logo

Overview

ID MAG01760
Name HKD1_bin.8
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Versatilivoradales
Family Versatilivoraceae
Genus
Species
Assembly information
Completeness (%) 90.22
Contamination (%) 5.41
GC content (%) 50.0
N50 (bp) 7,581
Genome size (bp) 4,937,167

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4043

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1001394_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 2.346e-300 931.0
HKD1_k127_1001394_1 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 324.0
HKD1_k127_1001394_2 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001214 261.0
HKD1_k127_1036490_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1013.0
HKD1_k127_1036490_1 HlyD family secretion protein K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 287.0
HKD1_k127_1060218_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.265e-218 687.0
HKD1_k127_1060218_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 416.0
HKD1_k127_1060218_2 Periplasmic substrate-binding component of the ATP-dependent ribose transport system K10439 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.00000000000000005235 86.0
HKD1_k127_1074492_0 Amidohydrolase family K06015 - 3.5.1.81 1.291e-224 707.0
HKD1_k127_1074492_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 409.0
HKD1_k127_1074492_2 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007038 246.0
HKD1_k127_1075027_0 COG0339 Zn-dependent oligopeptidases K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 3.833e-294 914.0
HKD1_k127_1075027_1 -O-antigen K02847,K18814 - - 0.00000000000000000000000000000000000007199 157.0
HKD1_k127_1079594_0 Cytochrome c - - - 1.495e-318 997.0
HKD1_k127_1079594_1 Protein of unknown function (DUF1501) - - - 4.019e-214 675.0
HKD1_k127_1079594_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 589.0
HKD1_k127_1079594_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 292.0
HKD1_k127_1079594_4 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000001868 109.0
HKD1_k127_1079594_5 - - - - 0.000000000001122 81.0
HKD1_k127_1084280_0 COG COG0383 Alpha-mannosidase - - - 0.0000000000000000000000000000000000000000000000005464 201.0
HKD1_k127_1084280_1 PA14 domain - - - 0.0000000006599 73.0
HKD1_k127_1086328_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000003606 238.0
HKD1_k127_108963_0 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000002073 101.0
HKD1_k127_108963_1 TadE-like protein - - - 0.00000000000000000106 92.0
HKD1_k127_108963_2 TadE-like protein - - - 0.000000000000007227 81.0
HKD1_k127_1093820_0 AMP-binding enzyme K00666,K12423,K12426,K12428 - - 1.845e-205 670.0
HKD1_k127_1102298_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 634.0
HKD1_k127_1102298_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006391 279.0
HKD1_k127_1102298_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000007131 221.0
HKD1_k127_1112325_0 Bacterial regulatory protein, Fis family - - - 3.503e-244 771.0
HKD1_k127_1112325_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000002839 82.0
HKD1_k127_1114349_0 UvrD/REP helicase N-terminal domain K03582,K16898 - 3.1.11.5,3.6.4.12 8.59e-242 781.0
HKD1_k127_1114349_1 Viral (Superfamily 1) RNA helicase K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 521.0
HKD1_k127_1114349_2 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001135 254.0
HKD1_k127_1114349_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000007272 230.0
HKD1_k127_1114349_4 - - - - 0.000000000000000000004939 96.0
HKD1_k127_1121035_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 421.0
HKD1_k127_1121035_1 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 372.0
HKD1_k127_1121035_2 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001437 262.0
HKD1_k127_1121035_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000002828 177.0
HKD1_k127_1121035_4 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000637 162.0
HKD1_k127_1121035_5 Protein conserved in bacteria K01153 - 3.1.21.3 0.0000000000000000000000005491 108.0
HKD1_k127_1121035_6 regulatory protein, arsR K03892,K21903 - - 0.000000000000000000000007601 104.0
HKD1_k127_11226_0 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 469.0
HKD1_k127_11226_1 N-acetyldiaminopimelate deacetylase activity K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 365.0
HKD1_k127_11226_2 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 359.0
HKD1_k127_11226_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 336.0
HKD1_k127_11226_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 320.0
HKD1_k127_11226_5 PFAM LmbE family protein K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001347 275.0
HKD1_k127_11226_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003102 260.0
HKD1_k127_11226_7 Virulence factor BrkB K07058 - - 0.000000000000000000000000004903 121.0
HKD1_k127_1138561_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 527.0
HKD1_k127_1138561_1 PFAM DNA repair protein RadC K03630 - - 0.000000000000000000000000009228 114.0
HKD1_k127_1138561_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000002129 90.0
HKD1_k127_1138561_3 Protein of unknown function (DUF2958) - - - 0.00000000000003474 73.0
