Overview

ID MAG01758
Name HKD1_bin.78
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus DAHUXD01
Species
Assembly information
Completeness (%) 82.9
Contamination (%) 0.58
GC content (%) 71.0
N50 (bp) 18,809
Genome size (bp) 3,907,499

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3231

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1011545_0 Cysteine-rich domain - - - 1.329e-207 674.0
HKD1_k127_1011545_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 542.0
HKD1_k127_1011545_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 330.0
HKD1_k127_1011545_11 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 321.0
HKD1_k127_1011545_12 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 321.0
HKD1_k127_1011545_13 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 329.0
HKD1_k127_1011545_14 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001948 281.0
HKD1_k127_1011545_15 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
HKD1_k127_1011545_16 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000824 299.0
HKD1_k127_1011545_17 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000004934 273.0
HKD1_k127_1011545_18 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000001835 265.0
HKD1_k127_1011545_19 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000002277 241.0
HKD1_k127_1011545_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 522.0
HKD1_k127_1011545_20 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000001508 235.0
HKD1_k127_1011545_21 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000001015 251.0
HKD1_k127_1011545_22 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000034 229.0
HKD1_k127_1011545_23 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000002435 217.0
HKD1_k127_1011545_24 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000002171 201.0
HKD1_k127_1011545_25 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000952 203.0
HKD1_k127_1011545_26 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000004208 203.0
HKD1_k127_1011545_27 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000002436 175.0
HKD1_k127_1011545_28 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000002116 142.0
HKD1_k127_1011545_29 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000007102 127.0
HKD1_k127_1011545_3 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 522.0
HKD1_k127_1011545_31 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000132 112.0
HKD1_k127_1011545_32 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000002942 124.0
HKD1_k127_1011545_33 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000001664 104.0
HKD1_k127_1011545_34 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000009851 102.0
HKD1_k127_1011545_35 Ribosomal L32p protein family K02911 - - 0.000000000000000000003311 95.0
HKD1_k127_1011545_36 Belongs to the UPF0102 family K07460 - - 0.000000000000000000003413 98.0
HKD1_k127_1011545_37 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000002342 106.0
HKD1_k127_1011545_38 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000005511 60.0
HKD1_k127_1011545_39 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000007452 63.0
HKD1_k127_1011545_4 recA bacterial DNA recombination protein K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 486.0
HKD1_k127_1011545_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 496.0
HKD1_k127_1011545_6 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 435.0
HKD1_k127_1011545_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 399.0
HKD1_k127_1011545_8 TIGRFAM argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 372.0
HKD1_k127_1011545_9 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 356.0
HKD1_k127_1013827_0 Prokaryotic cytochrome b561 - - - 0.0 1121.0
HKD1_k127_1013827_1 formate dehydrogenase - - - 2.26e-230 744.0
HKD1_k127_1013827_10 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000007969 132.0
HKD1_k127_1013827_11 - - - - 0.00000000000000001398 86.0
HKD1_k127_1013827_12 - - - - 0.000000000000000228 93.0
HKD1_k127_1013827_16 Subtilase family - - - 0.0009972 45.0
HKD1_k127_1013827_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 592.0
HKD1_k127_1013827_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 539.0
HKD1_k127_1013827_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 434.0
HKD1_k127_1013827_5 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 376.0
HKD1_k127_1013827_6 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 329.0
HKD1_k127_1013827_7 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001214 241.0
HKD1_k127_1013827_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000003264 190.0
HKD1_k127_1013827_9 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000001356 164.0
HKD1_k127_1036718_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.247e-274 870.0
HKD1_k127_1036718_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 390.0
HKD1_k127_1036718_2 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 301.0
HKD1_k127_1036718_3 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006407 258.0
HKD1_k127_1036718_4 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002588 257.0
HKD1_k127_1036718_5 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000009437 216.0
HKD1_k127_1036718_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000001098 222.0
HKD1_k127_1036718_7 Belongs to the UPF0173 family - - - 0.000000000000000001123 93.0
HKD1_k127_1036718_8 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0001967 53.0
HKD1_k127_1058164_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007846 290.0
HKD1_k127_1058164_1 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000001646 201.0
HKD1_k127_1058164_2 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000005349 152.0
HKD1_k127_1058164_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000006272 92.0
HKD1_k127_1058164_4 Putative zinc-finger - - - 0.000000001615 66.0
HKD1_k127_1058164_5 Sigma-70, region 4 K03088 - - 0.0003627 47.0
HKD1_k127_1079655_0 Aminotransferase class-III - - - 3.109e-215 678.0
HKD1_k127_1079655_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 381.0
HKD1_k127_1079655_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000007696 155.0
HKD1_k127_1079655_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.000000000000000000000002898 106.0
HKD1_k127_1085521_0 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 323.0
HKD1_k127_1085521_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 319.0
HKD1_k127_1085521_2 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001165 285.0
HKD1_k127_1085521_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.000000000000000000000000000000000000001062 167.0
HKD1_k127_1085521_4 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000002574 87.0
HKD1_k127_1085521_5 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000001035 59.0
HKD1_k127_1099893_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.224e-243 781.0
HKD1_k127_1099893_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 469.0
HKD1_k127_1099893_10 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000315 286.0
HKD1_k127_1099893_11 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000001392 245.0
HKD1_k127_1099893_12 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000002021 247.0
HKD1_k127_1099893_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000008863 246.0
HKD1_k127_1099893_14 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000001116 234.0
HKD1_k127_1099893_15 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000005748 225.0
HKD1_k127_1099893_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000006367 194.0
HKD1_k127_1099893_17 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000003075 197.0
HKD1_k127_1099893_18 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000009405 177.0
HKD1_k127_1099893_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000002293 166.0
HKD1_k127_1099893_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 475.0
HKD1_k127_1099893_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000002583 159.0
HKD1_k127_1099893_21 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000174 175.0
HKD1_k127_1099893_22 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000003852 166.0
HKD1_k127_1099893_23 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000002158 138.0
HKD1_k127_1099893_24 Transglycosylase SLT domain - - - 0.00000000000000000000000000000003231 134.0
HKD1_k127_1099893_25 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000004954 123.0
HKD1_k127_1099893_26 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000617 103.0
HKD1_k127_1099893_27 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000002087 84.0
HKD1_k127_1099893_28 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000001436 77.0
HKD1_k127_1099893_29 Yip1 domain - - - 0.00000000000002427 82.0
HKD1_k127_1099893_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 434.0
HKD1_k127_1099893_30 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000001101 83.0
HKD1_k127_1099893_31 Modulates RecA activity K03565 - - 0.000000000001714 74.0
HKD1_k127_1099893_32 Belongs to the UPF0109 family K06960 - - 0.000000049 59.0
HKD1_k127_1099893_33 ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006508,GO:0006605,GO:0006625,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0016043,GO:0016485,GO:0019538,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043574,GO:0044238,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564 3.4.21.53 0.00005013 56.0
HKD1_k127_1099893_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 400.0
HKD1_k127_1099893_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 366.0
HKD1_k127_1099893_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 327.0
HKD1_k127_1099893_7 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 289.0
HKD1_k127_1099893_8 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003983 286.0
HKD1_k127_1099893_9 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002659 274.0
HKD1_k127_1106113_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 385.0
HKD1_k127_1106118_0 Protein kinase domain K12132 - 2.7.11.1 2.872e-231 745.0
HKD1_k127_1106118_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 379.0
HKD1_k127_1106118_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000003548 140.0
HKD1_k127_1124406_0 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 555.0
HKD1_k127_1124406_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 404.0
HKD1_k127_1124406_2 metallopeptidase activity - - - 0.000000000453 74.0
HKD1_k127_1142241_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0 1321.0
HKD1_k127_1142241_1 Protein conserved in bacteria K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 471.0
HKD1_k127_1142241_10 DinB family - - - 0.000000000000000000000000000000000000008578 162.0
HKD1_k127_1142241_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 410.0
HKD1_k127_1142241_3 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 376.0
HKD1_k127_1142241_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 289.0
HKD1_k127_1142241_5 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001267 281.0
HKD1_k127_1142241_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 264.0
HKD1_k127_1142241_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007487 260.0
HKD1_k127_1142241_8 gluconolactonase activity K01053,K04565 - 1.15.1.1,3.1.1.17 0.00000000000000000000000000000000000000000000000000005858 203.0
HKD1_k127_1142241_9 SMART Transcription regulator, AsnC-type K03718,K03719 - - 0.00000000000000000000000000000000000000000000001173 176.0
HKD1_k127_1150786_0 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 402.0
HKD1_k127_1150786_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000037 164.0
HKD1_k127_1150786_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000348 119.0
HKD1_k127_1150786_3 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000009219 115.0
HKD1_k127_1150786_4 Bacterial membrane protein, YfhO - - - 0.00000000000000000000001373 117.0
HKD1_k127_1150786_5 Bacterial membrane protein, YfhO - - - 0.00000000000000000006074 107.0
HKD1_k127_1150786_6 - - - - 0.0000000002547 73.0
HKD1_k127_1150786_7 - - - - 0.000005165 60.0
HKD1_k127_1150786_8 Bacterial membrane protein, YfhO - - - 0.0003282 54.0
HKD1_k127_1173201_0 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000002236 273.0
HKD1_k127_1173201_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000009568 248.0
HKD1_k127_1173201_2 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000000000000000000000000000000000000000000000000000006739 232.0
HKD1_k127_1173201_3 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000004832 188.0
HKD1_k127_1173201_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000005066 78.0
HKD1_k127_118823_0 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 1.141e-275 859.0
HKD1_k127_118823_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 2.306e-241 766.0
HKD1_k127_118823_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.732e-215 679.0
HKD1_k127_118823_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 547.0
HKD1_k127_118823_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 529.0
HKD1_k127_118823_5 lipopolysaccharide transport K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 449.0
HKD1_k127_118823_6 PFAM ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 291.0
HKD1_k127_118823_7 Domain of unknown function (DUF4136) - - - 0.000000000001869 81.0
HKD1_k127_1188951_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 621.0
HKD1_k127_1188951_1 Pkd domain containing protein K12567 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 309.0
HKD1_k127_1188951_2 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000002276 162.0
HKD1_k127_1209155_0 metalloendopeptidase activity K01283 - 3.4.15.1 2.333e-217 713.0
HKD1_k127_1209155_1 PFAM ribonuclease II K01147 - 3.1.13.1 5.249e-194 617.0
HKD1_k127_1209155_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0000000001919 64.0
HKD1_k127_1220345_0 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 579.0
HKD1_k127_1220345_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 535.0
HKD1_k127_1220345_10 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000007741 170.0
HKD1_k127_1220345_11 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000001083 162.0
HKD1_k127_1220345_12 - - - - 0.0000000000000000000000000000000003627 138.0
HKD1_k127_1220345_13 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000001642 145.0
HKD1_k127_1220345_14 Thioesterase - - - 0.00000000000000000000000000001448 124.0
HKD1_k127_1220345_15 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000323 127.0
HKD1_k127_1220345_16 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000001202 114.0
HKD1_k127_1220345_17 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000001878 80.0
HKD1_k127_1220345_19 metallopeptidase activity K20276 - - 0.00000000000001943 89.0
HKD1_k127_1220345_2 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 380.0
HKD1_k127_1220345_20 peroxiredoxin activity - - - 0.00000000001851 77.0
HKD1_k127_1220345_3 Extradiol ring-cleavage dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 315.0
HKD1_k127_1220345_4 formate dehydrogenase K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 312.0
HKD1_k127_1220345_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 316.0
HKD1_k127_1220345_6 Dystroglycan-type cadherin-like domains. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004505 297.0
HKD1_k127_1220345_7 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000147 233.0
HKD1_k127_1220345_8 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000616 171.0
HKD1_k127_1220345_9 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000001384 186.0
HKD1_k127_1222621_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000001845 191.0
HKD1_k127_1222621_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000001682 140.0
HKD1_k127_1222621_2 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000001473 136.0
HKD1_k127_1222621_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000000001578 118.0
HKD1_k127_1222621_4 PFAM ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.000000000000000000000000003337 112.0
HKD1_k127_1232564_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1262.0
HKD1_k127_1232564_1 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 534.0
HKD1_k127_1232564_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.000000000000000000000000000000000000000000000000000000003727 226.0
HKD1_k127_1232564_11 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000005258 206.0
HKD1_k127_1232564_12 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000002291 168.0
HKD1_k127_1232564_13 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000005776 61.0
HKD1_k127_1232564_14 Bacteriophage replication gene A protein (GPA) - - - 0.0000003407 57.0
HKD1_k127_1232564_2 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 500.0
HKD1_k127_1232564_3 SMART serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 533.0
HKD1_k127_1232564_4 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 480.0
HKD1_k127_1232564_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 493.0
HKD1_k127_1232564_6 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 377.0
HKD1_k127_1232564_7 COG1879 ABC-type sugar transport system, periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 330.0
HKD1_k127_1232564_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001276 318.0
HKD1_k127_1232564_9 Outer Membrane Lipoprotein K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000209 221.0
HKD1_k127_1287898_0 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 350.0
HKD1_k127_1287898_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 352.0
HKD1_k127_1287898_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000001528 217.0
HKD1_k127_1287898_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000007206 170.0
HKD1_k127_1287898_4 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000005558 126.0
HKD1_k127_1293287_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 546.0
HKD1_k127_1293287_1 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008035 255.0
HKD1_k127_1293287_2 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
HKD1_k127_1293287_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000002045 173.0
HKD1_k127_1293287_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000005757 64.0
HKD1_k127_12990_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 521.0
HKD1_k127_12990_1 Putative lumazine-binding - - - 0.00000000000000000000001278 106.0
HKD1_k127_1299856_0 glutamate decarboxylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 542.0
HKD1_k127_1299856_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 444.0
HKD1_k127_1299856_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 292.0
HKD1_k127_1299856_3 - - - - 0.000000000000000000000000000000000000000000000000000000001389 204.0
HKD1_k127_1299856_4 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000663 200.0
HKD1_k127_1299856_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000003315 194.0
HKD1_k127_1299856_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000004463 169.0
HKD1_k127_1299856_7 Haem-binding domain - - - 0.0000000000000000000000000000117 133.0
HKD1_k127_1299856_8 - - - - 0.0000000000000000000000000001858 123.0
HKD1_k127_1301899_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 9.022e-254 801.0
HKD1_k127_1301899_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 7.691e-240 753.0
HKD1_k127_1301899_10 Cytochrome c - - - 0.00000000000000000000000000000000000008888 149.0
HKD1_k127_1301899_11 Universal stress protein - - - 0.00000001343 68.0
HKD1_k127_1301899_12 receptor K02014 - - 0.0000007823 60.0
HKD1_k127_1301899_2 PFAM Leukotriene A4 hydrolase, C-terminal - - - 7.698e-211 677.0
HKD1_k127_1301899_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 490.0
HKD1_k127_1301899_4 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 462.0
HKD1_k127_1301899_5 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 339.0
HKD1_k127_1301899_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 335.0
HKD1_k127_1301899_7 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 301.0
HKD1_k127_1301899_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 261.0
HKD1_k127_1301899_9 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000007002 230.0
HKD1_k127_1303386_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 481.0
HKD1_k127_1303386_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 417.0
HKD1_k127_1303386_10 Tyrosine recombinase xerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002909 284.0
HKD1_k127_1303386_11 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 258.0
HKD1_k127_1303386_12 B12 binding domain K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005238 256.0
HKD1_k127_1303386_13 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002791 249.0
HKD1_k127_1303386_14 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000001383 251.0
HKD1_k127_1303386_15 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000009537 231.0
HKD1_k127_1303386_16 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000004303 200.0
HKD1_k127_1303386_17 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000002403 169.0
HKD1_k127_1303386_18 NUDIX domain - - - 0.0000000000000000000000000000000000000002474 156.0
HKD1_k127_1303386_19 transglycosylase K08309 - - 0.000000000000000000000000000000000492 151.0
HKD1_k127_1303386_2 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 388.0
HKD1_k127_1303386_20 Tetratricopeptide repeat - - - 0.0000000000003021 85.0
HKD1_k127_1303386_21 protein conserved in bacteria - - - 0.0003289 53.0
HKD1_k127_1303386_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 372.0
HKD1_k127_1303386_4 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 354.0
HKD1_k127_1303386_5 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 327.0
HKD1_k127_1303386_6 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 328.0
HKD1_k127_1303386_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 318.0
HKD1_k127_1303386_8 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 314.0
HKD1_k127_1303386_9 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 305.0
HKD1_k127_1337251_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 603.0
HKD1_k127_1337251_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000005091 274.0
HKD1_k127_1337251_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000001405 135.0
HKD1_k127_1337251_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000761 112.0
HKD1_k127_1337251_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000007902 87.0
HKD1_k127_1337251_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001872 67.0
HKD1_k127_1337251_14 ribosomal protein l30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000001766 68.0
HKD1_k127_1337251_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001749 258.0
HKD1_k127_1337251_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008839 212.0
HKD1_k127_1337251_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003387 205.0
HKD1_k127_1337251_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000007908 205.0
HKD1_k127_1337251_6 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000653 165.0
HKD1_k127_1337251_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000121 156.0
HKD1_k127_1337251_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000007863 153.0
HKD1_k127_1337251_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000002258 140.0
HKD1_k127_1345967_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 522.0
HKD1_k127_1345967_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
HKD1_k127_1345967_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000001343 173.0
HKD1_k127_1345967_3 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000005337 96.0
HKD1_k127_1345967_4 Domain of Unknown Function (DUF1080) - - - 0.0000002047 62.0
HKD1_k127_1352863_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 9.258e-270 842.0
HKD1_k127_1352863_1 Radical SAM - - - 1.308e-227 716.0
HKD1_k127_1352863_10 Copper resistance protein D K07245 - - 0.00000000000000001486 92.0
HKD1_k127_1352863_11 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000002923 62.0
HKD1_k127_1352863_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 359.0
HKD1_k127_1352863_3 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 333.0
HKD1_k127_1352863_4 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004596 297.0
HKD1_k127_1352863_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007722 287.0
HKD1_k127_1352863_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 267.0
HKD1_k127_1352863_7 response regulator K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000006046 226.0
HKD1_k127_1352863_8 Histidine kinase K07644,K18351 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000004483 220.0
HKD1_k127_1352863_9 membrane - - - 0.0000000000000000000000001488 124.0
HKD1_k127_140797_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 605.0
HKD1_k127_140797_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 424.0
HKD1_k127_140797_2 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 373.0
HKD1_k127_140797_3 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007225 281.0
HKD1_k127_140797_4 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000002471 198.0
HKD1_k127_140797_5 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000002851 153.0
HKD1_k127_1492315_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 391.0
HKD1_k127_1492315_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593,K13745 - 4.1.1.105,4.1.1.28,4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 388.0
HKD1_k127_1492315_10 RNA recognition motif - - - 0.00000000000000000000000000002542 119.0
HKD1_k127_1492315_11 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000001075 100.0
HKD1_k127_1492315_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000949 94.0
HKD1_k127_1492315_13 Cupin domain - - - 0.00000000000000004277 86.0
HKD1_k127_1492315_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 321.0
HKD1_k127_1492315_3 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
HKD1_k127_1492315_4 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.000000000000000000000000000000000000000000000000000000000008922 221.0
HKD1_k127_1492315_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000187 191.0
HKD1_k127_1492315_6 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000003611 191.0
HKD1_k127_1492315_7 Histidine kinase K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000003564 189.0
HKD1_k127_1492315_8 peptidase C26 K07010 - - 0.000000000000000000000000000000000000001214 156.0
HKD1_k127_1492315_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000002251 146.0
HKD1_k127_1496161_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 398.0
HKD1_k127_1496161_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005061 284.0
HKD1_k127_1496161_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000009293 269.0
HKD1_k127_1496161_3 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000000003697 222.0
HKD1_k127_1496161_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000008236 209.0
HKD1_k127_1496161_5 oxidoreductase activity K12511 - - 0.0000000000000000000000000000000000000002345 168.0
HKD1_k127_1496161_6 Peptidase family M23 K21471 - - 0.0000000000000000000000004111 123.0
HKD1_k127_1496161_7 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.000000000000000000009582 100.0
HKD1_k127_159057_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 401.0
HKD1_k127_159057_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 380.0
HKD1_k127_159057_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 317.0
HKD1_k127_159057_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001017 263.0
HKD1_k127_159057_4 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000506 269.0
HKD1_k127_159057_5 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000002849 208.0
HKD1_k127_159057_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000001307 141.0
HKD1_k127_159057_7 TIGRFAM addiction module toxin, Txe YoeB family - - - 0.00000000000000000000000000000000001433 136.0
HKD1_k127_159057_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000002062 136.0
HKD1_k127_159057_9 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000003994 116.0
HKD1_k127_1662630_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000002682 226.0
HKD1_k127_1662630_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001826 68.0
HKD1_k127_166684_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 593.0
HKD1_k127_166684_1 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005486 296.0
HKD1_k127_166684_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000001168 200.0
HKD1_k127_166684_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000009373 185.0
HKD1_k127_166684_4 YCII-related domain - - - 0.00000000000000000000001528 104.0
HKD1_k127_1704286_0 Sulfatase K01130 - 3.1.6.1 0.0 1349.0
HKD1_k127_1704286_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 8.521e-301 953.0
HKD1_k127_1704286_10 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000008315 242.0
HKD1_k127_1704286_11 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
HKD1_k127_1704286_12 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000005224 201.0
HKD1_k127_1704286_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000007315 189.0
HKD1_k127_1704286_14 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000915 182.0
HKD1_k127_1704286_15 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.0000000000000000000000000000000000000000009382 163.0
HKD1_k127_1704286_16 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000005989 147.0
HKD1_k127_1704286_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000687 140.0
HKD1_k127_1704286_18 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000002537 130.0
HKD1_k127_1704286_19 O-Antigen ligase K18814 - - 0.00000000000000000000000000008034 130.0
HKD1_k127_1704286_2 mRNA catabolic process K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 548.0
HKD1_k127_1704286_20 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000002559 87.0
HKD1_k127_1704286_21 Redoxin K03564 - 1.11.1.15 0.0000000000002814 71.0
HKD1_k127_1704286_22 Redoxin K03564 - 1.11.1.15 0.00000000001364 68.0
HKD1_k127_1704286_23 Cell division protein ZapA K09888 - - 0.00000000002181 68.0
HKD1_k127_1704286_24 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000008309 75.0
HKD1_k127_1704286_25 Belongs to the UPF0434 family K09791 - - 0.000000002033 62.0
HKD1_k127_1704286_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 550.0
HKD1_k127_1704286_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 417.0
HKD1_k127_1704286_5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 398.0
HKD1_k127_1704286_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 363.0
HKD1_k127_1704286_7 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
HKD1_k127_1704286_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 308.0
HKD1_k127_1704286_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000429 283.0
HKD1_k127_1715_0 Fungalysin metallopeptidase (M36) K01417 - - 1.074e-235 752.0
HKD1_k127_1715_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 366.0
HKD1_k127_1715_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000009286 234.0
HKD1_k127_1715_3 Beta-lactamase enzyme family K07258,K17836 - 3.4.16.4,3.5.2.6 0.0000000000000000000000000000000000005648 151.0
HKD1_k127_1715_4 Membrane - - - 0.0000000000000000000000001852 115.0
HKD1_k127_1720560_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 598.0
HKD1_k127_179852_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001349 292.0
HKD1_k127_179852_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000003997 168.0
HKD1_k127_179852_2 PFAM ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.00000000000000008265 93.0
HKD1_k127_193440_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 604.0
HKD1_k127_193440_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 327.0
HKD1_k127_1965694_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 3e-323 1023.0
HKD1_k127_1965694_1 Alpha-glucan phosphorylase K00688 - 2.4.1.1 7.95e-219 707.0
HKD1_k127_1965694_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 543.0
HKD1_k127_1965694_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 339.0
HKD1_k127_1965694_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 296.0
HKD1_k127_1965694_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 315.0
HKD1_k127_1965694_6 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000002558 145.0
HKD1_k127_1965694_7 membrane K08972 - - 0.00000000000000000000000001255 112.0
HKD1_k127_1965694_8 Tetratricopeptide repeat - - - 0.000000000001305 70.0
HKD1_k127_197379_0 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 342.0
HKD1_k127_197379_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000001198 147.0
HKD1_k127_2017529_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.144e-224 709.0
HKD1_k127_2017529_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 527.0
HKD1_k127_2017529_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000003628 235.0
HKD1_k127_2017529_11 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000559 194.0
HKD1_k127_2017529_12 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000006841 198.0
HKD1_k127_2017529_13 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000008321 192.0
HKD1_k127_2017529_14 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000001915 181.0
HKD1_k127_2017529_15 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000015 177.0
HKD1_k127_2017529_16 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.00000000000000000000000000000004703 148.0
HKD1_k127_2017529_17 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000004095 134.0
HKD1_k127_2017529_18 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000095 123.0
HKD1_k127_2017529_19 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000002749 112.0
HKD1_k127_2017529_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 499.0
HKD1_k127_2017529_20 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000007641 111.0
HKD1_k127_2017529_21 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000001018 113.0
HKD1_k127_2017529_22 DSBA-like thioredoxin domain - - - 0.00000000000000005486 93.0
HKD1_k127_2017529_23 Biotin-requiring enzyme - - - 0.00000000000002067 87.0
