000000005396 69.0
HKD1_k127_5051856_18 -Thioesterase K01075 - 3.1.2.23 0.000000001066 67.0
HKD1_k127_5051856_2 Soluble lytic murein transglycosylase L domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 561.0
HKD1_k127_5051856_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
HKD1_k127_5051856_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 412.0
HKD1_k127_5051856_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 370.0
HKD1_k127_5051856_6 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 323.0
HKD1_k127_5051856_7 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 317.0
HKD1_k127_5051856_8 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
HKD1_k127_5051856_9 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 277.0
HKD1_k127_505244_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 323.0
HKD1_k127_505244_1 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
HKD1_k127_505244_2 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 284.0
HKD1_k127_505244_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000009978 77.0
HKD1_k127_5061740_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.528e-244 767.0
HKD1_k127_5061740_1 PFAM AMP-dependent synthetase and ligase K12508 - 6.2.1.34 9.924e-214 680.0
HKD1_k127_5061740_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 355.0
HKD1_k127_5061740_11 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 333.0
HKD1_k127_5061740_12 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 312.0
HKD1_k127_5061740_13 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
HKD1_k127_5061740_14 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001153 291.0
HKD1_k127_5061740_15 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 264.0
HKD1_k127_5061740_16 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003024 255.0
HKD1_k127_5061740_17 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000002745 202.0
HKD1_k127_5061740_18 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000005267 147.0
HKD1_k127_5061740_19 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000006548 122.0
HKD1_k127_5061740_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 576.0
HKD1_k127_5061740_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000002653 77.0
HKD1_k127_5061740_3 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 519.0
HKD1_k127_5061740_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 447.0
HKD1_k127_5061740_5 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 390.0
HKD1_k127_5061740_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 360.0
HKD1_k127_5061740_7 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 355.0
HKD1_k127_5061740_8 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 360.0
HKD1_k127_5061740_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 336.0
HKD1_k127_5066784_0 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 447.0
HKD1_k127_5066784_1 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 411.0
HKD1_k127_5066784_2 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 329.0
HKD1_k127_5066784_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 335.0
HKD1_k127_5066784_4 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 304.0
HKD1_k127_5066784_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000001918 66.0
HKD1_k127_5080296_0 Transporter - - - 1.395e-220 701.0
HKD1_k127_5080296_1 FAD binding domain K20940 - 1.14.13.218 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 585.0
HKD1_k127_5080296_10 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000002466 125.0
HKD1_k127_5080296_11 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000126 128.0
HKD1_k127_5080296_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000005796 107.0
HKD1_k127_5080296_2 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K20940 - 1.14.13.218 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 531.0
HKD1_k127_5080296_3 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 501.0
HKD1_k127_5080296_4 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 477.0
HKD1_k127_5080296_5 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 440.0
HKD1_k127_5080296_6 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 315.0
HKD1_k127_5080296_7 TRAP transporter solute receptor TAXI family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 304.0
HKD1_k127_5080296_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 292.0
HKD1_k127_5080296_9 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000002484 166.0
HKD1_k127_5105353_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1268.0
HKD1_k127_5105353_1 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 3.527e-285 889.0
HKD1_k127_5105353_10 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 312.0
HKD1_k127_5105353_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001006 254.0
HKD1_k127_5105353_12 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001239 251.0
HKD1_k127_5105353_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001576 251.0
HKD1_k127_5105353_14 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000003492 206.0
HKD1_k127_5105353_15 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000001383 177.0
HKD1_k127_5105353_16 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000001553 135.0
HKD1_k127_5105353_17 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000001219 93.0
HKD1_k127_5105353_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 6.106e-228 725.0
HKD1_k127_5105353_3 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 3.681e-219 684.0
HKD1_k127_5105353_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.777e-209 662.0
HKD1_k127_5105353_5 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 554.0
HKD1_k127_5105353_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 540.0
HKD1_k127_5105353_7 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 459.0
HKD1_k127_5105353_8 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 447.0
HKD1_k127_5105353_9 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
HKD1_k127_5165593_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 418.0
HKD1_k127_5165593_1 alpha/beta hydrolase fold - - - 0.0000000000000000002544 88.0
HKD1_k127_5165593_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000007331 75.0
HKD1_k127_5165593_3 Transposase and inactivated derivatives K07497 - - 0.0000292 51.0
HKD1_k127_5216581_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 469.0
HKD1_k127_5216581_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000114 57.0
HKD1_k127_5256654_0 SMART transcription factor jumonji jmjC domain protein K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 351.0
HKD1_k127_5256654_1 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000004624 225.0
HKD1_k127_5256654_2 VIT family - - - 0.000000000000000000000000000000000000000000005656 166.0
HKD1_k127_5256654_3 FKBP-type peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000004574 162.0
HKD1_k127_5256654_4 - - - - 0.0000000000000001487 91.0
HKD1_k127_5256654_5 ABC transporter, ATP-binding protein K02031 - - 0.00007302 46.0
HKD1_k127_5261887_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1266.0
HKD1_k127_5261887_1 Protein of unknown function (DUF3141) - - - 0.0 1040.0
HKD1_k127_5261887_10 COG4313 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 412.0
HKD1_k127_5261887_11 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 361.0
HKD1_k127_5261887_12 membrane - - - 0.000000000000000000000000000000000000000000000008523 192.0
HKD1_k127_5261887_13 Na( )-dependent transporter - - - 0.00000000000000000000000000000001095 139.0
HKD1_k127_5261887_14 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000002801 113.0
HKD1_k127_5261887_16 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0004124 52.0
HKD1_k127_5261887_2 Sulfate transporter K17470 - - 8.381e-204 647.0
HKD1_k127_5261887_3 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 574.0
HKD1_k127_5261887_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 534.0
HKD1_k127_5261887_5 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 497.0
HKD1_k127_5261887_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 442.0
HKD1_k127_5261887_7 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 424.0
HKD1_k127_5261887_8 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 420.0
HKD1_k127_5261887_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 428.0
HKD1_k127_5278927_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.733e-237 738.0
HKD1_k127_5278927_1 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000134 147.0
HKD1_k127_5278927_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000001535 102.0
HKD1_k127_5304431_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 2.803e-278 875.0
HKD1_k127_5304431_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 5.945e-276 868.0
HKD1_k127_5304431_10 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 358.0
HKD1_k127_5304431_11 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 320.0
HKD1_k127_5304431_13 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 291.0
HKD1_k127_5304431_14 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 293.0
HKD1_k127_5304431_15 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001362 308.0
HKD1_k127_5304431_16 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
HKD1_k127_5304431_17 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001364 275.0
HKD1_k127_5304431_18 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004534 277.0
HKD1_k127_5304431_19 luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001471 258.0
HKD1_k127_5304431_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 561.0
HKD1_k127_5304431_20 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001447 241.0
HKD1_k127_5304431_21 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006085 234.0
HKD1_k127_5304431_22 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000001875 240.0
HKD1_k127_5304431_23 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000002651 228.0
HKD1_k127_5304431_24 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.00000000000000000000000000000000000000000000000000000000005187 221.0
HKD1_k127_5304431_25 Beta-ketoacyl synthase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000005143 197.0
HKD1_k127_5304431_26 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000008691 189.0
HKD1_k127_5304431_27 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001498 204.0
HKD1_k127_5304431_28 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000718 195.0
HKD1_k127_5304431_29 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000009404 180.0
HKD1_k127_5304431_3 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 547.0
HKD1_k127_5304431_30 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000002484 174.0
HKD1_k127_5304431_31 dehydratase - - - 0.0000000000000000000000000000000001427 139.0
HKD1_k127_5304431_32 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000001971 135.0
HKD1_k127_5304431_33 TPR repeat - - - 0.000000000000000000000000000000005545 130.0
HKD1_k127_5304431_34 pathogenesis - - - 0.00000000000000000000000000002986 125.0
HKD1_k127_5304431_35 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000004387 114.0
HKD1_k127_5304431_36 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000001002 121.0
HKD1_k127_5304431_37 membrane - - - 0.000000000000002446 84.0
HKD1_k127_5304431_38 Fatty acyl CoA synthetase - - - 0.000000000000005969 83.0
HKD1_k127_5304431_39 dehydratase - - - 0.000000000003472 76.0
HKD1_k127_5304431_4 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 551.0
HKD1_k127_5304431_40 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0003084 50.0
HKD1_k127_5304431_5 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 484.0
HKD1_k127_5304431_6 Fumarate hydratase (Fumerase) K01677,K03779 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 459.0
HKD1_k127_5304431_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 448.0
HKD1_k127_5304431_8 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
HKD1_k127_5304431_9 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 375.0
HKD1_k127_5318630_0 Homospermidine synthase K00808 - 2.5.1.44 2.613e-226 709.0
HKD1_k127_5318630_1 Aminotransferase K14261 - - 2.201e-223 696.0
HKD1_k127_5318630_2 homoserine dehydrogenase K00003 - 1.1.1.3 1.551e-209 659.0
HKD1_k127_5318630_3 Threonine synthase K01733 - 4.2.3.1 6.057e-202 645.0
HKD1_k127_5318630_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 572.0
HKD1_k127_5318630_5 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 500.0
HKD1_k127_5318630_6 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 426.0
HKD1_k127_5318630_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 426.0
HKD1_k127_5318630_8 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000677 168.0
HKD1_k127_5318630_9 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000006223 118.0
HKD1_k127_5375761_0 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 531.0
HKD1_k127_5375761_1 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 466.0
HKD1_k127_5375761_2 Formyl transferase, C-terminal domain K19640 - - 0.0000000000000000000000000000000000000000000000003183 179.0
HKD1_k127_5399908_0 RES - - - 0.000000000000000000000000000000000000000000000000000000000025 211.0
HKD1_k127_5399908_1 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000000000000000008544 168.0
HKD1_k127_5399908_2 TonB C terminal - - - 0.00000000002754 63.0
HKD1_k127_5399908_3 Protein of unknown function (DUF3141) - - - 0.00003995 50.0
HKD1_k127_5410177_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000001717 195.0
HKD1_k127_5410177_1 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.0000000000000000000000000000000000000000000000002908 179.0
HKD1_k127_5410177_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000918 170.0
HKD1_k127_5410177_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000007662 154.0
HKD1_k127_5421695_0 Heat shock 70 kDa protein K04043 - - 7.56e-291 902.0
HKD1_k127_5421695_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 432.0
HKD1_k127_5421695_10 Protein of unknown function (DUF2934) - - - 0.00000001793 58.0
HKD1_k127_5421695_2 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 431.0
HKD1_k127_5421695_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000006927 270.0
HKD1_k127_5421695_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007523 267.0