HKD1_k127_1142027_0 Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 323.0
HKD1_k127_1142027_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000026 113.0
HKD1_k127_1147123_0 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000007569 186.0
HKD1_k127_1147123_1 - - - - 0.00000000000000000118 87.0
HKD1_k127_1147123_2 - - - - 0.0000000000001179 71.0
HKD1_k127_1147123_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000004343 73.0
HKD1_k127_1147123_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000003328 58.0
HKD1_k127_1163701_0 Polysaccharide biosynthesis protein K03328 - - 0.000000000000000000000000000000000000000000000000008317 199.0
HKD1_k127_1163701_1 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000055 173.0
HKD1_k127_116467_0 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000002326 244.0
HKD1_k127_116467_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000001224 216.0
HKD1_k127_116467_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000005979 123.0
HKD1_k127_116467_3 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000005727 124.0
HKD1_k127_1171401_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 6.793e-312 970.0
HKD1_k127_1171401_1 ASPIC and UnbV - - - 4.051e-219 696.0
HKD1_k127_1171401_2 ASPIC and UnbV - - - 2.096e-208 666.0
HKD1_k127_1171401_3 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000107 263.0
HKD1_k127_1171401_4 Protein of unknown function (DUF1698) K15257 - - 0.000000000000000000000000000000000000000008569 167.0
HKD1_k127_1171401_5 amino acid - - - 0.000000000000000000000000002547 111.0
HKD1_k127_1174597_0 heat shock protein binding - - - 2.176e-295 939.0
HKD1_k127_1174597_1 heat shock protein binding - - - 8.297e-208 664.0
HKD1_k127_1174597_3 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004658 264.0
HKD1_k127_1174597_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000009375 199.0
HKD1_k127_1174597_5 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000001456 197.0
HKD1_k127_1174597_7 PFAM Tetratricopeptide repeat - - - 0.0000007232 58.0
HKD1_k127_1174597_8 Carboxypeptidase regulatory-like domain - - - 0.0000539 55.0
HKD1_k127_1183204_0 Polysaccharide lyase family 4, domain III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 428.0
HKD1_k127_1183204_1 IclR helix-turn-helix domain K10439 - - 0.0000000000000000000000000000000000000000000001372 179.0
HKD1_k127_1200158_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 1.8e-214 676.0
HKD1_k127_1200158_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000001875 118.0
HKD1_k127_1200158_2 Pfam Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.0000000000000006627 90.0
HKD1_k127_1200158_3 Protein of unknown function (DUF1579) - - - 0.0000000000001823 77.0
HKD1_k127_1200207_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000002766 137.0
HKD1_k127_1200207_1 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000001799 108.0
HKD1_k127_1200207_2 LysR substrate binding domain - - - 0.000000309 55.0
HKD1_k127_1202488_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 597.0
HKD1_k127_1202488_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 346.0
HKD1_k127_1215333_0 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 572.0
HKD1_k127_1215333_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006339 254.0
HKD1_k127_1215333_3 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000008797 212.0
HKD1_k127_1217617_0 Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 472.0
HKD1_k127_1217617_1 TonB-dependent receptor - - - 0.000003815 50.0
HKD1_k127_1219151_0 Belongs to the 'phage' integrase family - - - 0.00000000000000006511 84.0
HKD1_k127_1234512_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 419.0
HKD1_k127_1234512_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001418 277.0
HKD1_k127_1234512_2 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002213 250.0
HKD1_k127_1234512_3 polysaccharide catabolic process K03478 - 3.5.1.105 0.0000000000000000000000000000000004514 140.0
HKD1_k127_1234512_4 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000844 91.0
HKD1_k127_1236171_0 Prokaryotic cytochrome b561 - - - 0.0 1146.0
HKD1_k127_1236171_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 529.0
HKD1_k127_1236171_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 415.0
HKD1_k127_1236171_3 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 377.0
HKD1_k127_1236171_5 IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000003085 194.0
HKD1_k127_1236171_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000006742 115.0
HKD1_k127_1237085_0 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 612.0
HKD1_k127_1237085_1 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 315.0
HKD1_k127_1237085_2 ROK family K00845 - 2.7.1.2 0.000000000000007783 78.0
HKD1_k127_1238375_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1159.0
HKD1_k127_1238375_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.475e-246 769.0
HKD1_k127_1238375_10 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 288.0
HKD1_k127_1238375_11 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009397 244.0
HKD1_k127_1238375_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000008932 175.0