HKD1_k127_2017529_24 - - - - 0.000000000001162 76.0
HKD1_k127_2017529_25 Peptidase M56 - - - 0.00000000002867 75.0
HKD1_k127_2017529_26 Peptidase M56 - - - 0.00000000003405 75.0
HKD1_k127_2017529_27 Gram-negative bacterial TonB protein C-terminal - - - 0.00000003244 67.0
HKD1_k127_2017529_28 domain, Protein - - - 0.00000006564 66.0
HKD1_k127_2017529_29 Thioredoxin - - - 0.0000001083 64.0
HKD1_k127_2017529_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 443.0
HKD1_k127_2017529_31 TPR repeat - - - 0.0000001947 64.0
HKD1_k127_2017529_32 PilX N-terminal - - - 0.0000524 56.0
HKD1_k127_2017529_33 gag-polyprotein putative aspartyl protease - - - 0.0001985 54.0
HKD1_k127_2017529_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 469.0
HKD1_k127_2017529_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 461.0
HKD1_k127_2017529_6 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 390.0
HKD1_k127_2017529_7 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 362.0
HKD1_k127_2017529_8 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 350.0
HKD1_k127_2017529_9 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 315.0
HKD1_k127_2020560_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.747e-199 636.0
HKD1_k127_2020560_1 desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 312.0
HKD1_k127_2020560_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000003461 180.0
HKD1_k127_2020560_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000001754 135.0
HKD1_k127_2020560_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000545 139.0
HKD1_k127_2020560_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000005673 114.0
HKD1_k127_2020560_6 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000001408 90.0
HKD1_k127_2020560_7 Putative serine dehydratase domain - - - 0.00000000000008966 73.0
HKD1_k127_2020560_8 von Willebrand factor, type A K07114 - - 0.000000007501 67.0
HKD1_k127_2032928_0 asparagine synthase K01953 - 6.3.5.4 4.239e-194 614.0
HKD1_k127_2032928_1 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 552.0
HKD1_k127_2032928_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 310.0
HKD1_k127_2032928_3 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007006 261.0
HKD1_k127_2035898_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 570.0
HKD1_k127_2035898_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 542.0
HKD1_k127_2035898_10 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006393 264.0
HKD1_k127_2035898_11 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003483 273.0
HKD1_k127_2035898_12 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000002978 247.0
HKD1_k127_2035898_13 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002123 236.0
HKD1_k127_2035898_14 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000002501 219.0
HKD1_k127_2035898_15 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000001544 209.0
HKD1_k127_2035898_16 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000004758 177.0
HKD1_k127_2035898_17 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000006036 181.0
HKD1_k127_2035898_18 AI-2E family transporter - - - 0.00000000000000000000000000000000008703 148.0
HKD1_k127_2035898_19 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000003241 143.0
HKD1_k127_2035898_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 513.0
HKD1_k127_2035898_20 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000001788 132.0
HKD1_k127_2035898_21 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000847 133.0
HKD1_k127_2035898_22 phosphorelay signal transduction system - - - 0.0000000000000000000000000002424 126.0
HKD1_k127_2035898_23 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000008978 112.0
HKD1_k127_2035898_24 chlorophyll binding - - - 0.000000000000000000837 100.0
HKD1_k127_2035898_25 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.000000000000000002441 99.0
HKD1_k127_2035898_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 400.0
HKD1_k127_2035898_4 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 365.0
HKD1_k127_2035898_5 PFAM Formiminotransferase K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 345.0
HKD1_k127_2035898_6 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 360.0
HKD1_k127_2035898_7 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 302.0
HKD1_k127_2035898_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000188 289.0
HKD1_k127_2035898_9 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007786 282.0
HKD1_k127_2037776_0 DEAD DEAH box K03724 - - 0.0 1857.0
HKD1_k127_2037776_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.231e-305 954.0
HKD1_k127_2037776_10 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000002903 185.0
HKD1_k127_2037776_11 Chaperone of endosialidase - - - 0.000000000000000000000000000000000000000005106 172.0
HKD1_k127_2037776_12 - - - - 0.00000000000000000000000000000000000000002312 169.0
HKD1_k127_2037776_13 glyoxalase III activity - - - 0.0000000000000000000000000000000000005066 148.0
HKD1_k127_2037776_14 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000001049 153.0
HKD1_k127_2037776_15 - - - - 0.000000000000000000000000000000009822 135.0
HKD1_k127_2037776_16 Permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000001288 129.0
HKD1_k127_2037776_17 - - - - 0.000000000000000002277 91.0
HKD1_k127_2037776_18 Tyrosine phosphatase family - - - 0.000000000003222 76.0
HKD1_k127_2037776_2 PFAM Glycoside hydrolase 15-related K01178 - 3.2.1.3 5.004e-274 854.0
HKD1_k127_2037776_20 - - - - 0.00000001312 62.0
HKD1_k127_2037776_22 Winged helix-turn helix - - - 0.000003051 55.0
HKD1_k127_2037776_26 UPF0391 membrane protein - - - 0.0007563 44.0
HKD1_k127_2037776_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.052e-267 854.0
HKD1_k127_2037776_4 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 411.0
HKD1_k127_2037776_5 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 405.0
HKD1_k127_2037776_6 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000339 291.0
HKD1_k127_2037776_7 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000008431 228.0
HKD1_k127_2037776_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000002014 236.0
HKD1_k127_2037776_9 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000001951 201.0
HKD1_k127_2040466_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 621.0
HKD1_k127_2062801_0 Prolyl oligopeptidase - - - 1.838e-254 800.0
HKD1_k127_2062801_1 Involved in the tonB-independent uptake of proteins - - - 1.552e-212 694.0
HKD1_k127_2062801_10 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 390.0
HKD1_k127_2062801_11 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 396.0
HKD1_k127_2062801_12 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 368.0
HKD1_k127_2062801_13 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 326.0
HKD1_k127_2062801_14 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007999 299.0
HKD1_k127_2062801_15 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007161 276.0
HKD1_k127_2062801_16 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000002262 201.0
HKD1_k127_2062801_17 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10036 - - 0.00000000000000000000000000000000000000000000000000000005401 224.0
HKD1_k127_2062801_18 gluconolactonase activity K01053,K04565 - 1.15.1.1,3.1.1.17 0.000000000000000000000000000000000000000000000000000003659 210.0
HKD1_k127_2062801_19 COGs COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) K04047 - - 0.000000000000000000000000000000000000000000000000003793 192.0
HKD1_k127_2062801_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 1.443e-211 675.0
HKD1_k127_2062801_20 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000004128 189.0
HKD1_k127_2062801_21 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000001113 176.0
HKD1_k127_2062801_22 DinB family - - - 0.0000000000000000000000000000000000001609 153.0
HKD1_k127_2062801_23 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000001163 143.0
HKD1_k127_2062801_24 Citrate transporter - - - 0.000000000000000000000000000003393 134.0
HKD1_k127_2062801_25 PFAM PIN domain - - - 0.0000000000000000000000000004768 121.0
HKD1_k127_2062801_26 EamA-like transporter family - - - 0.00000000000000000000000009825 111.0
HKD1_k127_2062801_27 Domain of unknown function (DUF4412) - - - 0.000000000000000002925 101.0
HKD1_k127_2062801_28 positive regulation of growth - - - 0.0000000000000001466 93.0
HKD1_k127_2062801_29 Transcriptional regulator - - - 0.0000000000000001637 94.0
HKD1_k127_2062801_3 Ammonium Transporter K03320 - - 7.628e-202 636.0
HKD1_k127_2062801_30 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000001261 72.0
HKD1_k127_2062801_31 FHA domain - - - 0.0000001251 65.0
HKD1_k127_2062801_4 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 611.0
HKD1_k127_2062801_5 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 489.0
HKD1_k127_2062801_6 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 481.0
HKD1_k127_2062801_7 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 492.0
HKD1_k127_2062801_8 Peptidase family M49 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 473.0
HKD1_k127_2062801_9 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 448.0
HKD1_k127_2067234_0 DEAD DEAH box helicase K03724 - - 0.0 1304.0
HKD1_k127_2067234_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 383.0
HKD1_k127_2067234_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
HKD1_k127_2067234_3 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000337 258.0
HKD1_k127_2079077_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1195.0
HKD1_k127_2079077_1 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000001047 140.0
HKD1_k127_2079077_2 domain, Protein - - - 0.0000000000000000000003825 115.0
HKD1_k127_2079077_3 exo-alpha-(2->6)-sialidase activity - - - 0.00000000008249 77.0
HKD1_k127_2079077_4 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000004317 61.0
HKD1_k127_2086945_0 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 410.0
HKD1_k127_2086945_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 353.0
HKD1_k127_2086945_2 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000009467 181.0
HKD1_k127_2086945_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000001648 123.0
HKD1_k127_2087073_0 Protein of unknown function, DUF255 K06888 - - 1.147e-201 649.0
HKD1_k127_2087073_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 450.0
HKD1_k127_2087073_10 PFAM phosphatidate cytidylyltransferase - - - 0.000596 52.0
HKD1_k127_2087073_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 404.0
HKD1_k127_2087073_3 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008225 348.0
HKD1_k127_2087073_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000001892 243.0
HKD1_k127_2087073_5 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000005644 205.0
HKD1_k127_2087073_6 membrane - GO:0005575,GO:0016020 - 0.00000000000000000000001283 115.0
HKD1_k127_2087073_7 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000002183 98.0
HKD1_k127_2087073_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00172,K00441,K03522 - 1.12.98.1,1.2.7.1 0.000000000006813 77.0
HKD1_k127_2087073_9 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000006877 76.0
HKD1_k127_2089072_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 316.0
HKD1_k127_2089072_1 Domain of unknown function (DUF4070) - - - 0.00000000000002526 75.0
HKD1_k127_2096168_0 Involved in the tonB-independent uptake of proteins - - - 2.696e-226 730.0
HKD1_k127_2096168_1 Involved in the tonB-independent uptake of proteins - - - 1.318e-225 732.0
HKD1_k127_2096168_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 381.0
HKD1_k127_2096168_3 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 281.0
HKD1_k127_2096168_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008743,GO:0009066,GO:0009987,GO:0016043,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000001608 273.0
HKD1_k127_2096168_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000003088 201.0
HKD1_k127_2096168_6 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000009289 137.0
HKD1_k127_2096168_7 - - - - 0.000000000000000000000000002113 122.0
HKD1_k127_2096168_8 RNA recognition motif - - - 0.0000000000000000000000001922 109.0
HKD1_k127_2096168_9 Lysin motif - - - 0.00000000000000000003153 93.0
HKD1_k127_2106094_0 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000011 228.0
HKD1_k127_2106094_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000009198 109.0
HKD1_k127_2106812_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 549.0
HKD1_k127_2106812_1 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 526.0
HKD1_k127_2106812_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 374.0
HKD1_k127_2106812_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 339.0
HKD1_k127_2106812_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003034 289.0
HKD1_k127_2106812_5 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000009328 211.0
HKD1_k127_2106812_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000005053 218.0
HKD1_k127_2106812_7 Peptidase family M1 domain - - - 0.000000000000000000003592 109.0
HKD1_k127_2131445_0 amine dehydrogenase activity - - - 0.00000000000000000000000000001507 131.0
HKD1_k127_2131445_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000003174 103.0
HKD1_k127_2131445_2 Outer membrane efflux protein K18904 - - 0.0001721 53.0
HKD1_k127_2136502_0 PFAM tRNA synthetase class II (D K and N), nucleic acid binding OB-fold tRNA helicase-type K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 544.0
HKD1_k127_2136502_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 514.0
HKD1_k127_2136502_10 methyltransferase activity K04786,K12240,K13613,K15677 - - 0.0000000000000000008076 96.0
HKD1_k127_2136502_11 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000003703 64.0
HKD1_k127_2136502_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001983 286.0
HKD1_k127_2136502_3 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003611 233.0
HKD1_k127_2136502_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
HKD1_k127_2136502_5 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000007646 233.0
HKD1_k127_2136502_6 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000001953 193.0
HKD1_k127_2136502_7 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000001579 151.0
HKD1_k127_2136502_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07675 - 2.7.13.3 0.00000000000000000000000000000000000002125 158.0
HKD1_k127_2136502_9 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000003086 141.0
HKD1_k127_213949_0 Large extracellular alpha-helical protein - - - 0.0 1205.0
HKD1_k127_213949_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004632 293.0
HKD1_k127_2145224_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 5.715e-279 865.0
HKD1_k127_2145224_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 608.0
HKD1_k127_2145224_10 TspO/MBR family K05770 - - 0.000000000000000000000000000271 126.0
HKD1_k127_2145224_2 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 602.0
HKD1_k127_2145224_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 474.0
HKD1_k127_2145224_4 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 451.0
HKD1_k127_2145224_5 DNA photolyase domain protein K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 381.0
HKD1_k127_2145224_6 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001368 258.0
HKD1_k127_2145224_7 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000003511 246.0
HKD1_k127_2145224_8 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000001054 196.0
HKD1_k127_2145224_9 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000005771 149.0
HKD1_k127_2165771_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 514.0
HKD1_k127_2165771_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 445.0
HKD1_k127_2165771_10 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006185 282.0
HKD1_k127_2165771_11 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001798 247.0
HKD1_k127_2165771_12 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000003466 205.0
HKD1_k127_2165771_13 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000004905 205.0
HKD1_k127_2165771_14 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000001168 190.0
HKD1_k127_2165771_15 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000004098 187.0
HKD1_k127_2165771_16 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000002039 157.0
HKD1_k127_2165771_17 Urate oxidase N-terminal - - - 0.000000000000000000000000000000001854 148.0
HKD1_k127_2165771_18 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000007091 116.0
HKD1_k127_2165771_19 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000000000001187 112.0
HKD1_k127_2165771_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 376.0
HKD1_k127_2165771_20 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000003783 118.0
HKD1_k127_2165771_21 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000001673 95.0
HKD1_k127_2165771_22 Psort location Cytoplasmic, score - - - 0.0000000000000001153 81.0
HKD1_k127_2165771_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 365.0
HKD1_k127_2165771_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 359.0
HKD1_k127_2165771_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 329.0
HKD1_k127_2165771_6 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 337.0
HKD1_k127_2165771_7 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 305.0
HKD1_k127_2165771_8 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 317.0
HKD1_k127_2165771_9 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 295.0
HKD1_k127_2184397_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 466.0
HKD1_k127_2184397_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 433.0
HKD1_k127_2184397_2 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 422.0
HKD1_k127_2184397_3 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 343.0
HKD1_k127_221165_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.066e-208 668.0
HKD1_k127_221165_1 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 377.0
HKD1_k127_221165_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 335.0
HKD1_k127_221165_3 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000003117 233.0
HKD1_k127_221165_4 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000001567 237.0
HKD1_k127_221165_5 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000195 213.0
HKD1_k127_221165_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000004004 192.0
HKD1_k127_2230035_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.324e-241 770.0
HKD1_k127_2230035_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 488.0
HKD1_k127_2230035_10 Protein of unknown function (DUF3052) - - - 0.000002413 56.0
HKD1_k127_2230035_11 Glycosyl transferase family 41 - - - 0.0003865 49.0
HKD1_k127_2230035_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 430.0
HKD1_k127_2230035_3 threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 344.0
HKD1_k127_2230035_5 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001342 253.0
HKD1_k127_2230035_6 conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004663 247.0
HKD1_k127_2230035_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000008639 201.0
HKD1_k127_2230035_8 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000002351 134.0
HKD1_k127_2230035_9 Cytochrome c - - - 0.00000000008708 74.0
HKD1_k127_224188_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.12e-199 630.0
HKD1_k127_224188_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 329.0
HKD1_k127_224188_2 Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine K01761 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 313.0
HKD1_k127_224188_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002971 252.0
HKD1_k127_224188_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002 239.0
HKD1_k127_224188_5 PFAM phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000119 239.0
HKD1_k127_224188_6 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002404 233.0
HKD1_k127_224188_7 - - - - 0.000000000000000000000000000000000000000000000000000001083 205.0
HKD1_k127_224188_8 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000134 119.0
HKD1_k127_2277430_0 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000001819 273.0
HKD1_k127_2277430_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000005911 264.0
HKD1_k127_2277430_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000004628 210.0
HKD1_k127_2277430_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000003412 174.0
HKD1_k127_2277430_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000001142 79.0
HKD1_k127_2278765_0 E1-E2 ATPase K01535 - 3.6.3.6 7.017e-282 887.0
HKD1_k127_2278765_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.174e-194 630.0
HKD1_k127_2278765_10 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000001605 164.0
HKD1_k127_2278765_11 Thioesterase superfamily - - - 0.0000000000000000000000000000001086 130.0
HKD1_k127_2278765_12 - - - - 0.000000000000000000000000000008235 122.0
HKD1_k127_2278765_13 - - - - 0.0000000000000000000000000002063 117.0
HKD1_k127_2278765_16 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000007237 99.0
HKD1_k127_2278765_17 Phospholipid methyltransferase - - - 0.000000000000000001643 95.0
HKD1_k127_2278765_18 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000001757 87.0
HKD1_k127_2278765_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001821 259.0
HKD1_k127_2278765_20 PFAM Methyltransferase domain - - - 0.00000000000004056 84.0
HKD1_k127_2278765_21 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03789,K03790,K03896 - 2.3.1.102,2.3.1.128 0.000000004708 68.0
HKD1_k127_2278765_22 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000003509 62.0
HKD1_k127_2278765_24 PFAM Polyketide cyclase dehydrase - - - 0.000001031 63.0
HKD1_k127_2278765_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000001215 233.0
HKD1_k127_2278765_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000002836 202.0
HKD1_k127_2278765_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000004485 202.0
HKD1_k127_2278765_6 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001345 194.0
HKD1_k127_2278765_7 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000004033 190.0
HKD1_k127_2278765_8 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000007048 177.0
HKD1_k127_2278765_9 - - - - 0.0000000000000000000000000000000000000000004261 176.0
HKD1_k127_2285995_0 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
HKD1_k127_2285995_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 433.0
HKD1_k127_2285995_2 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000004684 245.0
HKD1_k127_2285995_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000001982 180.0
HKD1_k127_2285995_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000145 152.0
HKD1_k127_2285995_5 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000003432 141.0
HKD1_k127_2285995_6 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000002718 117.0
HKD1_k127_2285995_7 cellulose binding - - - 0.00000000000000007033 94.0
HKD1_k127_2285995_8 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000005641 81.0
HKD1_k127_2290688_0 PFAM amidohydrolase - - - 3.853e-196 635.0
HKD1_k127_2290688_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 571.0
HKD1_k127_2290688_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000002667 123.0
HKD1_k127_2290688_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000395 91.0
HKD1_k127_2290688_14 TIGRFAM outer membrane autotransporter barrel domain - - - 0.0002368 47.0
HKD1_k127_2290688_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 531.0
HKD1_k127_2290688_3 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
HKD1_k127_2290688_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000004898 241.0
HKD1_k127_2290688_5 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000001222 216.0
HKD1_k127_2290688_6 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001616 213.0
HKD1_k127_2290688_7 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
HKD1_k127_2290688_8 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000001217 178.0
HKD1_k127_2290688_9 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000009217 161.0
HKD1_k127_2309793_0 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 471.0
HKD1_k127_2309793_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 388.0
HKD1_k127_2309793_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
HKD1_k127_2314035_0 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 611.0
HKD1_k127_2314035_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009835 290.0
HKD1_k127_2314035_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000008758 250.0
HKD1_k127_2314035_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000004522 212.0
HKD1_k127_2314035_4 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000002102 174.0
HKD1_k127_2314035_5 ECF sigma factor K03088 - - 0.000000000000000000000004395 111.0
HKD1_k127_2314035_6 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.0000000000000000000004938 112.0
HKD1_k127_2330244_0 Carboxypeptidase regulatory-like domain - - - 2.057e-207 681.0
HKD1_k127_2330244_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007964 287.0
HKD1_k127_2330244_10 Uncharacterised protein family (UPF0158) - - - 0.00002395 55.0
HKD1_k127_2330244_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000001062 229.0
HKD1_k127_2330244_3 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000003643 239.0
HKD1_k127_2330244_4 - - - - 0.000000000000000000000000000000000000000000001343 173.0
HKD1_k127_2330244_5 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000004172 171.0
HKD1_k127_2330244_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000003985 138.0
HKD1_k127_2330244_7 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000003097 120.0
HKD1_k127_2330244_8 Radical SAM superfamily - - - 0.00000000000000000000002128 113.0
HKD1_k127_2348399_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 508.0
HKD1_k127_2348399_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 520.0
HKD1_k127_2348399_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 407.0
HKD1_k127_2348399_4 - - - - 0.00000000000000000000000000002296 137.0
HKD1_k127_2348399_5 Bacterial membrane protein YfhO - - - 0.000000000007547 79.0
HKD1_k127_2348399_6 PFAM Oligosaccharyl transferase STT3 subunit K07151 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0045229,GO:0045232,GO:0071840 2.4.99.18 0.0000000001896 71.0
HKD1_k127_2348399_7 - - - - 0.0000004732 63.0
HKD1_k127_2350211_0 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 393.0
HKD1_k127_2350211_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000004438 256.0
HKD1_k127_2350211_2 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000002429 182.0
HKD1_k127_2352946_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 374.0
HKD1_k127_2352946_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000365 301.0
HKD1_k127_2352946_2 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001035 262.0
HKD1_k127_2359580_0 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 411.0
HKD1_k127_2359580_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000002947 201.0
HKD1_k127_2359580_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000007749 173.0
HKD1_k127_2359580_3 Domain of unknown function (DUF1949) - - - 0.0000000000000000000000000001971 132.0
HKD1_k127_2359580_4 - - - - 0.000000000000000000000000006104 128.0
HKD1_k127_2359580_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000002427 89.0
HKD1_k127_2359580_6 Preprotein translocase SecG subunit K03075 - - 0.000000000000008603 80.0
HKD1_k127_2377077_0 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000001094 222.0
HKD1_k127_2377077_1 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000001286 100.0
HKD1_k127_2377077_2 Tricorn protease C1 domain K03797 - 3.4.21.102 0.0000000000000000000001817 111.0
HKD1_k127_2377077_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000008661 71.0
HKD1_k127_2391148_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 357.0
HKD1_k127_2391148_1 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 343.0
HKD1_k127_2391148_2 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000008046 215.0
HKD1_k127_2391148_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000002774 150.0
HKD1_k127_2391148_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000009048 58.0
HKD1_k127_2407098_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 1.345e-197 632.0
HKD1_k127_2407098_1 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 446.0
HKD1_k127_2407098_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000004298 152.0
HKD1_k127_2407098_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000007615 124.0
HKD1_k127_2407098_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000001412 104.0
HKD1_k127_2407098_13 - - - - 0.00000000000006208 82.0
HKD1_k127_2407098_14 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000006474 80.0
HKD1_k127_2407098_2 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 384.0
HKD1_k127_2407098_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000004209 257.0
HKD1_k127_2407098_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000002167 223.0
HKD1_k127_2407098_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000001482 182.0
HKD1_k127_2407098_6 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000002273 166.0
HKD1_k127_2407098_7 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000001357 177.0
HKD1_k127_2407098_8 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000001814 169.0
HKD1_k127_2407098_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000008727 164.0
HKD1_k127_2411377_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 404.0
HKD1_k127_2411377_1 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 315.0
HKD1_k127_2411377_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000000485 204.0
HKD1_k127_2411377_3 DoxX family K15977 - - 0.00000000000000000000000000000000000000000000000003273 192.0
HKD1_k127_2411377_4 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000000001096 127.0
HKD1_k127_2411377_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000001221 130.0
HKD1_k127_2411377_6 - - - - 0.00000000006944 66.0
HKD1_k127_2411377_7 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000003843 68.0
HKD1_k127_2411377_8 Putative addiction module component - - - 0.0000000118 59.0
HKD1_k127_2414013_0 lipopolysaccharide transport K22110 - - 0.0 1419.0
HKD1_k127_2414013_1 Amylo-alpha-1,6-glucosidase - - - 8.461e-257 807.0
HKD1_k127_2414013_2 choline dehydrogenase activity - - - 3.196e-237 740.0
HKD1_k127_2414013_3 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 537.0
HKD1_k127_2414013_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 514.0
HKD1_k127_2414013_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 383.0
HKD1_k127_2414013_6 DoxX-like family K15977 - - 0.00002387 48.0
HKD1_k127_2431833_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 601.0
HKD1_k127_2431833_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 452.0
HKD1_k127_2431833_2 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004782 248.0
HKD1_k127_247338_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 6.425e-292 949.0
HKD1_k127_247338_1 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000645 240.0
HKD1_k127_247338_2 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000009172 230.0
HKD1_k127_247338_3 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000002884 225.0
HKD1_k127_2498206_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 380.0
HKD1_k127_2498206_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000008654 237.0
HKD1_k127_2498206_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000000001046 209.0
HKD1_k127_2498206_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000000001445 128.0
HKD1_k127_2498206_4 Short repeat of unknown function (DUF308) - - - 0.00000000000000002581 84.0
HKD1_k127_2498206_5 YbbR-like protein - - - 0.00000000000000007325 92.0
HKD1_k127_2500891_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 5.027e-207 661.0
HKD1_k127_2500891_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 539.0
HKD1_k127_2500891_10 Glycosyltransferase family 9 (heptosyltransferase) K02517 - 2.3.1.241 0.0000000000000000000001682 101.0
HKD1_k127_2500891_2 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 468.0
HKD1_k127_2500891_3 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 444.0
HKD1_k127_2500891_4 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001269 287.0
HKD1_k127_2500891_5 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000003801 232.0
HKD1_k127_2500891_6 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000005144 220.0
HKD1_k127_2500891_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000004593 188.0
HKD1_k127_2500891_8 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000004416 155.0
HKD1_k127_2500891_9 acr, cog1430 K09005 - - 0.00000000000000000000000008165 124.0
HKD1_k127_2528986_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.256e-267 847.0
HKD1_k127_2528986_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.076e-234 737.0
HKD1_k127_2528986_10 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 408.0
HKD1_k127_2528986_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 359.0
HKD1_k127_2528986_12 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 367.0
HKD1_k127_2528986_13 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 347.0
HKD1_k127_2528986_14 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 310.0
HKD1_k127_2528986_15 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 302.0
HKD1_k127_2528986_16 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 299.0
HKD1_k127_2528986_17 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009187 304.0
HKD1_k127_2528986_18 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001181 278.0
HKD1_k127_2528986_19 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000942 308.0
HKD1_k127_2528986_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.337e-232 788.0
HKD1_k127_2528986_20 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009218 274.0
HKD1_k127_2528986_21 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005051 284.0
HKD1_k127_2528986_22 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003834 260.0