HKD1_k127_5421695_5 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000004045 154.0
HKD1_k127_5421695_6 - - - - 0.0000000000000000000000000000001478 133.0
HKD1_k127_5421695_7 - - - - 0.000000000000000000000008041 102.0
HKD1_k127_5421695_8 - - - - 0.00000000000004117 79.0
HKD1_k127_5421695_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000001283 68.0
HKD1_k127_549394_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 581.0
HKD1_k127_549394_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000009548 132.0
HKD1_k127_549394_2 - - - - 0.00000000000000002774 87.0
HKD1_k127_5495449_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.513e-312 964.0
HKD1_k127_5495449_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.583e-290 910.0
HKD1_k127_5495449_2 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 336.0
HKD1_k127_5495449_3 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001833 252.0
HKD1_k127_5495449_4 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000002563 220.0
HKD1_k127_5495449_5 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000000000004603 120.0
HKD1_k127_5495449_6 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000001813 111.0
HKD1_k127_5495449_7 HupF/HypC family K04653 - - 0.00000000000000000000001213 103.0
HKD1_k127_5495449_8 Histidine kinase-like ATPase domain - - - 0.0000000000000000000005365 108.0
HKD1_k127_5588438_0 Histidine kinase K02484,K07639,K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000119 193.0
HKD1_k127_5588438_1 cytochrome c5 - - - 0.0000000000000000000000000000000000000000000009639 180.0
HKD1_k127_5588438_2 - - - - 0.00000000000000001571 95.0
HKD1_k127_5645761_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1046.0
HKD1_k127_5645761_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000009088 114.0
HKD1_k127_5658226_0 Amidohydrolase family - - - 1.503e-211 670.0
HKD1_k127_5658226_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 300.0
HKD1_k127_5658226_2 Diguanylate cyclase K21084 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000009134 224.0
HKD1_k127_5658226_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000006773 123.0
HKD1_k127_5737107_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 3.093e-308 951.0
HKD1_k127_5737107_1 PFAM Dimethylmenaquinone methyltransferase - - - 0.0000000000000000000000000000000666 144.0
HKD1_k127_5786341_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 4.281e-274 859.0
HKD1_k127_5786341_1 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 1.347e-265 826.0
HKD1_k127_5786341_10 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 531.0
HKD1_k127_5786341_11 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 522.0
HKD1_k127_5786341_12 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 488.0
HKD1_k127_5786341_13 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 495.0
HKD1_k127_5786341_14 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 487.0
HKD1_k127_5786341_15 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 486.0
HKD1_k127_5786341_16 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 462.0
HKD1_k127_5786341_17 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 449.0
HKD1_k127_5786341_18 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 439.0
HKD1_k127_5786341_19 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 431.0
HKD1_k127_5786341_2 Putative diguanylate phosphodiesterase - - - 1.011e-258 835.0
HKD1_k127_5786341_20 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 433.0
HKD1_k127_5786341_21 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 424.0
HKD1_k127_5786341_22 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 426.0
HKD1_k127_5786341_23 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 389.0
HKD1_k127_5786341_24 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 359.0
HKD1_k127_5786341_25 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 355.0
HKD1_k127_5786341_26 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 354.0
HKD1_k127_5786341_27 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 357.0
HKD1_k127_5786341_28 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 362.0
HKD1_k127_5786341_29 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 345.0
HKD1_k127_5786341_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.484e-213 670.0
HKD1_k127_5786341_30 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 352.0
HKD1_k127_5786341_31 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 297.0
HKD1_k127_5786341_32 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 293.0
HKD1_k127_5786341_33 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 290.0
HKD1_k127_5786341_34 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002335 288.0
HKD1_k127_5786341_35 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001048 271.0
HKD1_k127_5786341_36 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001545 282.0
HKD1_k127_5786341_37 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009415 273.0
HKD1_k127_5786341_38 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000008325 239.0
HKD1_k127_5786341_39 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186,K16875 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000005973 243.0
HKD1_k127_5786341_4 Belongs to the GMC oxidoreductase family - - - 2.11e-209 662.0
HKD1_k127_5786341_40 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000002595 215.0
HKD1_k127_5786341_41 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000003631 216.0
HKD1_k127_5786341_42 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000001481 215.0
HKD1_k127_5786341_43 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000002202 197.0
HKD1_k127_5786341_44 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000005113 179.0
HKD1_k127_5786341_45 - - - - 0.00000000000000000000000000000000000000009587 157.0
HKD1_k127_5786341_46 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000002146 150.0
HKD1_k127_5786341_47 Cysteine dioxygenase type I - - - 0.0000000000000000000000000000001366 141.0
HKD1_k127_5786341_48 MarR family - - - 0.00000000000000000000000000002564 123.0
HKD1_k127_5786341_49 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000003724 111.0
HKD1_k127_5786341_5 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 3.084e-209 666.0
HKD1_k127_5786341_50 - - - - 0.0000000000000000000001195 112.0
HKD1_k127_5786341_51 Protein of unknown function (DUF3301) - - - 0.000000000000000001089 98.0
HKD1_k127_5786341_53 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000003684 66.0
HKD1_k127_5786341_54 Protein of unknown function (DUF3567) - - - 0.0000000001766 65.0
HKD1_k127_5786341_6 Receptor family ligand binding region K01999 - - 8.947e-201 636.0
HKD1_k127_5786341_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 616.0
HKD1_k127_5786341_8 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 546.0
HKD1_k127_5786341_9 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 528.0
HKD1_k127_5831553_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 552.0
HKD1_k127_5831553_1 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 457.0
HKD1_k127_5831553_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 426.0
HKD1_k127_5831553_3 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 389.0
HKD1_k127_5831553_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 384.0
HKD1_k127_5831553_5 - - - - 0.0000000001443 63.0
HKD1_k127_597741_0 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 486.0
HKD1_k127_597741_1 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 325.0
HKD1_k127_597741_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 299.0
HKD1_k127_597741_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 275.0
HKD1_k127_597741_4 PFAM LemA K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007377 269.0
HKD1_k127_597741_5 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007472 259.0
HKD1_k127_597741_6 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000006624 234.0
HKD1_k127_597741_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000001539 160.0
HKD1_k127_597741_8 serine threonine protein kinase - - - 0.0000000000000000000000000000001545 130.0
HKD1_k127_597741_9 Pfam:TPM - - - 0.00000000000000000000000000009969 124.0
HKD1_k127_6044796_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 524.0
HKD1_k127_6044796_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 385.0
HKD1_k127_6044796_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 380.0
HKD1_k127_6044796_3 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 324.0
HKD1_k127_6044796_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 301.0
HKD1_k127_6044796_5 branched-chain amino acid transport K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 323.0
HKD1_k127_6044796_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000006647 229.0
HKD1_k127_6044796_7 Thioesterase - - - 0.000000000000000000000000000000000000000000005833 169.0
HKD1_k127_6058938_0 ammonium transporter K03320,K06580 - - 6.665e-213 672.0
HKD1_k127_6058938_1 AMP-binding enzyme K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 594.0
HKD1_k127_6058938_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 305.0
HKD1_k127_6058938_3 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006272 251.0
HKD1_k127_6058938_4 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000004473 231.0
HKD1_k127_6058938_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000008366 131.0
HKD1_k127_6066622_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 6.813e-267 852.0
HKD1_k127_6066622_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 371.0
HKD1_k127_6066622_10 cytochrome c5 - - - 0.000000000000000000000000000000000000000000000000006362 194.0
HKD1_k127_6066622_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000001656 126.0
HKD1_k127_6066622_12 Cytochrome c - - - 0.000000000000000000000003713 115.0
HKD1_k127_6066622_13 COG2829 Outer membrane phospholipase A K01058 - 3.1.1.32,3.1.1.4 0.00000000003666 63.0
HKD1_k127_6066622_2 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 356.0
HKD1_k127_6066622_3 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 331.0
HKD1_k127_6066622_4 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 327.0
HKD1_k127_6066622_5 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 291.0
HKD1_k127_6066622_6 Member of a two-component regulatory system K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007309 273.0
HKD1_k127_6066622_7 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000004771 224.0
HKD1_k127_6066622_8 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000001167 207.0
HKD1_k127_6066622_9 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000002038 208.0
HKD1_k127_6068872_0 Protein of unknown function (DUF3141) - - - 9.333e-320 996.0
HKD1_k127_6068872_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 1.972e-249 778.0
HKD1_k127_6068872_2 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000002367 235.0
HKD1_k127_6068872_3 - - - - 0.000000000000000000000000000000000000000000000000000000000004548 211.0
HKD1_k127_6068872_4 - - - - 0.000000000000000000000000000000000000000000007306 165.0
HKD1_k127_6068872_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000002531 90.0
HKD1_k127_6101038_0 Sulfatase K01130 - 3.1.6.1 2.02e-274 855.0
HKD1_k127_6101038_1 Transmembrane secretion effector - - - 1.515e-221 716.0
HKD1_k127_6101038_10 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002688 278.0
HKD1_k127_6101038_11 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002234 259.0
HKD1_k127_6101038_12 Ceramidase - - - 0.0000000000000000000000000000000000000000000000000000000001042 214.0
HKD1_k127_6101038_13 GNAT family acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000008375 201.0
HKD1_k127_6101038_14 - - - - 0.000000000000000000000000000000000000000000000000000003137 196.0
HKD1_k127_6101038_15 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000009467 180.0
HKD1_k127_6101038_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000006338 177.0
HKD1_k127_6101038_17 - - - - 0.0000000000000000000000000000000000001914 149.0
HKD1_k127_6101038_18 HNH nucleases - - - 0.00000000000000000000000000000004587 145.0
HKD1_k127_6101038_19 CoA binding domain K09181 - - 0.000000000000000000145 94.0
HKD1_k127_6101038_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 617.0
HKD1_k127_6101038_20 - - - - 0.00000000000000004746 84.0
HKD1_k127_6101038_21 response regulator - - - 0.0000000000009162 72.0
HKD1_k127_6101038_22 domain, Protein K02674 - - 0.00000003971 66.0
HKD1_k127_6101038_24 Acyl CoA binding protein - - - 0.00002349 57.0
HKD1_k127_6101038_3 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 516.0
HKD1_k127_6101038_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 506.0
HKD1_k127_6101038_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 437.0
HKD1_k127_6101038_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 351.0
HKD1_k127_6101038_7 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 346.0
HKD1_k127_6101038_8 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 307.0
HKD1_k127_6101038_9 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 305.0
HKD1_k127_6101765_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 7.832e-308 957.0
HKD1_k127_6101765_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 1.528e-297 929.0
HKD1_k127_6101765_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 328.0
HKD1_k127_6101765_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 321.0
HKD1_k127_6101765_12 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 328.0
HKD1_k127_6101765_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 296.0
HKD1_k127_6101765_14 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 304.0
HKD1_k127_6101765_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 294.0
HKD1_k127_6101765_16 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
HKD1_k127_6101765_17 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004912 266.0
HKD1_k127_6101765_18 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000001239 253.0
HKD1_k127_6101765_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000172 253.0
HKD1_k127_6101765_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.988e-249 775.0
HKD1_k127_6101765_20 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
HKD1_k127_6101765_21 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000183 240.0