HKD1_k127_1238375_13 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000139 181.0
HKD1_k127_1238375_14 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000006095 176.0
HKD1_k127_1238375_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000003491 135.0
HKD1_k127_1238375_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000002615 135.0
HKD1_k127_1238375_17 Protein of unknown function (DUF3999) - - - 0.0000000000000000000000000000001685 139.0
HKD1_k127_1238375_18 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000002933 93.0
HKD1_k127_1238375_19 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000004466 93.0
HKD1_k127_1238375_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.824e-229 717.0
HKD1_k127_1238375_20 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00002134 52.0
HKD1_k127_1238375_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0001122 49.0
HKD1_k127_1238375_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 500.0
HKD1_k127_1238375_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 416.0
HKD1_k127_1238375_5 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 392.0
HKD1_k127_1238375_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 365.0
HKD1_k127_1238375_7 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 362.0
HKD1_k127_1238375_8 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 353.0
HKD1_k127_1238375_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 292.0
HKD1_k127_123902_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 470.0
HKD1_k127_123902_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 454.0
HKD1_k127_123902_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 367.0
HKD1_k127_123902_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000001453 106.0
HKD1_k127_125297_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 8.427e-199 631.0
HKD1_k127_125297_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 538.0
HKD1_k127_125297_2 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000005387 84.0
HKD1_k127_125297_3 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000007709 72.0
HKD1_k127_1254705_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.888e-320 1000.0
HKD1_k127_1254705_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 9.483e-265 839.0
HKD1_k127_1254705_10 Histidine kinase - - - 0.0000000000000000000000000001361 123.0
HKD1_k127_1254705_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000004209 100.0
HKD1_k127_1254705_12 R3H domain K06346 - - 0.00000000000000000009354 94.0
HKD1_k127_1254705_13 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000001007 97.0
HKD1_k127_1254705_14 - - - - 0.000000000000000001631 87.0
HKD1_k127_1254705_15 multi-organism process - - - 0.0000000000000001182 89.0
HKD1_k127_1254705_16 - - - - 0.0000000000000002295 87.0
HKD1_k127_1254705_17 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000003714 80.0
HKD1_k127_1254705_18 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000008711 66.0
HKD1_k127_1254705_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.269e-242 763.0
HKD1_k127_1254705_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 468.0
HKD1_k127_1254705_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 429.0
HKD1_k127_1254705_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 380.0
HKD1_k127_1254705_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 347.0
HKD1_k127_1254705_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 329.0
HKD1_k127_1254705_8 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002173 247.0
HKD1_k127_1254705_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000002595 231.0
HKD1_k127_1270648_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 453.0
HKD1_k127_1270648_1 Belongs to the RuBisCO large chain family K08965 - 5.3.2.5 0.0000000000000000000000000000000000004604 149.0
HKD1_k127_1270648_2 rpiR family - - - 0.000000000000000000000000000000000008086 147.0
HKD1_k127_127844_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2206.0
HKD1_k127_127844_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1708.0
HKD1_k127_127844_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 338.0
HKD1_k127_127844_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003373 250.0
HKD1_k127_127844_4 Ribosomal protein L11/L12 K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000001699 231.0
HKD1_k127_127844_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000007161 171.0
HKD1_k127_127844_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000004276 160.0
HKD1_k127_127844_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000004385 98.0
HKD1_k127_127844_8 Ribosomal protein L33 K02913 - - 0.0000000000000000006671 86.0
HKD1_k127_127844_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000127 63.0
HKD1_k127_1286306_0 Major facilitator Superfamily K02511,K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 420.0
HKD1_k127_1286306_1 PRC-barrel domain - - - 0.0000000000000000000007469 106.0
HKD1_k127_1286306_2 Belongs to the pirin family K06911 - - 0.0000000107 56.0
HKD1_k127_1286884_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 523.0
HKD1_k127_1286884_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 497.0
HKD1_k127_1286884_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 450.0