HKD1_k127_2528986_23 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006231 258.0
HKD1_k127_2528986_24 PFAM sugar transferase K13012 - - 0.00000000000000000000000000000000000000000000000000000000000000000003623 254.0
HKD1_k127_2528986_25 dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000006209 245.0
HKD1_k127_2528986_26 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000003241 239.0
HKD1_k127_2528986_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000003591 240.0
HKD1_k127_2528986_28 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000005361 233.0
HKD1_k127_2528986_29 Peptidase S53 propeptide K08677 - - 0.00000000000000000000000000000000000000000000000000000003425 218.0
HKD1_k127_2528986_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 626.0
HKD1_k127_2528986_30 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000001574 195.0
HKD1_k127_2528986_31 L-serine dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000002995 199.0
HKD1_k127_2528986_32 transferase activity, transferring glycosyl groups K00786 - - 0.00000000000000000000000000000000000000000000000000001311 203.0
HKD1_k127_2528986_33 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000001415 201.0
HKD1_k127_2528986_34 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000001649 190.0
HKD1_k127_2528986_35 - - - - 0.0000000000000000000000000000000000000000000000007938 186.0
HKD1_k127_2528986_36 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000003607 193.0
HKD1_k127_2528986_37 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000001058 156.0
HKD1_k127_2528986_38 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000002328 160.0
HKD1_k127_2528986_39 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000001316 167.0
HKD1_k127_2528986_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 583.0
HKD1_k127_2528986_40 Transmembrane and TPR repeat-containing protein - - - 0.0000000000000000000000000000000000001206 164.0
HKD1_k127_2528986_41 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000004828 154.0
HKD1_k127_2528986_42 MlaD protein K02067 - - 0.00000000000000000000000000000000001287 153.0
HKD1_k127_2528986_43 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000001782 141.0
HKD1_k127_2528986_44 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000006411 148.0
HKD1_k127_2528986_45 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000471 139.0
HKD1_k127_2528986_46 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000001767 119.0
HKD1_k127_2528986_47 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000001065 130.0
HKD1_k127_2528986_48 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.00000000000000000000000001839 124.0
HKD1_k127_2528986_49 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000002588 123.0
HKD1_k127_2528986_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 522.0
HKD1_k127_2528986_50 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000003787 121.0
HKD1_k127_2528986_51 - - - - 0.0000000000000000000007276 109.0
HKD1_k127_2528986_52 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000001196 107.0
HKD1_k127_2528986_53 Domain of unknown function (DUF4340) - - - 0.000000000000000000005687 109.0
HKD1_k127_2528986_54 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000008629 85.0
HKD1_k127_2528986_55 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000004661 81.0
HKD1_k127_2528986_56 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000003765 83.0
HKD1_k127_2528986_57 Thioredoxin-like - - - 0.0000000000384 72.0
HKD1_k127_2528986_58 SNARE associated Golgi protein - - - 0.00000000003951 64.0
HKD1_k127_2528986_59 Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis K08906 - - 0.0000001293 58.0
HKD1_k127_2528986_6 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 529.0
HKD1_k127_2528986_60 Polymerase - - - 0.0004706 52.0
HKD1_k127_2528986_61 - - - - 0.0004976 53.0
HKD1_k127_2528986_7 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 511.0
HKD1_k127_2528986_8 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 490.0
HKD1_k127_2528986_9 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 461.0
HKD1_k127_2534822_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 503.0
HKD1_k127_2541933_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.753e-273 872.0
HKD1_k127_2541933_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.627e-216 687.0
HKD1_k127_2541933_10 peptidase - - - 0.0000000000000000000000000000000000000000000000000000002438 213.0
HKD1_k127_2541933_11 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000001647 196.0
HKD1_k127_2541933_12 spore germination - - - 0.00000000000000000000000000000000000000000000003143 188.0
HKD1_k127_2541933_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000001234 134.0
HKD1_k127_2541933_14 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000001639 136.0
HKD1_k127_2541933_15 regulation of translation K03530 - - 0.00000000000000000000000000001179 137.0
HKD1_k127_2541933_16 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000001527 134.0
HKD1_k127_2541933_17 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.00000000000000000000000002869 127.0
HKD1_k127_2541933_18 Thioesterase superfamily - - - 0.000000000000000000000000139 115.0
HKD1_k127_2541933_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000002128 94.0
HKD1_k127_2541933_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 551.0
HKD1_k127_2541933_20 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000386 92.0
HKD1_k127_2541933_21 peptidyl-tyrosine sulfation - - - 0.00000000005757 74.0
HKD1_k127_2541933_22 oxidoreductase activity - - - 0.00000006458 66.0
HKD1_k127_2541933_3 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 428.0
HKD1_k127_2541933_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 382.0
HKD1_k127_2541933_5 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 343.0
HKD1_k127_2541933_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000003194 251.0
HKD1_k127_2541933_7 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 228.0
HKD1_k127_2541933_8 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000001657 243.0
HKD1_k127_2541933_9 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000004162 241.0
HKD1_k127_2561332_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002931 275.0
HKD1_k127_2561332_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001872 268.0
HKD1_k127_2561332_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001544 250.0
HKD1_k127_2561332_3 cAMP biosynthetic process - - - 0.00000000001646 69.0
HKD1_k127_2580335_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 477.0
HKD1_k127_2580335_1 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 328.0
HKD1_k127_2580335_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000005322 189.0
HKD1_k127_2580335_11 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000259 182.0
HKD1_k127_2580335_12 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000115 184.0
HKD1_k127_2580335_13 ABC-2 type transporter K01992,K09690,K09691,K09692 - - 0.00000000000000000000000000000000000000008544 161.0
HKD1_k127_2580335_14 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000012 155.0
HKD1_k127_2580335_15 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000007758 162.0
HKD1_k127_2580335_16 Ion transport 2 domain protein - - - 0.000000000000000000000000000000000002449 159.0
HKD1_k127_2580335_17 methyltransferase activity K15256 - - 0.0000000000000000000000000553 125.0
HKD1_k127_2580335_18 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000009901 123.0
HKD1_k127_2580335_19 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000268 110.0
HKD1_k127_2580335_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004151 294.0
HKD1_k127_2580335_20 antisigma factor binding - - - 0.000000000000000000002683 102.0
HKD1_k127_2580335_21 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000001904 103.0
HKD1_k127_2580335_22 Glycosyl transferase, family 2 - - - 0.000000000000000002931 100.0
HKD1_k127_2580335_23 transferase activity, transferring glycosyl groups - - - 0.0000000000015 81.0
HKD1_k127_2580335_24 Acetyltransferase (GNAT) domain - - - 0.0000000005719 73.0
HKD1_k127_2580335_25 Periplasmic copper-binding protein (NosD) - - - 0.00000003051 68.0
HKD1_k127_2580335_26 Protein kinase domain K12132 - 2.7.11.1 0.000001555 61.0
HKD1_k127_2580335_27 transcriptional regulator, SARP family - - - 0.000009078 57.0
HKD1_k127_2580335_28 Helix-turn-helix - - - 0.00002185 58.0
HKD1_k127_2580335_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000004137 266.0
HKD1_k127_2580335_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002861 237.0
HKD1_k127_2580335_5 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000009108 228.0
HKD1_k127_2580335_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000004164 206.0
HKD1_k127_2580335_7 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000209 211.0
HKD1_k127_2580335_8 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000001553 208.0
HKD1_k127_2580335_9 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000000000000000000000000000000000001485 207.0
HKD1_k127_2613702_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 322.0
HKD1_k127_2613702_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008919 241.0
HKD1_k127_2613702_2 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000002563 188.0
HKD1_k127_2613702_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000261 96.0
HKD1_k127_2617265_0 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
HKD1_k127_2617265_1 Alanine racemase K20757 - 4.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002202 273.0
HKD1_k127_2617265_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000194 182.0
HKD1_k127_2675472_0 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000001314 211.0
HKD1_k127_2675472_1 Histidine kinase - - - 0.000000000000000000000000000000000000000002605 170.0
HKD1_k127_2675472_2 Acetyltransferase (GNAT) domain - - - 0.000000000000009866 75.0
HKD1_k127_2734760_0 imidazolonepropionase activity K01443 - 3.5.1.25 6.75e-207 674.0
HKD1_k127_2734760_1 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 325.0
HKD1_k127_2734760_2 Protein of unknown function (DUF2911) - - - 0.00000000000000007098 92.0
HKD1_k127_2734760_3 aminopeptidase activity K07004 - - 0.000000003009 72.0
HKD1_k127_27497_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 4.656e-232 729.0
HKD1_k127_27497_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 1.093e-220 700.0
HKD1_k127_27497_2 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 432.0
HKD1_k127_27497_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005128 294.0
HKD1_k127_27497_4 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
HKD1_k127_27497_5 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000002346 192.0
HKD1_k127_27497_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000001391 131.0
HKD1_k127_27497_7 - - - - 0.0000000000000000000000003783 118.0
HKD1_k127_27497_8 Sporulation and spore germination - - - 0.0000000000005474 83.0
HKD1_k127_27497_9 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000008102 63.0
HKD1_k127_2774415_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 445.0
HKD1_k127_2774415_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000001083 237.0
HKD1_k127_2774415_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000002969 159.0
HKD1_k127_2774415_3 - - - - 0.00000000000000000000000001492 114.0
HKD1_k127_2774415_4 LAO AO transport system ATPase K07588 - - 0.000000000000000000000003485 106.0
HKD1_k127_2774415_5 - - - - 0.00000000000001182 85.0
HKD1_k127_2796513_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1260.0
HKD1_k127_2796513_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 3.667e-295 924.0
HKD1_k127_2796513_10 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 332.0
HKD1_k127_2796513_11 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002855 302.0
HKD1_k127_2796513_12 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001077 258.0
HKD1_k127_2796513_13 PFAM Hly-III family protein K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006756 242.0
HKD1_k127_2796513_14 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
HKD1_k127_2796513_15 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000003486 239.0
HKD1_k127_2796513_16 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000111 193.0
HKD1_k127_2796513_17 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000002927 184.0
HKD1_k127_2796513_18 ABC transporter K01990 - - 0.00000000000000000000000000000000000002574 166.0
HKD1_k127_2796513_19 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000001852 149.0
HKD1_k127_2796513_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 603.0
HKD1_k127_2796513_20 signal transduction histidine kinase K07642 - 2.7.13.3 0.000000000000000000000001674 117.0
HKD1_k127_2796513_21 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000002798 107.0
HKD1_k127_2796513_22 PFAM secretion protein HlyD K02005 - - 0.00000000000000000007405 101.0
HKD1_k127_2796513_23 Transcriptional regulator - - - 0.000000000000000001581 93.0
HKD1_k127_2796513_24 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000001234 94.0
HKD1_k127_2796513_25 Bacterial regulatory proteins, tetR family - - - 0.000000000000007746 82.0
HKD1_k127_2796513_26 Putative phosphatase (DUF442) - - - 0.000000000001575 76.0
HKD1_k127_2796513_27 ATPase activity, coupled to transmembrane movement of substances K02120 - - 0.000000000005593 74.0
HKD1_k127_2796513_28 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000004471 68.0
HKD1_k127_2796513_29 PFAM Oxidoreductase, molybdopterin binding - - - 0.000000001108 66.0
HKD1_k127_2796513_3 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 498.0
HKD1_k127_2796513_31 - - - - 0.00002074 52.0
HKD1_k127_2796513_32 WD40 repeats - - - 0.0004506 54.0
HKD1_k127_2796513_33 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0006094 51.0
HKD1_k127_2796513_34 polyamine oxidase 5 K12259 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016647,GO:0040034,GO:0044424,GO:0044464,GO:0048506,GO:0048509,GO:0048510,GO:0050789,GO:0050793,GO:0055114,GO:0065007,GO:1990534 1.5.3.16 0.0006895 50.0
HKD1_k127_2796513_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 417.0
HKD1_k127_2796513_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 376.0
HKD1_k127_2796513_6 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 380.0
HKD1_k127_2796513_7 ATP hydrolysis coupled proton transport K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 344.0
HKD1_k127_2796513_8 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 347.0
HKD1_k127_2796513_9 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 324.0
HKD1_k127_2837180_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.141e-198 649.0
HKD1_k127_2837180_1 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 447.0
HKD1_k127_2837180_10 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00000000000000000000000521 115.0
HKD1_k127_2837180_11 DivIVA protein K04074 - - 0.0000000000000000634 87.0
HKD1_k127_2837180_12 C4-type zinc ribbon domain K07164 - - 0.0000000000000002912 88.0
HKD1_k127_2837180_13 Helix-hairpin-helix motif K02237 - - 0.0000000000000003854 85.0
HKD1_k127_2837180_14 YGGT family K02221 - - 0.0000000000000005607 89.0
HKD1_k127_2837180_15 Type II transport protein GspH K08084 - - 0.00001464 57.0
HKD1_k127_2837180_2 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 365.0
HKD1_k127_2837180_3 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000062 234.0
HKD1_k127_2837180_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000972 213.0
HKD1_k127_2837180_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000003611 159.0
HKD1_k127_2837180_6 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000227 154.0
HKD1_k127_2837180_7 Yqey-like protein K09117 - - 0.0000000000000000000000000000001887 128.0
HKD1_k127_2837180_8 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000003446 125.0
HKD1_k127_2837180_9 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000000004333 138.0
HKD1_k127_3021109_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 308.0
HKD1_k127_3021109_1 Carbohydrate family 9 binding domain-like - - - 0.000000000000008128 81.0
HKD1_k127_3026570_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 518.0
HKD1_k127_3026570_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 404.0
HKD1_k127_3026570_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 326.0
HKD1_k127_3026570_3 PAP2 superfamily - - - 0.000000000000000000000000000000000000000003969 168.0
HKD1_k127_3026570_4 NmrA-like family - - - 0.000000000000000000000000000000000000008717 163.0
HKD1_k127_302924_0 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 448.0
HKD1_k127_302924_1 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 381.0
HKD1_k127_3052330_0 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 621.0
HKD1_k127_3052330_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 496.0
HKD1_k127_3052330_2 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 312.0
HKD1_k127_3052330_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000375 157.0
HKD1_k127_3059227_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.535e-293 927.0
HKD1_k127_3059227_1 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 607.0
HKD1_k127_3059227_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000008849 228.0
HKD1_k127_3059227_11 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000004092 171.0
HKD1_k127_3059227_12 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000008763 153.0
HKD1_k127_3059227_13 Tetratricopeptide repeat - - - 0.00000000000000000000000001298 120.0
HKD1_k127_3059227_14 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000001849 127.0
HKD1_k127_3059227_15 TIGRFAM TonB K03832 - - 0.00000000000000000000000007491 116.0
HKD1_k127_3059227_16 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000008015 106.0
HKD1_k127_3059227_17 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000001479 98.0
HKD1_k127_3059227_18 Glutathione peroxidase - - - 0.0000000000000000004882 102.0
HKD1_k127_3059227_19 oxidoreductase activity - - - 0.0000000000000000009119 101.0
HKD1_k127_3059227_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 538.0
HKD1_k127_3059227_20 ATPase or kinase K06925 - - 0.00000000000000000205 100.0
HKD1_k127_3059227_21 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000006358 73.0
HKD1_k127_3059227_22 multi-organism process K03195 - - 0.00000008112 64.0
HKD1_k127_3059227_24 Belongs to the ompA family K03286 - - 0.0002404 51.0
HKD1_k127_3059227_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 307.0
HKD1_k127_3059227_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 324.0
HKD1_k127_3059227_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 328.0
HKD1_k127_3059227_6 Riboflavin biosynthesis protein RibD K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 307.0
HKD1_k127_3059227_7 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001338 263.0
HKD1_k127_3059227_8 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000003237 264.0
HKD1_k127_3059227_9 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000002647 219.0
HKD1_k127_3066387_0 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000006989 212.0
HKD1_k127_3066387_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000004959 128.0
HKD1_k127_3066387_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00172,K00441,K03522 - 1.12.98.1,1.2.7.1 0.000000000000000000000001973 109.0
HKD1_k127_3066387_3 deoxyhypusine monooxygenase activity - - - 0.000000007373 68.0
HKD1_k127_3086504_0 4Fe-4S single cluster domain K06937 - - 4.762e-228 718.0
HKD1_k127_3086504_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000007828 135.0
HKD1_k127_3102107_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.875e-287 906.0
HKD1_k127_3102107_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.127e-250 784.0
HKD1_k127_3102107_10 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 349.0
HKD1_k127_3102107_11 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 360.0
HKD1_k127_3102107_12 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 347.0
HKD1_k127_3102107_13 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 323.0
HKD1_k127_3102107_14 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005787 303.0
HKD1_k127_3102107_15 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004871 281.0
HKD1_k127_3102107_16 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000003484 286.0
HKD1_k127_3102107_17 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001167 255.0
HKD1_k127_3102107_18 Competence protein ComEC K02238 - - 0.000000000000000000000000000000000000000000000000000000002386 226.0
HKD1_k127_3102107_19 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001521 215.0
HKD1_k127_3102107_2 adenylosuccinate lyase K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 515.0
HKD1_k127_3102107_20 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000001122 203.0
HKD1_k127_3102107_21 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000003205 211.0
HKD1_k127_3102107_22 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000009868 190.0
HKD1_k127_3102107_23 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000006936 175.0
HKD1_k127_3102107_24 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.0000000000000000000000000000000000000008086 158.0
HKD1_k127_3102107_25 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000000000008877 148.0
HKD1_k127_3102107_26 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000008697 150.0
HKD1_k127_3102107_27 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000007164 144.0
HKD1_k127_3102107_28 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000002592 118.0
HKD1_k127_3102107_29 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000001075 104.0
HKD1_k127_3102107_3 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 463.0
HKD1_k127_3102107_30 Acetyl propionyl-CoA carboxylase alpha subunit K01968,K13777 - 6.4.1.4,6.4.1.5 0.000000000000000001775 93.0
HKD1_k127_3102107_31 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000186 93.0
HKD1_k127_3102107_32 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000657 81.0
HKD1_k127_3102107_33 outer membrane autotransporter barrel domain protein - - - 0.000000000001403 76.0
HKD1_k127_3102107_34 Glutaredoxin-like domain (DUF836) - - - 0.0000001204 63.0
HKD1_k127_3102107_36 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000001573 61.0
HKD1_k127_3102107_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 415.0
HKD1_k127_3102107_5 Aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 396.0
HKD1_k127_3102107_6 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 361.0
HKD1_k127_3102107_7 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 359.0
HKD1_k127_3102107_8 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 349.0
HKD1_k127_3102107_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 350.0
HKD1_k127_3102395_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 467.0
HKD1_k127_3102395_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001832 280.0
HKD1_k127_3102395_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000003435 163.0
HKD1_k127_3112020_0 Oligoendopeptidase f - - - 8.656e-251 792.0
HKD1_k127_3112020_1 ERAP1-like C-terminal domain K01263 - 3.4.11.14 4.828e-244 782.0
HKD1_k127_3112020_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 616.0
HKD1_k127_3112020_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000596 288.0
HKD1_k127_3112020_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000001609 139.0
HKD1_k127_3112020_5 Protein of unknown function (DUF962) - - - 0.00000000000000000005877 89.0
HKD1_k127_3129752_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 2.607e-265 834.0
HKD1_k127_3129752_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000009517 258.0
HKD1_k127_3129752_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000001517 228.0
HKD1_k127_3143531_0 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 543.0
HKD1_k127_3143531_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 485.0
HKD1_k127_3143531_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001851 236.0
HKD1_k127_3143531_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000006855 222.0
HKD1_k127_3147261_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 516.0
HKD1_k127_3147261_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 452.0
HKD1_k127_3147261_2 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 382.0
HKD1_k127_3147261_3 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000004069 197.0
HKD1_k127_3147261_4 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000001855 166.0
HKD1_k127_3147261_5 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000001025 161.0
HKD1_k127_3147261_6 COGs COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease K13735,K20276,K20755,K21449 - 3.4.21.121 0.0000000000000000000000000004789 132.0
HKD1_k127_3147261_7 - - - - 0.00000000000000000000001044 118.0
HKD1_k127_3147261_8 - - - - 0.000000000000000000646 101.0
HKD1_k127_3159349_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 594.0
HKD1_k127_3159349_1 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 466.0
HKD1_k127_3159349_2 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 295.0
HKD1_k127_3159349_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.00000000000000000000000000000003255 136.0
HKD1_k127_3159349_4 methylamine metabolic process - - - 0.000000000000000000000000000003836 128.0
HKD1_k127_3159349_5 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000001946 121.0
HKD1_k127_3159349_6 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000002088 124.0
HKD1_k127_3159349_7 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000002838 104.0
HKD1_k127_3168485_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 605.0
HKD1_k127_3168485_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 428.0
HKD1_k127_3171100_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.171e-231 724.0
HKD1_k127_3171100_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.213e-230 724.0
HKD1_k127_3171100_11 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000002014 134.0
HKD1_k127_3171100_12 Universal stress protein family - - - 0.000000000000000000000000000000009319 131.0
HKD1_k127_3171100_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000001844 110.0
HKD1_k127_3171100_14 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000001363 105.0
HKD1_k127_3171100_15 Polymer-forming cytoskeletal - - - 0.0000000000000000000002983 102.0
HKD1_k127_3171100_16 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000003405 94.0
HKD1_k127_3171100_17 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000000000069 88.0
HKD1_k127_3171100_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000129 75.0
HKD1_k127_3171100_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000262 72.0
HKD1_k127_3171100_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 621.0
HKD1_k127_3171100_20 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0002504 53.0
HKD1_k127_3171100_21 ATP synthase B/B' CF(0) K02109 - - 0.0008269 51.0
HKD1_k127_3171100_3 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 528.0
HKD1_k127_3171100_4 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
HKD1_k127_3171100_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 305.0
HKD1_k127_3171100_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 323.0
HKD1_k127_3171100_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000005394 259.0
HKD1_k127_3171100_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003489 264.0
HKD1_k127_3171100_9 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000001604 227.0
HKD1_k127_31751_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 503.0
HKD1_k127_31751_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 366.0
HKD1_k127_31751_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 305.0
HKD1_k127_31751_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 296.0
HKD1_k127_31751_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000343 261.0
HKD1_k127_31751_5 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001286 229.0
HKD1_k127_31751_6 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000006808 130.0
HKD1_k127_31751_7 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000001003 118.0
HKD1_k127_31751_8 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000001793 96.0
HKD1_k127_31751_9 META domain - - - 0.0000001172 63.0
HKD1_k127_3189517_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 519.0
HKD1_k127_3189517_1 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 421.0
HKD1_k127_3189517_10 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000003197 140.0
HKD1_k127_3189517_11 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.000000000000000000000000000063 136.0
HKD1_k127_3189517_12 - - - - 0.00000000000000000000003048 113.0
HKD1_k127_3189517_13 Helix-turn-helix domain - - - 0.000000000000000002445 100.0
HKD1_k127_3189517_14 - - - - 0.000000000001048 81.0
HKD1_k127_3189517_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000382 71.0
HKD1_k127_3189517_2 ATP-dependent helicase activity K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 396.0
HKD1_k127_3189517_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 295.0
HKD1_k127_3189517_4 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000005322 253.0
HKD1_k127_3189517_5 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000003777 231.0
HKD1_k127_3189517_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000009343 230.0
HKD1_k127_3189517_7 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000001098 218.0
HKD1_k127_3189517_8 Shikimate dehydrogenase substrate binding domain K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000008837 181.0
HKD1_k127_3189517_9 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000001084 164.0
HKD1_k127_32096_0 Involved in galactofuranosyl biosynthesis converts UDO-GlcP to UDP-GalP catalytic activity UDP- glucopyranose UDP-galactopyranose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 496.0
HKD1_k127_32096_1 UDP binding domain K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 428.0
HKD1_k127_32096_2 phosphoribosylformylglycinamidine cyclo-ligase activity K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 357.0
HKD1_k127_32096_3 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000006096 240.0
HKD1_k127_32096_4 Formyl transferase K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000204 224.0
HKD1_k127_32096_6 Psort location CytoplasmicMembrane, score - - - 0.0000003675 63.0
HKD1_k127_32096_7 - - - - 0.0000003779 53.0
HKD1_k127_32096_8 Psort location CytoplasmicMembrane, score - - - 0.000001295 63.0
HKD1_k127_32096_9 glycosyl transferase family - - - 0.000005344 60.0
HKD1_k127_3211392_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 454.0
HKD1_k127_3211392_1 - - - - 0.0000000000000001891 91.0
HKD1_k127_3222853_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 384.0
HKD1_k127_3222853_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 308.0
HKD1_k127_322313_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 400.0
HKD1_k127_322313_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009593 291.0
HKD1_k127_322313_10 Bacterial membrane protein YfhO - - - 0.00000000000000006569 96.0
HKD1_k127_322313_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001993 68.0
HKD1_k127_322313_12 positive regulation of growth rate - - - 0.0000000006626 70.0
HKD1_k127_322313_13 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0008692 46.0
HKD1_k127_322313_2 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000001255 230.0
HKD1_k127_322313_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000003246 210.0
HKD1_k127_322313_4 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000006511 161.0
HKD1_k127_322313_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000002141 139.0
HKD1_k127_322313_6 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000001528 134.0
HKD1_k127_322313_7 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000006365 124.0
HKD1_k127_322313_8 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000002569 109.0
HKD1_k127_322313_9 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000003871 93.0
HKD1_k127_3225464_0 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000002615 265.0
HKD1_k127_3225464_1 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
HKD1_k127_3225464_2 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.00000000000000000000000000000000000000000002739 187.0
HKD1_k127_3225464_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000003378 181.0
HKD1_k127_3225464_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000008496 183.0
HKD1_k127_3225464_5 arylsulfatase A - - - 0.00000000000000000000000000000000000000122 170.0
HKD1_k127_3225464_6 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000002069 158.0
HKD1_k127_3225464_7 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000005274 141.0
HKD1_k127_3225464_8 serine-type endopeptidase activity K20276 - - 0.000000000000000000000000000108 132.0
HKD1_k127_3233008_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 9.873e-223 721.0
HKD1_k127_3233008_1 MacB-like periplasmic core domain - - - 1.758e-194 636.0
HKD1_k127_3233008_10 DinB family - - - 0.00000000000000000000000000000000000000000000000001147 185.0
HKD1_k127_3233008_11 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000002021 156.0
HKD1_k127_3233008_12 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000003218 155.0
HKD1_k127_3233008_13 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000002789 140.0
HKD1_k127_3233008_14 ACT domain - - - 0.000000000000000000000000000002783 132.0
HKD1_k127_3233008_2 Response regulator receiver - - - 5.143e-194 621.0
HKD1_k127_3233008_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 616.0
HKD1_k127_3233008_4 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 509.0
HKD1_k127_3233008_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 501.0
HKD1_k127_3233008_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 434.0
HKD1_k127_3233008_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 352.0
HKD1_k127_3233008_8 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 336.0
HKD1_k127_3233008_9 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000001495 202.0
HKD1_k127_3246297_0 lysine biosynthetic process via aminoadipic acid - - - 7.867e-220 709.0