HKD1_k127_6101765_22 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000003299 205.0
HKD1_k127_6101765_23 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000001924 204.0
HKD1_k127_6101765_24 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000003346 159.0
HKD1_k127_6101765_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000001505 164.0
HKD1_k127_6101765_26 Fumarate reductase subunit C - - - 0.00000000000000000000000000000003463 137.0
HKD1_k127_6101765_27 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000001017 112.0
HKD1_k127_6101765_28 Fumarate reductase subunit D - - - 0.00000000000000002953 87.0
HKD1_k127_6101765_29 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000009078 57.0
HKD1_k127_6101765_3 Fumarate reductase flavoprotein C-term - - - 1.59e-248 779.0
HKD1_k127_6101765_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.887e-231 721.0
HKD1_k127_6101765_5 chain 5 L K00341 - 1.6.5.3 2.414e-207 651.0
HKD1_k127_6101765_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 523.0
HKD1_k127_6101765_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 381.0
HKD1_k127_6101765_8 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 334.0
HKD1_k127_6101765_9 TIGRFAM decaheme c-type cytochrome, DmsE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 334.0
HKD1_k127_6107737_0 Serine threonine protein kinase - - - 6.27e-207 646.0
HKD1_k127_6107737_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 356.0
HKD1_k127_6107737_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 355.0
HKD1_k127_6107737_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000009667 78.0
HKD1_k127_6107737_4 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000007373 85.0
HKD1_k127_6120819_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002158 249.0
HKD1_k127_6120819_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000009262 221.0
HKD1_k127_6120819_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000001042 114.0
HKD1_k127_6163014_0 Acyclic terpene utilisation family protein AtuA - - - 1.346e-236 738.0
HKD1_k127_6163014_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 385.0
HKD1_k127_6163014_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 323.0
HKD1_k127_6163014_3 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000006509 246.0
HKD1_k127_6163014_4 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000001011 212.0
HKD1_k127_6163014_5 Domain of unknown function (DUF4387) - - - 0.000000000000000000000000000000000000000000000006067 173.0
HKD1_k127_6163014_6 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000002866 179.0
HKD1_k127_6163014_7 Integrase core domain - - - 0.000000000000000000000001108 104.0
HKD1_k127_6168355_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 9.786e-241 764.0
HKD1_k127_6168355_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 439.0
HKD1_k127_6168355_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000001043 154.0
HKD1_k127_6174830_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 465.0
HKD1_k127_6174830_1 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 320.0
HKD1_k127_6174830_2 dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007016 232.0
HKD1_k127_6174830_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000001314 171.0
HKD1_k127_6174830_4 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000555 168.0
HKD1_k127_6174830_5 Universal stress protein family - - - 0.0000000000000000000000000000000000239 140.0
HKD1_k127_6174830_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000003465 132.0
HKD1_k127_6174830_7 HNH endonuclease - - - 0.000000000000000000000000001809 114.0
HKD1_k127_6183181_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 488.0
HKD1_k127_6183181_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 457.0
HKD1_k127_6183181_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 398.0
HKD1_k127_6183181_3 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006323 242.0
HKD1_k127_6183181_4 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000008105 235.0
HKD1_k127_6183181_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001704 240.0
HKD1_k127_6183181_6 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000893 139.0
HKD1_k127_6183181_7 Protein of unknown function (DUF3306) - - - 0.000000000004935 79.0
HKD1_k127_6187269_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.122e-262 825.0
HKD1_k127_6187269_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.203e-195 623.0
HKD1_k127_6187269_10 - - - - 0.000000000000000000000000000000000000004134 152.0
HKD1_k127_6187269_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000001116 137.0
HKD1_k127_6187269_12 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000000001232 95.0
HKD1_k127_6187269_13 Serine aminopeptidase, S33 - - - 0.0000000000000887 73.0
HKD1_k127_6187269_14 - - - - 0.000000000008049 69.0
HKD1_k127_6187269_15 AsmA family K07289,K07290 - - 0.00000001134 69.0
HKD1_k127_6187269_2 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 587.0
HKD1_k127_6187269_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 541.0
HKD1_k127_6187269_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 511.0
HKD1_k127_6187269_5 surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 425.0
HKD1_k127_6187269_6 protein conserved in bacteria K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 424.0
HKD1_k127_6187269_7 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003725 308.0
HKD1_k127_6187269_8 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000003722 213.0
HKD1_k127_6187269_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000007225 206.0
HKD1_k127_6201313_0 FAD binding domain K00480 - 1.14.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 549.0
HKD1_k127_6201313_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000506 86.0
HKD1_k127_6201313_2 - - - - 0.00001094 48.0
HKD1_k127_6201313_3 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.0008496 48.0
HKD1_k127_6204439_0 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 608.0
HKD1_k127_6204439_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000003526 117.0
HKD1_k127_6204439_2 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000231 122.0
HKD1_k127_6206870_0 pfam abc - - - 9.745e-242 758.0
HKD1_k127_6206870_1 D-aminoacylase domain protein K06015 - 3.5.1.81 1.072e-219 690.0
HKD1_k127_6206870_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000001773 159.0
HKD1_k127_6206870_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000002273 147.0
HKD1_k127_6206870_12 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000003596 140.0
HKD1_k127_6206870_13 - - - - 0.00000000000000000000000000002832 120.0
HKD1_k127_6206870_14 SMART Cold shock protein K03704 - - 0.00000000000000000000000000003678 117.0
HKD1_k127_6206870_15 Cytochrome - - - 0.000007389 48.0
HKD1_k127_6206870_2 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 391.0
HKD1_k127_6206870_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 336.0
HKD1_k127_6206870_4 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 329.0
HKD1_k127_6206870_5 PFAM response regulator receiver K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 306.0
HKD1_k127_6206870_6 NAD-dependent epimerase dehydratase K18981 - 1.1.1.203 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 297.0
HKD1_k127_6206870_7 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000006958 225.0
HKD1_k127_6206870_8 Putative metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000003015 210.0
HKD1_k127_6206870_9 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000000001198 215.0
HKD1_k127_6224553_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 6.184e-259 809.0
HKD1_k127_6224553_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.886e-196 625.0
HKD1_k127_6224553_2 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 373.0
HKD1_k127_6224553_3 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006785 261.0
HKD1_k127_6224553_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001156 233.0
HKD1_k127_6224553_5 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000000000000000001238 214.0
HKD1_k127_6224553_6 ferredoxin - - - 0.00000000000000000000000000000000000001491 144.0
HKD1_k127_6224553_7 Hemerythrin HHE cation binding domain - - - 0.00000000000000000002479 106.0
HKD1_k127_6234730_0 AcyL-CoA dehydrogenase K06445 - - 7e-323 1007.0
HKD1_k127_6234730_1 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.394e-232 741.0
HKD1_k127_6234730_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 400.0
HKD1_k127_6234730_11 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006041 289.0
HKD1_k127_6234730_12 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005096 259.0
HKD1_k127_6234730_13 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001156 239.0
HKD1_k127_6234730_14 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 243.0
HKD1_k127_6234730_15 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000001723 234.0
HKD1_k127_6234730_16 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000003279 218.0
HKD1_k127_6234730_17 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000000002531 181.0
HKD1_k127_6234730_18 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000005049 183.0
HKD1_k127_6234730_19 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.00000000000000000000000000000000000004891 150.0
HKD1_k127_6234730_2 Belongs to the thiolase family K00626 - 2.3.1.9 2.197e-201 640.0
HKD1_k127_6234730_20 Protein of unknown function (DUF465) - - - 0.00000000000006419 75.0
HKD1_k127_6234730_21 NUDIX hydrolase - - - 0.0000001654 61.0
HKD1_k127_6234730_22 endonuclease exonuclease phosphatase - - - 0.0000001829 55.0
HKD1_k127_6234730_23 Protein of unknown function (DUF2917) - - - 0.0000143 51.0
HKD1_k127_6234730_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 6.255e-198 623.0
HKD1_k127_6234730_4 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 514.0
HKD1_k127_6234730_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 511.0
HKD1_k127_6234730_6 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 451.0
HKD1_k127_6234730_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 435.0
HKD1_k127_6234730_8 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 411.0
HKD1_k127_6234730_9 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 409.0
HKD1_k127_6290618_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 521.0
HKD1_k127_6290618_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 518.0
HKD1_k127_6290618_10 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 322.0
HKD1_k127_6290618_11 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 319.0
HKD1_k127_6290618_12 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 316.0
HKD1_k127_6290618_13 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 310.0
HKD1_k127_6290618_14 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004021 282.0
HKD1_k127_6290618_15 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
HKD1_k127_6290618_16 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004642 244.0
HKD1_k127_6290618_17 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000003618 211.0
HKD1_k127_6290618_18 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000005648 160.0
HKD1_k127_6290618_19 RDD family - - - 0.000000000000000000000000000000000000009939 149.0
HKD1_k127_6290618_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 476.0
HKD1_k127_6290618_20 Thioesterase superfamily protein - - - 0.0000000000000000000001439 109.0
HKD1_k127_6290618_21 Phosphopantetheine attachment site - - - 0.0000000000000000000003461 109.0
HKD1_k127_6290618_22 Domain of unknown function (DUF4124) - - - 0.000001851 55.0
HKD1_k127_6290618_3 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 453.0
HKD1_k127_6290618_4 13-prostaglandin reductase activity K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 393.0
HKD1_k127_6290618_5 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 389.0
HKD1_k127_6290618_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 358.0
HKD1_k127_6290618_7 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 355.0
HKD1_k127_6290618_8 ABC transporter substrate-binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 355.0
HKD1_k127_6290618_9 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 336.0
HKD1_k127_6295100_0 E1 component K00164 - 1.2.4.2 0.0 1322.0
HKD1_k127_6295100_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1056.0
HKD1_k127_6295100_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 574.0
HKD1_k127_6295100_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 561.0
HKD1_k127_6295100_12 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 488.0
HKD1_k127_6295100_13 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 496.0
HKD1_k127_6295100_14 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 473.0
HKD1_k127_6295100_15 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 432.0
HKD1_k127_6295100_16 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 432.0
HKD1_k127_6295100_17 PFAM AFG1-family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 421.0
HKD1_k127_6295100_18 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 399.0
HKD1_k127_6295100_19 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 322.0
HKD1_k127_6295100_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 5.228e-305 951.0
HKD1_k127_6295100_20 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 285.0
HKD1_k127_6295100_21 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005061 284.0
HKD1_k127_6295100_22 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000008457 162.0
HKD1_k127_6295100_23 Thioredoxin-like - - - 0.00000000000000000000000000000000000000004403 158.0
HKD1_k127_6295100_24 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.0000000000000000000000000000000000005882 141.0
HKD1_k127_6295100_25 Succinate dehydrogenase, hydrophobic K00242 - - 0.00000000000000000000000000000000000357 143.0
HKD1_k127_6295100_26 Haem-degrading - - - 0.0000000000000000000000000000002643 144.0
HKD1_k127_6295100_27 PspC domain - - - 0.000000000000000000000000000001802 123.0
HKD1_k127_6295100_28 succinate dehydrogenase K00241 - - 0.0000000000000000000000000007599 121.0
HKD1_k127_6295100_29 - - - - 0.000000000000000000000000007515 110.0
HKD1_k127_6295100_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 6.273e-304 942.0
