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Overview

ID MAG01756
Name HKD1_bin.76
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Casimicrobiaceae
Genus VBCG01
Species
Assembly information
Completeness (%) 69.38
Contamination (%) 1.92
GC content (%) 70.0
N50 (bp) 22,056
Genome size (bp) 2,840,134

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2671

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1024383_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.207e-200 636.0
HKD1_k127_1024383_1 ABC-type sugar transport system periplasmic component K02027,K05813 - - 3.574e-200 649.0
HKD1_k127_1024383_10 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 312.0
HKD1_k127_1024383_11 anthranilate K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 287.0
HKD1_k127_1024383_12 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000001448 257.0
HKD1_k127_1024383_13 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000009839 203.0
HKD1_k127_1024383_14 ApaG domain - - - 0.00000000000000000000000000000000000000000000000000002667 190.0
HKD1_k127_1024383_15 Conserved protein of DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000002536 179.0
HKD1_k127_1024383_16 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000002065 120.0
HKD1_k127_1024383_17 D-amino acid K00285 - 1.4.5.1 0.00000000000000000000000000007789 115.0
HKD1_k127_1024383_18 - - - - 0.00000000000000000000004635 116.0
HKD1_k127_1024383_19 LPXTG-motif cell wall anchor domain - - - 0.000009841 58.0
HKD1_k127_1024383_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 519.0
HKD1_k127_1024383_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 503.0
HKD1_k127_1024383_4 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 439.0
HKD1_k127_1024383_5 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 449.0
HKD1_k127_1024383_6 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 428.0
HKD1_k127_1024383_7 Membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 422.0
HKD1_k127_1024383_8 Aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 375.0
HKD1_k127_1024383_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 356.0
HKD1_k127_1036141_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 409.0
HKD1_k127_1036141_1 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000004745 169.0
HKD1_k127_1036141_2 Phosphotransferase System K11189 - - 0.000000000000000000000000000000001131 134.0
HKD1_k127_1036141_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000138 78.0
HKD1_k127_1037671_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1677.0
HKD1_k127_1037671_1 Methylmalonyl-CoA mutase K01848 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.2 3.159e-234 738.0
HKD1_k127_1037671_10 PFAM PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 338.0
HKD1_k127_1037671_11 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 316.0
HKD1_k127_1037671_12 Binding-protein-dependent transport system inner membrane component K10002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 314.0
HKD1_k127_1037671_13 Phenylacetic acid degradation protein PaaY K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 292.0
HKD1_k127_1037671_14 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 287.0
HKD1_k127_1037671_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000231 281.0
HKD1_k127_1037671_16 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 286.0
HKD1_k127_1037671_17 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001186 258.0
HKD1_k127_1037671_18 Aldolase K01631 - 4.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
HKD1_k127_1037671_19 PFAM 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000008776 248.0
HKD1_k127_1037671_2 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 2.767e-202 645.0
HKD1_k127_1037671_20 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000004637 233.0
HKD1_k127_1037671_21 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000005184 208.0
HKD1_k127_1037671_22 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.0000000000000000000000000000000000000000000000001226 181.0
HKD1_k127_1037671_23 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000001764 183.0
HKD1_k127_1037671_24 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000004272 152.0
HKD1_k127_1037671_25 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000000275 132.0
HKD1_k127_1037671_26 SnoaL-like domain - - - 0.000000000000000000000002171 106.0
HKD1_k127_1037671_27 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000009766 86.0
HKD1_k127_1037671_29 OmpA family - - - 0.0000004302 60.0
HKD1_k127_1037671_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.396e-196 627.0
HKD1_k127_1037671_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 565.0
HKD1_k127_1037671_5 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 521.0
HKD1_k127_1037671_6 NADPH quinone K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 436.0
HKD1_k127_1037671_7 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 454.0
HKD1_k127_1037671_8 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 422.0
HKD1_k127_1037671_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 383.0
HKD1_k127_1038514_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 614.0
HKD1_k127_1038514_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000003524 254.0
HKD1_k127_1038514_2 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000001242 172.0
HKD1_k127_1038514_3 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000002372 164.0
HKD1_k127_1038514_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000005236 103.0
HKD1_k127_1058894_0 PQQ enzyme repeat - - - 9.512e-295 913.0
HKD1_k127_1058894_1 TonB dependent receptor K02014 - - 5.207e-198 644.0
HKD1_k127_1058894_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000002105 252.0
HKD1_k127_1058894_11 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000002959 247.0
HKD1_k127_1058894_12 4Fe-4S dicluster domain K05796 - - 0.00000000000000000000000000000000000000000000000000000000003781 209.0
HKD1_k127_1058894_13 Ankyrin repeats (3 copies) K06867,K21440 - - 0.000000000000000000000000000000000000000000000000000000008931 205.0
HKD1_k127_1058894_14 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000002601 205.0
HKD1_k127_1058894_15 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000391 158.0
HKD1_k127_1058894_16 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000001495 133.0
HKD1_k127_1058894_17 - - - - 0.00000000000000000003176 94.0
HKD1_k127_1058894_2 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 463.0
HKD1_k127_1058894_3 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 423.0
HKD1_k127_1058894_4 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 422.0
HKD1_k127_1058894_5 abc transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 394.0
HKD1_k127_1058894_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 403.0
HKD1_k127_1058894_7 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 386.0
HKD1_k127_1058894_8 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 347.0
HKD1_k127_1058894_9 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 345.0
HKD1_k127_1059440_0 Transcriptional regulator crp fnr family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 296.0
HKD1_k127_1059440_1 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000001366 186.0
HKD1_k127_1059440_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000005059 156.0
HKD1_k127_1059440_3 - - - - 0.0000000000000000000000000000001251 138.0
HKD1_k127_1064725_0 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 7.77e-237 753.0
HKD1_k127_1064725_1 PFAM NADH dehydrogenase (ubiquinone) 30 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 593.0
HKD1_k127_1064725_2 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 452.0
HKD1_k127_1064725_3 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 301.0
HKD1_k127_1064725_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000112 263.0
HKD1_k127_1064725_5 Proton-conducting membrane transporter - - - 0.000000000000000000000000001238 113.0
HKD1_k127_1074714_0 ATPase (P-type) K01535 - 3.6.3.6 1.36e-304 953.0
HKD1_k127_1074714_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000006147 181.0
HKD1_k127_1080579_0 ABC transporter K06020 - 3.6.3.25 4.713e-315 970.0
HKD1_k127_1080579_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.568e-230 729.0
HKD1_k127_1080579_10 mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000005622 251.0
HKD1_k127_1080579_11 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000002093 168.0
HKD1_k127_1080579_12 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000002701 135.0
HKD1_k127_1080579_13 Domain of unknown function (DUF4124) - - - 0.0000000000000000007618 96.0
HKD1_k127_1080579_14 PTS HPr component phosphorylation site - - - 0.0000000000000001071 85.0
HKD1_k127_1080579_2 ABC transporter K06158 - - 1.246e-214 685.0
HKD1_k127_1080579_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 4.914e-211 674.0
HKD1_k127_1080579_4 AmpG muropeptide MFS transporter K08218 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 595.0
HKD1_k127_1080579_5 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 402.0
HKD1_k127_1080579_6 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 352.0
HKD1_k127_1080579_7 Transcriptional regulator, LysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 305.0
HKD1_k127_1080579_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 293.0
HKD1_k127_1080579_9 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002197 232.0
HKD1_k127_1085055_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 434.0
HKD1_k127_1085055_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 383.0
HKD1_k127_1103632_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 427.0
HKD1_k127_1103632_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 398.0
HKD1_k127_1103632_2 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 412.0
HKD1_k127_1103632_3 YHS domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001234 261.0
HKD1_k127_1103632_4 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000001159 142.0
HKD1_k127_1103632_5 - - - - 0.00000000000000000000000000000002736 142.0
HKD1_k127_1103632_6 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000003748 85.0
HKD1_k127_1109149_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1471.0
HKD1_k127_1109149_1 Amidohydrolase K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 429.0
HKD1_k127_1109149_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 391.0
HKD1_k127_1109149_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 286.0
HKD1_k127_111164_0 carboxylase K01969 - 6.4.1.4 5.817e-283 879.0
HKD1_k127_111164_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 6.695e-255 819.0
HKD1_k127_111164_10 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 316.0
HKD1_k127_111164_11 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 301.0
HKD1_k127_111164_12 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001352 296.0
HKD1_k127_111164_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005037 256.0
HKD1_k127_111164_14 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
HKD1_k127_111164_15 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000009386 218.0
HKD1_k127_111164_16 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000006401 214.0
HKD1_k127_111164_17 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000007404 186.0
HKD1_k127_111164_18 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000006253 178.0
HKD1_k127_111164_19 - - - - 0.000000000000000000000000000000000000000007115 179.0
HKD1_k127_111164_2 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 8.808e-244 770.0
HKD1_k127_111164_20 transcriptional - - - 0.0000000000000000000000000000000327 137.0
HKD1_k127_111164_21 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000003445 119.0
HKD1_k127_111164_22 protein conserved in bacteria K09984 - - 0.0000000000000000000001206 98.0
HKD1_k127_111164_23 Glycine zipper 2TM domain - - - 0.000000000000000000001409 98.0
HKD1_k127_111164_24 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000007366 79.0
HKD1_k127_111164_25 Glyoxalase-like domain - - - 0.0000000000003724 80.0
HKD1_k127_111164_3 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 3.974e-206 656.0
HKD1_k127_111164_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 588.0
HKD1_k127_111164_5 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 563.0
HKD1_k127_111164_6 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 453.0
HKD1_k127_111164_7 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 451.0
HKD1_k127_111164_8 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 399.0
HKD1_k127_111164_9 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 370.0
HKD1_k127_1142160_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.105e-288 902.0
HKD1_k127_1142160_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.526e-239 747.0
HKD1_k127_1142160_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 362.0
HKD1_k127_1142160_11 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 347.0
HKD1_k127_1142160_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 322.0
HKD1_k127_1142160_13 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 323.0
HKD1_k127_1142160_14 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 311.0
HKD1_k127_1142160_15 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 310.0
HKD1_k127_1142160_16 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
HKD1_k127_1142160_17 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002513 260.0
HKD1_k127_1142160_18 PFAM Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000000000008934 239.0
HKD1_k127_1142160_19 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000001806 235.0
HKD1_k127_1142160_2 DNA mismatch repair protein, C-terminal domain K03572 - - 8.029e-195 625.0
HKD1_k127_1142160_20 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000001025 171.0
HKD1_k127_1142160_21 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000003161 120.0
HKD1_k127_1142160_22 amine dehydrogenase activity K13730 - - 0.000000000000000000000004839 115.0
HKD1_k127_1142160_23 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000008925 111.0
HKD1_k127_1142160_24 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.0000000000000000001514 103.0
HKD1_k127_1142160_25 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000002939 88.0
HKD1_k127_1142160_26 GGDEF domain - - - 0.000000001191 72.0
HKD1_k127_1142160_27 Isocitrate lyase K01637 - 4.1.3.1 0.0000007245 51.0
HKD1_k127_1142160_29 Entericidin EcnA/B family - - - 0.0005888 46.0
HKD1_k127_1142160_3 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 587.0
HKD1_k127_1142160_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 569.0
HKD1_k127_1142160_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 506.0
HKD1_k127_1142160_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 484.0
HKD1_k127_1142160_7 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 412.0
HKD1_k127_1142160_8 LysM domain K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 435.0
HKD1_k127_1142160_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 370.0
HKD1_k127_1147113_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.72e-220 697.0
HKD1_k127_1147113_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 419.0
HKD1_k127_1147113_10 - - - - 0.00000000000000000185 97.0
HKD1_k127_1147113_2 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 406.0
HKD1_k127_1147113_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 332.0
HKD1_k127_1147113_4 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 334.0
HKD1_k127_1147113_5 cobalamin biosynthetic process K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 318.0
HKD1_k127_1147113_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002154 291.0
HKD1_k127_1147113_7 Psort location Cytoplasmic, score K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000006632 192.0
HKD1_k127_1147113_8 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000001429 154.0
HKD1_k127_1147113_9 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000008784 147.0
HKD1_k127_116357_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 2.354e-222 698.0
HKD1_k127_116357_1 GcpE protein K03526 - 1.17.7.1,1.17.7.3 2.502e-197 625.0
HKD1_k127_116357_10 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 349.0
HKD1_k127_116357_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 344.0
HKD1_k127_116357_12 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 298.0
HKD1_k127_116357_13 TilS substrate binding domain K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 303.0
HKD1_k127_116357_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000004685 242.0
HKD1_k127_116357_15 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000000003151 222.0
HKD1_k127_116357_16 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000004591 223.0
HKD1_k127_116357_17 type 4 pilus biogenesis protein K02656 - - 0.00000000000000000000000000000000000000000000000000001112 200.0
HKD1_k127_116357_18 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000000000004723 159.0
HKD1_k127_116357_19 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000007483 144.0
HKD1_k127_116357_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 597.0
HKD1_k127_116357_20 protein conserved in bacteria K09937 - - 0.0000000000000003635 79.0
HKD1_k127_116357_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 545.0
HKD1_k127_116357_4 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 535.0
HKD1_k127_116357_5 TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 497.0
HKD1_k127_116357_6 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 501.0
HKD1_k127_116357_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 476.0
HKD1_k127_116357_8 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 433.0
HKD1_k127_116357_9 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 357.0
HKD1_k127_1207142_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 492.0
HKD1_k127_1207142_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 479.0
HKD1_k127_1207142_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 287.0
HKD1_k127_1207142_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001065 274.0
HKD1_k127_1207142_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
HKD1_k127_1233674_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 - 6.1.1.4 1.381e-252 789.0
HKD1_k127_1233674_1 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 9.706e-217 680.0
HKD1_k127_1233674_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000002552 199.0
HKD1_k127_1233674_11 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000001407 177.0
HKD1_k127_1233674_12 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000002503 126.0
HKD1_k127_1233674_13 Universal stress protein family - - - 0.000000000000000000000000000003543 137.0
HKD1_k127_1233674_14 Cytochrome c mono- and diheme variants - - - 0.0000000000000002255 79.0
HKD1_k127_1233674_15 Cysteine-rich CWC - - - 0.00000000000001809 76.0
HKD1_k127_1233674_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 452.0
HKD1_k127_1233674_3 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 351.0
HKD1_k127_1233674_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 318.0
HKD1_k127_1233674_5 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 317.0
HKD1_k127_1233674_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 295.0
HKD1_k127_1233674_7 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002126 273.0
HKD1_k127_1233674_8 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001413 264.0
HKD1_k127_1233674_9 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000486 258.0
HKD1_k127_1241661_0 ABC transporter transmembrane region K06147 - - 1.766e-217 685.0
HKD1_k127_1241661_1 Belongs to the peptidase S11 family K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000002331 235.0
HKD1_k127_12745_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1453.0
HKD1_k127_12745_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.412e-223 713.0
HKD1_k127_12745_10 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 361.0
HKD1_k127_12745_11 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
HKD1_k127_12745_12 FAD binding domain K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 312.0
HKD1_k127_12745_13 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 314.0
HKD1_k127_12745_14 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000004872 209.0
HKD1_k127_12745_15 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.000000000000000000000000000000000000003711 153.0
HKD1_k127_12745_16 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000004459 143.0
HKD1_k127_12745_17 Alpha/beta hydrolase family - - - 0.000000000000000000001494 109.0
HKD1_k127_12745_18 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000002208 94.0
HKD1_k127_12745_19 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000001096 93.0
HKD1_k127_12745_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 613.0
HKD1_k127_12745_20 - - - - 0.000000001822 69.0
HKD1_k127_12745_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 546.0
HKD1_k127_12745_4 aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 538.0
HKD1_k127_12745_5 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 456.0
HKD1_k127_12745_6 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 470.0
HKD1_k127_12745_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 402.0
HKD1_k127_12745_8 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 394.0
HKD1_k127_12745_9 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 353.0
HKD1_k127_1276926_0 methionine synthase K00548 - 2.1.1.13 1.899e-242 758.0
HKD1_k127_1276926_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 574.0
HKD1_k127_1276926_10 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000003382 145.0
HKD1_k127_1276926_11 Protein of unknown function (DUF2934) - - - 0.00003125 52.0
HKD1_k127_1276926_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 561.0
HKD1_k127_1276926_3 Aminotransferase K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 564.0
HKD1_k127_1276926_4 Histidine kinase K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 381.0
HKD1_k127_1276926_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
HKD1_k127_1276926_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001872 257.0
HKD1_k127_1276926_7 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004625 240.0
HKD1_k127_1276926_8 2-keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000001732 222.0
HKD1_k127_1276926_9 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000003788 165.0
HKD1_k127_1320632_0 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 517.0
HKD1_k127_1320632_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 403.0
HKD1_k127_1320632_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 323.0
HKD1_k127_1320632_3 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000003837 69.0
HKD1_k127_1338990_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 589.0
HKD1_k127_1338990_1 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 503.0
HKD1_k127_1338990_2 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000007918 145.0
HKD1_k127_1338990_3 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000005069 48.0
HKD1_k127_1345575_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1309.0
HKD1_k127_1345575_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 9.456e-321 990.0
HKD1_k127_1345575_10 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000007918 208.0
HKD1_k127_1345575_11 CRS1_YhbY K07574 - - 0.00000000000000000000000000005952 130.0
HKD1_k127_1345575_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.349e-240 766.0
HKD1_k127_1345575_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 567.0
HKD1_k127_1345575_4 Pterin binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 322.0
HKD1_k127_1345575_5 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 303.0
HKD1_k127_1345575_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 303.0
HKD1_k127_1345575_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 291.0
HKD1_k127_1345575_8 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000001685 256.0
HKD1_k127_1345575_9 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000002331 231.0
HKD1_k127_141597_0 enoyl-CoA hydratase K15513 - 4.1.2.44 7.879e-261 816.0
HKD1_k127_141597_1 type II secretion system protein E K02454,K02504,K02652,K12276 - - 8.825e-260 813.0
HKD1_k127_141597_10 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 305.0
HKD1_k127_141597_11 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 261.0
HKD1_k127_141597_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000833 260.0
HKD1_k127_141597_13 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000458 235.0
HKD1_k127_141597_14 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000034 200.0
HKD1_k127_141597_15 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000001754 205.0
HKD1_k127_141597_16 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000002089 207.0
HKD1_k127_141597_17 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000005152 193.0
HKD1_k127_141597_18 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000008462 153.0
HKD1_k127_141597_19 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000924 159.0
HKD1_k127_141597_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.716e-255 796.0
HKD1_k127_141597_20 PFAM transport-associated - - - 0.000000000000000000000000000000000000434 150.0
HKD1_k127_141597_21 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000005068 126.0
HKD1_k127_141597_22 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000003145 117.0
HKD1_k127_141597_23 RDD family - - - 0.000000000001562 81.0
HKD1_k127_141597_24 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.00006203 56.0
HKD1_k127_141597_25 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0007178 45.0
HKD1_k127_141597_3 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.452e-242 759.0
HKD1_k127_141597_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.354e-209 658.0
HKD1_k127_141597_5 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 609.0
HKD1_k127_141597_6 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 532.0
HKD1_k127_141597_7 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 513.0
HKD1_k127_141597_8 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 452.0
HKD1_k127_141597_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 344.0
HKD1_k127_1473969_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 1.575e-293 914.0
HKD1_k127_1473969_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001028 289.0
HKD1_k127_1473969_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007271 276.0
HKD1_k127_1473969_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000002211 258.0
HKD1_k127_1473969_4 Thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000001015 156.0
HKD1_k127_1490919_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 581.0
HKD1_k127_1490919_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 555.0
HKD1_k127_1490919_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 333.0
HKD1_k127_1490919_3 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009958 276.0
HKD1_k127_1490919_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 284.0
HKD1_k127_1490919_5 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000642 237.0
HKD1_k127_1490919_6 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000003311 174.0
HKD1_k127_1490919_7 - - - - 0.00000000000000000000000000000002436 128.0
HKD1_k127_1490919_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000004602 116.0
HKD1_k127_1490919_9 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000006753 99.0
HKD1_k127_1541256_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1156.0
HKD1_k127_155624_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1515.0
HKD1_k127_155624_1 FAD dependent oxidoreductase - - - 0.0 1098.0
HKD1_k127_155624_10 binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 575.0
HKD1_k127_155624_11 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 557.0
HKD1_k127_155624_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836 - 2.6.1.19,2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 559.0
HKD1_k127_155624_13 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 521.0
HKD1_k127_155624_14 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 490.0
HKD1_k127_155624_15 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 479.0
HKD1_k127_155624_16 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 467.0
HKD1_k127_155624_17 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 458.0
HKD1_k127_155624_18 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 445.0
