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Overview

ID MAG01755
Name HKD1_bin.75
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order ATCC43930
Family CGMCC-115725
Genus DASZHJ01
Species
Assembly information
Completeness (%) 77.91
Contamination (%) 0.61
GC content (%) 68.0
N50 (bp) 12,493
Genome size (bp) 3,724,322

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3605

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1011566_0 GTP-binding protein TypA K06207 - - 5e-324 1000.0
HKD1_k127_1011566_1 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 436.0
HKD1_k127_1011566_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 306.0
HKD1_k127_1011566_3 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005226 254.0
HKD1_k127_1011566_4 Domain of unknown function (DUF4166) - - - 0.000000000000000000000005364 104.0
HKD1_k127_1011566_5 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000000000000000003956 99.0
HKD1_k127_1011566_6 Domain of unknown function (DUF4166) - - - 0.000000000000001189 81.0
HKD1_k127_1011566_8 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000001485 75.0
HKD1_k127_1013533_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 607.0
HKD1_k127_1013533_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 574.0
HKD1_k127_1013533_10 NUDIX domain K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000009064 219.0
HKD1_k127_1013533_11 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000004874 198.0
HKD1_k127_1013533_12 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000000000000005467 178.0
HKD1_k127_1013533_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000004406 120.0
HKD1_k127_1013533_2 ABC transporter substrate-binding protein K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 429.0
HKD1_k127_1013533_3 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 395.0
HKD1_k127_1013533_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 358.0
HKD1_k127_1013533_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 357.0
HKD1_k127_1013533_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
HKD1_k127_1013533_7 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 314.0
HKD1_k127_1013533_8 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005366 256.0
HKD1_k127_1013533_9 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000002898 232.0
HKD1_k127_1017112_0 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 325.0
HKD1_k127_1017112_1 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008411 248.0
HKD1_k127_1035532_0 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 455.0
HKD1_k127_1035532_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 460.0
HKD1_k127_1035532_10 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000007931 147.0
HKD1_k127_1035532_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000002356 132.0
HKD1_k127_1035532_2 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
HKD1_k127_1035532_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 329.0
HKD1_k127_1035532_5 AraC-binding-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 318.0
HKD1_k127_1035532_6 Uracil-DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006391 279.0
HKD1_k127_1035532_7 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
HKD1_k127_1035532_8 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001118 263.0
HKD1_k127_1035532_9 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000001147 195.0
HKD1_k127_1037146_0 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 591.0
HKD1_k127_1037146_1 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000003586 145.0
HKD1_k127_1037146_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000001449 83.0
HKD1_k127_1037755_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 571.0
HKD1_k127_1037755_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 562.0
HKD1_k127_1037755_2 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002925 244.0
HKD1_k127_1037755_3 transport - - - 0.000000000000000000000000000000000000000000001974 171.0
HKD1_k127_1037755_4 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000002181 55.0
HKD1_k127_1061638_0 Amidase - - - 1.333e-254 790.0
HKD1_k127_1061638_1 Luciferase-like monooxygenase - - - 4.183e-242 753.0
HKD1_k127_1061638_10 Isocitrate/isopropylmalate dehydrogenase K00030,K00031,K00052 - 1.1.1.41,1.1.1.42,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 358.0
HKD1_k127_1061638_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 339.0
HKD1_k127_1061638_12 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 315.0
HKD1_k127_1061638_13 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 303.0
HKD1_k127_1061638_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 296.0
HKD1_k127_1061638_15 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000001939 253.0
HKD1_k127_1061638_16 Cytochrome c - - - 0.000000000000000005284 94.0
HKD1_k127_1061638_17 Transcriptional regulator - - - 0.0000000006331 68.0
HKD1_k127_1061638_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 603.0
HKD1_k127_1061638_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 611.0
HKD1_k127_1061638_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 480.0
HKD1_k127_1061638_5 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 467.0
HKD1_k127_1061638_6 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 397.0
HKD1_k127_1061638_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 392.0
HKD1_k127_1061638_8 Rieske 2Fe-2S domain protein K14748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 389.0
HKD1_k127_1061638_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 382.0
HKD1_k127_1092915_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1002.0
HKD1_k127_1092915_1 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 577.0
HKD1_k127_1092915_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 554.0
HKD1_k127_1092915_3 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 431.0
HKD1_k127_1092915_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 368.0
HKD1_k127_1092915_5 sugar phosphatases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 342.0
HKD1_k127_1092915_6 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000000000000000000000002367 169.0
HKD1_k127_1092915_7 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000002351 138.0
HKD1_k127_1096891_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.894e-211 661.0
HKD1_k127_1096891_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 586.0
HKD1_k127_1096891_2 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 360.0
HKD1_k127_1096891_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 316.0
HKD1_k127_1096891_4 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000001521 211.0
HKD1_k127_1096891_5 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000008473 204.0
HKD1_k127_1096891_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000003909 189.0
HKD1_k127_1098587_0 DNA polymerase K02337 - 2.7.7.7 0.0 1438.0
HKD1_k127_1098587_1 AMP-binding enzyme C-terminal domain - - - 2.687e-245 767.0
HKD1_k127_1098587_10 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
HKD1_k127_1098587_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 361.0
HKD1_k127_1098587_12 Coenzyme A transferase K01034 - 2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 338.0
HKD1_k127_1098587_13 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 316.0
HKD1_k127_1098587_14 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 305.0
HKD1_k127_1098587_15 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002867 280.0
HKD1_k127_1098587_16 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000005852 228.0
HKD1_k127_1098587_17 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000008119 162.0
HKD1_k127_1098587_18 cytochrome - - - 0.0000000000000000000001303 103.0
HKD1_k127_1098587_19 Protein of unknown function (DUF1467) - - - 0.00000000000000000003383 91.0
HKD1_k127_1098587_2 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 6.497e-232 746.0
HKD1_k127_1098587_20 Coenzyme A transferase - - - 0.000000000007195 74.0
HKD1_k127_1098587_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 3.106e-226 709.0
HKD1_k127_1098587_4 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 610.0
HKD1_k127_1098587_5 de-polymerase K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 602.0
HKD1_k127_1098587_6 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 559.0
HKD1_k127_1098587_7 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 521.0
HKD1_k127_1098587_8 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 445.0
HKD1_k127_1098587_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 385.0
HKD1_k127_1102085_0 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 530.0
HKD1_k127_1102085_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 355.0
HKD1_k127_1102085_2 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 307.0
HKD1_k127_1102085_3 KDPG and KHG aldolase K01631 - 4.1.2.21 0.000000000000000000000000000000000000000000000000000000000001075 238.0
HKD1_k127_1102085_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000002099 134.0
HKD1_k127_1102085_5 Cytochrome c - - - 0.0004317 43.0
HKD1_k127_1129601_0 Domain of unknown function (DUF4175) - - - 1.195e-262 832.0
HKD1_k127_1129601_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 386.0
HKD1_k127_1129601_2 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000000000000436 167.0
HKD1_k127_1129601_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000376 169.0
HKD1_k127_1129601_4 Spore Coat - - - 0.0000000000000000000776 96.0
HKD1_k127_1143533_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 4.647e-275 856.0
HKD1_k127_1143533_1 Gentisate 1,2-dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 514.0
HKD1_k127_1143533_10 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 381.0
HKD1_k127_1143533_11 Phytoene synthase K21678 - 2.5.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 351.0
HKD1_k127_1143533_12 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007531 271.0
HKD1_k127_1143533_13 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000000003121 236.0
HKD1_k127_1143533_14 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000002142 205.0
HKD1_k127_1143533_15 Ring hydroxylating beta subunit K16320,K18243 - 1.14.12.1,1.14.13.172 0.0000000000000000000000000000000000000000002983 178.0
HKD1_k127_1143533_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000007531 150.0
HKD1_k127_1143533_2 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 522.0
HKD1_k127_1143533_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 495.0
HKD1_k127_1143533_4 dioxygenase alpha subunit K16319,K18242 - 1.14.12.1,1.14.13.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 485.0
HKD1_k127_1143533_5 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 440.0
HKD1_k127_1143533_6 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 447.0
HKD1_k127_1143533_7 4-hydroxy-tetrahydrodipicolinate synthase K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 399.0
HKD1_k127_1143533_8 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 396.0
HKD1_k127_1143533_9 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 369.0
HKD1_k127_1189903_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.075e-268 835.0
HKD1_k127_1189903_1 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 388.0
HKD1_k127_1189903_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 321.0
HKD1_k127_1189903_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000001068 253.0
HKD1_k127_1200374_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1394.0
HKD1_k127_1200374_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.284e-300 934.0
HKD1_k127_1200374_10 transglycosylase - - - 0.000004111 50.0
HKD1_k127_1200374_2 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 3.22e-247 773.0
HKD1_k127_1200374_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 555.0
HKD1_k127_1200374_4 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 439.0
HKD1_k127_1200374_5 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 387.0
HKD1_k127_1200374_6 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 276.0
HKD1_k127_1200374_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006955 252.0
HKD1_k127_1200374_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.0000000000000000000000000000000000000000000000000000007887 212.0
HKD1_k127_1200374_9 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000000000000000000353 135.0
HKD1_k127_1200868_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1064.0
HKD1_k127_1200868_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.752e-196 617.0
HKD1_k127_1200868_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 597.0
HKD1_k127_1200868_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 542.0
HKD1_k127_1200868_4 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 538.0
HKD1_k127_1200868_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 364.0
HKD1_k127_1200868_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008522 307.0
HKD1_k127_1200868_7 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001351 259.0
HKD1_k127_1200868_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000211 92.0
HKD1_k127_1200868_9 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000002254 57.0
HKD1_k127_1203845_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 0.0 1077.0
HKD1_k127_1203845_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.497e-321 991.0
HKD1_k127_1203845_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 429.0
HKD1_k127_1203845_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 417.0
HKD1_k127_1203845_12 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 404.0
HKD1_k127_1203845_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 392.0
HKD1_k127_1203845_14 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 395.0
HKD1_k127_1203845_15 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 - 2.7.4.23 0.00000000000000000000000000000000000000000000001035 181.0
HKD1_k127_1203845_16 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000001673 145.0
HKD1_k127_1203845_17 transcriptional regulator - - - 0.000000000000000002677 95.0
HKD1_k127_1203845_18 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000003999 70.0
HKD1_k127_1203845_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.781e-233 731.0
HKD1_k127_1203845_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.566e-205 651.0
HKD1_k127_1203845_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 624.0
HKD1_k127_1203845_5 COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family K18459 - 3.5.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 558.0
HKD1_k127_1203845_6 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 540.0
HKD1_k127_1203845_7 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 522.0
HKD1_k127_1203845_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 461.0
HKD1_k127_1203845_9 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 459.0
HKD1_k127_121202_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.745e-244 780.0
HKD1_k127_121202_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 576.0
HKD1_k127_121202_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 542.0
HKD1_k127_121202_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 432.0
HKD1_k127_121202_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 429.0
HKD1_k127_121202_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000002731 177.0
HKD1_k127_1230188_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 8.264e-244 770.0
HKD1_k127_1230188_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 6.802e-239 750.0
HKD1_k127_1230188_10 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 411.0
HKD1_k127_1230188_11 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 377.0
HKD1_k127_1230188_12 Branched-chain amino acid ATP-binding cassette transporter K01995 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 377.0
HKD1_k127_1230188_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 358.0
HKD1_k127_1230188_14 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 350.0
HKD1_k127_1230188_15 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 305.0
HKD1_k127_1230188_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002789 268.0
HKD1_k127_1230188_17 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000001465 171.0
HKD1_k127_1230188_18 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000003716 151.0
HKD1_k127_1230188_2 ATP-dependent helicase K03579 - 3.6.4.13 1.337e-233 736.0
HKD1_k127_1230188_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 5.612e-223 700.0
HKD1_k127_1230188_4 CoA-transferase family III - - - 1.035e-195 621.0
HKD1_k127_1230188_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 584.0
HKD1_k127_1230188_6 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 524.0
HKD1_k127_1230188_7 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 471.0
HKD1_k127_1230188_8 Amidohydrolase family K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 431.0
HKD1_k127_1230188_9 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 424.0
HKD1_k127_1234303_0 SMP-30/Gluconolaconase/LRE-like region K01053,K02352 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 458.0
HKD1_k127_1234303_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 419.0
HKD1_k127_1234303_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 410.0
HKD1_k127_1234303_3 Pfam ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 368.0
HKD1_k127_1234303_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 345.0
HKD1_k127_1234303_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000001068 215.0
HKD1_k127_1234303_6 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000008767 202.0
HKD1_k127_1241770_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1381.0
HKD1_k127_1241770_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 388.0
HKD1_k127_1241770_2 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 368.0
HKD1_k127_1241770_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 301.0
HKD1_k127_1241770_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 280.0
HKD1_k127_1241770_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000003735 192.0
HKD1_k127_1241770_6 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000002199 170.0
HKD1_k127_1241770_7 Domain of unknown function (DUF4167) - - - 0.00000000000000000000000000000001333 132.0
HKD1_k127_1249432_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 4.983e-265 833.0
HKD1_k127_1249432_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 593.0
HKD1_k127_1249432_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 403.0
HKD1_k127_1249432_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 331.0
HKD1_k127_1249432_4 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 288.0
HKD1_k127_1249432_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000005698 249.0
HKD1_k127_1249432_6 self proteolysis K03466,K06196,K12132 - 2.7.11.1 0.000000000000000000000000000000000000001017 154.0
HKD1_k127_1249432_7 Major facilitator superfamily K08369 - - 0.000000000000000000000000000000000000009995 162.0
HKD1_k127_1249432_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000001485 144.0
HKD1_k127_1249432_9 domain, Protein K01227,K07260,K13714,K13731 - 3.2.1.96,3.4.17.14,3.5.1.28 0.000000003285 68.0
HKD1_k127_1249815_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 1.292e-250 785.0
HKD1_k127_1249815_1 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 553.0
HKD1_k127_1249815_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 402.0
HKD1_k127_1249815_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 349.0
HKD1_k127_1249815_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 298.0
HKD1_k127_1249815_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000799 252.0
HKD1_k127_1249815_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001512 254.0
HKD1_k127_1249815_7 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000006504 158.0
HKD1_k127_1249815_8 Glycosyl transferase family 41 - - - 0.00000001928 64.0
HKD1_k127_1254921_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 323.0
HKD1_k127_1254921_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000005163 205.0
HKD1_k127_1254921_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000008232 143.0
HKD1_k127_1269110_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 584.0
HKD1_k127_1269110_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 466.0
HKD1_k127_1269110_2 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000003753 159.0
HKD1_k127_1269110_3 alpha, beta - - - 0.00000000000000000000000000002556 121.0
HKD1_k127_1269110_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000006179 55.0
HKD1_k127_1297861_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 3.557e-199 629.0
HKD1_k127_1297861_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.357e-196 623.0
HKD1_k127_1297861_10 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000001876 183.0
HKD1_k127_1297861_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 503.0
HKD1_k127_1297861_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 348.0
HKD1_k127_1297861_4 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 327.0
HKD1_k127_1297861_5 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 311.0
HKD1_k127_1297861_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002897 267.0
HKD1_k127_1297861_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000007689 205.0
HKD1_k127_1297861_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000113 187.0
HKD1_k127_1297861_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000008102 196.0
HKD1_k127_132010_0 transferase activity, transferring glycosyl groups - - - 1.233e-198 626.0
HKD1_k127_132010_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 456.0
HKD1_k127_132010_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 373.0
HKD1_k127_132010_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 335.0
HKD1_k127_132010_4 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 326.0
HKD1_k127_132010_5 transcriptional regulator K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 266.0
HKD1_k127_132010_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000002051 219.0
HKD1_k127_132010_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000005967 126.0
HKD1_k127_132451_0 Belongs to the CinA family - - - 2.677e-198 629.0
HKD1_k127_132451_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 614.0
HKD1_k127_132451_10 ABC transporter K01996 - - 0.000000000000000000007613 93.0
HKD1_k127_132451_11 - - - - 0.00000000006862 70.0
HKD1_k127_132451_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 493.0
HKD1_k127_132451_3 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 494.0
HKD1_k127_132451_4 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 436.0
HKD1_k127_132451_5 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
HKD1_k127_132451_6 Sir2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 318.0
HKD1_k127_132451_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008303 253.0
HKD1_k127_132451_8 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000001041 209.0
HKD1_k127_132451_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000008284 122.0
HKD1_k127_1347392_0 Beta-lactamase K01286 - 3.4.16.4 8.568e-201 636.0
HKD1_k127_1347392_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 529.0
HKD1_k127_1347392_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000000000000000000003131 205.0
HKD1_k127_1347392_3 GYD domain - - - 0.00000000000000000000003368 116.0
HKD1_k127_1347392_4 Uncharacterized ACR, COG1993 K09137 - - 0.0000002199 52.0
HKD1_k127_1347392_5 Thioesterase-like superfamily K07107 - - 0.00003667 53.0
HKD1_k127_1364912_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.903e-308 955.0
HKD1_k127_1364912_1 secretion system protein K02283 - - 5.092e-202 642.0
HKD1_k127_1364912_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002672 268.0
HKD1_k127_1364912_11 type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003933 268.0
HKD1_k127_1364912_12 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000001559 231.0
HKD1_k127_1364912_13 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000000000001783 201.0
HKD1_k127_1364912_14 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000009111 182.0
HKD1_k127_1364912_15 Dopa 4,5-dioxygenase family K10253 - - 0.0000000000000000000000000000000000000000002257 169.0
HKD1_k127_1364912_16 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000005116 171.0
HKD1_k127_1364912_17 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000001993 170.0
HKD1_k127_1364912_18 type II secretion system K12511 - - 0.000000000000000000000000000000000000002219 156.0
HKD1_k127_1364912_19 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000007326 126.0
HKD1_k127_1364912_2 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 525.0
HKD1_k127_1364912_20 Pilus biogenesis CpaD protein (pilus_cpaD) K02281 - - 0.0000000000000000000000000473 117.0
HKD1_k127_1364912_21 Type IV leader peptidase family - - - 0.00000000000000000007613 97.0
HKD1_k127_1364912_22 Flp pilus assembly protein, pilin Flp K02651 - - 0.00000003902 57.0
HKD1_k127_1364912_24 Flp Fap pilin component K02651 - - 0.00000007376 56.0
HKD1_k127_1364912_25 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00001587 49.0
HKD1_k127_1364912_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 447.0
HKD1_k127_1364912_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 396.0
HKD1_k127_1364912_5 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 386.0
HKD1_k127_1364912_6 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 387.0
HKD1_k127_1364912_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 370.0
HKD1_k127_1364912_8 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 329.0
HKD1_k127_1364912_9 Pilus assembly protein CpaE K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002253 291.0
HKD1_k127_1385699_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1149.0
HKD1_k127_1385699_1 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 544.0
HKD1_k127_1385699_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 395.0
HKD1_k127_1385699_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 364.0
HKD1_k127_1385699_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000001477 248.0
HKD1_k127_1385699_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000001301 141.0
HKD1_k127_1385699_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000005267 138.0
HKD1_k127_1386594_0 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 516.0
HKD1_k127_1386594_1 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 383.0
HKD1_k127_1386594_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000836 368.0
HKD1_k127_1386594_3 Belongs to the 'phage' integrase family - - - 0.00000000006415 74.0
HKD1_k127_1386594_4 Bacterial-like globin K06886 - - 0.000004044 51.0
HKD1_k127_1432678_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.697e-292 907.0
HKD1_k127_1432678_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 509.0
HKD1_k127_1432678_2 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 472.0
HKD1_k127_1432678_3 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 352.0
HKD1_k127_1432678_4 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000001522 179.0
HKD1_k127_1435225_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 8.555e-288 891.0
HKD1_k127_1435225_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 8.97e-251 792.0
HKD1_k127_1435225_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 553.0
HKD1_k127_1435225_3 Amino-transferase class IV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 524.0
HKD1_k127_1435225_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 411.0
HKD1_k127_1435225_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 387.0
HKD1_k127_1435225_6 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 289.0
HKD1_k127_1435225_7 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000001021 210.0
HKD1_k127_1463805_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.167e-268 847.0
HKD1_k127_1463805_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.682e-199 640.0
HKD1_k127_1463805_10 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000001329 212.0
HKD1_k127_1463805_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000001021 177.0
HKD1_k127_1463805_12 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000000000000008049 141.0
HKD1_k127_1463805_13 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000006137 132.0
HKD1_k127_1463805_15 - - - - 0.0000000000147 73.0
HKD1_k127_1463805_2 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 499.0
HKD1_k127_1463805_3 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 485.0
HKD1_k127_1463805_4 NMT1-like family K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 451.0
HKD1_k127_1463805_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 366.0
HKD1_k127_1463805_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 381.0
HKD1_k127_1463805_7 inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 321.0
HKD1_k127_1463805_8 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002132 296.0
HKD1_k127_1463805_9 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003898 274.0
HKD1_k127_1507165_0 Major Facilitator Superfamily - - - 1.184e-239 750.0
HKD1_k127_1507165_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 606.0
HKD1_k127_1507165_10 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 311.0
HKD1_k127_1507165_11 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 305.0
HKD1_k127_1507165_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001114 289.0
HKD1_k127_1507165_13 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000222 271.0
HKD1_k127_1507165_14 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000345 251.0
HKD1_k127_1507165_15 Uncharacterised protein family (UPF0262) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001054 238.0
HKD1_k127_1507165_16 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
HKD1_k127_1507165_17 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000003155 216.0
HKD1_k127_1507165_18 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000005065 230.0
HKD1_k127_1507165_19 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000006771 211.0
HKD1_k127_1507165_2 PAS fold K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 608.0
HKD1_k127_1507165_20 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000005097 199.0
HKD1_k127_1507165_21 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000000004646 158.0
HKD1_k127_1507165_22 Cupin domain K21700 - - 0.000000000000000000000001047 107.0
HKD1_k127_1507165_23 addiction module antidote protein HigA K21498 - - 0.0000000000000000006263 89.0
HKD1_k127_1507165_24 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000006646 73.0
HKD1_k127_1507165_25 Protein of unknown function (DUF2948) - - - 0.000000000007814 65.0
HKD1_k127_1507165_26 Resolvase - - - 0.00000008698 55.0
HKD1_k127_1507165_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 486.0
HKD1_k127_1507165_4 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 449.0
HKD1_k127_1507165_5 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 405.0
HKD1_k127_1507165_6 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 359.0
HKD1_k127_1507165_7 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 340.0
HKD1_k127_1507165_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 322.0
HKD1_k127_1507165_9 COG1530 Ribonucleases G and E K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 338.0
HKD1_k127_1507995_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 3.056e-275 869.0
HKD1_k127_1507995_1 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 2.053e-196 625.0
HKD1_k127_1507995_2 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 435.0
HKD1_k127_1507995_3 COG4608 ABC-type oligopeptide transport system, ATPase component K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 426.0
HKD1_k127_1507995_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 397.0
HKD1_k127_1507995_5 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 383.0
HKD1_k127_1507995_6 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005472 293.0
HKD1_k127_1512046_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.616e-280 868.0
HKD1_k127_1512046_1 Sodium/hydrogen exchanger family K03316 - - 8.412e-246 786.0
HKD1_k127_1512046_2 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 567.0
HKD1_k127_1512046_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 457.0
HKD1_k127_1512046_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 349.0
HKD1_k127_1512046_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 340.0
HKD1_k127_1512046_6 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 303.0
HKD1_k127_1565976_0 PAS fold K01768 - 4.6.1.1 5e-324 1013.0
HKD1_k127_1565976_1 AMP-binding enzyme K12508 - 6.2.1.34 1.372e-248 784.0
HKD1_k127_1565976_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 409.0
HKD1_k127_1565976_11 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 400.0
HKD1_k127_1565976_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 379.0
HKD1_k127_1565976_13 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 361.0
HKD1_k127_1565976_14 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 364.0
HKD1_k127_1565976_15 ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 357.0
HKD1_k127_1565976_16 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 341.0
HKD1_k127_1565976_17 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 323.0
HKD1_k127_1565976_18 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 292.0
HKD1_k127_1565976_19 abc transporter K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 305.0
HKD1_k127_1565976_2 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 2.614e-241 756.0
HKD1_k127_1565976_20 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 294.0
HKD1_k127_1565976_21 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000000000000007591 163.0
HKD1_k127_1565976_22 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000177 151.0
HKD1_k127_1565976_23 - - - - 0.000000000000001647 85.0
HKD1_k127_1565976_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 9.816e-224 702.0
HKD1_k127_1565976_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 544.0
HKD1_k127_1565976_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 518.0
HKD1_k127_1565976_6 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 499.0
HKD1_k127_1565976_7 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 518.0
HKD1_k127_1565976_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 456.0
HKD1_k127_1565976_9 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 452.0
HKD1_k127_1574655_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 523.0
HKD1_k127_1574655_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
HKD1_k127_1574655_2 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000008674 185.0
HKD1_k127_1574655_3 COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.00000000000000000000000000000000005321 136.0
HKD1_k127_1574655_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000005291 128.0
HKD1_k127_1574655_5 LysE type translocator - - - 0.0000000000000000000000424 108.0
HKD1_k127_1580892_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 615.0
HKD1_k127_1580892_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 555.0
HKD1_k127_1580892_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 331.0
HKD1_k127_1580892_3 Cupin domain - - - 0.00000000007148 68.0
HKD1_k127_1597127_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 594.0
HKD1_k127_1597127_1 Helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 350.0
HKD1_k127_1597127_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 323.0
HKD1_k127_1597127_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 300.0
HKD1_k127_1597127_4 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000002625 260.0
HKD1_k127_1597127_5 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000001726 197.0
HKD1_k127_1597127_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000001103 204.0
HKD1_k127_1597127_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000004398 100.0
HKD1_k127_1646000_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 396.0
HKD1_k127_1646000_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000009167 165.0
HKD1_k127_1646000_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000008821 157.0
HKD1_k127_1646000_3 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000005775 81.0
HKD1_k127_1733281_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 540.0
HKD1_k127_1733281_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 518.0
HKD1_k127_1733281_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 437.0
HKD1_k127_1733281_3 Hydrolase CocE NonD family K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 404.0
HKD1_k127_1733281_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 351.0
HKD1_k127_1733281_5 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 357.0
HKD1_k127_1733281_6 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006976 292.0
HKD1_k127_1733281_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000672 213.0
HKD1_k127_1739914_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1420.0
HKD1_k127_1739914_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.43e-267 840.0
HKD1_k127_1739914_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 576.0
HKD1_k127_1739914_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 426.0
HKD1_k127_1739914_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 422.0
HKD1_k127_1739914_5 (LPS) heptosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 404.0
HKD1_k127_1739914_6 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 352.0
HKD1_k127_174640_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 550.0
HKD1_k127_174640_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 509.0
HKD1_k127_174640_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 485.0
HKD1_k127_174640_3 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 488.0
HKD1_k127_174640_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 421.0
HKD1_k127_174640_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 323.0
HKD1_k127_174640_6 Cytochrome c2 K08738 - - 0.00000000000000000000000000000000001642 140.0
HKD1_k127_174640_7 - - - - 0.000000000000000000000000000004286 127.0
HKD1_k127_174640_8 Transposase and inactivated K07492 - - 0.0000000000000000007296 87.0
HKD1_k127_1770788_0 Bacterial extracellular solute-binding protein - - - 1.51e-205 644.0
HKD1_k127_1770788_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 497.0
HKD1_k127_1770788_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 436.0
HKD1_k127_1770788_3 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001341 287.0
HKD1_k127_1770788_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000001247 118.0