HKD1_k127_6295100_30 - - - - 0.0000000000000001449 83.0
HKD1_k127_6295100_31 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000004912 77.0
HKD1_k127_6295100_33 - - - - 0.0000000000005527 68.0
HKD1_k127_6295100_34 Protein of unknown function (DUF3460) - - - 0.00000000006934 64.0
HKD1_k127_6295100_36 - - - - 0.0000003388 51.0
HKD1_k127_6295100_4 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.725e-262 828.0
HKD1_k127_6295100_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.563e-261 812.0
HKD1_k127_6295100_6 2-methylcitrate dehydratase K01720 - 4.2.1.79 4.795e-257 801.0
HKD1_k127_6295100_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.254e-234 730.0
HKD1_k127_6295100_8 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 3.32e-206 650.0
HKD1_k127_6295100_9 Belongs to the citrate synthase family K01659 - 2.3.3.5 4.066e-198 626.0
HKD1_k127_6315642_0 Amidohydrolase family K01464 - 3.5.2.2 3.033e-225 718.0
HKD1_k127_6315642_1 ABC-type branched-chain amino acid transport systems periplasmic component K11959 - - 8.232e-221 694.0
HKD1_k127_6315642_10 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000001189 181.0
HKD1_k127_6315642_11 PFAM CBS domain containing protein - - - 0.000000000000003003 78.0
HKD1_k127_6315642_2 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 573.0
HKD1_k127_6315642_3 Branched-chain amino acid transport system / permease component K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 518.0
HKD1_k127_6315642_4 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 403.0
HKD1_k127_6315642_5 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 407.0
HKD1_k127_6315642_6 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 381.0
HKD1_k127_6315642_7 ABC transporter K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 359.0
HKD1_k127_6315642_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 308.0
HKD1_k127_6315642_9 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000007075 176.0
HKD1_k127_6317639_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.208e-318 984.0
HKD1_k127_6317639_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.035e-270 841.0
HKD1_k127_6317639_2 CobB/CobQ-like glutamine amidotransferase domain K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 586.0
HKD1_k127_6317639_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 508.0
HKD1_k127_6317639_4 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 478.0
HKD1_k127_6317639_5 Fe-S oxidoreductase K21834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 413.0
HKD1_k127_6317639_6 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 357.0
HKD1_k127_6317639_7 - - - - 0.0000000000000000000000000007003 117.0
HKD1_k127_6317639_8 diguanylate cyclase - - - 0.000001438 50.0
HKD1_k127_6317639_9 Iron-sulphur cluster biosynthesis K13628 - - 0.00002238 53.0
HKD1_k127_634283_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 358.0
HKD1_k127_634283_1 Belongs to the ABC transporter superfamily K02032,K12372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003918 263.0
HKD1_k127_634283_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000004914 217.0
HKD1_k127_6389188_0 Putative beta-barrel porin 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000005876 239.0
HKD1_k127_6389188_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000009625 198.0
HKD1_k127_6389188_2 - - - - 0.0000000000000000003696 92.0
HKD1_k127_6390235_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 3.134e-272 850.0
HKD1_k127_6390235_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.527e-206 647.0
HKD1_k127_6390235_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 519.0
HKD1_k127_6390235_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000002998 226.0
HKD1_k127_6390235_4 LysR substrate binding domain K03717 - - 0.0000001051 57.0
HKD1_k127_6460923_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 580.0
HKD1_k127_6460923_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 394.0
HKD1_k127_6460923_10 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000005407 190.0
HKD1_k127_6460923_11 - - - - 0.0000000000000000000000000000000000000000004125 168.0
HKD1_k127_6460923_12 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000006983 157.0
HKD1_k127_6460923_13 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000001364 149.0
HKD1_k127_6460923_14 Pfam:DUF59 - - - 0.000000000000000000000000009627 112.0
HKD1_k127_6460923_15 Gram-negative porin K03285 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000001607 101.0
HKD1_k127_6460923_16 PFAM porin Gram-negative type K03285 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000004103 84.0
HKD1_k127_6460923_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 391.0
HKD1_k127_6460923_3 PFAM aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 384.0
HKD1_k127_6460923_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 372.0
HKD1_k127_6460923_5 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
HKD1_k127_6460923_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000005088 239.0
HKD1_k127_6460923_7 regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000002097 228.0
HKD1_k127_6460923_8 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000001149 214.0
HKD1_k127_6460923_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000007082 207.0
HKD1_k127_6475675_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 443.0
HKD1_k127_6475675_1 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 293.0
HKD1_k127_6475675_2 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000001255 183.0
HKD1_k127_6475675_3 C-lobe and N-lobe beta barrels of Tf-binding protein B - - - 0.000000000000000000000000000000000000000000003549 176.0
HKD1_k127_6521926_0 UPF0313 protein - - - 0.0 1080.0
HKD1_k127_6521926_1 Fumarate reductase flavoprotein C-term - - - 4.109e-208 648.0
HKD1_k127_6521926_10 reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 312.0
HKD1_k127_6521926_11 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 317.0
HKD1_k127_6521926_12 Histidine kinase K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 333.0
HKD1_k127_6521926_13 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006004 254.0
HKD1_k127_6521926_14 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002311 248.0
HKD1_k127_6521926_15 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000005761 213.0
HKD1_k127_6521926_16 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000001197 192.0
HKD1_k127_6521926_17 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000003688 151.0
HKD1_k127_6521926_18 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.00000001519 59.0
HKD1_k127_6521926_19 - - - - 0.0000006066 51.0
HKD1_k127_6521926_2 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 594.0
HKD1_k127_6521926_20 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.0001255 52.0
HKD1_k127_6521926_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 516.0
HKD1_k127_6521926_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 473.0
HKD1_k127_6521926_5 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 418.0
HKD1_k127_6521926_6 response regulator K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 362.0
HKD1_k127_6521926_7 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 326.0
HKD1_k127_6521926_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
HKD1_k127_6521926_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 331.0
HKD1_k127_6563254_0 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 440.0
HKD1_k127_6563254_1 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
HKD1_k127_6563254_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000003222 118.0
HKD1_k127_6563254_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K11389 - 1.2.7.5,1.2.7.6 0.000000000000000003107 93.0
HKD1_k127_6583277_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1480.0
HKD1_k127_6583277_1 Malic enzyme K00029 - 1.1.1.40 0.0 1073.0
HKD1_k127_6583277_10 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 555.0
HKD1_k127_6583277_11 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 529.0
HKD1_k127_6583277_12 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 492.0
HKD1_k127_6583277_13 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 490.0
HKD1_k127_6583277_14 PFAM aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 439.0
HKD1_k127_6583277_15 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 430.0
HKD1_k127_6583277_16 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 404.0
HKD1_k127_6583277_17 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 370.0
HKD1_k127_6583277_18 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 289.0
HKD1_k127_6583277_19 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 310.0
HKD1_k127_6583277_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1016.0
HKD1_k127_6583277_20 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008969 278.0
HKD1_k127_6583277_21 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001532 276.0
HKD1_k127_6583277_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000013 276.0
HKD1_k127_6583277_23 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005542 261.0
HKD1_k127_6583277_24 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 255.0
HKD1_k127_6583277_25 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002141 255.0
HKD1_k127_6583277_26 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 256.0
HKD1_k127_6583277_27 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005313 246.0
HKD1_k127_6583277_28 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000001462 245.0
HKD1_k127_6583277_29 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000003227 241.0
HKD1_k127_6583277_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 7.782e-292 915.0
HKD1_k127_6583277_30 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000002173 190.0
HKD1_k127_6583277_31 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000000000000000000000001539 184.0
HKD1_k127_6583277_32 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000001947 188.0
HKD1_k127_6583277_33 PFAM regulatory protein MerR - - - 0.00000000000000000000000000000000000000000000000003471 181.0
HKD1_k127_6583277_34 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000004812 171.0
HKD1_k127_6583277_35 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000002151 158.0
HKD1_k127_6583277_36 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000001303 158.0
HKD1_k127_6583277_37 CNP1-like family - - - 0.0000000000000000000000000000000008745 138.0
HKD1_k127_6583277_38 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000023 130.0
HKD1_k127_6583277_39 Ribosomal protein L35 K02916 - - 0.0000000000000000006041 87.0
HKD1_k127_6583277_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.233e-270 846.0
HKD1_k127_6583277_40 - K06950 - - 0.00000000001051 67.0
HKD1_k127_6583277_41 Protein of unknown function (DUF2442) - - - 0.0000000118 66.0
HKD1_k127_6583277_42 Histone H1-like nucleoprotein HC2 K11275 - - 0.00000008294 59.0
HKD1_k127_6583277_5 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.415e-256 802.0
HKD1_k127_6583277_6 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.008e-211 661.0
HKD1_k127_6583277_7 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 581.0
HKD1_k127_6583277_8 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 549.0
HKD1_k127_6583277_9 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 530.0
HKD1_k127_6662422_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.38e-295 912.0
HKD1_k127_6662422_1 protein synthesis factor, GTP-binding K06207 - - 6.938e-293 913.0
HKD1_k127_6662422_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 440.0
HKD1_k127_6662422_11 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 452.0
HKD1_k127_6662422_12 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 445.0
HKD1_k127_6662422_13 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 439.0
HKD1_k127_6662422_14 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 419.0
HKD1_k127_6662422_15 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 396.0
HKD1_k127_6662422_16 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 401.0
HKD1_k127_6662422_17 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 374.0
HKD1_k127_6662422_18 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 382.0
HKD1_k127_6662422_19 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 378.0
HKD1_k127_6662422_2 PFAM AMP-dependent synthetase K01895 - 6.2.1.1 6.24e-260 819.0
HKD1_k127_6662422_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 383.0
HKD1_k127_6662422_21 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 359.0
HKD1_k127_6662422_22 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 352.0
HKD1_k127_6662422_23 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 342.0
HKD1_k127_6662422_24 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 325.0
HKD1_k127_6662422_25 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 323.0
HKD1_k127_6662422_26 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005488 278.0
HKD1_k127_6662422_27 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005588 287.0
HKD1_k127_6662422_28 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004811 267.0
HKD1_k127_6662422_29 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000002232 263.0
HKD1_k127_6662422_3 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.15e-231 737.0
HKD1_k127_6662422_30 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002742 257.0
HKD1_k127_6662422_31 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000000236 244.0
HKD1_k127_6662422_32 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003539 246.0
HKD1_k127_6662422_33 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
HKD1_k127_6662422_34 Pyrimidine 5''-nucleotidase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000004596 253.0
HKD1_k127_6662422_35 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000308 228.0
HKD1_k127_6662422_36 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
HKD1_k127_6662422_37 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000009543 233.0
HKD1_k127_6662422_38 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000002775 220.0
HKD1_k127_6662422_39 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000495 201.0
HKD1_k127_6662422_4 Peptidase M1 membrane alanine aminopeptidase - - - 4.018e-223 715.0