HKD1_k127_155624_19 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 438.0
HKD1_k127_155624_2 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.444e-244 762.0
HKD1_k127_155624_20 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 411.0
HKD1_k127_155624_21 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 389.0
HKD1_k127_155624_22 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 388.0
HKD1_k127_155624_23 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 353.0
HKD1_k127_155624_24 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 298.0
HKD1_k127_155624_25 binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 310.0
HKD1_k127_155624_26 MASE2 domain K18968 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005575 293.0
HKD1_k127_155624_27 Peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004114 289.0
HKD1_k127_155624_28 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002205 291.0
HKD1_k127_155624_29 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006285 267.0
HKD1_k127_155624_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.341e-223 718.0
HKD1_k127_155624_30 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001308 247.0
HKD1_k127_155624_31 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000004624 255.0
HKD1_k127_155624_32 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000005675 224.0
HKD1_k127_155624_33 Domain of unknown function (DUF4743) - - - 0.000000000000000000000000000000000000000000000000000000000009543 217.0
HKD1_k127_155624_34 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000007078 195.0
HKD1_k127_155624_35 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.000000000000000000000000000000000000000000000009056 180.0
HKD1_k127_155624_36 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000378 179.0
HKD1_k127_155624_37 AAA domain - - - 0.000000002467 70.0
HKD1_k127_155624_4 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 1.883e-215 686.0
HKD1_k127_155624_5 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 610.0
HKD1_k127_155624_6 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 609.0
HKD1_k127_155624_7 phosphonoacetate hydrolase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 582.0
HKD1_k127_155624_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 578.0
HKD1_k127_155624_9 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 570.0
HKD1_k127_1664654_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 3.727e-280 886.0
HKD1_k127_1664654_1 nucleoside-diphosphate sugar epimerase - - - 6.817e-199 634.0
HKD1_k127_1664654_2 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 602.0
HKD1_k127_1664654_3 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 407.0
HKD1_k127_1664654_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 336.0
HKD1_k127_1664654_5 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
HKD1_k127_1664654_6 OHCU decarboxylase K13485 - 4.1.1.97 0.00000000000000000000000000000000000000000000000003123 183.0
HKD1_k127_1664654_7 DnaJ-class molecular chaperone with C-terminal Zn finger domain K03686 - - 0.00000002714 61.0
HKD1_k127_169857_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009281 247.0
HKD1_k127_169857_1 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000005278 169.0
HKD1_k127_169857_2 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000000000000000005453 154.0
HKD1_k127_169857_3 Sulfate transporter antisigma-factor antagonist STAS - - - 0.000005945 49.0
HKD1_k127_169857_4 transposase IS116 IS110 IS902 family protein K07486 - - 0.00003576 52.0
HKD1_k127_170290_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 606.0
HKD1_k127_170290_1 Domain of unknown function (DUF3382) K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 366.0
HKD1_k127_170290_2 Branched-chain amino acid transport system / permease component K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 331.0
HKD1_k127_170290_3 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002289 286.0
HKD1_k127_170290_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002001 282.0
HKD1_k127_170290_5 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.00000000000000000000134 94.0
HKD1_k127_170290_6 - - - - 0.00005627 51.0
HKD1_k127_172576_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.103e-212 681.0
HKD1_k127_172576_1 Receptor family ligand binding region K01999 - - 8.679e-210 659.0
HKD1_k127_172576_10 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 479.0
HKD1_k127_172576_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 466.0
HKD1_k127_172576_12 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 369.0
HKD1_k127_172576_13 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 390.0
HKD1_k127_172576_14 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 357.0
HKD1_k127_172576_15 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 349.0
HKD1_k127_172576_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 356.0
HKD1_k127_172576_17 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 323.0
HKD1_k127_172576_18 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000009537 231.0
HKD1_k127_172576_19 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000004629 180.0
HKD1_k127_172576_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 2.501e-202 640.0
HKD1_k127_172576_20 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000003713 157.0
HKD1_k127_172576_21 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000000000001488 160.0
HKD1_k127_172576_22 dksA traR - - - 0.0000000000000000000000419 104.0
HKD1_k127_172576_23 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000006285 93.0
HKD1_k127_172576_24 PFAM PsiF repeat protein - - - 0.0000000000000000004135 93.0
HKD1_k127_172576_25 KTSC domain - - - 0.0000000000000000006021 89.0
HKD1_k127_172576_26 Protein of unknown function (DUF3149) - - - 0.0004793 45.0
HKD1_k127_172576_27 Periplasmic Protein - GO:0003674,GO:0004857,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030234,GO:0030312,GO:0030313,GO:0031975,GO:0043086,GO:0044092,GO:0044462,GO:0044464,GO:0050790,GO:0060241,GO:0065007,GO:0065009,GO:0071944,GO:0098772 - 0.0005907 48.0
HKD1_k127_172576_28 - - - - 0.0009762 49.0
HKD1_k127_172576_3 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 600.0
HKD1_k127_172576_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 627.0
HKD1_k127_172576_5 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 551.0
HKD1_k127_172576_6 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 556.0
HKD1_k127_172576_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HKD1_k127_172576_8 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 507.0
HKD1_k127_172576_9 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 481.0
HKD1_k127_1732275_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 9.509e-245 765.0
HKD1_k127_1773759_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.624e-314 970.0
HKD1_k127_1773759_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 4.533e-234 742.0
HKD1_k127_1773759_10 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000007521 79.0
HKD1_k127_1773759_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 640.0
HKD1_k127_1773759_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 542.0
HKD1_k127_1773759_4 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 426.0
HKD1_k127_1773759_5 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 366.0
HKD1_k127_1773759_6 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
HKD1_k127_1773759_7 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000002697 169.0
HKD1_k127_1773759_8 Succinate dehydrogenase, hydrophobic K00242 - - 0.0000000000000000000000000000000008685 137.0
HKD1_k127_1773759_9 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000001557 126.0
HKD1_k127_1785734_0 AcrB/AcrD/AcrF family - - - 0.0 1300.0
HKD1_k127_1785734_1 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 2.381e-225 703.0
HKD1_k127_1785734_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 347.0
HKD1_k127_1785734_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007563 285.0
HKD1_k127_1785734_4 - K07112 - - 0.00000000000000000000000000000000000000002529 162.0
HKD1_k127_1785734_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.000000000000000000000000000000000000002981 161.0
HKD1_k127_1785734_6 Protein of unknown function (DUF2892) - - - 0.00000000000003382 85.0
HKD1_k127_1791232_0 Nucleotidyl transferase K00975 - 2.7.7.27 3.121e-212 667.0
HKD1_k127_1791232_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 606.0
HKD1_k127_1791232_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 484.0
HKD1_k127_1791232_3 Belongs to the glycosyl hydrolase 13 family K02438 - 3.2.1.196 0.0000000000000000000000001657 116.0
HKD1_k127_179671_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 424.0
HKD1_k127_179671_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0005304 54.0
HKD1_k127_1799859_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 498.0
HKD1_k127_1799859_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000002264 209.0
HKD1_k127_1799859_2 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000002371 106.0
HKD1_k127_1799859_3 epimerase K00091 - 1.1.1.219 0.0000000000000000000001291 114.0
HKD1_k127_1799859_4 Copper binding periplasmic protein CusF - - - 0.0000000000000004705 92.0
HKD1_k127_195987_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.101e-312 967.0
HKD1_k127_195987_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848,K20906 - 5.4.99.2,5.4.99.64 1.298e-290 902.0
HKD1_k127_195987_10 regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000003191 186.0
HKD1_k127_195987_11 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000003458 124.0
HKD1_k127_195987_12 PFAM RDD domain containing protein - - - 0.0000000000000000004125 94.0
HKD1_k127_195987_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.818e-251 790.0
HKD1_k127_195987_3 ArgK protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 361.0
HKD1_k127_195987_4 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 309.0
HKD1_k127_195987_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 291.0
HKD1_k127_195987_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000946 284.0
HKD1_k127_195987_7 Acetolactate synthase small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000002728 264.0
HKD1_k127_195987_8 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
HKD1_k127_195987_9 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000003717 206.0
HKD1_k127_200479_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 452.0
HKD1_k127_200479_1 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 426.0
HKD1_k127_200479_2 RmlD substrate binding domain K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 415.0
HKD1_k127_200479_3 COG1538 Outer membrane protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 362.0
HKD1_k127_200479_4 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 363.0
HKD1_k127_200479_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 283.0
HKD1_k127_200479_6 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003638 279.0
HKD1_k127_200479_7 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000001408 252.0
HKD1_k127_200479_8 Rhodanese domain protein - - - 0.000000000000000000000000000001416 134.0
HKD1_k127_2021632_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 582.0
HKD1_k127_2021632_1 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000002378 156.0
HKD1_k127_2023343_0 phenylacetic acid degradation protein paaN - - - 5.714e-262 818.0
HKD1_k127_2023343_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.146e-210 662.0
HKD1_k127_2023343_10 PaaX-like protein K02616 - - 0.0000000000000000099 85.0
HKD1_k127_2023343_2 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 590.0
HKD1_k127_2023343_3 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 544.0
HKD1_k127_2023343_4 Oxidoreductase FAD-binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 470.0
HKD1_k127_2023343_5 enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 388.0
HKD1_k127_2023343_6 phenylacetic acid K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 337.0
HKD1_k127_2023343_7 phenylacetate-CoA oxygenase, PaaJ subunit K02612 GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000004257 219.0
HKD1_k127_2023343_8 Phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000000000000000002143 198.0
HKD1_k127_2023343_9 Phenylacetic acid degradation B K02610 - - 0.00000000000000000000000000000000000000000000000000008722 186.0
HKD1_k127_2031336_0 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 499.0
HKD1_k127_2031336_1 Cytochrome bd-type quinol oxidase, subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
HKD1_k127_203283_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.173e-302 932.0
HKD1_k127_203283_1 Transposase domain (DUF772) K07487 - - 2.152e-234 733.0
HKD1_k127_203283_10 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 362.0
HKD1_k127_203283_11 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 361.0
HKD1_k127_203283_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 369.0
HKD1_k127_203283_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 310.0
HKD1_k127_203283_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 308.0
HKD1_k127_203283_15 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000131 252.0
HKD1_k127_203283_16 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
HKD1_k127_203283_17 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000004931 211.0
HKD1_k127_203283_18 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000001354 163.0
HKD1_k127_203283_19 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000134 152.0
HKD1_k127_203283_2 HELICc2 K03722 - 3.6.4.12 6.46e-234 744.0
HKD1_k127_203283_20 Protein conserved in bacteria - - - 0.000000000000000000000000001636 126.0
HKD1_k127_203283_21 GYD domain - - - 0.000000000000000000000000002139 127.0
HKD1_k127_203283_22 - - - - 0.000000000121 64.0
HKD1_k127_203283_3 Psort location Cytoplasmic, score 8.96 K07462 - - 7.344e-205 670.0
HKD1_k127_203283_4 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 589.0
HKD1_k127_203283_5 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 489.0
HKD1_k127_203283_6 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 484.0
HKD1_k127_203283_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 441.0
HKD1_k127_203283_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 368.0
HKD1_k127_203283_9 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 370.0
HKD1_k127_2034101_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 551.0
HKD1_k127_2034101_1 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 502.0
HKD1_k127_2034101_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 331.0
HKD1_k127_2034101_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007234 271.0
HKD1_k127_2034101_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000005203 208.0
HKD1_k127_2034101_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000002939 198.0
HKD1_k127_2034461_0 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 342.0
HKD1_k127_2034461_1 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 330.0
HKD1_k127_2034461_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000003829 214.0
HKD1_k127_2034461_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000001599 170.0
HKD1_k127_2035773_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1166.0
HKD1_k127_2035773_1 PFAM NapC NirT cytochrome c K02569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 293.0
HKD1_k127_2035773_2 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000003109 150.0
HKD1_k127_2045199_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 484.0
HKD1_k127_2045199_1 ATPase (AAA K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 381.0
HKD1_k127_2045199_2 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 325.0
HKD1_k127_2045199_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000003238 155.0
HKD1_k127_2045199_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000451 92.0
HKD1_k127_2054475_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.539e-280 872.0
HKD1_k127_2054475_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 7.468e-246 766.0
HKD1_k127_2054475_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 456.0
HKD1_k127_2054475_3 Catalyzes the sodium-dependent transport of glutamate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 372.0
HKD1_k127_2054475_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 362.0
HKD1_k127_2054475_5 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 324.0
HKD1_k127_2054475_6 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 302.0
HKD1_k127_2054475_7 TRAP transporter solute receptor TAXI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006085 276.0
HKD1_k127_2054475_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000002905 64.0
HKD1_k127_2070345_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 544.0
HKD1_k127_2070345_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000002276 208.0
HKD1_k127_2070345_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000001437 132.0
HKD1_k127_2070345_3 AraC-binding-like domain - - - 0.00000000001294 78.0
HKD1_k127_2081308_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1234.0
HKD1_k127_2081308_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1114.0
HKD1_k127_2081308_10 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 505.0
HKD1_k127_2081308_11 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 477.0
HKD1_k127_2081308_12 Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols K04101 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 451.0
HKD1_k127_2081308_13 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 426.0
HKD1_k127_2081308_14 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 379.0
HKD1_k127_2081308_15 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 381.0
HKD1_k127_2081308_16 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 361.0
HKD1_k127_2081308_17 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 359.0
HKD1_k127_2081308_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 344.0
HKD1_k127_2081308_19 PFAM isochorismatase hydrolase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 314.0
HKD1_k127_2081308_2 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 4.096e-227 707.0
HKD1_k127_2081308_20 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 330.0
HKD1_k127_2081308_21 Phage lysozyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 331.0
HKD1_k127_2081308_22 LysR substrate binding domain K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 297.0
HKD1_k127_2081308_23 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 316.0
HKD1_k127_2081308_24 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000008981 271.0
HKD1_k127_2081308_25 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000004198 250.0
HKD1_k127_2081308_26 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001533 232.0
HKD1_k127_2081308_27 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000003629 237.0
HKD1_k127_2081308_28 - - - - 0.00000000000000000000000000000000000000000000000000000000002774 216.0
HKD1_k127_2081308_29 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
HKD1_k127_2081308_3 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.435e-219 692.0
HKD1_k127_2081308_30 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000000000007794 180.0
HKD1_k127_2081308_31 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000002336 175.0
HKD1_k127_2081308_32 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000167 176.0
HKD1_k127_2081308_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000001398 168.0
HKD1_k127_2081308_34 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000007643 167.0
HKD1_k127_2081308_35 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000008544 167.0
HKD1_k127_2081308_36 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000103 170.0
HKD1_k127_2081308_37 FR47-like protein - - - 0.00000000000000000000000000000000000001304 157.0
HKD1_k127_2081308_38 transcriptional regulator - - - 0.0000000000000000000000000000000000002984 149.0
HKD1_k127_2081308_39 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000002765 149.0
HKD1_k127_2081308_4 Competence protein ComEC Rec2 K02238 - - 1.281e-205 668.0
HKD1_k127_2081308_40 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000001205 106.0
HKD1_k127_2081308_41 - - - - 0.000000000000000000006591 100.0
HKD1_k127_2081308_42 RecX family - - - 0.00000000000000000001137 107.0
HKD1_k127_2081308_43 - - - - 0.000000000001424 74.0
HKD1_k127_2081308_44 Glutathione S-transferase, N-terminal domain K01801 - 5.2.1.4 0.0001242 44.0
HKD1_k127_2081308_5 ABC transporter substrate-binding protein K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 594.0
HKD1_k127_2081308_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 568.0
HKD1_k127_2081308_7 PrpF protein K16514 - 5.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 524.0
HKD1_k127_2081308_8 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 512.0
HKD1_k127_2081308_9 oxidoreductase K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 499.0
HKD1_k127_2105671_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 352.0
HKD1_k127_2105671_1 CHASE3 domain K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000002688 262.0
HKD1_k127_2105671_2 response regulator - - - 0.000000000000000000000000000000000000000002422 161.0
HKD1_k127_2110175_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 342.0
HKD1_k127_2110175_1 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004218 262.0
HKD1_k127_2110175_2 Regulatory protein, FmdB family - - - 0.00000000000000000000000000003538 120.0
HKD1_k127_2120443_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 464.0
HKD1_k127_2120443_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 296.0
HKD1_k127_2120443_2 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000000000000000006025 225.0
HKD1_k127_2123653_0 Asparagine synthase K01953 - 6.3.5.4 3.059e-317 985.0
HKD1_k127_2123653_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 424.0
HKD1_k127_2123653_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 361.0
HKD1_k127_2124948_0 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 552.0
HKD1_k127_2124948_1 abc transporter K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 487.0
HKD1_k127_2124948_2 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 412.0
HKD1_k127_2124948_3 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001325 269.0
HKD1_k127_2125870_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 300.0
HKD1_k127_2125870_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000001208 129.0
HKD1_k127_2132923_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.175e-311 979.0
HKD1_k127_2132923_1 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 492.0
HKD1_k127_2132923_10 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000001392 204.0
HKD1_k127_2132923_11 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000001255 131.0
HKD1_k127_2132923_2 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 407.0
HKD1_k127_2132923_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 414.0
HKD1_k127_2132923_4 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 365.0
HKD1_k127_2132923_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 358.0
HKD1_k127_2132923_6 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003549 258.0
HKD1_k127_2132923_7 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000217 239.0
HKD1_k127_2132923_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000001034 250.0
HKD1_k127_2132923_9 plastoquinol--plastocyanin reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003453 236.0
HKD1_k127_2172632_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 573.0
HKD1_k127_2172632_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 577.0
HKD1_k127_2172632_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000005013 271.0
HKD1_k127_2172632_11 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000001098 198.0
HKD1_k127_2172632_12 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000003162 175.0
HKD1_k127_2172632_13 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000001093 135.0
HKD1_k127_2172632_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000001527 117.0
HKD1_k127_2172632_15 Belongs to the BolA IbaG family - - - 0.000000000000000000000000346 121.0
HKD1_k127_2172632_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000006944 106.0
HKD1_k127_2172632_17 - - - - 0.000000000000002134 87.0
HKD1_k127_2172632_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 416.0
HKD1_k127_2172632_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 404.0
HKD1_k127_2172632_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 369.0
HKD1_k127_2172632_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 351.0
HKD1_k127_2172632_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 319.0
HKD1_k127_2172632_7 Sec-independent protein translocase protein (TatC) K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 318.0
HKD1_k127_2172632_8 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 321.0
HKD1_k127_2172632_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 289.0
HKD1_k127_2175505_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 1.326e-283 881.0
HKD1_k127_2175505_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.689e-258 828.0
HKD1_k127_2175505_10 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 610.0
HKD1_k127_2175505_11 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 555.0
HKD1_k127_2175505_12 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 526.0
HKD1_k127_2175505_13 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 510.0
HKD1_k127_2175505_14 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 522.0
HKD1_k127_2175505_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 475.0
HKD1_k127_2175505_16 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 485.0
HKD1_k127_2175505_17 C4-dicarboxylate ABC transporter K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 486.0
HKD1_k127_2175505_18 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 480.0
HKD1_k127_2175505_19 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 423.0
HKD1_k127_2175505_2 cellulose binding - - - 1.537e-251 820.0
HKD1_k127_2175505_20 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 399.0
HKD1_k127_2175505_21 Male sterility protein K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 393.0
HKD1_k127_2175505_22 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 394.0
HKD1_k127_2175505_23 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 387.0
HKD1_k127_2175505_24 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 384.0
HKD1_k127_2175505_25 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 381.0
HKD1_k127_2175505_26 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 380.0
HKD1_k127_2175505_27 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 369.0
HKD1_k127_2175505_28 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 342.0
HKD1_k127_2175505_29 Protein of unknown function (DUF3182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 339.0
HKD1_k127_2175505_3 PFAM Amylo-alpha-16-glucosidase - - - 2.186e-247 787.0
HKD1_k127_2175505_30 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 327.0
HKD1_k127_2175505_31 Uncharacterised protein family (UPF0227) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 327.0
HKD1_k127_2175505_32 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 328.0
HKD1_k127_2175505_33 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 317.0
HKD1_k127_2175505_34 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 307.0
HKD1_k127_2175505_35 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002202 310.0
HKD1_k127_2175505_36 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
HKD1_k127_2175505_37 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000003108 276.0
HKD1_k127_2175505_38 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000001096 271.0
HKD1_k127_2175505_39 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003074 261.0
HKD1_k127_2175505_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.682e-246 782.0
HKD1_k127_2175505_40 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002828 261.0
HKD1_k127_2175505_41 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000002179 247.0
HKD1_k127_2175505_42 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001333 246.0
HKD1_k127_2175505_43 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000004014 234.0
HKD1_k127_2175505_44 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008512 237.0
HKD1_k127_2175505_45 glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000002461 234.0