HKD1_k127_1772327_0 cell division K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 346.0
HKD1_k127_1772327_1 Cell division protein K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006703 295.0
HKD1_k127_1772327_2 DUF218 domain - - - 0.00000000000000000000000000000000000001751 161.0
HKD1_k127_1781080_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.244e-247 773.0
HKD1_k127_1781080_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 576.0
HKD1_k127_1781080_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000003729 57.0
HKD1_k127_1781080_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 577.0
HKD1_k127_1781080_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 361.0
HKD1_k127_1781080_4 COG4942 Membrane-bound metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 357.0
HKD1_k127_1781080_5 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000396 292.0
HKD1_k127_1781080_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000001197 244.0
HKD1_k127_1781080_7 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000001242 213.0
HKD1_k127_1781080_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000001901 196.0
HKD1_k127_1781080_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000005694 139.0
HKD1_k127_1789542_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 1.582e-249 784.0
HKD1_k127_1789542_1 MmgE PrpD family protein - - - 1.851e-209 659.0
HKD1_k127_1789542_10 OmpA family - - - 0.00000000000000000000000000004584 128.0
HKD1_k127_1789542_11 PFAM DoxX family protein K15977 - - 0.0000000000000000000000001023 113.0
HKD1_k127_1789542_2 transporter, ATP-binding protein K13926 - - 8.039e-201 645.0
HKD1_k127_1789542_3 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 601.0
HKD1_k127_1789542_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 376.0
HKD1_k127_1789542_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 378.0
HKD1_k127_1789542_6 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 332.0
HKD1_k127_1789542_7 Secretion protein, HlyD K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 301.0
HKD1_k127_1789542_8 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000001401 226.0
HKD1_k127_1789542_9 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000005139 177.0
HKD1_k127_18024_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component K11690 - - 5.668e-211 671.0
HKD1_k127_18024_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 3.561e-201 636.0
HKD1_k127_18024_2 Protein of unknown function (DUF993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 540.0
HKD1_k127_18024_3 3-carboxy-cis,cis-muconate cycloisomerase K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 541.0
HKD1_k127_18024_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 434.0
HKD1_k127_18024_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 432.0
HKD1_k127_18024_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 360.0
HKD1_k127_18024_7 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 353.0
HKD1_k127_18024_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
HKD1_k127_18024_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002221 246.0
HKD1_k127_1804694_0 ABC-type dipeptide transport system periplasmic component K02035 - - 6.002e-210 664.0
HKD1_k127_1804694_1 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 531.0
HKD1_k127_1804694_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 445.0
HKD1_k127_1804694_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 438.0
HKD1_k127_1804694_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 398.0
HKD1_k127_1804694_5 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 391.0
HKD1_k127_1804694_6 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003481 276.0
HKD1_k127_1804694_7 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006798 282.0
HKD1_k127_1840345_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 301.0
HKD1_k127_1840345_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002895 243.0
HKD1_k127_1840345_2 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000001606 206.0
HKD1_k127_1840345_3 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000166 167.0
HKD1_k127_1868902_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 501.0
HKD1_k127_1868902_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 465.0
HKD1_k127_1868902_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 403.0
HKD1_k127_1868902_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001449 278.0
HKD1_k127_1868902_4 - - - - 0.0000000000000000000000000000000000000000000000009045 179.0
HKD1_k127_1868902_5 transcription regulator containing HTH domain K18831 - - 0.0000000000000000000000000000169 128.0
HKD1_k127_1868902_7 protein conserved in bacteria (DUF2136) K19166 - - 0.0000000000000005767 78.0
HKD1_k127_1874757_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 6.179e-273 846.0
HKD1_k127_1874757_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 614.0
HKD1_k127_1874757_10 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 382.0
HKD1_k127_1874757_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
HKD1_k127_1874757_12 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 374.0
HKD1_k127_1874757_13 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 304.0
HKD1_k127_1874757_14 COG2199 FOG GGDEF domain K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 302.0
HKD1_k127_1874757_15 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 290.0
HKD1_k127_1874757_16 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000122 247.0
HKD1_k127_1874757_17 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000001 202.0
HKD1_k127_1874757_18 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.000000000000000000000000000000001459 131.0
HKD1_k127_1874757_2 Binding-protein-dependent transport system inner membrane component K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 535.0
HKD1_k127_1874757_3 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 506.0
HKD1_k127_1874757_4 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 488.0
HKD1_k127_1874757_5 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 452.0
HKD1_k127_1874757_6 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 441.0
HKD1_k127_1874757_7 N-terminal TM domain of oligopeptide transport permease C K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 430.0
HKD1_k127_1874757_8 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 422.0
HKD1_k127_1874757_9 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 399.0
HKD1_k127_1926229_0 Reductase C-terminal K05297 - 1.18.1.1 3.478e-242 759.0
HKD1_k127_1926229_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.836e-218 688.0
HKD1_k127_1926229_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000003439 214.0
HKD1_k127_1926229_11 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000916 193.0
HKD1_k127_1926229_12 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000000004948 168.0
HKD1_k127_1926229_13 - - - - 0.00000000000000000000000003239 111.0
HKD1_k127_1926229_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 556.0
HKD1_k127_1926229_3 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 465.0
HKD1_k127_1926229_4 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 371.0
HKD1_k127_1926229_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 368.0
HKD1_k127_1926229_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 328.0
HKD1_k127_1926229_7 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 322.0
HKD1_k127_1926229_8 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
HKD1_k127_1926229_9 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000568 228.0
HKD1_k127_1949845_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 540.0
HKD1_k127_1949845_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 512.0
HKD1_k127_1949845_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 387.0
HKD1_k127_1949845_3 Phosphonate ABC transporter K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 326.0
HKD1_k127_1949845_4 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 291.0
HKD1_k127_1949845_5 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005131 234.0
HKD1_k127_1949845_7 phosphonate ABC transporter K02044 - - 0.00000000000000000000002872 102.0
HKD1_k127_1949845_8 GYD domain - - - 0.000000000000000000000112 109.0
HKD1_k127_1949845_9 Phosphonate ABC transporter K02044 - - 0.0005401 43.0
HKD1_k127_196059_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 443.0
HKD1_k127_196059_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000005741 190.0
HKD1_k127_196059_2 Domain of unknown function (DUF1849) - - - 0.000000000000000000000000000000000000000000000001404 194.0
HKD1_k127_1995789_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1174.0
HKD1_k127_1995789_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 8.763e-215 673.0
HKD1_k127_1995789_10 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000009722 231.0
HKD1_k127_1995789_11 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000001058 165.0
HKD1_k127_1995789_12 PAS domain - - - 0.000000000000000000000000000000000000299 146.0
HKD1_k127_1995789_13 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000004067 134.0
HKD1_k127_1995789_14 Transposase DDE domain K07492 - - 0.000000000000000000001319 98.0
HKD1_k127_1995789_15 Transposase DDE domain - - - 0.000000000000002312 76.0
HKD1_k127_1995789_16 Transposase DDE domain - - - 0.00000000000002056 76.0
HKD1_k127_1995789_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 566.0
HKD1_k127_1995789_3 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 447.0
HKD1_k127_1995789_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 436.0
HKD1_k127_1995789_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 327.0
HKD1_k127_1995789_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 319.0
HKD1_k127_1995789_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 316.0
HKD1_k127_1995789_8 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 302.0
HKD1_k127_1995789_9 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001418 269.0
HKD1_k127_2004820_0 COG2873 O-acetylhomoserine sulfhydrylase - - - 3.047e-232 725.0
HKD1_k127_2004820_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 473.0
HKD1_k127_2004820_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 382.0
HKD1_k127_2004820_3 protein conserved in bacteria K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 291.0
HKD1_k127_2004820_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001097 305.0
HKD1_k127_2004820_5 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000004931 205.0
HKD1_k127_2004820_6 the major facilitator superfamily - - - 0.000000000000000000000000000000001046 132.0
HKD1_k127_2004820_7 Apolipoprotein A1/A4/E domain - - - 0.00000000002995 74.0
HKD1_k127_2004820_9 - - - - 0.0007178 45.0
HKD1_k127_203262_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.752e-216 678.0
HKD1_k127_203262_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 310.0
HKD1_k127_203262_2 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 304.0
HKD1_k127_203262_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000001804 194.0
HKD1_k127_203262_4 Cold shock protein domain - - - 0.00000000000000000000000000000000000002779 151.0
HKD1_k127_2038515_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 548.0
HKD1_k127_2038515_1 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 511.0
HKD1_k127_2038515_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009103 259.0
HKD1_k127_2038515_11 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005825 262.0
HKD1_k127_2038515_12 COG1247 Sortase and related acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000002634 226.0
HKD1_k127_2038515_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000005221 217.0
HKD1_k127_2038515_14 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000003385 194.0
HKD1_k127_2038515_15 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000001633 198.0
HKD1_k127_2038515_16 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000107 174.0
HKD1_k127_2038515_17 GYD domain - - - 0.00000000000000000000000000000000000000001447 154.0
HKD1_k127_2038515_18 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000001982 163.0
HKD1_k127_2038515_19 response regulator K13589 - - 0.00000000000000000000000000000000000000004385 158.0
HKD1_k127_2038515_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 460.0
HKD1_k127_2038515_20 TIGRFAM TIGR00645 family protein - - - 0.00000000000000000000000000000000000000005057 157.0
HKD1_k127_2038515_21 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000001652 133.0
HKD1_k127_2038515_22 - - - - 0.00000000000000000000000000002877 122.0
HKD1_k127_2038515_23 Glycine zipper - - - 0.000000000000006874 83.0
HKD1_k127_2038515_3 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 422.0
HKD1_k127_2038515_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 416.0
HKD1_k127_2038515_5 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 408.0
HKD1_k127_2038515_6 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 417.0
HKD1_k127_2038515_7 mandelate racemase muconate lactonizing K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 394.0
HKD1_k127_2038515_8 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 322.0
HKD1_k127_2038515_9 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 308.0
HKD1_k127_2078292_0 Sulfate permease family - - - 1.765e-216 687.0
HKD1_k127_2078292_1 amino acid K03294,K03758,K03759 - - 2.499e-215 678.0
HKD1_k127_2078292_2 Arginine K01478 - 3.5.3.6 3.925e-196 617.0
HKD1_k127_2078292_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 487.0
HKD1_k127_2078292_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 406.0
HKD1_k127_2078292_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 389.0
HKD1_k127_2078292_6 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000019 182.0
HKD1_k127_2078292_7 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000005793 153.0
HKD1_k127_2078292_8 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000002749 141.0
HKD1_k127_2095090_0 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 520.0
HKD1_k127_2095090_1 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 505.0
HKD1_k127_2095090_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 466.0
HKD1_k127_2095090_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 357.0
HKD1_k127_2095090_4 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000001331 198.0
HKD1_k127_2106292_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1181.0
HKD1_k127_2106292_1 Arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 541.0
HKD1_k127_2106292_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 471.0
HKD1_k127_2106292_3 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 319.0
HKD1_k127_2106292_4 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000368 169.0
HKD1_k127_2106292_5 FAD binding domain in molybdopterin dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000003966 175.0
HKD1_k127_2113861_0 formamidase K01455 - 3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 557.0
HKD1_k127_2113861_1 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 397.0
HKD1_k127_2113861_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004398 263.0
HKD1_k127_2113861_3 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000003225 207.0
HKD1_k127_2134155_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 406.0
HKD1_k127_2134155_1 NUDIX domain K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 327.0
HKD1_k127_2134155_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 320.0
HKD1_k127_2134155_3 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001672 295.0
HKD1_k127_2134155_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000001195 173.0
HKD1_k127_2134155_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000001763 158.0
HKD1_k127_2134155_6 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000501 160.0
HKD1_k127_2134155_7 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000005496 121.0
HKD1_k127_2134155_8 - - - - 0.0000000000000000000001197 102.0
HKD1_k127_2134155_9 - - - - 0.000000000000002245 86.0
HKD1_k127_2135936_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 7.976e-250 782.0
HKD1_k127_2135936_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 588.0
HKD1_k127_2135936_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 574.0
HKD1_k127_2135936_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 490.0
HKD1_k127_2135936_4 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 344.0
HKD1_k127_2135936_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 319.0
HKD1_k127_2135936_6 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000005678 213.0
HKD1_k127_2135936_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000007255 198.0
HKD1_k127_2135936_8 Protein of unknown function (DUF559) - - - 0.0000000000000000000000005579 120.0
HKD1_k127_2138628_0 FAD dependent oxidoreductase central domain K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1383.0
HKD1_k127_2138628_1 NADH:flavin oxidoreductase / NADH oxidase family K21833 - - 0.0 1062.0
HKD1_k127_2138628_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 347.0
HKD1_k127_2138628_3 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 337.0
HKD1_k127_2138628_4 FAD binding domain in molybdopterin dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007958 261.0
HKD1_k127_2138628_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000004554 188.0
HKD1_k127_2138628_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000005755 155.0
HKD1_k127_2138628_7 racemase activity, acting on amino acids and derivatives - - - 0.00000000000000000000211 100.0
HKD1_k127_2154899_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 394.0
HKD1_k127_2154899_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 361.0
HKD1_k127_2154899_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 320.0
HKD1_k127_2154899_3 sulfuric ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002125 256.0
HKD1_k127_2184197_0 ABC-type uncharacterized transport system - - - 1.191e-245 777.0
HKD1_k127_2184197_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 1.341e-212 675.0
HKD1_k127_2184197_10 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000005071 215.0
HKD1_k127_2184197_11 - - - - 0.00000000000000000000000001809 117.0
HKD1_k127_2184197_12 D-arabinono-1,4-lactone oxidase K00103 - 1.1.3.8 0.000000000000000000003064 108.0
HKD1_k127_2184197_13 Protein of unknown function (DUF1289) K06938 - - 0.00000000001074 77.0
HKD1_k127_2184197_14 - - - - 0.0000718 50.0
HKD1_k127_2184197_2 Mechanosensitive ion channel K22044 - - 2.273e-197 650.0
HKD1_k127_2184197_3 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 435.0
HKD1_k127_2184197_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 392.0
HKD1_k127_2184197_5 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 371.0
HKD1_k127_2184197_6 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 349.0
HKD1_k127_2184197_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002288 295.0
HKD1_k127_2184197_8 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001081 296.0
HKD1_k127_2184197_9 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001118 239.0
HKD1_k127_218964_0 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
HKD1_k127_218964_1 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001462 279.0
HKD1_k127_218964_2 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001857 252.0
HKD1_k127_218964_3 protein conserved in bacteria K09973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 257.0
HKD1_k127_218964_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000007702 211.0
HKD1_k127_218964_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000001985 155.0
HKD1_k127_218964_6 PFAM alpha beta hydrolase fold - - - 0.0000000000000000001518 99.0
HKD1_k127_223115_0 Sugar (and other) transporter - - - 1.326e-207 653.0
HKD1_k127_223115_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 523.0
HKD1_k127_223115_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 359.0
HKD1_k127_223115_3 Histidine kinase K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 286.0
HKD1_k127_223115_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000006582 253.0
HKD1_k127_223115_5 carboxylic ester hydrolase activity - - - 0.000000004833 64.0
HKD1_k127_2260091_0 HELICc2 K03722 - 3.6.4.12 0.0 1194.0
HKD1_k127_2260091_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000898 271.0
HKD1_k127_2260091_2 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000139 181.0
HKD1_k127_2260091_3 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000009672 113.0
HKD1_k127_2267977_0 Penicillin amidase K01434 - 3.5.1.11 1.702e-273 862.0
HKD1_k127_2267977_1 Belongs to the aldehyde dehydrogenase family - - - 1.419e-251 783.0
HKD1_k127_2267977_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 454.0
HKD1_k127_2267977_3 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001335 267.0
HKD1_k127_2270047_0 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.0 1254.0
HKD1_k127_2270047_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 571.0
HKD1_k127_2270047_10 COG0835 Chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000000000000000000000000000000001406 223.0
HKD1_k127_2270047_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000000006967 200.0
HKD1_k127_2270047_12 Histidine phosphotransferase C-terminal domain K13588 - - 0.0000000000000000000000000000000000000000000000000002454 198.0
HKD1_k127_2270047_13 transmembrane signaling receptor activity K03406,K13243 - 3.1.4.52 0.000000000000000000000000000000001894 147.0
HKD1_k127_2270047_14 positive regulation of growth - - - 0.00001016 52.0
HKD1_k127_2270047_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 493.0
HKD1_k127_2270047_3 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 357.0
HKD1_k127_2270047_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 353.0
HKD1_k127_2270047_5 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
HKD1_k127_2270047_6 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
HKD1_k127_2270047_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001985 281.0
HKD1_k127_2270047_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000303 251.0
HKD1_k127_2270047_9 COG0784 FOG CheY-like receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000002181 205.0
HKD1_k127_2289146_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.692e-294 911.0
HKD1_k127_2289146_1 elongator protein 3 miab nifb - - - 5.058e-237 756.0
HKD1_k127_2289146_10 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000009801 215.0
HKD1_k127_2289146_11 COG0790 FOG TPR repeat, SEL1 subfamily K07126,K13582 - - 0.000000000000000000000000000000000000000000000000006166 197.0
HKD1_k127_2289146_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 607.0
HKD1_k127_2289146_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 525.0
HKD1_k127_2289146_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 342.0
HKD1_k127_2289146_5 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 331.0
HKD1_k127_2289146_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 315.0
HKD1_k127_2289146_7 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 304.0
HKD1_k127_2289146_8 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 300.0
HKD1_k127_2289146_9 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001072 252.0
HKD1_k127_23694_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 504.0
HKD1_k127_23694_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 330.0
HKD1_k127_23694_2 energy transducer activity K03832 - - 0.000001723 57.0
HKD1_k127_2370133_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.358e-255 799.0
HKD1_k127_2370133_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.436e-248 772.0
HKD1_k127_2382466_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1185.0
HKD1_k127_2382466_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 460.0
HKD1_k127_2382466_10 - - - - 0.0000000007374 69.0
HKD1_k127_2382466_11 Immunity protein 52 - - - 0.00011 53.0
HKD1_k127_2382466_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 405.0
HKD1_k127_2382466_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005663 284.0
HKD1_k127_2382466_4 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002461 255.0
HKD1_k127_2382466_5 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000008438 198.0
HKD1_k127_2382466_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000001208 187.0
HKD1_k127_2382466_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000004278 135.0
HKD1_k127_2382466_8 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000001431 136.0
HKD1_k127_2382466_9 - - - - 0.000000000000000000000001171 119.0
HKD1_k127_2389050_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 1.114e-201 633.0
HKD1_k127_2389050_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 6.149e-195 617.0
HKD1_k127_2389050_10 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000003217 147.0
HKD1_k127_2389050_11 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000001627 136.0
HKD1_k127_2389050_12 - - - - 0.000009408 54.0
HKD1_k127_2389050_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 420.0
HKD1_k127_2389050_3 Amino-transferase class IV K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 390.0
HKD1_k127_2389050_4 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 354.0
HKD1_k127_2389050_5 methylisocitrate lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 329.0
HKD1_k127_2389050_6 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001954 274.0
HKD1_k127_2389050_7 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000001815 250.0
HKD1_k127_2389050_8 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000001859 183.0
HKD1_k127_2389050_9 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000001748 163.0
HKD1_k127_2423468_0 PrkA AAA domain K07180 - - 4.295e-275 849.0
HKD1_k127_2423468_1 SpoVR like protein K06415 - - 3.966e-249 787.0
HKD1_k127_2423468_2 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 516.0
HKD1_k127_2423468_3 acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine K02029 - - 0.00000000000000000000000000000000000000005524 160.0
HKD1_k127_2425560_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 5.493e-223 714.0
HKD1_k127_2425560_1 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 1e-203 646.0
HKD1_k127_2425560_10 PFAM thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000002036 100.0
HKD1_k127_2425560_11 CoA binding domain K01895,K09181 - 6.2.1.1 0.00000000000000006748 94.0
HKD1_k127_2425560_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 461.0
HKD1_k127_2425560_3 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 362.0
HKD1_k127_2425560_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 321.0
HKD1_k127_2425560_5 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001053 279.0
HKD1_k127_2425560_6 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000001196 229.0
HKD1_k127_2425560_7 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000003229 187.0
HKD1_k127_2425560_8 gntR family K05799 - - 0.0000000000000000000000000000000000000000000085 175.0
HKD1_k127_2425560_9 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000121 98.0
HKD1_k127_2427196_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000228 267.0
HKD1_k127_2427196_1 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.0000000000000000000002836 106.0
HKD1_k127_2427196_2 PKS_KR - - - 0.0000000000002873 79.0
HKD1_k127_2427196_3 polyketide synthase K04786 - - 0.000000000001364 77.0
HKD1_k127_2478679_0 Peptidase family M41 K03798 - - 7.861e-272 850.0
HKD1_k127_2478679_1 transport system fused permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 506.0
HKD1_k127_2478679_2 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 390.0
HKD1_k127_2478679_3 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 307.0
HKD1_k127_2478679_4 TRAP transporter solute receptor TAXI family protein K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 293.0
HKD1_k127_2478679_5 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000002951 243.0
HKD1_k127_2478679_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000000000000000000000254 215.0
HKD1_k127_2478679_7 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000009023 181.0
HKD1_k127_2478679_8 AMP-binding enzyme - - - 0.00000000000000000000003662 115.0
HKD1_k127_2478679_9 Putative zinc- or iron-chelating domain - - - 0.00000000000136 79.0
HKD1_k127_2488614_0 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 445.0
HKD1_k127_2488614_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 319.0
HKD1_k127_2490_0 Fumarate hydratase (Fumerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 497.0
HKD1_k127_2490_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 454.0
HKD1_k127_2490_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 441.0
HKD1_k127_2490_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 421.0
HKD1_k127_2490_4 Fumarase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 300.0
HKD1_k127_2490_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000005079 96.0
HKD1_k127_249357_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1350.0
HKD1_k127_249357_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1183.0
HKD1_k127_249357_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 327.0
HKD1_k127_249357_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 316.0
HKD1_k127_249357_12 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009077 295.0
HKD1_k127_249357_13 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005994 265.0
HKD1_k127_249357_14 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
HKD1_k127_249357_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000006562 216.0
HKD1_k127_249357_16 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000001114 169.0
HKD1_k127_249357_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000117 166.0
HKD1_k127_249357_18 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000002466 143.0
HKD1_k127_249357_2 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1015.0
HKD1_k127_249357_20 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000421 70.0
HKD1_k127_249357_21 - - - - 0.0000006437 54.0
HKD1_k127_249357_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.227e-256 796.0
HKD1_k127_249357_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.379e-254 787.0
HKD1_k127_249357_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.116e-219 696.0
HKD1_k127_249357_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 545.0
HKD1_k127_249357_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 508.0
HKD1_k127_249357_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 338.0
HKD1_k127_249357_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 329.0
HKD1_k127_250832_0 COG0457 FOG TPR repeat - - - 1.293e-241 758.0
HKD1_k127_250832_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.202e-200 649.0
HKD1_k127_250832_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000001147 241.0
HKD1_k127_250832_11 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000004232 242.0
HKD1_k127_250832_12 branched-chain amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000002376 232.0
HKD1_k127_250832_13 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000001103 227.0
HKD1_k127_250832_14 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000298 196.0
HKD1_k127_250832_15 KR domain - - - 0.0000000000000000000000000000000000000001296 160.0
HKD1_k127_250832_16 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000005438 113.0
HKD1_k127_250832_17 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00000525 50.0
HKD1_k127_250832_2 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 572.0
HKD1_k127_250832_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 475.0
HKD1_k127_250832_4 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 393.0
HKD1_k127_250832_5 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 372.0
HKD1_k127_250832_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 364.0
HKD1_k127_250832_7 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007533 276.0
HKD1_k127_250832_8 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HKD1_k127_250832_9 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000208 244.0
HKD1_k127_2517204_0 Phosphopantetheine attachment site K00666 - - 2.318e-285 907.0
HKD1_k127_2517204_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 2.961e-283 912.0
HKD1_k127_2517204_10 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000003538 176.0
HKD1_k127_2517204_11 tRNA modification K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000003949 176.0
HKD1_k127_2517204_12 GYD domain - - - 0.0000000000000000000000000000000000000000006428 160.0
HKD1_k127_2517204_13 AAA domain - - - 0.000000000000000000000000000000000000000008516 158.0
HKD1_k127_2517204_14 - - - - 0.0000000004926 64.0
HKD1_k127_2517204_15 Amidohydrolase family - - - 0.000002547 58.0
HKD1_k127_2517204_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 546.0
HKD1_k127_2517204_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 528.0
HKD1_k127_2517204_4 PFAM NAD dependent epimerase dehydratase family K18981 - 1.1.1.203 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 438.0
HKD1_k127_2517204_5 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 435.0
HKD1_k127_2517204_6 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 298.0
HKD1_k127_2517204_7 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 289.0
HKD1_k127_2517204_8 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000797 237.0
HKD1_k127_2517204_9 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000003572 221.0
HKD1_k127_2523583_0 Adenylate cyclase K01768 - 4.6.1.1 1.957e-240 756.0
HKD1_k127_2523583_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 560.0
HKD1_k127_2523583_10 transduction histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000003487 235.0
HKD1_k127_2523583_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000008541 241.0
HKD1_k127_2523583_12 Peptidase A4 family - - - 0.0000000000000000000000000000000000000000000000000000000000001202 226.0
HKD1_k127_2523583_13 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000007082 217.0
HKD1_k127_2523583_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000001249 197.0
HKD1_k127_2523583_15 - - - - 0.0000000000000000000000000000000000000000000000002319 202.0
HKD1_k127_2523583_16 PAS domain - - - 0.000000000000000000000000000000000000000000002279 169.0
HKD1_k127_2523583_17 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000000005377 172.0
HKD1_k127_2523583_18 Putative peptidoglycan binding domain - - - 0.0000000002452 69.0
HKD1_k127_2523583_19 - - - - 0.000000001504 67.0
HKD1_k127_2523583_2 succinate dehydrogenase fumarate reductase, flavoprotein subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 559.0
HKD1_k127_2523583_20 - - - - 0.00003207 54.0
HKD1_k127_2523583_21 Peptidoglycan-binding domain 1 protein - - - 0.0001416 53.0
HKD1_k127_2523583_22 Glycine zipper 2TM domain - - - 0.0008753 49.0
HKD1_k127_2523583_3 pilus assembly protein ATPase CpaF K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 533.0
HKD1_k127_2523583_4 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 429.0
HKD1_k127_2523583_5 COG1062 Zn-dependent alcohol dehydrogenases, class III K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 373.0
HKD1_k127_2523583_6 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 299.0
HKD1_k127_2523583_7 membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004848 253.0
HKD1_k127_2523583_8 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001393 255.0
HKD1_k127_2523583_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000006741 242.0
HKD1_k127_252415_0 malic enzyme K00029 - 1.1.1.40 0.0 1172.0
HKD1_k127_252415_1 This protein is involved in the repair of mismatches in DNA K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 530.0
HKD1_k127_252415_2 PBP superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 515.0
HKD1_k127_252415_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 464.0
HKD1_k127_252415_4 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 449.0
HKD1_k127_252415_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 439.0
HKD1_k127_252415_6 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 426.0
HKD1_k127_252415_7 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 357.0
HKD1_k127_252415_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 355.0
HKD1_k127_252415_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 332.0
HKD1_k127_254340_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.977e-306 961.0
HKD1_k127_254340_1 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 1.657e-195 620.0
HKD1_k127_254340_10 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009104 299.0
HKD1_k127_254340_11 Cupin domain K21700 - - 0.000000000000000000000000001573 114.0
HKD1_k127_254340_2 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 578.0
HKD1_k127_254340_3 Zn-dependent protease, contains TPR repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 526.0
HKD1_k127_254340_4 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 404.0
HKD1_k127_254340_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 419.0
HKD1_k127_254340_6 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 307.0
HKD1_k127_254340_7 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 299.0
HKD1_k127_254340_8 Belongs to the UPF0271 (lamB) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 300.0
HKD1_k127_254340_9 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004661 277.0
HKD1_k127_2611023_0 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 578.0
HKD1_k127_2611023_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 421.0
HKD1_k127_2611023_2 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000699 278.0
HKD1_k127_2611023_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001821 250.0
HKD1_k127_2612961_0 Stimulus-sensing domain K14980 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 517.0
HKD1_k127_2612961_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 382.0
HKD1_k127_2612961_2 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000000000000000108 239.0
HKD1_k127_2612961_3 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.0000000000000000000000000000000000000000000002392 171.0
HKD1_k127_2612961_4 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.000000000000000000000000002132 124.0
HKD1_k127_2618551_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1202.0
HKD1_k127_2618551_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.435e-257 802.0
HKD1_k127_2618551_10 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000009508 179.0
HKD1_k127_2618551_11 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000002687 178.0
HKD1_k127_2618551_12 protein conserved in bacteria - - - 0.000000000000000000000001355 122.0
HKD1_k127_2618551_13 COG0642 Signal transduction histidine kinase K14980 - 2.7.13.3 0.000000000000000000006001 100.0