HKD1_k127_6662422_40 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000985 192.0
HKD1_k127_6662422_41 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000001954 187.0
HKD1_k127_6662422_42 transcriptional - - - 0.0000000000000000000000000000000000000000000004251 168.0
HKD1_k127_6662422_43 signal sequence binding - - - 0.000000000000000000000000000000000000000001232 168.0
HKD1_k127_6662422_44 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000007998 158.0
HKD1_k127_6662422_45 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000004221 147.0
HKD1_k127_6662422_46 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000001002 151.0
HKD1_k127_6662422_47 Bacterial SH3 domain - - - 0.000000000000000000000000000000006293 139.0
HKD1_k127_6662422_48 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000002268 137.0
HKD1_k127_6662422_49 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000001853 124.0
HKD1_k127_6662422_5 Bacterial protein of unknown function (DUF853) K06915 - - 1.897e-219 690.0
HKD1_k127_6662422_50 Integral membrane protein (DUF2244) - - - 0.000000000000000166 87.0
HKD1_k127_6662422_51 Protein of unknown function (DUF2909) - - - 0.00000000001686 71.0
HKD1_k127_6662422_52 Glycine zipper 2TM domain - - - 0.000000005776 64.0
HKD1_k127_6662422_53 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000005396 57.0
HKD1_k127_6662422_54 Protein of unknown function (DUF2970) - - - 0.00002447 55.0
HKD1_k127_6662422_55 - - - - 0.0001917 53.0
HKD1_k127_6662422_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 591.0
HKD1_k127_6662422_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 554.0
HKD1_k127_6662422_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 548.0
HKD1_k127_6662422_9 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 501.0
HKD1_k127_6683417_0 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000002475 173.0
HKD1_k127_6683417_1 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000000000000000000000000000000000002379 156.0
HKD1_k127_6796478_0 peptidase, M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 610.0
HKD1_k127_6796478_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 347.0
HKD1_k127_6796478_2 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005185 290.0
HKD1_k127_6796478_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001854 242.0
HKD1_k127_6796478_4 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000009328 188.0
HKD1_k127_6796478_5 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000004337 162.0
HKD1_k127_681215_0 - - - - 5.506e-202 646.0
HKD1_k127_681215_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 411.0
HKD1_k127_681215_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004122 243.0
HKD1_k127_681215_3 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000000009012 149.0
HKD1_k127_681215_4 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000001114 151.0
HKD1_k127_6912724_0 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 0.0 1185.0
HKD1_k127_6912724_1 Amino acid permease K03756 - - 3.691e-300 937.0
HKD1_k127_6912724_2 Arginine K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 432.0
HKD1_k127_6933642_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1423.0
HKD1_k127_6933642_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.54e-207 674.0
HKD1_k127_6933642_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 328.0
HKD1_k127_6933642_3 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 298.0
HKD1_k127_6933642_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000006707 205.0
HKD1_k127_6933642_5 Protein of unknown function (DUF3240) - - - 0.0000000001013 76.0
HKD1_k127_6933642_6 methyl-accepting chemotaxis protein - - - 0.000001425 55.0
HKD1_k127_7044950_0 - - - - 0.0000000000000000000000000000000000000000000000000000000001746 207.0
HKD1_k127_7044950_1 transcriptional regulator PadR family - - - 0.0000000000000000000000002042 110.0
HKD1_k127_7044950_2 - - - - 0.000000000000000001345 89.0
HKD1_k127_7044950_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.0003039 45.0
HKD1_k127_7047527_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1147.0
HKD1_k127_7047527_1 Belongs to the TPP enzyme family K01577 - 4.1.1.8 1.413e-315 973.0
HKD1_k127_7047527_10 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 353.0
HKD1_k127_7047527_11 (FHA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 312.0
HKD1_k127_7047527_12 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 319.0
HKD1_k127_7047527_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000002892 237.0
HKD1_k127_7047527_14 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000001089 230.0
HKD1_k127_7047527_15 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000005661 191.0
HKD1_k127_7047527_16 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.000000000000000000000000000000000000000009832 158.0
HKD1_k127_7047527_17 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.00000000000000000000000000000000000008971 147.0
HKD1_k127_7047527_18 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000001278 146.0
HKD1_k127_7047527_19 membrane protein (DUF2079) - - - 0.0000000000000000000000000000001366 142.0
HKD1_k127_7047527_2 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 2.25e-261 816.0
HKD1_k127_7047527_20 oligosaccharyl transferase activity - - - 0.000000000000000000000001232 120.0
HKD1_k127_7047527_21 polysaccharide biosynthetic process K00655,K00721 - 2.3.1.51,2.4.1.83 0.000000000001702 73.0
HKD1_k127_7047527_22 Methyltransferase small domain - - - 0.0000001351 62.0
HKD1_k127_7047527_23 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000004663 51.0
HKD1_k127_7047527_3 metal-dependent phosphohydrolase HD sub domain - - - 3.506e-241 757.0
HKD1_k127_7047527_4 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 589.0
HKD1_k127_7047527_5 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 450.0
HKD1_k127_7047527_6 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 443.0
HKD1_k127_7047527_7 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 440.0
HKD1_k127_7047527_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 437.0
HKD1_k127_7047527_9 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 370.0
HKD1_k127_7052236_0 ATPase (P-type) K01535 - 3.6.3.6 5.646e-285 894.0
HKD1_k127_7052236_1 Peptidase family M41 K03798 - - 2.981e-255 801.0
HKD1_k127_7052236_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000004652 96.0
HKD1_k127_7052236_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 3.225e-248 774.0
HKD1_k127_7052236_3 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 618.0
HKD1_k127_7052236_4 PFAM ABC transporter related K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 476.0
HKD1_k127_7052236_5 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000247 194.0
HKD1_k127_7052236_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000002068 166.0
HKD1_k127_7052236_7 - - - - 0.000000000000000000000000000000000001922 148.0
HKD1_k127_7052236_8 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000006397 132.0
HKD1_k127_7052236_9 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000000007978 130.0
HKD1_k127_7058293_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.737e-214 675.0
HKD1_k127_7058293_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 589.0
HKD1_k127_7058293_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 580.0
HKD1_k127_7058293_3 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 306.0
HKD1_k127_7058293_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000004914 237.0
HKD1_k127_7058293_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000008676 233.0
HKD1_k127_7062404_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 5.526e-313 971.0
HKD1_k127_7062404_1 BT1 family - - - 1.959e-223 704.0
HKD1_k127_7062404_10 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 485.0
HKD1_k127_7062404_11 MltA-interacting protein MipA K07274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 476.0
HKD1_k127_7062404_12 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 456.0
HKD1_k127_7062404_13 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 460.0
HKD1_k127_7062404_14 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 435.0
HKD1_k127_7062404_15 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 435.0
HKD1_k127_7062404_16 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 436.0
HKD1_k127_7062404_17 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 417.0
HKD1_k127_7062404_18 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 403.0
HKD1_k127_7062404_19 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 407.0
HKD1_k127_7062404_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.038e-209 676.0
HKD1_k127_7062404_20 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 392.0
HKD1_k127_7062404_21 abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 365.0
HKD1_k127_7062404_22 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 363.0
HKD1_k127_7062404_23 MASE2 domain K18968 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 342.0
HKD1_k127_7062404_24 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 319.0
HKD1_k127_7062404_25 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 316.0
HKD1_k127_7062404_26 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 308.0
HKD1_k127_7062404_27 Enoyl-CoA hydratase carnithine racemase K01692,K11264 - 4.1.1.41,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 303.0
HKD1_k127_7062404_28 Dioxygenase K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001422 269.0
HKD1_k127_7062404_29 pca operon transcription factor PcaQ K02623 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000181 273.0
HKD1_k127_7062404_3 Aminotransferase class I and II K11358 - 2.6.1.1 7.631e-200 627.0
HKD1_k127_7062404_30 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
HKD1_k127_7062404_31 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
HKD1_k127_7062404_32 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000192 239.0
HKD1_k127_7062404_33 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001144 230.0
HKD1_k127_7062404_34 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000001814 235.0
HKD1_k127_7062404_35 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000004815 231.0
HKD1_k127_7062404_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000005734 221.0
HKD1_k127_7062404_37 - - - - 0.0000000000000000000000000000000000000000000000000000000001357 211.0
HKD1_k127_7062404_38 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000537 168.0
HKD1_k127_7062404_39 MAPEG family - - - 0.0000000000000000000000000000000000000000003533 162.0
HKD1_k127_7062404_4 Belongs to the TPP enzyme family K01576 - 4.1.1.7 8.182e-200 638.0
HKD1_k127_7062404_40 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000001524 167.0
HKD1_k127_7062404_41 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000001257 148.0
HKD1_k127_7062404_42 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000003124 141.0
HKD1_k127_7062404_43 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000003046 143.0
HKD1_k127_7062404_44 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000000000004841 140.0
HKD1_k127_7062404_45 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000004201 130.0
HKD1_k127_7062404_46 - - - - 0.0000000000000000000000009877 108.0
HKD1_k127_7062404_47 - - - - 0.000000000000000000000006865 105.0
HKD1_k127_7062404_48 - - - - 0.00000000000000000000005633 110.0
HKD1_k127_7062404_49 protein conserved in bacteria K09937 - - 0.0000000000000000007296 87.0
HKD1_k127_7062404_5 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 611.0
HKD1_k127_7062404_50 - - - - 0.0000000003181 67.0
HKD1_k127_7062404_52 PFAM 17 kDa surface antigen - - - 0.0004985 49.0
HKD1_k127_7062404_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 589.0
HKD1_k127_7062404_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 575.0
HKD1_k127_7062404_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 566.0
HKD1_k127_7062404_9 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 510.0
HKD1_k127_7082873_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000006524 241.0
HKD1_k127_7082873_1 - - - - 0.000000000007872 72.0
HKD1_k127_7116083_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 524.0
HKD1_k127_7116083_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001966 258.0
HKD1_k127_7116083_2 PFAM biotin lipoate A B protein ligase - - - 0.00000000000000000000000000000000000001375 156.0
HKD1_k127_7116083_3 - - - - 0.0000000000000000000000000000000000001137 145.0
HKD1_k127_7116083_4 radical SAM K01012 - 2.8.1.6 0.00000000000000000000000005679 108.0
HKD1_k127_7125802_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 556.0
HKD1_k127_7125802_1 FIST C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 381.0
HKD1_k127_7125802_2 Protein of unknown function (DUF1173) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 375.0
HKD1_k127_7125802_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000004561 198.0
HKD1_k127_7125802_4 RES - - - 0.00000000000000000000000000000000000000000002077 169.0
HKD1_k127_7125802_5 Phage integrase family K07358 GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000004858 166.0
HKD1_k127_7125802_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000001054 156.0
HKD1_k127_7125802_7 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000000002834 139.0
HKD1_k127_7125802_8 AAA domain - - - 0.0000000000000000000000004531 110.0
HKD1_k127_7125802_9 Chromatin associated protein KTI12 K07028 - - 0.00000000000002297 86.0
HKD1_k127_7130367_0 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 401.0
HKD1_k127_7130367_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 347.0
HKD1_k127_7130367_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000001587 213.0
HKD1_k127_7130367_3 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000001869 189.0
HKD1_k127_7130367_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000007494 74.0
HKD1_k127_7130367_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0008741 42.0
HKD1_k127_7159553_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 576.0
HKD1_k127_7159553_1 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
HKD1_k127_7159553_2 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000371 257.0
HKD1_k127_716469_0 Activates fatty acids by binding to coenzyme A K00666 - - 9.157e-219 692.0