HKD1_k127_2175505_46 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000003041 237.0
HKD1_k127_2175505_47 HemY domain protein K02498 - - 0.000000000000000000000000000000000000000000000000000000000000002669 232.0
HKD1_k127_2175505_48 Gaf domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001067 227.0
HKD1_k127_2175505_49 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000001121 225.0
HKD1_k127_2175505_5 Rieske-like [2Fe-2S] domain - - - 1.509e-239 754.0
HKD1_k127_2175505_50 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000003865 216.0
HKD1_k127_2175505_51 Lactoylglutathione lyase - - - 0.00000000000000000000000000000000000000000000000000000006239 197.0
HKD1_k127_2175505_52 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000004252 196.0
HKD1_k127_2175505_53 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000002061 193.0
HKD1_k127_2175505_54 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000007693 185.0
HKD1_k127_2175505_55 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000001193 180.0
HKD1_k127_2175505_56 Restriction endonuclease - - - 0.00000000000000000000000000000000000000000000007438 172.0
HKD1_k127_2175505_57 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000001904 184.0
HKD1_k127_2175505_58 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000002094 169.0
HKD1_k127_2175505_59 - - - - 0.000000000000000000000000000000000000000000004816 169.0
HKD1_k127_2175505_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.283e-226 708.0
HKD1_k127_2175505_60 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000001102 171.0
HKD1_k127_2175505_61 2OG-Fe(II) oxygenase superfamily K07394 - - 0.0000000000000000000000000000000000000000003484 166.0
HKD1_k127_2175505_62 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000001733 143.0
HKD1_k127_2175505_63 Cytochrome c - - - 0.00000000000000000000000000000000002347 147.0
HKD1_k127_2175505_64 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000008819 133.0
HKD1_k127_2175505_66 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000000000000002472 113.0
HKD1_k127_2175505_67 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000004137 109.0
HKD1_k127_2175505_68 Thioredoxin-like - - - 0.000000000000000000000006873 115.0
HKD1_k127_2175505_69 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000385 102.0
HKD1_k127_2175505_7 protein involved in propionate catabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 629.0
HKD1_k127_2175505_70 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000007622 109.0
HKD1_k127_2175505_71 membrane - - - 0.0000000000000000000008324 100.0
HKD1_k127_2175505_72 response regulator - - - 0.000000000000000000002365 106.0
HKD1_k127_2175505_73 membrane - - - 0.0000000000000000001776 91.0
HKD1_k127_2175505_74 membrane - - - 0.000000000000000005374 89.0
HKD1_k127_2175505_75 Protein of unknown function (DUF3309) - - - 0.00000000000000008689 80.0
HKD1_k127_2175505_76 - - - - 0.0000000000000005129 80.0
HKD1_k127_2175505_77 Histidine kinase - - - 0.00000000000000112 85.0
HKD1_k127_2175505_78 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000002185 86.0
HKD1_k127_2175505_79 UPF0391 membrane protein - - - 0.00000000000004205 77.0
HKD1_k127_2175505_8 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 618.0
HKD1_k127_2175505_80 PRC-barrel domain - - - 0.00000000000004946 73.0
HKD1_k127_2175505_81 Transcriptional regulator - - - 0.0000000000001615 77.0
HKD1_k127_2175505_83 PGAP1-like protein - - - 0.00000000005635 65.0
HKD1_k127_2175505_85 - - - - 0.0000000003111 71.0
HKD1_k127_2175505_86 Membrane transport protein K07088 - - 0.000000001809 63.0
HKD1_k127_2175505_87 Glycine zipper 2TM domain K04062 - - 0.000000002333 64.0
HKD1_k127_2175505_88 Bacterial regulatory proteins, tetR family - - - 0.000000008957 65.0
HKD1_k127_2175505_89 SMART Transport-associated and nodulation - - - 0.000000108 62.0
HKD1_k127_2175505_9 L-carnitine dehydratase bile acid-inducible protein F K18289 - 2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 602.0
HKD1_k127_2175505_90 Protein of unknown function (DUF1328) - - - 0.0000005681 59.0
HKD1_k127_2175505_91 ribosome binding - - - 0.000001165 58.0
HKD1_k127_2175505_92 Histidine kinase - - - 0.00001442 55.0
HKD1_k127_2175505_93 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00004342 49.0
HKD1_k127_2188186_0 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 6.559e-208 684.0
HKD1_k127_2188186_1 ERAP1-like C-terminal domain K01263 - 3.4.11.14 1.359e-196 654.0
HKD1_k127_2188186_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 324.0
HKD1_k127_2188186_11 PFAM Spermine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
HKD1_k127_2188186_12 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000007412 238.0
HKD1_k127_2188186_13 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002131 248.0
HKD1_k127_2188186_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000001458 183.0
HKD1_k127_2188186_15 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000003373 175.0
HKD1_k127_2188186_16 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000006355 164.0
HKD1_k127_2188186_17 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000215 143.0
HKD1_k127_2188186_18 isochorismatase - - - 0.00000000000000000000000000000000003882 148.0
HKD1_k127_2188186_19 - - - - 0.0000000000000000000000000000001964 133.0
HKD1_k127_2188186_2 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 610.0
HKD1_k127_2188186_20 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.0000000000000000000000000000009457 127.0
HKD1_k127_2188186_21 Dodecin K09165 - - 0.0000000000000000000000005203 121.0
HKD1_k127_2188186_22 - - - - 0.00000000000000000000006616 112.0
HKD1_k127_2188186_23 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000183 97.0
HKD1_k127_2188186_24 MerR HTH family regulatory protein K18997 - - 0.0000006502 61.0
HKD1_k127_2188186_25 LTXXQ motif family protein - - - 0.000006619 55.0
HKD1_k127_2188186_3 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 571.0
HKD1_k127_2188186_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 563.0
HKD1_k127_2188186_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 518.0
HKD1_k127_2188186_6 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 495.0
HKD1_k127_2188186_7 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 437.0
HKD1_k127_2188186_8 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 332.0
HKD1_k127_2188186_9 PFAM heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 346.0
HKD1_k127_2194167_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.586e-217 677.0
HKD1_k127_2194167_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 456.0
HKD1_k127_2194167_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 453.0
HKD1_k127_2194167_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 344.0
HKD1_k127_2194167_4 Sporulation related domain K03749 - - 0.00000000000003784 83.0
HKD1_k127_224363_0 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 318.0
HKD1_k127_224363_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001062 254.0
HKD1_k127_224363_2 - - - - 0.000000000000000000000000000000000000000000000000001014 202.0
HKD1_k127_224363_3 - - - - 0.00000000000000000000000000000002622 142.0
HKD1_k127_224363_4 Tetratricopeptide repeat - - - 0.00000000000000000000002301 115.0
HKD1_k127_224363_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000002265 60.0
HKD1_k127_2282198_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 3.449e-294 929.0
HKD1_k127_2282198_1 transport system, fused permease components - - - 2.778e-283 894.0
HKD1_k127_2282198_10 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 443.0
HKD1_k127_2282198_11 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 417.0
HKD1_k127_2282198_12 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 404.0
HKD1_k127_2282198_13 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
HKD1_k127_2282198_14 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 336.0
HKD1_k127_2282198_15 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009962 282.0
HKD1_k127_2282198_16 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003297 231.0
HKD1_k127_2282198_17 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000001478 224.0
HKD1_k127_2282198_18 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000003397 196.0
HKD1_k127_2282198_19 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000006299 197.0
HKD1_k127_2282198_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 572.0
HKD1_k127_2282198_20 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000006272 183.0
HKD1_k127_2282198_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000001506 184.0
HKD1_k127_2282198_22 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000005587 190.0
HKD1_k127_2282198_23 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000915 182.0
HKD1_k127_2282198_24 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000001357 168.0
HKD1_k127_2282198_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000371 144.0
HKD1_k127_2282198_26 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.000000000000000000000000000000008912 135.0
HKD1_k127_2282198_27 - - - - 0.00000000000000000000000003525 120.0
HKD1_k127_2282198_28 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000008955 111.0
HKD1_k127_2282198_29 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000002248 94.0
HKD1_k127_2282198_3 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 557.0
HKD1_k127_2282198_30 - - - - 0.00000000000000000001446 104.0
HKD1_k127_2282198_31 - - - - 0.00000000000000000004529 102.0
HKD1_k127_2282198_32 - - - - 0.0000000000000000001413 95.0
HKD1_k127_2282198_33 Domain of unknown function (DUF1850) - - - 0.00000000000006496 79.0
HKD1_k127_2282198_4 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 524.0
HKD1_k127_2282198_5 Belongs to the aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 503.0
HKD1_k127_2282198_6 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 501.0
HKD1_k127_2282198_7 fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 469.0
HKD1_k127_2282198_8 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 454.0
HKD1_k127_2282198_9 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 452.0
HKD1_k127_2296442_0 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 455.0
HKD1_k127_2296442_1 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000371 265.0
HKD1_k127_2347145_0 Arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 511.0
HKD1_k127_2347145_1 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 312.0
HKD1_k127_2347145_2 Patatin-like phospholipase K07001 - - 0.00000002829 63.0
HKD1_k127_2364618_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 422.0
HKD1_k127_2364618_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000001312 104.0
HKD1_k127_2364618_2 Protein of unknown function (DUF721) - - - 0.00002294 51.0
HKD1_k127_2364618_3 - - - - 0.00004456 48.0
HKD1_k127_2374630_0 NnrS protein K07234 - - 4.295e-197 621.0
HKD1_k127_2374630_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 417.0
HKD1_k127_2374630_2 ferredoxin--nadp reductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005074 263.0
HKD1_k127_2374630_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000001364 194.0
HKD1_k127_2374630_4 Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity K13771 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000005524 186.0
HKD1_k127_2374630_5 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000003626 76.0
HKD1_k127_2379508_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 1.124e-231 723.0
HKD1_k127_2379508_1 Extracellular solute-binding protein, family 3 K16254 - - 0.00000000000002675 81.0
HKD1_k127_2407936_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.958e-212 678.0
HKD1_k127_2452987_0 Acts as a magnesium transporter K06213 - - 4.56e-199 631.0
HKD1_k127_2452987_1 RNB K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 589.0
HKD1_k127_2452987_10 - - - - 0.000000000000000000000000006233 117.0
HKD1_k127_2452987_2 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 537.0
HKD1_k127_2452987_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 488.0
HKD1_k127_2452987_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 317.0
HKD1_k127_2452987_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 304.0
HKD1_k127_2452987_6 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001926 287.0
HKD1_k127_2452987_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000000000000000105 216.0
HKD1_k127_2452987_8 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000002266 197.0
HKD1_k127_2452987_9 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000001005 151.0
HKD1_k127_2553281_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.866e-316 975.0
HKD1_k127_2613663_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.625e-211 668.0
HKD1_k127_2613663_1 twitching motility protein K02670 - - 3.083e-201 634.0
HKD1_k127_2613663_10 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 376.0
HKD1_k127_2613663_11 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 330.0
HKD1_k127_2613663_12 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 349.0
HKD1_k127_2613663_13 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 314.0
HKD1_k127_2613663_14 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 314.0
HKD1_k127_2613663_15 KR domain K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 305.0
HKD1_k127_2613663_16 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001633 272.0
HKD1_k127_2613663_17 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000003219 246.0
HKD1_k127_2613663_18 Serine aminopeptidase, S33 K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000004265 231.0
HKD1_k127_2613663_19 lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000504 242.0
HKD1_k127_2613663_2 twitching motility protein K02669 - - 6.854e-196 613.0
HKD1_k127_2613663_20 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000001402 209.0
HKD1_k127_2613663_21 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000001062 224.0
HKD1_k127_2613663_22 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000001066 199.0
HKD1_k127_2613663_23 import inner membrane translocase subunit Tim44 - - - 0.000000000000000000000000000000000000000000000003883 196.0
HKD1_k127_2613663_24 Ferredoxin - - - 0.0000000000000000000000000000000000000000005575 161.0
HKD1_k127_2613663_25 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000006755 170.0
HKD1_k127_2613663_26 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000004636 149.0
HKD1_k127_2613663_27 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.0000000000000000000000000000000000004231 148.0
HKD1_k127_2613663_28 VanZ like family - - - 0.00000000000000000000000000000000001441 149.0
HKD1_k127_2613663_29 FabA-like domain - - - 0.0000000000000000000003416 106.0
HKD1_k127_2613663_3 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 534.0
HKD1_k127_2613663_30 Phospholipid methyltransferase - - - 0.0000000000004071 83.0
HKD1_k127_2613663_31 SCP-2 sterol transfer family K03690 - - 0.000000000004935 76.0
HKD1_k127_2613663_33 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0003006 54.0
HKD1_k127_2613663_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 524.0
HKD1_k127_2613663_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 455.0
HKD1_k127_2613663_6 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 437.0
HKD1_k127_2613663_7 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 432.0
HKD1_k127_2613663_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 426.0
HKD1_k127_2613663_9 THUMP K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 409.0
HKD1_k127_262192_0 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 596.0
HKD1_k127_262192_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 298.0
HKD1_k127_262192_2 LssY C-terminus - - - 0.00000000000000000000000000000000000000001723 174.0
HKD1_k127_262192_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000003311 95.0
HKD1_k127_2641082_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.967e-229 715.0
HKD1_k127_2641082_1 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002011 289.0
HKD1_k127_2674799_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.822e-234 732.0
HKD1_k127_2674799_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 424.0
HKD1_k127_2674799_2 Domain of unknown function (DUF4124) - - - 0.00000000217 65.0
HKD1_k127_2695669_0 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0 1487.0
HKD1_k127_2695669_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1234.0
HKD1_k127_2695669_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 354.0
HKD1_k127_2695669_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 345.0
HKD1_k127_2695669_12 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 377.0
HKD1_k127_2695669_13 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 292.0
HKD1_k127_2695669_14 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002552 278.0
HKD1_k127_2695669_15 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 269.0
HKD1_k127_2695669_16 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000268 253.0
HKD1_k127_2695669_17 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 256.0
HKD1_k127_2695669_18 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002276 241.0
HKD1_k127_2695669_19 SmpB protein K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
HKD1_k127_2695669_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1013.0
HKD1_k127_2695669_20 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000008909 226.0
HKD1_k127_2695669_21 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000002075 221.0
HKD1_k127_2695669_22 Type II secretion system protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000001203 211.0
HKD1_k127_2695669_23 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000006168 195.0
HKD1_k127_2695669_24 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000001471 178.0
HKD1_k127_2695669_25 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000001494 175.0
HKD1_k127_2695669_26 PFAM Type IV pilus assembly PilZ K02676 - - 0.0000000000000000000000000000000000000000002858 161.0
HKD1_k127_2695669_27 Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000001484 154.0
HKD1_k127_2695669_28 bacterial (prokaryotic) histone like domain - - - 0.000000000000000000000000000000001093 137.0
HKD1_k127_2695669_29 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000000000001416 106.0
HKD1_k127_2695669_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.304e-292 911.0
HKD1_k127_2695669_30 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000003365 102.0
HKD1_k127_2695669_31 - - - - 0.0000000000002522 73.0
HKD1_k127_2695669_32 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000003694 73.0
HKD1_k127_2695669_33 general secretion pathway protein K02456,K02457,K02458,K02650 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000003393 61.0
HKD1_k127_2695669_34 General secretion pathway K02461 - - 0.000005293 59.0
HKD1_k127_2695669_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.966e-219 685.0
HKD1_k127_2695669_5 AMP-binding enzyme C-terminal domain K00666 - - 1.511e-216 690.0
HKD1_k127_2695669_6 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 498.0
HKD1_k127_2695669_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 462.0
HKD1_k127_2695669_8 Alkaline and neutral invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 439.0
HKD1_k127_2695669_9 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 360.0
HKD1_k127_2760950_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1022.0
HKD1_k127_2760950_1 Protein of unknown function, DUF255 - - - 2.292e-237 753.0
HKD1_k127_2760950_10 Protein of unknown function (DUF2917) - - - 0.00003591 56.0
HKD1_k127_2760950_2 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 507.0
HKD1_k127_2760950_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 431.0
HKD1_k127_2760950_4 Transcriptional regulatory protein, C terminal K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 298.0
HKD1_k127_2760950_5 - - - - 0.000000000000000000000000000000000000000000000000000000001445 224.0
HKD1_k127_2760950_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000001626 185.0
HKD1_k127_2760950_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000003397 130.0
HKD1_k127_2760950_8 Cytochrome c K08738 - - 0.000000000000000000000000002846 117.0
HKD1_k127_2760950_9 PFAM MAPEG family - - - 0.00000105 51.0
HKD1_k127_2795320_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 8.606e-309 963.0
HKD1_k127_2795320_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 496.0
HKD1_k127_2795320_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 329.0
HKD1_k127_2795320_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002455 275.0
HKD1_k127_2795320_4 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000006628 205.0
HKD1_k127_2795320_5 Small MutS-related domain - - - 0.0000000000000000000000000000000000000000009744 166.0
HKD1_k127_2795320_6 AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000006982 155.0
HKD1_k127_2907359_0 PFAM Type II secretion system protein E K02454 - - 1.554e-213 677.0
HKD1_k127_2907359_1 Aminotransferase K01845 - 5.4.3.8 1.057e-194 616.0
HKD1_k127_2907359_10 oxidase assembly K02258 - - 0.0000000000000000000000000000000000000000000004518 169.0
HKD1_k127_2907359_11 TIGRFAM general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000006324 162.0
HKD1_k127_2907359_12 signal sequence binding - - - 0.000000000000000000000000000000001314 142.0
HKD1_k127_2907359_13 General secretion pathway protein H K02457 - - 0.0000000000000000000000000003416 126.0
HKD1_k127_2907359_14 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000001915 115.0
HKD1_k127_2907359_15 Protein of unknown function (DUF2909) - - - 0.00000000000003027 75.0
HKD1_k127_2907359_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 414.0
HKD1_k127_2907359_3 Type II secretion system K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 404.0
HKD1_k127_2907359_4 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 397.0
HKD1_k127_2907359_5 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 398.0
HKD1_k127_2907359_6 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002486 263.0
HKD1_k127_2907359_7 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000005776 206.0
HKD1_k127_2907359_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000431 190.0
HKD1_k127_2907359_9 SURF1 family - - - 0.00000000000000000000000000000000000000000000005005 182.0
HKD1_k127_3017348_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 2.091e-304 946.0
HKD1_k127_3017348_1 glycosyl transferase family 2 K20444 - - 4.203e-275 913.0
HKD1_k127_3017348_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000001114 235.0
HKD1_k127_3017348_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000008439 220.0
HKD1_k127_3017348_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000001108 209.0
HKD1_k127_3017348_13 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000003374 187.0
HKD1_k127_3017348_14 CBS domain - - - 0.000000000000000000003545 99.0
HKD1_k127_3017348_15 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000001225 87.0
HKD1_k127_3017348_16 Putative zinc-finger - - - 0.0000004241 55.0
HKD1_k127_3017348_2 ABC-type sugar transport system periplasmic component K02027,K05813 - - 2.847e-216 675.0
HKD1_k127_3017348_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 577.0
HKD1_k127_3017348_4 Binding-protein-dependent transport system inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 449.0
HKD1_k127_3017348_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 409.0
HKD1_k127_3017348_6 ABC-type sugar transport system, permease component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 419.0
HKD1_k127_3017348_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 317.0
HKD1_k127_3017348_8 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 285.0
HKD1_k127_3017348_9 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000768 273.0
HKD1_k127_3040365_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.304e-280 871.0
HKD1_k127_3040365_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 559.0
HKD1_k127_3040365_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 380.0
HKD1_k127_3040365_3 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
HKD1_k127_3040365_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000000000000003801 175.0
HKD1_k127_3040365_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000009791 151.0
HKD1_k127_3040365_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000003009 147.0
HKD1_k127_3040365_7 ThiS family K03636 - - 0.0000000000000008517 81.0
HKD1_k127_3040365_8 ATP synthase I chain K02116 - - 0.00000000000133 73.0
HKD1_k127_3040365_9 Belongs to the ParB family K03497 - - 0.0000009881 50.0
HKD1_k127_3045927_0 Orn/Lys/Arg decarboxylase, N-terminal domain - - - 0.0 1362.0
HKD1_k127_3045927_1 Belongs to the TPP enzyme family K03852 - 2.3.3.15 1.872e-276 861.0
HKD1_k127_3045927_10 taurine ABC transporter, periplasmic binding protein K15551 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 413.0
HKD1_k127_3045927_11 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 385.0
HKD1_k127_3045927_12 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 372.0
HKD1_k127_3045927_13 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 361.0
HKD1_k127_3045927_14 )-tartrate dehydratase K03780 GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 306.0
HKD1_k127_3045927_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000004377 217.0
HKD1_k127_3045927_16 Endoribonuclease L-PSP K09021 - - 0.000000000000000000000000000000000001089 161.0
HKD1_k127_3045927_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000002937 141.0
HKD1_k127_3045927_18 succinate dehydrogenase K00247 - - 0.000000000000000000000000000006389 128.0
HKD1_k127_3045927_19 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.000000000000000000000001163 116.0
HKD1_k127_3045927_2 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 6.869e-261 811.0
HKD1_k127_3045927_3 GMC oxidoreductase K00108 - 1.1.99.1 1.89e-246 770.0
HKD1_k127_3045927_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 601.0
HKD1_k127_3045927_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 579.0
HKD1_k127_3045927_6 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 537.0
HKD1_k127_3045927_7 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 555.0
HKD1_k127_3045927_8 Tartrate K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 450.0
HKD1_k127_3045927_9 binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 439.0
HKD1_k127_3069758_0 Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway K18456 - 3.5.4.32 3.482e-218 684.0
HKD1_k127_3069758_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 591.0
HKD1_k127_3069758_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000001936 174.0
HKD1_k127_3069758_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000001251 157.0
HKD1_k127_3069758_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000001115 62.0
HKD1_k127_3069758_5 Helix-turn-helix domain - - - 0.000003978 51.0
HKD1_k127_3095005_0 Pfam Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 468.0
HKD1_k127_3095005_1 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 310.0
HKD1_k127_3095005_2 Hydrolase, alpha beta domain protein K01066 - - 0.00000000000000000000000000000000000000000000000000000000000004679 226.0
HKD1_k127_3095005_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000008121 207.0
HKD1_k127_3095005_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000000000000000003514 191.0
HKD1_k127_3095005_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001099 154.0
HKD1_k127_3095005_6 cytidine deaminase activity K01489 - 3.5.4.5 0.00000000000000000000000000000000001096 141.0
HKD1_k127_3095005_7 TPM domain - - - 0.0000000000000000000000000000000001161 141.0
HKD1_k127_3095005_8 Methionine synthase K00548 - 2.1.1.13 0.00000000000000008499 87.0
HKD1_k127_3095005_9 PFAM Sporulation domain protein - - - 0.000000000000002513 84.0
HKD1_k127_3102602_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 307.0
HKD1_k127_3102602_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000331 167.0
HKD1_k127_3104966_0 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 7.667e-196 621.0
HKD1_k127_3104966_1 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 507.0
HKD1_k127_3104966_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 495.0
HKD1_k127_3104966_3 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000000000000000000000000000001439 203.0
HKD1_k127_3115014_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1304.0
HKD1_k127_3115014_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.592e-205 660.0