HKD1_k127_3246297_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 332.0
HKD1_k127_3246297_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003077 272.0
HKD1_k127_3246297_3 phosphorelay signal transduction system - - - 0.000000000000000000000002423 111.0
HKD1_k127_3246297_4 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000001394 100.0
HKD1_k127_3246297_5 - - - - 0.0001682 46.0
HKD1_k127_32463_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003549 280.0
HKD1_k127_32463_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000001828 248.0
HKD1_k127_32463_10 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000005292 87.0
HKD1_k127_32463_11 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.0003803 51.0
HKD1_k127_32463_2 polysaccharide deactylase family protein - - - 0.0000000000000000000000000000000000000000000000003002 188.0
HKD1_k127_32463_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000005606 177.0
HKD1_k127_32463_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000002493 185.0
HKD1_k127_32463_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000004298 159.0
HKD1_k127_32463_6 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000001167 149.0
HKD1_k127_32463_7 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000002355 117.0
HKD1_k127_32463_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000005537 103.0
HKD1_k127_32463_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000001826 98.0
HKD1_k127_3254130_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000009812 165.0
HKD1_k127_3254130_1 TonB-dependent receptor plug - - - 0.00000000000000000000008932 115.0
HKD1_k127_3254130_2 TonB dependent receptor K02014,K16092 - - 0.000000000000001137 91.0
HKD1_k127_3280783_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1688.0
HKD1_k127_3280783_1 Cytochrome c - - - 5.748e-201 634.0
HKD1_k127_3280783_2 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 619.0
HKD1_k127_3280783_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000228 220.0
HKD1_k127_3280783_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000001519 190.0
HKD1_k127_3280783_5 Protein of unknown function (DUF2945) - - - 0.00000000000000000000000000000001117 133.0
HKD1_k127_3280783_7 helix_turn_helix, mercury resistance K19591 - - 0.000000000006092 72.0
HKD1_k127_3315985_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008188 293.0
HKD1_k127_3315985_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004731 268.0
HKD1_k127_3315985_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000001337 176.0
HKD1_k127_3315985_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000000002264 149.0
HKD1_k127_3315985_4 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.00000000000000000000000000000000003135 144.0
HKD1_k127_3315985_5 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.000000000000000000000000000000002449 142.0
HKD1_k127_3315985_7 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000007194 65.0
HKD1_k127_3317394_0 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 410.0
HKD1_k127_3317394_1 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 394.0
HKD1_k127_3317394_2 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 372.0
HKD1_k127_3317394_3 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000004299 214.0
HKD1_k127_3317394_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000001016 196.0
HKD1_k127_3317394_5 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000001229 204.0
HKD1_k127_3323432_0 ABC transporter transmembrane region K06147,K18893 - - 1.933e-246 773.0
HKD1_k127_3323432_1 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 477.0
HKD1_k127_3323432_10 SAM-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000004441 179.0
HKD1_k127_3323432_11 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000001289 143.0
HKD1_k127_3323432_12 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000004709 133.0
HKD1_k127_3323432_13 Peptidase family M1 domain - - - 0.0000000000000000009676 101.0
HKD1_k127_3323432_14 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000001809 76.0
HKD1_k127_3323432_2 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 410.0
HKD1_k127_3323432_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 314.0
HKD1_k127_3323432_4 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004543 276.0
HKD1_k127_3323432_5 PFAM peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004867 251.0
HKD1_k127_3323432_6 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004455 252.0
HKD1_k127_3323432_7 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000002751 223.0
HKD1_k127_3323432_9 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000009024 205.0
HKD1_k127_3372623_0 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 569.0
HKD1_k127_3372623_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 329.0
HKD1_k127_3372623_2 Peptidase M56 - - - 0.00000000000001475 86.0
HKD1_k127_3391982_0 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000002041 218.0
HKD1_k127_3391982_1 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000008111 183.0
HKD1_k127_3391982_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000001255 183.0
HKD1_k127_3391982_3 COG4942 Membrane-bound metallopeptidase - - - 0.0000000000000000000001447 99.0
HKD1_k127_3397711_0 Dehydrogenase E1 component K00162,K11381 - 1.2.4.1,1.2.4.4 6.174e-274 886.0
HKD1_k127_3397711_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.773e-273 852.0
HKD1_k127_3397711_10 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 404.0
HKD1_k127_3397711_11 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 347.0
HKD1_k127_3397711_12 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000002928 205.0
HKD1_k127_3397711_13 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000005706 192.0
HKD1_k127_3397711_14 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000000001182 167.0
HKD1_k127_3397711_15 - - - - 0.0000000000000000000000000000000001949 134.0
HKD1_k127_3397711_16 hyperosmotic response - - - 0.0000000000000000000000000008457 118.0
HKD1_k127_3397711_17 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000961 114.0
HKD1_k127_3397711_18 PFAM CBS domain containing protein - - - 0.000000000000000000000059 105.0
HKD1_k127_3397711_19 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000002208 98.0
HKD1_k127_3397711_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.803e-236 741.0
HKD1_k127_3397711_20 - - - - 0.00000000000000000136 90.0
HKD1_k127_3397711_21 - - - - 0.00000000000000003413 95.0
HKD1_k127_3397711_22 Thiamine-binding protein - - - 0.000000000000000808 90.0
HKD1_k127_3397711_23 Phosphopantetheine attachment site - - - 0.000000000000005419 88.0
HKD1_k127_3397711_24 - - - - 0.0000000001383 72.0
HKD1_k127_3397711_3 DNA polymerase beta thumb K02347 - - 1.016e-229 757.0
HKD1_k127_3397711_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 604.0
HKD1_k127_3397711_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 465.0
HKD1_k127_3397711_6 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 459.0
HKD1_k127_3397711_7 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 453.0
HKD1_k127_3397711_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 415.0
HKD1_k127_3397711_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 410.0
HKD1_k127_3473248_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 576.0
HKD1_k127_3473248_1 - - - - 0.00000000000000001902 96.0
HKD1_k127_3491530_0 PFAM Amidase - - - 1.433e-272 850.0
HKD1_k127_3491530_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 560.0
HKD1_k127_3491530_10 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000007656 119.0
HKD1_k127_3491530_11 AsmA family K07289,K07290 - - 0.000000001572 71.0
HKD1_k127_3491530_12 Serine threonine-protein kinase - - - 0.0000328 57.0
HKD1_k127_3491530_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 356.0
HKD1_k127_3491530_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 291.0
HKD1_k127_3491530_4 Belongs to the FPG family K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000009465 241.0
HKD1_k127_3491530_5 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006966 226.0
HKD1_k127_3491530_6 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000004899 228.0
HKD1_k127_3491530_7 DinB family - - - 0.0000000000000000000000000000000000005005 146.0
HKD1_k127_3491530_8 FOG TPR repeat SEL1 subfamily K07126 - - 0.00000000000000000000000000000000003109 155.0
HKD1_k127_3491530_9 chain release factor K15034 - - 0.000000000000000000000000000002009 134.0
HKD1_k127_3500683_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.958e-244 779.0
HKD1_k127_3500683_1 Peptidase family M13 K07386 - - 8.58e-214 683.0
HKD1_k127_3500683_10 Psort location Cytoplasmic, score - - - 0.00000003409 63.0
HKD1_k127_3500683_11 Sigma-70, region 4 K03088 - - 0.0000002489 60.0
HKD1_k127_3500683_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 532.0
HKD1_k127_3500683_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 511.0
HKD1_k127_3500683_4 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 407.0
HKD1_k127_3500683_5 CorA-like Mg2+ transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 395.0
HKD1_k127_3500683_6 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 383.0
HKD1_k127_3500683_7 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 369.0
HKD1_k127_3500683_8 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.000000000000000000000000000002776 135.0
HKD1_k127_3500683_9 Forkhead associated domain - - - 0.000000000000004909 83.0
HKD1_k127_35944_0 protein histidine kinase activity K11959 - - 0.000000000000000000000000000000000001135 151.0
HKD1_k127_3598601_0 WD40-like Beta Propeller Repeat - - - 5.695e-194 627.0
HKD1_k127_3684133_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 309.0
HKD1_k127_3684133_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006929 257.0
HKD1_k127_3684133_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000001273 244.0
HKD1_k127_3699456_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 1.575e-281 902.0
HKD1_k127_3699456_1 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.723e-213 675.0
HKD1_k127_3699456_10 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000002469 218.0
HKD1_k127_3699456_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000006523 160.0
HKD1_k127_3699456_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000002452 167.0
HKD1_k127_3699456_13 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.000000000000000000000000000000000008089 142.0
HKD1_k127_3699456_14 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000005529 141.0
HKD1_k127_3699456_15 domain, Protein - - - 0.00000000000000000000000002275 126.0
HKD1_k127_3699456_16 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000001032 110.0
HKD1_k127_3699456_17 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000001194 105.0
HKD1_k127_3699456_18 - - - - 0.00000000000000000000125 106.0
HKD1_k127_3699456_19 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000002292 82.0
HKD1_k127_3699456_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 477.0
HKD1_k127_3699456_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 432.0
HKD1_k127_3699456_4 Pfam:Arch_ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 287.0
HKD1_k127_3699456_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007812 284.0
HKD1_k127_3699456_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004557 278.0
HKD1_k127_3699456_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 270.0
HKD1_k127_3699456_8 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000005435 247.0
HKD1_k127_3699456_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000001501 218.0
HKD1_k127_3709420_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.028e-287 895.0
HKD1_k127_3709420_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 5.089e-231 728.0
HKD1_k127_3709420_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 368.0
HKD1_k127_3709420_3 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000008904 254.0
HKD1_k127_3709420_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000002126 180.0
HKD1_k127_3709420_5 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000001467 106.0
HKD1_k127_373850_0 Involved in the tonB-independent uptake of proteins - - - 5.01e-227 732.0
HKD1_k127_373850_1 Involved in the tonB-independent uptake of proteins - - - 2.181e-198 639.0
HKD1_k127_373850_10 Doxx family K15977 - - 0.0000000000000000000000000000001122 137.0
HKD1_k127_373850_11 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.0000000000000000000000008135 116.0
HKD1_k127_373850_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 574.0
HKD1_k127_373850_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 410.0
HKD1_k127_373850_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 367.0
HKD1_k127_373850_5 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 298.0
HKD1_k127_373850_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000692 268.0
HKD1_k127_373850_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000493 261.0
HKD1_k127_373850_8 chlorophyll binding K03286,K03640 - - 0.000000000000000000000000000000000000000000000000000000007739 211.0
HKD1_k127_373850_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000001545 180.0
HKD1_k127_374253_0 Flavin containing amine oxidoreductase - - - 2.066e-286 888.0
HKD1_k127_374253_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 561.0
HKD1_k127_374253_2 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 464.0
HKD1_k127_374253_3 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 465.0
HKD1_k127_374253_4 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000002824 238.0
HKD1_k127_3765535_0 Involved in the tonB-independent uptake of proteins - - - 2.715e-207 672.0
HKD1_k127_3765535_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 437.0
HKD1_k127_3765535_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000411 72.0
HKD1_k127_3765567_0 Involved in the tonB-independent uptake of proteins - - - 2.78e-202 659.0
HKD1_k127_3765567_1 to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000002885 92.0
HKD1_k127_3765567_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000002182 73.0
HKD1_k127_377914_0 Involved in the tonB-independent uptake of proteins - - - 1.332e-206 696.0
HKD1_k127_377914_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 631.0
HKD1_k127_377914_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000002106 174.0
HKD1_k127_377914_11 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000001865 96.0
HKD1_k127_377914_12 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000006611 76.0
HKD1_k127_377914_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 522.0
HKD1_k127_377914_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 410.0
HKD1_k127_377914_4 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 364.0
HKD1_k127_377914_5 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 360.0
HKD1_k127_377914_6 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002596 280.0
HKD1_k127_377914_7 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000006848 244.0
HKD1_k127_377914_8 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000006617 236.0
HKD1_k127_377914_9 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000009577 222.0
HKD1_k127_378809_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 536.0
HKD1_k127_378809_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 498.0
HKD1_k127_378809_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
HKD1_k127_378809_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009899 275.0
HKD1_k127_378809_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006366 282.0
HKD1_k127_378809_5 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000001175 82.0
HKD1_k127_3818252_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 586.0
HKD1_k127_3818252_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000003594 237.0
HKD1_k127_3818252_2 CGNR zinc finger - - - 0.000000000000000000000000005167 121.0
HKD1_k127_3818252_3 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000002723 111.0
HKD1_k127_3818252_4 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000004096 117.0
HKD1_k127_3823517_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01539 - 3.6.3.9 0.0 1057.0
HKD1_k127_3823517_1 ErfK YbiS YcfS YnhG family protein K21470 - - 8.072e-214 680.0
HKD1_k127_3823517_10 - - - - 0.0001185 49.0
HKD1_k127_3823517_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001326 241.0
HKD1_k127_3823517_3 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001811 233.0
HKD1_k127_3823517_4 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
HKD1_k127_3823517_5 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000004249 125.0
HKD1_k127_3823517_7 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000002893 112.0
HKD1_k127_3823517_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000009327 55.0
HKD1_k127_3844266_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1360.0
HKD1_k127_3844266_1 Belongs to the glycosyl hydrolase 57 family - - - 1.457e-312 979.0
HKD1_k127_3844266_10 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000002247 246.0
HKD1_k127_3844266_11 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004334 246.0
HKD1_k127_3844266_12 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000006833 200.0
HKD1_k127_3844266_13 MobA-Related Protein K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000001877 173.0
HKD1_k127_3844266_14 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000121 156.0
HKD1_k127_3844266_15 - - - - 0.00000000000000000000000000000000000003202 165.0
HKD1_k127_3844266_16 XdhC and CoxI family - - - 0.00000000000000000005004 92.0
HKD1_k127_3844266_17 peptidyl-tyrosine sulfation - - - 0.0000008088 63.0
HKD1_k127_3844266_18 Protein tyrosine kinase K12132 - 2.7.11.1 0.000005593 60.0
HKD1_k127_3844266_19 - - - - 0.00005656 55.0
HKD1_k127_3844266_2 helicase activity - - - 1.576e-309 967.0
HKD1_k127_3844266_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.125e-304 947.0
HKD1_k127_3844266_4 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 467.0
HKD1_k127_3844266_5 Mandelate racemase muconate lactonizing enzyme K02549,K19802 - 4.2.1.113,5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008962 424.0
HKD1_k127_3844266_6 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 366.0
HKD1_k127_3844266_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 333.0
HKD1_k127_3844266_8 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 325.0
HKD1_k127_3844266_9 metallochaperone-like domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006385 280.0
HKD1_k127_3906611_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 1.168e-287 904.0
HKD1_k127_3906611_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 532.0
HKD1_k127_3906611_10 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000003695 167.0
HKD1_k127_3906611_11 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000001535 145.0
HKD1_k127_3906611_12 endo-1,4-beta-xylanase activity - GO:0005575,GO:0005576 - 0.00000000000000000000003202 113.0
HKD1_k127_3906611_13 Domain of unknown function (DUF4439) - - - 0.000000000000000000003012 106.0
HKD1_k127_3906611_14 Anti-sigma-K factor rskA - - - 0.00000000000000000002356 100.0
HKD1_k127_3906611_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 472.0
HKD1_k127_3906611_3 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 477.0
HKD1_k127_3906611_4 PFAM Na-Ca exchanger integrin-beta4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 420.0
HKD1_k127_3906611_5 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 323.0
HKD1_k127_3906611_6 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001614 284.0
HKD1_k127_3906611_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
HKD1_k127_3906611_8 HemY domain protein - - - 0.00000000000000000000000000000000000000003708 177.0
HKD1_k127_3906611_9 Peptidase family M23 - - - 0.0000000000000000000000000000000000000003918 160.0
HKD1_k127_3931253_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 393.0
HKD1_k127_3931253_1 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000004708 208.0
HKD1_k127_3931253_2 YCII-related domain - - - 0.00000000000000000003759 95.0
HKD1_k127_3931253_3 E-Z type HEAT repeats - - - 0.000001112 61.0
HKD1_k127_4018444_0 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 340.0
HKD1_k127_4018444_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000002676 196.0
HKD1_k127_4018444_2 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000002793 142.0
HKD1_k127_4018444_4 - - - - 0.000000000000001995 87.0
HKD1_k127_4022433_0 MacB-like periplasmic core domain - - - 3.566e-320 1005.0
HKD1_k127_4022433_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.837e-242 760.0
HKD1_k127_4022433_10 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 448.0
HKD1_k127_4022433_11 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 436.0
HKD1_k127_4022433_12 Belongs to the OprB family K16080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 409.0
HKD1_k127_4022433_13 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 405.0
HKD1_k127_4022433_14 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 404.0
HKD1_k127_4022433_15 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 391.0
HKD1_k127_4022433_16 peptidase M24 K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 374.0
HKD1_k127_4022433_17 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 320.0
HKD1_k127_4022433_18 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 291.0
HKD1_k127_4022433_19 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001658 290.0
HKD1_k127_4022433_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.178e-220 693.0
HKD1_k127_4022433_20 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003985 304.0
HKD1_k127_4022433_21 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000431 276.0
HKD1_k127_4022433_22 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007076 278.0
HKD1_k127_4022433_23 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000142 280.0
HKD1_k127_4022433_24 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 258.0
HKD1_k127_4022433_25 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 264.0
HKD1_k127_4022433_26 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002345 246.0
HKD1_k127_4022433_27 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001686 257.0
HKD1_k127_4022433_28 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000001551 233.0
HKD1_k127_4022433_29 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002136 224.0
HKD1_k127_4022433_3 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 5.351e-213 685.0
HKD1_k127_4022433_30 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000001451 220.0
HKD1_k127_4022433_31 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000001487 211.0
HKD1_k127_4022433_32 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000004863 193.0
HKD1_k127_4022433_33 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000002428 192.0
HKD1_k127_4022433_34 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000003163 198.0
HKD1_k127_4022433_35 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000006793 178.0
HKD1_k127_4022433_36 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000003036 189.0
HKD1_k127_4022433_37 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000001779 184.0
HKD1_k127_4022433_38 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000007681 166.0
HKD1_k127_4022433_39 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000000000000000000000000000008221 144.0
HKD1_k127_4022433_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 582.0
HKD1_k127_4022433_40 Helix-hairpin-helix motif - - - 0.000000000000000000000000000000005639 139.0
HKD1_k127_4022433_41 Methyltransferase domain - - - 0.00000000000000000000000000000005095 141.0
HKD1_k127_4022433_42 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000003309 125.0
HKD1_k127_4022433_43 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000004706 104.0
HKD1_k127_4022433_44 Cytochrome c - - - 0.00000000000000000002547 98.0
HKD1_k127_4022433_45 PFAM FecR protein - - - 0.0000000000000000001168 103.0
HKD1_k127_4022433_46 peptidyl-tyrosine sulfation - - - 0.00000000000000005063 98.0
HKD1_k127_4022433_47 fatty acid desaturase - - - 0.000000000000001158 89.0
HKD1_k127_4022433_48 Universal stress protein K06149 - - 0.00000000000000446 88.0
HKD1_k127_4022433_49 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000006362 89.0
HKD1_k127_4022433_5 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 570.0
HKD1_k127_4022433_52 metallopeptidase activity - - - 0.00000000000006645 83.0
HKD1_k127_4022433_53 PFAM secretion protein HlyD family protein K01993 - - 0.000000000002133 80.0
HKD1_k127_4022433_54 peptidyl-tyrosine sulfation - - - 0.000000000004215 73.0
HKD1_k127_4022433_55 DNA-templated transcription, termination K02600,K02945 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000001131 75.0
HKD1_k127_4022433_57 Helix-hairpin-helix motif - - - 0.00000001037 66.0
HKD1_k127_4022433_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 550.0
HKD1_k127_4022433_60 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00001182 53.0
HKD1_k127_4022433_62 PFAM blue (type 1) copper domain protein - - - 0.0005583 51.0
HKD1_k127_4022433_63 - - - - 0.0007967 51.0
HKD1_k127_4022433_7 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 529.0
HKD1_k127_4022433_8 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 520.0
HKD1_k127_4022433_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 439.0
HKD1_k127_4022789_0 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 341.0
HKD1_k127_4022789_1 - - - - 0.0000000000000000000000000000000000000000000000002213 183.0
HKD1_k127_4022789_2 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000006464 128.0
HKD1_k127_4022789_3 Aromatic acid exporter family member 1 - - - 0.00000000000004185 83.0
HKD1_k127_4069920_0 heat shock protein binding - - - 4.737e-195 669.0
HKD1_k127_4069920_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 5.808e-194 617.0
HKD1_k127_4069920_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000004346 129.0
HKD1_k127_4069920_11 - - - - 0.0000000000000000004217 97.0
HKD1_k127_4069920_12 Protein of unknown function (DUF962) - - - 0.000000000006993 78.0
HKD1_k127_4069920_13 Iron-sulphur cluster biosynthesis K13628 - - 0.0001752 49.0
HKD1_k127_4069920_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 558.0
HKD1_k127_4069920_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 516.0
HKD1_k127_4069920_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 380.0
HKD1_k127_4069920_5 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 362.0
HKD1_k127_4069920_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000001478 217.0
HKD1_k127_4069920_7 Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 - - - 0.0000000000000000000000000000000000000000000000000000002322 213.0
HKD1_k127_4069920_8 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000002346 156.0
HKD1_k127_4069920_9 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000001327 140.0
HKD1_k127_407354_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 502.0
HKD1_k127_407354_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 461.0
HKD1_k127_407354_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 422.0
HKD1_k127_407354_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 391.0
HKD1_k127_407354_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000003633 178.0
HKD1_k127_407354_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000003638 153.0
HKD1_k127_407354_6 Thioesterase superfamily K10806 - - 0.000000000000000000000000000001703 134.0
HKD1_k127_4115903_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 643.0
HKD1_k127_4115903_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 505.0
HKD1_k127_4115903_2 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000008902 169.0
HKD1_k127_4118181_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 374.0
HKD1_k127_4118181_1 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000001242 223.0
HKD1_k127_4118181_2 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000009543 174.0
HKD1_k127_4118181_3 - - - - 0.000000000000000000000000000000006321 135.0
HKD1_k127_4118181_4 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000002609 111.0
HKD1_k127_4121612_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 345.0
HKD1_k127_4121612_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005005 267.0
HKD1_k127_4130921_0 Involved in the tonB-independent uptake of proteins - - - 1.049e-212 719.0
HKD1_k127_4130921_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 411.0
HKD1_k127_4130921_2 PFAM monooxygenase FAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 302.0
HKD1_k127_4130921_3 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001602 305.0
HKD1_k127_4130921_4 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000007661 195.0
HKD1_k127_4130921_5 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000005574 139.0
HKD1_k127_4130921_6 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000008414 155.0
HKD1_k127_4130921_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000008793 145.0
HKD1_k127_4130921_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000001097 79.0
HKD1_k127_415038_0 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 359.0
HKD1_k127_415038_1 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 354.0
HKD1_k127_415038_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 339.0
HKD1_k127_415038_3 alcohol dehydrogenase K18012 - 1.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 313.0
HKD1_k127_415038_4 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 310.0
HKD1_k127_415038_5 - - - - 0.00000003182 66.0
HKD1_k127_4170327_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 562.0
HKD1_k127_4170327_1 FAD binding domain K00486 - 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 460.0
HKD1_k127_4170327_2 methyltransferase K09846 - 2.1.1.210 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 442.0
HKD1_k127_4170327_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 368.0
HKD1_k127_4170327_4 - - - - 0.000000000000000000000000000000000000000000000007587 197.0
HKD1_k127_4170327_5 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000000000000008967 155.0
HKD1_k127_4170327_6 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000001798 117.0
HKD1_k127_4170327_7 - - - - 0.000006434 55.0
HKD1_k127_4171425_0 Involved in the tonB-independent uptake of proteins - - - 2.149e-235 755.0
HKD1_k127_4171425_1 Involved in the tonB-independent uptake of proteins - - - 1.681e-201 665.0
HKD1_k127_4171425_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000006478 220.0
HKD1_k127_4171425_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000001505 154.0
HKD1_k127_4171425_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000008432 128.0
HKD1_k127_41798_0 OPT oligopeptide transporter protein - - - 3.75e-232 748.0
HKD1_k127_41798_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 466.0
HKD1_k127_41798_2 - - - - 0.00000000000000000000000000000000007162 147.0
HKD1_k127_41798_3 - - - - 0.000000000000000000000000000003029 128.0
HKD1_k127_41798_4 DoxX K15977 - - 0.0000000000008181 82.0
HKD1_k127_41798_5 D-aminopeptidase K16203 - - 0.00000004088 55.0
HKD1_k127_4184076_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 530.0
HKD1_k127_4184076_1 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000001115 191.0
HKD1_k127_4184076_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000001383 177.0
HKD1_k127_4184076_3 - - - - 0.0000000001359 66.0
HKD1_k127_4203052_0 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000456 248.0
HKD1_k127_4203052_1 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000004118 242.0
HKD1_k127_4203052_2 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000001977 108.0
HKD1_k127_4204699_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 537.0
HKD1_k127_4204699_1 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 422.0
HKD1_k127_4204699_10 Bacterial Ig-like domain (group 3) - - - 0.00000000000000000000000000000000000000000001214 189.0
HKD1_k127_4204699_11 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000002371 165.0
HKD1_k127_4204699_12 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000004285 157.0
HKD1_k127_4204699_13 energy transducer activity K03832 - - 0.00000000000127 81.0
HKD1_k127_4204699_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001365 64.0
HKD1_k127_4204699_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 365.0
HKD1_k127_4204699_3 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
HKD1_k127_4204699_4 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 359.0
HKD1_k127_4204699_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007706 280.0
HKD1_k127_4204699_6 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004401 240.0
HKD1_k127_4204699_7 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000005628 250.0
HKD1_k127_4204699_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000003009 226.0
HKD1_k127_4204699_9 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000004019 191.0
HKD1_k127_4235267_0 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 476.0
HKD1_k127_4235267_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 316.0
HKD1_k127_4235267_10 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000001103 146.0
HKD1_k127_4235267_11 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000002823 129.0
HKD1_k127_4235267_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000136 104.0
HKD1_k127_4235267_13 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000003166 70.0
HKD1_k127_4235267_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009511 298.0
HKD1_k127_4235267_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000002054 229.0
HKD1_k127_4235267_4 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001757 218.0
HKD1_k127_4235267_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000006048 227.0
HKD1_k127_4235267_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000001098 210.0
HKD1_k127_4235267_7 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000007645 184.0
HKD1_k127_4235267_8 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.000000000000000000000000000000000000000004803 173.0
HKD1_k127_4235267_9 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000001168 148.0
HKD1_k127_4258017_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 1.439e-277 879.0