HKD1_k127_716469_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 375.0
HKD1_k127_7171864_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 603.0
HKD1_k127_7171864_1 Protein of unknown function (DUF993) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 524.0
HKD1_k127_7171864_10 Protein of unknown function (DUF2844) - - - 0.000000000000001077 87.0
HKD1_k127_7171864_11 Prokaryotic N-terminal methylation motif - - - 0.000000002466 61.0
HKD1_k127_7171864_2 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 482.0
HKD1_k127_7171864_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 389.0
HKD1_k127_7171864_4 PFAM ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 369.0
HKD1_k127_7171864_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 364.0
HKD1_k127_7171864_6 Protein of unknown function (DUF3443) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 362.0
HKD1_k127_7171864_7 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000005098 230.0
HKD1_k127_7171864_8 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000001421 201.0
HKD1_k127_7171864_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000001627 171.0
HKD1_k127_7172972_0 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 361.0
HKD1_k127_7172972_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001734 271.0
HKD1_k127_7172972_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000001579 202.0
HKD1_k127_7172972_3 Small Multidrug Resistance protein - - - 0.00000000000000000000001876 101.0
HKD1_k127_7177314_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 2.707e-288 906.0
HKD1_k127_7177314_1 AMP-binding enzyme K12508 - 6.2.1.34 7.014e-219 691.0
HKD1_k127_7177314_10 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
HKD1_k127_7177314_11 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000753 251.0
HKD1_k127_7177314_12 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000344 213.0
HKD1_k127_7177314_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000001369 209.0
HKD1_k127_7177314_14 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000001024 190.0
HKD1_k127_7177314_15 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000002768 187.0
HKD1_k127_7177314_16 2Fe-2S iron-sulfur cluster binding domain K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000000000000000000000000000000000000000003195 180.0
HKD1_k127_7177314_17 - - - - 0.000000000000000000000000000000000000000000006833 174.0
HKD1_k127_7177314_18 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000004579 136.0
HKD1_k127_7177314_19 Fe-S assembly protein IscX - - - 0.0000000000000000000000008588 111.0
HKD1_k127_7177314_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.446e-214 676.0
HKD1_k127_7177314_20 Histidine kinase-like ATPase domain - - - 0.00000000000000000000001032 111.0
HKD1_k127_7177314_21 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000008547 98.0
HKD1_k127_7177314_22 Domain of unknown function (DUF4124) - - - 0.0008363 50.0
HKD1_k127_7177314_3 Rhodanese Homology Domain - - - 2.103e-196 635.0
HKD1_k127_7177314_4 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 497.0
HKD1_k127_7177314_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 312.0
HKD1_k127_7177314_6 cysteine dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000936 264.0
HKD1_k127_7177314_7 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
HKD1_k127_7177314_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004159 239.0
HKD1_k127_7177314_9 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000005698 249.0
HKD1_k127_7177707_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1100.0
HKD1_k127_7177707_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.03e-252 792.0
HKD1_k127_7177707_10 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000177 215.0
HKD1_k127_7177707_11 glycine cleavage K02437 - - 0.000000000000000000000000000000000000000000000000000001311 194.0
HKD1_k127_7177707_12 DsrE/DsrF-like family K07092 - - 0.00000000000000000000000000000000000000000000001273 191.0
HKD1_k127_7177707_13 - - - - 0.000000000000000000000000000000000000000001955 176.0
HKD1_k127_7177707_14 Sulfurtransferase TusA K04085 - - 0.000000000000000000000000000000003358 129.0
HKD1_k127_7177707_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 565.0
HKD1_k127_7177707_3 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 547.0
HKD1_k127_7177707_4 SMART Elongator protein 3 MiaB NifB K09711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 470.0
HKD1_k127_7177707_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 467.0
HKD1_k127_7177707_6 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 430.0
HKD1_k127_7177707_7 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 398.0
HKD1_k127_7177707_8 PFAM DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
HKD1_k127_7177707_9 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 338.0
HKD1_k127_7180267_0 AcrB/AcrD/AcrF family K18138 - - 0.0 1426.0
HKD1_k127_7180267_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.34e-240 765.0
HKD1_k127_7180267_10 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 452.0
HKD1_k127_7180267_11 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 445.0
HKD1_k127_7180267_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 422.0
HKD1_k127_7180267_13 Acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 393.0
HKD1_k127_7180267_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 360.0
HKD1_k127_7180267_15 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 358.0
HKD1_k127_7180267_16 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 339.0
HKD1_k127_7180267_17 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 325.0
HKD1_k127_7180267_18 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 326.0
HKD1_k127_7180267_19 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001029 289.0
HKD1_k127_7180267_2 HELICc2 K03722 - 3.6.4.12 9.671e-236 747.0
HKD1_k127_7180267_20 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003918 260.0
HKD1_k127_7180267_21 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004326 241.0
HKD1_k127_7180267_22 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000008963 186.0
HKD1_k127_7180267_23 NlpC/P60 family K13695,K19303 - - 0.00000000000000000000000000000000000000007724 156.0
HKD1_k127_7180267_24 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000001374 145.0
HKD1_k127_7180267_25 17 kDa surface antigen - - - 0.00000000000000000000000000000000005125 143.0
HKD1_k127_7180267_26 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000003573 145.0
HKD1_k127_7180267_27 TIGRFAM TonB family protein K03832 - - 0.000000000000000003476 94.0
HKD1_k127_7180267_28 KTSC domain - - - 0.000000000001703 69.0
HKD1_k127_7180267_3 Single-stranded-DNA-specific exonuclease K07462 - - 1.104e-214 680.0
HKD1_k127_7180267_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.537e-213 671.0
HKD1_k127_7180267_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.752e-209 661.0
HKD1_k127_7180267_6 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 1.641e-204 652.0
HKD1_k127_7180267_7 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 604.0
HKD1_k127_7180267_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 546.0
HKD1_k127_7180267_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 532.0
HKD1_k127_7206126_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.241e-215 693.0
HKD1_k127_7206126_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 511.0
HKD1_k127_7206126_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 476.0
HKD1_k127_7206126_3 Universal stress protein family - - - 0.000000000000000000000000000000000000000001187 162.0
HKD1_k127_7206126_4 Cupin - - - 0.0000000000002507 76.0
HKD1_k127_7211871_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.498e-268 842.0
HKD1_k127_7211871_1 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 450.0
HKD1_k127_7211871_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000013 203.0
HKD1_k127_7211871_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000004789 189.0
HKD1_k127_7211871_4 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000009974 104.0
HKD1_k127_7211871_5 - - - - 0.00000000000000005624 90.0
HKD1_k127_7211871_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.0000000036 62.0
HKD1_k127_7218526_0 Penicillin amidase K01434 - 3.5.1.11 4.078e-273 862.0
HKD1_k127_7218526_1 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 554.0
HKD1_k127_7218526_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005921 240.0
HKD1_k127_7218526_3 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000002472 226.0
HKD1_k127_7218526_4 epimerase - - - 0.0000000000000000000000000000000000000000000004173 175.0
HKD1_k127_7218526_5 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000002438 175.0
HKD1_k127_7218526_6 phosphorelay signal transduction system - - - 0.0000000000000000002777 97.0
HKD1_k127_7237425_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 336.0
HKD1_k127_7237425_1 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
HKD1_k127_7237425_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000009456 221.0
HKD1_k127_7240979_0 Elongator protein 3, MiaB family, Radical SAM - - - 6.277e-240 744.0
HKD1_k127_7240979_2 Dimerisation domain - - - 0.000000000000000000000005823 117.0
HKD1_k127_7240979_3 EVE domain - - - 0.000000000000000000002938 94.0
HKD1_k127_7242096_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1291.0
HKD1_k127_7242096_1 Repeat of Unknown Function (DUF347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 346.0
HKD1_k127_7242096_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 305.0
HKD1_k127_7242096_3 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002598 250.0
HKD1_k127_7242096_4 dehydratase K18290 - 4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000001355 218.0
HKD1_k127_7258677_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 2.003e-226 723.0
HKD1_k127_7258677_1 PFAM extracellular solute-binding protein family 1 K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 610.0
HKD1_k127_7258677_10 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 430.0
HKD1_k127_7258677_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 395.0
HKD1_k127_7258677_12 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 360.0
HKD1_k127_7258677_13 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000017 266.0
HKD1_k127_7258677_14 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000009187 258.0
HKD1_k127_7258677_15 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.000000000000000000000000000000000000000000000000000000000002364 220.0
HKD1_k127_7258677_16 General secretion pathway protein K02459,K02672,K02680 - - 0.00000000000000000000000000000000000000000000004855 185.0
HKD1_k127_7258677_17 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000005726 169.0
HKD1_k127_7258677_18 BirA family transcriptional regulator, biotin operon repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000001562 161.0
HKD1_k127_7258677_19 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000001084 134.0
HKD1_k127_7258677_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 587.0
HKD1_k127_7258677_20 Tfp pilus assembly protein K02655 - - 0.00000000000000000000000000003679 124.0
HKD1_k127_7258677_21 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000268 113.0
HKD1_k127_7258677_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000005108 111.0
HKD1_k127_7258677_23 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000009957 103.0
HKD1_k127_7258677_24 Pilus assembly protein PilX - - - 0.000000000000000002977 89.0
HKD1_k127_7258677_25 Protein of unknown function (DUF3833) - - - 0.00000000000000000805 83.0
HKD1_k127_7258677_26 - - - - 0.0000009344 50.0
HKD1_k127_7258677_27 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0004889 52.0
HKD1_k127_7258677_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 589.0
HKD1_k127_7258677_4 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 569.0
HKD1_k127_7258677_5 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 548.0
HKD1_k127_7258677_6 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 528.0
HKD1_k127_7258677_7 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 454.0
HKD1_k127_7258677_8 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 419.0
HKD1_k127_7258677_9 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 415.0
HKD1_k127_7263598_0 Belongs to the amidase family K01426 - 3.5.1.4 1.781e-217 684.0
HKD1_k127_7263598_1 ABC transporter transmembrane region K18893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 353.0
HKD1_k127_7263598_2 Domain of unknown function (DUF4345) - - - 0.0001282 46.0
HKD1_k127_7265534_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1634.0
HKD1_k127_7265534_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.587e-231 720.0
HKD1_k127_7265534_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000006643 226.0
HKD1_k127_7265534_11 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000002652 223.0
HKD1_k127_7265534_12 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000002408 173.0
HKD1_k127_7265534_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000004456 171.0
HKD1_k127_7265534_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000002678 156.0
HKD1_k127_7265534_15 pilus organization K07346 - - 0.000000000000000000000000000000000001553 149.0
HKD1_k127_7265534_16 response regulator - - - 0.0000000001735 70.0
HKD1_k127_7265534_2 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 509.0
HKD1_k127_7265534_20 Spore Coat Protein U domain - - - 0.00004961 52.0
HKD1_k127_7265534_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 383.0
HKD1_k127_7265534_4 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 396.0
HKD1_k127_7265534_5 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 344.0
HKD1_k127_7265534_6 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 313.0
HKD1_k127_7265534_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
HKD1_k127_7265534_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001941 276.0
HKD1_k127_7265534_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001086 241.0
HKD1_k127_7279817_0 Glycogen debranching enzyme - - - 9.631e-314 969.0
HKD1_k127_7279817_1 ErfK YbiS YcfS YnhG family protein K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 449.0
HKD1_k127_7279817_2 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 312.0