HKD1_k127_3115014_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 400.0
HKD1_k127_3115014_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 404.0
HKD1_k127_3115014_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 391.0
HKD1_k127_3115014_13 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 352.0
HKD1_k127_3115014_14 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 334.0
HKD1_k127_3115014_15 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 302.0
HKD1_k127_3115014_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000001029 230.0
HKD1_k127_3115014_17 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000001946 192.0
HKD1_k127_3115014_18 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000001614 165.0
HKD1_k127_3115014_19 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000007952 100.0
HKD1_k127_3115014_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.128e-205 663.0
HKD1_k127_3115014_20 Outer membrane protein, OMP85 family K07278 - - 0.00000000000000006885 91.0
HKD1_k127_3115014_21 Protein of unknown function (DUF721) - - - 0.0000005342 57.0
HKD1_k127_3115014_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 616.0
HKD1_k127_3115014_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 594.0
HKD1_k127_3115014_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 527.0
HKD1_k127_3115014_6 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 464.0
HKD1_k127_3115014_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 466.0
HKD1_k127_3115014_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 424.0
HKD1_k127_3115014_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 422.0
HKD1_k127_3116788_0 Protein of unknown function (DUF3141) - - - 0.0 1049.0
HKD1_k127_3116788_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 1.399e-230 733.0
HKD1_k127_3116788_10 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 400.0
HKD1_k127_3116788_11 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 313.0
HKD1_k127_3116788_12 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004477 263.0
HKD1_k127_3116788_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000002482 231.0
HKD1_k127_3116788_14 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000449 200.0
HKD1_k127_3116788_15 membrane - - - 0.0000000000000000000000000000000000000000000000372 194.0
HKD1_k127_3116788_16 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000000000000003939 173.0
HKD1_k127_3116788_17 Protein of unknown function (DUF3302) - - - 0.00000000000000000000000000000000000000001267 162.0
HKD1_k127_3116788_18 - - - - 0.0000000000000000000000000000000000000003074 166.0
HKD1_k127_3116788_19 - - - - 0.00000000000000000000000000000000000383 144.0
HKD1_k127_3116788_2 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 505.0
HKD1_k127_3116788_20 Family of unknown function (DUF5329) - - - 0.00000000000000000000000000000000001573 138.0
HKD1_k127_3116788_21 Na( )-dependent transporter - - - 0.000000000000000000000004375 112.0
HKD1_k127_3116788_22 - - - - 0.00000000000000000000003446 104.0
HKD1_k127_3116788_23 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.0000001441 60.0
HKD1_k127_3116788_24 general secretion pathway protein - - - 0.000007611 51.0
HKD1_k127_3116788_25 - - - - 0.0002511 49.0
HKD1_k127_3116788_3 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 518.0
HKD1_k127_3116788_4 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 431.0
HKD1_k127_3116788_5 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 448.0
HKD1_k127_3116788_6 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 426.0
HKD1_k127_3116788_7 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 421.0
HKD1_k127_3116788_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 439.0
HKD1_k127_3116788_9 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 435.0
HKD1_k127_3118108_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.951e-305 945.0
HKD1_k127_3118108_1 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000004158 143.0
HKD1_k127_3118108_2 Succinate dehydrogenase, hydrophobic K00242 - - 0.00000000000001659 74.0
HKD1_k127_3121648_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1695.0
HKD1_k127_3121648_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.128e-217 681.0
HKD1_k127_3121648_10 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K00567 - 2.1.1.63 0.000000000000000000000000000000000000001773 167.0
HKD1_k127_3121648_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 545.0
HKD1_k127_3121648_3 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 441.0
HKD1_k127_3121648_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 369.0
HKD1_k127_3121648_5 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 359.0
HKD1_k127_3121648_6 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 333.0
HKD1_k127_3121648_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002049 267.0
HKD1_k127_3121648_8 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
HKD1_k127_3121648_9 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000000000000000000000000000000000000000000000000000000003492 204.0
HKD1_k127_3125208_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 8.105e-226 706.0
HKD1_k127_3125208_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 615.0
HKD1_k127_3125208_10 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 505.0
HKD1_k127_3125208_11 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 484.0
HKD1_k127_3125208_12 e3 binding domain K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 484.0
HKD1_k127_3125208_13 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 463.0
HKD1_k127_3125208_14 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 420.0
HKD1_k127_3125208_15 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 422.0
HKD1_k127_3125208_16 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 411.0
HKD1_k127_3125208_17 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 426.0
HKD1_k127_3125208_18 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 415.0
HKD1_k127_3125208_19 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K08318 - 1.1.1.373,1.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 398.0
HKD1_k127_3125208_2 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 612.0
HKD1_k127_3125208_20 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 386.0
HKD1_k127_3125208_21 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 368.0
HKD1_k127_3125208_22 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 362.0
HKD1_k127_3125208_23 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 364.0
HKD1_k127_3125208_24 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 360.0
HKD1_k127_3125208_25 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
HKD1_k127_3125208_26 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 330.0
HKD1_k127_3125208_27 ABC transporter permease K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 313.0
HKD1_k127_3125208_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 317.0
HKD1_k127_3125208_29 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 315.0
HKD1_k127_3125208_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 591.0
HKD1_k127_3125208_30 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 284.0
HKD1_k127_3125208_31 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
HKD1_k127_3125208_32 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002818 277.0
HKD1_k127_3125208_33 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000001321 258.0
HKD1_k127_3125208_34 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000000000000001587 204.0
HKD1_k127_3125208_35 Protein of unknown function DUF126 K09128 - - 0.00000000000000000000000000000000000000000000000000191 201.0
HKD1_k127_3125208_36 - - - - 0.0000000000000000000000000000000000000000000000003665 184.0
HKD1_k127_3125208_37 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000001769 172.0
HKD1_k127_3125208_38 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000006639 161.0
HKD1_k127_3125208_39 GntR family transcriptional regulator K03486,K03710 - - 0.0000000000000000000000000000000000000000114 168.0
HKD1_k127_3125208_4 Conserved carboxylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 579.0
HKD1_k127_3125208_40 Cas6 Crispr - - - 0.0000000000000000000000000000000002558 145.0
HKD1_k127_3125208_41 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000332 147.0
HKD1_k127_3125208_42 Peptidase S24-like - - - 0.0000000000000000000000000008827 126.0
HKD1_k127_3125208_43 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000001078 116.0
HKD1_k127_3125208_44 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000007076 113.0
HKD1_k127_3125208_45 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.0000000000000000000005527 105.0
HKD1_k127_3125208_46 - - - - 0.0000000000000000001274 95.0
HKD1_k127_3125208_47 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000003958 96.0
HKD1_k127_3125208_48 Spore Coat Protein U domain - - - 0.0000000000002092 78.0
HKD1_k127_3125208_49 - - - - 0.000000000001459 74.0
HKD1_k127_3125208_5 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 563.0
HKD1_k127_3125208_50 - - - - 0.000000000001713 70.0
HKD1_k127_3125208_51 Spore Coat Protein U domain - - - 0.000351 51.0
HKD1_k127_3125208_6 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 553.0
HKD1_k127_3125208_7 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 529.0
HKD1_k127_3125208_8 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 506.0
HKD1_k127_3125208_9 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 497.0
HKD1_k127_3146258_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 583.0
HKD1_k127_3146258_1 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 504.0
HKD1_k127_3146258_2 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000002275 156.0
HKD1_k127_3147082_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 1.434e-285 885.0
HKD1_k127_3147082_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 483.0
HKD1_k127_3147082_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 340.0
HKD1_k127_3147082_3 Tripartite ATP-independent periplasmic transporters, DctQ component K11689,K21394 - - 0.0000000000000000000000000000000000000000000000000000000000001153 220.0
HKD1_k127_3147082_4 Malonate decarboxylase K13932 - 4.1.1.87 0.0000000000000000000000009914 119.0
HKD1_k127_3151876_0 glucuronate isomerase K01812 - 5.3.1.12 3.707e-230 726.0
HKD1_k127_3151876_1 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 612.0
HKD1_k127_3151876_10 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 322.0
HKD1_k127_3151876_11 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 320.0
HKD1_k127_3151876_12 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 291.0
HKD1_k127_3151876_13 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 258.0
HKD1_k127_3151876_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005756 254.0
HKD1_k127_3151876_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000002565 228.0
HKD1_k127_3151876_16 FCD - - - 0.00000000000000000000000000000000000000000000000000001018 199.0
HKD1_k127_3151876_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000001389 201.0
HKD1_k127_3151876_18 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000006413 158.0
HKD1_k127_3151876_19 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000003904 123.0
HKD1_k127_3151876_2 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 518.0
HKD1_k127_3151876_20 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000007404 106.0
HKD1_k127_3151876_21 PFAM Cupin 2, conserved barrel domain protein - - - 0.00004089 51.0
HKD1_k127_3151876_3 PFAM aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 481.0
HKD1_k127_3151876_4 abc transporter K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 451.0
HKD1_k127_3151876_5 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 422.0
HKD1_k127_3151876_6 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 421.0
HKD1_k127_3151876_7 peptidase m48, ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 432.0
HKD1_k127_3151876_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 401.0
HKD1_k127_3151876_9 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 329.0
HKD1_k127_3154655_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 4.689e-266 837.0
HKD1_k127_3154655_1 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.062e-263 819.0
HKD1_k127_3154655_10 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.0000000000000000000000000000000000000000003077 173.0
HKD1_k127_3154655_11 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000001647 134.0
HKD1_k127_3154655_12 Domain of unknown function (DUF4124) - - - 0.000000000001648 76.0
HKD1_k127_3154655_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 4.224e-208 658.0
HKD1_k127_3154655_3 Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 580.0
HKD1_k127_3154655_4 PFAM membrane bound O-acyl transferase MBOAT K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 478.0
HKD1_k127_3154655_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 443.0
HKD1_k127_3154655_6 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 430.0
HKD1_k127_3154655_7 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 376.0
HKD1_k127_3154655_8 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 331.0
HKD1_k127_3154655_9 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000156 253.0
HKD1_k127_3167989_0 FAD linked oxidases, C-terminal domain - - - 0.0 1254.0
HKD1_k127_3167989_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1158.0
HKD1_k127_3167989_10 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 393.0
HKD1_k127_3167989_11 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 364.0
HKD1_k127_3167989_12 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 342.0
HKD1_k127_3167989_13 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 319.0
HKD1_k127_3167989_14 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 317.0
HKD1_k127_3167989_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 315.0
HKD1_k127_3167989_16 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 296.0
HKD1_k127_3167989_17 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005054 269.0
HKD1_k127_3167989_18 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005403 246.0
HKD1_k127_3167989_19 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000006691 165.0
HKD1_k127_3167989_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1061.0
HKD1_k127_3167989_20 - - - - 0.0000000000000000000000000000000000000009867 159.0
HKD1_k127_3167989_21 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000001811 145.0
HKD1_k127_3167989_22 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000171 139.0
HKD1_k127_3167989_23 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000005852 122.0
HKD1_k127_3167989_24 - - - - 0.00000000000000000000000069 121.0
HKD1_k127_3167989_25 Transglycosylase associated protein - - - 0.000000000000000000001838 102.0
HKD1_k127_3167989_26 Protein of unknown function (DUF2782) - - - 0.00000000000000004017 85.0
HKD1_k127_3167989_27 Predicted integral membrane protein (DUF2269) - - - 0.000000000001281 69.0
HKD1_k127_3167989_28 Predicted integral membrane protein (DUF2269) - - - 0.000000000006101 72.0
HKD1_k127_3167989_29 Protein of unknown function (DUF2726) - - - 0.000558 50.0
HKD1_k127_3167989_3 Helicase K03657 - 3.6.4.12 4.78e-294 923.0
HKD1_k127_3167989_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.068e-285 882.0
HKD1_k127_3167989_5 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.046e-199 633.0
HKD1_k127_3167989_6 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 633.0
HKD1_k127_3167989_7 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 606.0
HKD1_k127_3167989_8 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 537.0
HKD1_k127_3167989_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 517.0
HKD1_k127_3175688_0 5-oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1279.0
HKD1_k127_3175688_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001107 266.0
HKD1_k127_3175688_2 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000003921 213.0
HKD1_k127_3189666_0 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000005773 187.0
HKD1_k127_3189666_1 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000001955 174.0
HKD1_k127_3189666_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000002105 142.0
HKD1_k127_3189666_3 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000001601 91.0
HKD1_k127_3193838_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 560.0
HKD1_k127_3193838_1 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000001257 145.0
HKD1_k127_3193838_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000002432 91.0
HKD1_k127_3193838_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000001115 62.0
HKD1_k127_3195271_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1466.0
HKD1_k127_3195271_1 Serine aminopeptidase, S33 - - - 1.039e-211 670.0
HKD1_k127_3195271_10 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000009308 76.0
HKD1_k127_3195271_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 400.0
HKD1_k127_3195271_3 Putative threonine/serine exporter - - - 0.00000000000000000000000000000000000000000000000000004121 196.0
HKD1_k127_3195271_4 - - - - 0.00000000000000000000000000000000000000000003591 164.0
HKD1_k127_3195271_5 Na+/H+ ion antiporter subunit - - - 0.0000000000000000000000000000000000000000001556 173.0
HKD1_k127_3195271_6 - - - - 0.00000000000000000000000000000000000000005225 160.0
HKD1_k127_3195271_7 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000001509 136.0
HKD1_k127_3195271_8 Domain of unknown function (DUF4040) - - - 0.000000000000000000000000000000008072 136.0
HKD1_k127_3195271_9 - - - - 0.0000000000000000000001081 101.0
HKD1_k127_3208444_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 304.0
HKD1_k127_3208444_1 - - - - 0.0000000000000000000000000000000000000000000000005553 190.0
HKD1_k127_3208444_2 nuclease K01174 - 3.1.31.1 0.00000000000000000000000000000000000000002104 158.0
HKD1_k127_3208444_3 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000003352 150.0
HKD1_k127_3208444_4 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000011 149.0
HKD1_k127_3256411_0 Malic enzyme K00029 - 1.1.1.40 0.0 1074.0
HKD1_k127_3256411_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 2.786e-310 962.0
HKD1_k127_3256411_10 subunit of a heme lyase K02200 - - 0.0000003468 55.0
HKD1_k127_3256411_2 Belongs to the peptidase S16 family - - - 6.401e-254 808.0
HKD1_k127_3256411_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 361.0
HKD1_k127_3256411_4 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003848 254.0
HKD1_k127_3256411_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000001381 253.0
HKD1_k127_3256411_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
HKD1_k127_3256411_7 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000003112 177.0
HKD1_k127_3256411_8 Protein of unknown function (DUF504) - - - 0.000000000000000000000000007332 113.0
HKD1_k127_3256411_9 AMP binding - - - 0.000000000002105 80.0
HKD1_k127_3263976_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.213e-202 644.0
HKD1_k127_3263976_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 402.0
HKD1_k127_3263976_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004517 243.0
HKD1_k127_3263976_3 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000647 211.0
HKD1_k127_3269_0 binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 416.0
HKD1_k127_3269_1 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 388.0
HKD1_k127_3269_2 taurine ABC transporter K15551 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004436 274.0
HKD1_k127_3269_3 COG1226 Kef-type K transport systems K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.0000000000007049 81.0
HKD1_k127_3276572_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 483.0
HKD1_k127_3276572_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 307.0
HKD1_k127_3276572_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000001434 158.0
HKD1_k127_3276572_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000002086 153.0
HKD1_k127_3276572_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000004175 119.0
HKD1_k127_3276572_13 Ribosomal protein L30 K02907 - - 0.0000000000001395 80.0
HKD1_k127_3276572_14 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000001121 70.0
HKD1_k127_3276572_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001956 274.0
HKD1_k127_3276572_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009419 255.0
HKD1_k127_3276572_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007551 247.0
HKD1_k127_3276572_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000004405 220.0
HKD1_k127_3276572_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000001486 211.0
HKD1_k127_3276572_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000347 211.0
HKD1_k127_3276572_8 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000001314 195.0
HKD1_k127_3276572_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000001059 160.0
HKD1_k127_3281765_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 2.552e-301 947.0
HKD1_k127_3281765_1 Thi4 family - - - 8.801e-219 695.0
HKD1_k127_3281765_10 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 298.0
HKD1_k127_3281765_11 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 287.0
HKD1_k127_3281765_12 Disulfide bond isomerase protein N-terminus K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000007099 244.0
HKD1_k127_3281765_13 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000269 198.0
HKD1_k127_3281765_14 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000009765 186.0
HKD1_k127_3281765_15 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000006779 194.0
HKD1_k127_3281765_16 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000003142 174.0
HKD1_k127_3281765_17 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001003 157.0
HKD1_k127_3281765_18 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000007369 145.0
HKD1_k127_3281765_19 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000001463 129.0
HKD1_k127_3281765_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.377e-202 642.0
HKD1_k127_3281765_20 - - - - 0.00000000000000000000000003396 125.0
HKD1_k127_3281765_21 Protein of unknown function (DUF4019) - - - 0.00000000000003726 85.0
HKD1_k127_3281765_22 - - - - 0.00005484 55.0
HKD1_k127_3281765_23 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00005983 53.0
HKD1_k127_3281765_3 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 503.0
HKD1_k127_3281765_4 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 472.0
HKD1_k127_3281765_5 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 419.0
HKD1_k127_3281765_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 367.0
HKD1_k127_3281765_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 315.0
HKD1_k127_3281765_8 Ubiquinone biosynthesis hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 326.0
HKD1_k127_3281765_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 282.0
HKD1_k127_3285368_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 601.0
HKD1_k127_3285368_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 435.0
HKD1_k127_3285368_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 414.0
HKD1_k127_3285368_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000003595 182.0
HKD1_k127_3285368_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000001449 176.0
HKD1_k127_3322317_0 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 569.0
HKD1_k127_3322317_1 - - - - 0.000000000000000000000000000000000007446 143.0
HKD1_k127_3322317_2 FAD linked oxidases, C-terminal domain K18930 - - 0.000000000000000001351 86.0
HKD1_k127_3337985_0 Mammalian cell entry related domain protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002086 262.0
HKD1_k127_3337985_1 ABC transporter K02065 - - 0.000000000000000000000000001699 112.0
HKD1_k127_3338773_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1737.0
HKD1_k127_3338773_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1078.0
HKD1_k127_3338773_10 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 362.0
HKD1_k127_3338773_11 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 277.0
HKD1_k127_3338773_12 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001328 275.0
HKD1_k127_3338773_13 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000003071 261.0
HKD1_k127_3338773_14 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001432 225.0
HKD1_k127_3338773_15 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000008108 238.0
HKD1_k127_3338773_16 Cupin 2, conserved barrel domain protein K00450,K00971,K09988,K11312 - 1.13.11.4,2.7.7.13,5.3.1.15 0.00000000000000000000000000000000000000000000000006276 197.0
HKD1_k127_3338773_17 TIGRFAM yecA family protein K07039 - - 0.00000000000000000000000000000000008747 145.0
HKD1_k127_3338773_18 - - - - 0.0000000000000000000000000000001188 128.0
HKD1_k127_3338773_19 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000025 100.0
HKD1_k127_3338773_2 Domain of unknown function (DUF2088) - - - 1.482e-198 625.0
HKD1_k127_3338773_20 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000007626 78.0
HKD1_k127_3338773_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 527.0
HKD1_k127_3338773_4 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 518.0
HKD1_k127_3338773_5 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 501.0
HKD1_k127_3338773_6 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 427.0
HKD1_k127_3338773_7 OHCU decarboxylase K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 394.0
HKD1_k127_3338773_8 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 376.0
HKD1_k127_3338773_9 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 356.0
HKD1_k127_3339138_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1547.0
HKD1_k127_3339138_1 RNA secondary structure unwinding K03724 - - 3.628e-295 932.0
HKD1_k127_3339138_10 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 400.0
HKD1_k127_3339138_11 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 364.0
HKD1_k127_3339138_12 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 332.0
HKD1_k127_3339138_13 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 302.0
HKD1_k127_3339138_14 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004274 267.0
HKD1_k127_3339138_15 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000642 224.0
HKD1_k127_3339138_16 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000001314 222.0
HKD1_k127_3339138_17 protein import - - - 0.00000000000000000000000002415 123.0
HKD1_k127_3339138_18 Subtilase family - - - 0.000000000000001148 90.0
HKD1_k127_3339138_19 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000001149 73.0
HKD1_k127_3339138_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.078e-258 812.0
HKD1_k127_3339138_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 544.0
HKD1_k127_3339138_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 469.0
HKD1_k127_3339138_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 460.0
HKD1_k127_3339138_6 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 456.0
HKD1_k127_3339138_7 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 469.0
HKD1_k127_3339138_8 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 463.0
HKD1_k127_3339138_9 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 456.0
HKD1_k127_3342410_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 2.998e-267 839.0
HKD1_k127_3342410_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.337e-253 791.0
HKD1_k127_3342410_10 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000005305 247.0
HKD1_k127_3342410_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000000000002504 212.0
HKD1_k127_3342410_12 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000000000004542 202.0
HKD1_k127_3342410_13 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000325 153.0
HKD1_k127_3342410_14 Pathogenicity locus - - - 0.0000000000000000000000006726 121.0
HKD1_k127_3342410_15 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.000000000000000000000001776 111.0
HKD1_k127_3342410_16 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000001304 59.0
HKD1_k127_3342410_2 Phosphoesterase family - - - 3.579e-196 640.0
HKD1_k127_3342410_3 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 550.0
HKD1_k127_3342410_4 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 501.0
HKD1_k127_3342410_5 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 439.0
HKD1_k127_3342410_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 415.0
HKD1_k127_3342410_7 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 374.0