HKD1_k127_2618551_14 Zinc-finger domain - - - 0.0000000000000000001943 91.0
HKD1_k127_2618551_15 - - - - 0.000267 45.0
HKD1_k127_2618551_2 Rieske [2Fe-2S] domain K21323 - 1.14.13.229,1.14.19.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 560.0
HKD1_k127_2618551_3 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 499.0
HKD1_k127_2618551_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 422.0
HKD1_k127_2618551_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 388.0
HKD1_k127_2618551_6 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 387.0
HKD1_k127_2618551_7 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 400.0
HKD1_k127_2618551_8 Lysophospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 332.0
HKD1_k127_2618551_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001725 282.0
HKD1_k127_2634284_0 Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 387.0
HKD1_k127_2634284_1 Phage capsid family - - - 0.000000000000000000000000000000000000000000000000139 190.0
HKD1_k127_2634284_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000144 156.0
HKD1_k127_2634284_4 - - - - 0.00000002186 65.0
HKD1_k127_2634284_5 Transcriptional regulator K07733 - - 0.00002074 52.0
HKD1_k127_263479_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 608.0
HKD1_k127_263479_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000003893 230.0
HKD1_k127_263479_2 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000003631 226.0
HKD1_k127_263479_3 - - - - 0.0000000000000000000000000000007364 131.0
HKD1_k127_263479_4 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000008488 103.0
HKD1_k127_2641727_0 Thiolase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 488.0
HKD1_k127_2641727_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 356.0
HKD1_k127_2641727_2 Enoyl-CoA hydratase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003646 277.0
HKD1_k127_2641727_3 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000002262 186.0
HKD1_k127_2641727_4 CoA binding domain - - - 0.000000000000000000000000000000000000000003743 158.0
HKD1_k127_2641727_5 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000043 124.0
HKD1_k127_2666158_0 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002105 260.0
HKD1_k127_2666158_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000163 261.0
HKD1_k127_2666158_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
HKD1_k127_2666158_3 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000493 242.0
HKD1_k127_2666158_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000008925 171.0
HKD1_k127_2724354_0 Hydantoinase B/oxoprolinase - - - 0.0 1001.0
HKD1_k127_2724354_1 Amidohydrolase family - - - 4.902e-196 617.0
HKD1_k127_2724354_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 559.0
HKD1_k127_2724354_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 373.0
HKD1_k127_2724354_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 371.0
HKD1_k127_2724354_5 TIR domain - - - 0.00000000000000000000000000000005429 136.0
HKD1_k127_2724354_6 Protein of unknown function (DUF1348) - - - 0.000000000000000000000000000007447 123.0
HKD1_k127_2724354_7 - - - - 0.00000000000000000000003306 104.0
HKD1_k127_2724354_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.0004512 44.0
HKD1_k127_2724354_9 radical SAM K06871 - - 0.0005997 43.0
HKD1_k127_2727911_0 Respiratory nitrate reductase alpha N-terminal K00370 - 1.7.5.1 0.0 2093.0
HKD1_k127_2727911_1 Major Facilitator Superfamily K02575 - - 0.0 1223.0
HKD1_k127_2727911_2 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 4.168e-277 874.0
HKD1_k127_2727911_3 Major Facilitator Superfamily - - - 2.955e-202 655.0
HKD1_k127_2727911_4 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 317.0
HKD1_k127_2727911_5 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 300.0
HKD1_k127_2727911_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 302.0
HKD1_k127_2727911_7 Peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000009312 249.0
HKD1_k127_2727911_8 Nitrate reductase delta subunit K00373 - - 0.00000000000000000000000000000000000000000000001284 189.0
HKD1_k127_2727911_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K13642 - - 0.00000000000000000000000000000000000000000000001724 179.0
HKD1_k127_2737480_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 6.267e-197 623.0
HKD1_k127_2737480_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 358.0
HKD1_k127_2737480_2 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 344.0
HKD1_k127_2737480_3 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000855 265.0
HKD1_k127_2737480_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000003177 194.0
HKD1_k127_2744521_0 AMP-binding enzyme C-terminal domain K12507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 610.0
HKD1_k127_2744521_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 387.0
HKD1_k127_2744521_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.000000000000000000000000000000008568 137.0
HKD1_k127_2744521_11 Immunity protein 52 - - - 0.0000000000000003111 81.0
HKD1_k127_2744521_12 - - - - 0.000000003033 66.0
HKD1_k127_2744521_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 328.0
HKD1_k127_2744521_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001596 276.0
HKD1_k127_2744521_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002328 267.0
HKD1_k127_2744521_5 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001027 252.0
HKD1_k127_2744521_6 ABC transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007807 245.0
HKD1_k127_2744521_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000009039 201.0
HKD1_k127_2744521_8 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000005348 170.0
HKD1_k127_2744521_9 oxidation-reduction process - - - 0.0000000000000000000000000000000003521 138.0
HKD1_k127_2763180_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1024.0
HKD1_k127_2763180_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 3.777e-244 790.0
HKD1_k127_2763180_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 372.0
HKD1_k127_2763180_11 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 331.0
HKD1_k127_2763180_12 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001892 275.0
HKD1_k127_2763180_13 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000173 270.0
HKD1_k127_2763180_14 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002119 264.0
HKD1_k127_2763180_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003873 254.0
HKD1_k127_2763180_16 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001909 243.0
HKD1_k127_2763180_17 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000003235 237.0
HKD1_k127_2763180_18 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000008126 201.0
HKD1_k127_2763180_19 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000000000000001701 186.0
HKD1_k127_2763180_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.126e-201 636.0
HKD1_k127_2763180_20 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000001867 194.0
HKD1_k127_2763180_21 TIGRFAM protein TolA - - - 0.000000000000000000000000000000000000000000000000007714 192.0
HKD1_k127_2763180_22 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000003622 168.0
HKD1_k127_2763180_23 thioesterase K07107 - - 0.000000000000000000000000000000000000002002 167.0
HKD1_k127_2763180_3 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 618.0
HKD1_k127_2763180_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 537.0
HKD1_k127_2763180_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 457.0
HKD1_k127_2763180_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 398.0
HKD1_k127_2763180_7 COG0811 Biopolymer transport proteins K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 387.0
HKD1_k127_2763180_8 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 384.0
HKD1_k127_2763180_9 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 369.0
HKD1_k127_2767305_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.1e-280 887.0
HKD1_k127_2767305_1 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 421.0
HKD1_k127_2767305_10 COG1846 Transcriptional regulators - - - 0.00000000000000000000000000006284 122.0
HKD1_k127_2767305_11 cheY-homologous receiver domain - - - 0.00000000000000000049 95.0
HKD1_k127_2767305_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 375.0
HKD1_k127_2767305_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
HKD1_k127_2767305_4 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 314.0
HKD1_k127_2767305_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 303.0
HKD1_k127_2767305_6 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000038 252.0
HKD1_k127_2767305_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000000000001477 209.0
HKD1_k127_2767305_8 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000006097 181.0
HKD1_k127_2767305_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000007718 164.0
HKD1_k127_2772746_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 485.0
HKD1_k127_2772746_1 V4R - - - 0.000000000000000000000000000000000000000001208 162.0
HKD1_k127_2772746_2 PAS domain - - - 0.000000000000000000000000000000000004884 143.0
HKD1_k127_2772746_3 Terminase small subunit K07474 - - 0.00000000000000000005663 95.0
HKD1_k127_2772746_4 Predicted integral membrane protein (DUF2189) - - - 0.00000000000002176 73.0
HKD1_k127_2819462_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K03418 - 3.5.1.56 0.0 1015.0
HKD1_k127_2819462_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 5.055e-257 799.0
HKD1_k127_2819462_10 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 504.0
HKD1_k127_2819462_11 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 497.0
HKD1_k127_2819462_12 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 474.0
HKD1_k127_2819462_13 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 461.0
HKD1_k127_2819462_14 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 433.0
HKD1_k127_2819462_15 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 420.0
HKD1_k127_2819462_16 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 417.0
HKD1_k127_2819462_17 Succinylglutamate desuccinylase / Aspartoacylase family K15784 - 3.5.1.125 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 417.0
HKD1_k127_2819462_18 Amino-transferase class IV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 422.0
HKD1_k127_2819462_19 Pyridoxal-phosphate dependent enzyme K05396,K17950 - 4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 412.0
HKD1_k127_2819462_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 6.466e-257 823.0
HKD1_k127_2819462_20 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 388.0
HKD1_k127_2819462_21 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 396.0
HKD1_k127_2819462_22 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 371.0
HKD1_k127_2819462_23 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 358.0
HKD1_k127_2819462_24 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 352.0
HKD1_k127_2819462_25 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 325.0
HKD1_k127_2819462_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 275.0
HKD1_k127_2819462_27 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001504 265.0
HKD1_k127_2819462_28 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000003884 213.0
HKD1_k127_2819462_29 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000135 203.0
HKD1_k127_2819462_3 COG2217 Cation transport ATPase K01533 - 3.6.3.4 7.242e-257 823.0
HKD1_k127_2819462_31 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000001055 148.0
HKD1_k127_2819462_32 FixH - - - 0.0000000000000000000000000005893 121.0
HKD1_k127_2819462_33 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000003652 115.0
HKD1_k127_2819462_34 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000000001068 74.0
HKD1_k127_2819462_4 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 5.357e-246 771.0
HKD1_k127_2819462_5 Aminotransferase class-III - - - 1.513e-216 680.0
HKD1_k127_2819462_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.839e-205 646.0
HKD1_k127_2819462_7 Nitrogen fixation protein fixG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 568.0
HKD1_k127_2819462_8 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 550.0
HKD1_k127_2819462_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 508.0
HKD1_k127_282615_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 576.0
HKD1_k127_282615_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 540.0
HKD1_k127_282615_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 532.0
HKD1_k127_282615_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 409.0
HKD1_k127_282615_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 348.0
HKD1_k127_282615_5 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 331.0
HKD1_k127_282615_6 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000002835 195.0
HKD1_k127_282615_7 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000001115 186.0
HKD1_k127_282615_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000002458 144.0
HKD1_k127_282615_9 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000008137 142.0
HKD1_k127_2826384_0 Hydantoinase/oxoprolinase - - - 0.0 1116.0
HKD1_k127_2826384_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 616.0
HKD1_k127_2826384_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 447.0
HKD1_k127_2826384_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 426.0
HKD1_k127_2826384_4 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 387.0
HKD1_k127_2826384_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 392.0
HKD1_k127_2826384_6 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000006941 212.0
HKD1_k127_2826384_7 Hydantoinase B/oxoprolinase - - - 0.000000000000000000000000000000000000000005437 156.0
HKD1_k127_2864529_0 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 6.339e-257 799.0
HKD1_k127_2864529_1 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 432.0
HKD1_k127_2864529_2 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 355.0
HKD1_k127_2864529_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 293.0
HKD1_k127_2864529_4 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000003275 161.0
HKD1_k127_2933978_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.291e-212 673.0
HKD1_k127_2933978_1 protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 619.0
HKD1_k127_2933978_2 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 539.0
HKD1_k127_2933978_3 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000004257 217.0
HKD1_k127_2933978_4 Ribbon-helix-helix domain - - - 0.0000000000000000001435 93.0
HKD1_k127_29793_0 Bacterial extracellular solute-binding protein K05813 - - 5.128e-197 621.0
HKD1_k127_29793_1 Binding-protein-dependent transport system inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 439.0
HKD1_k127_29793_2 Binding-protein-dependent transport system inner membrane component K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 432.0
HKD1_k127_29793_3 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 291.0
HKD1_k127_29793_4 Bacterial extracellular solute-binding protein - - - 0.000000000003179 78.0
HKD1_k127_3013796_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2458.0
HKD1_k127_3013796_1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 3.482e-246 766.0
HKD1_k127_3013796_10 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000001114 162.0
HKD1_k127_3013796_11 - - - - 0.00000000004244 70.0
HKD1_k127_3013796_12 OstA-like protein K09774 - - 0.00000002397 65.0
HKD1_k127_3013796_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 443.0
HKD1_k127_3013796_3 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 412.0
HKD1_k127_3013796_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 400.0
HKD1_k127_3013796_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 387.0
HKD1_k127_3013796_6 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 321.0
HKD1_k127_3013796_7 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000000000001351 225.0
HKD1_k127_3013796_8 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000129 194.0
HKD1_k127_3013796_9 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000004271 182.0
HKD1_k127_302799_0 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 575.0
HKD1_k127_302799_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 561.0
HKD1_k127_302799_2 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 419.0
HKD1_k127_302799_3 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000007893 247.0
HKD1_k127_302799_4 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000002924 141.0
HKD1_k127_302799_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000002546 121.0
HKD1_k127_302799_6 Dodecin K09165 - - 0.00000000000000000000001876 101.0
HKD1_k127_3068767_0 Thiolase, C-terminal domain - - - 1.396e-206 647.0
HKD1_k127_3068767_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 567.0
HKD1_k127_3068767_10 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 334.0
HKD1_k127_3068767_11 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000006722 223.0
HKD1_k127_3068767_12 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000003884 213.0
HKD1_k127_3068767_13 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000001799 178.0
HKD1_k127_3068767_14 Small multidrug resistance protein K11741 - - 0.00000000000000000000000000000000000005584 145.0
HKD1_k127_3068767_15 COG0665 Glycine D-amino acid oxidases (deaminating) K19191 - 1.5.3.19 0.00000000000000000000000000006684 123.0
HKD1_k127_3068767_16 cheY-homologous receiver domain - - - 0.0000000000000000000000294 104.0
HKD1_k127_3068767_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 549.0
HKD1_k127_3068767_3 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 495.0
HKD1_k127_3068767_4 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 484.0
HKD1_k127_3068767_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 434.0
HKD1_k127_3068767_6 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 414.0
HKD1_k127_3068767_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 354.0
HKD1_k127_3068767_8 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 338.0
HKD1_k127_3068767_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 345.0
HKD1_k127_3079172_0 Adenylate and Guanylate cyclase catalytic domain - - - 4.477e-205 662.0
HKD1_k127_3079172_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 424.0
HKD1_k127_3079172_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 346.0
HKD1_k127_3079172_3 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000001699 190.0
HKD1_k127_3090194_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.055e-222 710.0
HKD1_k127_3090194_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 449.0
HKD1_k127_3090194_2 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 308.0
HKD1_k127_3090194_3 helix_turn_helix, mercury resistance K19591 - - 0.0000000000000000000000000000000000000000000003939 169.0
HKD1_k127_3090194_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.00004367 56.0
HKD1_k127_3099788_0 COG0044 Dihydroorotase and related cyclic amidohydrolases - - - 2.881e-224 704.0
HKD1_k127_3099788_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 525.0
HKD1_k127_3099788_10 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 358.0
HKD1_k127_3099788_11 AroM protein K14591 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 274.0
HKD1_k127_3099788_12 amino acid ABC transporter K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003629 273.0
HKD1_k127_3099788_13 ABC transporter permease K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000313 272.0
HKD1_k127_3099788_14 haemagglutination activity domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004551 275.0
HKD1_k127_3099788_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000317 253.0
HKD1_k127_3099788_16 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.000000000000000000000000000000000000000000000000000000000004468 216.0
HKD1_k127_3099788_17 LysM domain - - - 0.00000000000000000000000000000000006035 144.0
HKD1_k127_3099788_2 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 524.0
HKD1_k127_3099788_3 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 491.0
HKD1_k127_3099788_4 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 449.0
HKD1_k127_3099788_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 459.0
HKD1_k127_3099788_6 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 438.0
HKD1_k127_3099788_7 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 449.0
HKD1_k127_3099788_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 402.0
HKD1_k127_3099788_9 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K05712 - 1.14.13.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 370.0
HKD1_k127_3121302_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1039.0
HKD1_k127_3121302_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 602.0
HKD1_k127_3121302_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 354.0
HKD1_k127_3121302_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 347.0
HKD1_k127_3121302_4 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 320.0
HKD1_k127_3121302_5 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 323.0
HKD1_k127_3121302_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 306.0
HKD1_k127_3121302_7 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000004582 185.0
HKD1_k127_3121302_8 4,5-dihydroxyphthalate decarboxylase - - - 0.00000000000000000000000000000000000000000000006948 175.0
HKD1_k127_315771_0 FAD dependent oxidoreductase central domain - - - 0.0 1294.0
HKD1_k127_315771_1 Oligopeptide/dipeptide transporter, C-terminal region - - - 1.079e-215 683.0
HKD1_k127_315771_2 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 518.0
HKD1_k127_315771_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 470.0
HKD1_k127_315771_4 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 322.0
HKD1_k127_315771_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 314.0
HKD1_k127_315771_6 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000003959 221.0
HKD1_k127_3210685_0 DNA helicase K03657 - 3.6.4.12 6.304e-321 999.0
HKD1_k127_3210685_1 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 541.0
HKD1_k127_3210685_2 Acetyltransferase (GNAT) domain - - - 0.000000000006332 78.0
HKD1_k127_3210685_3 Protein of unknown function (DUF2817) - - - 0.00000606 50.0
HKD1_k127_3213384_0 ABC-type sugar transport system periplasmic component K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 597.0
HKD1_k127_3213384_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 517.0
HKD1_k127_3213384_10 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000001842 101.0
HKD1_k127_3213384_12 ATP-grasp domain K01955 - 6.3.5.5 0.000000000965 70.0
HKD1_k127_3213384_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 465.0
HKD1_k127_3213384_3 COG0477 Permeases of the major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 469.0
HKD1_k127_3213384_4 Binding-protein-dependent transport system inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 406.0
HKD1_k127_3213384_5 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 378.0
HKD1_k127_3213384_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 328.0
HKD1_k127_3213384_7 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005002 281.0
HKD1_k127_3213384_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000466 270.0
HKD1_k127_3213384_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000001349 237.0
HKD1_k127_3242663_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 432.0
HKD1_k127_3242663_1 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 409.0
HKD1_k127_3242663_2 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 313.0
HKD1_k127_3242663_3 DTW K05812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004649 263.0
HKD1_k127_3242663_4 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001957 250.0
HKD1_k127_3242663_5 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002748 236.0
HKD1_k127_3242663_7 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000007114 138.0
HKD1_k127_3247959_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 567.0
HKD1_k127_3247959_1 ChrR Cupin-like domain - - - 0.00000000000000002087 85.0
HKD1_k127_3247959_2 Heat shock 70 kDa protein K04043 - - 0.00000000000000006106 84.0
HKD1_k127_3251897_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.001e-221 703.0
HKD1_k127_3251897_1 PFAM major facilitator superfamily MFS_1 K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 441.0
HKD1_k127_3251897_2 PFAM amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 430.0
HKD1_k127_3251897_3 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 364.0
HKD1_k127_3251897_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 342.0
HKD1_k127_3251897_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 295.0
HKD1_k127_3251897_6 - - - - 0.0000000000000000000000000000000000000000000001066 172.0
HKD1_k127_3251897_7 YjbR - - - 0.0000000000000000000000000000000000000000007115 176.0
HKD1_k127_3304167_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2228.0
HKD1_k127_3304167_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.166e-282 876.0
HKD1_k127_3304167_2 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 587.0
HKD1_k127_3304167_3 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 500.0
HKD1_k127_3304167_4 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 477.0
HKD1_k127_3304167_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 442.0
HKD1_k127_3304167_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 416.0
HKD1_k127_3304167_7 haemagglutination activity domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 388.0
HKD1_k127_3322147_0 PrkA AAA domain K07180 GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 390.0
HKD1_k127_3322147_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 374.0
HKD1_k127_3322147_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 376.0
HKD1_k127_3323833_0 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 3.613e-278 873.0
HKD1_k127_3323833_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 8.651e-240 767.0
HKD1_k127_3323833_10 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002109 259.0
HKD1_k127_3323833_11 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001079 249.0
HKD1_k127_3323833_12 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001338 241.0
HKD1_k127_3323833_13 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000003421 203.0
HKD1_k127_3323833_14 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000006245 136.0
HKD1_k127_3323833_2 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 562.0
HKD1_k127_3323833_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 514.0
HKD1_k127_3323833_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 503.0
HKD1_k127_3323833_5 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 504.0
HKD1_k127_3323833_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 484.0
HKD1_k127_3323833_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
HKD1_k127_3323833_8 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 303.0
HKD1_k127_3323833_9 Uncharacterized protein conserved in bacteria (DUF2272) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 288.0
HKD1_k127_3349662_0 Belongs to the ABC transporter superfamily K13896 - - 2.692e-258 805.0
HKD1_k127_3349662_1 ABC-type oligopeptide transport system, periplasmic component K02035,K13893 - - 9.62e-251 799.0
HKD1_k127_3349662_10 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000002305 153.0
HKD1_k127_3349662_11 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000005288 149.0
HKD1_k127_3349662_12 Protein of unknown function (DUF3303) - - - 0.00000000000000000000000000000000003118 136.0
HKD1_k127_3349662_13 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000005205 123.0
HKD1_k127_3349662_14 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000002454 119.0
HKD1_k127_3349662_15 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0002798 45.0
HKD1_k127_3349662_2 transport system, permease component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 576.0
HKD1_k127_3349662_3 transport system, permease component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 529.0
HKD1_k127_3349662_4 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 432.0
HKD1_k127_3349662_5 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
HKD1_k127_3349662_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
HKD1_k127_3349662_7 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 350.0
HKD1_k127_3349662_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 319.0
HKD1_k127_3349662_9 COG3474 Cytochrome c2 K08738 - - 0.000000000000000000000000000000000000000000000000000003041 195.0
HKD1_k127_3352350_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 497.0
HKD1_k127_3352350_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 447.0
HKD1_k127_3352350_10 Histidine kinase-like ATPases - - - 0.0001746 44.0
HKD1_k127_3352350_2 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 358.0
HKD1_k127_3352350_3 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 332.0
HKD1_k127_3352350_4 Peptidase family S49 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006026 284.0
HKD1_k127_3352350_5 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000006758 228.0
HKD1_k127_3352350_6 Protein of unknown function (DUF459) K09795 - - 0.00000000000000000000000000000000000007598 151.0
HKD1_k127_3352350_7 - - - - 0.000000000000000000000000000000000009418 140.0
HKD1_k127_3352350_8 Putative prokaryotic signal transducing protein - - - 0.00000000000000007295 87.0
HKD1_k127_34191_0 Belongs to the UbiD family K03182 - 4.1.1.98 2.241e-275 849.0
HKD1_k127_34191_1 Zn-dependent proteases and their inactivated homologs K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 552.0
HKD1_k127_34191_2 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 529.0
HKD1_k127_34191_3 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 386.0
HKD1_k127_34191_4 amino acid ABC transporter K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 347.0
HKD1_k127_34191_5 COG0765 ABC-type amino acid transport system, permease component K02029,K09971,K10002,K10037 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005597 291.0
HKD1_k127_3474827_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.167e-243 754.0
HKD1_k127_3474827_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 547.0
HKD1_k127_3474827_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 491.0
HKD1_k127_3474827_3 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 433.0
HKD1_k127_3474827_4 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 381.0
HKD1_k127_3474827_5 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 290.0
HKD1_k127_3474827_6 transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007206 254.0
HKD1_k127_3474827_7 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000000006061 205.0
HKD1_k127_3474827_8 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000000000000008167 193.0
HKD1_k127_3513635_0 ABC-type dipeptide transport system periplasmic component K02035 - - 2.058e-220 695.0
HKD1_k127_3513635_1 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 472.0
HKD1_k127_3513635_2 COG2202 FOG PAS PAC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 399.0
HKD1_k127_3513635_3 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009425 250.0
HKD1_k127_3513635_4 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
HKD1_k127_3513635_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000001578 200.0
HKD1_k127_3513635_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000007876 59.0
HKD1_k127_3611133_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 5.027e-276 857.0
HKD1_k127_3611133_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 372.0
HKD1_k127_3611133_2 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001262 293.0
HKD1_k127_3611133_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000004642 220.0
HKD1_k127_3628658_0 Bacterial NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0 1739.0
HKD1_k127_3628658_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1185.0
HKD1_k127_3628658_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000001882 126.0
HKD1_k127_3628658_11 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000005485 115.0
HKD1_k127_3628658_12 PFAM Terminase small subunit K07474 - - 0.0000000000000000000001651 110.0
HKD1_k127_3628658_13 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000606 90.0
HKD1_k127_3628658_2 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0 1082.0
HKD1_k127_3628658_3 HsdM N-terminal domain K03427 - 2.1.1.72 3.233e-194 617.0
HKD1_k127_3628658_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 448.0
HKD1_k127_3628658_5 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 390.0
HKD1_k127_3628658_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008073 281.0
HKD1_k127_3628658_7 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001019 285.0
HKD1_k127_3628658_8 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000007766 238.0
HKD1_k127_3628658_9 - - - - 0.000000000000000000000000000000000000001453 156.0
HKD1_k127_3630098_0 ABC-type Fe3 transport system, permease component K02011 - - 5.081e-230 735.0
HKD1_k127_3630098_1 TOBE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 455.0
HKD1_k127_3630098_2 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 421.0
HKD1_k127_3630098_3 Galactose oxidase, central domain - - - 0.000000000000000003073 94.0
HKD1_k127_3630098_4 Phage integrase family - - - 0.0000000000003347 82.0
HKD1_k127_3634280_0 NADH flavin oxidoreductase NADH oxidase K21833 - - 3.629e-223 700.0
HKD1_k127_3634280_1 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 526.0
HKD1_k127_3634280_10 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
HKD1_k127_3634280_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002391 281.0
HKD1_k127_3634280_12 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000144 277.0
HKD1_k127_3634280_13 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003435 270.0
HKD1_k127_3634280_14 mandelate racemase muconate lactonizing K01856,K19802 - 5.1.1.20,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001345 259.0
HKD1_k127_3634280_15 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000004022 213.0
HKD1_k127_3634280_17 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000153 175.0
HKD1_k127_3634280_18 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000004754 154.0
HKD1_k127_3634280_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 444.0
HKD1_k127_3634280_3 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 406.0
HKD1_k127_3634280_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 400.0
HKD1_k127_3634280_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 394.0
HKD1_k127_3634280_6 Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 347.0
HKD1_k127_3634280_7 Belongs to the LDH2 MDH2 oxidoreductase family K13609 - 1.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 350.0
HKD1_k127_3634280_8 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000998 326.0
HKD1_k127_3634280_9 LysR substrate binding domain K13794,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 308.0
HKD1_k127_3649447_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.089e-218 694.0
HKD1_k127_3649447_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 548.0
HKD1_k127_3649447_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 529.0
HKD1_k127_3649447_3 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 484.0
HKD1_k127_3649447_4 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 351.0
HKD1_k127_3649447_5 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001167 249.0
HKD1_k127_3661339_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.74e-244 761.0
HKD1_k127_3661339_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 505.0
HKD1_k127_3661339_10 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003525 270.0
HKD1_k127_3661339_11 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001398 265.0
HKD1_k127_3661339_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000004246 249.0
HKD1_k127_3661339_13 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000008249 243.0
HKD1_k127_3661339_14 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
HKD1_k127_3661339_15 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
HKD1_k127_3661339_16 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000008863 222.0
HKD1_k127_3661339_17 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000001693 183.0
HKD1_k127_3661339_18 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000008337 195.0
HKD1_k127_3661339_19 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000001654 173.0
HKD1_k127_3661339_2 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 494.0
HKD1_k127_3661339_20 (Fe-S) oxidoreductase K18928 - - 0.000000000000000000000000000000000000000002626 156.0
HKD1_k127_3661339_22 PAS domain - - - 0.000000000000000000000000000000005132 142.0
HKD1_k127_3661339_23 PAS domain - - - 0.00000000000000000000000002736 123.0
HKD1_k127_3661339_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 456.0
HKD1_k127_3661339_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 456.0
HKD1_k127_3661339_5 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 466.0
HKD1_k127_3661339_6 Dihydrodipicolinate synthetase family K01714,K13876 - 4.2.1.43,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 428.0
HKD1_k127_3661339_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 399.0
HKD1_k127_3661339_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 366.0
HKD1_k127_3661339_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
HKD1_k127_366599_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1054.0
HKD1_k127_366599_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 468.0
HKD1_k127_366599_2 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 400.0
HKD1_k127_366599_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 260.0
HKD1_k127_366599_4 Alpha beta hydrolase K06889 - - 0.00000000008397 64.0
HKD1_k127_3681443_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1369.0
HKD1_k127_3681443_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 7.138e-307 949.0
HKD1_k127_3681443_10 6-pyruvoyl tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
HKD1_k127_3681443_11 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000573 205.0
HKD1_k127_3681443_12 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000424 200.0
HKD1_k127_3681443_13 Domain of unknown function (DUF3576) - - - 0.0000000000000000000000000000000000000000000001578 174.0
HKD1_k127_3681443_14 - - - - 0.0000000000000000000000000000000000009279 150.0
HKD1_k127_3681443_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000008269 117.0