HKD1_k127_4258017_1 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 545.0
HKD1_k127_4258017_10 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000001231 198.0
HKD1_k127_4258017_11 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000005462 169.0
HKD1_k127_4258017_12 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000001253 137.0
HKD1_k127_4258017_13 Thioredoxin-like - - - 0.00000000000000000000000007915 123.0
HKD1_k127_4258017_14 Thioredoxin-like - - - 0.0000000000000000000000001187 114.0
HKD1_k127_4258017_15 protein histidine kinase activity K06375 - - 0.0000000000000000000003536 105.0
HKD1_k127_4258017_16 by modhmm - - - 0.000000000000000989 89.0
HKD1_k127_4258017_19 protein-disulfide reductase activity K04084 - 1.8.1.8 0.0000000000001113 78.0
HKD1_k127_4258017_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 550.0
HKD1_k127_4258017_20 Beta-lactamase - - - 0.0000000002568 74.0
HKD1_k127_4258017_21 - - - - 0.000000005445 68.0
HKD1_k127_4258017_22 Copper binding proteins, plastocyanin/azurin family - - - 0.0000002523 62.0
HKD1_k127_4258017_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 528.0
HKD1_k127_4258017_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 484.0
HKD1_k127_4258017_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001092 286.0
HKD1_k127_4258017_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003751 278.0
HKD1_k127_4258017_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006447 264.0
HKD1_k127_4258017_8 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000008457 233.0
HKD1_k127_4258017_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000005328 213.0
HKD1_k127_4268266_0 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000004472 203.0
HKD1_k127_4268266_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000001435 196.0
HKD1_k127_4268266_2 C-terminal region of aryl-sulfatase - - - 0.00000000000000000000000000000000000000003542 154.0
HKD1_k127_4268266_3 Response regulator receiver domain - - - 0.000000000000000000000005894 109.0
HKD1_k127_4278297_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.928e-287 919.0
HKD1_k127_4278297_1 Belongs to the ClpA ClpB family K03696 - - 4.526e-285 897.0
HKD1_k127_4278297_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
HKD1_k127_4278297_11 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 320.0
HKD1_k127_4278297_12 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 321.0
HKD1_k127_4278297_13 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003774 307.0
HKD1_k127_4278297_14 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006875 309.0
HKD1_k127_4278297_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000006823 274.0
HKD1_k127_4278297_16 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008785 264.0
HKD1_k127_4278297_17 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001449 266.0
HKD1_k127_4278297_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004659 265.0
HKD1_k127_4278297_19 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008329 252.0
HKD1_k127_4278297_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 551.0
HKD1_k127_4278297_20 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004557 251.0
HKD1_k127_4278297_21 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000009806 246.0
HKD1_k127_4278297_22 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000001648 228.0
HKD1_k127_4278297_23 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000713 242.0
HKD1_k127_4278297_24 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000001587 219.0
HKD1_k127_4278297_25 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000002615 207.0
HKD1_k127_4278297_26 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000001071 228.0
HKD1_k127_4278297_27 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000005877 207.0
HKD1_k127_4278297_28 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000005541 187.0
HKD1_k127_4278297_29 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000006897 165.0
HKD1_k127_4278297_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 427.0
HKD1_k127_4278297_30 OmpA family K03640 - - 0.000000000000000000000000000000000000002499 154.0
HKD1_k127_4278297_31 - K07018 - - 0.00000000000000000000000000000000000000264 169.0
HKD1_k127_4278297_32 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000001484 150.0
HKD1_k127_4278297_33 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000016 144.0
HKD1_k127_4278297_34 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000001153 131.0
HKD1_k127_4278297_35 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000542 143.0
HKD1_k127_4278297_36 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000006229 126.0
HKD1_k127_4278297_37 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000007067 132.0
HKD1_k127_4278297_38 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000002911 133.0
HKD1_k127_4278297_39 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000007615 117.0
HKD1_k127_4278297_4 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 418.0
HKD1_k127_4278297_40 Outer membrane lipoprotein - - - 0.000000000000000000000006052 116.0
HKD1_k127_4278297_41 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000001659 111.0
HKD1_k127_4278297_42 Putative Fe-S cluster K00380 - 1.8.1.2 0.00000000000000000038 96.0
HKD1_k127_4278297_43 Belongs to the thioredoxin family K03671 - - 0.00000000000000006889 81.0
HKD1_k127_4278297_44 Lipopolysaccharide-assembly - - - 0.0000000000000001344 95.0
HKD1_k127_4278297_45 PFAM Outer membrane K06142 - - 0.000000000000003241 85.0
HKD1_k127_4278297_46 thiolester hydrolase activity K17362 - - 0.000000000000005477 88.0
HKD1_k127_4278297_47 Ribosomal protein S20 K02968 - - 0.000000000666 63.0
HKD1_k127_4278297_48 TIGRFAM TonB family K03832 - - 0.000000514 60.0
HKD1_k127_4278297_49 PFAM Transglutaminase-like - - - 0.000001378 60.0
HKD1_k127_4278297_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 379.0
HKD1_k127_4278297_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 342.0
HKD1_k127_4278297_7 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 336.0
HKD1_k127_4278297_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 315.0
HKD1_k127_4278297_9 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 315.0
HKD1_k127_4290455_0 Bacterial protein of unknown function (DUF885) - - - 1.656e-214 681.0
HKD1_k127_4290455_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 603.0
HKD1_k127_4290455_10 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000001072 248.0
HKD1_k127_4290455_11 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000000003394 165.0
HKD1_k127_4290455_12 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000002492 89.0
HKD1_k127_4290455_13 Thioredoxin-like - - - 0.0000002655 59.0
HKD1_k127_4290455_14 - - - - 0.000002355 56.0
HKD1_k127_4290455_2 PFAM Aldehyde dehydrogenase K13877 - 1.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 584.0
HKD1_k127_4290455_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 384.0
HKD1_k127_4290455_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 374.0
HKD1_k127_4290455_5 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 368.0
HKD1_k127_4290455_6 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 358.0
HKD1_k127_4290455_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 339.0
HKD1_k127_4290455_8 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 322.0
HKD1_k127_4290455_9 4-hydroxyproline epimerase activity K01777,K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4,5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 334.0
HKD1_k127_4299768_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
HKD1_k127_4299768_1 DinB family - - - 0.000000000000000000000004098 110.0
HKD1_k127_4299768_2 - - - - 0.00000000000000000002014 98.0
HKD1_k127_4299768_3 acetyltransferase - - - 0.000000000000007932 82.0
HKD1_k127_4309966_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 569.0
HKD1_k127_4309966_1 Transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 379.0
HKD1_k127_4309966_2 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003861 269.0
HKD1_k127_4309966_3 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000000000000006947 210.0
HKD1_k127_4340433_0 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 383.0
HKD1_k127_4340433_1 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002396 254.0
HKD1_k127_4340433_10 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000008369 57.0
HKD1_k127_4340433_11 Transcriptional regulator - - - 0.0002392 48.0
HKD1_k127_4340433_2 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
HKD1_k127_4340433_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000004515 192.0
HKD1_k127_4340433_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000001392 147.0
HKD1_k127_4340433_5 DNA methylase K07316 - 2.1.1.72 0.0000000000000000000000000000001188 128.0
HKD1_k127_4340433_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000004361 104.0
HKD1_k127_4340433_7 - - - - 0.00000000000000000000379 96.0
HKD1_k127_4340433_8 Dienelactone hydrolase family - - - 0.0000000000000000005959 87.0
HKD1_k127_4340433_9 Membrane - - - 0.0000000005413 68.0
HKD1_k127_4357302_0 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 468.0
HKD1_k127_4357302_1 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 398.0
HKD1_k127_4357302_2 - - - - 0.00000000000000000000000000000000009524 138.0
HKD1_k127_4357302_3 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.0000000000000000000009378 100.0
HKD1_k127_4357302_4 Family of unknown function (DUF5335) - - - 0.00000000645 68.0
HKD1_k127_4361514_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 542.0
HKD1_k127_4361514_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 549.0
HKD1_k127_4361514_10 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000002128 169.0
HKD1_k127_4361514_11 Evidence 4 Homologs of previously reported genes of - - - 0.000000000002576 74.0
HKD1_k127_4361514_12 Metallo-peptidase family M12 - - - 0.00000000001207 78.0
HKD1_k127_4361514_13 guanyl-nucleotide exchange factor activity K05349 - 3.2.1.21 0.000001015 62.0
HKD1_k127_4361514_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 480.0
HKD1_k127_4361514_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 441.0
HKD1_k127_4361514_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 426.0
HKD1_k127_4361514_5 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003482 307.0
HKD1_k127_4361514_6 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000004833 194.0
HKD1_k127_4361514_7 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000002549 188.0
HKD1_k127_4361514_8 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000001345 181.0
HKD1_k127_4361514_9 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000007361 169.0
HKD1_k127_439634_0 Hydrolase CocE NonD family - - - 3.114e-306 956.0
HKD1_k127_439634_1 enterobactin catabolic process - - - 1.805e-251 796.0
HKD1_k127_439634_10 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000004252 211.0
HKD1_k127_439634_11 - - - - 0.00000000000000000000000000000000000000000000000000003219 211.0
HKD1_k127_439634_12 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000000000000000001166 179.0
HKD1_k127_439634_13 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000001348 171.0
HKD1_k127_439634_14 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000000003959 129.0
HKD1_k127_439634_15 Universal stress protein K06149 - - 0.000000000000001385 83.0
HKD1_k127_439634_16 Bacterial antitoxin of type II TA system, VapB - - - 0.0002396 54.0
HKD1_k127_439634_2 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 511.0
HKD1_k127_439634_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 486.0
HKD1_k127_439634_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 486.0
HKD1_k127_439634_5 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 362.0
HKD1_k127_439634_6 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 368.0
HKD1_k127_439634_7 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 308.0
HKD1_k127_439634_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002281 260.0
HKD1_k127_439634_9 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000003485 231.0
HKD1_k127_4398260_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1374.0
HKD1_k127_4398260_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 442.0
HKD1_k127_4398260_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 326.0
HKD1_k127_4398260_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000001242 194.0
HKD1_k127_4398260_4 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000005266 165.0
HKD1_k127_4398260_5 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000001382 140.0
HKD1_k127_4430813_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 5.725e-195 632.0
HKD1_k127_4430813_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 316.0
HKD1_k127_4430813_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 327.0
HKD1_k127_4430813_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000005724 177.0
HKD1_k127_4430813_4 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000001017 164.0
HKD1_k127_4430813_5 cytochrome C oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000003576 174.0
HKD1_k127_4430813_6 Cytochrome c - - - 0.00000000000000000000000000000000000000006001 171.0
HKD1_k127_4457679_0 ABC transporter K06020 - 3.6.3.25 1.033e-262 818.0
HKD1_k127_4457679_1 B12 binding domain - - - 2.312e-224 704.0
HKD1_k127_4457679_10 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000002137 244.0
HKD1_k127_4457679_11 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000004824 229.0
HKD1_k127_4457679_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000001518 209.0
HKD1_k127_4457679_13 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000669 181.0
HKD1_k127_4457679_14 - - - - 0.0000000000000000000000000000002499 144.0
HKD1_k127_4457679_15 Metallo-peptidase family M12 - - - 0.0000000000000000000000000003354 115.0
HKD1_k127_4457679_16 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000004686 123.0
HKD1_k127_4457679_17 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000001721 123.0
HKD1_k127_4457679_18 Protein of unknown function (DUF983) - - - 0.00000000003704 70.0
HKD1_k127_4457679_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 4.262e-222 704.0
HKD1_k127_4457679_20 salt-induced outer membrane protein K07283 - - 0.0000008934 60.0
HKD1_k127_4457679_3 IgA Peptidase M64 - - - 1.032e-210 682.0
HKD1_k127_4457679_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 491.0
HKD1_k127_4457679_5 guanyl-nucleotide exchange factor activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 357.0
HKD1_k127_4457679_6 Beta-lactamase superfamily domain K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005477 267.0
HKD1_k127_4457679_7 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006283 265.0
HKD1_k127_4457679_8 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001728 266.0
HKD1_k127_4457679_9 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000002678 232.0
HKD1_k127_4469003_0 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 379.0
HKD1_k127_4469003_1 Acts as a magnesium transporter K06213 - - 0.0001023 50.0
HKD1_k127_4528659_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 554.0
HKD1_k127_4528659_1 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 511.0
HKD1_k127_4528659_10 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000003782 88.0
HKD1_k127_4528659_11 response to oxidative stress - - - 0.00000000008065 72.0
HKD1_k127_4528659_12 - - - - 0.00000003828 60.0
HKD1_k127_4528659_13 PFAM ferredoxin K08954 - - 0.00001155 52.0
HKD1_k127_4528659_14 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00006061 56.0
HKD1_k127_4528659_15 Sugar (and other) transporter - - - 0.0006466 48.0
HKD1_k127_4528659_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 365.0
HKD1_k127_4528659_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 329.0
HKD1_k127_4528659_4 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005688 293.0
HKD1_k127_4528659_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000005435 255.0
HKD1_k127_4528659_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000001834 116.0
HKD1_k127_4528659_7 Diguanylate cyclase - - - 0.00000000000000000001628 104.0
HKD1_k127_4528659_8 Smr domain - - - 0.0000000000000000003608 94.0
HKD1_k127_4528659_9 Iron-binding zinc finger CDGSH type K05710 - - 0.00000000000000287 78.0
HKD1_k127_4533021_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 391.0
HKD1_k127_4533021_1 Metallo-peptidase family M12 - - - 0.000000000000000000000000000001036 123.0
HKD1_k127_454938_0 Involved in the tonB-independent uptake of proteins - - - 6.598e-196 640.0
HKD1_k127_454938_1 Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003281 282.0
HKD1_k127_454938_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
HKD1_k127_454938_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000002704 134.0
HKD1_k127_454938_4 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.000000000000000000000000000004389 133.0
HKD1_k127_454938_5 ECF sigma factor K03088 - - 0.00000000000000000000000022 119.0
HKD1_k127_454938_6 cytochrome C oxidase K02275 - 1.9.3.1 0.0000000000000002654 90.0
HKD1_k127_4578955_0 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 351.0
HKD1_k127_4578955_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 274.0
HKD1_k127_4578955_2 ATP hydrolysis coupled proton transport K02123 - - 0.00000000000000000000000000000000000000006772 174.0
HKD1_k127_4578955_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000002473 104.0
HKD1_k127_4578955_4 PFAM Outer membrane efflux protein - - - 0.000000002113 70.0
HKD1_k127_457903_0 Insulinase (Peptidase family M16) K07263 - - 3.485e-196 622.0
HKD1_k127_457903_1 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 506.0
HKD1_k127_457903_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 442.0
HKD1_k127_457903_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 323.0
HKD1_k127_457903_4 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003553 263.0
HKD1_k127_457903_5 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000002335 245.0
HKD1_k127_4608504_0 Fumarase C C-terminus K01744 - 4.3.1.1 1.312e-197 653.0
HKD1_k127_4608504_1 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 460.0
HKD1_k127_4608504_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 313.0
HKD1_k127_4608504_3 helix_turn_helix, Lux Regulon K11712,K14987 - - 0.000000000000000000000000000000000000000000000000002391 203.0
HKD1_k127_4608504_4 response regulator receiver K13041 - - 0.000000000000000000000000000002609 124.0
HKD1_k127_4632162_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.115e-260 829.0
HKD1_k127_4632162_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 4.613e-241 775.0
HKD1_k127_4632162_2 Protein kinase domain K12132 - 2.7.11.1 3.24e-238 766.0
HKD1_k127_4632162_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000004706 170.0
HKD1_k127_4632162_4 - - - - 0.000000000000000000006799 94.0
HKD1_k127_4632162_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000002463 92.0
HKD1_k127_4635781_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.596e-265 829.0
HKD1_k127_4635781_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 494.0
HKD1_k127_4635781_10 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000001177 233.0
HKD1_k127_4635781_11 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000004406 221.0
HKD1_k127_4635781_12 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000007126 196.0
HKD1_k127_4635781_13 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000009174 191.0
HKD1_k127_4635781_14 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000005153 196.0
HKD1_k127_4635781_15 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000177 175.0
HKD1_k127_4635781_16 WYL domain - - - 0.000000000000000000000000000000000000000003421 173.0
HKD1_k127_4635781_17 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000008596 171.0
HKD1_k127_4635781_18 Belongs to the BshC family K22136 - - 0.000000000000000000000000000002259 137.0
HKD1_k127_4635781_19 - - - - 0.000000000000000000000000000008327 130.0
HKD1_k127_4635781_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 439.0
HKD1_k127_4635781_20 Uncharacterized protein family UPF0029 - - - 0.0000000000000000000000003042 122.0
HKD1_k127_4635781_21 peptidyl-tyrosine sulfation - - - 0.000000000000000000002534 111.0
HKD1_k127_4635781_22 cell redox homeostasis - - - 0.000000000000000000002581 107.0
HKD1_k127_4635781_23 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000004379 88.0
HKD1_k127_4635781_24 Preprotein translocase SecG subunit K03075 - - 0.00000000000001171 79.0
HKD1_k127_4635781_25 MerR HTH family regulatory protein K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000006694 62.0
HKD1_k127_4635781_26 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000002501 53.0
HKD1_k127_4635781_27 DoxX K16937 - 1.8.5.2 0.000007034 55.0
HKD1_k127_4635781_3 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 417.0
HKD1_k127_4635781_4 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 418.0
HKD1_k127_4635781_5 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 390.0
HKD1_k127_4635781_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 376.0
HKD1_k127_4635781_7 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 343.0
HKD1_k127_4635781_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001453 287.0
HKD1_k127_4635781_9 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001756 264.0
HKD1_k127_474118_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 286.0
HKD1_k127_474118_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000002691 206.0
HKD1_k127_474118_2 COGs COG5305 membrane protein - - - 0.00001216 57.0
HKD1_k127_4961768_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 564.0
HKD1_k127_4961768_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 507.0
HKD1_k127_4961768_10 Glyoxalase-like domain - - - 0.0000000000000000000000000000005169 130.0
HKD1_k127_4961768_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 411.0
HKD1_k127_4961768_3 FAD dependent oxidoreductase K00273 - 1.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 314.0
HKD1_k127_4961768_4 XdhC Rossmann domain - - - 0.0000000000000000000000000000000000000000000000000000008373 205.0
HKD1_k127_4961768_5 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000002597 177.0
HKD1_k127_4961768_6 MobA-Related Protein K07141 - 2.7.7.76 0.0000000000000000000000000000000000000001123 169.0
HKD1_k127_4961768_7 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000003586 170.0
HKD1_k127_4961768_8 metallochaperone-like domain K07402 - - 0.0000000000000000000000000000000000004379 153.0
HKD1_k127_4961768_9 Imidazolonepropionase and related - - - 0.000000000000000000000000000000001974 134.0
HKD1_k127_49703_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 1.924e-254 797.0
HKD1_k127_49703_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 569.0
HKD1_k127_49703_2 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 377.0
HKD1_k127_49703_3 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 321.0
HKD1_k127_49703_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000001182 193.0
HKD1_k127_49703_5 FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000137 200.0
HKD1_k127_49703_6 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000000000004679 209.0
HKD1_k127_49703_7 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000001884 123.0
HKD1_k127_49703_8 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000004529 128.0
HKD1_k127_4984458_0 ABC transporter, transmembrane K11085 - - 9.457e-206 660.0
HKD1_k127_4984458_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 504.0
HKD1_k127_4984458_11 PFAM blue (type 1) copper domain protein - - - 0.000000005943 63.0
HKD1_k127_4984458_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 430.0
HKD1_k127_4984458_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001182 259.0
HKD1_k127_4984458_4 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000788 226.0
HKD1_k127_4984458_5 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000001451 172.0
HKD1_k127_4984458_6 photosynthesis - - - 0.000000000000000000000000000000000000000009812 165.0
HKD1_k127_4984458_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000002315 144.0
HKD1_k127_4984458_8 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000001879 145.0
HKD1_k127_4984458_9 Helix-turn-helix domain - - - 0.00000000000000000000000000000001183 134.0
HKD1_k127_4986289_0 Succinyl-CoA ligase like flavodoxin domain - - - 5.2e-249 794.0
HKD1_k127_4986289_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 387.0
HKD1_k127_4986289_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000173 116.0
HKD1_k127_4986289_11 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000000002437 116.0
HKD1_k127_4986289_12 Pas domain - - - 0.000000000000000000000009461 117.0
HKD1_k127_4986289_13 Universal stress protein K06149 - - 0.0000000000000003646 89.0
HKD1_k127_4986289_14 Heavy-metal resistance - - - 0.000000000006417 77.0
HKD1_k127_4986289_15 mRNA catabolic process K06950 - - 0.00000001443 63.0
HKD1_k127_4986289_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 386.0
HKD1_k127_4986289_3 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 317.0
HKD1_k127_4986289_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
HKD1_k127_4986289_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001716 275.0
HKD1_k127_4986289_6 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006064 249.0
HKD1_k127_4986289_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000002395 218.0
HKD1_k127_4986289_8 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000004088 215.0
HKD1_k127_4986289_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000007777 120.0
HKD1_k127_49989_0 Beta-lactamase - - - 4.747e-283 891.0
HKD1_k127_49989_1 FtsX-like permease family K02004 - - 6.433e-277 878.0
HKD1_k127_49989_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 351.0
HKD1_k127_49989_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000000000000000000000002974 213.0
HKD1_k127_49989_4 Rnd family efflux transporter mfp subunit K02005 - - 0.0000000008766 63.0
HKD1_k127_5029241_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 457.0
HKD1_k127_5029241_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 326.0
HKD1_k127_5029241_2 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003985 283.0
HKD1_k127_5029241_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000001392 250.0
HKD1_k127_5029241_4 PFAM MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000001434 191.0
HKD1_k127_5029241_5 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000006541 182.0
HKD1_k127_5029241_6 - - - - 0.000000000000000000000000000000000000876 142.0
HKD1_k127_5029241_7 Thioesterase K01075 - 3.1.2.23 0.00000000000000000001068 101.0
HKD1_k127_5029241_8 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000006496 68.0
HKD1_k127_5029241_9 PilZ domain - - - 0.00000162 55.0
HKD1_k127_5033812_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 347.0
HKD1_k127_5033812_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 332.0
HKD1_k127_5033812_2 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 354.0
HKD1_k127_5033812_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003925 276.0
HKD1_k127_5033812_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000114 143.0
HKD1_k127_5033812_5 Large extracellular alpha-helical protein - - - 0.000000000000000000000000000000003023 128.0
HKD1_k127_5033812_6 Belongs to the UPF0312 family - - - 0.0000000000000000000001359 115.0
HKD1_k127_5039380_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 506.0
HKD1_k127_5039380_1 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 0.0000000000000000000000000000148 123.0
HKD1_k127_5039380_2 Methionine biosynthesis protein MetW - - - 0.00000000000000000000015 105.0
HKD1_k127_5039380_3 response regulator - - - 0.0000000000000000006129 95.0
HKD1_k127_5042324_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.548e-210 670.0
HKD1_k127_5042324_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 540.0
HKD1_k127_5042324_10 molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000003188 244.0
HKD1_k127_5042324_11 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000003521 241.0
HKD1_k127_5042324_12 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000002709 205.0
HKD1_k127_5042324_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000007281 176.0
HKD1_k127_5042324_14 Psort location Cytoplasmic, score 8.96 K02841 - - 0.000000000000000000000000000000000000000000103 175.0
HKD1_k127_5042324_15 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000002096 175.0
HKD1_k127_5042324_16 PRC-barrel domain - - - 0.000000000000000000000000000000000000000003729 157.0
HKD1_k127_5042324_17 FAD binding domain - - - 0.000000000000000000000000000000001226 149.0
HKD1_k127_5042324_18 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000001079 126.0
HKD1_k127_5042324_19 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000006104 124.0
HKD1_k127_5042324_2 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 539.0
HKD1_k127_5042324_20 cellulose binding - - - 0.0000000000000000000000001232 123.0
HKD1_k127_5042324_21 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000006522 103.0
HKD1_k127_5042324_22 Regulatory protein, FmdB family - - - 0.000000000000000007874 86.0
HKD1_k127_5042324_23 Methyltransferase domain - - - 0.00000000000000009685 94.0
HKD1_k127_5042324_24 - - - - 0.000000000000002905 77.0
HKD1_k127_5042324_25 Alpha/beta hydrolase family - - - 0.00000000005177 76.0
HKD1_k127_5042324_3 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 486.0
HKD1_k127_5042324_4 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 456.0
HKD1_k127_5042324_5 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 443.0
HKD1_k127_5042324_6 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
HKD1_k127_5042324_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004282 282.0
HKD1_k127_5042324_8 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 293.0
HKD1_k127_5042324_9 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000857 281.0
HKD1_k127_5044459_0 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 428.0
HKD1_k127_5044459_1 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000001319 222.0
HKD1_k127_5044459_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000004071 189.0
HKD1_k127_5044459_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000005387 195.0
HKD1_k127_5044459_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000002555 122.0
HKD1_k127_5044459_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000001684 124.0
HKD1_k127_5044459_6 arylamine N-acetyltransferase activity - - - 0.00000000005128 76.0
HKD1_k127_5051782_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.687e-243 775.0
HKD1_k127_5051782_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.56e-209 688.0
HKD1_k127_5051782_10 LuxR family transcriptional regulator K03424 - - 0.0000000000000000000000000000000000000000000000000000000000006478 220.0
HKD1_k127_5051782_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000007867 208.0
HKD1_k127_5051782_12 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000007807 183.0
HKD1_k127_5051782_13 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000003065 179.0
HKD1_k127_5051782_14 STAS domain K04749 - - 0.0000000000000000000000000000000005219 135.0
HKD1_k127_5051782_15 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000006873 143.0
HKD1_k127_5051782_16 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002529 128.0
HKD1_k127_5051782_17 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000006018 115.0
HKD1_k127_5051782_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000585 106.0
HKD1_k127_5051782_19 Zincin-like metallopeptidase - - - 0.00000000000000000000002436 113.0
HKD1_k127_5051782_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 574.0
HKD1_k127_5051782_20 - - - - 0.0000000000000000000001906 109.0
HKD1_k127_5051782_21 Protein of unknown function (DUF2905) - - - 0.0000000000000000001012 90.0
HKD1_k127_5051782_22 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000003358 89.0
HKD1_k127_5051782_23 Protein of unknown function (DUF503) K09764 - - 0.000000000000006868 78.0
HKD1_k127_5051782_24 protein conserved in archaea - - - 0.000000002218 69.0
HKD1_k127_5051782_25 Bacterial antitoxin of type II TA system, VapB - - - 0.00000001646 58.0
HKD1_k127_5051782_26 nuclease activity - - - 0.00000004458 67.0
HKD1_k127_5051782_27 TIGRFAM TonB family C-terminal domain K03832 - - 0.000004985 59.0
HKD1_k127_5051782_28 CAAX protease self-immunity K07052 - - 0.00009875 53.0
HKD1_k127_5051782_3 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 485.0
HKD1_k127_5051782_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 434.0
HKD1_k127_5051782_5 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 384.0
HKD1_k127_5051782_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 382.0
HKD1_k127_5051782_7 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 346.0
HKD1_k127_5051782_8 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 348.0
HKD1_k127_5051782_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
HKD1_k127_5076752_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 4.745e-252 800.0
HKD1_k127_5076752_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 402.0
HKD1_k127_5123353_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.2e-322 1004.0
HKD1_k127_5123353_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.199e-219 694.0
HKD1_k127_5123353_10 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005235 278.0
HKD1_k127_5123353_11 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009945 282.0
HKD1_k127_5123353_12 COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000738 258.0
HKD1_k127_5123353_13 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001428 241.0
HKD1_k127_5123353_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000002071 167.0
HKD1_k127_5123353_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000004293 148.0
HKD1_k127_5123353_16 Protein kinase domain - - - 0.000000000000000000000000000000000006647 158.0
HKD1_k127_5123353_17 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000004553 135.0
HKD1_k127_5123353_18 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000009475 132.0
HKD1_k127_5123353_19 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000006873 135.0