HKD1_k127_3342410_8 DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 313.0
HKD1_k127_3342410_9 Damage-inducible protein DinB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
HKD1_k127_3343127_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 450.0
HKD1_k127_3343127_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 446.0
HKD1_k127_3343127_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 398.0
HKD1_k127_3343127_3 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
HKD1_k127_3343127_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000004057 211.0
HKD1_k127_3343127_5 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000003758 183.0
HKD1_k127_3343127_6 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000154 192.0
HKD1_k127_3343127_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000144 126.0
HKD1_k127_3343127_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000001194 128.0
HKD1_k127_3345243_0 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 2.245e-209 657.0
HKD1_k127_3345243_1 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003701 274.0
HKD1_k127_3345243_2 LysE type translocator K05834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001916 264.0
HKD1_k127_3345243_3 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.0000000000000000000000000000000000000001203 151.0
HKD1_k127_3354539_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 551.0
HKD1_k127_3354539_1 Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 431.0
HKD1_k127_3354539_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 395.0
HKD1_k127_3354539_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 327.0
HKD1_k127_3354539_4 PFAM DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000002904 215.0
HKD1_k127_3354539_5 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000002864 211.0
HKD1_k127_3354539_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000004761 175.0
HKD1_k127_3354539_7 Late embryogenesis abundant protein - - - 0.00006657 55.0
HKD1_k127_3357419_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1148.0
HKD1_k127_3357419_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 7.956e-292 908.0
HKD1_k127_3357419_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 559.0
HKD1_k127_3357419_3 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 352.0
HKD1_k127_3357419_4 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000001418 185.0
HKD1_k127_3357419_5 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000001227 179.0
HKD1_k127_3357419_6 membrane - - - 0.0000000000000000000000000000001192 127.0
HKD1_k127_3357419_7 - - - - 0.00000000000000003361 83.0
HKD1_k127_3361790_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.146e-286 892.0
HKD1_k127_3361790_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.744e-271 851.0
HKD1_k127_3361790_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 403.0
HKD1_k127_3361790_11 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 399.0
HKD1_k127_3361790_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 391.0
HKD1_k127_3361790_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 381.0
HKD1_k127_3361790_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 355.0
HKD1_k127_3361790_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 327.0
HKD1_k127_3361790_16 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 308.0
HKD1_k127_3361790_17 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 302.0
HKD1_k127_3361790_18 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 301.0
HKD1_k127_3361790_19 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 273.0
HKD1_k127_3361790_2 glutaminyl-tRNA K01886 - 6.1.1.18 1.278e-258 811.0
HKD1_k127_3361790_20 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000001359 249.0
HKD1_k127_3361790_21 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001164 244.0
HKD1_k127_3361790_22 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000001465 210.0
HKD1_k127_3361790_23 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000003474 190.0
HKD1_k127_3361790_24 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000002015 197.0
HKD1_k127_3361790_25 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000000000001814 162.0
HKD1_k127_3361790_26 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000002563 156.0
HKD1_k127_3361790_27 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000004912 144.0
HKD1_k127_3361790_28 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000009202 148.0
HKD1_k127_3361790_29 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000000001594 106.0
HKD1_k127_3361790_3 Transmembrane secretion effector - - - 1.747e-246 784.0
HKD1_k127_3361790_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 1.772e-203 640.0
HKD1_k127_3361790_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 616.0
HKD1_k127_3361790_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 580.0
HKD1_k127_3361790_7 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 553.0
HKD1_k127_3361790_8 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 550.0
HKD1_k127_3361790_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 476.0
HKD1_k127_3371072_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 411.0
HKD1_k127_3371072_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 340.0
HKD1_k127_3402758_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 332.0
HKD1_k127_3402758_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000004396 265.0
HKD1_k127_3402758_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000001407 237.0
HKD1_k127_3415395_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1108.0
HKD1_k127_3415395_1 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 537.0
HKD1_k127_3415395_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 341.0
HKD1_k127_3415395_11 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007484 291.0
HKD1_k127_3415395_12 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004436 256.0
HKD1_k127_3415395_13 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000006917 187.0
HKD1_k127_3415395_14 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000004163 137.0
HKD1_k127_3415395_15 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000002212 130.0
HKD1_k127_3415395_16 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000003678 111.0
HKD1_k127_3415395_2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 524.0
HKD1_k127_3415395_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 520.0
HKD1_k127_3415395_4 aminotransferase K00821,K00840 GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006553,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 516.0
HKD1_k127_3415395_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 516.0
HKD1_k127_3415395_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 423.0
HKD1_k127_3415395_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 399.0
HKD1_k127_3415395_8 Arginine N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 392.0
HKD1_k127_3415395_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 359.0
HKD1_k127_3429768_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 428.0
HKD1_k127_3429768_1 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002626 216.0
HKD1_k127_3429768_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000002294 176.0
HKD1_k127_3451542_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 508.0
HKD1_k127_3451542_1 Methionine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 505.0
HKD1_k127_3451542_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000003035 233.0
HKD1_k127_3478706_0 oxidoreductase activity - - - 1.576e-217 710.0
HKD1_k127_3478706_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 592.0
HKD1_k127_3478706_2 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002447 262.0
HKD1_k127_3478706_3 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000002496 184.0
HKD1_k127_3478706_4 - - - - 0.0000000000000000000000000003006 119.0
HKD1_k127_3478706_5 Belongs to the DapA family K01714,K13876 - 4.2.1.43,4.3.3.7 0.00000000001242 77.0
HKD1_k127_3504205_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 561.0
HKD1_k127_3504205_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 548.0
HKD1_k127_3504205_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000291 214.0
HKD1_k127_3504205_3 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000367 124.0
HKD1_k127_3504205_4 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 0.000000001687 67.0
HKD1_k127_3526924_0 ABC transporter substrate-binding protein K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 612.0
HKD1_k127_3526924_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 486.0
HKD1_k127_3526924_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 444.0
HKD1_k127_3526924_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 418.0
HKD1_k127_3526924_4 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 372.0
HKD1_k127_3526924_5 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 393.0
HKD1_k127_3526924_6 MORN repeat protein - - - 0.000002395 57.0
HKD1_k127_3527675_0 4Fe-4S dicluster domain - - - 9.383e-273 854.0
HKD1_k127_3527675_1 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 292.0
HKD1_k127_3527675_2 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000001245 199.0
HKD1_k127_3560861_0 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 609.0
HKD1_k127_3560861_1 PFAM fumarylacetoacetate (FAA) hydrolase K16856 - 4.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 409.0
HKD1_k127_3560861_2 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 419.0
HKD1_k127_3560861_3 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 324.0
HKD1_k127_3560861_4 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002284 265.0
HKD1_k127_3560861_5 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002159 246.0
HKD1_k127_3560861_6 Prolyl oligopeptidase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000302 215.0
HKD1_k127_3560861_7 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000007071 216.0
HKD1_k127_3560861_8 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000292 109.0
HKD1_k127_3625765_0 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 529.0
HKD1_k127_3625765_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 461.0
HKD1_k127_3625765_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004096 286.0
HKD1_k127_3625765_3 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000004542 202.0
HKD1_k127_3625765_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000003821 192.0
HKD1_k127_3672992_0 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 2.874e-216 677.0
HKD1_k127_3672992_1 homoserine dehydrogenase K00003 - 1.1.1.3 1.275e-205 649.0
HKD1_k127_3672992_2 Threonine synthase K01733 - 4.2.3.1 4.185e-204 646.0
HKD1_k127_3672992_3 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 409.0
HKD1_k127_3672992_4 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 374.0
HKD1_k127_3672992_5 Aminotransferase K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 340.0
HKD1_k127_3672992_6 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 333.0
HKD1_k127_3672992_7 Peptidase C13 family - - - 0.000000000000000000000000000000000000000001935 173.0
HKD1_k127_3701114_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 4.168e-217 686.0
HKD1_k127_3701114_1 Belongs to the HypD family K04654 - - 3.353e-199 634.0
HKD1_k127_3701114_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 556.0
HKD1_k127_3701114_3 Belongs to the enoyl-CoA hydratase isomerase family K19640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 345.0
HKD1_k127_3701114_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000000001697 118.0
HKD1_k127_38252_0 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000712 256.0
HKD1_k127_38252_1 T4-like virus tail tube protein gp19 - - - 0.0000000000000000002864 96.0
HKD1_k127_38252_2 ATPase involved in DNA repair - - - 0.000000002933 68.0
HKD1_k127_39138_0 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1121.0
HKD1_k127_39138_1 Tricorn protease homolog K08676 - - 0.0 1090.0
HKD1_k127_39138_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 469.0
HKD1_k127_39138_11 helix_turn _helix lactose operon repressor K06145 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 438.0
HKD1_k127_39138_12 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 351.0
HKD1_k127_39138_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 282.0
HKD1_k127_39138_14 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004457 292.0
HKD1_k127_39138_15 Belongs to the HpcH HpaI aldolase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001422 281.0
HKD1_k127_39138_16 Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002786 285.0
HKD1_k127_39138_17 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008403 287.0
HKD1_k127_39138_18 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008555 259.0
HKD1_k127_39138_19 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
HKD1_k127_39138_2 Belongs to the glycosyl hydrolase 13 family K02438 - 3.2.1.196 1.131e-287 915.0
HKD1_k127_39138_20 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000005939 195.0
HKD1_k127_39138_21 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000000001804 192.0
HKD1_k127_39138_22 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000009403 170.0
HKD1_k127_39138_23 protein conserved in bacteria K09796 - - 0.000000000000000000000000000000000000001392 154.0
HKD1_k127_39138_24 TraB family K09973 - - 0.000000000000000000000000000000000000008745 162.0
HKD1_k127_39138_25 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000006673 124.0
HKD1_k127_39138_26 Anaerobic ribonucleoside-triphosphate reductase - - - 0.0000000000000000000003924 98.0
HKD1_k127_39138_27 Protein of unknown function (DUF3300) - - - 0.00000000000000000005997 92.0
HKD1_k127_39138_28 membrane - - - 0.0000001382 63.0
HKD1_k127_39138_3 Tripartite tricarboxylate transporter TctA family K07793 - - 1.966e-243 759.0
HKD1_k127_39138_4 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 1.719e-238 743.0
HKD1_k127_39138_5 oligoendopeptidase F K08602 - - 9.832e-221 700.0
HKD1_k127_39138_6 protein conserved in bacteria K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 517.0
HKD1_k127_39138_7 ATPase (AAA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 485.0
HKD1_k127_39138_8 ABC-type dipeptide transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 500.0
HKD1_k127_39138_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 470.0
HKD1_k127_396444_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 2.746e-305 943.0
HKD1_k127_4012507_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 579.0
HKD1_k127_4012507_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 500.0
HKD1_k127_4012507_10 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000003473 171.0
HKD1_k127_4012507_11 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000001148 147.0
HKD1_k127_4012507_12 HutD K09975 - - 0.0000000000000000000000000000000000002622 148.0
HKD1_k127_4012507_13 Aspartyl protease - - - 0.000000000000000000000000000001534 138.0
HKD1_k127_4012507_14 Putative prokaryotic signal transducing protein - - - 0.00000000000000005255 93.0
HKD1_k127_4012507_2 Catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 477.0
HKD1_k127_4012507_3 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 464.0
HKD1_k127_4012507_4 Pfam Binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 409.0
HKD1_k127_4012507_5 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 375.0
HKD1_k127_4012507_6 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 324.0
HKD1_k127_4012507_7 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 300.0
HKD1_k127_4012507_8 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001486 274.0
HKD1_k127_4012507_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000009486 185.0
HKD1_k127_4029028_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1262.0
HKD1_k127_4029028_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 7.992e-319 1003.0
HKD1_k127_4029028_10 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 360.0
HKD1_k127_4029028_11 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 307.0
HKD1_k127_4029028_12 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 310.0
HKD1_k127_4029028_13 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 324.0
HKD1_k127_4029028_14 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006562 276.0
HKD1_k127_4029028_15 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000983 247.0
HKD1_k127_4029028_16 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000001541 246.0
HKD1_k127_4029028_17 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
HKD1_k127_4029028_18 Permease of the major facilitator superfamily K08369 - - 0.0000000000000000000000000000000000000000000000000000004972 214.0
HKD1_k127_4029028_19 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000000000000000000000000000000000000000000000000008613 203.0
HKD1_k127_4029028_2 molybdopterin cofactor binding K08352 - 1.8.5.5 5.291e-316 984.0
HKD1_k127_4029028_20 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000004541 178.0
HKD1_k127_4029028_21 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000001163 170.0
HKD1_k127_4029028_22 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000002183 165.0
HKD1_k127_4029028_23 Thioesterase - - - 0.0000000000000000000000000000000000000000004531 166.0
HKD1_k127_4029028_24 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000008977 163.0
HKD1_k127_4029028_25 transcriptional regulator - - - 0.00000000000000000000000000000000000001379 152.0
HKD1_k127_4029028_26 ferredoxin - - - 0.0000000000000000000000000000000000005578 144.0
HKD1_k127_4029028_27 Cobalt uptake substrate-specific transmembrane region - - - 0.0000000000000000000000000000542 128.0
HKD1_k127_4029028_28 Invasion gene expression up-regulator, SirB - - - 0.00000000000000000001141 99.0
HKD1_k127_4029028_29 Hemerythrin HHE cation binding domain - - - 0.000000000001899 77.0
HKD1_k127_4029028_3 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 608.0
HKD1_k127_4029028_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 607.0
HKD1_k127_4029028_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 583.0
HKD1_k127_4029028_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 430.0
HKD1_k127_4029028_7 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 426.0
HKD1_k127_4029028_8 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 380.0
HKD1_k127_4029028_9 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 357.0
HKD1_k127_4053217_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1317.0
HKD1_k127_4053217_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 540.0
HKD1_k127_4053217_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 456.0
HKD1_k127_4053217_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 288.0
HKD1_k127_4053217_4 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 288.0
HKD1_k127_4053217_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008846 274.0
HKD1_k127_4061013_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 571.0
HKD1_k127_4061013_1 PFAM Transketolase central region K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 546.0
HKD1_k127_4061013_2 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 529.0
HKD1_k127_4061013_3 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 422.0
HKD1_k127_4061013_4 PFAM ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 328.0
HKD1_k127_4061013_5 Iron permease K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004294 266.0
HKD1_k127_4061013_6 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000006061 255.0
HKD1_k127_4061013_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000533 209.0
HKD1_k127_4061013_8 PFAM globin K06886 - - 0.0000000000000000000000000000000000000002901 171.0
HKD1_k127_4061013_9 Cupredoxin-like domain - - - 0.00000000000000000000003104 102.0
HKD1_k127_4069148_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 409.0
HKD1_k127_4069148_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 374.0
HKD1_k127_4069230_0 ABC transporter K06020 - 3.6.3.25 3.659e-293 906.0
HKD1_k127_4069230_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 6.021e-269 847.0
HKD1_k127_4069230_10 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 458.0
HKD1_k127_4069230_11 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 403.0
HKD1_k127_4069230_12 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
HKD1_k127_4069230_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 304.0
HKD1_k127_4069230_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 293.0
HKD1_k127_4069230_15 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 264.0
HKD1_k127_4069230_16 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000004148 205.0
HKD1_k127_4069230_17 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000003246 187.0
HKD1_k127_4069230_18 shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000001323 159.0
HKD1_k127_4069230_19 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000004835 141.0
HKD1_k127_4069230_2 Belongs to the glutaminase family K01425 - 3.5.1.2 8.178e-226 715.0
HKD1_k127_4069230_20 Glu-tRNAGln amidotransferase C subunit - - - 0.0000000000000000000000000000007927 125.0
HKD1_k127_4069230_21 PFAM HNH endonuclease K07451 - - 0.0000000000000000000005898 104.0
HKD1_k127_4069230_22 Domain of unknown function (DUF4124) - - - 0.000000000000000000008623 107.0
HKD1_k127_4069230_23 - - - - 0.000000006274 58.0
HKD1_k127_4069230_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.699e-220 694.0
HKD1_k127_4069230_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.169e-208 661.0
HKD1_k127_4069230_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 7.745e-199 634.0
HKD1_k127_4069230_6 ABC transporter K06158 - - 1.303e-194 625.0
HKD1_k127_4069230_7 Rod shape-determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 612.0
HKD1_k127_4069230_8 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 509.0
HKD1_k127_4069230_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 471.0
HKD1_k127_4071357_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 572.0
HKD1_k127_4071357_1 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 518.0
HKD1_k127_4071357_10 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 313.0
HKD1_k127_4071357_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001078 216.0
HKD1_k127_4071357_12 FR47-like protein - - - 0.000000000000000000000000000000000000003428 153.0
HKD1_k127_4071357_13 Small multidrug resistance - - - 0.0000000000000000000000000000000000003129 149.0
HKD1_k127_4071357_14 Binding-protein-dependent transport system inner membrane component - - - 0.000000000009171 71.0
HKD1_k127_4071357_2 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 465.0
HKD1_k127_4071357_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 460.0
HKD1_k127_4071357_4 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 428.0
HKD1_k127_4071357_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 420.0
HKD1_k127_4071357_6 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 413.0
HKD1_k127_4071357_7 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 393.0
HKD1_k127_4071357_8 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 401.0
HKD1_k127_4071357_9 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 374.0
HKD1_k127_4102490_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.108e-297 926.0
HKD1_k127_4102490_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.317e-207 664.0
HKD1_k127_4102490_10 amine dehydrogenase activity - - - 0.0000000001443 76.0
HKD1_k127_4102490_11 Domain of unknown function (DUF4118) - - - 0.000000002334 69.0
HKD1_k127_4102490_12 regulator K07684 - - 0.000000004605 60.0
HKD1_k127_4102490_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 4.491e-199 634.0
HKD1_k127_4102490_3 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 546.0
HKD1_k127_4102490_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 511.0
HKD1_k127_4102490_5 PFAM EAL domain, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 294.0
HKD1_k127_4102490_6 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 319.0
HKD1_k127_4102490_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000006626 215.0
HKD1_k127_4102490_8 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000003091 113.0
HKD1_k127_4145167_0 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 548.0
HKD1_k127_4145167_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000001281 134.0
HKD1_k127_4153921_0 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 295.0
HKD1_k127_4153921_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001989 247.0
HKD1_k127_4153921_2 MazG-like family - - - 0.00000000000000000000000000000003231 134.0
HKD1_k127_4153921_3 Cytochrome c - - - 0.0000000000000000000003934 99.0
HKD1_k127_4153921_4 Radical SAM K04069 - 1.97.1.4 0.00000000000000000009182 89.0
HKD1_k127_4154608_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1394.0
HKD1_k127_4154608_1 Subtilase family - - - 2.08e-207 695.0
HKD1_k127_4154608_10 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000004645 139.0
HKD1_k127_4154608_11 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000005512 79.0
HKD1_k127_4154608_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 619.0
HKD1_k127_4154608_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 465.0
HKD1_k127_4154608_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 423.0
HKD1_k127_4154608_5 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 382.0
HKD1_k127_4154608_6 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001537 287.0
HKD1_k127_4154608_7 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001195 289.0
HKD1_k127_4154608_8 MaoC like domain - - - 0.0000000000000000000000000000000000000006032 163.0
HKD1_k127_4154608_9 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000001244 142.0
HKD1_k127_4158546_0 amp-dependent synthetase and ligase - - - 1.858e-232 735.0
HKD1_k127_4171545_0 Oxidoreductase family, NAD-binding Rossmann fold K19181 - 1.1.1.292 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 393.0
HKD1_k127_4171545_1 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 334.0
HKD1_k127_4171545_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 314.0
HKD1_k127_4171545_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005659 262.0
HKD1_k127_4171545_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000001386 252.0
HKD1_k127_4171545_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000004331 254.0
HKD1_k127_4171545_6 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000006021 132.0
HKD1_k127_4186803_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 7.399e-277 864.0
HKD1_k127_4186803_1 Peptidase M16 inactive domain protein K07263 - - 6.678e-270 858.0
HKD1_k127_4186803_10 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 357.0
HKD1_k127_4186803_11 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 329.0
HKD1_k127_4186803_12 inositol mono-phosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000001501 170.0
HKD1_k127_4186803_13 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000001277 149.0
HKD1_k127_4186803_2 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.902e-266 837.0
HKD1_k127_4186803_3 Extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 563.0
HKD1_k127_4186803_4 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 503.0
HKD1_k127_4186803_5 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 489.0
HKD1_k127_4186803_6 Xylose isomerase K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 448.0
HKD1_k127_4186803_7 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 430.0
HKD1_k127_4186803_8 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 431.0
HKD1_k127_4186803_9 KduI/IolB family K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 390.0
HKD1_k127_4194339_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.314e-267 830.0
HKD1_k127_4194339_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.143e-249 782.0
HKD1_k127_4194339_10 beta-hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 321.0
HKD1_k127_4194339_11 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 329.0
HKD1_k127_4194339_12 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008894 271.0
HKD1_k127_4194339_13 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 253.0
HKD1_k127_4194339_14 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HKD1_k127_4194339_15 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000000747 216.0
HKD1_k127_4194339_16 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000111 208.0
HKD1_k127_4194339_17 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000003907 215.0