HKD1_k127_7279817_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003913 248.0
HKD1_k127_7279817_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001799 208.0
HKD1_k127_7279817_5 HD domain K07814,K13815 - - 0.00000000000000000000000000000000000000001206 160.0
HKD1_k127_7279817_6 - - - - 0.00000000000000000000844 98.0
HKD1_k127_7279817_7 - - - - 0.000001546 54.0
HKD1_k127_7286926_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 5.037e-209 662.0
HKD1_k127_7286926_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 546.0
HKD1_k127_7286926_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 442.0
HKD1_k127_7286926_3 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000491 277.0
HKD1_k127_7286926_4 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000009311 117.0
HKD1_k127_7286926_5 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000001089 115.0
HKD1_k127_7292634_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.571e-222 706.0
HKD1_k127_7292634_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.221e-197 626.0
HKD1_k127_7292634_10 coa-binding K06929 - - 0.0000000000000000000000000000000000000000000001178 173.0
HKD1_k127_7292634_11 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000004662 131.0
HKD1_k127_7292634_12 Transmembrane anti-sigma factor - - - 0.000000000007118 67.0
HKD1_k127_7292634_2 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 464.0
HKD1_k127_7292634_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 457.0
HKD1_k127_7292634_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 374.0
HKD1_k127_7292634_5 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 373.0
HKD1_k127_7292634_6 acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 287.0
HKD1_k127_7292634_7 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000363 235.0
HKD1_k127_7292634_8 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000004471 233.0
HKD1_k127_7292634_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000001496 199.0
HKD1_k127_7302932_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 7.803e-255 809.0
HKD1_k127_7302932_1 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 356.0
HKD1_k127_7302932_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 327.0
HKD1_k127_7302932_3 Phage plasmid primase P4 family K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 318.0
HKD1_k127_7302932_4 GYD domain - - - 0.000000000000000000000000000000000001125 140.0
HKD1_k127_7302932_5 - - - - 0.00000000000000001761 89.0
HKD1_k127_7302932_6 Protein of unknown function (DUF2384) - - - 0.00000002362 63.0
HKD1_k127_7302932_7 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.0001219 51.0
HKD1_k127_7302932_8 Protein of unknown function (DUF2934) - - - 0.0002429 45.0
HKD1_k127_7309949_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 1.268e-223 711.0
HKD1_k127_7309949_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 530.0
HKD1_k127_7309949_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005393 282.0
HKD1_k127_7309949_3 - - - - 0.00000000000000000000000000000000000000000000002305 173.0
HKD1_k127_7309949_4 HD domain - - - 0.0000000000000000000000000000000000004646 142.0
HKD1_k127_7309949_5 nucleic-acid-binding protein contains PIN domain - - - 0.0000000000000000000000000000004474 128.0
HKD1_k127_7338537_0 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009419 282.0
HKD1_k127_7338537_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000002111 219.0
HKD1_k127_7338537_2 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000003027 212.0
HKD1_k127_7338537_3 Protein of unknown function (DUF504) - - - 0.000000000000000000002542 106.0
HKD1_k127_7369198_0 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 419.0
HKD1_k127_7369198_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 323.0
HKD1_k127_7369198_2 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.0000000000001476 73.0
HKD1_k127_7369198_3 - - - - 0.00000000001201 74.0
HKD1_k127_73694_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 9.737e-315 972.0
HKD1_k127_73694_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 6.194e-312 966.0
HKD1_k127_73694_10 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 304.0
HKD1_k127_73694_11 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 312.0
HKD1_k127_73694_12 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006143 248.0
HKD1_k127_73694_13 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000001793 243.0
HKD1_k127_73694_14 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000002707 241.0
HKD1_k127_73694_15 Acetolactate synthase small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000001714 256.0
HKD1_k127_73694_16 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000004495 227.0
HKD1_k127_73694_17 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000008805 210.0
HKD1_k127_73694_18 Multidrug Resistance protein K11741 - - 0.0000000000000000000000000000000000000000000000001411 178.0
HKD1_k127_73694_19 Translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000005581 154.0
HKD1_k127_73694_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.607e-246 769.0
HKD1_k127_73694_20 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000003581 154.0
HKD1_k127_73694_21 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000409 155.0
HKD1_k127_73694_22 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000001467 142.0
HKD1_k127_73694_23 RDD family - - - 0.00000000000000000000000000006018 127.0
HKD1_k127_73694_24 Protein of unknown function (DUF3106) - - - 0.0000000000000000003309 98.0
HKD1_k127_73694_25 - - - - 0.000007689 53.0
HKD1_k127_73694_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 590.0
HKD1_k127_73694_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 571.0
HKD1_k127_73694_5 Permease YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 374.0
HKD1_k127_73694_6 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 389.0
HKD1_k127_73694_7 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 366.0
HKD1_k127_73694_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 340.0
HKD1_k127_73694_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 312.0
HKD1_k127_7371743_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969,K13778 - 6.4.1.4,6.4.1.5 2.028e-233 733.0
HKD1_k127_7371743_1 acyl-CoA dehydrogenase K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 627.0
HKD1_k127_7371743_2 Biotin carboxylase C-terminal domain K13777 - 6.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 572.0
HKD1_k127_7371743_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005507 299.0
HKD1_k127_7371743_4 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000002154 231.0
HKD1_k127_7371743_5 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000008722 180.0
HKD1_k127_7387668_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 422.0
HKD1_k127_7395078_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1349.0
HKD1_k127_7395078_1 pilus assembly protein tip-associated adhesin K02674 - - 1.15e-274 897.0
HKD1_k127_7395078_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 465.0
HKD1_k127_7395078_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000006609 174.0
HKD1_k127_7395078_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000001636 85.0
HKD1_k127_7412018_0 Luciferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 580.0
HKD1_k127_7412018_1 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 513.0
HKD1_k127_7412018_2 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 415.0
HKD1_k127_7412018_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 357.0
HKD1_k127_7412018_4 MAPEG family - - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
HKD1_k127_7412018_5 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
HKD1_k127_7412018_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000026 115.0
HKD1_k127_7412018_7 transglycosylase associated protein - - - 0.00000000000000001983 82.0
HKD1_k127_7430588_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1309.0
HKD1_k127_7430588_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.668e-295 913.0
HKD1_k127_7430588_10 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 497.0
HKD1_k127_7430588_11 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 460.0
HKD1_k127_7430588_12 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 454.0
HKD1_k127_7430588_13 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 432.0
HKD1_k127_7430588_14 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 405.0
HKD1_k127_7430588_15 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 383.0
HKD1_k127_7430588_16 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 321.0
HKD1_k127_7430588_17 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000002112 232.0
HKD1_k127_7430588_18 Cytidylate kinase - - - 0.000000000000000000000000000000000000000000000000000000000009172 231.0
HKD1_k127_7430588_19 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000004082 169.0
HKD1_k127_7430588_2 UDP binding domain K00012 - 1.1.1.22 3.274e-197 628.0
HKD1_k127_7430588_20 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000001013 125.0
HKD1_k127_7430588_21 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000000002673 85.0
HKD1_k127_7430588_3 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 612.0
HKD1_k127_7430588_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 567.0
HKD1_k127_7430588_5 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 533.0
HKD1_k127_7430588_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 541.0
HKD1_k127_7430588_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 542.0
HKD1_k127_7430588_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 514.0
HKD1_k127_7430588_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 504.0
HKD1_k127_7436729_0 FAD binding domain - - - 7.146e-194 621.0
HKD1_k127_7436729_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 540.0
HKD1_k127_7436729_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 331.0
HKD1_k127_7465001_0 cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 407.0
HKD1_k127_7465001_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000642 199.0
HKD1_k127_7465001_2 Hsp20/alpha crystallin family K13993 - - 0.0000000000000004847 85.0
HKD1_k127_7488776_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1315.0
HKD1_k127_7488776_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 3.209e-316 985.0
HKD1_k127_7488776_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 321.0
HKD1_k127_7488776_11 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 293.0
HKD1_k127_7488776_12 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004138 263.0
HKD1_k127_7488776_13 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003884 244.0
HKD1_k127_7488776_14 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002929 242.0
HKD1_k127_7488776_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000001311 199.0
HKD1_k127_7488776_16 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000001838 193.0
HKD1_k127_7488776_17 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000001602 167.0
HKD1_k127_7488776_18 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000000000005834 158.0
HKD1_k127_7488776_19 Belongs to the frataxin K06202 - - 0.0000000000000000000000000000000000131 138.0
HKD1_k127_7488776_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 615.0
HKD1_k127_7488776_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 518.0
HKD1_k127_7488776_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 510.0
HKD1_k127_7488776_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 501.0
HKD1_k127_7488776_6 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 481.0
HKD1_k127_7488776_7 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 420.0
HKD1_k127_7488776_8 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 405.0
HKD1_k127_7488776_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 325.0
HKD1_k127_7555055_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1070.0
HKD1_k127_7555055_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 563.0
HKD1_k127_7555055_2 Dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 285.0
HKD1_k127_7555055_3 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000004126 237.0
HKD1_k127_7555055_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000001641 192.0
HKD1_k127_7555055_5 3-Hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000882 162.0
HKD1_k127_7555055_6 Modulates RecA activity K03565 - - 0.00000000000000000000000000008013 121.0
HKD1_k127_7572665_0 Amidohydrolase family - - - 1.254e-259 809.0
HKD1_k127_7572665_1 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 586.0
HKD1_k127_7572665_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 435.0
HKD1_k127_7572665_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000004594 248.0
HKD1_k127_7572665_4 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000004836 230.0
HKD1_k127_7572665_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000003233 150.0
HKD1_k127_7572665_6 - - - - 0.0000000001638 68.0
HKD1_k127_7642651_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 591.0
HKD1_k127_7642651_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 450.0
HKD1_k127_7642651_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001032 299.0
HKD1_k127_7642651_3 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008177 281.0
HKD1_k127_7642651_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000004749 204.0
HKD1_k127_7642651_5 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000006649 193.0
HKD1_k127_7642651_6 AIR synthase related protein, N-terminal domain K00946 - 2.7.4.16 0.00000000000000000000000000000000001328 140.0
HKD1_k127_7642651_7 helix_turn_helix, Lux Regulon - - - 0.000000000000402 69.0
HKD1_k127_7642651_8 Sel1 domain protein repeat-containing protein K07126 - - 0.00008184 52.0
HKD1_k127_7642651_9 Sel1 domain protein repeat-containing protein K07126 - - 0.0008503 49.0
HKD1_k127_7651084_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 565.0
HKD1_k127_7651084_1 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 472.0
HKD1_k127_7651084_10 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002345 291.0
HKD1_k127_7651084_11 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000005304 265.0
HKD1_k127_7651084_12 DoxX K15977 - - 0.00000000000000000000000000000000004996 139.0