HKD1_k127_1286884_3 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 297.0
HKD1_k127_1286884_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000001234 256.0
HKD1_k127_1286884_5 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000001641 150.0
HKD1_k127_1286884_6 Methyltransferase type 11 K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000001157 139.0
HKD1_k127_1299415_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 496.0
HKD1_k127_1299415_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 296.0
HKD1_k127_1299415_2 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000471 130.0
HKD1_k127_1299415_3 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.0000002853 55.0
HKD1_k127_1299415_4 Protein involved in meta-pathway of phenol degradation - - - 0.0001187 48.0
HKD1_k127_1302072_0 Transcriptional regulator - - - 0.00000000000002145 76.0
HKD1_k127_1302072_1 response regulator - - - 0.000000000008917 74.0
HKD1_k127_1302072_2 Phospholipid methyltransferase - - - 0.00000000008864 68.0
HKD1_k127_1310968_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003858 273.0
HKD1_k127_1310968_1 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000001578 207.0
HKD1_k127_1311202_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1123.0
HKD1_k127_1311202_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.864e-254 791.0
HKD1_k127_1311202_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.77e-233 725.0
HKD1_k127_1311202_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 539.0
HKD1_k127_1311202_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 316.0
HKD1_k127_1311202_5 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006039 284.0
HKD1_k127_1311202_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004139 277.0
HKD1_k127_1311202_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000004772 198.0
HKD1_k127_1311202_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000001331 184.0
HKD1_k127_1311202_9 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000001746 94.0
HKD1_k127_1326756_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1418.0
HKD1_k127_1326756_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1072.0
HKD1_k127_1326756_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 545.0
HKD1_k127_1326756_3 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 492.0
HKD1_k127_1326756_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 435.0
HKD1_k127_1326756_5 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002023 286.0
HKD1_k127_1326756_6 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000003095 141.0
HKD1_k127_1326756_7 Regulatory protein RecX K03565 - - 0.000000000004853 74.0
HKD1_k127_1326756_8 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000008926 70.0
HKD1_k127_1326996_0 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1206.0
HKD1_k127_1326996_1 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 452.0
HKD1_k127_1346889_0 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 404.0
HKD1_k127_1346889_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002342 250.0
HKD1_k127_1350863_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1012.0
HKD1_k127_1350863_1 amidohydrolase - - - 0.0000000000000000000000000000000000000003004 156.0
HKD1_k127_1354601_0 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 476.0
HKD1_k127_1354601_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 435.0
HKD1_k127_1354601_10 CYTH K05873 - 4.6.1.1 0.000000000000000000004781 98.0
HKD1_k127_1354601_11 - - - - 0.00000293 53.0
HKD1_k127_1354601_2 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 327.0
HKD1_k127_1354601_3 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 313.0
HKD1_k127_1354601_4 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 297.0
HKD1_k127_1354601_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004294 283.0
HKD1_k127_1354601_6 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005455 259.0
HKD1_k127_1354601_7 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000007966 142.0
HKD1_k127_1354601_8 Cold shock K03704 - - 0.00000000000000000000004894 103.0
HKD1_k127_1354601_9 Belongs to the ompA family - - - 0.00000000000000000000005139 108.0
HKD1_k127_1361048_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001266 300.0
HKD1_k127_1361048_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000002614 163.0
HKD1_k127_1372198_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 539.0
HKD1_k127_1372198_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000001365 169.0
HKD1_k127_1372198_2 DinB superfamily - - - 0.00000000000000000000000001214 114.0
HKD1_k127_1372198_3 - - - - 0.000000000000000000002683 102.0
HKD1_k127_1389989_0 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005366 269.0
HKD1_k127_1389989_1 protein secretion K09800 - - 0.000000000000000000000000000000001612 136.0
HKD1_k127_139054_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.717e-206 653.0
HKD1_k127_139054_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.215e-197 628.0
HKD1_k127_139054_10 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000003366 250.0
HKD1_k127_139054_11 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000003547 156.0