HKD1_k127_4194339_18 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000009509 189.0
HKD1_k127_4194339_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000005812 186.0
HKD1_k127_4194339_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.249e-230 725.0
HKD1_k127_4194339_20 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000000003315 176.0
HKD1_k127_4194339_21 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000001692 173.0
HKD1_k127_4194339_22 - - - - 0.0000000000000000000000000000000000000007141 168.0
HKD1_k127_4194339_23 universal stress protein - - - 0.0000000000000000000000000000000000001581 146.0
HKD1_k127_4194339_24 - - - - 0.000000000000000000000000000000004367 139.0
HKD1_k127_4194339_25 PFAM RNA-binding S4 domain protein K04762 - - 0.000000000000000000000000003823 118.0
HKD1_k127_4194339_26 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000003567 105.0
HKD1_k127_4194339_27 cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000005881 76.0
HKD1_k127_4194339_28 - - - - 0.00000000001174 71.0
HKD1_k127_4194339_29 Psort location CytoplasmicMembrane, score - - - 0.000005551 58.0
HKD1_k127_4194339_3 cation transport ATPase K01533 - 3.6.3.4 2.249e-216 699.0
HKD1_k127_4194339_4 secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 612.0
HKD1_k127_4194339_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 589.0
HKD1_k127_4194339_6 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 496.0
HKD1_k127_4194339_7 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 419.0
HKD1_k127_4194339_8 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 334.0
HKD1_k127_4194339_9 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 337.0
HKD1_k127_4196029_0 AcrB/AcrD/AcrF family K03296 - - 5.707e-251 791.0
HKD1_k127_4196029_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 461.0
HKD1_k127_4196029_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001786 279.0
HKD1_k127_4196029_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000001021 220.0
HKD1_k127_4200077_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 561.0
HKD1_k127_4200077_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 481.0
HKD1_k127_4200077_2 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 486.0
HKD1_k127_4200077_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 488.0
HKD1_k127_4200077_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 383.0
HKD1_k127_4200077_5 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 389.0
HKD1_k127_4200077_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001801 265.0
HKD1_k127_4200077_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000001897 159.0
HKD1_k127_4226752_0 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 605.0
HKD1_k127_4226752_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 416.0
HKD1_k127_4226752_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002411 207.0
HKD1_k127_4226752_3 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000001522 86.0
HKD1_k127_4226752_4 Elements of external origin K07497 - - 0.000000000000000003937 89.0
HKD1_k127_4228081_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.928e-295 925.0
HKD1_k127_4228081_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 9.982e-285 887.0
HKD1_k127_4228081_10 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 337.0
HKD1_k127_4228081_11 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 332.0
HKD1_k127_4228081_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 326.0
HKD1_k127_4228081_13 TRAP transporter solute receptor TAXI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 329.0
HKD1_k127_4228081_14 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 291.0
HKD1_k127_4228081_15 response regulator K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 297.0
HKD1_k127_4228081_16 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004909 242.0
HKD1_k127_4228081_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000001717 222.0
HKD1_k127_4228081_18 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000001814 211.0
HKD1_k127_4228081_19 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000004394 194.0
HKD1_k127_4228081_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 3.177e-208 666.0
HKD1_k127_4228081_20 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000001944 201.0
HKD1_k127_4228081_21 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000008436 188.0
HKD1_k127_4228081_22 redox protein, regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000001462 178.0
HKD1_k127_4228081_23 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000008905 185.0
HKD1_k127_4228081_24 oxidation protein K17227 - - 0.00000000000000000000000000000000000000000002808 163.0
HKD1_k127_4228081_25 intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000003896 174.0
HKD1_k127_4228081_26 Thioredoxin-like - - - 0.00000000000000000000000000000000000000001205 160.0
HKD1_k127_4228081_27 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000007689 154.0
HKD1_k127_4228081_28 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000339 152.0
HKD1_k127_4228081_29 acetyltransferase K03825 - - 0.0000000000000000000000000000002392 136.0
HKD1_k127_4228081_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 1.547e-195 612.0
HKD1_k127_4228081_30 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000004178 136.0
HKD1_k127_4228081_31 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797 - 2.5.1.16 0.0000000000000000000000009195 111.0
HKD1_k127_4228081_32 - - - - 0.0000000000000000000000009975 120.0
HKD1_k127_4228081_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 578.0
HKD1_k127_4228081_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 492.0
HKD1_k127_4228081_6 NADP oxidoreductase coenzyme F420-dependent K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 419.0
HKD1_k127_4228081_7 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 393.0
HKD1_k127_4228081_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 383.0
HKD1_k127_4228081_9 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 377.0
HKD1_k127_427271_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 2.391e-314 978.0
HKD1_k127_427271_1 PfkB domain protein K03338 - 2.7.1.92 1.039e-295 925.0
HKD1_k127_427271_2 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 473.0
HKD1_k127_427271_3 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 450.0
HKD1_k127_427271_4 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005189 268.0
HKD1_k127_4318693_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1147.0
HKD1_k127_4318693_1 Transport of potassium into the cell K03549 - - 2.702e-244 769.0
HKD1_k127_4318693_10 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 376.0
HKD1_k127_4318693_11 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 356.0
HKD1_k127_4318693_12 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 349.0
HKD1_k127_4318693_13 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 337.0
HKD1_k127_4318693_14 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 316.0
HKD1_k127_4318693_15 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 313.0
HKD1_k127_4318693_16 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 304.0
HKD1_k127_4318693_17 PFAM Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001643 292.0
HKD1_k127_4318693_18 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001856 287.0
HKD1_k127_4318693_19 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002219 277.0
HKD1_k127_4318693_2 Dynamin family - - - 1.006e-223 711.0
HKD1_k127_4318693_20 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 241.0
HKD1_k127_4318693_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000003484 228.0
HKD1_k127_4318693_22 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000006966 227.0
HKD1_k127_4318693_23 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000793 222.0
HKD1_k127_4318693_24 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000001567 173.0
HKD1_k127_4318693_25 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000008144 169.0
HKD1_k127_4318693_26 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000002321 148.0
HKD1_k127_4318693_27 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000001434 162.0
HKD1_k127_4318693_28 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000002973 121.0
HKD1_k127_4318693_29 Protein of unknown function (DUF2905) - - - 0.000000000000000000000001011 104.0
HKD1_k127_4318693_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 628.0
HKD1_k127_4318693_30 Lipocalin-like domain - - - 0.000000000000000003572 85.0
HKD1_k127_4318693_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 599.0
HKD1_k127_4318693_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 504.0
HKD1_k127_4318693_6 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 425.0
HKD1_k127_4318693_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 405.0
HKD1_k127_4318693_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 400.0
HKD1_k127_4318693_9 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 373.0
HKD1_k127_4344291_0 solute:proton antiporter activity K03455,K07058 - - 1.144e-211 676.0
HKD1_k127_4344291_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.908e-208 662.0
HKD1_k127_4344291_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 521.0
HKD1_k127_4344291_3 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 448.0
HKD1_k127_4344291_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 417.0
HKD1_k127_4344291_5 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 320.0
HKD1_k127_4344291_6 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005142 271.0
HKD1_k127_4344291_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000004402 261.0
HKD1_k127_4404850_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.675e-268 839.0
HKD1_k127_4404850_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000267 72.0
HKD1_k127_4477443_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1262.0
HKD1_k127_4526606_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 292.0
HKD1_k127_4526606_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000004615 228.0
HKD1_k127_4526606_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000002089 223.0
HKD1_k127_4526606_3 Phosphopantetheine attachment site - - - 0.0000002702 63.0
HKD1_k127_4633039_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 587.0
HKD1_k127_4633039_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 439.0
HKD1_k127_4633039_10 Rubrerythrin - - - 0.000000000000000000000000000000009904 136.0
HKD1_k127_4633039_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 428.0
HKD1_k127_4633039_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 394.0
HKD1_k127_4633039_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 371.0
HKD1_k127_4633039_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 377.0
HKD1_k127_4633039_6 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 331.0
HKD1_k127_4633039_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 331.0
HKD1_k127_4633039_8 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 300.0
HKD1_k127_4633039_9 thioesterase K01075 - 3.1.2.23 0.0000000000000000000000000000000000000003996 164.0
HKD1_k127_47058_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.828e-209 660.0
HKD1_k127_47058_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.11e-209 664.0
HKD1_k127_47058_10 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002416 239.0
HKD1_k127_47058_11 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000007397 207.0
HKD1_k127_47058_12 Cell division protein ZapA K09888 - - 0.0000000000000000001069 97.0
HKD1_k127_47058_13 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000002675 88.0
HKD1_k127_47058_14 - - - - 0.00000415 51.0
HKD1_k127_47058_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 573.0
HKD1_k127_47058_3 Transcriptional regulator K03603,K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 475.0
HKD1_k127_47058_4 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 411.0
HKD1_k127_47058_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 325.0
HKD1_k127_47058_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 324.0
HKD1_k127_47058_7 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000001001 261.0
HKD1_k127_47058_8 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 266.0
HKD1_k127_47058_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000172 252.0
HKD1_k127_4784918_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 3.123e-309 973.0
HKD1_k127_4784918_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.947e-229 717.0
HKD1_k127_4784918_10 Acyl-ACP thioesterase - - - 0.00000000000000000000000000000000006261 149.0
HKD1_k127_4784918_11 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000009202 119.0
HKD1_k127_4784918_12 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000002399 135.0
HKD1_k127_4784918_13 Colicin V production K03558 - - 0.0000000000000000000000000003843 121.0
HKD1_k127_4784918_14 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000002387 105.0
HKD1_k127_4784918_15 protein conserved in bacteria K03749 - - 0.0000000002863 62.0
HKD1_k127_4784918_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 580.0
HKD1_k127_4784918_3 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001791 284.0
HKD1_k127_4784918_4 arylamine N-acetyltransferase activity K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000005632 273.0
HKD1_k127_4784918_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002169 256.0
HKD1_k127_4784918_6 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000006717 225.0
HKD1_k127_4784918_7 Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000003855 227.0
HKD1_k127_4784918_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001641 201.0
HKD1_k127_4784918_9 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000888 169.0
HKD1_k127_5038305_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1324.0
HKD1_k127_5038305_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.611e-299 925.0
HKD1_k127_5038305_10 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 433.0
HKD1_k127_5038305_11 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 427.0
HKD1_k127_5038305_12 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 322.0
HKD1_k127_5038305_13 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
HKD1_k127_5038305_14 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000002063 270.0
HKD1_k127_5038305_15 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
HKD1_k127_5038305_16 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000412 256.0
HKD1_k127_5038305_17 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000001522 237.0
HKD1_k127_5038305_18 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000285 198.0
HKD1_k127_5038305_19 OmpA family K03286 - - 0.000000000000000000000000000000000000000000000004591 182.0
HKD1_k127_5038305_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.445e-298 939.0
HKD1_k127_5038305_20 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000008045 164.0
HKD1_k127_5038305_22 GMC oxidoreductase - - - 0.000000001717 67.0
HKD1_k127_5038305_23 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000006991 61.0
HKD1_k127_5038305_24 Type II secretion system protein C K02452 - - 0.000154 53.0
HKD1_k127_5038305_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 581.0
HKD1_k127_5038305_4 PFAM aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 512.0
HKD1_k127_5038305_5 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 496.0
HKD1_k127_5038305_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 479.0
HKD1_k127_5038305_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 464.0
HKD1_k127_5038305_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 451.0
HKD1_k127_5038305_9 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 429.0
HKD1_k127_5045866_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.307e-273 846.0
HKD1_k127_5045866_1 Protein of unknown function (DUF3141) - - - 4.603e-264 835.0
HKD1_k127_5045866_2 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 529.0
HKD1_k127_5045866_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 509.0
HKD1_k127_5045866_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 370.0
HKD1_k127_5045866_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000001355 180.0
HKD1_k127_5045866_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000006434 48.0
HKD1_k127_5055966_0 Basic membrane lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 477.0
HKD1_k127_5055966_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 383.0
HKD1_k127_5149744_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 321.0
HKD1_k127_5149744_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000005674 175.0
HKD1_k127_5149744_2 CoA-transferase - - - 0.000000000000000000000002632 102.0
HKD1_k127_5164558_0 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 608.0
HKD1_k127_5164558_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 300.0
HKD1_k127_5164558_2 CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002354 259.0
HKD1_k127_5192273_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 571.0
HKD1_k127_5192273_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 520.0
HKD1_k127_5192273_2 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 492.0
HKD1_k127_5192273_3 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 501.0
HKD1_k127_5192273_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 423.0
HKD1_k127_5192273_5 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 409.0
HKD1_k127_5192273_6 transport system K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 410.0
HKD1_k127_5192273_7 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 309.0
HKD1_k127_5192273_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000009552 196.0
HKD1_k127_5192273_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000009128 199.0
HKD1_k127_5235360_0 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 0.0 1134.0
HKD1_k127_5235360_1 AcyL-CoA dehydrogenase K06445 - - 0.0 1079.0
HKD1_k127_5235360_10 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 508.0
HKD1_k127_5235360_11 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 501.0
HKD1_k127_5235360_12 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 496.0
HKD1_k127_5235360_13 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 490.0
HKD1_k127_5235360_14 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 488.0
HKD1_k127_5235360_15 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 455.0
HKD1_k127_5235360_16 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 461.0
HKD1_k127_5235360_17 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 426.0
HKD1_k127_5235360_18 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 406.0
HKD1_k127_5235360_19 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 407.0
HKD1_k127_5235360_2 Male sterility protein - - - 1.006e-284 889.0
HKD1_k127_5235360_20 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 402.0
HKD1_k127_5235360_21 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 343.0
HKD1_k127_5235360_22 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 354.0
HKD1_k127_5235360_23 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 301.0
HKD1_k127_5235360_24 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 287.0
HKD1_k127_5235360_25 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009398 290.0
HKD1_k127_5235360_26 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002018 284.0
HKD1_k127_5235360_27 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001848 269.0
HKD1_k127_5235360_28 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004792 254.0
HKD1_k127_5235360_29 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
HKD1_k127_5235360_3 Fumarase C C-terminus K01744 - 4.3.1.1 9.257e-252 780.0
HKD1_k127_5235360_30 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000005702 237.0
HKD1_k127_5235360_31 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000006517 209.0
HKD1_k127_5235360_32 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000000000000000000002772 216.0
HKD1_k127_5235360_33 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000001255 209.0
HKD1_k127_5235360_34 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000001853 182.0
HKD1_k127_5235360_35 - - - - 0.0000000000000000000000000000000000000000000007351 185.0
HKD1_k127_5235360_36 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000009551 166.0
HKD1_k127_5235360_37 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000002233 164.0
HKD1_k127_5235360_38 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000006635 160.0
HKD1_k127_5235360_39 PGAP1-like protein - - - 0.0000000000000000000000000000000000000006915 161.0
HKD1_k127_5235360_4 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.22e-249 786.0
HKD1_k127_5235360_40 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000000004155 145.0
HKD1_k127_5235360_41 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000001399 143.0
HKD1_k127_5235360_42 - - - - 0.0000000000000000000000000000000002192 139.0
HKD1_k127_5235360_43 PFAM poly granule associated family protein - - - 0.000000000000000000000000001974 119.0
HKD1_k127_5235360_44 PFAM acyl-coA-binding protein, ACBP - - - 0.000000000000000000000002086 105.0
HKD1_k127_5235360_45 polyhydroxyalkanoic acid system protein - - - 0.0000000000007454 83.0
HKD1_k127_5235360_5 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 1.127e-242 754.0
HKD1_k127_5235360_6 Transporter, DASS family K11106,K14445 - - 6.622e-223 706.0
HKD1_k127_5235360_7 Belongs to the thiolase family K00626 - 2.3.1.9 4.549e-216 680.0
HKD1_k127_5235360_8 GMC oxidoreductase - - - 7.009e-207 662.0
HKD1_k127_5235360_9 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 559.0
HKD1_k127_5239433_0 arylsulfatase A K01130 - 3.1.6.1 2.17e-261 817.0
HKD1_k127_5239433_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 6.13e-231 728.0
HKD1_k127_5239433_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 323.0
HKD1_k127_5239433_3 response regulator - - - 0.0000000000000000000000000000000000000000000004791 176.0
HKD1_k127_5239433_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000008564 164.0
HKD1_k127_5239433_5 Bacterial transcriptional activator domain - - - 0.00000000000000005682 94.0
HKD1_k127_5239433_6 Cupin - - - 0.000000002294 58.0
HKD1_k127_5250278_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 468.0
HKD1_k127_5250278_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 394.0
HKD1_k127_5250278_2 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 356.0
HKD1_k127_5250278_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 295.0
HKD1_k127_5292677_0 Permease family K02824 - - 2.261e-209 662.0
HKD1_k127_5292677_1 Dehydratase large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 7.035e-206 667.0
HKD1_k127_5292677_10 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000001007 169.0
HKD1_k127_5292677_11 peptide chain release factor K15034 - - 0.000000000000000000000000000000000000000000004552 169.0
HKD1_k127_5292677_12 Dehydratase K13919 - 4.2.1.28 0.000000000000000000000000000000000000000003979 178.0
HKD1_k127_5292677_13 Dehydratase small subunit K06122,K13920 - 4.2.1.28,4.2.1.30 0.000000000000000000001327 103.0
HKD1_k127_5292677_14 - - - - 0.0000002852 64.0
HKD1_k127_5292677_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 599.0
HKD1_k127_5292677_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 449.0
HKD1_k127_5292677_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 473.0
HKD1_k127_5292677_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 399.0
HKD1_k127_5292677_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 351.0
HKD1_k127_5292677_7 Protein of unknown function, DUF480 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
HKD1_k127_5292677_8 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000004294 200.0
HKD1_k127_5292677_9 Aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000173 212.0
HKD1_k127_5387467_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 288.0
HKD1_k127_5387467_1 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000001492 145.0
HKD1_k127_5387467_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000001822 85.0
HKD1_k127_5394966_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2259.0
HKD1_k127_5394966_1 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 4.299e-226 772.0
HKD1_k127_5394966_10 Sporulation related domain - - - 0.000000000000000000000007071 112.0
HKD1_k127_5394966_2 TIGRFAM arginyl-tRNA synthetase K01887 - 6.1.1.19 2.6e-209 664.0
HKD1_k127_5394966_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 599.0
HKD1_k127_5394966_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 471.0
HKD1_k127_5394966_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 321.0
HKD1_k127_5394966_6 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 314.0
HKD1_k127_5394966_7 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002735 278.0
HKD1_k127_5394966_8 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000005993 192.0
HKD1_k127_5394966_9 Autotransporter beta-domain K12686 - - 0.00000000000000000000000000000004561 133.0
HKD1_k127_5448949_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 467.0
HKD1_k127_5448949_1 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 421.0
HKD1_k127_5448949_2 TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000001461 116.0
HKD1_k127_5495602_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 421.0
HKD1_k127_5495602_1 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 404.0
HKD1_k127_5495602_2 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 300.0
HKD1_k127_5495602_3 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000005619 168.0
HKD1_k127_5495602_4 TOBE domain - - - 0.0000000000000000000000356 100.0
HKD1_k127_5495602_5 5'-nucleotidase K01081 - 3.1.3.5 0.000000006571 56.0
HKD1_k127_5495602_6 Bacterial extracellular solute-binding protein K02020 - - 0.0001086 45.0
HKD1_k127_5563043_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 1281.0
HKD1_k127_5563043_1 Elongation factor G, domain IV K02355 - - 3.943e-299 932.0
HKD1_k127_5563043_10 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 516.0
HKD1_k127_5563043_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 480.0
HKD1_k127_5563043_12 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 456.0
HKD1_k127_5563043_13 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 419.0
HKD1_k127_5563043_14 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 351.0
HKD1_k127_5563043_15 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 323.0
HKD1_k127_5563043_16 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 306.0
HKD1_k127_5563043_17 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002038 269.0
HKD1_k127_5563043_18 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002653 278.0
HKD1_k127_5563043_19 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000003471 247.0
HKD1_k127_5563043_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.128e-286 899.0
HKD1_k127_5563043_20 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001631 242.0
HKD1_k127_5563043_21 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000005227 222.0
HKD1_k127_5563043_22 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000006557 233.0
HKD1_k127_5563043_23 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000001265 222.0
HKD1_k127_5563043_24 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
HKD1_k127_5563043_25 RESPONSE REGULATOR receiver K02658 - - 0.0000000000000000000000000000000000000000000000000003213 188.0
HKD1_k127_5563043_26 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000008478 185.0
HKD1_k127_5563043_27 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000002563 154.0
HKD1_k127_5563043_28 Chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000005442 157.0
HKD1_k127_5563043_29 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000006939 141.0
HKD1_k127_5563043_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.557e-275 863.0
HKD1_k127_5563043_30 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000002728 108.0
HKD1_k127_5563043_31 Tripartite tricarboxylate transporter TctB family - - - 0.000002758 59.0
HKD1_k127_5563043_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.111e-238 745.0
HKD1_k127_5563043_5 Ammonium Transporter Family K03320,K06580 - - 7.195e-218 681.0
HKD1_k127_5563043_6 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 597.0
HKD1_k127_5563043_7 Methyl-accepting chemotaxis protein K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 596.0
HKD1_k127_5563043_8 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 578.0
HKD1_k127_5563043_9 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 550.0