HKD1_k127_3681443_16 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000000002379 76.0
HKD1_k127_3681443_17 Plasmid stabilization system K07746,K19092 - - 0.000000000001469 74.0
HKD1_k127_3681443_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 456.0
HKD1_k127_3681443_3 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 424.0
HKD1_k127_3681443_4 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 404.0
HKD1_k127_3681443_5 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 346.0
HKD1_k127_3681443_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 307.0
HKD1_k127_3681443_7 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 305.0
HKD1_k127_3681443_8 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 308.0
HKD1_k127_3681443_9 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000003147 241.0
HKD1_k127_3714117_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.89e-296 917.0
HKD1_k127_3714117_1 peptidase U62, modulator of DNA gyrase K03568 - - 3.027e-250 793.0
HKD1_k127_3714117_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 326.0
HKD1_k127_3714117_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003147 249.0
HKD1_k127_3714117_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000009088 114.0
HKD1_k127_3788135_0 Glycosyl transferases group 1 K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 321.0
HKD1_k127_3788135_1 ligase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000001584 223.0
HKD1_k127_3788135_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000007929 137.0
HKD1_k127_3788135_3 Lipopolysaccharide-assembly K03643 - - 0.00000000000000000000000000000002262 132.0
HKD1_k127_3788135_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000003554 130.0
HKD1_k127_3788135_5 DoxX K15977 - - 0.00000000000000000000007858 103.0
HKD1_k127_3788135_6 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000003104 76.0
HKD1_k127_3805675_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 462.0
HKD1_k127_3805675_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 372.0
HKD1_k127_3805675_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000001508 215.0
HKD1_k127_3805675_3 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000004911 172.0
HKD1_k127_3805675_5 phosphorelay signal transduction system - - - 0.000000000000000000332 100.0
HKD1_k127_3806137_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.432e-267 827.0
HKD1_k127_3806137_1 enoyl-CoA hydratase K15513 - 4.1.2.44 5.094e-265 828.0
HKD1_k127_3806137_2 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 449.0
HKD1_k127_3806137_3 PAS fold K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002027 282.0
HKD1_k127_3806137_4 Shikimate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008376 256.0
HKD1_k127_3812721_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1304.0
HKD1_k127_3812721_1 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 591.0
HKD1_k127_3812721_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 294.0
HKD1_k127_3812721_3 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000001558 236.0
HKD1_k127_3812721_4 Nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001456 214.0
HKD1_k127_3812721_5 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001865 211.0
HKD1_k127_3812721_6 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000004835 181.0
HKD1_k127_3812721_7 ChrR Cupin-like domain - - - 0.00000000001198 65.0
HKD1_k127_3839227_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0 1101.0
HKD1_k127_3839227_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 2.075e-294 914.0
HKD1_k127_3839227_10 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000386 112.0
HKD1_k127_3839227_2 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 7.024e-293 909.0
HKD1_k127_3839227_3 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 1.588e-225 706.0
HKD1_k127_3839227_4 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 567.0
HKD1_k127_3839227_5 transcriptional regulator, XRE family K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 423.0
HKD1_k127_3839227_6 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
HKD1_k127_3839227_7 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
HKD1_k127_3839227_8 In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 295.0
HKD1_k127_3839227_9 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 295.0
HKD1_k127_3846348_0 ABC transporter transmembrane region K02021 - - 0.0 1079.0
HKD1_k127_3846348_1 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 605.0
HKD1_k127_3846348_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 538.0
HKD1_k127_3846348_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000002023 186.0
HKD1_k127_3846348_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00008505 48.0
HKD1_k127_3883101_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 480.0
HKD1_k127_3883101_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 418.0
HKD1_k127_3883101_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004167 282.0
HKD1_k127_3883101_3 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000003638 219.0
HKD1_k127_3883101_4 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000002111 65.0
HKD1_k127_3883101_5 Radical SAM - - - 0.00006153 53.0
HKD1_k127_3945767_0 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 416.0
HKD1_k127_3945767_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 413.0
HKD1_k127_3945767_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 346.0
HKD1_k127_3945767_3 abc transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003059 277.0
HKD1_k127_3945767_4 Porin subfamily - - - 0.00000000000000000000000000000000000000000000000481 189.0
HKD1_k127_3945767_5 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000001468 130.0
HKD1_k127_3945767_6 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000006594 108.0
HKD1_k127_3970303_0 Belongs to the IlvD Edd family K13875 - 4.2.1.25 1.862e-292 908.0
HKD1_k127_3970303_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 522.0
HKD1_k127_3970303_10 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000003024 234.0
HKD1_k127_3970303_11 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000001106 225.0
HKD1_k127_3970303_12 (ABC) transporter K02065 - - 0.0000000000000000000000000000000000000000000000000003298 192.0
HKD1_k127_3970303_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000001901 151.0
HKD1_k127_3970303_14 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000001467 124.0
HKD1_k127_3970303_15 AIG2-like family - - - 0.00000000000000000000000001285 117.0
HKD1_k127_3970303_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 462.0
HKD1_k127_3970303_3 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 411.0
HKD1_k127_3970303_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 370.0
HKD1_k127_3970303_5 COG0524 Sugar kinases, ribokinase family K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 320.0
HKD1_k127_3970303_6 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 304.0
HKD1_k127_3970303_7 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000004613 274.0
HKD1_k127_3970303_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001757 286.0
HKD1_k127_3970303_9 peptidyl-lysine hydroxylation - - - 0.00000000000000000000000000000000000000000000000000000000000001549 222.0
HKD1_k127_404084_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 7.989e-241 755.0
HKD1_k127_404084_1 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 612.0
HKD1_k127_404084_2 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 540.0
HKD1_k127_404084_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 532.0
HKD1_k127_404084_4 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 295.0
HKD1_k127_404084_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000008499 219.0
HKD1_k127_404084_6 Protein of unknown function (DUF2846) - - - 0.00000009861 61.0
HKD1_k127_4078268_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 526.0
HKD1_k127_4078268_1 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
HKD1_k127_4078268_2 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000188 204.0
HKD1_k127_4078268_3 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000001648 123.0
HKD1_k127_4102934_0 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 353.0
HKD1_k127_4102934_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 325.0
HKD1_k127_4102934_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000001154 194.0
HKD1_k127_4102934_3 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000001797 129.0
HKD1_k127_4103177_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 542.0
HKD1_k127_4103177_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 490.0
HKD1_k127_4103177_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 490.0
HKD1_k127_4103177_3 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 389.0
HKD1_k127_4103177_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 360.0
HKD1_k127_4103177_5 Domain of unknown function (DUF1848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 352.0
HKD1_k127_4103177_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 330.0
HKD1_k127_4103177_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
HKD1_k127_4103177_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000001491 235.0
HKD1_k127_4103177_9 Belongs to the UPF0102 family K07460 - - 0.0000000000008124 79.0
HKD1_k127_4107352_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.405e-306 951.0
HKD1_k127_4107352_1 Protein of unknown function (DUF3376) - - - 5.357e-196 623.0
HKD1_k127_4107352_2 ATPases associated with a variety of cellular activities K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 345.0
HKD1_k127_4107352_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001075 263.0
HKD1_k127_4107352_4 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000009861 182.0
HKD1_k127_4107352_5 ABC transporter K11962 - - 0.000000000000000000000000000000000000000000000003713 181.0
HKD1_k127_4107352_6 UreE urease accessory protein, N-terminal domain K03187 - - 0.00000000000000000000000000000000000000000003902 183.0
HKD1_k127_4107352_7 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.000000000000000000000000000000000000000000116 162.0
HKD1_k127_4107352_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000002522 126.0
HKD1_k127_41273_0 MlrC C-terminus - - - 5.672e-211 666.0
HKD1_k127_41273_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 450.0
HKD1_k127_41273_10 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000002326 103.0
HKD1_k127_41273_2 belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 362.0
HKD1_k127_41273_3 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000003977 215.0
HKD1_k127_41273_4 - - - - 0.000000000000000000000000000000000000000000000000609 184.0
HKD1_k127_41273_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000006245 175.0
HKD1_k127_41273_6 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000003646 163.0
HKD1_k127_41273_7 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000006612 153.0
HKD1_k127_41273_8 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000002162 144.0
HKD1_k127_41273_9 DoxX K15977 - - 0.00000000000000000000000000000002041 140.0
HKD1_k127_4136675_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 3.372e-213 677.0
HKD1_k127_4136675_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 8.218e-213 667.0
HKD1_k127_4136675_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 336.0
HKD1_k127_4136675_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 285.0
HKD1_k127_4136675_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007836 240.0
HKD1_k127_4136675_13 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000002721 212.0
HKD1_k127_4136675_14 COG1846 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000005157 205.0
HKD1_k127_4136675_15 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000001634 188.0
HKD1_k127_4136675_16 - - - - 0.00000000000000000000000000000000000000000000000002173 191.0
HKD1_k127_4136675_17 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000001934 185.0
HKD1_k127_4136675_18 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000008194 168.0
HKD1_k127_4136675_19 EthD domain - - - 0.00000000000000000000000000000000000000001696 154.0
HKD1_k127_4136675_2 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 599.0
HKD1_k127_4136675_20 Cupin domain - - - 0.0000000000000000000000000005756 117.0
HKD1_k127_4136675_21 Thioesterase superfamily K01075 - 3.1.2.23 0.000000000000000000003302 98.0
HKD1_k127_4136675_22 - - - - 0.000000000006571 74.0
HKD1_k127_4136675_3 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 524.0
HKD1_k127_4136675_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 495.0
HKD1_k127_4136675_5 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 462.0
HKD1_k127_4136675_6 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 453.0
HKD1_k127_4136675_7 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
HKD1_k127_4136675_8 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 377.0
HKD1_k127_4136675_9 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 358.0
HKD1_k127_4145039_0 Alpha-2-Macroglobulin K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 621.0
HKD1_k127_4145039_1 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 492.0
HKD1_k127_4145039_2 protein conserved in bacteria K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 450.0
HKD1_k127_4145039_3 - - - - 0.00000000000000000003145 105.0
HKD1_k127_4180759_0 Sulfate permease family - - - 3.535e-284 899.0
HKD1_k127_4180759_1 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 596.0
HKD1_k127_4180759_2 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 467.0
HKD1_k127_4180759_3 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000004863 128.0
HKD1_k127_4182945_0 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 1.335e-245 766.0
HKD1_k127_4182945_1 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 413.0
HKD1_k127_4182945_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 320.0
HKD1_k127_4182945_3 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002422 258.0
HKD1_k127_4182945_4 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005907 252.0
HKD1_k127_4182945_5 Rieske (2fe-2S) K00479 - - 0.000000000000000000000000000000000000000000000000000000168 204.0
HKD1_k127_4182945_6 - - - - 0.0000000000000000000000000000001471 143.0
HKD1_k127_4195880_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1443.0
HKD1_k127_4195880_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18307 - - 0.0 1347.0
HKD1_k127_4195880_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 376.0
HKD1_k127_4195880_11 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003824 290.0
HKD1_k127_4195880_12 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004308 242.0
HKD1_k127_4195880_13 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.00000000000000000000000000000000000000000000000000000000000001582 223.0
HKD1_k127_4195880_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000001506 197.0
HKD1_k127_4195880_15 - - - - 0.00000000000000000000000000000000000000000000000000003607 193.0
HKD1_k127_4195880_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000318 189.0
HKD1_k127_4195880_17 - - - - 0.00000000000000000000000000008513 125.0
HKD1_k127_4195880_18 Belongs to the ompA family - - - 0.000000000000000000000000003706 121.0
HKD1_k127_4195880_19 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000001167 96.0
HKD1_k127_4195880_2 Peptidase dimerisation domain - - - 5.352e-221 693.0
HKD1_k127_4195880_20 membrane protein (DUF2306) - - - 0.000000000000000000004126 101.0
HKD1_k127_4195880_21 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000002438 76.0
HKD1_k127_4195880_22 Domain of unknown function (DUF1127) - - - 0.000000001291 61.0
HKD1_k127_4195880_3 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 1.832e-201 648.0
HKD1_k127_4195880_4 Aminotransferase class-III K01845 - 5.4.3.8 4.426e-199 629.0
HKD1_k127_4195880_5 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 554.0
HKD1_k127_4195880_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 454.0
HKD1_k127_4195880_7 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 424.0
HKD1_k127_4195880_8 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 402.0
HKD1_k127_4195880_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 379.0
HKD1_k127_4195941_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 0.0 1089.0
HKD1_k127_4195941_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.401e-223 704.0
HKD1_k127_4195941_10 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000001799 178.0
HKD1_k127_4195941_11 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000001862 142.0
HKD1_k127_4195941_12 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000124 118.0
HKD1_k127_4195941_13 ThiS family K03636 - - 0.0000000000000000000537 93.0
HKD1_k127_4195941_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 616.0
HKD1_k127_4195941_3 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 572.0
HKD1_k127_4195941_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 548.0
HKD1_k127_4195941_5 3-beta hydroxysteroid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 516.0
HKD1_k127_4195941_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 422.0
HKD1_k127_4195941_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 405.0
HKD1_k127_4195941_8 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 374.0
HKD1_k127_4195941_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 310.0
HKD1_k127_4207776_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 391.0
HKD1_k127_4207776_1 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 390.0
HKD1_k127_4207776_10 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000004224 204.0
HKD1_k127_4207776_11 acetyltransferase - - - 0.000000000000000000000000000000000000000000000004201 178.0
HKD1_k127_4207776_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000001177 171.0
HKD1_k127_4207776_13 Protein of unknown function (DUF3830) - - - 0.000000000000000000000000000000000000000005436 160.0
HKD1_k127_4207776_14 - - - - 0.000000000000000000000000000000000002259 154.0
HKD1_k127_4207776_15 Recombinase K06400 - - 0.00000000000000000000000001202 117.0
HKD1_k127_4207776_16 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.0000000000000000007956 93.0
HKD1_k127_4207776_17 ChaB K06197 - - 0.000000000000000001926 94.0
HKD1_k127_4207776_2 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 367.0
HKD1_k127_4207776_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 381.0
HKD1_k127_4207776_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 328.0
HKD1_k127_4207776_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 299.0
HKD1_k127_4207776_6 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 299.0
HKD1_k127_4207776_7 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 284.0
HKD1_k127_4207776_8 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005311 249.0
HKD1_k127_4207776_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - - 0.000000000000000000000000000000000000000000000000000000000006462 212.0
HKD1_k127_4214258_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.156e-292 905.0
HKD1_k127_4214258_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.903e-226 715.0
HKD1_k127_4214258_10 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001477 269.0
HKD1_k127_4214258_11 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000001063 212.0
HKD1_k127_4214258_12 Transcriptional regulators - - - 0.00000000000000000000000000000000001052 141.0
HKD1_k127_4214258_13 AMP-binding enzyme - - - 0.0000000000000000000000000000000001399 150.0
HKD1_k127_4214258_14 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000003211 126.0
HKD1_k127_4214258_15 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.00000000000000000000000002031 110.0
HKD1_k127_4214258_2 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 525.0
HKD1_k127_4214258_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 538.0
HKD1_k127_4214258_4 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 506.0
HKD1_k127_4214258_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 438.0
HKD1_k127_4214258_6 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 433.0
HKD1_k127_4214258_7 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 392.0
HKD1_k127_4214258_8 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 347.0
HKD1_k127_4214258_9 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 321.0
HKD1_k127_4241037_0 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 482.0
HKD1_k127_4241037_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 457.0
HKD1_k127_4241037_10 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000000000002444 195.0
HKD1_k127_4241037_11 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000000000001089 193.0
HKD1_k127_4241037_12 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000111 182.0
HKD1_k127_4241037_13 Phasin protein - - - 0.000000000000000000000000006285 115.0
HKD1_k127_4241037_14 Membrane fusogenic activity K09806 - - 0.00000000000000000000000002812 111.0
HKD1_k127_4241037_15 Bifunctional DNA primase/polymerase, N-terminal - - - 0.0000000000000000000000008896 114.0
HKD1_k127_4241037_16 methyl-accepting chemotaxis protein K03406 - - 0.0000000000001377 78.0
HKD1_k127_4241037_17 Creatinase/Prolidase N-terminal domain - - - 0.00001565 51.0
HKD1_k127_4241037_2 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 430.0
HKD1_k127_4241037_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 401.0
HKD1_k127_4241037_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 375.0
HKD1_k127_4241037_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 329.0
HKD1_k127_4241037_6 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 317.0
HKD1_k127_4241037_7 Arm DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 306.0
HKD1_k127_4241037_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 308.0
HKD1_k127_4241037_9 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001095 275.0
HKD1_k127_4247476_0 Putative zinc binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 526.0
HKD1_k127_4247476_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 396.0
HKD1_k127_4247476_10 DoxX K15977 - - 0.00000000000000000000000000165 117.0
HKD1_k127_4247476_2 CDP-glucose 4,6-dehydratase K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 373.0
HKD1_k127_4247476_3 Cephalosporin hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 321.0
HKD1_k127_4247476_4 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 288.0
HKD1_k127_4247476_5 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006707 269.0
HKD1_k127_4247476_6 NAD dependent epimerase dehydratase family K19180 - 1.1.1.339 0.00000000000000000000000000000000000000000000000000000000000003145 239.0
HKD1_k127_4247476_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000002354 202.0
HKD1_k127_4247476_8 YCII-related domain K09780 - - 0.0000000000000000000000000000002703 125.0
HKD1_k127_4247476_9 DoxX K15977 - - 0.0000000000000000000000000000009926 126.0
HKD1_k127_427237_0 Uncharacterized protein family (UPF0051) K09014 - - 3.857e-279 871.0
HKD1_k127_427237_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.989e-228 717.0
HKD1_k127_427237_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 7.491e-224 702.0
HKD1_k127_427237_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 491.0
HKD1_k127_427237_4 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 414.0
HKD1_k127_427237_5 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 392.0
HKD1_k127_427237_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 298.0
HKD1_k127_427237_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000007672 170.0
HKD1_k127_427237_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000144 87.0
HKD1_k127_4274158_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.134e-256 796.0
HKD1_k127_4274158_1 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 572.0
HKD1_k127_4274158_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 413.0
HKD1_k127_4274158_3 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 324.0
HKD1_k127_4274158_4 Threonyl and Alanyl tRNA synthetase second additional domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001353 273.0
HKD1_k127_4274158_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003124 256.0
HKD1_k127_4274158_6 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000006829 233.0
HKD1_k127_4274158_7 - - - - 0.0000000000000000000000000000000000004083 161.0
HKD1_k127_4282664_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 6.613e-199 625.0
HKD1_k127_4282664_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 396.0
HKD1_k127_4282664_10 DnaJ molecular chaperone homology domain - - - 0.00000000007233 73.0
HKD1_k127_4282664_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 397.0
HKD1_k127_4282664_3 Belongs to the heat shock protein 70 family K04045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 343.0
HKD1_k127_4282664_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 293.0
HKD1_k127_4282664_5 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009133 269.0
HKD1_k127_4282664_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000001333 242.0
HKD1_k127_4282664_7 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000005314 177.0
HKD1_k127_4282664_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000002627 108.0
HKD1_k127_4282664_9 NAD-specific glutamate dehydrogenase - - - 0.0000000000000005189 87.0
HKD1_k127_42851_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 456.0
HKD1_k127_42851_1 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 460.0
HKD1_k127_4294863_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1283.0
HKD1_k127_4294863_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 413.0
HKD1_k127_4294863_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 378.0
HKD1_k127_4294863_3 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 312.0
HKD1_k127_4294863_4 RDD family - - - 0.000000000000000000000000000004547 125.0
HKD1_k127_4294863_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000002081 59.0
HKD1_k127_4328818_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1517.0
HKD1_k127_4328818_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 7.306e-310 962.0
HKD1_k127_4328818_10 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 319.0
HKD1_k127_4328818_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 317.0
HKD1_k127_4328818_12 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000001592 271.0
HKD1_k127_4328818_13 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000000000005297 233.0
HKD1_k127_4328818_14 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000000000000000000000005637 104.0
HKD1_k127_4328818_15 COG3668 Plasmid stabilization system protein K19092 - - 0.00000000000000003545 86.0
HKD1_k127_4328818_2 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 1.389e-301 934.0
HKD1_k127_4328818_3 Molecular chaperone. Has ATPase activity K04079 - - 2.9e-268 839.0
HKD1_k127_4328818_4 Periplasmic binding protein K01999 - - 1.278e-214 675.0
HKD1_k127_4328818_5 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 523.0
HKD1_k127_4328818_6 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 456.0
HKD1_k127_4328818_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 445.0
HKD1_k127_4328818_8 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 442.0
HKD1_k127_4328818_9 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 376.0
HKD1_k127_4337333_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 481.0
HKD1_k127_4337333_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 488.0
HKD1_k127_4337333_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 468.0
HKD1_k127_4337333_3 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 461.0
HKD1_k127_434608_0 GMC oxidoreductase K00108 - 1.1.99.1 7.229e-220 695.0
HKD1_k127_434608_1 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 495.0
HKD1_k127_434608_10 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000007773 171.0
HKD1_k127_434608_11 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000002241 134.0
HKD1_k127_434608_13 Protein of unknown function (DUF1150) - - - 0.000000000000000000000005309 102.0
HKD1_k127_434608_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 433.0
HKD1_k127_434608_3 aminotransferase class I and II K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 428.0
HKD1_k127_434608_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 291.0
HKD1_k127_434608_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 285.0
HKD1_k127_434608_6 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004353 278.0
HKD1_k127_434608_7 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000000000000000000002884 213.0
HKD1_k127_434608_8 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000718 211.0
HKD1_k127_434608_9 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000007141 188.0
HKD1_k127_4363057_0 Peptidase family M20/M25/M40 - - - 1.046e-225 707.0
HKD1_k127_4363057_1 Aminotransferase class-III K15372 - 2.6.1.55 4.257e-225 705.0
HKD1_k127_4363057_2 Rieske 2Fe-2S domain protein K14748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 399.0
HKD1_k127_4363057_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 368.0
HKD1_k127_4363057_4 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 310.0
HKD1_k127_4363057_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000001047 251.0
HKD1_k127_4363057_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001374 234.0
HKD1_k127_4363057_7 Ring hydroxylating subunit beta family protein 1 - - - 0.00000000000000000000000000002824 131.0
HKD1_k127_4390958_0 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 8.061e-211 674.0
HKD1_k127_4390958_1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 408.0
HKD1_k127_4390958_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 343.0
HKD1_k127_4390958_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 306.0
HKD1_k127_4390958_4 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004652 289.0
HKD1_k127_4392828_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 547.0
HKD1_k127_4392828_1 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 309.0
HKD1_k127_4392828_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000009697 260.0
HKD1_k127_4392828_3 - - - - 0.0002243 51.0
HKD1_k127_4399057_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 4.184e-228 718.0
HKD1_k127_4399057_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 458.0
HKD1_k127_4399057_2 GcrA cell cycle regulator K13583 - - 0.0000000000000000000000000000000000000000008664 162.0
HKD1_k127_4399057_3 Plasmid stabilization K19092 - - 0.000000000000000000000000004081 113.0
HKD1_k127_4399057_5 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000005025 55.0
HKD1_k127_4399057_6 - - - - 0.0005003 45.0
HKD1_k127_4421617_0 Adenylate cyclase - - - 2.266e-208 693.0
HKD1_k127_4421617_1 Cysteine-rich domain K11473 - - 2.418e-194 616.0
HKD1_k127_4421617_2 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 482.0
HKD1_k127_4421617_3 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004584 267.0
HKD1_k127_4421617_4 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000004119 199.0
HKD1_k127_4421617_5 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000918 189.0
HKD1_k127_4421617_6 FAD binding domain K11472 - - 0.00000000000000000000000000000000000317 141.0
HKD1_k127_4421617_7 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000002497 107.0
HKD1_k127_4421617_8 PilZ domain - - - 0.00002396 53.0
HKD1_k127_4444291_0 Phosphate acyltransferases - - - 1.965e-212 691.0
HKD1_k127_4444291_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.247e-207 662.0
HKD1_k127_4444291_10 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000007013 256.0
HKD1_k127_4444291_11 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000001242 213.0
HKD1_k127_4444291_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000002749 127.0
HKD1_k127_4444291_13 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000183 78.0
HKD1_k127_4444291_15 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000008791 58.0
HKD1_k127_4444291_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 580.0
HKD1_k127_4444291_3 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 530.0
HKD1_k127_4444291_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 521.0
HKD1_k127_4444291_5 PFAM Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 347.0
HKD1_k127_4444291_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 336.0
HKD1_k127_4444291_7 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 325.0
HKD1_k127_4444291_8 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 314.0
HKD1_k127_4444291_9 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001558 269.0
HKD1_k127_4531064_0 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 1.6e-258 813.0
HKD1_k127_4531064_1 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 3.759e-221 701.0
HKD1_k127_4531064_2 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 479.0
HKD1_k127_4531064_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 283.0
HKD1_k127_4531064_4 Glycosyltransferase family 87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005428 251.0
HKD1_k127_4531064_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001662 246.0
HKD1_k127_4531064_7 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000002615 177.0
HKD1_k127_4531064_8 - - - - 0.00000000000000000000000000000000002883 139.0
HKD1_k127_4531064_9 DinB superfamily - - - 0.0000000000000000009455 93.0
HKD1_k127_4548093_0 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 6.016e-296 918.0
HKD1_k127_4548093_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 9.626e-291 898.0
HKD1_k127_4548093_10 shape-determining protein K03571 - - 0.000000000000000000000000000000000001347 147.0
HKD1_k127_4548093_11 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.00000000000000000000000000000002541 141.0
HKD1_k127_4548093_2 Rod shape-determining protein MreB K03569 - - 6.787e-197 629.0
HKD1_k127_4548093_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 595.0
HKD1_k127_4548093_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 559.0
HKD1_k127_4548093_5 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 523.0
HKD1_k127_4548093_6 Arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 381.0
HKD1_k127_4548093_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 338.0
HKD1_k127_4548093_8 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 327.0
HKD1_k127_4548093_9 Acetolactate synthase small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 284.0
HKD1_k127_4561371_0 Competence protein K02238 - - 1.458e-238 757.0
HKD1_k127_4561371_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.511e-238 744.0
HKD1_k127_4561371_10 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
HKD1_k127_4561371_11 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007854 287.0
HKD1_k127_4561371_12 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001383 252.0
HKD1_k127_4561371_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000004843 247.0
HKD1_k127_4561371_14 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000002576 208.0
HKD1_k127_4561371_15 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000004452 208.0
HKD1_k127_4561371_16 - - - - 0.00000000000000000000000000006093 123.0
HKD1_k127_4561371_17 - - - - 0.000000000000000002182 94.0
HKD1_k127_4561371_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.748e-207 655.0
HKD1_k127_4561371_3 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 547.0
HKD1_k127_4561371_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 467.0
HKD1_k127_4561371_5 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 331.0
HKD1_k127_4561371_6 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 325.0
HKD1_k127_4561371_7 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 317.0
HKD1_k127_4561371_8 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 296.0
HKD1_k127_4561371_9 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005585 286.0
HKD1_k127_456746_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.943e-269 833.0
HKD1_k127_456746_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 1.503e-253 786.0
HKD1_k127_456746_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 2.051e-204 646.0
HKD1_k127_456746_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 612.0
HKD1_k127_456746_4 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 325.0
HKD1_k127_456746_5 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000001948 264.0
HKD1_k127_456746_6 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000002916 197.0
HKD1_k127_456746_7 Protein of unknown function (DUF992) - - - 0.0000000000000000000000000000000000001129 148.0
HKD1_k127_4586191_0 MMPL family K07003 - - 4.685e-293 923.0
HKD1_k127_4586191_1 Radical SAM - - - 7.21e-265 828.0
HKD1_k127_4586191_2 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 329.0
HKD1_k127_4586191_3 Copper resistance protein D K07245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 305.0
HKD1_k127_4586191_4 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000001192 151.0
HKD1_k127_4587702_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1114.0
HKD1_k127_4587702_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006117 271.0
HKD1_k127_4587702_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000001388 231.0
HKD1_k127_4587702_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000003061 108.0
HKD1_k127_4588943_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 562.0
HKD1_k127_4588943_1 Sir2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 418.0
HKD1_k127_460055_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.465e-226 709.0
HKD1_k127_460055_1 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 430.0
HKD1_k127_460055_10 - - - - 0.000000007321 68.0
HKD1_k127_460055_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 375.0
HKD1_k127_460055_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 357.0
HKD1_k127_460055_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 321.0
HKD1_k127_460055_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001933 273.0
HKD1_k127_460055_6 Glycosyl-transferase family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001421 279.0
HKD1_k127_460055_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000001518 204.0
HKD1_k127_460055_8 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000001256 150.0
HKD1_k127_460055_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000005223 145.0
HKD1_k127_4609899_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 3.02e-222 693.0
HKD1_k127_4609899_1 HlyD family secretion protein K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 441.0
HKD1_k127_4609899_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000006363 104.0
HKD1_k127_4609899_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000006154 89.0