HKD1_k127_5123353_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 540.0
HKD1_k127_5123353_20 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000004589 116.0
HKD1_k127_5123353_21 Protein of unknown function (DUF1587) - - - 0.0000000000000000004017 102.0
HKD1_k127_5123353_22 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000006193 82.0
HKD1_k127_5123353_24 XdhC and CoxI family - - - 0.000000003913 58.0
HKD1_k127_5123353_25 FG-GAP repeat - - - 0.0000008391 57.0
HKD1_k127_5123353_26 DNA-templated transcription, initiation K03088 - - 0.000001662 57.0
HKD1_k127_5123353_27 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000002543 54.0
HKD1_k127_5123353_28 helix_turn_helix, Lux Regulon - - - 0.000008044 52.0
HKD1_k127_5123353_3 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 480.0
HKD1_k127_5123353_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 447.0
HKD1_k127_5123353_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 413.0
HKD1_k127_5123353_6 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 421.0
HKD1_k127_5123353_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 357.0
HKD1_k127_5123353_8 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 350.0
HKD1_k127_5123353_9 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 379.0
HKD1_k127_5137505_0 Involved in the tonB-independent uptake of proteins - - - 2.014e-229 737.0
HKD1_k127_5137505_1 Involved in the tonB-independent uptake of proteins - - - 4.582e-228 734.0
HKD1_k127_5137505_2 Involved in the tonB-independent uptake of proteins - - - 5.499e-225 741.0
HKD1_k127_5137505_3 Involved in the tonB-independent uptake of proteins - - - 3.564e-206 677.0
HKD1_k127_5137505_4 Involved in the tonB-independent uptake of proteins - - - 6.53e-198 647.0
HKD1_k127_5137505_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 527.0
HKD1_k127_5137505_6 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 437.0
HKD1_k127_5137505_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000009717 211.0
HKD1_k127_5139506_0 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 559.0
HKD1_k127_5139506_1 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 357.0
HKD1_k127_5139506_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001403 267.0
HKD1_k127_5139506_3 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000001546 223.0
HKD1_k127_5139506_4 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000007103 211.0
HKD1_k127_5139506_5 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000583 206.0
HKD1_k127_5139506_6 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000001704 189.0
HKD1_k127_5139506_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000001119 140.0
HKD1_k127_5139506_8 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000001423 129.0
HKD1_k127_5139506_9 SpoIIAA-like - - - 0.00000122 57.0
HKD1_k127_5140507_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 355.0
HKD1_k127_5140507_1 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
HKD1_k127_5140507_2 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000006595 227.0
HKD1_k127_5140507_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000001916 156.0
HKD1_k127_5140507_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000523 133.0
HKD1_k127_5140507_5 PFAM membrane-bound metal-dependent hydrolase K07038 - - 0.000000000000000000000000001913 125.0
HKD1_k127_5140507_6 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000003023 123.0
HKD1_k127_5140507_7 Thioesterase-like superfamily K07107 - - 0.000000000000000002706 93.0
HKD1_k127_5140507_8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000004167 81.0
HKD1_k127_5151773_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0 1052.0
HKD1_k127_5151773_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 9.477e-267 846.0
HKD1_k127_5151773_10 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000004568 240.0
HKD1_k127_5151773_11 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000005044 240.0
HKD1_k127_5151773_12 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000002624 209.0
HKD1_k127_5151773_13 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000001495 228.0
HKD1_k127_5151773_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.00000000000000000000000000000000000000000000002375 195.0
HKD1_k127_5151773_15 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000002521 152.0
HKD1_k127_5151773_16 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000001674 124.0
HKD1_k127_5151773_17 Diguanylate cyclase K07315 - 3.1.3.3 0.00000000000000000000000006731 122.0
HKD1_k127_5151773_18 Putative DNA-binding domain - - - 0.000000000000000002525 98.0
HKD1_k127_5151773_19 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000004483 87.0
HKD1_k127_5151773_2 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 618.0
HKD1_k127_5151773_20 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000003706 94.0
HKD1_k127_5151773_21 S4 RNA-binding domain K04762 - - 0.0000000000000007143 85.0
HKD1_k127_5151773_22 - - - - 0.00000000000000196 85.0
HKD1_k127_5151773_24 DNA-sulfur modification-associated - - - 0.000002249 60.0
HKD1_k127_5151773_25 - - - - 0.00000922 57.0
HKD1_k127_5151773_26 - - - - 0.0005558 48.0
HKD1_k127_5151773_3 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 467.0
HKD1_k127_5151773_4 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 435.0
HKD1_k127_5151773_6 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 413.0
HKD1_k127_5151773_7 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 350.0
HKD1_k127_5151773_8 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 325.0
HKD1_k127_5151773_9 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 320.0
HKD1_k127_5152350_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 407.0
HKD1_k127_5152350_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 317.0
HKD1_k127_5152350_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000004527 104.0
HKD1_k127_5161515_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1255.0
HKD1_k127_5161515_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 2.276e-291 918.0
HKD1_k127_5161515_10 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 577.0
HKD1_k127_5161515_101 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00001001 53.0
HKD1_k127_5161515_102 Tetratricopeptide repeats - - - 0.00001849 57.0
HKD1_k127_5161515_103 Tetratricopeptide repeat - - - 0.0002695 52.0
HKD1_k127_5161515_11 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 571.0
HKD1_k127_5161515_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 498.0
HKD1_k127_5161515_13 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 469.0
HKD1_k127_5161515_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 436.0
HKD1_k127_5161515_15 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 433.0
HKD1_k127_5161515_16 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 417.0
HKD1_k127_5161515_17 Dihydroxyacetone kinase family K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 432.0
HKD1_k127_5161515_18 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 434.0
HKD1_k127_5161515_19 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 393.0
HKD1_k127_5161515_2 malic protein domain protein K00029 - 1.1.1.40 1.992e-290 910.0
HKD1_k127_5161515_20 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 421.0
HKD1_k127_5161515_21 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 407.0
HKD1_k127_5161515_22 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 376.0
HKD1_k127_5161515_23 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 362.0
HKD1_k127_5161515_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 363.0
HKD1_k127_5161515_25 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 341.0
HKD1_k127_5161515_26 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 351.0
HKD1_k127_5161515_27 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 345.0
HKD1_k127_5161515_28 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 337.0
HKD1_k127_5161515_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 331.0
HKD1_k127_5161515_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.199e-242 769.0
HKD1_k127_5161515_30 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 311.0
HKD1_k127_5161515_31 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 328.0
HKD1_k127_5161515_32 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 299.0
HKD1_k127_5161515_33 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 286.0
HKD1_k127_5161515_34 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003033 278.0
HKD1_k127_5161515_35 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001368 279.0
HKD1_k127_5161515_36 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 274.0
HKD1_k127_5161515_37 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000004773 248.0
HKD1_k127_5161515_38 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002858 247.0
HKD1_k127_5161515_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000007103 239.0
HKD1_k127_5161515_4 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 4.469e-225 702.0
HKD1_k127_5161515_40 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 245.0
HKD1_k127_5161515_41 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000001886 239.0
HKD1_k127_5161515_42 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000006133 215.0
HKD1_k127_5161515_43 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000001208 214.0
HKD1_k127_5161515_44 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000001389 214.0
HKD1_k127_5161515_45 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000002942 205.0
HKD1_k127_5161515_46 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000003109 201.0
HKD1_k127_5161515_47 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000005315 188.0
HKD1_k127_5161515_48 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000002971 184.0
HKD1_k127_5161515_49 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000004059 192.0
HKD1_k127_5161515_5 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 585.0
HKD1_k127_5161515_50 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000007676 202.0
HKD1_k127_5161515_51 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000008797 179.0
HKD1_k127_5161515_52 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000004819 173.0
HKD1_k127_5161515_53 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000006819 191.0
HKD1_k127_5161515_54 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000002782 181.0
HKD1_k127_5161515_55 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000007397 166.0
HKD1_k127_5161515_56 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000001082 157.0
HKD1_k127_5161515_57 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000002285 163.0
HKD1_k127_5161515_58 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000003711 153.0
HKD1_k127_5161515_59 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001989 161.0
HKD1_k127_5161515_6 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 585.0
HKD1_k127_5161515_60 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000002005 166.0
HKD1_k127_5161515_61 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000005326 150.0
HKD1_k127_5161515_62 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000005993 145.0
HKD1_k127_5161515_63 HD domain - - - 0.000000000000000000000000000000001422 151.0
HKD1_k127_5161515_64 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000005082 138.0
HKD1_k127_5161515_65 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000009148 130.0
HKD1_k127_5161515_66 G-D-S-L family lipolytic protein - - - 0.0000000000000000000000000000206 137.0
HKD1_k127_5161515_67 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000006638 137.0
HKD1_k127_5161515_68 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000144 132.0
HKD1_k127_5161515_69 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000395 122.0
HKD1_k127_5161515_7 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 574.0
HKD1_k127_5161515_70 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000002701 114.0
HKD1_k127_5161515_71 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000002841 127.0
HKD1_k127_5161515_73 Diguanylate cyclase - - - 0.000000000000000000000000007981 126.0
HKD1_k127_5161515_74 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K13939,K13941 GO:0003674,GO:0003824,GO:0003848,GO:0004150,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016772,GO:0016778,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019752,GO:0031967,GO:0031975,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3,4.1.2.25 0.00000000000000000000000001734 120.0
HKD1_k127_5161515_77 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000001456 115.0
HKD1_k127_5161515_78 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05580 - 1.6.5.3 0.00000000000000000000001231 108.0
HKD1_k127_5161515_8 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 578.0
HKD1_k127_5161515_80 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000001586 108.0
HKD1_k127_5161515_83 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000004808 109.0
HKD1_k127_5161515_84 Preprotein translocase subunit K03210 - - 0.000000000000000000005707 97.0
HKD1_k127_5161515_87 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000007143 92.0
HKD1_k127_5161515_88 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000001237 87.0
HKD1_k127_5161515_89 ig-like, plexins, transcription factors - - - 0.000000000000000007663 98.0
HKD1_k127_5161515_9 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 553.0
HKD1_k127_5161515_92 Roadblock/LC7 domain - - - 0.00000000000002363 78.0
HKD1_k127_5161515_94 - - - - 0.0000000000001298 84.0
HKD1_k127_5161515_95 cyclic nucleotide-binding - - - 0.0000000000001679 83.0
HKD1_k127_5161515_96 repeat-containing protein - - - 0.0000000000003977 83.0
HKD1_k127_5161515_97 Protein of unknown function (FYDLN_acid) - - - 0.000000000001491 72.0
HKD1_k127_5161515_98 PFAM Fimbrial assembly family protein K02663 - - 0.0000000002078 72.0
HKD1_k127_5161515_99 Tetratricopeptide repeat K08309 - - 0.0000000008054 74.0
HKD1_k127_5174917_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 372.0
HKD1_k127_5174917_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000002105 209.0
HKD1_k127_5187631_0 cluster binding protein K18929 - - 6.908e-214 674.0
HKD1_k127_5187631_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 6.52e-204 650.0
HKD1_k127_5187631_10 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000007697 247.0
HKD1_k127_5187631_11 membrane - - - 0.0000000000000000000000000000000000000000000000000000000005349 208.0
HKD1_k127_5187631_12 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000000000000000000000000000007225 172.0
HKD1_k127_5187631_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000003215 63.0
HKD1_k127_5187631_14 Putative MetA-pathway of phenol degradation - - - 0.000000139 53.0
HKD1_k127_5187631_2 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 488.0
HKD1_k127_5187631_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 490.0
HKD1_k127_5187631_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 444.0
HKD1_k127_5187631_5 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 362.0
HKD1_k127_5187631_6 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 325.0
HKD1_k127_5187631_7 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 320.0
HKD1_k127_5187631_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 301.0
HKD1_k127_5187631_9 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000006331 241.0
HKD1_k127_5190961_0 GTP-binding protein TypA K06207 - - 5.206e-203 649.0
HKD1_k127_5190961_1 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 601.0
HKD1_k127_5190961_10 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000001151 151.0
HKD1_k127_5190961_11 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000006626 99.0
HKD1_k127_5190961_2 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 416.0
HKD1_k127_5190961_3 TIGRFAM cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 329.0
HKD1_k127_5190961_4 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 297.0
HKD1_k127_5190961_5 COG2931 RTX toxins and related Ca2 -binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000002559 258.0
HKD1_k127_5190961_6 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000289 232.0
HKD1_k127_5190961_7 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000000003891 151.0
HKD1_k127_5190961_8 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000006884 157.0
HKD1_k127_5190961_9 - - - - 0.00000000000000000000000000000000006443 141.0
HKD1_k127_5200262_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.621e-201 647.0
HKD1_k127_5200262_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000001113 90.0
HKD1_k127_5200262_2 Sigma-70 region 2 K03088 - - 0.000000000000002017 88.0
HKD1_k127_5200262_3 Cysteine dioxygenase type I - - - 0.0000000001108 69.0
HKD1_k127_5200262_4 LTXXQ motif family protein K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507 - 0.000001692 57.0
HKD1_k127_5214783_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 361.0
HKD1_k127_5214783_1 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 346.0
HKD1_k127_5214783_2 Cytochrome C oxidase, cbb3-type, subunit III K19713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 0.0000000000000000000000000000000000000006692 159.0
HKD1_k127_5214783_3 Putative DNA-binding domain - - - 0.00000000000000000002251 103.0
HKD1_k127_5214783_4 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000001495 74.0
HKD1_k127_5214783_5 PFAM sigma-70 region 2 domain protein K03088 - - 0.000002599 50.0
HKD1_k127_5218321_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 403.0
HKD1_k127_5218321_1 NmrA-like family K07118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 330.0
HKD1_k127_5218321_2 - - - - 0.00000000000000000000000000000002969 130.0
HKD1_k127_5219900_0 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 307.0
HKD1_k127_5219900_1 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000021 288.0
HKD1_k127_5219900_2 ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004103 269.0
HKD1_k127_5219900_3 PFAM Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000000000000000122 230.0
HKD1_k127_5219900_4 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000000000005879 202.0
HKD1_k127_5224350_0 YCII-related domain - - - 0.0000000000000000000000001407 116.0
HKD1_k127_5224350_1 - - - - 0.0000005297 56.0
HKD1_k127_5304366_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 563.0
HKD1_k127_5304366_1 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 527.0
HKD1_k127_5304366_10 transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 340.0
HKD1_k127_5304366_11 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 322.0
HKD1_k127_5304366_12 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 332.0
HKD1_k127_5304366_13 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 295.0
HKD1_k127_5304366_14 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002106 244.0
HKD1_k127_5304366_15 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000001499 244.0
HKD1_k127_5304366_16 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000002242 239.0
HKD1_k127_5304366_17 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000001673 231.0
HKD1_k127_5304366_18 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000001212 228.0
HKD1_k127_5304366_19 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000006137 201.0
HKD1_k127_5304366_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 477.0
HKD1_k127_5304366_20 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000003184 197.0
HKD1_k127_5304366_21 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000003288 189.0
HKD1_k127_5304366_22 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001171 182.0
HKD1_k127_5304366_23 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000006455 192.0
HKD1_k127_5304366_24 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.0000000000000000000000000000000000000003516 158.0
HKD1_k127_5304366_25 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000001493 158.0
HKD1_k127_5304366_26 TPM domain - - - 0.00000000000000000000000000000000000003468 147.0
HKD1_k127_5304366_27 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000002402 145.0
HKD1_k127_5304366_28 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000002883 136.0
HKD1_k127_5304366_29 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000008416 151.0
HKD1_k127_5304366_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 442.0
HKD1_k127_5304366_30 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000003135 134.0
HKD1_k127_5304366_31 phosphate ion binding K02040 - - 0.00000000000000000000000000001137 123.0
HKD1_k127_5304366_32 - - - - 0.000000000000000000000000004171 114.0
HKD1_k127_5304366_33 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000002305 112.0
HKD1_k127_5304366_34 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000004192 104.0
HKD1_k127_5304366_35 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000003014 96.0
HKD1_k127_5304366_36 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000001753 83.0
HKD1_k127_5304366_37 Phosphoglycerate mutase family K08296 - - 0.000000000000003467 81.0
HKD1_k127_5304366_38 Binds the 23S rRNA K02909 - - 0.000000000002573 66.0
HKD1_k127_5304366_39 DNA polymerase III, delta' K02340 - 2.7.7.7 0.000000001566 70.0
HKD1_k127_5304366_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 401.0
HKD1_k127_5304366_40 peptidyl-prolyl cis-trans isomerase activity K00645,K01802,K02597,K03769,K03770,K03771 - 2.3.1.39,5.2.1.8 0.000000005663 66.0
HKD1_k127_5304366_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 368.0
HKD1_k127_5304366_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 376.0
HKD1_k127_5304366_7 Four helix bundle sensory module for signal transduction K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 357.0
HKD1_k127_5304366_8 Peptidase S15 K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 362.0
HKD1_k127_5304366_9 Cardiolipin synthetase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 332.0
HKD1_k127_5310869_0 Polysulphide reductase, NrfD K00185 - - 2.29e-215 678.0
HKD1_k127_5310869_1 4Fe-4S dicluster domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 548.0
HKD1_k127_5310869_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 386.0
HKD1_k127_5310869_3 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000002775 234.0
HKD1_k127_5310869_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000006641 227.0
HKD1_k127_5310869_5 - - - - 0.000000000000549 76.0
HKD1_k127_533762_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 1.378e-239 745.0
HKD1_k127_533762_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 1.151e-224 702.0
HKD1_k127_533762_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.61e-197 621.0
HKD1_k127_533762_3 Cytochrome c - - - 1.302e-195 617.0
HKD1_k127_533762_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004764 282.0
HKD1_k127_5343370_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000004704 123.0
HKD1_k127_5343370_1 Secretin and TonB N terminus short domain K02453 - - 0.0000000000000000000000000000007964 141.0
HKD1_k127_5343370_2 Pilus assembly protein K02662 - - 0.00000008641 64.0
HKD1_k127_5351989_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 422.0
HKD1_k127_5351989_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 369.0
HKD1_k127_5351989_2 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000332 194.0
HKD1_k127_5351989_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000001901 134.0
HKD1_k127_5351989_4 PFAM NHL repeat containing protein - - - 0.0000000000000000001815 96.0
HKD1_k127_5371787_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 302.0
HKD1_k127_5371787_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 302.0
HKD1_k127_5371787_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000271 261.0
HKD1_k127_5371787_3 membrane K07058 - - 0.00000000000001543 86.0
HKD1_k127_5371787_4 - - - - 0.0004335 47.0
HKD1_k127_5453766_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 370.0
HKD1_k127_5453766_1 response regulator - - - 0.0000000000000000000000000000000000000000000008336 189.0
HKD1_k127_5453766_2 - - - - 0.000000000000000000000000000000000000000000007758 175.0
HKD1_k127_5453766_3 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000001342 164.0
HKD1_k127_5453766_4 Domain of unknown function (DUF4136) - - - 0.0000000000000000000004572 102.0
HKD1_k127_5453766_5 Domain of unknown function (DUF4136) - - - 0.00000000000000004444 89.0
HKD1_k127_5527132_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1447.0
HKD1_k127_5527132_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 6.004e-229 722.0
HKD1_k127_5527132_10 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000623 261.0
HKD1_k127_5527132_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000189 231.0
HKD1_k127_5527132_12 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
HKD1_k127_5527132_13 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001358 223.0
HKD1_k127_5527132_14 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000004195 201.0
HKD1_k127_5527132_15 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000793 198.0
HKD1_k127_5527132_16 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000002895 183.0
HKD1_k127_5527132_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001578 168.0
HKD1_k127_5527132_18 TOBE domain - - - 0.0000000000000000000000000000006786 126.0
HKD1_k127_5527132_19 Histidine kinase - - - 0.00000000000000000000000000001886 133.0
HKD1_k127_5527132_2 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 593.0
HKD1_k127_5527132_20 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000001385 100.0
HKD1_k127_5527132_21 Iron-sulfur cluster-binding domain - - - 0.00000000000000006296 94.0
HKD1_k127_5527132_22 Putative MetA-pathway of phenol degradation - - - 0.000000000000001142 88.0
HKD1_k127_5527132_23 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001118 63.0
HKD1_k127_5527132_24 - - - - 0.00009173 56.0
HKD1_k127_5527132_25 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0006272 51.0
HKD1_k127_5527132_3 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 406.0
HKD1_k127_5527132_4 outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 385.0
HKD1_k127_5527132_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 352.0
HKD1_k127_5527132_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 330.0
HKD1_k127_5527132_7 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 321.0
HKD1_k127_5527132_8 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000245 263.0
HKD1_k127_5527132_9 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001008 251.0
HKD1_k127_5684291_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 558.0
HKD1_k127_5684291_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 552.0
HKD1_k127_5684291_2 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 377.0
HKD1_k127_5684291_3 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000009606 230.0
HKD1_k127_5684291_4 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000001249 204.0
HKD1_k127_5684291_5 DoxX - - - 0.0000000000000000000000000000000000000000000000000128 184.0
HKD1_k127_5684291_6 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000002343 162.0
HKD1_k127_5684291_7 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000004575 140.0
HKD1_k127_5684291_8 - - - - 0.000000000000000000000000000000005882 132.0
HKD1_k127_5684291_9 PhoQ Sensor - - - 0.0000001122 54.0
HKD1_k127_571665_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.353e-268 842.0
HKD1_k127_571665_1 Urocanase C-terminal domain K01712 - 4.2.1.49 1.314e-246 778.0
HKD1_k127_571665_10 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 402.0
HKD1_k127_571665_11 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 409.0
HKD1_k127_571665_12 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 340.0
HKD1_k127_571665_13 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 331.0
HKD1_k127_571665_14 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 309.0
HKD1_k127_571665_15 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000002375 247.0
HKD1_k127_571665_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000005785 233.0
HKD1_k127_571665_17 PFAM Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002488 224.0
HKD1_k127_571665_18 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000000000001207 224.0
HKD1_k127_571665_19 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000003077 199.0
HKD1_k127_571665_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.77e-213 691.0
HKD1_k127_571665_20 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000007922 172.0
HKD1_k127_571665_21 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000001348 175.0
HKD1_k127_571665_22 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000001339 170.0
HKD1_k127_571665_23 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000000000000000006132 161.0
HKD1_k127_571665_24 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000009292 164.0
HKD1_k127_571665_25 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000009145 169.0
HKD1_k127_571665_26 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000002855 159.0
HKD1_k127_571665_27 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002022 148.0
HKD1_k127_571665_28 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000004664 141.0
HKD1_k127_571665_29 Could be involved in septation K06412 - - 0.000000000000000000000000000004623 123.0
HKD1_k127_571665_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 596.0
HKD1_k127_571665_30 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000005261 118.0
HKD1_k127_571665_31 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000002411 115.0
HKD1_k127_571665_32 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000004379 119.0
HKD1_k127_571665_33 Ribosomal protein S18 K02963 - - 0.000000000000000000000009213 109.0
HKD1_k127_571665_34 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000161 107.0
HKD1_k127_571665_35 Tetratricopeptide repeat - - - 0.000000000000000006035 99.0
HKD1_k127_571665_36 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000001184 87.0
HKD1_k127_571665_37 heat shock protein binding - - - 0.0000000000000000501 95.0
HKD1_k127_571665_4 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 509.0
HKD1_k127_571665_40 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 - 2.3.1.234 0.00000000000004068 81.0
HKD1_k127_571665_41 Domain of unknown function (DUF4126) - - - 0.0000000000006927 82.0
HKD1_k127_571665_42 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000001456 73.0
HKD1_k127_571665_43 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000003835 72.0
HKD1_k127_571665_44 YacP-like NYN domain - - - 0.000000004782 63.0
HKD1_k127_571665_45 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000665 62.0
HKD1_k127_571665_46 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0000003045 64.0
HKD1_k127_571665_47 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000001581 60.0
HKD1_k127_571665_48 Uroporphyrinogen-III synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.00007141 55.0
HKD1_k127_571665_49 Protein of unknown function (DUF465) - - - 0.0002586 47.0
HKD1_k127_571665_5 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 489.0
HKD1_k127_571665_50 Predicted membrane protein (DUF2232) - - - 0.0005468 51.0
HKD1_k127_571665_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 482.0
HKD1_k127_571665_7 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 472.0
HKD1_k127_571665_8 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
HKD1_k127_571665_9 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 417.0
HKD1_k127_5750136_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1051.0
HKD1_k127_5750136_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.157e-237 786.0
HKD1_k127_5750136_10 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 392.0
HKD1_k127_5750136_11 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 358.0
HKD1_k127_5750136_12 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 348.0
HKD1_k127_5750136_13 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001337 252.0
HKD1_k127_5750136_14 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000006698 239.0
HKD1_k127_5750136_15 dihydrofolate reductase activity K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000001494 236.0
HKD1_k127_5750136_16 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000001244 235.0
HKD1_k127_5750136_17 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000001432 231.0
HKD1_k127_5750136_18 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000003953 230.0
HKD1_k127_5750136_19 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000002653 213.0
HKD1_k127_5750136_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 5.241e-226 728.0
HKD1_k127_5750136_20 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000001599 198.0
HKD1_k127_5750136_21 Inner membrane component domain - - - 0.0000000000000000000000000000000000000000000000002098 194.0
HKD1_k127_5750136_22 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000003781 178.0
HKD1_k127_5750136_23 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000002106 194.0
HKD1_k127_5750136_24 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000007883 179.0
HKD1_k127_5750136_25 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000005886 176.0
HKD1_k127_5750136_26 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000008159 158.0
HKD1_k127_5750136_27 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000006658 171.0
HKD1_k127_5750136_28 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000002574 154.0
HKD1_k127_5750136_29 - - - - 0.000000000000000000000000000000000000979 151.0
HKD1_k127_5750136_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 2.976e-210 663.0
HKD1_k127_5750136_30 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000001638 142.0
HKD1_k127_5750136_31 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000003155 149.0
HKD1_k127_5750136_32 MgtC family K07507 - - 0.000000000000000000000000000000001651 149.0
HKD1_k127_5750136_33 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000002446 141.0
HKD1_k127_5750136_34 - - - - 0.000000000000000000000001109 120.0
HKD1_k127_5750136_35 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000432 109.0
HKD1_k127_5750136_36 - - - - 0.000000000000000000002032 106.0
HKD1_k127_5750136_37 carboxylic ester hydrolase activity - - - 0.0000000000000000004371 96.0