HKD1_k127_567481_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1264.0
HKD1_k127_567481_1 protein synthesis factor, GTP-binding K06207 - - 9.259e-296 921.0
HKD1_k127_567481_10 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K13890 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 498.0
HKD1_k127_567481_11 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 495.0
HKD1_k127_567481_12 PFAM binding-protein-dependent transport systems inner membrane component K13891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 481.0
HKD1_k127_567481_13 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 445.0
HKD1_k127_567481_14 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 415.0
HKD1_k127_567481_15 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
HKD1_k127_567481_16 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
HKD1_k127_567481_17 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 378.0
HKD1_k127_567481_18 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 359.0
HKD1_k127_567481_19 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 347.0
HKD1_k127_567481_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 7.563e-285 894.0
HKD1_k127_567481_20 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 340.0
HKD1_k127_567481_21 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 316.0
HKD1_k127_567481_22 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 295.0
HKD1_k127_567481_23 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002118 292.0
HKD1_k127_567481_24 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
HKD1_k127_567481_25 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000008177 235.0
HKD1_k127_567481_26 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000000002142 221.0
HKD1_k127_567481_27 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000006247 193.0
HKD1_k127_567481_28 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000005007 178.0
HKD1_k127_567481_29 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000009306 168.0
HKD1_k127_567481_3 Belongs to the ABC transporter superfamily K02031,K02032,K13892 - - 7.768e-285 889.0
HKD1_k127_567481_30 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000007517 146.0
HKD1_k127_567481_31 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000009574 136.0
HKD1_k127_567481_32 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000007997 134.0
HKD1_k127_567481_33 Iron-sulphur cluster assembly - - - 0.0000000000000000000000000003569 115.0
HKD1_k127_567481_4 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 5.213e-272 849.0
HKD1_k127_567481_5 ABC-type dipeptide transport system, periplasmic K02035,K13889 - - 5.033e-244 762.0
HKD1_k127_567481_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 8.499e-223 694.0
HKD1_k127_567481_7 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.671e-209 662.0
HKD1_k127_567481_8 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 605.0
HKD1_k127_567481_9 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 516.0
HKD1_k127_5694525_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.63e-279 895.0
HKD1_k127_5694525_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 1.868e-218 683.0
HKD1_k127_5694525_10 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000001207 74.0
HKD1_k127_5694525_11 Urocanase C-terminal domain - - - 0.000005945 49.0
HKD1_k127_5694525_12 Glycogen debranching enzyme - - - 0.0001942 49.0
HKD1_k127_5694525_2 Carbohydrate transport and metabolism K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 600.0
HKD1_k127_5694525_3 Catalyzes the degradation of histidine to urocanate and ammmonia K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 577.0
HKD1_k127_5694525_4 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 428.0
HKD1_k127_5694525_5 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 433.0
HKD1_k127_5694525_6 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 342.0
HKD1_k127_5694525_7 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002673 252.0
HKD1_k127_5694525_8 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007466 259.0
HKD1_k127_5694525_9 Two component transcriptional regulator, LuxR family K13041 - - 0.00000000000000000000000000000000000000000000009758 183.0
HKD1_k127_572696_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1066.0
HKD1_k127_572696_1 Histidine kinase-like ATPases - - - 8.301e-199 629.0
HKD1_k127_572696_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 430.0
HKD1_k127_572696_3 Histidine kinase K20976 - - 0.0000000000000002545 83.0
HKD1_k127_572696_5 DNA-templated transcription, initiation K03088 - - 0.00000511 51.0
HKD1_k127_572696_6 PEP-CTERM motif - - - 0.00009655 52.0
HKD1_k127_5766662_0 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 380.0
HKD1_k127_5766662_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 331.0
HKD1_k127_5766662_2 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000002512 207.0
HKD1_k127_5766662_3 CPA1 family monovalent cation H antiporter K03316 - - 0.00000000000000000000000001262 112.0
HKD1_k127_5766662_4 Mandelate racemase muconate lactonizing protein K01781,K20549 - 5.1.2.2,5.5.1.25 0.000001734 56.0
HKD1_k127_6039959_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.816e-215 676.0
HKD1_k127_6039959_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000003173 176.0
HKD1_k127_6039959_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000001615 146.0
HKD1_k127_6043676_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 556.0
HKD1_k127_6043676_1 - - - - 0.0000000000000000000000000406 109.0
HKD1_k127_6043676_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000001016 89.0
HKD1_k127_6050766_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0 1116.0
HKD1_k127_6050766_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 1.197e-250 785.0
HKD1_k127_6050766_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000006123 219.0
HKD1_k127_6050766_11 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000003067 175.0
HKD1_k127_6050766_12 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000000458 158.0
HKD1_k127_6050766_13 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000004906 172.0
HKD1_k127_6050766_14 sulfur oxidation protein (SoxY) K17226 - - 0.0000000000000000000000000000000001646 145.0
HKD1_k127_6050766_15 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000696 141.0
HKD1_k127_6050766_16 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000004467 113.0
HKD1_k127_6050766_17 Rubrerythrin - - - 0.0000000000000000001667 99.0
HKD1_k127_6050766_18 - - - - 0.0000000000000000002975 104.0
HKD1_k127_6050766_19 Glucose-regulated metallo-peptidase M90 K09933 - - 0.0000000000000008756 78.0
HKD1_k127_6050766_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 579.0
HKD1_k127_6050766_3 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 557.0
HKD1_k127_6050766_4 Acyl-CoA dehydrogenase, middle domain K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 578.0
HKD1_k127_6050766_5 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 557.0
HKD1_k127_6050766_6 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 316.0
HKD1_k127_6050766_7 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
HKD1_k127_6050766_8 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000008786 273.0
HKD1_k127_6050766_9 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 268.0
HKD1_k127_6058769_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 1.6e-322 1011.0
HKD1_k127_6058769_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.507e-310 966.0
HKD1_k127_6058769_10 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 309.0
HKD1_k127_6058769_11 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 331.0
HKD1_k127_6058769_12 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 321.0
HKD1_k127_6058769_13 dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007194 263.0
HKD1_k127_6058769_14 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000009717 238.0
HKD1_k127_6058769_15 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000000001045 221.0
HKD1_k127_6058769_16 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000861 211.0
HKD1_k127_6058769_17 DoxX K15977 - - 0.00000000000000000000000000000000000000103 156.0
HKD1_k127_6058769_18 electron transfer activity K03737,K05337 - 1.2.7.1 0.00001132 59.0
HKD1_k127_6058769_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 2.313e-263 823.0
HKD1_k127_6058769_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.39e-233 731.0
HKD1_k127_6058769_4 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 2.267e-221 703.0
HKD1_k127_6058769_5 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 545.0
HKD1_k127_6058769_6 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 505.0
HKD1_k127_6058769_7 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 482.0
HKD1_k127_6058769_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 481.0
HKD1_k127_6058769_9 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 347.0
HKD1_k127_6087091_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 3.189e-299 937.0
HKD1_k127_6087091_1 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 534.0
HKD1_k127_6087091_10 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000002981 211.0
HKD1_k127_6087091_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000000000000000000001204 178.0
HKD1_k127_6087091_12 - - - - 0.0000000000000000000000000000004846 128.0
HKD1_k127_6087091_13 Transcriptional regulator K04033 - - 0.00000000000000000000000002221 121.0
HKD1_k127_6087091_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 376.0
HKD1_k127_6087091_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 352.0
HKD1_k127_6087091_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 340.0
HKD1_k127_6087091_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 315.0
HKD1_k127_6087091_6 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 308.0
HKD1_k127_6087091_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 295.0
HKD1_k127_6087091_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001314 244.0
HKD1_k127_6087091_9 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000001094 233.0
HKD1_k127_6087841_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.358e-281 883.0
HKD1_k127_6087841_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 6.865e-225 706.0
HKD1_k127_6087841_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 321.0
HKD1_k127_6087841_11 proteins homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001272 288.0
HKD1_k127_6087841_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001887 275.0
HKD1_k127_6087841_13 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001404 263.0
HKD1_k127_6087841_14 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000167 232.0
HKD1_k127_6087841_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000003766 246.0
HKD1_k127_6087841_16 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000547 214.0
HKD1_k127_6087841_17 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000003171 207.0
HKD1_k127_6087841_18 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000001444 200.0
HKD1_k127_6087841_19 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000005379 200.0
HKD1_k127_6087841_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 466.0
HKD1_k127_6087841_20 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000007006 176.0
HKD1_k127_6087841_21 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000003335 148.0
HKD1_k127_6087841_22 n-acetyltransferase - - - 0.0000000000000000000000000000000000001869 159.0
HKD1_k127_6087841_23 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000008919 135.0
HKD1_k127_6087841_24 Domain of unknown function (DUF4397) - - - 0.000000000000000005502 95.0
HKD1_k127_6087841_25 - - - - 0.0000000000000004438 86.0
HKD1_k127_6087841_26 Domain of unknown function (DUF4936) - - - 0.00000000007407 74.0
HKD1_k127_6087841_3 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 433.0
HKD1_k127_6087841_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 404.0
HKD1_k127_6087841_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 389.0
HKD1_k127_6087841_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 376.0
HKD1_k127_6087841_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 362.0
HKD1_k127_6087841_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 339.0
HKD1_k127_6087841_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 334.0
HKD1_k127_6102530_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000004613 229.0
HKD1_k127_6102530_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000001292 170.0
HKD1_k127_6102530_2 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000001905 145.0
HKD1_k127_6102530_3 MacB-like periplasmic core domain K02004 - - 0.0007745 42.0
HKD1_k127_6158117_0 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000481 232.0
HKD1_k127_6158117_1 Catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
HKD1_k127_6158117_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000005841 56.0
HKD1_k127_6169179_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 507.0
HKD1_k127_6169179_1 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 317.0
HKD1_k127_6169179_2 RES - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 312.0
HKD1_k127_6169179_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000001185 262.0
HKD1_k127_6169179_4 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000007666 115.0
HKD1_k127_6169179_5 Astacin (Peptidase family M12A) - - - 0.000000000000000000001431 110.0
HKD1_k127_6183598_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 458.0
HKD1_k127_6183598_1 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004999 283.0
HKD1_k127_6183598_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002818 160.0
HKD1_k127_6183598_3 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000006443 134.0
HKD1_k127_6183598_4 Transcriptional regulator - - - 0.000000000001483 71.0
HKD1_k127_6183598_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000001919 57.0
HKD1_k127_6183598_6 Phage related protein - - - 0.0005016 42.0
HKD1_k127_6205536_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 441.0
HKD1_k127_6205536_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 400.0
HKD1_k127_6205536_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 330.0
HKD1_k127_6230317_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001066 260.0
HKD1_k127_6230317_1 abc transporter, permease K02050 - - 0.0000000000000000000000000000000000000000000000754 175.0
HKD1_k127_6230317_2 Thioesterase - - - 0.000000000000000000000000000000000000000001022 161.0
HKD1_k127_6237953_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.344e-199 653.0
HKD1_k127_6237953_1 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 496.0
HKD1_k127_6237953_10 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000008575 179.0
HKD1_k127_6237953_11 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000001586 117.0
HKD1_k127_6237953_12 Protein of unknown function (DUF3617) - - - 0.000000000000000000000001217 116.0
HKD1_k127_6237953_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000003778 65.0
HKD1_k127_6237953_2 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 428.0
HKD1_k127_6237953_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 407.0
HKD1_k127_6237953_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 365.0
HKD1_k127_6237953_5 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 371.0
HKD1_k127_6237953_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 334.0
HKD1_k127_6237953_7 Tetratricopeptide repeat K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007445 254.0
HKD1_k127_6237953_8 Belongs to the peptidase S11 family K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000001248 229.0
HKD1_k127_6237953_9 protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000000000001472 184.0
HKD1_k127_6267520_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000006752 185.0
HKD1_k127_6267520_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000007241 161.0
HKD1_k127_6267520_2 - - - - 0.0000000000000000000000000004702 127.0
HKD1_k127_6269412_0 Patatin-like phospholipase K07001 - - 3.419e-250 793.0
HKD1_k127_6269412_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.663e-244 762.0
HKD1_k127_6269412_10 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002548 245.0
HKD1_k127_6269412_11 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000001034 246.0
HKD1_k127_6269412_12 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000004271 182.0
HKD1_k127_6269412_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000002395 158.0
HKD1_k127_6269412_14 Thrombospondin type 3 repeat - - - 0.0000000000001293 75.0
HKD1_k127_6269412_15 Belongs to the peptidase S8 family K14645 - - 0.00000743 60.0
HKD1_k127_6269412_2 Cysteine-rich domain - - - 7.791e-209 659.0
HKD1_k127_6269412_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 528.0
HKD1_k127_6269412_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 515.0
HKD1_k127_6269412_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 471.0
HKD1_k127_6269412_6 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 441.0
HKD1_k127_6269412_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 377.0
HKD1_k127_6269412_8 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 383.0
HKD1_k127_6269412_9 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001734 256.0
HKD1_k127_6316484_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 520.0
HKD1_k127_6316484_1 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
HKD1_k127_6316484_2 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000173 270.0
HKD1_k127_6316484_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000001556 186.0
HKD1_k127_6316484_4 COG0302 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000002654 160.0
HKD1_k127_6316484_5 iron ion homeostasis - - - 0.000000000000000000000000000000000000001527 158.0
HKD1_k127_6316484_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000008974 134.0
HKD1_k127_6326717_0 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000001578 211.0
HKD1_k127_6326717_1 domain, Protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000001528 169.0
HKD1_k127_6326717_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000001177 166.0
HKD1_k127_6326717_3 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000001035 101.0
HKD1_k127_6330882_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1353.0
HKD1_k127_6330882_1 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 502.0
HKD1_k127_6330882_2 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 439.0
HKD1_k127_6330882_3 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 437.0
HKD1_k127_6330882_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 293.0
HKD1_k127_6352269_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 609.0
HKD1_k127_6352269_1 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 436.0
HKD1_k127_635327_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 491.0
HKD1_k127_635327_1 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 431.0
HKD1_k127_635327_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 401.0
HKD1_k127_635327_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 305.0
HKD1_k127_635327_4 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 291.0
HKD1_k127_635327_5 sodium ABC transporter, permease K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000118 233.0
HKD1_k127_635327_6 Iron permease FTR1 family K07243 - - 0.000000000000000000001312 96.0
HKD1_k127_635327_7 Protein of unknown function (DUF2970) - - - 0.000000000317 64.0
HKD1_k127_6359201_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1178.0
HKD1_k127_6359201_1 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 1.898e-286 885.0
HKD1_k127_6359201_10 peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000002669 211.0
HKD1_k127_6359201_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000005527 196.0
HKD1_k127_6359201_12 Nitrate reductase, delta subunit K00373 - - 0.00000000000000000000000000000000000000000000009405 190.0
HKD1_k127_6359201_13 Protein of unknown function (DUF1282) - - - 0.000000000000000000000000000000000000001723 155.0
HKD1_k127_6359201_14 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000001203 124.0
HKD1_k127_6359201_15 Protein of unknown function (DUF1059) - - - 0.000000000000000001344 89.0
HKD1_k127_6359201_16 - - - - 0.000000000000002166 89.0
HKD1_k127_6359201_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 548.0
HKD1_k127_6359201_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 531.0
HKD1_k127_6359201_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 512.0
HKD1_k127_6359201_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 349.0
HKD1_k127_6359201_6 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 339.0
HKD1_k127_6359201_7 Nitrate reductase K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 316.0
HKD1_k127_6359201_8 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 282.0
HKD1_k127_6359201_9 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 288.0
HKD1_k127_6366940_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 6.174e-253 792.0
HKD1_k127_6366940_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.718e-241 762.0
HKD1_k127_6366940_10 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 393.0
HKD1_k127_6366940_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 330.0
HKD1_k127_6366940_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 298.0
HKD1_k127_6366940_13 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000008198 250.0
HKD1_k127_6366940_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001125 258.0
HKD1_k127_6366940_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004423 248.0
HKD1_k127_6366940_16 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000004068 193.0
HKD1_k127_6366940_18 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000001026 151.0
HKD1_k127_6366940_19 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000001203 131.0
HKD1_k127_6366940_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 9.467e-230 720.0
HKD1_k127_6366940_20 of cations and cationic drugs K03297 - - 0.00000000000000000000000000000008357 127.0
HKD1_k127_6366940_21 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.0000000000000000000000000002806 117.0
HKD1_k127_6366940_22 Phage tail sheath protein K06907 - - 0.000000000000000000000411 99.0
HKD1_k127_6366940_23 CoA carboxylase activity K01615,K01965,K02160,K17490 - 2.1.3.1,4.1.1.70,6.4.1.3 0.00000000000000000009241 104.0
HKD1_k127_6366940_24 Transcriptional regulator - - - 0.00000000000000000226 94.0
HKD1_k127_6366940_26 - - - - 0.000000007179 66.0
HKD1_k127_6366940_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 623.0
HKD1_k127_6366940_4 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 592.0
HKD1_k127_6366940_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 531.0
HKD1_k127_6366940_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 544.0
HKD1_k127_6366940_7 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 486.0
HKD1_k127_6366940_8 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 428.0
HKD1_k127_6366940_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 461.0
HKD1_k127_6367315_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 6.034e-231 728.0
HKD1_k127_6367315_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 2.589e-226 709.0
HKD1_k127_6367315_10 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000001341 112.0
HKD1_k127_6367315_11 Protein of unknown function (DUF2783) - - - 0.0000000000000000004607 91.0
HKD1_k127_6367315_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 541.0
HKD1_k127_6367315_3 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 529.0
HKD1_k127_6367315_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 468.0
HKD1_k127_6367315_5 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 366.0
HKD1_k127_6367315_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 355.0
HKD1_k127_6367315_7 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 300.0
HKD1_k127_6367315_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000107 269.0
HKD1_k127_6367315_9 Nitroreductase family - - - 0.000000000000000000000000000000000000000000005102 171.0
HKD1_k127_6394660_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 3.31e-305 951.0
HKD1_k127_6394660_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.69e-218 717.0
HKD1_k127_6394660_10 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 386.0
HKD1_k127_6394660_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 311.0
HKD1_k127_6394660_12 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003924 280.0
HKD1_k127_6394660_13 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001112 259.0
HKD1_k127_6394660_14 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000001694 254.0
HKD1_k127_6394660_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000005498 230.0
HKD1_k127_6394660_17 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000003013 183.0
HKD1_k127_6394660_18 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000002245 176.0
HKD1_k127_6394660_19 Chalcone isomerase-like - - - 0.00000000000000000000000000000000002056 142.0
HKD1_k127_6394660_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 571.0
HKD1_k127_6394660_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000157 124.0
HKD1_k127_6394660_21 Frataxin-like domain - - - 0.0000000000000000000000001692 109.0
HKD1_k127_6394660_22 - - - - 0.00000000000000007829 94.0
HKD1_k127_6394660_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 538.0
HKD1_k127_6394660_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 521.0
HKD1_k127_6394660_5 PhoH-like phosphate starvation-inducible protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 458.0
HKD1_k127_6394660_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 448.0
HKD1_k127_6394660_7 Transcriptional regulator K03603,K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 426.0
HKD1_k127_6394660_8 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 425.0
HKD1_k127_6394660_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 424.0
HKD1_k127_6398890_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 549.0
HKD1_k127_6398890_1 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 318.0
HKD1_k127_6452929_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 510.0
HKD1_k127_6452929_2 Belongs to the peptidase S8 family - - - 0.00003042 50.0
HKD1_k127_6495851_0 FtsX-like permease family K02004 - - 1.3e-244 791.0
HKD1_k127_6495851_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 403.0
HKD1_k127_6495851_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 350.0
HKD1_k127_6495851_3 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001396 271.0
HKD1_k127_6495851_4 Lipocalin-like domain - - - 0.00000000000000000000000000000002281 147.0
HKD1_k127_6495851_5 acid phosphatase activity K01077 - 3.1.3.1 0.000000000000000000006408 94.0
HKD1_k127_6495851_6 cyclic nucleotide binding K10914 - - 0.0000000000000000001638 98.0
HKD1_k127_6527040_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 351.0
HKD1_k127_6527040_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 342.0
HKD1_k127_6531394_0 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 452.0
HKD1_k127_6531394_1 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000981 191.0
HKD1_k127_6531394_2 fimbrial assembly K02461 - - 0.0000000000000000000000000000000001735 151.0
HKD1_k127_6531394_3 General secretion pathway protein K02459 - - 0.000000000000003792 87.0
HKD1_k127_6531394_4 - - - - 0.00000000000004896 78.0
HKD1_k127_6531394_5 Prokaryotic N-terminal methylation motif - - - 0.00000000002054 70.0
HKD1_k127_6531394_6 General secretion pathway protein M K02462 - - 0.000000003958 70.0
HKD1_k127_6531394_7 General secretion pathway protein H K02457 - - 0.0000001229 53.0
HKD1_k127_6534102_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2e-323 1003.0
HKD1_k127_6534102_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.994e-248 786.0
HKD1_k127_6534102_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 331.0
HKD1_k127_6534102_11 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 342.0
HKD1_k127_6534102_12 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 321.0
HKD1_k127_6534102_13 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 312.0
HKD1_k127_6534102_14 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 299.0
HKD1_k127_6534102_15 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 296.0
HKD1_k127_6534102_16 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 288.0
HKD1_k127_6534102_17 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003201 292.0
HKD1_k127_6534102_18 amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000009296 238.0