HKD1_k127_4626187_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1730.0
HKD1_k127_4626187_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000005311 143.0
HKD1_k127_4641190_0 Adenylate K01768 - 4.6.1.1 7.747e-243 769.0
HKD1_k127_4641190_1 FAD dependent oxidoreductase central domain K00315 - 1.5.8.4 1.268e-240 748.0
HKD1_k127_4641759_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 6.799e-236 736.0
HKD1_k127_4641759_1 5-aminolevulinic acid synthase K00643 - 2.3.1.37 1.137e-199 629.0
HKD1_k127_4641759_10 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 307.0
HKD1_k127_4641759_11 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 292.0
HKD1_k127_4641759_12 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 284.0
HKD1_k127_4641759_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000954 273.0
HKD1_k127_4641759_14 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004145 266.0
HKD1_k127_4641759_15 Putative AphA-like transcriptional regulator - - - 0.000000000000000000000000000000000000000000002511 171.0
HKD1_k127_4641759_16 amidohydrolase - - - 0.000000000000000000000000000000000000000000549 182.0
HKD1_k127_4641759_17 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000001514 138.0
HKD1_k127_4641759_18 Glycine-zipper domain - - - 0.0000000000000000000000000000006032 134.0
HKD1_k127_4641759_19 - - - - 0.000000000000000000000002702 117.0
HKD1_k127_4641759_2 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 599.0
HKD1_k127_4641759_20 - - - - 0.000000000000001577 83.0
HKD1_k127_4641759_21 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000001312 62.0
HKD1_k127_4641759_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 577.0
HKD1_k127_4641759_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 467.0
HKD1_k127_4641759_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 390.0
HKD1_k127_4641759_6 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 377.0
HKD1_k127_4641759_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 377.0
HKD1_k127_4641759_8 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 373.0
HKD1_k127_4641759_9 Molecular chaperone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 347.0
HKD1_k127_4660858_0 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K02230 - 6.6.1.2 0.0 1721.0
HKD1_k127_4660858_1 Cobalamin synthesis protein cobW C-terminal domain K02234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 483.0
HKD1_k127_4660858_2 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000001539 263.0
HKD1_k127_4660858_3 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000000002385 208.0
HKD1_k127_4660858_4 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000004512 201.0
HKD1_k127_4663168_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 9.005e-306 952.0
HKD1_k127_4663168_1 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 483.0
HKD1_k127_4663168_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 469.0
HKD1_k127_4663168_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 426.0
HKD1_k127_4663168_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001862 251.0
HKD1_k127_4663168_5 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000001534 182.0
HKD1_k127_4663168_6 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.0000000000000000000000000000000000000000101 156.0
HKD1_k127_4663168_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000008594 88.0
HKD1_k127_4663168_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000004696 64.0
HKD1_k127_4672923_0 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 353.0
HKD1_k127_4672923_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000002943 201.0
HKD1_k127_4672923_2 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000003999 149.0
HKD1_k127_4672923_3 COG2200 FOG EAL domain - - - 0.00000000000000000000000002747 121.0
HKD1_k127_4675143_0 FAD binding domain K00480 - 1.14.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 511.0
HKD1_k127_4675143_1 Ferritin-like K20087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 505.0
HKD1_k127_4675143_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 362.0
HKD1_k127_4675143_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 350.0
HKD1_k127_4675143_4 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000162 230.0
HKD1_k127_4675143_5 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003651 224.0
HKD1_k127_4675143_6 serine-type endopeptidase activity K08372 - - 0.0000000000000000000000000000000000000000000000000000000000005663 227.0
HKD1_k127_4675143_7 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000818 175.0
HKD1_k127_4675143_8 MAPEG family - - - 0.00000000000000000000000000000000000000002825 156.0
HKD1_k127_4676013_0 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000008054 233.0
HKD1_k127_4676013_1 Ras of Complex, Roc, domain of DAPkinase - - - 0.0000000000000000000000000007302 116.0
HKD1_k127_4676013_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000002771 59.0
HKD1_k127_469212_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3e-323 992.0
HKD1_k127_469212_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 3.204e-247 768.0
HKD1_k127_469212_10 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 469.0
HKD1_k127_469212_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 466.0
HKD1_k127_469212_12 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 443.0
HKD1_k127_469212_13 Enoyl-CoA hydratase isomerase K16880 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 329.0
HKD1_k127_469212_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 296.0
HKD1_k127_469212_15 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001146 284.0
HKD1_k127_469212_16 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004299 236.0
HKD1_k127_469212_17 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000000000000000000000000000002142 244.0
HKD1_k127_469212_18 KR domain - - - 0.00000000000000000000000000000000000000000000000000002665 210.0
HKD1_k127_469212_19 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000002909 156.0
HKD1_k127_469212_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.221e-213 694.0
HKD1_k127_469212_20 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000001046 120.0
HKD1_k127_469212_21 SnoaL-like domain - - - 0.0000000000000000000000000001346 122.0
HKD1_k127_469212_22 Septum formation initiator - - - 0.0000000000000000000000000665 110.0
HKD1_k127_469212_23 COG0457 FOG TPR repeat - - - 0.00006316 52.0
HKD1_k127_469212_24 transport system periplasmic component K01989 - - 0.0001187 48.0
HKD1_k127_469212_25 Belongs to the ClpX chaperone family - - - 0.0003129 47.0
HKD1_k127_469212_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.984e-203 659.0
HKD1_k127_469212_4 Belongs to the thiolase family K00626 - 2.3.1.9 5.066e-201 634.0
HKD1_k127_469212_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 3.718e-194 614.0
HKD1_k127_469212_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 528.0
HKD1_k127_469212_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 529.0
HKD1_k127_469212_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 482.0
HKD1_k127_469212_9 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 490.0
HKD1_k127_4695161_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.803e-256 801.0
HKD1_k127_4695161_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 484.0
HKD1_k127_4695161_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000191 189.0
HKD1_k127_4712334_0 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 557.0
HKD1_k127_4712334_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 443.0
HKD1_k127_4712334_2 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 370.0
HKD1_k127_4712334_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 353.0
HKD1_k127_4712334_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004038 236.0
HKD1_k127_4712334_5 - - - - 0.0000000000000000000000000000000000000000000000000001249 197.0
HKD1_k127_4712334_6 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000002362 123.0
HKD1_k127_4757177_0 DNA polymerase X family K02347 - - 7.601e-237 751.0
HKD1_k127_4757177_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.201e-219 688.0
HKD1_k127_4757177_10 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004038 226.0
HKD1_k127_4757177_11 Domain of unknown function (DUF1287) K09974 - - 0.000000000000000000000000000000000000000000000000000000000000003065 227.0
HKD1_k127_4757177_12 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000001162 183.0
HKD1_k127_4757177_13 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000001469 166.0
HKD1_k127_4757177_14 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000001161 149.0
HKD1_k127_4757177_15 Aspartyl protease K06985 - - 0.00000000000000000000000003249 114.0
HKD1_k127_4757177_16 Protein of unknown function (DUF3775) - - - 0.00000000003637 68.0
HKD1_k127_4757177_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 521.0
HKD1_k127_4757177_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 484.0
HKD1_k127_4757177_4 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 421.0
HKD1_k127_4757177_5 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 361.0
HKD1_k127_4757177_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008157 296.0
HKD1_k127_4757177_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009516 272.0
HKD1_k127_4757177_8 3-beta hydroxysteroid dehydrogenase/isomerase family K18981 - 1.1.1.203 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001808 276.0
HKD1_k127_4757177_9 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002239 281.0
HKD1_k127_4789920_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.774e-245 760.0
HKD1_k127_4789920_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 585.0
HKD1_k127_4789920_10 membrane - - - 0.00000000000000000000000000159 116.0
HKD1_k127_4789920_11 Domain of unknown function (DUF4282) - - - 0.000000000000006708 79.0
HKD1_k127_4789920_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 545.0
HKD1_k127_4789920_3 CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 449.0
HKD1_k127_4789920_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 415.0
HKD1_k127_4789920_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 345.0
HKD1_k127_4789920_6 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 310.0
HKD1_k127_4789920_7 Belongs to the pyridoxine kinase family K00868 - 2.7.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 316.0
HKD1_k127_4789920_8 Protein of unknown function (DUF2852) - - - 0.000000000000000000000000000000000000000001103 160.0
HKD1_k127_4789920_9 Domain of unknown function (DUF4410) - - - 0.00000000000000000000000000000000000000001585 160.0
HKD1_k127_4794961_0 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 512.0
HKD1_k127_4794961_1 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 485.0
HKD1_k127_4794961_2 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 439.0
HKD1_k127_4794961_3 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 372.0
HKD1_k127_4818680_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1976.0
HKD1_k127_4818680_1 aminopeptidase K01262 - 3.4.11.9 3.888e-195 614.0
HKD1_k127_4818680_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 353.0
HKD1_k127_4818680_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 331.0
HKD1_k127_4818680_4 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000003211 212.0
HKD1_k127_4826539_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.571e-218 687.0
HKD1_k127_4826539_1 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 7.301e-205 642.0
HKD1_k127_4826539_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000008914 94.0
HKD1_k127_4826539_11 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.000000003026 61.0
HKD1_k127_4826539_2 succinylglutamate desuccinylase aspartoacylase K06987,K15784 - 3.5.1.125 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 509.0
HKD1_k127_4826539_3 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 473.0
HKD1_k127_4826539_4 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 422.0
HKD1_k127_4826539_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 377.0
HKD1_k127_4826539_6 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 349.0
HKD1_k127_4826539_7 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000004123 235.0
HKD1_k127_4826539_8 response regulator - - - 0.0000000000000000000000000000000000004772 157.0
HKD1_k127_4826539_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000001311 112.0
HKD1_k127_483515_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1761.0
HKD1_k127_483515_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.265e-220 700.0
HKD1_k127_483515_2 Belongs to the CarA family K01956 - 6.3.5.5 6.016e-194 612.0
HKD1_k127_483515_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 608.0
HKD1_k127_483515_4 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 368.0
HKD1_k127_483515_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
HKD1_k127_483515_6 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
HKD1_k127_483515_7 Acid phosphatase homologues K12978 - - 0.000000000000000000000000000000000000000000000000000000000003051 220.0
HKD1_k127_483515_8 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000001396 198.0
HKD1_k127_483515_9 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000001047 176.0
HKD1_k127_4835188_0 AIR synthase related protein, C-terminal domain - - - 2.531e-207 675.0
HKD1_k127_4835188_1 RND efflux system, outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 548.0
HKD1_k127_4835188_2 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 371.0
HKD1_k127_4835188_3 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000001508 201.0
HKD1_k127_4835188_4 AcrB/AcrD/AcrF family K07789 - - 0.00000000000000000000000000000000000000000000000131 175.0
HKD1_k127_4835188_5 - - - - 0.000000000000000000000000000000000000000000008736 168.0
HKD1_k127_4835188_6 Glycine cleavage H-protein K02437 - - 0.0000000000000000000000000000000000000000001174 172.0
HKD1_k127_4835188_7 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000004219 162.0
HKD1_k127_4846687_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.532e-319 987.0
HKD1_k127_4846687_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 6.638e-290 907.0
HKD1_k127_4846687_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000002338 223.0
HKD1_k127_4846687_11 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000008798 186.0
HKD1_k127_4846687_12 Ubiquinol-cytochrome C chaperone K17662 - - 0.0000000000000000000000000000000000000000000002583 177.0
HKD1_k127_4846687_13 transcriptional regulator, MerR - - - 0.00000000000000000000000000000000000000000002732 165.0
HKD1_k127_4846687_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000001651 155.0
HKD1_k127_4846687_15 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000009934 155.0
HKD1_k127_4846687_16 COG2913 Small protein A (tmRNA-binding) - - - 0.000000000000000000000000000000000001012 146.0
HKD1_k127_4846687_17 - - - - 0.0000000000000000000000000000000002139 134.0
HKD1_k127_4846687_18 Protein of unknown function (DUF1348) - - - 0.0000000000000000000000000001046 120.0
HKD1_k127_4846687_19 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000004898 102.0
HKD1_k127_4846687_2 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 6.338e-234 728.0
HKD1_k127_4846687_20 - - - - 0.00000000000000000000001459 106.0
HKD1_k127_4846687_21 Uncharacterized ACR, COG1399 - - - 0.00000000000000000000002532 107.0
HKD1_k127_4846687_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000001196 85.0
HKD1_k127_4846687_23 peptidyl-tyrosine sulfation - - - 0.000001737 56.0
HKD1_k127_4846687_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 508.0
HKD1_k127_4846687_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 499.0
HKD1_k127_4846687_5 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 497.0
HKD1_k127_4846687_6 aminotransferase class I and II K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 488.0
HKD1_k127_4846687_7 Pyridoxal-dependent decarboxylase conserved domain K01593,K13745 - 4.1.1.105,4.1.1.28,4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 478.0
HKD1_k127_4846687_8 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 394.0
HKD1_k127_4846687_9 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002181 275.0
HKD1_k127_4872581_0 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 484.0
HKD1_k127_4872581_1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 414.0
HKD1_k127_4872581_2 flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 370.0
HKD1_k127_4872581_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 305.0
HKD1_k127_4872581_4 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000007128 186.0
HKD1_k127_4872581_5 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000001069 180.0
HKD1_k127_4872581_6 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000146 137.0
HKD1_k127_4872581_7 Protein of unknown function (DUF1465) K13592 - - 0.000000000000000000000000000000008552 131.0
HKD1_k127_4872581_8 COG2885 outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.0000000000000000000008412 108.0
HKD1_k127_4876868_0 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 9.588e-244 758.0
HKD1_k127_4876868_1 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 494.0
HKD1_k127_4876868_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 400.0
HKD1_k127_4876868_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 369.0
HKD1_k127_4876868_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 361.0
HKD1_k127_4876868_5 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 310.0
HKD1_k127_4876868_6 branched-chain amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 304.0
HKD1_k127_4876868_7 GntR family K03710 - - 0.00000000000000000003809 92.0
HKD1_k127_4876868_8 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 0.0000000001375 61.0
HKD1_k127_4912745_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.786e-213 689.0
HKD1_k127_4912745_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 398.0
HKD1_k127_4912745_2 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 327.0
HKD1_k127_4912745_3 Domain of unknown function (DUF1476) - - - 0.0000000000000000000000000002308 119.0
HKD1_k127_4926648_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1498.0
HKD1_k127_4926648_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 519.0
HKD1_k127_4926648_2 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 469.0
HKD1_k127_4926648_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 325.0
HKD1_k127_4926648_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000586 225.0
HKD1_k127_494790_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.032e-313 964.0
HKD1_k127_494790_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 2.722e-220 690.0
HKD1_k127_494790_10 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 338.0
HKD1_k127_494790_11 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 311.0
HKD1_k127_494790_12 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002203 234.0
HKD1_k127_494790_13 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.00000000000000000000000000000000000000000000000000001056 205.0
HKD1_k127_494790_14 Stringent starvation protein B K09985 - - 0.0000000000000000000000000000000000000000000000001343 183.0
HKD1_k127_494790_15 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000008079 165.0
HKD1_k127_494790_16 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000004356 68.0
HKD1_k127_494790_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 2.21e-206 656.0
HKD1_k127_494790_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 581.0
HKD1_k127_494790_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 575.0
HKD1_k127_494790_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 469.0
HKD1_k127_494790_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 389.0
HKD1_k127_494790_7 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
HKD1_k127_494790_8 Zinc-binding dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 362.0
HKD1_k127_494790_9 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 348.0
HKD1_k127_4965793_0 ABC transporter, substrate-binding protein, family 5 K02035 - - 6.924e-219 686.0
HKD1_k127_4965793_1 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 491.0
HKD1_k127_4965793_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 475.0
HKD1_k127_4965793_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 468.0
HKD1_k127_4965793_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 460.0
HKD1_k127_4965793_5 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 385.0
HKD1_k127_4965793_6 Putative transposase of IS4/5 family (DUF4096) K07492 - - 0.000000213 53.0
HKD1_k127_4990906_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1362.0
HKD1_k127_4990906_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1090.0
HKD1_k127_4990906_10 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 301.0
HKD1_k127_4990906_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001058 257.0
HKD1_k127_4990906_12 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001168 249.0
HKD1_k127_4990906_13 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000003331 249.0
HKD1_k127_4990906_14 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000005804 234.0
HKD1_k127_4990906_15 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000008788 224.0
HKD1_k127_4990906_16 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000000000001186 198.0
HKD1_k127_4990906_17 Glycosyl transferase, family 2 K01002 - 2.7.8.20 0.00000000000000000000000000000000000000000000000000000005239 220.0
HKD1_k127_4990906_18 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000004727 177.0
HKD1_k127_4990906_19 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000004341 162.0
HKD1_k127_4990906_2 Amidohydrolase family - - - 4.649e-225 709.0
HKD1_k127_4990906_20 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000001715 145.0
HKD1_k127_4990906_21 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000006384 109.0
HKD1_k127_4990906_22 Phasin protein - - - 0.0000003356 59.0
HKD1_k127_4990906_3 phosphomannomutase K01840 - 5.4.2.8 7.005e-225 704.0
HKD1_k127_4990906_4 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 470.0
HKD1_k127_4990906_5 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 439.0
HKD1_k127_4990906_6 Protein conserved in bacteria K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 408.0
HKD1_k127_4990906_7 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 403.0
HKD1_k127_4990906_8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 402.0
HKD1_k127_4990906_9 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 311.0
HKD1_k127_5011366_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.155e-204 647.0
HKD1_k127_5011366_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 529.0
HKD1_k127_5011366_2 Precorrin-6Y C5,15-methyltransferase K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 491.0
HKD1_k127_5011366_3 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 437.0
HKD1_k127_5011366_4 CbiX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 421.0
HKD1_k127_5011366_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 355.0
HKD1_k127_5011366_6 Precorrin-2 K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000006782 258.0
HKD1_k127_5011366_7 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000008253 197.0
HKD1_k127_5011366_8 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000001309 148.0
HKD1_k127_5011366_9 Precorrin-3B K05934,K13541 - 2.1.1.131,3.7.1.12 0.000000000000000000000000000000000004042 149.0
HKD1_k127_501241_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 466.0
HKD1_k127_501241_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 467.0
HKD1_k127_501241_10 amine dehydrogenase activity - - - 0.0000000696 59.0
HKD1_k127_501241_11 HELICc2 K03722 - 3.6.4.12 0.0000002636 57.0
HKD1_k127_501241_2 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 441.0
HKD1_k127_501241_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 395.0
HKD1_k127_501241_4 sugar phosphatases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 376.0
HKD1_k127_501241_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 383.0
HKD1_k127_501241_6 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001136 270.0
HKD1_k127_501241_7 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003145 243.0
HKD1_k127_501241_8 Protein of unknown function (DUF952) - - - 0.0000000000000000000000000000000000000000000003564 169.0
HKD1_k127_501241_9 - - - - 0.000000000000000000000000000000000000000001083 162.0
HKD1_k127_5018813_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1272.0
HKD1_k127_5018813_1 Copper resistance protein D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 572.0
HKD1_k127_5018813_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 338.0
HKD1_k127_5018813_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 337.0
HKD1_k127_5018813_12 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 314.0
HKD1_k127_5018813_13 ATPases associated with a variety of cellular activities K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 303.0
HKD1_k127_5018813_14 Succinylglutamate desuccinylase / Aspartoacylase family K15784 - 3.5.1.125 0.00000000000000000000000000000000000000000000000000000000000004164 241.0
HKD1_k127_5018813_15 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000000000002188 203.0
HKD1_k127_5018813_16 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.000000000000000000000000000000000000000000003764 167.0
HKD1_k127_5018813_17 CopC domain - - - 0.0000000000000000000000000005669 117.0
HKD1_k127_5018813_2 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 491.0
HKD1_k127_5018813_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 469.0
HKD1_k127_5018813_4 Iron-containing alcohol dehydrogenase K00043,K13954 - 1.1.1.1,1.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 410.0
HKD1_k127_5018813_5 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 406.0
HKD1_k127_5018813_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 379.0
HKD1_k127_5018813_7 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 379.0
HKD1_k127_5018813_8 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 349.0
HKD1_k127_5018813_9 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 354.0
HKD1_k127_5031928_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 355.0
HKD1_k127_5031928_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005452 252.0
HKD1_k127_5031928_2 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004242 246.0
HKD1_k127_5031928_3 Peptidase S24-like - - - 0.00000000000000000000000000000000000000000004172 171.0
HKD1_k127_5031928_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000006185 147.0
HKD1_k127_5031928_5 - - - - 0.000000000000000000000000000000000005574 146.0
HKD1_k127_5080072_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1225.0
HKD1_k127_5080072_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 1.142e-257 826.0
HKD1_k127_5080072_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 491.0
HKD1_k127_5080072_3 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 391.0
HKD1_k127_5080072_4 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 334.0
HKD1_k127_5080072_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000001444 224.0
HKD1_k127_5080072_6 transduction histidine kinase K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001948 224.0
HKD1_k127_5080072_7 SOS response K14160 - - 0.0000000000000000000000000000000000000000000003765 177.0
HKD1_k127_5080072_8 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000001059 165.0
HKD1_k127_5080072_9 Ca2 -binding protein (EF-Hand superfamily - - - 0.0000001394 63.0
HKD1_k127_5136585_0 COG1042 Acyl-CoA synthetase (NDP forming) - - - 7.275e-208 665.0
HKD1_k127_5136585_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 547.0
HKD1_k127_5136585_10 Phenylacetic acid catabolic protein - - - 0.000000000009657 66.0
HKD1_k127_5136585_2 COG0708 Exonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 422.0
HKD1_k127_5136585_3 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 405.0
HKD1_k127_5136585_4 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 392.0
HKD1_k127_5136585_5 S-adenosyl-L-methionine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004933 222.0
HKD1_k127_5136585_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000005183 199.0
HKD1_k127_5136585_7 - - - - 0.00000000000000000000000000000000000001451 164.0
HKD1_k127_5136585_8 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000000000000000000005536 98.0
HKD1_k127_5136585_9 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.00000000000000001708 88.0
HKD1_k127_5137584_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 3.594e-206 651.0
HKD1_k127_5137584_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 430.0
HKD1_k127_5137584_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 385.0
HKD1_k127_5137584_3 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 354.0
HKD1_k127_5137584_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 321.0
HKD1_k127_5137584_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000006826 154.0
HKD1_k127_5137584_6 lyase activity - - - 0.0000000000000000000000000000000000002286 153.0
HKD1_k127_5137584_7 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000002365 94.0
HKD1_k127_5147826_0 Adenylate cyclase - - - 4.575e-203 647.0
HKD1_k127_5147826_1 Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose K06163 - 4.7.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 459.0
HKD1_k127_5147826_10 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000002544 193.0
HKD1_k127_5147826_11 transporter component K07112 - - 0.00000000000000000000000000000000000000000000000003261 183.0
HKD1_k127_5147826_12 - - - - 0.000000000000000000000000000000000000000000000001172 177.0
HKD1_k127_5147826_13 Phosphonate K06164 GO:0003674,GO:0003824,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061693,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1904176,GO:1990234 2.7.8.37 0.0000000000000000000000000000000000000000000000528 183.0
HKD1_k127_5147826_14 transporter component K07112 - - 0.0000000000000000000000000000000000000000001582 164.0
HKD1_k127_5147826_15 Bacterial phosphonate metabolism protein (PhnH) K06165 - 2.7.8.37 0.0000000000000000000000000000000000003057 154.0
HKD1_k127_5147826_16 Phosphonate metabolism protein PhnG K06166 - 2.7.8.37 0.0000000000000000000000000000000000004155 145.0
HKD1_k127_5147826_17 Lytic murein transglycosylase K08305 - - 0.000002353 55.0
HKD1_k127_5147826_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 452.0
HKD1_k127_5147826_3 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 436.0
HKD1_k127_5147826_4 ATPases associated with a variety of cellular activities K05781 GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0071704,GO:1901575,GO:1902494,GO:1904176 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 363.0
HKD1_k127_5147826_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 327.0
HKD1_k127_5147826_6 phosphonate metabolism K06164 - 2.7.8.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 301.0
HKD1_k127_5147826_7 metal-dependent hydrolase involved in phosphonate metabolism K06162 - 3.6.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001395 292.0
HKD1_k127_5147826_8 (ABC transporter), ATP-binding K05780 - 2.7.8.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008521 287.0
HKD1_k127_5147826_9 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000001283 246.0
HKD1_k127_5180367_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 1.724e-211 672.0
HKD1_k127_5180367_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 524.0
HKD1_k127_5180367_10 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000004838 212.0
HKD1_k127_5180367_11 NIPSNAP - - - 0.0000000000000000000000004255 121.0
HKD1_k127_5180367_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 398.0
HKD1_k127_5180367_3 SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 395.0
HKD1_k127_5180367_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 374.0
HKD1_k127_5180367_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 366.0
HKD1_k127_5180367_6 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 372.0
HKD1_k127_5180367_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 342.0
HKD1_k127_5180367_8 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 336.0
HKD1_k127_5180367_9 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007044 256.0
HKD1_k127_5199738_0 MMPL family - - - 0.0 1633.0
HKD1_k127_5199738_1 Protein of unknown function (DUF3141) - - - 1.268e-289 910.0
HKD1_k127_5199738_10 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 344.0
HKD1_k127_5199738_11 Coenzyme A transferase K01034 - 2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 323.0
HKD1_k127_5199738_12 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 316.0
HKD1_k127_5199738_13 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001132 275.0
HKD1_k127_5199738_14 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003517 283.0
HKD1_k127_5199738_15 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001938 248.0
HKD1_k127_5199738_16 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001125 239.0
HKD1_k127_5199738_17 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
HKD1_k127_5199738_18 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000002407 209.0
HKD1_k127_5199738_19 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000001365 211.0
HKD1_k127_5199738_2 Phosphate acetyl/butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 589.0
HKD1_k127_5199738_20 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000001393 168.0
HKD1_k127_5199738_21 VIT family - - - 0.00000000000000000000000000000000004129 142.0
HKD1_k127_5199738_22 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000007097 145.0
HKD1_k127_5199738_23 IMP dehydrogenase activity - - - 0.00000000000000000000000000000002004 132.0
HKD1_k127_5199738_24 Phospholipid methyltransferase - - - 0.0000000000001658 79.0
HKD1_k127_5199738_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 475.0
HKD1_k127_5199738_4 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 456.0
HKD1_k127_5199738_5 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 441.0
HKD1_k127_5199738_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 435.0
HKD1_k127_5199738_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 400.0
HKD1_k127_5199738_8 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 390.0
HKD1_k127_5199738_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 356.0
HKD1_k127_5201256_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.171e-248 779.0
HKD1_k127_5201256_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.171e-239 764.0
HKD1_k127_5201256_10 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000000000000000000000000002834 147.0
HKD1_k127_5201256_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000002337 130.0
HKD1_k127_5201256_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 620.0
HKD1_k127_5201256_3 III protein, CoA-transferase family K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 581.0
HKD1_k127_5201256_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 511.0
HKD1_k127_5201256_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 506.0
HKD1_k127_5201256_6 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 416.0
HKD1_k127_5201256_7 Arginase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 364.0
HKD1_k127_5201256_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000001384 243.0
HKD1_k127_5201256_9 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000005711 194.0
HKD1_k127_5204135_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 587.0
HKD1_k127_5204135_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 404.0
HKD1_k127_5204135_10 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000000007885 124.0
HKD1_k127_5204135_11 Thioesterase superfamily - - - 0.000000000000000000000000004263 124.0
HKD1_k127_5204135_2 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 399.0
HKD1_k127_5204135_3 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 336.0
HKD1_k127_5204135_4 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 305.0
HKD1_k127_5204135_5 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000009893 230.0
HKD1_k127_5204135_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000003961 175.0
HKD1_k127_5204135_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000002208 157.0
HKD1_k127_5204135_8 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000000007616 145.0
HKD1_k127_5204135_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000001086 130.0
HKD1_k127_5217542_0 ATPase with chaperone activity K07391 - - 1.963e-257 801.0
HKD1_k127_5217542_1 histidine ammonia-lyase K01745 GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 8.693e-205 648.0
HKD1_k127_5217542_10 DNA-dependent DNA replication K02315 - - 0.0000000000000000000001883 110.0
HKD1_k127_5217542_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 1.495e-194 613.0
HKD1_k127_5217542_3 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 626.0
HKD1_k127_5217542_4 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 568.0
HKD1_k127_5217542_5 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 452.0
HKD1_k127_5217542_6 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008896 256.0
HKD1_k127_5217542_7 of the double-stranded beta helix - - - 0.0000000000000000000000000000000000000000000000000000000007445 207.0
HKD1_k127_5217542_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000000000000000000000000000000000000003095 164.0
HKD1_k127_5217542_9 Glycosyl transferases group 1 - - - 0.000000000000000000000005848 115.0
HKD1_k127_527804_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.161e-308 971.0
HKD1_k127_527804_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.118e-280 866.0
HKD1_k127_527804_10 Type II secretion system (T2SS), protein G - - - 0.0000000000000000000000000000000000000003639 156.0
HKD1_k127_527804_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000007906 167.0
HKD1_k127_527804_13 response to hydrogen peroxide - - - 0.0003445 50.0
HKD1_k127_527804_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.607e-279 872.0
HKD1_k127_527804_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 428.0
HKD1_k127_527804_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 372.0
HKD1_k127_527804_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 364.0
HKD1_k127_527804_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 330.0
HKD1_k127_527804_7 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004862 250.0
HKD1_k127_527804_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001068 247.0
HKD1_k127_527804_9 Suppressor of fused protein (SUFU) - - - 0.0000000000000000000000000000000000000000000000000000007857 200.0
HKD1_k127_5328903_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 1.861e-308 988.0