HKD1_k127_5750136_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.65e-199 632.0
HKD1_k127_5750136_40 Sigma-70, region 4 K03088 - - 0.0000000129 64.0
HKD1_k127_5750136_41 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00001739 51.0
HKD1_k127_5750136_42 Belongs to the peptidase S8 family K13276 GO:0005575,GO:0005576 - 0.00008423 52.0
HKD1_k127_5750136_43 Carboxypeptidase regulatory-like domain - - - 0.0002412 49.0
HKD1_k127_5750136_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 494.0
HKD1_k127_5750136_6 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 469.0
HKD1_k127_5750136_7 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 451.0
HKD1_k127_5750136_8 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 411.0
HKD1_k127_5750136_9 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 387.0
HKD1_k127_5783563_0 aminopeptidase N - - - 0.000000000000000000000000000000000002096 156.0
HKD1_k127_5783563_1 Pirin K06911 - - 0.000000000000000000001377 98.0
HKD1_k127_5789591_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002133 250.0
HKD1_k127_5789591_1 tryptophanase activity K01667 - 4.1.99.1 0.00000000000000000000000000002954 119.0
HKD1_k127_5789591_2 - - - - 0.00000000000000000003009 101.0
HKD1_k127_5789591_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000009492 79.0
HKD1_k127_5797014_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 1.135e-309 986.0
HKD1_k127_5797014_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 583.0
HKD1_k127_5797014_10 Permease, YjgP YjgQ - - - 0.000000000000000000000000000001285 130.0
HKD1_k127_5797014_11 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000005451 132.0
HKD1_k127_5797014_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 581.0
HKD1_k127_5797014_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 531.0
HKD1_k127_5797014_4 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 380.0
HKD1_k127_5797014_5 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000001103 238.0
HKD1_k127_5797014_6 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000002642 227.0
HKD1_k127_5797014_7 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000001526 193.0
HKD1_k127_5797014_8 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000002717 154.0
HKD1_k127_595003_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 3.756e-313 974.0
HKD1_k127_595003_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 576.0
HKD1_k127_595003_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 291.0
HKD1_k127_595003_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006368 278.0
HKD1_k127_595003_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000001979 114.0
HKD1_k127_6001585_0 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000008723 168.0
HKD1_k127_6001585_1 Aromatic acid exporter family member 1 - - - 0.0000000000000000000005467 99.0
HKD1_k127_6001585_2 Serine threonine protein kinase - - - 0.0000000000000002404 94.0
HKD1_k127_6055315_0 4Fe-4S binding domain - - - 2.518e-233 743.0
HKD1_k127_6055315_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 417.0
HKD1_k127_6055315_2 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 353.0
HKD1_k127_6055315_3 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 300.0
HKD1_k127_6055315_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003517 253.0
HKD1_k127_6063355_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 342.0
HKD1_k127_6063355_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000001119 160.0
HKD1_k127_6069087_0 Heat shock 70 kDa protein K04043 - - 2.79e-308 954.0
HKD1_k127_6069087_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.427e-208 660.0
HKD1_k127_6069087_10 ASPIC and UnbV - - - 0.0004092 53.0
HKD1_k127_6069087_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002444 246.0
HKD1_k127_6069087_3 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000009483 161.0
HKD1_k127_6069087_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000006906 153.0
HKD1_k127_6069087_5 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000000007056 120.0
HKD1_k127_6069087_6 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000002165 107.0
HKD1_k127_6069087_7 oxidoreductase activity - - - 0.00000000000000000005628 105.0
HKD1_k127_6069087_8 Domain of unknown function (DUF1844) - - - 0.000000001108 66.0
HKD1_k127_6069087_9 Domain of unknown function (DUF4388) - - - 0.00000004825 66.0
HKD1_k127_6077962_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 531.0
HKD1_k127_6077962_1 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000005891 293.0
HKD1_k127_6077962_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 267.0
HKD1_k127_6077962_3 hydrolase activity, acting on ester bonds - - - 0.0000000000000004805 89.0
HKD1_k127_6077962_4 Peptidase M56 K03646 - - 0.0000000005957 71.0
HKD1_k127_6081691_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1110.0
HKD1_k127_6081691_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.811e-260 815.0
HKD1_k127_6081691_10 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000001535 93.0
HKD1_k127_6081691_11 Sulfurtransferase - - - 0.000000000000003595 91.0
HKD1_k127_6081691_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 604.0
HKD1_k127_6081691_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000002324 177.0
HKD1_k127_6081691_4 Tautomerase enzyme - - - 0.0000000000000000000000000000000000001609 153.0
HKD1_k127_6081691_5 DinB family - - - 0.000000000000000000000000000000000001905 145.0
HKD1_k127_6081691_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000007747 136.0
HKD1_k127_6081691_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000008249 118.0
HKD1_k127_6081691_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000005728 97.0
HKD1_k127_6081691_9 PFAM Outer membrane efflux protein - - - 0.000000000000000103 93.0
HKD1_k127_6084457_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 507.0
HKD1_k127_6084457_1 chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 462.0
HKD1_k127_6084457_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 424.0
HKD1_k127_6084457_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 383.0
HKD1_k127_6084457_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 364.0
HKD1_k127_6084457_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 337.0
HKD1_k127_6084457_6 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 301.0
HKD1_k127_6084457_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 263.0
HKD1_k127_6084457_8 Cell division protein FtsQ K03589 - - 0.0000000000005041 78.0
HKD1_k127_6084457_9 lactoylglutathione lyase activity - - - 0.0000000001636 63.0
HKD1_k127_6095224_0 Amino acid permease - - - 1.706e-206 666.0
HKD1_k127_6095224_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 505.0
HKD1_k127_6095224_10 tetratricopeptide repeat - - - 0.00004318 56.0
HKD1_k127_6095224_11 Tetratricopeptide repeat-like domain - - - 0.0005033 50.0
HKD1_k127_6095224_2 abc transporter atp-binding protein K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 438.0
HKD1_k127_6095224_3 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 425.0
HKD1_k127_6095224_4 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 311.0
HKD1_k127_6095224_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003511 289.0
HKD1_k127_6095224_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000007067 199.0
HKD1_k127_6095224_7 iron-sulfur cluster assembly K07400 - - 0.000000000000000000000000000000000000000000001951 173.0
HKD1_k127_6095224_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000002642 153.0
HKD1_k127_6095224_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000008163 98.0
HKD1_k127_6100502_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.593e-201 646.0
HKD1_k127_6100502_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 524.0
HKD1_k127_6100502_10 - - - - 0.00000001904 65.0
HKD1_k127_6100502_11 - - - - 0.00000004904 65.0
HKD1_k127_6100502_12 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00003435 52.0
HKD1_k127_6100502_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 492.0
HKD1_k127_6100502_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 394.0
HKD1_k127_6100502_4 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 349.0
HKD1_k127_6100502_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 318.0
HKD1_k127_6100502_6 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 327.0
HKD1_k127_6100502_7 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000000000000000000000000000000005641 153.0
HKD1_k127_6100502_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000006897 108.0
HKD1_k127_6100502_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000001363 94.0
HKD1_k127_6130659_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2840.0
HKD1_k127_6130659_1 transmembrane transporter activity K03296 - - 7.581e-206 679.0
HKD1_k127_6130659_10 amino acid K03293,K16238,K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 426.0
HKD1_k127_6130659_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 362.0
HKD1_k127_6130659_12 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 351.0
HKD1_k127_6130659_13 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 342.0
HKD1_k127_6130659_14 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 331.0
HKD1_k127_6130659_15 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 333.0
HKD1_k127_6130659_16 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 301.0
HKD1_k127_6130659_17 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001704 274.0
HKD1_k127_6130659_18 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004003 267.0
HKD1_k127_6130659_19 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000001506 249.0
HKD1_k127_6130659_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 618.0
HKD1_k127_6130659_20 - - - - 0.000000000000000000000000000000000000000000000000001771 203.0
HKD1_k127_6130659_21 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000000007351 185.0
HKD1_k127_6130659_22 cytochrome - - - 0.0000000000000000000000000000000000000009142 160.0
HKD1_k127_6130659_23 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000006865 162.0
HKD1_k127_6130659_24 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000007913 140.0
HKD1_k127_6130659_25 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000000513 132.0
HKD1_k127_6130659_26 - - - - 0.000000000000000000000000000002922 140.0
HKD1_k127_6130659_27 - - - - 0.00000000000000000000000001254 127.0
HKD1_k127_6130659_28 MerR, DNA binding - - - 0.00000000000000000000000005546 126.0
HKD1_k127_6130659_29 PQQ enzyme repeat - - - 0.0000000000000000000001121 115.0
HKD1_k127_6130659_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 608.0
HKD1_k127_6130659_30 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000001714 107.0
HKD1_k127_6130659_31 YXWGXW repeat (2 copies) - - - 0.0000000000000000005202 90.0
HKD1_k127_6130659_32 Type III secretion system lipoprotein chaperone (YscW) - - - 0.000000000000001512 82.0
HKD1_k127_6130659_33 Regulatory protein - - - 0.000000000000007458 81.0
HKD1_k127_6130659_34 Domain of unknown function (DUF309) K09763 - - 0.00000000000005109 78.0
HKD1_k127_6130659_35 PFAM PKD domain containing protein - - - 0.00000000000009241 85.0
HKD1_k127_6130659_37 Nitrous oxide-stimulated promoter - - - 0.00002639 50.0
HKD1_k127_6130659_4 belongs to the aldehyde dehydrogenase family K00137 GO:0003674,GO:0003824,GO:0004029,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019145,GO:0033737,GO:0034641,GO:0042402,GO:0042802,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 1.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 578.0
HKD1_k127_6130659_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 569.0
HKD1_k127_6130659_6 Aminotransferase class-III K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 542.0
HKD1_k127_6130659_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 563.0
HKD1_k127_6130659_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 457.0
HKD1_k127_6130659_9 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 455.0
HKD1_k127_6137803_0 transcription factor binding K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 478.0
HKD1_k127_6137803_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000001172 215.0
HKD1_k127_6137803_2 Membrane - - - 0.00000000000000000000000000000000000008374 145.0
HKD1_k127_6137803_3 - - - - 0.00004166 50.0
HKD1_k127_6137803_4 Putative zinc-finger - - - 0.0009642 46.0
HKD1_k127_6181329_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0016829,GO:0016830,GO:0016833 4.1.3.1 0.0 1184.0
HKD1_k127_6181329_1 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1090.0
HKD1_k127_6181329_10 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 402.0
HKD1_k127_6181329_11 short-chain dehydrogenase K13774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 292.0
HKD1_k127_6181329_12 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 293.0
HKD1_k127_6181329_13 PFAM ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001812 308.0
HKD1_k127_6181329_14 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001799 286.0
HKD1_k127_6181329_15 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008992 278.0
HKD1_k127_6181329_16 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 279.0
HKD1_k127_6181329_17 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000001656 216.0
HKD1_k127_6181329_18 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000004779 210.0
HKD1_k127_6181329_19 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000837 203.0
HKD1_k127_6181329_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 576.0
HKD1_k127_6181329_20 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000000000000001273 172.0
HKD1_k127_6181329_21 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000001269 164.0
HKD1_k127_6181329_22 Transcriptional regulator - - - 0.0000000000000000000000000000000000000005508 156.0
HKD1_k127_6181329_23 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000002104 152.0
HKD1_k127_6181329_24 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000002314 124.0
HKD1_k127_6181329_25 MoaE protein K21142 - 2.8.1.12 0.0000000000000004671 80.0
HKD1_k127_6181329_26 Bacterial membrane protein YfhO - - - 0.00000000000009641 85.0
HKD1_k127_6181329_27 Cytochrome c K03889 - - 0.00000007367 65.0
HKD1_k127_6181329_3 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 546.0
HKD1_k127_6181329_4 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 512.0
HKD1_k127_6181329_5 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 499.0
HKD1_k127_6181329_6 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 477.0
HKD1_k127_6181329_7 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 400.0
HKD1_k127_6181329_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 371.0
HKD1_k127_6181329_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 368.0
HKD1_k127_6202346_0 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 352.0
HKD1_k127_6202346_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 353.0
HKD1_k127_6202346_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000144 248.0
HKD1_k127_6202346_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000007449 230.0
HKD1_k127_6202346_4 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000003685 130.0
HKD1_k127_6202346_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000343 106.0
HKD1_k127_6202346_6 integral membrane protein - - - 0.0000000000000007088 91.0
HKD1_k127_6202346_7 Pfam Cation efflux - - - 0.0000000000000317 81.0
HKD1_k127_620789_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1e-323 1002.0
HKD1_k127_620789_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000006088 214.0
HKD1_k127_620789_2 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000002804 215.0
HKD1_k127_620789_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000003344 191.0
HKD1_k127_620789_4 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000000000000000000000000000000001695 170.0
HKD1_k127_620789_5 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000001202 121.0
HKD1_k127_620789_6 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000697 128.0
HKD1_k127_620789_7 sequence-specific DNA binding K07729 - - 0.000000000000000000503 89.0
HKD1_k127_620789_8 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000002874 88.0
HKD1_k127_62225_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1071.0
HKD1_k127_62225_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 338.0
HKD1_k127_62225_2 TIGRFAM diguanylate cyclase - - - 0.0000000000000000000000000000003597 133.0
HKD1_k127_62225_3 PFAM Peptidase M23 - - - 0.000000000000000001973 97.0
HKD1_k127_62225_4 O-Antigen ligase - - - 0.0000003785 63.0
HKD1_k127_6232144_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 383.0
HKD1_k127_6232144_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 333.0
HKD1_k127_6232144_2 transglycosylase K08309 - - 0.0000000000000000000000000000000001159 154.0
HKD1_k127_6232144_3 nuclear chromosome segregation - - - 0.00000000000000000001414 105.0
HKD1_k127_6232144_4 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006234 90.0
HKD1_k127_6232144_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0006148 46.0
HKD1_k127_6242620_0 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000003749 202.0
HKD1_k127_6242620_1 Pkd domain containing protein K01337 - 3.4.21.50 0.0000000000000000004501 100.0
HKD1_k127_6249243_0 Dehydrogenase E1 component K11381 - 1.2.4.4 3.192e-281 882.0
HKD1_k127_6249243_1 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 542.0
HKD1_k127_6249243_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 447.0
HKD1_k127_6249243_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 451.0
HKD1_k127_6249243_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001379 286.0
HKD1_k127_6249243_5 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000003355 267.0
HKD1_k127_6249243_6 Oxidoreductase NAD-binding domain K02823 - - 0.000000000000000000000000000000000000004139 155.0
HKD1_k127_6269294_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000001718 219.0
HKD1_k127_6269294_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000002408 155.0
HKD1_k127_6269294_2 Bacterial membrane protein YfhO - - - 0.00000000000000000000000003948 126.0
HKD1_k127_6271806_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 350.0
HKD1_k127_6271806_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 329.0
HKD1_k127_6271806_2 Type II transport protein GspH K08084 - - 0.00004373 53.0
HKD1_k127_6274529_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001771 272.0
HKD1_k127_6274529_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001552 245.0
HKD1_k127_6274529_2 selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000003984 196.0
HKD1_k127_6288638_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1075.0
HKD1_k127_6288638_1 Heat shock 70 kDa protein K04043 - - 3.98e-239 753.0
HKD1_k127_6288638_10 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 339.0
HKD1_k127_6288638_11 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001698 271.0
HKD1_k127_6288638_12 Transglycosylase SLT domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003298 264.0
HKD1_k127_6288638_13 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000005656 239.0
HKD1_k127_6288638_14 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000206 216.0
HKD1_k127_6288638_15 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000007703 197.0
HKD1_k127_6288638_16 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000002666 184.0
HKD1_k127_6288638_17 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000001873 147.0
HKD1_k127_6288638_18 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000005091 154.0
HKD1_k127_6288638_19 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000005524 131.0
HKD1_k127_6288638_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.553e-196 662.0
HKD1_k127_6288638_20 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000004067 121.0
HKD1_k127_6288638_21 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000915 104.0
HKD1_k127_6288638_22 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000001112 91.0
HKD1_k127_6288638_23 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000006717 72.0
HKD1_k127_6288638_24 - - - - 0.000307 51.0
HKD1_k127_6288638_25 Tetratricopeptide repeat - - - 0.0003692 52.0
HKD1_k127_6288638_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 612.0
HKD1_k127_6288638_4 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 546.0
HKD1_k127_6288638_5 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 486.0
HKD1_k127_6288638_6 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 471.0
HKD1_k127_6288638_7 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 454.0
HKD1_k127_6288638_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 417.0
HKD1_k127_6288638_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 354.0
HKD1_k127_6307283_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.389e-273 880.0
HKD1_k127_6307283_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 441.0
HKD1_k127_6307283_10 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000001548 140.0
HKD1_k127_6307283_11 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000004009 93.0
HKD1_k127_6307283_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.00000052 57.0
HKD1_k127_6307283_2 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 434.0
HKD1_k127_6307283_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 396.0
HKD1_k127_6307283_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005429 279.0
HKD1_k127_6307283_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008321 291.0
HKD1_k127_6307283_6 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000007195 228.0
HKD1_k127_6307283_7 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000006387 206.0
HKD1_k127_6307283_8 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000232 158.0
HKD1_k127_6307283_9 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000007425 138.0
HKD1_k127_6313301_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 554.0
HKD1_k127_6313301_1 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 406.0
HKD1_k127_6313301_2 protein conserved in bacteria K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 402.0
HKD1_k127_6313301_3 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 356.0
HKD1_k127_6313301_4 Pfam L-fucose isomerase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 324.0
HKD1_k127_6313301_5 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000224 186.0
HKD1_k127_6313301_6 Large extracellular alpha-helical protein K20276 - - 0.00000000000000000000000000000000000000005448 164.0
HKD1_k127_6313301_7 Hfq protein - - - 0.00000000000000000000000000007052 127.0
HKD1_k127_6313301_8 peptidase inhibitor activity - - - 0.00000000000000004881 94.0
HKD1_k127_6362247_0 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 368.0
HKD1_k127_6362247_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 353.0
HKD1_k127_6362247_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000001099 199.0
HKD1_k127_6371959_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 466.0
HKD1_k127_6371959_1 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 341.0
HKD1_k127_6371959_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000008182 246.0
HKD1_k127_6371959_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000002682 150.0
HKD1_k127_6371959_4 Iodothyronine deiodinase - - - 0.00000000000000000000000000001341 122.0
HKD1_k127_6371959_6 Periplasmic copper-binding protein (NosD) - - - 0.000000001926 71.0
HKD1_k127_6371959_7 Predicted membrane protein (DUF2127) - - - 0.0000001918 61.0
HKD1_k127_6371959_9 Iodothyronine deiodinase - - - 0.000611 46.0
HKD1_k127_6378926_0 Sulfatase K01130 - 3.1.6.1 5.02e-284 880.0
HKD1_k127_6378926_1 PFAM SMP-30 Gluconolaconase - - - 4.733e-274 848.0
HKD1_k127_6378926_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 374.0
HKD1_k127_6378926_11 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 314.0
HKD1_k127_6378926_12 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001831 273.0
HKD1_k127_6378926_13 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000003858 263.0
HKD1_k127_6378926_14 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005227 242.0
HKD1_k127_6378926_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000134 252.0
HKD1_k127_6378926_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000002841 254.0
HKD1_k127_6378926_17 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000006707 252.0
HKD1_k127_6378926_18 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000006335 239.0
HKD1_k127_6378926_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000000000000000004187 209.0
HKD1_k127_6378926_2 Sulfatase K01130 - 3.1.6.1 1.789e-261 812.0
HKD1_k127_6378926_20 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000001774 223.0
HKD1_k127_6378926_21 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000886 196.0
HKD1_k127_6378926_22 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000003298 184.0
HKD1_k127_6378926_23 UPF0126 domain - - - 0.000000000000000000000000000000000000000000003896 177.0
HKD1_k127_6378926_24 - - - - 0.000000000000000000001561 99.0
HKD1_k127_6378926_25 B3/4 domain - - - 0.00000000000000000002752 92.0
HKD1_k127_6378926_26 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000108 87.0
HKD1_k127_6378926_27 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000001961 72.0
HKD1_k127_6378926_28 Pfam:DUF422 - - - 0.00000007276 63.0
HKD1_k127_6378926_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.683e-213 693.0
HKD1_k127_6378926_4 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.789e-207 664.0
HKD1_k127_6378926_5 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 620.0
HKD1_k127_6378926_6 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 615.0
HKD1_k127_6378926_7 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 434.0
HKD1_k127_6378926_8 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 413.0
HKD1_k127_6378926_9 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 395.0
HKD1_k127_6388327_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 3.026e-222 696.0
HKD1_k127_6388327_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 614.0
HKD1_k127_6388327_10 KR domain K07535 - - 0.000000000000000000000000000000000000000000007338 186.0
HKD1_k127_6388327_11 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000003128 168.0
HKD1_k127_6388327_12 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000005345 158.0
HKD1_k127_6388327_13 - - - - 0.00000000000000000000000000000000004716 144.0
HKD1_k127_6388327_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000004019 117.0
HKD1_k127_6388327_15 Putative esterase - - - 0.000000000000000000000000005948 124.0
HKD1_k127_6388327_16 - - - - 0.00001459 53.0
HKD1_k127_6388327_2 PFAM Major facilitator superfamily K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 537.0
HKD1_k127_6388327_3 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 437.0
HKD1_k127_6388327_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 387.0
HKD1_k127_6388327_5 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002183 277.0
HKD1_k127_6388327_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000002084 242.0
HKD1_k127_6388327_7 - - - - 0.00000000000000000000000000000000000000000000000000001473 196.0
HKD1_k127_6388327_8 cytochrome c nitrite reductase K15876 - - 0.00000000000000000000000000000000000000000000005172 189.0
HKD1_k127_6388327_9 PFAM ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000008924 186.0
HKD1_k127_6444048_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 430.0
HKD1_k127_6444048_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
HKD1_k127_6444048_2 - - - - 0.0000000000000000000000000000002482 128.0
HKD1_k127_6444048_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000002399 119.0
HKD1_k127_6444048_4 TIGRFAM DNA binding domain protein, excisionase family - - - 0.000000005918 61.0
HKD1_k127_6444048_5 TIGRFAM DNA binding domain protein, excisionase family - - - 0.000005323 51.0
HKD1_k127_6530716_0 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 414.0
HKD1_k127_6530716_1 PAS domain containing protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 376.0
HKD1_k127_6553454_0 OmpA family K03640 - - 0.000000000000000000000000000000000004519 143.0
HKD1_k127_6553454_1 AhpC/TSA family - - - 0.00000000000000000000000000000000004757 147.0
HKD1_k127_6553454_2 lactoylglutathione lyase activity - - - 0.0000000000000000000000000003768 123.0
HKD1_k127_6553454_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000001206 115.0
HKD1_k127_6553454_4 Regulatory protein MarR - - - 0.000000000000000000000000638 114.0
HKD1_k127_6553454_5 Alpha/beta hydrolase family - - - 0.00000000000000000004427 91.0
HKD1_k127_6553454_6 Transcription factor zinc-finger K09981 - - 0.0008628 49.0
HKD1_k127_6610076_0 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 355.0
HKD1_k127_6610076_1 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.0000000000000000000000000000000000000000000024 168.0
HKD1_k127_6610076_2 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000453 173.0
HKD1_k127_6616073_0 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 312.0
HKD1_k127_6616073_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000009167 145.0
HKD1_k127_6616073_2 Forkhead associated domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.000000000001003 72.0
HKD1_k127_6619217_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 427.0
HKD1_k127_6619217_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000003071 187.0
HKD1_k127_6619217_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000004132 187.0
HKD1_k127_6687944_0 Protein kinase domain K12132 - 2.7.11.1 6.502e-218 707.0
HKD1_k127_6687944_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 503.0
HKD1_k127_6687944_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 411.0
HKD1_k127_6687944_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 349.0
HKD1_k127_6687944_4 HEPN domain - - - 0.0000000000000000000000001954 114.0
HKD1_k127_6788752_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 585.0
HKD1_k127_6788752_1 Oligopeptide transporter OPT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006357 250.0
HKD1_k127_6791180_0 TIGRFAM FeS assembly protein SufB K09014 - - 1.489e-228 712.0
HKD1_k127_6791180_1 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 307.0
HKD1_k127_6791180_2 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001399 284.0
HKD1_k127_6840997_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 473.0
HKD1_k127_6840997_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 467.0
HKD1_k127_6840997_10 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000008897 188.0
HKD1_k127_6840997_11 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000002139 179.0
HKD1_k127_6840997_12 - - - - 0.0000000000000000000000000000000000000000237 168.0
HKD1_k127_6840997_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001484 106.0
HKD1_k127_6840997_14 metallopeptidase activity - - - 0.0000007885 61.0
HKD1_k127_6840997_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 419.0
HKD1_k127_6840997_3 polysaccharide catabolic process K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 356.0
HKD1_k127_6840997_4 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 350.0
HKD1_k127_6840997_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 314.0
HKD1_k127_6840997_6 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 306.0
HKD1_k127_6840997_7 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 297.0
HKD1_k127_6840997_8 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004635 296.0
HKD1_k127_6840997_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000005045 240.0
HKD1_k127_700763_0 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 441.0
HKD1_k127_700763_1 Sulfate ABC transporter substrate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000001484 199.0
HKD1_k127_700763_2 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000003922 198.0
HKD1_k127_700763_3 TRANSCRIPTIONal - - - 0.00000000000000000000000000000003983 127.0
HKD1_k127_700763_4 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000008465 123.0
HKD1_k127_700763_5 PFAM Lytic transglycosylase catalytic K08309 - - 0.00002578 47.0
HKD1_k127_7054606_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1089.0
HKD1_k127_7054606_1 PFAM Na-Ca exchanger integrin-beta4 - - - 1.115e-210 717.0
HKD1_k127_7054606_10 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
HKD1_k127_7054606_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000003922 238.0
HKD1_k127_7054606_12 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000000000001321 201.0
HKD1_k127_7054606_13 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000007216 197.0
HKD1_k127_7054606_14 PFAM ABC-2 type transporter K01992,K09690 - - 0.00000000000000000000000000000000000000000000007438 179.0
HKD1_k127_7054606_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000003209 162.0
HKD1_k127_7054606_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002539 157.0
HKD1_k127_7054606_17 EamA-like transporter family - - - 0.0000000000000000000000000000000664 141.0
HKD1_k127_7054606_18 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000002152 114.0
HKD1_k127_7054606_19 Glycosyltransferase family 87 - - - 0.00000000000000000000008694 115.0
HKD1_k127_7054606_2 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 3.134e-201 657.0
HKD1_k127_7054606_20 Metallo-peptidase family M12 - - - 0.000000000000000001452 103.0
HKD1_k127_7054606_21 Protein conserved in bacteria - - - 0.00000000005943 76.0
HKD1_k127_7054606_3 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 531.0
HKD1_k127_7054606_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 439.0
HKD1_k127_7054606_5 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 386.0
HKD1_k127_7054606_6 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 370.0
HKD1_k127_7054606_7 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 341.0
HKD1_k127_7054606_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 313.0
HKD1_k127_7054606_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 295.0
HKD1_k127_7055107_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 537.0
HKD1_k127_7055107_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 451.0
HKD1_k127_7055107_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001068 215.0
HKD1_k127_7055107_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000001317 134.0