HKD1_k127_7651084_13 membrane - - - 0.00000000000000000000000000000002683 129.0
HKD1_k127_7651084_14 nitric oxide dioxygenase activity - - - 0.00000000000000000001529 96.0
HKD1_k127_7651084_15 - - - - 0.000000000000001313 83.0
HKD1_k127_7651084_16 Thioesterase superfamily - - - 0.00004249 47.0
HKD1_k127_7651084_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 466.0
HKD1_k127_7651084_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 440.0
HKD1_k127_7651084_4 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 414.0
HKD1_k127_7651084_5 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 413.0
HKD1_k127_7651084_6 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 389.0
HKD1_k127_7651084_7 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 283.0
HKD1_k127_7651084_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001085 303.0
HKD1_k127_7651084_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001301 283.0
HKD1_k127_765561_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1379.0
HKD1_k127_765561_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 400.0
HKD1_k127_765561_2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.000000000000000000000000000000000000000000000007498 180.0
HKD1_k127_765561_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000001005 113.0
HKD1_k127_765561_4 (Hpt) domain - - - 0.00000000000000000006485 93.0
HKD1_k127_765561_5 SnoaL-like domain - - - 0.00000000000005213 74.0
HKD1_k127_7667635_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.908e-231 734.0
HKD1_k127_7667635_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 4.739e-201 642.0
HKD1_k127_7667635_10 SPW repeat - - - 0.000000000000000000001226 97.0
HKD1_k127_7667635_2 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 357.0
HKD1_k127_7667635_3 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000004409 267.0
HKD1_k127_7667635_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000001188 186.0
HKD1_k127_7667635_5 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000001128 153.0
HKD1_k127_7667635_6 Nuclease-related domain - - - 0.00000000000000000000000000000000000007102 153.0
HKD1_k127_7667635_7 Cytochrome c - - - 0.0000000000000000000000000000000003968 137.0
HKD1_k127_7667635_8 acetyltransferase - - - 0.00000000000000000000000000002403 128.0
HKD1_k127_7667635_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000001166 113.0
HKD1_k127_7681377_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1456.0
HKD1_k127_7681377_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 554.0
HKD1_k127_7681377_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 360.0
HKD1_k127_7681377_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 321.0
HKD1_k127_7681377_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 299.0
HKD1_k127_7681377_5 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000003489 182.0
HKD1_k127_7681377_6 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000271 124.0
HKD1_k127_7681377_7 Sulfurtransferase - - - 0.0000000000000000000000008116 105.0
HKD1_k127_7681377_8 Metal-sensitive transcriptional repressor - - - 0.000000000000000001787 87.0
HKD1_k127_7681377_9 Prokaryotic N-terminal methylation motif - - - 0.000000000000000008861 84.0
HKD1_k127_7688664_0 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 351.0
HKD1_k127_7688664_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000002443 221.0
HKD1_k127_7688664_2 Transposase - - - 0.0001659 47.0
HKD1_k127_7771552_0 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 561.0
HKD1_k127_7771552_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 449.0
HKD1_k127_7771552_2 Cholesterol oxidase K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 379.0
HKD1_k127_7771552_3 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005888 267.0
HKD1_k127_7771552_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000001115 187.0
HKD1_k127_7771552_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000007873 173.0
HKD1_k127_7771552_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000004018 158.0
HKD1_k127_7771552_7 COG3773 Cell wall hydrolyses involved in spore germination - - - 0.00000000000000000000001029 108.0
HKD1_k127_7781432_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 590.0
HKD1_k127_7781432_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 467.0
HKD1_k127_7781432_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 311.0
HKD1_k127_7781432_11 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000005732 213.0
HKD1_k127_7781432_12 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000004596 216.0
HKD1_k127_7781432_13 Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only K02503 - - 0.0000000000000000000000000000000000000000001345 168.0
HKD1_k127_7781432_14 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.0000000000000000000000000000000004544 140.0
HKD1_k127_7781432_15 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000001764 125.0
HKD1_k127_7781432_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000005313 122.0
HKD1_k127_7781432_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000001641 109.0
HKD1_k127_7781432_18 (ABC) transporter K11004,K13409 - - 0.00000000004932 69.0
HKD1_k127_7781432_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 392.0
HKD1_k127_7781432_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 389.0
HKD1_k127_7781432_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009022 399.0
HKD1_k127_7781432_5 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 359.0
HKD1_k127_7781432_6 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 336.0
HKD1_k127_7781432_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 337.0
HKD1_k127_7781432_8 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 331.0
HKD1_k127_7781432_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 321.0
HKD1_k127_78387_0 Bacterial protein of unknown function (DUF885) - - - 1.271e-196 631.0
HKD1_k127_78387_1 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000002156 155.0
HKD1_k127_7854321_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 479.0
HKD1_k127_7854321_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 436.0
HKD1_k127_7854321_2 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 330.0
HKD1_k127_7854321_4 Cupredoxin-like domain - - - 0.00000000000007407 75.0
HKD1_k127_7884952_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 6.349e-309 964.0
HKD1_k127_7884952_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.42e-283 884.0
HKD1_k127_7884952_10 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 344.0
HKD1_k127_7884952_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 320.0
HKD1_k127_7884952_12 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 290.0
HKD1_k127_7884952_13 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002872 275.0
HKD1_k127_7884952_14 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001092 271.0
HKD1_k127_7884952_15 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003564 259.0
HKD1_k127_7884952_16 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
HKD1_k127_7884952_17 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
HKD1_k127_7884952_18 glycosyl transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004749 243.0
HKD1_k127_7884952_19 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000361 215.0
HKD1_k127_7884952_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 1.23e-204 645.0
HKD1_k127_7884952_20 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000002292 204.0
HKD1_k127_7884952_21 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000001404 206.0
HKD1_k127_7884952_22 PFAM transport-associated - - - 0.00000000000000000000000000000000000000000000000000008247 201.0
HKD1_k127_7884952_23 Small MutS-related domain - - - 0.00000000000000000000000000000000000000000000000001102 189.0
HKD1_k127_7884952_24 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000001506 135.0
HKD1_k127_7884952_25 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000391 128.0
HKD1_k127_7884952_26 - - - - 0.000000000000000000000000162 112.0
HKD1_k127_7884952_27 diguanylate cyclase - - - 0.0000000009086 66.0
HKD1_k127_7884952_3 PFAM ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 577.0
HKD1_k127_7884952_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 551.0
HKD1_k127_7884952_5 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 544.0
HKD1_k127_7884952_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 507.0
HKD1_k127_7884952_7 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 507.0
HKD1_k127_7884952_8 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 494.0
HKD1_k127_7884952_9 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 445.0
HKD1_k127_7927532_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.686e-230 717.0
HKD1_k127_7927532_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 542.0
HKD1_k127_7927532_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000006284 190.0
HKD1_k127_7927532_11 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000007074 197.0
HKD1_k127_7927532_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000001786 191.0
HKD1_k127_7927532_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000002369 145.0
HKD1_k127_7927532_14 Ribosomal protein L30 K02907 - - 0.0000000000000000634 87.0
HKD1_k127_7927532_15 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0000000000000128 73.0
HKD1_k127_7927532_16 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003032 71.0
HKD1_k127_7927532_2 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 557.0
HKD1_k127_7927532_3 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 471.0
HKD1_k127_7927532_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 348.0
HKD1_k127_7927532_5 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 299.0
HKD1_k127_7927532_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003769 264.0
HKD1_k127_7927532_7 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 256.0
HKD1_k127_7927532_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000005462 233.0
HKD1_k127_7927532_9 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000001654 208.0
HKD1_k127_7931568_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 339.0
HKD1_k127_7931568_1 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000395 231.0
HKD1_k127_7931568_2 - - - - 0.000000000000000002352 97.0
HKD1_k127_7958438_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.385e-199 631.0
HKD1_k127_7958438_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.209e-195 612.0
HKD1_k127_7958438_10 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000003356 233.0
HKD1_k127_7958438_11 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000006276 197.0
HKD1_k127_7958438_12 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000376 169.0
HKD1_k127_7958438_13 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000001479 158.0
HKD1_k127_7958438_14 Universal stress protein - - - 0.0000000000000000000000000000000000001721 146.0
HKD1_k127_7958438_15 FixH K09926 - - 0.00000000000000000000000000000000001316 155.0
HKD1_k127_7958438_16 - - - - 0.000000000000000000001521 97.0
HKD1_k127_7958438_17 Pfam Response regulator receiver - - - 0.000000000000000002628 90.0
HKD1_k127_7958438_18 Cytochrome c - - - 0.000000001226 64.0
HKD1_k127_7958438_19 PFAM Cbb3-type cytochrome oxidase component K00407 - - 0.00000003771 58.0
HKD1_k127_7958438_2 cytochrome C oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 602.0
HKD1_k127_7958438_3 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 543.0
HKD1_k127_7958438_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 395.0
HKD1_k127_7958438_5 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 329.0
HKD1_k127_7958438_6 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 319.0
HKD1_k127_7958438_7 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 315.0
HKD1_k127_7958438_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 306.0
HKD1_k127_7958438_9 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000164 265.0
HKD1_k127_7970916_0 Adenylate kinase, active site lid K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000001014 249.0
HKD1_k127_7970916_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000001916 181.0
HKD1_k127_7970916_2 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.000005756 55.0
HKD1_k127_84336_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 385.0
HKD1_k127_84336_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 383.0
HKD1_k127_84336_2 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001045 274.0
HKD1_k127_84336_3 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000001498 144.0
HKD1_k127_84336_4 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.000000000000000000000000001968 112.0
HKD1_k127_849606_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 609.0
HKD1_k127_849606_1 - - - - 0.0000000000000000000000000004249 130.0
HKD1_k127_86874_0 AcrB/AcrD/AcrF family - - - 0.0 1304.0
HKD1_k127_86874_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.43e-321 1011.0
HKD1_k127_86874_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 589.0
HKD1_k127_86874_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 435.0
HKD1_k127_86874_4 Outer membrane efflux protein K19123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 381.0
HKD1_k127_86874_5 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 308.0
HKD1_k127_86874_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003946 285.0
HKD1_k127_86874_7 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000001581 235.0
HKD1_k127_90072_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 2.561e-270 849.0
HKD1_k127_90072_1 HlyD family secretion protein K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 430.0
HKD1_k127_90072_2 Glutaredoxin-family domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 415.0
HKD1_k127_90072_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 415.0
HKD1_k127_90072_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 318.0
HKD1_k127_90072_5 MazG-like family - - - 0.0000000000000000000000000000009527 123.0
HKD1_k127_90072_6 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 0.0000001917 56.0
HKD1_k127_918961_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001535 276.0
HKD1_k127_918961_1 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000002516 119.0
HKD1_k127_918961_2 - - - - 0.000000000000000101 93.0