HKD1_k127_5328903_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 2.104e-262 825.0
HKD1_k127_5328903_10 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000001816 239.0
HKD1_k127_5328903_11 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000003107 197.0
HKD1_k127_5328903_12 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000007198 184.0
HKD1_k127_5328903_13 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000006451 181.0
HKD1_k127_5328903_14 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000005066 168.0
HKD1_k127_5328903_15 Haem-degrading - - - 0.00000000000000000000000000000000000000197 153.0
HKD1_k127_5328903_16 Transglycosylase associated protein - - - 0.00000000000000000000003748 101.0
HKD1_k127_5328903_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.931e-233 726.0
HKD1_k127_5328903_3 Adenylate cyclase - - - 6.549e-197 630.0
HKD1_k127_5328903_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 481.0
HKD1_k127_5328903_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 469.0
HKD1_k127_5328903_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
HKD1_k127_5328903_7 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 379.0
HKD1_k127_5328903_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 372.0
HKD1_k127_5328903_9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005306 270.0
HKD1_k127_5329695_0 glutamine synthetase K01915 - 6.3.1.2 1.036e-203 639.0
HKD1_k127_5329695_1 Aminotransferase class I and II - - - 1.229e-198 626.0
HKD1_k127_5329695_2 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 545.0
HKD1_k127_5329695_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 - 2.5.1.31,2.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 325.0
HKD1_k127_5329695_4 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000004961 107.0
HKD1_k127_5329695_5 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000004356 102.0
HKD1_k127_5329695_6 Peptidase propeptide and YPEB domain - - - 0.000000000000004966 86.0
HKD1_k127_5346453_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1264.0
HKD1_k127_5346453_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 317.0
HKD1_k127_5355579_0 glutamate--cysteine ligase K01919 - 6.3.2.2 3.362e-228 713.0
HKD1_k127_5355579_1 Beta-agarase K01219 - 3.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 520.0
HKD1_k127_5355579_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 436.0
HKD1_k127_5355579_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 286.0
HKD1_k127_5355579_4 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002424 289.0
HKD1_k127_5355579_5 response to heat K03668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002175 268.0
HKD1_k127_5355579_6 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001857 246.0
HKD1_k127_5355579_7 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000002457 235.0
HKD1_k127_5355579_8 PFAM Glutathione-dependent formaldehyde-activating, GFA - - - 0.00000000000000000000000000000000000000002043 161.0
HKD1_k127_5355579_9 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000002063 146.0
HKD1_k127_536040_0 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 514.0
HKD1_k127_536040_1 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 408.0
HKD1_k127_536040_2 COG0784 FOG CheY-like receiver K11443 - - 0.0000000000000000000000000000000000000000000000000000000000000000002024 231.0
HKD1_k127_536040_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00000000000000000001597 101.0
HKD1_k127_537290_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0 1240.0
HKD1_k127_537290_1 ABC transporter transmembrane region K06147 - - 2.406e-251 839.0
HKD1_k127_537290_10 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 490.0
HKD1_k127_537290_11 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 448.0
HKD1_k127_537290_12 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001989 282.0
HKD1_k127_537290_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001436 276.0
HKD1_k127_537290_14 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003728 246.0
HKD1_k127_537290_15 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 248.0
HKD1_k127_537290_16 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003447 235.0
HKD1_k127_537290_17 COQ9 K18587 - - 0.0000000000000000000000000000000000000000000000000000000000001111 228.0
HKD1_k127_537290_18 Competence-damaged protein - - - 0.000000000000000000000000000000000000000000000000000000009476 204.0
HKD1_k127_537290_19 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000027 185.0
HKD1_k127_537290_2 Radical SAM superfamily - - - 7.427e-245 771.0
HKD1_k127_537290_20 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000004305 164.0
HKD1_k127_537290_21 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000001525 175.0
HKD1_k127_537290_22 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000002671 152.0
HKD1_k127_537290_23 Protein of unknown function (DUF3829) - - - 0.00000000000000000000000000000000000004248 156.0
HKD1_k127_537290_24 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000001083 114.0
HKD1_k127_537290_25 AntiSigma factor - - - 0.000007508 57.0
HKD1_k127_537290_3 oligoendopeptidase F K08602 - - 2.137e-242 754.0
HKD1_k127_537290_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 7.209e-233 728.0
HKD1_k127_537290_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.304e-226 711.0
HKD1_k127_537290_6 ABC1 family - - - 8.559e-218 683.0
HKD1_k127_537290_7 GDP-mannose 4,6 dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 582.0
HKD1_k127_537290_8 transhydrogenase subunit alpha K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 533.0
HKD1_k127_537290_9 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 488.0
HKD1_k127_537876_0 COG0665 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 587.0
HKD1_k127_537876_1 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 420.0
HKD1_k127_537876_2 racemase activity, acting on amino acids and derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 381.0
HKD1_k127_537876_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 348.0
HKD1_k127_537876_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006578 320.0
HKD1_k127_537876_5 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000434 224.0
HKD1_k127_537876_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000006528 175.0
HKD1_k127_537876_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000001296 155.0
HKD1_k127_5410928_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 494.0
HKD1_k127_5410928_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 481.0
HKD1_k127_5410928_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 463.0
HKD1_k127_5410928_3 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 462.0
HKD1_k127_5410928_4 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 301.0
HKD1_k127_5410928_5 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 253.0
HKD1_k127_5425950_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 6.599e-228 723.0
HKD1_k127_5425950_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 454.0
HKD1_k127_5425950_2 cytochrome c oxidase K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 416.0
HKD1_k127_5425950_3 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
HKD1_k127_5425950_4 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000002642 233.0
HKD1_k127_5425950_5 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000000000000000000000000000000000000000000002326 226.0
HKD1_k127_5425950_6 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000001745 153.0
HKD1_k127_5425950_7 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000001849 115.0
HKD1_k127_5425950_8 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000003463 108.0
HKD1_k127_5425950_9 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000002299 94.0
HKD1_k127_5487257_0 2Fe-2S iron-sulfur cluster binding domain K22086 - 1.5.99.5 0.0 1151.0
HKD1_k127_5487257_1 FAD dependent oxidoreductase K22084 - 1.5.99.5 1.902e-220 690.0
HKD1_k127_5487257_10 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 343.0
HKD1_k127_5487257_11 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 335.0
HKD1_k127_5487257_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 336.0
HKD1_k127_5487257_13 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 323.0
HKD1_k127_5487257_14 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
HKD1_k127_5487257_15 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002961 256.0
HKD1_k127_5487257_16 transcriptional regulator - - - 0.0000000000000000000000000000000000001516 150.0
HKD1_k127_5487257_17 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000003406 154.0
HKD1_k127_5487257_18 Sarcosine oxidase, gamma subunit K22087 - 1.5.99.5 0.000000000000000000000000000000000006367 152.0
HKD1_k127_5487257_19 sarcosine oxidase K00304,K22085 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000005924 120.0
HKD1_k127_5487257_2 ABC-type dipeptide transport system periplasmic component K02033,K02035,K13889 - - 3.733e-204 647.0
HKD1_k127_5487257_3 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 498.0
HKD1_k127_5487257_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 469.0
HKD1_k127_5487257_5 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 448.0
HKD1_k127_5487257_6 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 397.0
HKD1_k127_5487257_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 383.0
HKD1_k127_5487257_8 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 387.0
HKD1_k127_5487257_9 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 383.0
HKD1_k127_5503605_0 PAS PAC domain-containing protein - - - 4.964e-304 951.0
HKD1_k127_5503605_1 reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 519.0
HKD1_k127_5503605_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000001114 96.0
HKD1_k127_5503605_3 Cytochrome c - - - 0.00000000000000003878 88.0
HKD1_k127_5512416_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1045.0
HKD1_k127_5512416_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 483.0
HKD1_k127_5512416_2 - - - - 0.00000000000000000000000000006963 129.0
HKD1_k127_5518408_0 Belongs to the thiolase family K00626 - 2.3.1.9 1.397e-208 670.0
HKD1_k127_5518408_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 592.0
HKD1_k127_5518408_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 388.0
HKD1_k127_5518408_3 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000001876 177.0
HKD1_k127_5518408_4 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000004345 116.0
HKD1_k127_5518408_5 - - - - 0.000008926 51.0
HKD1_k127_5521107_0 Aconitase family (aconitate hydratase) - - - 4.631e-248 773.0
HKD1_k127_5521107_1 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 553.0
HKD1_k127_5521107_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 447.0
HKD1_k127_5521107_3 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 434.0
HKD1_k127_5521107_4 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 373.0
HKD1_k127_5521107_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 374.0
HKD1_k127_5521107_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.000000000000000000000000000000000000000007217 156.0
HKD1_k127_5521107_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000002139 127.0
HKD1_k127_5521107_8 - - - - 0.000001484 59.0
HKD1_k127_5523620_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.875e-222 702.0
HKD1_k127_5523620_1 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 573.0
HKD1_k127_5523620_10 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 362.0
HKD1_k127_5523620_11 AAA domain, putative AbiEii toxin, Type IV TA system K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 316.0
HKD1_k127_5523620_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000673 280.0
HKD1_k127_5523620_13 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002472 261.0
HKD1_k127_5523620_14 Transcriptional regulatory protein, C terminal K14981 - - 0.0000000000000000000000077 111.0
HKD1_k127_5523620_15 - - - - 0.00000000000000004411 89.0
HKD1_k127_5523620_16 - - - - 0.000000000008733 74.0
HKD1_k127_5523620_2 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 588.0
HKD1_k127_5523620_3 Binding-protein-dependent transport system inner membrane component K02033 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 514.0
HKD1_k127_5523620_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 485.0
HKD1_k127_5523620_5 P4 family phage plasmid primase K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 485.0
HKD1_k127_5523620_6 acid transport K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 434.0
HKD1_k127_5523620_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 426.0
HKD1_k127_5523620_8 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 381.0
HKD1_k127_5523620_9 ATPases associated with a variety of cellular activities K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 382.0
HKD1_k127_5612498_0 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 610.0
HKD1_k127_5612498_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 533.0
HKD1_k127_5612498_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 494.0
HKD1_k127_5612498_3 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 377.0
HKD1_k127_5612498_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
HKD1_k127_5612498_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003046 244.0
HKD1_k127_5612498_6 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001963 208.0
HKD1_k127_5612498_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000009401 151.0
HKD1_k127_5621905_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1204.0
HKD1_k127_5621905_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1059.0
HKD1_k127_5621905_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 471.0
HKD1_k127_5621905_11 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 454.0
HKD1_k127_5621905_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 460.0
HKD1_k127_5621905_13 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 438.0
HKD1_k127_5621905_14 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 424.0
HKD1_k127_5621905_15 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 402.0
HKD1_k127_5621905_16 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 393.0
HKD1_k127_5621905_17 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 383.0
HKD1_k127_5621905_18 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 338.0
HKD1_k127_5621905_19 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 317.0
HKD1_k127_5621905_2 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - - 4.225e-317 987.0
HKD1_k127_5621905_20 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 315.0
HKD1_k127_5621905_21 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
HKD1_k127_5621905_22 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 302.0
HKD1_k127_5621905_23 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 299.0
HKD1_k127_5621905_24 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004571 288.0
HKD1_k127_5621905_25 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000004146 225.0
HKD1_k127_5621905_26 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002509 206.0
HKD1_k127_5621905_27 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000002362 207.0
HKD1_k127_5621905_28 - - - - 0.000000000000000000000000000000000000000000000000000004242 194.0
HKD1_k127_5621905_29 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000002428 191.0
HKD1_k127_5621905_3 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 5.034e-254 811.0
HKD1_k127_5621905_30 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000225 177.0
HKD1_k127_5621905_31 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000003005 158.0
HKD1_k127_5621905_32 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000002719 152.0
HKD1_k127_5621905_33 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000001563 147.0
HKD1_k127_5621905_34 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000246 101.0
HKD1_k127_5621905_35 sulfurtransferase - - - 0.00000000000000000007688 93.0
HKD1_k127_5621905_36 Protein of unknown function (DUF2783) - - - 0.0000000000000003448 83.0
HKD1_k127_5621905_37 Universal stress protein family - - - 0.0000000000005538 75.0
HKD1_k127_5621905_38 Belongs to the ompA family - - - 0.000001383 55.0
HKD1_k127_5621905_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K08295 - 6.2.1.32 3.132e-247 775.0
HKD1_k127_5621905_5 FAD binding domain K05712 - 1.14.13.127 7.554e-203 644.0
HKD1_k127_5621905_6 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 610.0
HKD1_k127_5621905_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 568.0
HKD1_k127_5621905_8 COG1454 Alcohol dehydrogenase, class IV K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 530.0
HKD1_k127_5621905_9 Reductase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 509.0
HKD1_k127_5625769_0 FAD dependent oxidoreductase - - - 4.041e-248 773.0
HKD1_k127_5625769_1 Protein of unknown function (DUF521) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 560.0
HKD1_k127_5625769_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 512.0
HKD1_k127_5625769_3 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 488.0
HKD1_k127_5625769_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 471.0
HKD1_k127_5625769_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 336.0
HKD1_k127_5625769_6 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001978 295.0
HKD1_k127_5625769_7 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003398 297.0
HKD1_k127_5625769_8 Protein of unknown function DUF126 - - - 0.0000000000000000000000000000000000000000001375 166.0
HKD1_k127_5625769_9 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000000000000000000000003369 118.0
HKD1_k127_563772_0 ABC-type dipeptide transport system periplasmic component K02035 - - 1.328e-291 903.0
HKD1_k127_563772_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 3.385e-288 888.0
HKD1_k127_563772_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000652 175.0
HKD1_k127_563772_11 ThiS family K03636 - - 0.00000000000000000000000000006226 120.0
HKD1_k127_563772_12 Transposase K07492 - - 0.000000000000713 68.0
HKD1_k127_563772_13 CHAT domain - - - 0.00000000001147 67.0
HKD1_k127_563772_14 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0002425 44.0
HKD1_k127_563772_2 protein related to plant photosystem II stability assembly factor - - - 1.607e-202 644.0
HKD1_k127_563772_3 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 557.0
HKD1_k127_563772_4 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 546.0
HKD1_k127_563772_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 501.0
HKD1_k127_563772_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 423.0
HKD1_k127_563772_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 314.0
HKD1_k127_563772_8 Domain of unknown function (DUF1993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
HKD1_k127_563772_9 - - - - 0.000000000000000000000000000000000000000000000000000003894 201.0
HKD1_k127_5646626_0 Periplasmic binding protein domain K01999 - - 4.983e-196 621.0
HKD1_k127_5646626_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 498.0
HKD1_k127_5646626_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 415.0
HKD1_k127_5646626_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 413.0
HKD1_k127_5646626_4 Domain of unknown function DUF108 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
HKD1_k127_5646626_5 histidine kinase HAMP region domain protein K03406 - - 0.000004675 49.0
HKD1_k127_5682562_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 488.0
HKD1_k127_5682562_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 456.0
HKD1_k127_5682562_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 384.0
HKD1_k127_5682562_3 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 326.0
HKD1_k127_5682562_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000001468 234.0
HKD1_k127_5682562_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18307 - - 0.0000000000000000000000000000000000000000000000000000000008327 203.0
HKD1_k127_5682562_6 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000001002 198.0
HKD1_k127_5682562_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000002689 98.0
HKD1_k127_5693830_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1418.0
HKD1_k127_5693830_1 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 544.0
HKD1_k127_5693830_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 411.0
HKD1_k127_5693830_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 374.0
HKD1_k127_5693830_4 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000001446 214.0
HKD1_k127_5693830_5 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000002069 203.0
HKD1_k127_5693830_6 addiction module toxin RelE StbE family K19092 - - 0.000000000000000000003126 99.0
HKD1_k127_5693830_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000004237 65.0
HKD1_k127_5693830_8 Ribbon-helix-helix protein, copG family - - - 0.00000000004501 77.0
HKD1_k127_5694053_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 572.0
HKD1_k127_5694053_1 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004097 279.0
HKD1_k127_5694053_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001117 272.0
HKD1_k127_5694053_3 COG4177 ABC-type branched-chain amino acid transport system, permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000003101 240.0
HKD1_k127_5694053_4 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000145 215.0
HKD1_k127_5694053_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000007146 173.0
HKD1_k127_5694053_6 ABC transporter K01996 - - 0.0000000000000000000000000003151 115.0
HKD1_k127_5714460_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.706e-249 791.0
HKD1_k127_5714460_1 FAD binding domain - - - 1.203e-199 638.0
HKD1_k127_5714460_2 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 439.0
HKD1_k127_5714460_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 412.0
HKD1_k127_5714460_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 412.0
HKD1_k127_5714460_5 Chaperone SurA K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 399.0
HKD1_k127_5714460_6 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 382.0
HKD1_k127_5714460_7 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 352.0
HKD1_k127_5714460_8 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 317.0
HKD1_k127_5714460_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000001011 190.0
HKD1_k127_5728842_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1192.0
HKD1_k127_5728842_1 FAD dependent oxidoreductase K19191 - 1.5.3.19 0.0 1095.0
HKD1_k127_5728842_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 441.0
HKD1_k127_5728842_11 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 445.0
HKD1_k127_5728842_12 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 410.0
HKD1_k127_5728842_13 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 378.0
HKD1_k127_5728842_14 Carbon monoxide dehydrogenase subunit G (CoxG) K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 386.0
HKD1_k127_5728842_15 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 350.0
HKD1_k127_5728842_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 329.0
HKD1_k127_5728842_17 dehydrogenase and related dehydrogenases K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 334.0
HKD1_k127_5728842_18 FAD binding domain in molybdopterin dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001492 295.0
HKD1_k127_5728842_19 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005818 302.0
HKD1_k127_5728842_2 FAD dependent oxidoreductase central domain - - - 0.0 1017.0
HKD1_k127_5728842_20 PFAM Short-chain dehydrogenase reductase SDR K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000005827 218.0
HKD1_k127_5728842_21 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000004926 196.0
HKD1_k127_5728842_22 Ring hydroxylating beta subunit K16320 - 1.14.12.1 0.0000000000000000000000000000000000000000002418 180.0
HKD1_k127_5728842_3 dioxygenase alpha subunit K16319 - 1.14.12.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 606.0
HKD1_k127_5728842_4 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 602.0
HKD1_k127_5728842_5 Oxidative deamination of D-amino acids - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 509.0
HKD1_k127_5728842_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 510.0
HKD1_k127_5728842_7 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 472.0
HKD1_k127_5728842_8 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 449.0
HKD1_k127_5728842_9 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 452.0
HKD1_k127_5751161_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 548.0
HKD1_k127_5751161_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 337.0
HKD1_k127_5751161_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 291.0
HKD1_k127_5751161_3 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
HKD1_k127_5751161_4 Sarcosine oxidase, beta subunit K00303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001686 257.0
HKD1_k127_577363_0 Rhodanese Homology Domain - - - 1.475e-204 655.0
HKD1_k127_577363_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 388.0
HKD1_k127_577363_2 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.000000000000000000000005013 118.0
HKD1_k127_577363_3 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000001471 65.0
HKD1_k127_5808983_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1160.0
HKD1_k127_5808983_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.848e-290 904.0
HKD1_k127_5808983_10 Dihydroneopterin aldolase - - - 0.000000000000000000000000000000003709 133.0
HKD1_k127_5808983_11 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000004056 122.0
HKD1_k127_5808983_12 peptidyl-tyrosine sulfation - - - 0.00000000000003868 82.0
HKD1_k127_5808983_2 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 586.0
HKD1_k127_5808983_3 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 360.0
HKD1_k127_5808983_4 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004406 264.0
HKD1_k127_5808983_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
HKD1_k127_5808983_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000000000000001216 244.0
HKD1_k127_5808983_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003568 234.0
HKD1_k127_5808983_8 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000003332 228.0
HKD1_k127_5808983_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000000000000000022 138.0
HKD1_k127_5817351_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 528.0
HKD1_k127_5817351_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 362.0
HKD1_k127_5817351_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 351.0
HKD1_k127_5817351_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 346.0
HKD1_k127_5817351_4 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 286.0
HKD1_k127_5817351_5 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000005699 245.0
HKD1_k127_5905467_0 COG0841 Cation multidrug efflux pump - - - 0.0 1578.0
HKD1_k127_5905467_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 6.536e-200 634.0
HKD1_k127_5905467_10 Major facilitator Superfamily - - - 0.0000000000002782 72.0
HKD1_k127_5905467_2 FAD dependent oxidoreductase - - - 1.761e-195 618.0
HKD1_k127_5905467_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 509.0
HKD1_k127_5905467_4 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 512.0
HKD1_k127_5905467_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 473.0
HKD1_k127_5905467_6 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 334.0
HKD1_k127_5905467_7 dehydratase K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002054 276.0
HKD1_k127_5905467_8 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000001859 226.0
HKD1_k127_5905467_9 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000002336 186.0
HKD1_k127_5909441_0 CHAT domain - - - 3.917e-270 862.0
HKD1_k127_5909441_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 4.085e-251 796.0
HKD1_k127_5909441_10 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 316.0
HKD1_k127_5909441_11 - - - - 0.00000000000000000000000000000000000000000000000000000004335 206.0
HKD1_k127_5909441_12 Patatin-like phospholipase - - - 0.0000000000000001934 84.0
HKD1_k127_5909441_2 transcriptional regulator - - - 7.914e-220 692.0
HKD1_k127_5909441_3 CHASE2 K01768 - 4.6.1.1 1.335e-217 693.0
HKD1_k127_5909441_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.147e-203 647.0
HKD1_k127_5909441_5 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 477.0
HKD1_k127_5909441_6 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 464.0
HKD1_k127_5909441_7 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 369.0
HKD1_k127_5909441_8 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 353.0
HKD1_k127_5909441_9 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 336.0
HKD1_k127_5935233_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.583e-290 910.0
HKD1_k127_5935233_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 447.0
HKD1_k127_5935233_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 400.0
HKD1_k127_5935233_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 334.0
HKD1_k127_593761_0 Thiamine pyrophosphate enzyme, central domain K01577 - 4.1.1.8 5.311e-306 941.0
HKD1_k127_593761_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 2.409e-242 760.0
HKD1_k127_593761_10 EVE domain - - - 0.000000000000000000000000000000000000000000000000001647 198.0
HKD1_k127_593761_11 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000002312 174.0
HKD1_k127_593761_12 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000000037 139.0
HKD1_k127_593761_13 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000000003342 134.0
HKD1_k127_593761_14 CoA binding domain K09181 - - 0.0000000000000000000000004645 109.0
HKD1_k127_593761_2 Homospermidine synthase K00808 - 2.5.1.44 1.836e-236 739.0
HKD1_k127_593761_3 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 440.0
HKD1_k127_593761_4 trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 355.0
HKD1_k127_593761_5 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 344.0
HKD1_k127_593761_6 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 301.0
HKD1_k127_593761_7 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000001653 231.0
HKD1_k127_593761_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000001794 236.0
HKD1_k127_593761_9 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000000000258 208.0
HKD1_k127_6000263_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.765e-201 636.0
HKD1_k127_6000263_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 383.0
HKD1_k127_6000263_2 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 328.0
HKD1_k127_6000263_3 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008067 276.0
HKD1_k127_6000263_4 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000447 237.0
HKD1_k127_6000263_5 ROS/MUCR transcriptional regulator protein - - - 0.000000000000000000000000000000000000000000000000000000009738 207.0
HKD1_k127_6000263_6 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000001478 99.0
HKD1_k127_6034840_0 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 469.0
HKD1_k127_6034840_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 402.0
HKD1_k127_6034840_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 317.0
HKD1_k127_6034840_3 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000005909 235.0
HKD1_k127_6034840_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000002922 139.0
HKD1_k127_6034840_5 PFAM transglutaminase family protein cysteine peptidase, BTLCP - - - 0.0000000000000000006405 91.0
HKD1_k127_6037934_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.912e-222 696.0
HKD1_k127_6037934_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 1.592e-196 617.0
HKD1_k127_6037934_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000004549 198.0
HKD1_k127_6037934_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000001461 166.0
HKD1_k127_6037934_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000001728 156.0
HKD1_k127_6037934_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000008881 152.0
HKD1_k127_6037934_14 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000001651 90.0
HKD1_k127_6037934_15 Plasmid stabilization system K07746 - - 0.00005964 49.0
HKD1_k127_6037934_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 344.0
HKD1_k127_6037934_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 303.0
HKD1_k127_6037934_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003253 278.0
HKD1_k127_6037934_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003057 254.0
HKD1_k127_6037934_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000007579 227.0
HKD1_k127_6037934_7 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000004547 215.0
HKD1_k127_6037934_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000007291 218.0
HKD1_k127_6037934_9 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000007056 212.0
HKD1_k127_6061990_0 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 609.0
HKD1_k127_6061990_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 590.0
HKD1_k127_6061990_10 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000005896 229.0
HKD1_k127_6061990_11 Gaf domain - - - 0.00000000000000000000000000000000000000000000000101 192.0
HKD1_k127_6061990_12 enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000003342 133.0
HKD1_k127_6061990_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000006879 129.0
HKD1_k127_6061990_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 397.0
HKD1_k127_6061990_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 323.0
HKD1_k127_6061990_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 307.0
HKD1_k127_6061990_5 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002943 293.0
HKD1_k127_6061990_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
HKD1_k127_6061990_7 Alpha beta hydrolase K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000002144 276.0
HKD1_k127_6061990_8 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006797 246.0
HKD1_k127_6061990_9 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000171 235.0
HKD1_k127_6082506_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 3.478e-260 808.0
HKD1_k127_6082506_1 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.44e-220 697.0
HKD1_k127_6082506_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 541.0
HKD1_k127_6082506_4 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000002129 213.0
HKD1_k127_6082506_6 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000005571 124.0
HKD1_k127_6093265_0 WD40 repeats K20332 - - 1.321e-269 878.0
HKD1_k127_6093265_1 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 599.0
HKD1_k127_6093265_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 502.0
HKD1_k127_6093265_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007208 283.0
HKD1_k127_6093265_4 transglycosylase - - - 0.000000000000000000000000000000000000000000001689 174.0
HKD1_k127_6093265_5 - - - - 0.000000000000382 77.0
HKD1_k127_6097475_0 PLD-like domain - - - 7.918e-218 695.0
HKD1_k127_6097475_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.339e-205 671.0
HKD1_k127_6097475_2 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 542.0
HKD1_k127_6097475_3 malic enzyme K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 413.0
HKD1_k127_6097475_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 305.0
HKD1_k127_6097475_5 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003983 277.0
HKD1_k127_6097475_6 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008749 268.0
HKD1_k127_6097475_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000002732 226.0
HKD1_k127_6110408_0 Formate dehydrogenase subunit alpha - - - 0.0 1573.0
HKD1_k127_6110408_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 9.555e-314 973.0
HKD1_k127_6110408_10 alpha beta - - - 0.000000000000000000000000000000000000000000000000006048 192.0
HKD1_k127_6110408_11 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000002187 178.0
HKD1_k127_6110408_12 Haem-degrading - - - 0.00000000000000000000000000000006052 131.0
HKD1_k127_6110408_2 Dehydrogenase K00122 - 1.17.1.9 4.027e-312 962.0
HKD1_k127_6110408_3 PFAM major facilitator superfamily MFS_1 K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 554.0
HKD1_k127_6110408_4 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 515.0
HKD1_k127_6110408_5 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 417.0
HKD1_k127_6110408_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 385.0
HKD1_k127_6110408_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 336.0
HKD1_k127_6110408_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001542 279.0
HKD1_k127_6110408_9 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000001168 207.0
HKD1_k127_612553_0 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 570.0
HKD1_k127_612553_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 535.0
HKD1_k127_612553_2 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 381.0
HKD1_k127_612553_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 336.0
HKD1_k127_612553_4 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000001991 145.0
HKD1_k127_612553_5 Modulates RecA activity K03565 - - 0.000000000000000000000000000000002799 136.0
HKD1_k127_612553_6 Methyltransferase domain - - - 0.00000000000000000000001937 112.0
HKD1_k127_612553_7 - - - - 0.00000003992 63.0
HKD1_k127_6147131_0 Belongs to the binding-protein-dependent transport system permease family - - - 2.551e-237 750.0
HKD1_k127_6147131_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 505.0
HKD1_k127_6147131_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 336.0
HKD1_k127_6147131_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 289.0
HKD1_k127_6147131_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000002459 217.0
HKD1_k127_6147131_5 NIPSNAP - - - 0.000000000000000000000000000000000000000002525 161.0
HKD1_k127_6147131_6 PAS domain - - - 0.0000000000000000000000000000001076 132.0
HKD1_k127_6147131_7 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000002689 128.0
HKD1_k127_6147131_8 PFAM TENA THI-4 protein Coenzyme PQQ biosynthesis protein C K06137 - 1.3.3.11 0.0006734 51.0
HKD1_k127_6169334_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.216e-259 808.0
HKD1_k127_6169334_1 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 568.0
HKD1_k127_6169334_10 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
HKD1_k127_6169334_11 COG1177 ABC-type spermidine putrescine transport system, permease component II K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 356.0
HKD1_k127_6169334_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 336.0
HKD1_k127_6169334_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 332.0