HKD1_k127_6534102_19 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000008429 192.0
HKD1_k127_6534102_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 2.836e-241 749.0
HKD1_k127_6534102_20 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000006242 145.0
HKD1_k127_6534102_23 amino acid-binding ACT domain protein K04767 - - 0.000000000000000000000000002618 116.0
HKD1_k127_6534102_24 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000008521 113.0
HKD1_k127_6534102_25 FeoA - - - 0.000001312 62.0
HKD1_k127_6534102_3 Sulfatase - - - 1.288e-213 688.0
HKD1_k127_6534102_4 Metallopeptidase family M24 - - - 1.215e-208 659.0
HKD1_k127_6534102_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 421.0
HKD1_k127_6534102_6 Extracellular solute-binding protein family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 409.0
HKD1_k127_6534102_7 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 376.0
HKD1_k127_6534102_8 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
HKD1_k127_6534102_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 361.0
HKD1_k127_6559232_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.54e-197 621.0
HKD1_k127_6559232_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000004026 188.0
HKD1_k127_67171_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 4.387e-271 842.0
HKD1_k127_67171_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 504.0
HKD1_k127_67171_10 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000002664 231.0
HKD1_k127_67171_11 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000002073 224.0
HKD1_k127_67171_12 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000006756 209.0
HKD1_k127_67171_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 419.0
HKD1_k127_67171_3 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 396.0
HKD1_k127_67171_4 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 363.0
HKD1_k127_67171_5 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 373.0
HKD1_k127_67171_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 370.0
HKD1_k127_67171_7 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 333.0
HKD1_k127_67171_8 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 305.0
HKD1_k127_67171_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 306.0
HKD1_k127_6782522_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000001422 246.0
HKD1_k127_6923523_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 420.0
HKD1_k127_6923523_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
HKD1_k127_6923523_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 338.0
HKD1_k127_6923523_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000001018 235.0
HKD1_k127_6923523_4 Ribonuclease III family K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000002166 178.0
HKD1_k127_6977905_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 364.0
HKD1_k127_6977905_1 PFAM NapC NirT cytochrome c K02569 - - 0.0000000000000000000004083 96.0
HKD1_k127_7047482_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1515.0
HKD1_k127_7047482_1 OPT oligopeptide transporter protein - - - 2.227e-248 797.0
HKD1_k127_7047482_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000008682 192.0
HKD1_k127_7047482_11 4Fe-4S dicluster domain K00196,K05796 - - 0.0000000000000000000000000000000000000000000000000116 195.0
HKD1_k127_7047482_12 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000001184 171.0
HKD1_k127_7047482_13 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000001141 169.0
HKD1_k127_7047482_14 - - - - 0.00000000000000000000000000000000002815 152.0
HKD1_k127_7047482_15 Copper resistance protein D - - - 0.00000000000000000000000000000004039 130.0
HKD1_k127_7047482_16 Integral membrane sensor signal transduction histidine kinase K07646 - 2.7.13.3 0.00000000000000000000001997 108.0
HKD1_k127_7047482_17 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000001272 79.0
HKD1_k127_7047482_18 Subtilase family - - - 0.0000000000000004413 93.0
HKD1_k127_7047482_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 623.0
HKD1_k127_7047482_20 PFAM thiamineS protein - - - 0.000001322 53.0
HKD1_k127_7047482_3 PFAM polysaccharide deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 481.0
HKD1_k127_7047482_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 499.0
HKD1_k127_7047482_5 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 462.0
HKD1_k127_7047482_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 311.0
HKD1_k127_7047482_7 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001387 259.0
HKD1_k127_7047482_8 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001312 246.0
HKD1_k127_7047482_9 peptidase inhibitor activity K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000001592 239.0
HKD1_k127_7047809_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - - 2.517e-226 731.0
HKD1_k127_7047809_1 PFAM acyl-CoA dehydrogenase domain protein K00249,K07545 - 1.3.8.3,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 547.0
HKD1_k127_7047809_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 331.0
HKD1_k127_7047809_3 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000102 283.0
HKD1_k127_7047809_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000004938 237.0
HKD1_k127_7047809_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006103 231.0
HKD1_k127_7048377_0 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000000000000000000000000000002311 220.0
HKD1_k127_7048377_1 pilus assembly protein PilE K02655 - - 0.0000000000000000000001143 104.0
HKD1_k127_7048377_2 type IV pilus assembly protein PilV K02671 - - 0.0000000000000000000007712 109.0
HKD1_k127_7048377_3 type 4 fimbrial pilin related transmembrane protein K08084 - - 0.000000000000006692 81.0
HKD1_k127_7059230_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 488.0
HKD1_k127_7059230_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000001365 190.0
HKD1_k127_7059230_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00001363 58.0
HKD1_k127_7064315_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 1.974e-264 826.0
HKD1_k127_7064315_1 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000001233 226.0
HKD1_k127_7064315_2 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000001874 112.0
HKD1_k127_7064315_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000001889 104.0
HKD1_k127_7076643_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1168.0
HKD1_k127_7076643_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.23e-295 939.0
HKD1_k127_7076643_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 467.0
HKD1_k127_7076643_11 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 459.0
HKD1_k127_7076643_12 MCM2/3/5 family K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 451.0
HKD1_k127_7076643_13 Luciferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 421.0
HKD1_k127_7076643_14 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 329.0
HKD1_k127_7076643_15 Helix-turn-helix type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 325.0
HKD1_k127_7076643_16 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000004351 275.0
HKD1_k127_7076643_17 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
HKD1_k127_7076643_18 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000005409 231.0
HKD1_k127_7076643_19 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000003586 198.0
HKD1_k127_7076643_2 Bacterial extracellular solute-binding proteins, family 5 Middle K12368 - - 2.233e-265 819.0
HKD1_k127_7076643_20 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000009301 189.0
HKD1_k127_7076643_21 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000002553 185.0
HKD1_k127_7076643_22 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000007458 184.0
HKD1_k127_7076643_23 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000001131 190.0
HKD1_k127_7076643_24 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000004117 183.0
HKD1_k127_7076643_25 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000891 163.0
HKD1_k127_7076643_26 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000000002022 130.0
HKD1_k127_7076643_27 - - - - 0.0000000000000004584 91.0
HKD1_k127_7076643_28 - - - - 0.0000000003991 69.0
HKD1_k127_7076643_29 response regulator - - - 0.00000003199 62.0
HKD1_k127_7076643_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.346e-255 799.0
HKD1_k127_7076643_30 - - - - 0.0000003598 62.0
HKD1_k127_7076643_31 Acetyltransferase (GNAT) domain - - - 0.00001055 57.0
HKD1_k127_7076643_4 PFAM electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 9.759e-238 749.0
HKD1_k127_7076643_5 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 6.222e-232 725.0
HKD1_k127_7076643_6 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 9.143e-194 613.0
HKD1_k127_7076643_7 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 603.0
HKD1_k127_7076643_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 515.0
HKD1_k127_7076643_9 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 492.0
HKD1_k127_7081362_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.024e-219 692.0
HKD1_k127_7081362_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 438.0
HKD1_k127_7081362_2 methyltransferase K03437 - - 0.000000000000000000000000000000000000000000000000000000003121 209.0
HKD1_k127_7081362_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000000004232 130.0
HKD1_k127_7081362_4 Stress responsive A/B Barrel Domain - - - 0.00000000000000000001215 105.0
HKD1_k127_7083780_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 576.0
HKD1_k127_7083780_1 Major Facilitator Superfamily K08159,K19577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 329.0
HKD1_k127_7100989_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 3.076e-233 743.0
HKD1_k127_7100989_1 HD domain K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 376.0
HKD1_k127_7100989_2 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001166 191.0
HKD1_k127_7100989_3 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000001921 171.0
HKD1_k127_7100989_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000007804 171.0
HKD1_k127_7100989_5 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000121 158.0
HKD1_k127_7100989_6 PFAM Na H antiporter subunit K05564 - - 0.000000000000000000001404 104.0
HKD1_k127_7100989_7 Multiple resistance and pH regulation protein F K05563 - - 0.000000000000000000007085 99.0
HKD1_k127_7103394_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.074e-302 938.0
HKD1_k127_7103394_1 Polysaccharide biosynthesis protein - - - 1.16e-223 710.0
HKD1_k127_7103394_10 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 392.0
HKD1_k127_7103394_11 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 391.0
HKD1_k127_7103394_12 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 396.0
HKD1_k127_7103394_13 glycosyl transferase group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 348.0
HKD1_k127_7103394_14 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 321.0
HKD1_k127_7103394_15 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 318.0
HKD1_k127_7103394_16 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 310.0
HKD1_k127_7103394_17 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 318.0
HKD1_k127_7103394_18 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000007572 241.0
HKD1_k127_7103394_19 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000000000000001064 227.0
HKD1_k127_7103394_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.423e-208 673.0
HKD1_k127_7103394_20 PFAM regulatory protein TetR K05501 - - 0.000000000000000000000000000000000000000000000000000000000000005071 236.0
HKD1_k127_7103394_21 Protein of unknown function (DUF4254) - - - 0.0000000000000000000000000000000000000000000000000000000000001375 234.0
HKD1_k127_7103394_22 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000005153 201.0
HKD1_k127_7103394_23 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000006263 209.0
HKD1_k127_7103394_24 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000001516 164.0
HKD1_k127_7103394_25 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000205 171.0
HKD1_k127_7103394_26 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000299 142.0
HKD1_k127_7103394_27 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000004569 138.0
HKD1_k127_7103394_28 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000001611 137.0
HKD1_k127_7103394_29 O-Antigen ligase - - - 0.00000000000000000000000000003925 132.0
HKD1_k127_7103394_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 585.0
HKD1_k127_7103394_30 Integral membrane protein (DUF2244) - - - 0.00000001143 63.0
HKD1_k127_7103394_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 548.0
HKD1_k127_7103394_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 494.0
HKD1_k127_7103394_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 490.0
HKD1_k127_7103394_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 430.0
HKD1_k127_7103394_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 419.0
HKD1_k127_7103394_9 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 391.0
HKD1_k127_7103455_0 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 1.234e-241 757.0
HKD1_k127_7103455_1 PFAM Acyl-CoA dehydrogenase K00252 - 1.3.8.6 3.558e-210 659.0
HKD1_k127_7103455_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 505.0
HKD1_k127_7103455_3 Maleylacetoacetate isomerase K01801 - 5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002004 279.0
HKD1_k127_7103455_4 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000002204 200.0
HKD1_k127_7103455_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000002176 73.0
HKD1_k127_7141561_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1285.0
HKD1_k127_7141561_1 Met-10+ like-protein - - - 0.000703 42.0
HKD1_k127_7147245_0 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 511.0
HKD1_k127_7147245_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 306.0
HKD1_k127_7147245_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000005437 231.0
HKD1_k127_7147245_3 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000001397 228.0
HKD1_k127_7147245_4 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000003173 162.0
HKD1_k127_7147245_5 Domain of unknown function DUF123 - - - 0.000000000000000000000000000000007978 130.0
HKD1_k127_7147245_6 NnrU protein - - - 0.000000000000000000000000000002774 130.0
HKD1_k127_7147245_7 Protein of unknown function (DUF1499) - - - 0.0000001996 53.0
HKD1_k127_7148504_0 Solute carrier family 35 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000181 283.0
HKD1_k127_7148504_1 e3 binding domain K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000001785 250.0
HKD1_k127_7148504_2 Glucosyl transferase GtrII - - - 0.0000000000000000000000000000000000000000000000000000001724 209.0
HKD1_k127_7148504_3 Protein of unknown function (DUF465) - - - 0.000000002026 69.0
HKD1_k127_7178779_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 2.84e-268 834.0
HKD1_k127_7178779_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 373.0
HKD1_k127_7178779_2 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.00000000000000003471 82.0
HKD1_k127_7221692_0 TRAP transporter 4TM 12TM fusion - - - 8.843e-293 915.0
HKD1_k127_7221692_1 oxidase subunit I K00425 - 1.10.3.14 2.315e-212 671.0
HKD1_k127_7221692_10 Cytochrome c - - - 0.0000000000000000000000004554 109.0
HKD1_k127_7221692_11 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000002131 61.0
HKD1_k127_7221692_12 regulator K07684 - - 0.00000002209 60.0
HKD1_k127_7221692_2 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 465.0
HKD1_k127_7221692_3 TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 460.0
HKD1_k127_7221692_4 oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 458.0
HKD1_k127_7221692_5 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008558 274.0
HKD1_k127_7221692_6 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006867 263.0
HKD1_k127_7221692_7 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000008561 244.0
HKD1_k127_7221692_8 Domain of unknown function (DUF1850) - - - 0.00000000000000000000000000002123 121.0
HKD1_k127_7221692_9 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000005841 121.0
HKD1_k127_7238194_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 610.0
HKD1_k127_7238194_1 Dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000486 174.0
HKD1_k127_7284511_0 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 456.0
HKD1_k127_7284511_1 ThiS family K03636 - - 0.000000000000001483 89.0
HKD1_k127_7284511_2 ATP synthase I chain K02116 - - 0.000000002461 68.0
HKD1_k127_7327855_0 PFAM NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1142.0
HKD1_k127_7327855_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 419.0
HKD1_k127_7327855_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 303.0
HKD1_k127_7327855_3 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000000000002367 201.0
HKD1_k127_7327855_4 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000001656 126.0
HKD1_k127_7327855_5 Type II transport protein GspH K08084 - - 0.00000000000000000000000002919 120.0
HKD1_k127_7327855_6 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000002334 112.0
HKD1_k127_7327855_7 type IV pilus modification protein PilV K02671 - - 0.0000000000000000001985 102.0
HKD1_k127_7327855_8 Type II transport protein GspH K08084 - - 0.00000000000001466 81.0
HKD1_k127_7413264_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0 1075.0
HKD1_k127_7413264_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 6.065e-296 926.0
HKD1_k127_7413264_10 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 302.0
HKD1_k127_7413264_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001921 282.0
HKD1_k127_7413264_12 response regulator K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000001293 225.0
HKD1_k127_7413264_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000001651 194.0
HKD1_k127_7413264_14 -Thioesterase K01075 - 3.1.2.23 0.00000000000000000000000000000000000000000001741 168.0
HKD1_k127_7413264_15 diguanylate cyclase - - - 0.000000000000000000000000000000000000000007235 166.0
HKD1_k127_7413264_16 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000007616 149.0
HKD1_k127_7413264_17 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000832 58.0
HKD1_k127_7413264_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.312e-277 900.0
HKD1_k127_7413264_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.968e-215 676.0
HKD1_k127_7413264_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 520.0
HKD1_k127_7413264_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 442.0
HKD1_k127_7413264_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 393.0
HKD1_k127_7413264_7 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 383.0
HKD1_k127_7413264_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 302.0
HKD1_k127_7413264_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 299.0
HKD1_k127_7424654_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 4.049e-290 902.0
HKD1_k127_7424654_1 D-amino acid K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 453.0
HKD1_k127_7439832_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 524.0
HKD1_k127_7439832_1 Orn/Lys/Arg decarboxylase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001095 192.0
HKD1_k127_7453415_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 574.0
HKD1_k127_7453415_1 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 567.0
HKD1_k127_7453415_2 N-terminal TM domain of oligopeptide transport permease C K02034,K12370 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 468.0
HKD1_k127_7453415_3 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001503 259.0
HKD1_k127_7453415_4 - - - - 0.000000001393 69.0
HKD1_k127_7457173_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 9.23e-297 955.0
HKD1_k127_7457173_1 transport systems, ATPase components K02056 - 3.6.3.17 4.411e-210 671.0
HKD1_k127_7457173_10 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000003456 220.0
HKD1_k127_7457173_11 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000001142 186.0
HKD1_k127_7457173_12 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000001558 90.0
HKD1_k127_7457173_13 Glycine zipper 2TM domain - - - 0.00000001443 63.0
HKD1_k127_7457173_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 564.0
HKD1_k127_7457173_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 511.0
HKD1_k127_7457173_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 367.0
HKD1_k127_7457173_5 PFAM ABC transporter related K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 307.0
HKD1_k127_7457173_6 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000142 279.0
HKD1_k127_7457173_7 Mammalian cell entry related domain protein K02067,K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 266.0
HKD1_k127_7457173_8 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003638 267.0
HKD1_k127_7457173_9 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000004706 226.0
HKD1_k127_7486267_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1130.0
HKD1_k127_7486267_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 370.0
HKD1_k127_7486267_2 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 325.0
HKD1_k127_7486267_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 324.0
HKD1_k127_7486267_4 permeases of the drug metabolite transporter (Dmt) superfamily - - - 0.0000000000000000000000000000000000000000000000000000003072 213.0
HKD1_k127_7486267_5 - - - - 0.0000005268 55.0
HKD1_k127_7518023_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 470.0
HKD1_k127_7518023_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002464 273.0
HKD1_k127_7518023_2 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002524 251.0
HKD1_k127_7518023_3 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000001433 130.0
HKD1_k127_7545056_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 472.0
HKD1_k127_7545056_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000002162 206.0
HKD1_k127_7545844_0 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 513.0
HKD1_k127_7545844_1 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 477.0
HKD1_k127_7545844_2 PFAM extracellular solute-binding protein family 5 K12368 - - 0.0000000000000000000000000000000000000000000000000000000000006117 212.0
HKD1_k127_7545844_3 N-terminal TM domain of oligopeptide transport permease C K02034,K12370 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000002587 87.0
HKD1_k127_7599673_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.049e-251 781.0
HKD1_k127_7599673_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 5.318e-240 758.0
HKD1_k127_7599673_2 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 507.0
HKD1_k127_7599673_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 472.0
HKD1_k127_7599673_4 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
HKD1_k127_7599673_5 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 432.0
HKD1_k127_7599673_6 Phosphopantetheine attachment site - - - 0.00000000000000000000001696 104.0
HKD1_k127_7623641_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 466.0
HKD1_k127_7623641_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000007325 149.0
HKD1_k127_7643602_0 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 329.0
HKD1_k127_7643602_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 323.0
HKD1_k127_7643602_2 lipoprotein releasing system, transmembrane protein, LolC E family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002336 273.0
HKD1_k127_7643602_3 DoxX K15977 - - 0.00000000000000000000000000000000000000000000001119 174.0
HKD1_k127_7698627_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 550.0
HKD1_k127_7698627_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000388 281.0
HKD1_k127_7698627_2 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000567 272.0
HKD1_k127_7698627_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000002656 179.0
HKD1_k127_7698627_4 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000008727 183.0
HKD1_k127_7698627_5 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000008468 176.0
HKD1_k127_7698627_6 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000005611 158.0
HKD1_k127_7698627_7 TonB C terminal K03646 - - 0.0000000000000000000000000000000000000138 159.0
HKD1_k127_7698627_8 Tol-pal system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000001677 137.0
HKD1_k127_7763401_0 Belongs to the IlvD Edd family - - - 5.142e-276 859.0
HKD1_k127_7763401_1 Sulfatase K01130 - 3.1.6.1 3.353e-269 831.0
HKD1_k127_7763401_10 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 404.0
HKD1_k127_7763401_11 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 397.0
HKD1_k127_7763401_12 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 365.0
HKD1_k127_7763401_13 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 338.0
HKD1_k127_7763401_14 Belongs to the HpcH HpaI aldolase family K01630 - 4.1.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 321.0
HKD1_k127_7763401_15 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 320.0
HKD1_k127_7763401_16 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 329.0
HKD1_k127_7763401_17 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 306.0
HKD1_k127_7763401_18 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001425 289.0
HKD1_k127_7763401_19 Enoyl-(Acyl carrier protein) reductase K22185 - 1.1.1.175 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005688 276.0
HKD1_k127_7763401_2 (ABC) transporter K01995 - - 6.792e-211 685.0
HKD1_k127_7763401_20 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002088 263.0
HKD1_k127_7763401_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001244 239.0
HKD1_k127_7763401_22 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000001539 241.0
HKD1_k127_7763401_23 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000003942 223.0
HKD1_k127_7763401_24 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000006196 224.0
HKD1_k127_7763401_25 YGGT family - - - 0.00000000000000000000000000000000000009268 148.0
HKD1_k127_7763401_26 DUF167 K09131 - - 0.00000000000000000000000002813 119.0
HKD1_k127_7763401_27 - - - - 0.00000000000000000000000007406 111.0
HKD1_k127_7763401_28 - - - - 0.000000000000000000000002342 106.0
HKD1_k127_7763401_29 COG1226 Kef-type K transport systems - - - 0.0000001625 62.0
HKD1_k127_7763401_3 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 9.813e-207 671.0
HKD1_k127_7763401_4 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 610.0
HKD1_k127_7763401_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 558.0
HKD1_k127_7763401_6 ABC-type sugar transport system periplasmic component K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 537.0
HKD1_k127_7763401_7 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 488.0
HKD1_k127_7763401_8 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 441.0
HKD1_k127_7763401_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 409.0
HKD1_k127_86935_0 Rhodanese Homology Domain K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 371.0
HKD1_k127_86935_1 phenazine biosynthesis protein PhzF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
HKD1_k127_86935_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 297.0
HKD1_k127_86935_3 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000001517 228.0
HKD1_k127_86935_4 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.000000000000000000000000000000000000000000000000006485 190.0
HKD1_k127_86935_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000001125 137.0
HKD1_k127_87419_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 415.0
HKD1_k127_87419_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 406.0
HKD1_k127_87419_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 392.0
HKD1_k127_87419_3 Aldehyde dehydrogenase family K04072,K13922 - 1.1.1.1,1.2.1.10,1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 354.0
HKD1_k127_87419_4 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 350.0
HKD1_k127_87419_5 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 293.0
HKD1_k127_87419_6 helix_turn_helix isocitrate lyase regulation K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000002903 243.0
HKD1_k127_87711_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 358.0
HKD1_k127_87711_1 OsmC-like protein - - - 0.000000000000000000000000001787 117.0
HKD1_k127_89909_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.32e-205 649.0
HKD1_k127_89909_1 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000001035 213.0