HKD1_k127_7055107_4 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.00000000000000942 82.0
HKD1_k127_7065088_0 Sulfate permease family - - - 6.911e-228 721.0
HKD1_k127_7065088_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.591e-196 628.0
HKD1_k127_7065088_11 - - - - 0.000000000000000000005151 100.0
HKD1_k127_7065088_12 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000003523 57.0
HKD1_k127_7065088_2 Predicted Permease Membrane Region K07085 - - 3.229e-195 646.0
HKD1_k127_7065088_3 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 508.0
HKD1_k127_7065088_4 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 458.0
HKD1_k127_7065088_5 COG NOG10142 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 441.0
HKD1_k127_7065088_6 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 445.0
HKD1_k127_7065088_7 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 420.0
HKD1_k127_7065088_8 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
HKD1_k127_7065088_9 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005369 276.0
HKD1_k127_7074915_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1140.0
HKD1_k127_7074915_1 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 5.808e-288 909.0
HKD1_k127_7074915_10 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000000002051 163.0
HKD1_k127_7074915_11 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000004682 154.0
HKD1_k127_7074915_12 - - - - 0.00000000000000000000000000000000000000007899 157.0
HKD1_k127_7074915_13 glyoxalase III activity - - - 0.0000000000000000000000000000000000000005171 158.0
HKD1_k127_7074915_14 DinB family - - - 0.00000000000000000000000000000000000001169 154.0
HKD1_k127_7074915_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000013 142.0
HKD1_k127_7074915_17 FecR protein - - - 0.000003048 59.0
HKD1_k127_7074915_18 - - - - 0.0003034 46.0
HKD1_k127_7074915_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 569.0
HKD1_k127_7074915_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 497.0
HKD1_k127_7074915_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 392.0
HKD1_k127_7074915_5 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 383.0
HKD1_k127_7074915_6 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003556 257.0
HKD1_k127_7074915_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000003002 256.0
HKD1_k127_7074915_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000335 231.0
HKD1_k127_7074915_9 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000227 170.0
HKD1_k127_7082024_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 6.332e-227 732.0
HKD1_k127_7082024_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 555.0
HKD1_k127_7082024_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000006948 209.0
HKD1_k127_7082024_3 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000005777 212.0
HKD1_k127_7082024_4 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000001873 151.0
HKD1_k127_7082024_5 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000002734 65.0
HKD1_k127_7082024_6 Domain of unknown function (DUF4136) - - - 0.00000000006074 72.0
HKD1_k127_7082024_7 DinB family - - - 0.0000004963 58.0
HKD1_k127_7082024_8 Periplasmic component of the Tol biopolymer transport system - - - 0.000009186 53.0
HKD1_k127_7082024_9 Domain of unknown function (DUF4136) - - - 0.00007517 55.0
HKD1_k127_7084362_0 peptidase K07386 - - 6.992e-251 796.0
HKD1_k127_7084362_1 Endoribonuclease L-PSP - - - 7.108e-214 676.0
HKD1_k127_7084362_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 587.0
HKD1_k127_7084362_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.0000000000000000000000000000000000000001973 168.0
HKD1_k127_7084362_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000003027 60.0
HKD1_k127_7084488_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 3.258e-216 683.0
HKD1_k127_7084488_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 386.0
HKD1_k127_7084488_2 wide pore channel activity K07267 - - 0.000000000000000000000000000000000000001069 164.0
HKD1_k127_7089420_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 599.0
HKD1_k127_7089420_1 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 336.0
HKD1_k127_7089420_2 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 290.0
HKD1_k127_7089420_3 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001576 251.0
HKD1_k127_7089420_4 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000007587 249.0
HKD1_k127_7089420_5 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000001342 118.0
HKD1_k127_7089420_6 IMP dehydrogenase activity - - - 0.0000000000000005238 85.0
HKD1_k127_7089420_7 Cbs domain K04767 - - 0.0000000000000006815 84.0
HKD1_k127_7089420_8 Family of unknown function (DUF5335) - - - 0.00000006055 64.0
HKD1_k127_7100153_0 Amino acid permease - - - 0.00000000000000000000000000000000000000004389 166.0
HKD1_k127_7115469_1 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
HKD1_k127_7115469_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000003728 269.0
HKD1_k127_7115469_3 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000001075 164.0
HKD1_k127_7116266_0 L-Lactate permease K03303 - - 1.166e-301 937.0
HKD1_k127_7116266_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.409e-275 869.0
HKD1_k127_7116266_10 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 560.0
HKD1_k127_7116266_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 508.0
HKD1_k127_7116266_12 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 488.0
HKD1_k127_7116266_13 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 482.0
HKD1_k127_7116266_14 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 504.0
HKD1_k127_7116266_15 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 494.0
HKD1_k127_7116266_16 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 480.0
HKD1_k127_7116266_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 438.0
HKD1_k127_7116266_18 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 458.0
HKD1_k127_7116266_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 436.0
HKD1_k127_7116266_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.002e-237 754.0
HKD1_k127_7116266_20 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 449.0
HKD1_k127_7116266_21 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 437.0
HKD1_k127_7116266_22 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 420.0
HKD1_k127_7116266_23 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 436.0
HKD1_k127_7116266_24 phosphoserine phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 434.0
HKD1_k127_7116266_25 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 404.0
HKD1_k127_7116266_26 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 421.0
HKD1_k127_7116266_27 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 389.0
HKD1_k127_7116266_28 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 363.0
HKD1_k127_7116266_29 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 383.0
HKD1_k127_7116266_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.25e-237 740.0
HKD1_k127_7116266_30 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 344.0
HKD1_k127_7116266_31 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 361.0
HKD1_k127_7116266_32 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 345.0
HKD1_k127_7116266_33 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 335.0
HKD1_k127_7116266_34 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 334.0
HKD1_k127_7116266_35 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 346.0
HKD1_k127_7116266_36 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 316.0
HKD1_k127_7116266_37 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001655 297.0
HKD1_k127_7116266_38 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006075 296.0
HKD1_k127_7116266_39 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004531 299.0
HKD1_k127_7116266_4 Malate synthase K01638 - 2.3.3.9 1.326e-235 739.0
HKD1_k127_7116266_40 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000959 281.0
HKD1_k127_7116266_41 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001475 280.0
HKD1_k127_7116266_42 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002172 263.0
HKD1_k127_7116266_43 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
HKD1_k127_7116266_44 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000004173 260.0
HKD1_k127_7116266_45 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004242 249.0
HKD1_k127_7116266_46 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003759 244.0
HKD1_k127_7116266_47 MoeZ MoeB domain K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000002835 252.0
HKD1_k127_7116266_48 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004989 235.0
HKD1_k127_7116266_49 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001008 227.0
HKD1_k127_7116266_5 Voltage gated chloride channel - - - 3.381e-218 692.0
HKD1_k127_7116266_50 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000827 209.0
HKD1_k127_7116266_51 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000001676 209.0
HKD1_k127_7116266_52 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000007883 201.0
HKD1_k127_7116266_53 Metal-dependent phosphoesterase K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000001579 195.0
HKD1_k127_7116266_54 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000005289 203.0
HKD1_k127_7116266_55 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000002418 190.0
HKD1_k127_7116266_56 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000002783 184.0
HKD1_k127_7116266_57 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000005752 162.0
HKD1_k127_7116266_58 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000007142 138.0
HKD1_k127_7116266_59 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000002472 133.0
HKD1_k127_7116266_6 Elongation factor G, domain IV K02355 - - 1.843e-206 662.0
HKD1_k127_7116266_60 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000002887 146.0
HKD1_k127_7116266_61 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000488 132.0
HKD1_k127_7116266_62 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000001628 138.0
HKD1_k127_7116266_64 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000548 122.0
HKD1_k127_7116266_65 Winged helix DNA-binding domain - - - 0.00000000000000000000008188 108.0
HKD1_k127_7116266_66 Peptidase MA superfamily - - - 0.00000000000000001431 99.0
HKD1_k127_7116266_67 DNA-binding transcription factor activity - - - 0.00000000000003227 80.0
HKD1_k127_7116266_68 Protein of unknown function (DUF2662) - - - 0.0000000000006657 78.0
HKD1_k127_7116266_69 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.000000000007323 78.0
HKD1_k127_7116266_7 Alpha/beta hydrolase family - - - 1.622e-195 631.0
HKD1_k127_7116266_71 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000001016 66.0
HKD1_k127_7116266_72 VanZ like family - - - 0.0000003721 61.0
HKD1_k127_7116266_73 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000004165 51.0
HKD1_k127_7116266_75 Tetratricopeptide repeat - - - 0.000009268 59.0
HKD1_k127_7116266_77 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0001219 48.0
HKD1_k127_7116266_78 - - - - 0.0005261 46.0
HKD1_k127_7116266_79 Thioredoxin-like - - - 0.0005669 51.0
HKD1_k127_7116266_8 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 549.0
HKD1_k127_7116266_9 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 536.0
HKD1_k127_7130288_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 552.0
HKD1_k127_7130288_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 548.0
HKD1_k127_7130288_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 476.0
HKD1_k127_7130288_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 346.0
HKD1_k127_7130288_4 ABC transporter, ATP-binding protein - - - 0.000000000000000000000000000000000252 139.0
HKD1_k127_7141777_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 366.0
HKD1_k127_7141777_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000607 219.0
HKD1_k127_7141777_2 copper resistance - - - 0.000000000000000000000000000000000000000000000000003549 197.0
HKD1_k127_7141777_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.000000000000000000000000000000000000000000000001289 175.0
HKD1_k127_7170983_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 522.0
HKD1_k127_7170983_1 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 424.0
HKD1_k127_7170983_2 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 399.0
HKD1_k127_7170983_3 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000007368 202.0
HKD1_k127_7170983_4 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000007772 117.0
HKD1_k127_7170983_5 Protein conserved in bacteria - - - 0.0000000000000000000000000007951 124.0
HKD1_k127_7170983_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0003772 48.0
HKD1_k127_7183360_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 359.0
HKD1_k127_7183360_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 308.0
HKD1_k127_7183360_10 general secretion pathway protein K02456,K02650 - - 0.00000004336 65.0
HKD1_k127_7183360_2 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 324.0
HKD1_k127_7183360_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000004236 197.0
HKD1_k127_7183360_4 domain protein K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000004467 193.0
HKD1_k127_7183360_5 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.0000000000000000000000000000000000000000000000000163 198.0
HKD1_k127_7183360_6 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000004615 178.0
HKD1_k127_7183360_7 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000004102 170.0
HKD1_k127_7183360_8 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000004991 130.0
HKD1_k127_7183360_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.0000000000001568 81.0
HKD1_k127_7200600_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 475.0
HKD1_k127_7200600_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000001825 206.0
HKD1_k127_7200600_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000001921 214.0
HKD1_k127_7253908_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.708e-232 747.0
HKD1_k127_7253908_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 621.0
HKD1_k127_7253908_2 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000112 157.0
HKD1_k127_7253908_3 PIN domain - - - 0.000000000000000000000000007163 117.0
HKD1_k127_7253908_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000165 103.0
HKD1_k127_7253908_5 SpoVT / AbrB like domain - - - 0.00000000000001833 75.0
HKD1_k127_7281226_0 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 426.0
HKD1_k127_7281226_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 421.0
HKD1_k127_7281226_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 395.0
HKD1_k127_7281226_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000305 282.0
HKD1_k127_7281226_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001764 282.0
HKD1_k127_7281226_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001618 277.0
HKD1_k127_7281226_6 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002683 245.0
HKD1_k127_7281226_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000005391 194.0
HKD1_k127_7281226_8 - - - - 0.0000000000000000000000006895 112.0
HKD1_k127_7281226_9 - - - - 0.00000000000000000000002287 109.0
HKD1_k127_7282748_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 6.613e-275 859.0
HKD1_k127_7282748_1 Transcriptional regulator with HTH domain and aminotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 381.0
HKD1_k127_7282748_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 352.0
HKD1_k127_7282748_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 318.0
HKD1_k127_7282748_4 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000215 256.0
HKD1_k127_7282748_5 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000006132 198.0
HKD1_k127_7282748_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000001544 90.0
HKD1_k127_7282748_7 response regulator - - - 0.00000000000004167 81.0
HKD1_k127_7282748_8 Serine/Threonine protein kinases, catalytic domain K08884,K12132 - 2.7.11.1 0.000000001176 72.0
HKD1_k127_7282748_9 Domain of Unknown Function (DUF1206) - - - 0.000006193 57.0
HKD1_k127_7305872_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 374.0
HKD1_k127_7305872_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000001365 197.0
HKD1_k127_7305872_2 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.0000000002282 74.0
HKD1_k127_7305872_3 COG0642 Signal transduction histidine kinase - - - 0.0002769 49.0
HKD1_k127_7312078_0 oligopeptide transporter, OPT family - - - 6.179e-216 690.0
HKD1_k127_7312078_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 583.0
HKD1_k127_7312078_10 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000006578 165.0
HKD1_k127_7312078_11 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000005701 143.0
HKD1_k127_7312078_12 - - - - 0.00000000000000000000000000000000001232 145.0
HKD1_k127_7312078_13 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000009089 151.0
HKD1_k127_7312078_14 - - - - 0.000000000000000000000000000000767 138.0
HKD1_k127_7312078_15 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000006721 105.0
HKD1_k127_7312078_16 - - - - 0.000000000000000000005264 97.0
HKD1_k127_7312078_17 Domain of unknown function (DUF4437) - - - 0.000000000000000001815 93.0
HKD1_k127_7312078_19 - - - - 0.000007344 53.0
HKD1_k127_7312078_2 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 480.0
HKD1_k127_7312078_20 Glutaredoxin K03676 - - 0.00001476 48.0
HKD1_k127_7312078_21 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000443 52.0
HKD1_k127_7312078_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 431.0
HKD1_k127_7312078_4 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 422.0
HKD1_k127_7312078_5 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 378.0
HKD1_k127_7312078_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 324.0
HKD1_k127_7312078_7 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001382 277.0
HKD1_k127_7312078_8 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000001138 214.0
HKD1_k127_7312078_9 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000002378 188.0
HKD1_k127_7403754_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1135.0
HKD1_k127_7403754_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.252e-287 901.0
HKD1_k127_7403754_10 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001157 290.0
HKD1_k127_7403754_11 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000003018 227.0
HKD1_k127_7403754_12 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000009685 211.0
HKD1_k127_7403754_13 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000005137 175.0
HKD1_k127_7403754_14 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000003937 161.0
HKD1_k127_7403754_15 - K01992,K19341 - - 0.00000000000000000000000000000003495 141.0
HKD1_k127_7403754_16 carbon dioxide binding K04653,K04654 - - 0.000000000000000000000000008354 116.0
HKD1_k127_7403754_17 Biogenesis protein - - - 0.000000000000000000000001211 120.0
HKD1_k127_7403754_18 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0000000000000002933 89.0
HKD1_k127_7403754_19 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000007536 87.0
HKD1_k127_7403754_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.157e-282 877.0
HKD1_k127_7403754_20 Peptidase family S58 - - - 0.000000000000002635 77.0
HKD1_k127_7403754_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.00000000008419 75.0
HKD1_k127_7403754_22 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000002409 61.0
HKD1_k127_7403754_23 - - - - 0.0003269 53.0
HKD1_k127_7403754_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K21624 - 4.2.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 554.0
HKD1_k127_7403754_4 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 511.0
HKD1_k127_7403754_5 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 495.0
HKD1_k127_7403754_6 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 486.0
HKD1_k127_7403754_7 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 364.0
HKD1_k127_7403754_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 327.0
HKD1_k127_7403754_9 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 319.0
HKD1_k127_7426647_0 Major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 610.0
HKD1_k127_7426647_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 602.0
HKD1_k127_7426647_10 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000005106 125.0
HKD1_k127_7426647_11 heme oxygenase (decyclizing) activity - - - 0.000000000000000006676 98.0
HKD1_k127_7426647_12 - - - - 0.000000000000000006789 87.0
HKD1_k127_7426647_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 492.0
HKD1_k127_7426647_3 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 457.0
HKD1_k127_7426647_4 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 354.0
HKD1_k127_7426647_5 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 294.0
HKD1_k127_7426647_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002094 269.0
HKD1_k127_7426647_7 L-Asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001682 258.0
HKD1_k127_7426647_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000009772 182.0
HKD1_k127_7426647_9 Outer membrane efflux protein - - - 0.000000000000000000000000000001036 138.0
HKD1_k127_74341_0 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 421.0
HKD1_k127_74341_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 449.0
HKD1_k127_74341_10 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000004462 182.0
HKD1_k127_74341_11 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000002633 151.0
HKD1_k127_74341_12 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000001788 124.0
HKD1_k127_74341_13 Phosphate-selective porin O and P - - - 0.0000000000000000000000001642 123.0
HKD1_k127_74341_14 CHAD - - - 0.0000000000008301 79.0
HKD1_k127_74341_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 411.0
HKD1_k127_74341_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 373.0
HKD1_k127_74341_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 341.0
HKD1_k127_74341_5 catalyzes the methylation of cytosine at position 1962 of the 23S rRNA K06969 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 305.0
HKD1_k127_74341_6 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006987 298.0
HKD1_k127_74341_7 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004361 271.0
HKD1_k127_74341_8 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000002615 213.0
HKD1_k127_74341_9 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000008584 224.0
HKD1_k127_7444883_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 438.0
HKD1_k127_7444883_1 oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 310.0
HKD1_k127_7444883_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005909 301.0
HKD1_k127_7444883_3 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000007681 228.0
HKD1_k127_7444883_4 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000925 188.0
HKD1_k127_7444883_5 NUDIX domain - - - 0.00000000000000000000000000000000001786 141.0
HKD1_k127_7444883_6 Transport permease protein - - - 0.0000000000000000000000000000006851 141.0
HKD1_k127_7444883_7 recA bacterial DNA recombination protein - - - 0.0000001252 58.0
HKD1_k127_7453478_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000002421 204.0
HKD1_k127_7453478_1 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000009033 160.0
HKD1_k127_7478582_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1504.0
HKD1_k127_7478582_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1388.0
HKD1_k127_7478582_10 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000003159 248.0
HKD1_k127_7478582_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001351 225.0
HKD1_k127_7478582_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000001084 205.0
HKD1_k127_7478582_13 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000002212 206.0
HKD1_k127_7478582_14 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000007958 191.0
HKD1_k127_7478582_16 YMGG-like Gly-zipper - - - 0.00000000000000000000000003568 118.0
HKD1_k127_7478582_17 Chromate resistance exported protein - - - 0.000000000000000000001554 112.0
HKD1_k127_7478582_18 - - - - 0.000000000000000001547 87.0
HKD1_k127_7478582_19 Copper binding proteins, plastocyanin/azurin family - - - 0.00000001443 63.0
HKD1_k127_7478582_2 Belongs to the peptidase M16 family K07263 - - 0.0 1146.0
HKD1_k127_7478582_20 FeoA K04758 - - 0.0004326 53.0
HKD1_k127_7478582_3 cellulose binding - - - 2.428e-266 854.0
HKD1_k127_7478582_4 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.86e-254 802.0
HKD1_k127_7478582_5 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.037e-209 671.0
HKD1_k127_7478582_6 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 486.0
HKD1_k127_7478582_7 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 487.0
HKD1_k127_7478582_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 398.0
HKD1_k127_7478582_9 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006931 262.0
HKD1_k127_7523180_0 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000000000000000000000000000000000004168 209.0
HKD1_k127_7523180_1 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000008808 135.0
HKD1_k127_754343_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 312.0
HKD1_k127_754343_1 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003693 297.0
HKD1_k127_754343_2 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001913 283.0
HKD1_k127_754343_3 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
HKD1_k127_754343_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000002261 156.0
HKD1_k127_754343_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000001081 122.0
HKD1_k127_7547365_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 455.0
HKD1_k127_7547365_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 355.0
HKD1_k127_7547365_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 350.0
HKD1_k127_7547365_3 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
HKD1_k127_7547365_4 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 321.0
HKD1_k127_7547365_5 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 317.0
HKD1_k127_7547365_6 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004667 279.0
HKD1_k127_7547365_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000001781 132.0
HKD1_k127_7547365_8 - - - - 0.0000000006938 68.0
HKD1_k127_7547365_9 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000004148 57.0
HKD1_k127_7552892_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 7.348e-206 665.0
HKD1_k127_7552892_1 Peptidase, M20 K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 351.0
HKD1_k127_7552892_10 Methyltransferase FkbM domain - - - 0.0000000000000000000000000001421 133.0
HKD1_k127_7552892_11 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000008923 128.0
HKD1_k127_7552892_12 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000001181 100.0
HKD1_k127_7552892_13 PFAM Transcriptional regulator - - - 0.000000000005649 73.0
HKD1_k127_7552892_14 Domain of unknown function (DUF4149) - - - 0.00000665 59.0
HKD1_k127_7552892_15 - - - - 0.0001453 51.0
HKD1_k127_7552892_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
HKD1_k127_7552892_3 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 291.0
HKD1_k127_7552892_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000024 269.0
HKD1_k127_7552892_5 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000008895 261.0
HKD1_k127_7552892_6 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000009081 206.0
HKD1_k127_7552892_7 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000006576 206.0
HKD1_k127_7552892_8 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001496 205.0
HKD1_k127_7552892_9 Transglutaminase-like superfamily - - - 0.000000000000000000000000000007299 136.0
HKD1_k127_7571871_0 Involved in the tonB-independent uptake of proteins - - - 2.391e-225 725.0
HKD1_k127_7571871_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002237 272.0
HKD1_k127_7571871_2 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0001452 53.0
HKD1_k127_7627568_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 573.0
HKD1_k127_7627568_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000001777 183.0
HKD1_k127_7649257_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.747e-198 621.0
HKD1_k127_7649257_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 421.0
HKD1_k127_7649257_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 302.0
HKD1_k127_7649257_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
HKD1_k127_7649257_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000001676 177.0
HKD1_k127_7649257_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000609 151.0
HKD1_k127_7649257_6 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001545 166.0
HKD1_k127_7649257_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002485 114.0
HKD1_k127_7649257_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000686 103.0
HKD1_k127_7686836_0 Protein of unknown function (DUF3604) - - - 2.705e-317 989.0
HKD1_k127_7686836_1 Protein of unknown function (DUF3604) - - - 5.624e-195 623.0
HKD1_k127_7686836_2 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 331.0
HKD1_k127_7686836_3 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 319.0
HKD1_k127_7686836_4 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007215 239.0
HKD1_k127_7686836_5 - - - - 0.00000000000000000002095 105.0
HKD1_k127_7729599_0 MacB-like periplasmic core domain - - - 1.199e-278 881.0
HKD1_k127_7729599_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 4.119e-240 763.0
HKD1_k127_7729599_10 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000001895 254.0
HKD1_k127_7729599_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000004776 249.0
HKD1_k127_7729599_12 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000003058 210.0
HKD1_k127_7729599_13 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000007503 214.0
HKD1_k127_7729599_14 - - - - 0.000000000000000000000000000000000000000000000000006816 185.0
HKD1_k127_7729599_15 YceI-like domain - - - 0.00000000000000000000000000000000000000000000001156 178.0
HKD1_k127_7729599_16 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000004687 157.0
HKD1_k127_7729599_17 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000001336 171.0
HKD1_k127_7729599_18 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000005273 148.0
HKD1_k127_7729599_19 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000003396 143.0
HKD1_k127_7729599_2 Belongs to the aldehyde dehydrogenase family K00128,K00138,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 604.0
HKD1_k127_7729599_20 DinB superfamily - - - 0.000000000000000000000000000000001135 137.0
HKD1_k127_7729599_21 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000004089 139.0
HKD1_k127_7729599_22 DinB superfamily - - - 0.0000000000000000000000000000001276 140.0
HKD1_k127_7729599_23 DinB family - - - 0.0000000000000000000000000000004652 130.0
HKD1_k127_7729599_24 - - - - 0.0000000000000000000000002323 115.0
HKD1_k127_7729599_25 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000000006068 104.0
HKD1_k127_7729599_26 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000006334 72.0
HKD1_k127_7729599_27 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0001488 53.0
HKD1_k127_7729599_3 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 468.0
HKD1_k127_7729599_4 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 464.0
HKD1_k127_7729599_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 485.0
HKD1_k127_7729599_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 421.0
HKD1_k127_7729599_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 424.0
HKD1_k127_7729599_8 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 401.0
HKD1_k127_7729599_9 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 354.0
HKD1_k127_7731738_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 613.0
HKD1_k127_7731738_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002299 266.0
HKD1_k127_7731738_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
HKD1_k127_7731738_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001066 228.0
HKD1_k127_7731738_4 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000003005 196.0
HKD1_k127_7731738_5 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.0000000000000000000000000000000000000000000001524 181.0
HKD1_k127_7731738_6 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000005058 152.0
HKD1_k127_7731738_7 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000003686 119.0
HKD1_k127_7731738_8 - - - - 0.0000000000000000000001427 109.0
HKD1_k127_7731738_9 acetyltransferase - - - 0.0000000000001543 80.0
HKD1_k127_7853_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 426.0
HKD1_k127_7853_1 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003306 263.0
HKD1_k127_7853_2 COG0438 Glycosyltransferase K07011 - - 0.00000000000000000000000000000000000000000000003346 191.0
HKD1_k127_7853_3 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000004342 171.0
HKD1_k127_7853_5 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000144 132.0
HKD1_k127_7853_6 Calcineurin-like phosphoesterase - - - 0.00000000000000000006836 106.0
HKD1_k127_7853_7 Protein of unknown function (DUF3309) - - - 0.00000000000000004649 83.0
HKD1_k127_7853_8 - - - - 0.000000002116 69.0
HKD1_k127_7853_9 Outer membrane protein beta-barrel domain K16079 - - 0.000005453 57.0
HKD1_k127_832219_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 468.0
HKD1_k127_832219_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 398.0
HKD1_k127_832219_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 321.0
HKD1_k127_832219_3 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 301.0
HKD1_k127_832219_4 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000002296 133.0
HKD1_k127_832219_5 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001004 115.0
HKD1_k127_832219_6 Phosphoribosyl transferase domain - - - 0.000000000000000000000009068 111.0
HKD1_k127_832219_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000009374 59.0
HKD1_k127_98722_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1026.0