HKD1_k127_6169334_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 305.0
HKD1_k127_6169334_15 MlaD protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001477 284.0
HKD1_k127_6169334_16 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 264.0
HKD1_k127_6169334_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009743 270.0
HKD1_k127_6169334_18 Glycosyl transferase, family 2 K01002 - 2.7.8.20 0.00000000000000000000000000000000000000000000000000000000000008543 230.0
HKD1_k127_6169334_19 TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K13006,K19429 - - 0.00000000000000000000000000000000000000000000000000000001128 205.0
HKD1_k127_6169334_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 563.0
HKD1_k127_6169334_20 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000000000000000008342 192.0
HKD1_k127_6169334_21 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000004673 183.0
HKD1_k127_6169334_22 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000302 145.0
HKD1_k127_6169334_23 Glycine zipper 2TM domain - - - 0.0000000000103 71.0
HKD1_k127_6169334_24 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.00002354 48.0
HKD1_k127_6169334_3 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 440.0
HKD1_k127_6169334_4 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 413.0
HKD1_k127_6169334_5 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 386.0
HKD1_k127_6169334_6 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 386.0
HKD1_k127_6169334_7 Putrescine transport system permease K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
HKD1_k127_6169334_8 MATE efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 379.0
HKD1_k127_6169334_9 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 355.0
HKD1_k127_6176308_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 602.0
HKD1_k127_6176308_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 551.0
HKD1_k127_6176308_2 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 503.0
HKD1_k127_6176308_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001542 287.0
HKD1_k127_6176308_4 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000002557 171.0
HKD1_k127_6176308_5 - - - - 0.0000000009836 61.0
HKD1_k127_619036_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1092.0
HKD1_k127_619036_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1063.0
HKD1_k127_619036_10 - - - - 0.0000000000309 68.0
HKD1_k127_619036_11 - - - - 0.000006144 59.0
HKD1_k127_619036_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 604.0
HKD1_k127_619036_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 588.0
HKD1_k127_619036_4 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 451.0
HKD1_k127_619036_5 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008081 265.0
HKD1_k127_619036_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002458 272.0
HKD1_k127_619036_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000002257 181.0
HKD1_k127_619036_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000001506 105.0
HKD1_k127_6200159_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0 1143.0
HKD1_k127_6200159_1 amidohydrolase K12941 - - 1.079e-246 769.0
HKD1_k127_6200159_10 Allophanate hydrolase K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000003745 161.0
HKD1_k127_6200159_11 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.0000000000000000000000000000008401 132.0
HKD1_k127_6200159_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 517.0
HKD1_k127_6200159_3 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 498.0
HKD1_k127_6200159_4 Spermidine putrescine-binding periplasmic protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 456.0
HKD1_k127_6200159_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 396.0
HKD1_k127_6200159_6 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 390.0
HKD1_k127_6200159_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 318.0
HKD1_k127_6200159_8 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 309.0
HKD1_k127_6200159_9 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003541 285.0
HKD1_k127_6233498_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.255e-219 688.0
HKD1_k127_6233498_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.284e-202 641.0
HKD1_k127_6233498_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 602.0
HKD1_k127_6233498_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 507.0
HKD1_k127_6233498_4 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 457.0
HKD1_k127_6233498_5 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000006769 59.0
HKD1_k127_623425_0 Pyridoxal-dependent decarboxylase conserved domain - - - 1.73e-226 710.0
HKD1_k127_623425_1 ATP-grasp domain K09181 - - 8.953e-197 635.0
HKD1_k127_623425_2 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 555.0
HKD1_k127_623425_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 470.0
HKD1_k127_623425_4 deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 409.0
HKD1_k127_623425_5 Arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 392.0
HKD1_k127_623425_6 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 362.0
HKD1_k127_623425_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 285.0
HKD1_k127_623425_9 Cupin domain - - - 0.0000000000000000000000000000003655 131.0
HKD1_k127_6305565_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1009.0
HKD1_k127_6305565_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 548.0
HKD1_k127_6305565_2 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 477.0
HKD1_k127_6305565_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 363.0
HKD1_k127_6368805_0 CoA-transferase family III K14470 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015977,GO:0016853,GO:0016866,GO:0016867,GO:0043427,GO:0071704 5.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 476.0
HKD1_k127_6368805_1 Major facilitator Superfamily K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 344.0
HKD1_k127_6368805_2 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 323.0
HKD1_k127_6368805_3 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000003203 229.0
HKD1_k127_6368805_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000001453 94.0
HKD1_k127_637122_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.322e-280 873.0
HKD1_k127_637122_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 510.0
HKD1_k127_6379162_0 Glycosyl hydrolases family 15 - - - 1.399e-224 724.0
HKD1_k127_6379162_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.699e-198 627.0
HKD1_k127_6379162_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 375.0
HKD1_k127_6379162_11 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 323.0
HKD1_k127_6379162_12 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002529 278.0
HKD1_k127_6379162_13 Trehalose-phosphatase K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000002954 189.0
HKD1_k127_6379162_14 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000006137 154.0
HKD1_k127_6379162_15 - - - - 0.0000000000000000000000000000000004529 143.0
HKD1_k127_6379162_16 TIGRFAM outer membrane autotransporter barrel domain - - - 0.00000000000000000000000000000005384 146.0
HKD1_k127_6379162_2 Domain of unknown function (DUF4070) - - - 4.426e-196 621.0
HKD1_k127_6379162_3 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 612.0
HKD1_k127_6379162_4 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 487.0
HKD1_k127_6379162_5 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 498.0
HKD1_k127_6379162_6 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 458.0
HKD1_k127_6379162_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 443.0
HKD1_k127_6379162_8 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 428.0
HKD1_k127_6379162_9 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 418.0
HKD1_k127_6460727_0 Belongs to the GcvT family K00302 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.3.1 4.3e-322 1007.0
HKD1_k127_6460727_1 Proton-conducting membrane transporter - - - 4.897e-242 764.0
HKD1_k127_6460727_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 294.0
HKD1_k127_6460727_11 oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 292.0
HKD1_k127_6460727_12 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005422 295.0
HKD1_k127_6460727_13 Polyhydroxyalkanoate synthesis repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000587 280.0
HKD1_k127_6460727_14 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009784 278.0
HKD1_k127_6460727_15 of the double-stranded beta helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007282 273.0
HKD1_k127_6460727_16 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007267 288.0
HKD1_k127_6460727_17 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000001771 202.0
HKD1_k127_6460727_18 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000008879 179.0
HKD1_k127_6460727_19 - - - - 0.0000000000000000000000000000000000000000000003206 168.0
HKD1_k127_6460727_2 Proton-conducting membrane transporter K12141 - - 1.639e-213 687.0
HKD1_k127_6460727_20 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.0000000000000000000000000000000001398 140.0
HKD1_k127_6460727_22 NADH dehydrogenase - - - 0.0000000000000000000000000000009434 123.0
HKD1_k127_6460727_23 - - - - 0.0004192 48.0
HKD1_k127_6460727_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 4.041e-209 663.0
HKD1_k127_6460727_4 Putative diguanylate phosphodiesterase - - - 3.068e-202 648.0
HKD1_k127_6460727_5 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00055,K00121 - 1.1.1.1,1.1.1.284,1.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 567.0
HKD1_k127_6460727_6 alpha/beta hydrolase fold K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 503.0
HKD1_k127_6460727_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 439.0
HKD1_k127_6460727_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 440.0
HKD1_k127_6460727_9 fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 383.0
HKD1_k127_646909_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0 1018.0
HKD1_k127_646909_1 Amidohydrolase family K01464 - 3.5.2.2 3.328e-224 703.0
HKD1_k127_646909_10 AntiSigma factor - - - 0.000000000000000000000000000717 129.0
HKD1_k127_646909_11 Antitoxin component of a type II toxin-antitoxin (TA) system. Functions as an mRNA interferase antitoxin K18843 - - 0.0000000000000000000001418 102.0
HKD1_k127_646909_12 Cytochrome c - - - 0.000000000000000004408 87.0
HKD1_k127_646909_13 - K07339 - - 0.000000000000001426 78.0
HKD1_k127_646909_2 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 562.0
HKD1_k127_646909_3 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 363.0
HKD1_k127_646909_4 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 325.0
HKD1_k127_646909_5 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 278.0
HKD1_k127_646909_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000004447 230.0
HKD1_k127_646909_7 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000001004 174.0
HKD1_k127_646909_8 Sigma-70 region 4 type 2 K03088 - - 0.0000000000000000000000000000000000000000004899 163.0
HKD1_k127_646909_9 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000002539 141.0
HKD1_k127_649776_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1051.0
HKD1_k127_649776_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1027.0
HKD1_k127_649776_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001327 258.0
HKD1_k127_649776_11 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.000000000000000000000000000000000000005906 162.0
HKD1_k127_649776_13 Putative zinc-finger - - - 0.00000000004919 64.0
HKD1_k127_649776_2 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 568.0
HKD1_k127_649776_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 598.0
HKD1_k127_649776_4 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 498.0
HKD1_k127_649776_5 Belongs to the LDH2 MDH2 oxidoreductase family K00073,K13574 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 448.0
HKD1_k127_649776_6 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 427.0
HKD1_k127_649776_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 361.0
HKD1_k127_649776_8 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 336.0
HKD1_k127_649776_9 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005974 282.0
HKD1_k127_6511151_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.0 1178.0
HKD1_k127_6511151_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 1.018e-264 848.0
HKD1_k127_6511151_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 434.0
HKD1_k127_6511151_3 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 428.0
HKD1_k127_6511151_4 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 419.0
HKD1_k127_6511151_5 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 410.0
HKD1_k127_6511151_6 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 387.0
HKD1_k127_6511151_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000000002519 188.0
HKD1_k127_6511151_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000006895 175.0
HKD1_k127_6511151_9 Usg-like family - - - 0.0000000000000000000000000000000001949 134.0
HKD1_k127_6512614_0 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 494.0
HKD1_k127_6512614_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 436.0
HKD1_k127_6512614_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 428.0
HKD1_k127_6512614_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 383.0
HKD1_k127_6512614_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 362.0
HKD1_k127_6512614_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008406 268.0
HKD1_k127_6512614_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006177 259.0
HKD1_k127_6512614_7 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000003088 225.0
HKD1_k127_6512614_8 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000000006108 215.0
HKD1_k127_6512614_9 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000000000000000005045 201.0
HKD1_k127_6528200_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 569.0
HKD1_k127_6528200_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000001177 260.0
HKD1_k127_6528200_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000002145 205.0
HKD1_k127_6528200_3 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000002983 102.0
HKD1_k127_6528200_4 amino acid adenylation domain protein K04780 - - 0.0001502 52.0
HKD1_k127_6537126_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 453.0
HKD1_k127_6537126_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 391.0
HKD1_k127_6537126_10 - - - - 0.000004771 55.0
HKD1_k127_6537126_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 373.0
HKD1_k127_6537126_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 321.0
HKD1_k127_6537126_4 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 313.0
HKD1_k127_6537126_5 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001043 294.0
HKD1_k127_6537126_6 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000004256 228.0
HKD1_k127_6537126_7 COG3637 Opacity protein and related surface antigens - - - 0.00000000000000000000000000000000000000000000000000000000008211 218.0
HKD1_k127_6537126_8 COG3637 Opacity protein and related surface antigens - - - 0.00000000000000000000000000000000000000000000000000000008712 209.0
HKD1_k127_6537126_9 COG1419 Flagellar GTP-binding protein K02404 - - 0.000000000000000000000001776 115.0
HKD1_k127_6569067_0 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 486.0
HKD1_k127_6569067_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 460.0
HKD1_k127_6569067_2 OpgC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 427.0
HKD1_k127_6569067_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 409.0
HKD1_k127_6569067_4 NADP-dependent oxidoreductase K00001,K07119 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 348.0
HKD1_k127_6569067_5 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000005623 232.0
HKD1_k127_6569067_6 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000001688 220.0
HKD1_k127_6569067_7 Polysaccharide biosynthesis protein K08679,K17947 - 5.1.3.25,5.1.3.6 0.00000000000005627 72.0
HKD1_k127_6569073_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.743e-285 904.0
HKD1_k127_6569073_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.559e-267 827.0
HKD1_k127_6569073_10 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000224 223.0
HKD1_k127_6569073_11 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000001299 190.0
HKD1_k127_6569073_12 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000005459 179.0
HKD1_k127_6569073_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000007679 151.0
HKD1_k127_6569073_15 PAS domain - - - 0.00000000000000000000000000000000106 136.0
HKD1_k127_6569073_16 GYD domain - - - 0.00000000000000000000000001963 112.0
HKD1_k127_6569073_2 AMP-binding enzyme - - - 4.717e-206 653.0
HKD1_k127_6569073_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 610.0
HKD1_k127_6569073_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 583.0
HKD1_k127_6569073_5 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 551.0
HKD1_k127_6569073_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 422.0
HKD1_k127_6569073_7 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 378.0
HKD1_k127_6569073_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 346.0
HKD1_k127_6569073_9 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000000000203 245.0
HKD1_k127_6615023_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.001e-279 876.0
HKD1_k127_6615023_1 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 295.0
HKD1_k127_6615023_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000502 256.0
HKD1_k127_6620704_0 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.028e-227 713.0
HKD1_k127_6620704_1 Conserved hypothetical protein 698 - - - 1.73e-226 710.0
HKD1_k127_6620704_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 426.0
HKD1_k127_6620704_3 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 294.0
HKD1_k127_6620704_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007827 289.0
HKD1_k127_6620704_5 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 261.0
HKD1_k127_6620704_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000001092 205.0
HKD1_k127_6620704_7 Protein of unknown function (DUF1045) - - - 0.0000000000000000000000000000000000000000000000000008802 191.0
HKD1_k127_6620704_8 phosphonate metabolism protein PhnM K06162 - 3.6.1.63 0.00000000000000000000000000000000000000002705 154.0
HKD1_k127_6641170_0 Hydantoinase B/oxoprolinase - - - 2.046e-234 729.0
HKD1_k127_6641170_1 Glycosyl transferase family 21 K03669 - - 3.235e-198 636.0
HKD1_k127_6641170_10 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000005097 110.0
HKD1_k127_6641170_11 GAF domain - - - 0.0000000004066 74.0
HKD1_k127_6641170_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 422.0
HKD1_k127_6641170_3 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 418.0
HKD1_k127_6641170_4 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 338.0
HKD1_k127_6641170_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002871 258.0
HKD1_k127_6641170_6 Haemolysin-III related K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000434 202.0
HKD1_k127_6641170_7 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000002147 208.0
HKD1_k127_6641170_8 cobalamin synthesis protein, P47K - - - 0.0000000000000000000000000000000000000005704 164.0
HKD1_k127_6641170_9 Subtilase family - - - 0.000000000000000000000000000000005256 145.0
HKD1_k127_6691009_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 7.692e-221 692.0
HKD1_k127_6691009_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 527.0
HKD1_k127_6691009_10 cheY-homologous receiver domain - - - 0.000000000000000646 90.0
HKD1_k127_6691009_2 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 424.0
HKD1_k127_6691009_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
HKD1_k127_6691009_4 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 321.0
HKD1_k127_6691009_5 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000003254 166.0
HKD1_k127_6691009_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000001625 159.0
HKD1_k127_6691009_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000004084 175.0
HKD1_k127_6691009_8 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000002584 134.0
HKD1_k127_6691009_9 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000003076 106.0
HKD1_k127_6696223_0 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 576.0
HKD1_k127_6696223_1 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 326.0
HKD1_k127_6696223_10 bond formation protein, DsbB - - - 0.000000000000000000000000000000002047 144.0
HKD1_k127_6696223_11 peroxiredoxin activity K01055,K01607 - 3.1.1.24,4.1.1.44 0.0000000000000005527 87.0
HKD1_k127_6696223_12 Hypoxia induced protein conserved region - - - 0.00000000000001956 74.0
HKD1_k127_6696223_2 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003837 257.0
HKD1_k127_6696223_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000009589 252.0
HKD1_k127_6696223_4 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001431 248.0
HKD1_k127_6696223_5 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000005391 241.0
HKD1_k127_6696223_6 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005162 223.0
HKD1_k127_6696223_7 MarR family - - - 0.0000000000000000000000000000000000000000000000008552 178.0
HKD1_k127_6696223_8 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000001373 170.0
HKD1_k127_6696223_9 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000002992 155.0
HKD1_k127_6806914_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 5.11e-255 826.0
HKD1_k127_6806914_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.482e-232 728.0
HKD1_k127_6806914_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 561.0
HKD1_k127_6806914_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 424.0
HKD1_k127_6820690_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 8.879e-274 857.0
HKD1_k127_6820690_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 502.0
HKD1_k127_6820690_2 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000001236 183.0
HKD1_k127_6842854_0 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 527.0
HKD1_k127_6842854_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 338.0
HKD1_k127_6842854_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 321.0
HKD1_k127_6842854_3 Transcriptional regulatory protein, C terminal K07659 - - 0.00000000000000000000000000000000000000000000000005151 185.0
HKD1_k127_6842854_4 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000000000002896 80.0
HKD1_k127_6847860_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 549.0
HKD1_k127_6847860_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 465.0
HKD1_k127_6847860_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 411.0
HKD1_k127_6847860_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001024 250.0
HKD1_k127_6847860_4 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000000001839 180.0
HKD1_k127_6853762_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 521.0
HKD1_k127_6853762_1 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 415.0
HKD1_k127_6853762_2 CHAP domain - - - 0.000000000000000000000000000000002594 136.0
HKD1_k127_6853762_3 - - - - 0.0000000000000000000004829 110.0
HKD1_k127_6853762_4 Rhodanese Homology Domain - - - 0.0000001081 59.0
HKD1_k127_6853762_5 Flp Fap pilin component K02651 - - 0.0000006275 54.0
HKD1_k127_6865057_0 leucine-zipper of insertion element IS481 K00986,K07497 - 2.7.7.49 1.113e-194 616.0
HKD1_k127_6865057_1 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 557.0
HKD1_k127_6865057_10 Endoribonuclease L-PSP K09021 - - 0.00000000000000000000000000000000000000000000000000000000001015 216.0
HKD1_k127_6865057_11 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.00000000000000000000000000000000000000000000000000704 196.0
HKD1_k127_6865057_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000003941 132.0
HKD1_k127_6865057_13 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000001307 136.0
HKD1_k127_6865057_14 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000003221 116.0
HKD1_k127_6865057_15 PFAM ABC transporter K02028,K09972 - 3.6.3.21 0.000000000000000000000005832 119.0
HKD1_k127_6865057_16 - - - - 0.0002115 50.0
HKD1_k127_6865057_17 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0003516 49.0
HKD1_k127_6865057_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 558.0
HKD1_k127_6865057_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 551.0
HKD1_k127_6865057_4 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 538.0
HKD1_k127_6865057_5 acid transport system permease K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 470.0
HKD1_k127_6865057_6 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 434.0
HKD1_k127_6865057_7 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 412.0
HKD1_k127_6865057_8 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 297.0
HKD1_k127_6865057_9 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
HKD1_k127_691082_0 Hydantoinase B/oxoprolinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 573.0
HKD1_k127_691082_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 404.0
HKD1_k127_691082_2 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 316.0
HKD1_k127_691082_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 292.0
HKD1_k127_691082_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000001544 260.0
HKD1_k127_691082_5 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000002324 234.0
HKD1_k127_691082_6 Domain of unknown function (DUF4919) - - - 0.0000000000000000000002017 110.0
HKD1_k127_691082_7 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000002195 93.0
HKD1_k127_6924276_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.771e-218 685.0
HKD1_k127_6924276_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 427.0
HKD1_k127_6924276_2 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 397.0
HKD1_k127_6924276_3 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 373.0
HKD1_k127_6924276_4 membrane protein, required for colicin V production K03558 - - 0.0000000003595 61.0
HKD1_k127_6924276_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000004314 55.0
HKD1_k127_695035_0 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
HKD1_k127_695035_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
HKD1_k127_695035_2 Transmembrane secretion effector K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001549 281.0
HKD1_k127_695035_3 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 271.0
HKD1_k127_695035_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000002928 191.0
HKD1_k127_695035_5 ABC transporter substrate binding protein - - - 0.00000000000000000000000002271 111.0
HKD1_k127_6985541_0 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 8.353e-202 651.0
HKD1_k127_6985541_1 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 571.0
HKD1_k127_6985541_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 566.0
HKD1_k127_6985541_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 520.0
HKD1_k127_6985541_4 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001398 260.0
HKD1_k127_6985541_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001055 249.0
HKD1_k127_6985541_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000008424 243.0
HKD1_k127_6985541_7 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000009477 228.0
HKD1_k127_6985541_8 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000102 136.0
HKD1_k127_6985541_9 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000001375 143.0
HKD1_k127_6986631_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 4.691e-211 662.0
HKD1_k127_6986631_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.86e-202 639.0
HKD1_k127_6986631_10 PFAM B3 4 domain protein - - - 0.0000000000000000000000000000000000001745 157.0
HKD1_k127_6986631_11 Protein of unknown function (DUF2948) - - - 0.000000000000000000000000003216 117.0
HKD1_k127_6986631_12 YCII-related domain K09780 - - 0.000000000000000000005684 95.0
HKD1_k127_6986631_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 583.0
HKD1_k127_6986631_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 518.0
HKD1_k127_6986631_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 492.0
HKD1_k127_6986631_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 498.0
HKD1_k127_6986631_6 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 335.0
HKD1_k127_6986631_7 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 320.0
HKD1_k127_6986631_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002195 288.0
HKD1_k127_6986631_9 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001005 256.0
HKD1_k127_6989399_0 DNA helicase K03654 - 3.6.4.12 1.297e-287 894.0
HKD1_k127_6989399_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 2.496e-243 767.0
HKD1_k127_6989399_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 381.0
HKD1_k127_6989399_3 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0000000000000000000000000000000000000007488 149.0
HKD1_k127_6989399_4 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000004817 104.0
HKD1_k127_7015936_0 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 601.0
HKD1_k127_7015936_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 421.0
HKD1_k127_7015936_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 290.0
HKD1_k127_7015936_3 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000006706 210.0
HKD1_k127_7015936_4 Methyltransferase K06968 - 2.1.1.186 0.00000004551 55.0
HKD1_k127_7043707_0 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 533.0
HKD1_k127_7043707_1 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 434.0
HKD1_k127_7044504_0 Mechanosensitive ion channel K22044 - - 8.492e-207 664.0
HKD1_k127_7044504_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 9.149e-205 643.0
HKD1_k127_7044504_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 445.0
HKD1_k127_7044504_11 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 428.0
HKD1_k127_7044504_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 378.0
HKD1_k127_7044504_13 CYTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 387.0
HKD1_k127_7044504_14 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
HKD1_k127_7044504_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 342.0
HKD1_k127_7044504_16 chorismate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 316.0
HKD1_k127_7044504_17 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 311.0
HKD1_k127_7044504_18 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001087 285.0
HKD1_k127_7044504_19 methionine biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006099 287.0
HKD1_k127_7044504_2 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 595.0
HKD1_k127_7044504_20 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000000000000000000000000000000000000000002465 224.0
HKD1_k127_7044504_21 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000004348 239.0
HKD1_k127_7044504_22 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000001362 183.0
HKD1_k127_7044504_23 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.0000000000000000000000000000000000001154 146.0
HKD1_k127_7044504_24 Transposase DDE domain - - - 0.0000000000000000000000000000000000001336 147.0
HKD1_k127_7044504_25 Phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000000000000003521 137.0
HKD1_k127_7044504_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 572.0
HKD1_k127_7044504_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 537.0
HKD1_k127_7044504_5 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 491.0
HKD1_k127_7044504_6 drug resistance transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 473.0
HKD1_k127_7044504_7 ubiquitin protein ligase binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 476.0
HKD1_k127_7044504_8 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 451.0
HKD1_k127_7044504_9 prephenate dehydrogenase K00220 - 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 452.0
HKD1_k127_7052771_0 glutamine synthetase K01915 - 6.3.1.2 8.941e-233 728.0
HKD1_k127_7052771_1 Sulfatase - - - 6.718e-215 678.0
HKD1_k127_7052771_10 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000003716 180.0
HKD1_k127_7052771_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000001689 113.0
HKD1_k127_7052771_2 belongs to the aldehyde dehydrogenase family - - - 4.605e-213 706.0
HKD1_k127_7052771_3 Beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 515.0
HKD1_k127_7052771_4 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 513.0
HKD1_k127_7052771_5 Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source K01505,K05396 - 3.5.99.7,4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 552.0
HKD1_k127_7052771_6 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 422.0
HKD1_k127_7052771_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
HKD1_k127_7052771_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000276 247.0
HKD1_k127_7052771_9 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000007383 179.0
HKD1_k127_7085878_0 Pyridine nucleotide-disulphide oxidoreductase - - - 2.082e-245 766.0
HKD1_k127_7085878_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 508.0
HKD1_k127_7085878_2 4Fe-4S dicluster domain K00184,K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 453.0
HKD1_k127_7085878_3 DMSO reductase anchor subunit K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 375.0
HKD1_k127_7132189_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 1.15e-285 884.0
HKD1_k127_7132189_1 FAD binding domain - - - 5.26e-233 726.0
HKD1_k127_7132189_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 430.0
HKD1_k127_7132189_3 Belongs to the amidase family K01426 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 373.0
HKD1_k127_7132189_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 325.0
HKD1_k127_7132189_5 Porin subfamily - - - 0.00000000000000000000000000000000000000000000002513 186.0
HKD1_k127_7132189_6 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000001489 177.0
HKD1_k127_713953_0 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 326.0
HKD1_k127_713953_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003296 280.0
HKD1_k127_713953_2 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001359 269.0
HKD1_k127_713953_3 universal stress protein UspA and related nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000002548 218.0
HKD1_k127_713953_4 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.0000000000000000000000000000000000000000234 158.0
HKD1_k127_713953_5 Methyltransferase FkbM domain - - - 0.0000000005568 69.0
HKD1_k127_714410_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 3.547e-276 856.0
HKD1_k127_714410_1 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 535.0
HKD1_k127_714410_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
HKD1_k127_714410_3 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 340.0
HKD1_k127_714410_4 COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
HKD1_k127_714410_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000005202 211.0
HKD1_k127_714410_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003068 201.0
HKD1_k127_7165691_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 4.385e-211 664.0
HKD1_k127_7165691_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 500.0
HKD1_k127_7165691_2 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000007477 238.0
HKD1_k127_7165691_3 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000002345 221.0
HKD1_k127_7165691_4 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000005759 179.0
HKD1_k127_7168265_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1e-322 994.0
HKD1_k127_7168265_1 - - - - 0.000000000000000474 87.0
HKD1_k127_7195041_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.08e-250 798.0
HKD1_k127_7195041_1 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 440.0
HKD1_k127_7195041_2 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 407.0
HKD1_k127_7195041_3 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000007189 195.0
HKD1_k127_7195041_4 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000001265 175.0
HKD1_k127_7195041_5 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0000000000000001402 95.0
HKD1_k127_7216135_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 2.968e-262 818.0
HKD1_k127_7216135_1 ribosomal rna small subunit methyltransferase - - - 4.143e-209 658.0
HKD1_k127_7216135_10 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000004952 220.0
HKD1_k127_7216135_11 AAA domain - - - 0.0000000000000000000000000000000000000000000000003388 181.0
HKD1_k127_7216135_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000285 160.0
HKD1_k127_7216135_13 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000727 103.0
HKD1_k127_7216135_14 Phosphopantetheine attachment site - - - 0.00000000000000000005422 104.0
HKD1_k127_7216135_2 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 511.0
HKD1_k127_7216135_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 458.0
HKD1_k127_7216135_4 Dehydrogenase E1 component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 452.0
HKD1_k127_7216135_5 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
HKD1_k127_7216135_6 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 417.0
HKD1_k127_7216135_7 Membrane protease subunits, stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 319.0
HKD1_k127_7216135_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000005252 269.0
HKD1_k127_7216135_9 Protein of unknown function (DUF3830) - - - 0.000000000000000000000000000000000000000000000000000000000002267 211.0
HKD1_k127_7231009_0 AAA domain - - - 8.868e-285 897.0
HKD1_k127_7231009_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 582.0
HKD1_k127_7231009_10 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000004443 136.0
HKD1_k127_7231009_11 protein histidine kinase activity - - - 0.0000002029 61.0
HKD1_k127_7231009_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 403.0
HKD1_k127_7231009_3 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 376.0
HKD1_k127_7231009_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 357.0
HKD1_k127_7231009_5 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 344.0
HKD1_k127_7231009_6 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003221 267.0
HKD1_k127_7231009_7 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001335 259.0
HKD1_k127_7231009_8 bacterial OsmY and nodulation domain K04065 - - 0.0000000000000000000000000000000000000000000000000000000000000000003966 243.0
HKD1_k127_7231009_9 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000000000005925 162.0
HKD1_k127_7248234_0 DEAD/H associated K03724 - - 0.0 1139.0
HKD1_k127_7248234_1 Polysaccharide biosynthesis protein K13013 - - 2.009e-206 667.0
HKD1_k127_7248234_10 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002072 250.0
HKD1_k127_7248234_11 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851,K13007 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000016 244.0
HKD1_k127_7248234_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004459 228.0
HKD1_k127_7248234_13 Staphylococcal nuclease homologue - - - 0.00000000000000000000000001421 116.0
HKD1_k127_7248234_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 608.0
HKD1_k127_7248234_3 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 593.0
HKD1_k127_7248234_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 504.0
HKD1_k127_7248234_5 Metallo-beta-lactamase superfamily K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 450.0
HKD1_k127_7248234_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 427.0
HKD1_k127_7248234_7 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009233 259.0
HKD1_k127_7248234_8 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000001372 252.0
HKD1_k127_7248234_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000005688 248.0
HKD1_k127_7285075_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1492.0
HKD1_k127_7285075_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 383.0
HKD1_k127_7285075_2 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 364.0
HKD1_k127_7285075_3 COG2030 Acyl dehydratase K17865 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0042620,GO:0042621,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.000000000000000000000000000000000000000000000000000000001265 205.0
HKD1_k127_7285075_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000005964 169.0
HKD1_k127_7285075_5 Protein of unknown function (DUF3035) - - - 0.000000000000000000000000002088 117.0
HKD1_k127_7298313_0 PFAM Rh family protein ammonium transporter K03320 - - 2.406e-213 673.0
HKD1_k127_7298313_1 COG0436 Aspartate tyrosine aromatic aminotransferase K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 567.0
HKD1_k127_7298313_2 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 542.0
HKD1_k127_7298313_3 alpha, beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005275 280.0
HKD1_k127_7298313_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741,K03892 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000001621 244.0
HKD1_k127_7298313_5 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000002692 224.0
HKD1_k127_7298313_6 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008071 219.0
HKD1_k127_7298313_7 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000003924 214.0
HKD1_k127_7298313_8 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000002353 132.0
HKD1_k127_7298313_9 Ftsk_gamma K03466 - - 0.0000000000001129 84.0
HKD1_k127_7299750_0 CoA-binding domain protein K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 619.0
HKD1_k127_7299750_1 imidazolonepropionase activity K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 592.0
HKD1_k127_7299750_2 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 374.0
HKD1_k127_7299750_3 NADH flavin oxidoreductase NADH oxidase K21833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 326.0
HKD1_k127_7299750_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
HKD1_k127_7299750_5 deiminase K05603 - 3.5.3.13 0.0000000000000000000006507 98.0
HKD1_k127_7307912_0 COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 2.133e-287 893.0
HKD1_k127_7307912_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 605.0
HKD1_k127_7307912_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000006711 107.0
HKD1_k127_7307912_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 449.0
HKD1_k127_7307912_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 356.0
HKD1_k127_7307912_4 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006324 271.0
HKD1_k127_7307912_5 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001874 254.0
HKD1_k127_7307912_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007598 262.0
HKD1_k127_7307912_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000001414 229.0
HKD1_k127_7307912_8 Belongs to the BolA IbaG family K05527,K22066 - - 0.0000000000000000000000000007236 118.0
HKD1_k127_7307912_9 Ribbon-helix-helix domain - - - 0.000000000000000000000000002716 114.0
HKD1_k127_7396780_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1328.0
HKD1_k127_7396780_1 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 485.0
HKD1_k127_7396780_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 400.0
HKD1_k127_7396780_3 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 353.0
HKD1_k127_7396780_4 PFAM ABC-3 protein K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 325.0
HKD1_k127_7396780_5 abc transporter K02074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 297.0
HKD1_k127_7396780_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000324 170.0
HKD1_k127_7396780_7 protein conserved in bacteria K09796 - - 0.0000000000000000000000000000000000000002483 158.0
HKD1_k127_7396780_8 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000005913 97.0
HKD1_k127_7396780_9 propionyl-CoA carboxylase K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.000000000000001242 76.0
HKD1_k127_7430367_0 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101 - 1.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 526.0
HKD1_k127_7430367_1 FAD binding domain K10676 - 1.14.13.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 472.0
HKD1_k127_7430367_2 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 453.0
HKD1_k127_7430367_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 399.0
HKD1_k127_7433431_0 III protein, CoA-transferase family - - - 8.487e-212 665.0
HKD1_k127_7433431_1 FMN-dependent dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 498.0
HKD1_k127_7433431_10 Putative peptidoglycan binding domain - - - 0.00000000001205 72.0
HKD1_k127_7433431_2 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 365.0
HKD1_k127_7433431_3 belongs to the nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
HKD1_k127_7433431_4 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 359.0
HKD1_k127_7433431_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 314.0
HKD1_k127_7433431_6 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 311.0
HKD1_k127_7433431_7 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000003561 195.0
HKD1_k127_7433431_8 - - - - 0.000000000000007212 81.0
HKD1_k127_7433431_9 COG0457 FOG TPR repeat - - - 0.0000000000001519 71.0
HKD1_k127_7507356_0 homoserine dehydrogenase - - - 5.147e-197 646.0
HKD1_k127_7507356_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 585.0
HKD1_k127_7507356_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000002467 185.0
HKD1_k127_7507356_11 Major facilitator Superfamily K08195 - - 0.000000000000002858 78.0
HKD1_k127_7507356_2 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 348.0
HKD1_k127_7507356_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 329.0
HKD1_k127_7507356_4 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 300.0
HKD1_k127_7507356_5 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003061 282.0
HKD1_k127_7507356_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000962 279.0
HKD1_k127_7507356_7 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000742 243.0
HKD1_k127_7507356_8 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000454 234.0
HKD1_k127_7507356_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000003863 198.0
HKD1_k127_751566_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 555.0
HKD1_k127_751566_1 GDP-mannose 4,6 dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 405.0
HKD1_k127_751566_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
HKD1_k127_751566_3 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
HKD1_k127_751566_4 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000000000000000005386 198.0
HKD1_k127_751566_5 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.0000000000000000002179 101.0
HKD1_k127_7521716_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1215.0
HKD1_k127_7521716_1 GAF domain - - - 1.474e-209 676.0
HKD1_k127_7521716_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 460.0
HKD1_k127_7521716_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000002146 189.0
HKD1_k127_7521716_4 Protein of unknown function (DUF2778) - - - 0.0000000000000000000000000000000001716 136.0
HKD1_k127_7521716_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000004887 117.0
HKD1_k127_7521716_6 - - - - 0.0000002119 61.0
HKD1_k127_7559297_0 MMPL family K07003 - - 2.157e-288 910.0
HKD1_k127_7559297_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 565.0
HKD1_k127_7559297_2 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 467.0
HKD1_k127_7559297_3 Amino acid permease K03756,K03759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 370.0
HKD1_k127_7559297_4 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007116 269.0
HKD1_k127_7559297_5 Arginine K01478 - 3.5.3.6 0.0000000000000000000000000000000000146 137.0
HKD1_k127_7559297_6 Arginine K01478 - 3.5.3.6 0.0000000000000000000000000000000271 125.0
HKD1_k127_7559297_7 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000007639 127.0
HKD1_k127_7561836_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 4.271e-244 759.0
HKD1_k127_7561836_1 the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 501.0
HKD1_k127_7561836_2 Belongs to the protein N5-glutamine methyltransferase family K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 424.0
HKD1_k127_7561836_3 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 333.0
HKD1_k127_7561836_4 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000005506 192.0
HKD1_k127_7561836_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000002543 107.0
HKD1_k127_7562359_0 Sulfatase K01130 - 3.1.6.1 0.0 1530.0
HKD1_k127_7562359_1 Cytochrome c554 and c-prime - - - 3.168e-320 1011.0
HKD1_k127_7562359_2 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 591.0
HKD1_k127_7562359_3 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000446 271.0
HKD1_k127_7562359_4 Ion channel - - - 0.00000000000000000000000000000000001125 156.0
HKD1_k127_7562359_5 Glycine-zipper domain - - - 0.0000000000000000000000000001005 123.0
HKD1_k127_7562359_6 long-chain fatty acid transport protein - - - 0.000000000000000000000001782 113.0
HKD1_k127_7562359_7 - - - - 0.00000361 53.0
HKD1_k127_7562359_8 Amidase K01426 - 3.5.1.4 0.000007434 53.0
HKD1_k127_7563619_0 Belongs to the GARS family K01945 - 6.3.4.13 3.401e-201 634.0
HKD1_k127_7563619_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 553.0
HKD1_k127_7563619_2 3-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 489.0
HKD1_k127_7563619_3 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 380.0
HKD1_k127_7563619_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 349.0
HKD1_k127_7563619_5 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 337.0
HKD1_k127_7563619_6 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000645 289.0
HKD1_k127_7563619_7 protein conserved in bacteria K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000008768 241.0
HKD1_k127_7563619_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000003084 223.0
HKD1_k127_7595002_0 helix_turn_helix isocitrate lyase regulation K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006903 277.0
HKD1_k127_7595002_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002258 275.0
HKD1_k127_7595002_2 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002907 264.0
HKD1_k127_7595002_3 Class II aldolase K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000001626 268.0
HKD1_k127_7595002_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000002138 154.0
HKD1_k127_7606974_0 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 509.0
HKD1_k127_7606974_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 428.0
HKD1_k127_7606974_10 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000004619 145.0
HKD1_k127_7606974_11 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.000000000000000000000000000001147 127.0
HKD1_k127_7606974_12 transcriptional regulator, ArsR family - - - 0.00000000000000000000001008 102.0
HKD1_k127_7606974_13 TraX protein - - - 0.000000000000001717 86.0
HKD1_k127_7606974_14 WD40 repeats K20332 - - 0.000000000001411 81.0
HKD1_k127_7606974_15 PAS domain - - - 0.0000000001235 70.0
HKD1_k127_7606974_16 determination of stomach left/right asymmetry - - - 0.0002155 54.0
HKD1_k127_7606974_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 438.0
HKD1_k127_7606974_3 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 359.0
HKD1_k127_7606974_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 325.0
HKD1_k127_7606974_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
HKD1_k127_7606974_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008605 244.0
HKD1_k127_7606974_7 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000000000000000004121 196.0
HKD1_k127_7606974_8 Avidin family - - - 0.00000000000000000000000000000000000000000000002515 174.0
HKD1_k127_7606974_9 - - - - 0.0000000000000000000000000000000000002438 157.0
HKD1_k127_7617107_0 Aerotolerance regulator N-terminal - - - 0.0 1155.0
HKD1_k127_7617107_1 membrane - - - 0.0 1036.0
HKD1_k127_7617107_10 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000000000000000000000000000000005046 210.0
HKD1_k127_7617107_11 TRANSCRIPTIONal - - - 0.000000000000000000000000000001032 130.0
HKD1_k127_7617107_12 Iron/manganese superoxide dismutases, C-terminal domain - - - 0.000000000000001145 78.0
HKD1_k127_7617107_13 - - - - 0.000000001023 64.0
HKD1_k127_7617107_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 531.0
HKD1_k127_7617107_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 481.0
HKD1_k127_7617107_4 poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 447.0
HKD1_k127_7617107_5 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 383.0
HKD1_k127_7617107_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 390.0
HKD1_k127_7617107_7 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K19743 - 1.4.1.1,1.5.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 323.0
HKD1_k127_7617107_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001255 269.0
HKD1_k127_7617107_9 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009527 224.0
HKD1_k127_7619003_0 Hydrolase CocE NonD family K06978 - - 1.263e-253 789.0
HKD1_k127_7619003_1 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 573.0
HKD1_k127_7619003_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 378.0
HKD1_k127_7619003_3 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 288.0
HKD1_k127_7619003_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004243 284.0
HKD1_k127_7619003_5 Glcg protein - - - 0.00000000000000000000000000000000000000000000000000001716 192.0
HKD1_k127_7619003_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000008885 204.0
HKD1_k127_7619003_7 - - - - 0.000000000000000000000000000000000000002927 156.0
HKD1_k127_762588_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 7.804e-236 743.0
HKD1_k127_762588_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 588.0
HKD1_k127_762588_10 SnoaL-like domain - - - 0.00000000000000000000000000000000000000001585 160.0
HKD1_k127_762588_11 NIPSNAP - - - 0.000000000000000000000000000000000000001444 150.0
HKD1_k127_762588_12 Cupredoxin-like domain - - - 0.00000000000000000000000000000000000003266 149.0
HKD1_k127_762588_2 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 590.0
HKD1_k127_762588_3 PFAM Acetamidase Formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 575.0
HKD1_k127_762588_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 440.0
HKD1_k127_762588_5 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K11707 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 326.0
HKD1_k127_762588_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 299.0
HKD1_k127_762588_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005715 267.0
HKD1_k127_762588_8 Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001461 237.0
HKD1_k127_762588_9 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000009325 172.0
HKD1_k127_7632249_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 553.0
HKD1_k127_7632249_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 486.0
HKD1_k127_7632249_10 YCII-related domain K09780 - - 0.000000000006365 78.0
HKD1_k127_7632249_11 Membrane-associated sensor, integral membrane domain - - - 0.0001907 45.0
HKD1_k127_7632249_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 441.0
HKD1_k127_7632249_3 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 404.0
HKD1_k127_7632249_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 292.0
HKD1_k127_7632249_5 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004468 272.0
HKD1_k127_7632249_6 isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005439 286.0
HKD1_k127_7632249_7 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002802 270.0
HKD1_k127_7632249_8 Transcriptional regulatory protein, C terminal K14981 - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
HKD1_k127_7632249_9 - - - - 0.00000000000000000000000000009352 127.0
HKD1_k127_7693840_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 331.0
HKD1_k127_7693840_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 325.0
HKD1_k127_7693840_2 PFAM Dimethylmenaquinone methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 306.0
HKD1_k127_7693840_3 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000002198 198.0
HKD1_k127_7693840_4 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000006002 181.0
HKD1_k127_7693840_5 Polymer-forming cytoskeletal - - - 0.0000000000001904 82.0
HKD1_k127_7705393_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 508.0
HKD1_k127_7705393_1 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 422.0
HKD1_k127_7705393_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 395.0
HKD1_k127_7705393_3 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000004908 172.0
HKD1_k127_7705393_4 Chromate transporter K07240 - - 0.00000000000000000000000000000000000002125 158.0
HKD1_k127_7705393_5 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000001085 126.0
HKD1_k127_7719050_0 Aldehyde dehydrogenase family - - - 2.701e-223 702.0
HKD1_k127_7719050_1 Aminotransferase - - - 1.542e-222 694.0
HKD1_k127_7719050_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 454.0
HKD1_k127_7719050_3 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 270.0
HKD1_k127_7719050_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008407 239.0
HKD1_k127_7719050_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.000000000000000000000000000000000000000000000000009145 192.0
HKD1_k127_7719050_6 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.00000000000000000000000000000000000000006781 158.0
HKD1_k127_776225_0 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 458.0
HKD1_k127_776225_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 392.0
HKD1_k127_776225_10 OmpA MotB K02557 - - 0.000000000000000007157 93.0
HKD1_k127_776225_11 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000004993 57.0
HKD1_k127_776225_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 327.0
HKD1_k127_776225_3 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 313.0
HKD1_k127_776225_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001256 297.0
HKD1_k127_776225_5 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000002467 233.0
HKD1_k127_776225_6 Glycosyl-transferase family 4 - - - 0.0000000000000000000000000000000000000000000003654 177.0
HKD1_k127_776225_7 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000001029 169.0
HKD1_k127_776225_8 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000001734 140.0
HKD1_k127_776225_9 Domain of unknown function (DUF1330) - - - 0.0000000000000000000004135 103.0
HKD1_k127_7799639_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1139.0
HKD1_k127_7799639_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.908e-199 633.0
HKD1_k127_7799639_10 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000003171 210.0
HKD1_k127_7799639_11 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000002882 170.0
HKD1_k127_7799639_12 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000005296 108.0
HKD1_k127_7799639_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
HKD1_k127_7799639_3 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 466.0
HKD1_k127_7799639_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 407.0
HKD1_k127_7799639_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000882 267.0
HKD1_k127_7799639_6 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004746 266.0
HKD1_k127_7799639_7 COG0593 ATPase involved in DNA replication initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000003182 252.0
HKD1_k127_7799639_8 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000000000000005122 230.0
HKD1_k127_7799639_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000002767 231.0
HKD1_k127_7897218_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.382e-289 904.0
HKD1_k127_7897218_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 315.0
HKD1_k127_7897218_2 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000006898 250.0
HKD1_k127_7897516_0 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 546.0
HKD1_k127_7897516_1 acid transport system permease K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 530.0
HKD1_k127_7897516_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 505.0
HKD1_k127_7897516_3 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 497.0
HKD1_k127_7897516_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 352.0
HKD1_k127_7915169_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 1.158e-239 751.0
HKD1_k127_7915169_1 Flavin-binding monooxygenase-like - - - 1.224e-229 722.0
HKD1_k127_7915169_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 522.0
HKD1_k127_7915169_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 484.0
HKD1_k127_7915169_4 COG0656 Aldo keto reductases, related to diketogulonate reductase K06222 - 1.1.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 319.0
HKD1_k127_7959308_0 ABC-type Fe3 transport system permease component K02011 - - 2.603e-283 892.0
HKD1_k127_7959308_1 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 576.0
HKD1_k127_7959308_10 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 326.0
HKD1_k127_7959308_11 PFAM Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 297.0
HKD1_k127_7959308_12 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003061 282.0
HKD1_k127_7959308_13 Subtilase family K12685 - - 0.0000000000000000000000000000000000000000000000000000000000000000001832 258.0
HKD1_k127_7959308_14 Nitroreductase family - GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000009217 166.0
HKD1_k127_7959308_15 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000001351 106.0
HKD1_k127_7959308_16 SEC-C motif - - - 0.0000000000000001981 84.0
HKD1_k127_7959308_2 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 548.0
HKD1_k127_7959308_3 Bacterial extracellular solute-binding protein K02012,K11081 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 534.0
HKD1_k127_7959308_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 475.0
HKD1_k127_7959308_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 439.0
HKD1_k127_7959308_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 445.0
HKD1_k127_7959308_7 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 424.0
HKD1_k127_7959308_8 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 349.0
HKD1_k127_7959308_9 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 346.0
HKD1_k127_7964205_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 6.983e-318 982.0
HKD1_k127_7964205_1 single-stranded-DNA-specific exonuclease recJ K07462 - - 2.373e-239 754.0
HKD1_k127_7964205_10 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000005788 210.0
HKD1_k127_7964205_11 OmpA family - - - 0.0000000000225 76.0
HKD1_k127_7964205_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000217 58.0
HKD1_k127_7964205_13 - - - - 0.00000003371 58.0
HKD1_k127_7964205_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000209 54.0
HKD1_k127_7964205_15 chlorophyll binding - - - 0.000005713 58.0
HKD1_k127_7964205_2 homoserine dehydrogenase K00003 - 1.1.1.3 4.223e-197 623.0
HKD1_k127_7964205_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 541.0
HKD1_k127_7964205_4 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 538.0
HKD1_k127_7964205_5 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 439.0
HKD1_k127_7964205_6 Acyl-transferase K00655,K01897 - 2.3.1.51,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000006739 273.0
HKD1_k127_7964205_7 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000004777 235.0
HKD1_k127_7964205_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000001564 204.0
HKD1_k127_7964205_9 Acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000006766 205.0
HKD1_k127_7982676_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.058e-319 987.0
HKD1_k127_7982676_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 467.0
HKD1_k127_7982676_2 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 457.0
HKD1_k127_7982676_3 transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000001477 250.0
HKD1_k127_7982676_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000003548 116.0
HKD1_k127_7982676_5 Oxidoreductase K19746 - 1.4.99.6 0.00000000000000000001551 92.0
HKD1_k127_8001564_0 Histidine kinase K07646 - 2.7.13.3 0.0 1193.0
HKD1_k127_8001564_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1108.0
HKD1_k127_8001564_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 368.0
HKD1_k127_8001564_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 354.0
HKD1_k127_8001564_12 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 312.0
HKD1_k127_8001564_13 Formate/nitrite transporter K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004468 283.0
HKD1_k127_8001564_14 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002583 275.0
HKD1_k127_8001564_15 Protein of unknown function (DUF3376) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001518 280.0
HKD1_k127_8001564_16 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000001407 234.0
HKD1_k127_8001564_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000007031 172.0
HKD1_k127_8001564_18 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.0000000000000000000000000000000006907 135.0
HKD1_k127_8001564_19 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000003208 124.0
HKD1_k127_8001564_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 8.288e-294 909.0
HKD1_k127_8001564_20 Cytochrome c K08738 - - 0.00000000000000000003918 106.0
HKD1_k127_8001564_22 - - - - 0.00007035 49.0
HKD1_k127_8001564_23 - - - - 0.0000924 48.0
HKD1_k127_8001564_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.732e-258 809.0
HKD1_k127_8001564_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.959e-223 704.0
HKD1_k127_8001564_5 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 580.0
HKD1_k127_8001564_6 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 558.0
HKD1_k127_8001564_7 asparaginase K01444 - 3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 549.0
HKD1_k127_8001564_8 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 454.0
HKD1_k127_8001564_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 417.0
HKD1_k127_8020460_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 522.0
HKD1_k127_8020460_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 406.0
HKD1_k127_8020460_2 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 308.0
HKD1_k127_8020460_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000001154 226.0
HKD1_k127_8020460_4 DUF218 domain - - - 0.00000000000000000001075 93.0
HKD1_k127_8020460_5 energy transducer activity K03832 - - 0.0000344 48.0
HKD1_k127_8034952_0 L-lactate permease K03303 - - 7.925e-285 883.0
HKD1_k127_8034952_1 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 581.0
HKD1_k127_8034952_2 lysyl-tRNA synthetase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 488.0
HKD1_k127_8034952_3 Cytochrome c2 K08738 - - 0.000000000000000000000000000002516 125.0
HKD1_k127_8034952_4 Hemerythrin HHE cation binding K07322 - - 0.00000000000000000000001817 108.0
HKD1_k127_8034952_5 - - - - 0.000000000003527 70.0
HKD1_k127_834213_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.283e-301 933.0
HKD1_k127_834213_1 Hydantoinase/oxoprolinase N-terminal region - - - 8.782e-235 734.0
HKD1_k127_834213_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 503.0
HKD1_k127_834213_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 397.0
HKD1_k127_834213_4 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000175 207.0
HKD1_k127_839633_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.04e-229 719.0
HKD1_k127_839633_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 609.0
HKD1_k127_839633_10 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000003397 105.0
HKD1_k127_839633_11 YGGT family K02221 - - 0.000000000000000000000004926 104.0
HKD1_k127_839633_12 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000003767 101.0
HKD1_k127_839633_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 388.0
HKD1_k127_839633_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 357.0
HKD1_k127_839633_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 302.0
HKD1_k127_839633_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001156 260.0
HKD1_k127_839633_6 invasion associated locus B - - - 0.00000000000000000000000000000000000000000000000000004069 192.0
HKD1_k127_839633_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000009914 186.0
HKD1_k127_839633_8 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000001063 173.0
HKD1_k127_839633_9 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000006055 156.0
HKD1_k127_83997_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 472.0
HKD1_k127_83997_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
HKD1_k127_83997_2 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000003703 231.0
HKD1_k127_83997_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003188 223.0
HKD1_k127_83997_4 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000000000000000005987 177.0
HKD1_k127_83997_5 Sterol carrier protein - - - 0.000000000000000000000000000021 123.0
HKD1_k127_83997_6 - - - - 0.00000000000000000000000000005473 120.0
HKD1_k127_83997_7 TadE-like protein - - - 0.0000000000000000000000000006212 120.0
HKD1_k127_83997_8 TadE-like protein - - - 0.0000000005577 70.0
HKD1_k127_83997_9 Cytochrome c - - - 0.0000000008315 69.0
HKD1_k127_883501_0 Binding-protein-dependent transport system inner membrane component K02050 - - 4.51e-238 750.0
HKD1_k127_883501_1 tRNA synthetases class II (D, K and N) - - - 6.191e-227 717.0
HKD1_k127_883501_10 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
HKD1_k127_883501_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000007272 189.0
HKD1_k127_883501_12 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000002632 161.0
HKD1_k127_883501_13 ABC transporter K15555 - - 0.000000000000000000000000000000000000462 146.0
HKD1_k127_883501_14 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000001444 147.0
HKD1_k127_883501_15 Cache_2 - - - 0.00000000000000000000000000000000004228 141.0
HKD1_k127_883501_16 SCP-2 sterol transfer family - - - 0.00000000000000000000000000915 113.0
HKD1_k127_883501_17 chlorophyll binding - - - 0.000000002409 67.0
HKD1_k127_883501_18 - - - - 0.0000008618 59.0
HKD1_k127_883501_2 C-terminal AAA-associated domain K02049 - - 2.008e-200 633.0
HKD1_k127_883501_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 544.0
HKD1_k127_883501_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
HKD1_k127_883501_5 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 376.0
HKD1_k127_883501_6 Sulfotransferase family K13472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 365.0
HKD1_k127_883501_7 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 373.0
HKD1_k127_883501_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 325.0
HKD1_k127_883501_9 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000234 275.0
HKD1_k127_887121_0 Alpha-2-Macroglobulin K06894 - - 3.937e-232 747.0
HKD1_k127_887121_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 576.0
HKD1_k127_90045_0 - - - - 0.0 1019.0
HKD1_k127_90045_1 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 542.0
HKD1_k127_90045_2 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 516.0
HKD1_k127_90045_3 Catechol dioxygenase N terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 320.0
HKD1_k127_90045_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 321.0
HKD1_k127_90045_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000004836 212.0
HKD1_k127_90045_6 - - - - 0.000000000000000001621 87.0
HKD1_k127_905201_0 Required for chromosome condensation and partitioning K03529 - - 5.711e-241 767.0
HKD1_k127_905201_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 6.03e-233 728.0
HKD1_k127_905201_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 591.0
HKD1_k127_905201_3 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 361.0
HKD1_k127_905201_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 319.0
HKD1_k127_905201_5 Fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000005917 174.0
HKD1_k127_905201_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000009991 166.0
HKD1_k127_905201_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000001632 140.0
HKD1_k127_905201_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000002814 107.0
HKD1_k127_905201_9 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000000000004705 104.0
HKD1_k127_912707_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 434.0
HKD1_k127_912707_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002155 256.0
HKD1_k127_912707_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000008798 165.0
HKD1_k127_912707_3 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000001622 154.0
HKD1_k127_912707_4 Pfam Amidohydrolase K07045 - - 0.000000000000000000000000000000000001451 154.0
HKD1_k127_928331_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 510.0
HKD1_k127_928331_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004404 271.0
HKD1_k127_928331_2 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000338 224.0
HKD1_k127_928331_3 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000001066 203.0
HKD1_k127_928331_4 PFAM transglutaminase family protein cysteine peptidase BTLCP - - - 0.00000000000000000000000000000000000000000004194 169.0
HKD1_k127_928331_5 Cytochrome c-type biogenesis protein K02200 - - 0.0000002076 56.0
HKD1_k127_931005_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.318e-283 893.0
HKD1_k127_931005_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 2.639e-197 621.0
HKD1_k127_931005_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 461.0
HKD1_k127_931005_3 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000000001156 243.0
HKD1_k127_931005_4 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000006653 137.0
HKD1_k127_931005_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000001636 79.0
HKD1_k127_95094_0 Elongation factor SelB, winged helix K03833 - - 1.77e-230 738.0
HKD1_k127_95094_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 602.0
HKD1_k127_95094_2 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 355.0
HKD1_k127_95094_3 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 325.0
HKD1_k127_95094_4 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000001012 231.0
HKD1_k127_986318_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.797e-216 686.0
HKD1_k127_986318_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 553.0
HKD1_k127_986318_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000005416 141.0
HKD1_k127_986318_11 Exopolysaccharide synthesis ExoD - - - 0.000000000000000000000000000000007517 142.0
HKD1_k127_986318_12 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000002977 112.0
HKD1_k127_986318_13 - - - - 0.0009448 50.0
HKD1_k127_986318_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 454.0
HKD1_k127_986318_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 438.0
HKD1_k127_986318_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 402.0
HKD1_k127_986318_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 353.0
HKD1_k127_986318_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004652 289.0
HKD1_k127_986318_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004399 270.0
HKD1_k127_986318_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000196 231.0
HKD1_k127_986318_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000479 185.0
HKD1_k127_986355_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1366.0
HKD1_k127_986355_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000047 126.0
HKD1_k127_993109_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.554e-238 754.0
HKD1_k127_993109_1 Cysteine-rich domain - - - 1.14e-223 708.0
HKD1_k127_993109_10 - - - - 0.0000000000000000000008859 99.0
HKD1_k127_993109_11 Plasmid stabilization system - - - 0.00000000003635 64.0
HKD1_k127_993109_12 Plasmid stabilization system - - - 0.00000003876 55.0
HKD1_k127_993109_2 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 421.0
HKD1_k127_993109_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 295.0
HKD1_k127_993109_4 COG1592 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003574 266.0
HKD1_k127_993109_5 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000004948 239.0
HKD1_k127_993109_6 transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000002046 228.0
HKD1_k127_993109_7 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000000000000002004 209.0
HKD1_k127_993109_8 protein conserved in bacteria K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000007826 194.0
HKD1_k127_993109_9 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000003746 203.0
HKD1_k127_99362_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 2.139e-230 741.0
HKD1_k127_99362_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 566.0
HKD1_k127_99362_2 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 447.0
HKD1_k127_99362_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 404.0
HKD1_k127_996919_0 2-dehydropantoate 2-reductase activity K00077,K01295 - 1.1.1.169,3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 421.0
HKD1_k127_996919_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 338.0
HKD1_k127_996919_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000004361 103.0
HKD1_k127_996919_3 Short-chain dehydrogenase reductase sdr - - - 0.0000000000008661 71.0