HKD1_k127_139054_12 PFAM penicillin-binding protein transpeptidase, Penicillin-binding protein dimerization domain-containing protein, PASTA domain containing protein K08384 - - 0.0000000000001845 74.0
HKD1_k127_139054_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000000000001588 73.0
HKD1_k127_139054_14 Tetratricopeptide repeat - - - 0.00000001353 67.0
HKD1_k127_139054_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 491.0
HKD1_k127_139054_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 438.0
HKD1_k127_139054_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 437.0
HKD1_k127_139054_5 LOR SDH bifunctional enzyme conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 388.0
HKD1_k127_139054_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 361.0
HKD1_k127_139054_7 Bacterial regulatory protein, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 307.0
HKD1_k127_139054_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 299.0
HKD1_k127_139054_9 ZIP Zinc transporter K07238,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005171 269.0
HKD1_k127_1404533_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 570.0
HKD1_k127_1404533_1 Universal stress protein - - - 0.0000000000000000000008137 101.0
HKD1_k127_1412331_0 PFAM type III restriction protein res subunit - - - 7.17e-313 978.0
HKD1_k127_1412331_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 409.0
HKD1_k127_1412331_2 Transcriptional regulator, AbiEi antitoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002432 276.0
HKD1_k127_1412331_3 Endonuclease containing a URI domain - - - 0.0000000000000000000001271 99.0
HKD1_k127_1412331_4 Replication-relaxation - - - 0.0005965 51.0
HKD1_k127_1423623_0 Aminotransferase class-V K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000002315 247.0
HKD1_k127_1423623_1 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000004525 192.0
HKD1_k127_1423623_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000009457 127.0
HKD1_k127_1423623_3 von Willebrand factor, type A - - - 0.000000000000000000003499 105.0
HKD1_k127_1423623_4 - - - - 0.0000000001949 73.0
HKD1_k127_1425722_0 Sulfate permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 600.0
HKD1_k127_1425722_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 474.0
HKD1_k127_1425722_2 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 293.0
HKD1_k127_1425722_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000002505 130.0
HKD1_k127_1425722_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000007783 109.0
HKD1_k127_1425722_5 PFAM amino acid-binding ACT domain protein - - - 0.0001157 50.0
HKD1_k127_1443566_0 Asparagine synthase K01953 - 6.3.5.4 1.674e-212 678.0
HKD1_k127_1443566_1 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000007033 109.0
HKD1_k127_1443566_2 HPr kinase - - - 0.000000000000000000000001553 115.0
HKD1_k127_1443566_3 Transglutaminase-like superfamily - - - 0.000000000000000001587 90.0
HKD1_k127_1470455_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 569.0
HKD1_k127_1470455_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 473.0
HKD1_k127_1470455_2 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 354.0
HKD1_k127_1470455_3 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 300.0
HKD1_k127_1470455_4 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.000000000000000000000000004491 111.0
HKD1_k127_1471868_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 557.0
HKD1_k127_1471868_1 transferase activity, transferring glycosyl groups K18785 - 2.4.1.319,2.4.1.320 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 462.0
HKD1_k127_1471868_2 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.00000000000000000000000000000000008583 135.0
HKD1_k127_1477544_0 C-terminal region of aryl-sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 548.0
HKD1_k127_1477544_1 acetylesterase activity - - - 0.00000000000000000000000000000000008258 139.0
HKD1_k127_1492651_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000006065 222.0
HKD1_k127_1492651_1 DinB superfamily - - - 0.000000000000000000000000000000000000000000000003189 178.0
HKD1_k127_1492651_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000006598 168.0
HKD1_k127_1501978_0 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 522.0
HKD1_k127_1501978_1 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 306.0
HKD1_k127_1501978_2 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000006597 210.0
HKD1_k127_1501978_3 oxidoreductase activity - - - 0.0000000000000000000001065 106.0
HKD1_k127_1501978_4 cell redox homeostasis - - - 0.0000000000000000000004814 108.0
HKD1_k127_1515385_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008081 265.0
HKD1_k127_1515385_1 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000001104 109.0
HKD1_k127_1515385_2 Protein of unknown function (DUF2911) - - - 0.00000000000000009356 86.0
HKD1_k127_1519954_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000000000000001006 194.0
HKD1_k127_1519954_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000006904 162.0
HKD1_k127_1519954_2 membrane-associated protein - - - 0.00000002959 63.0
HKD1_k127_1521183_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 341.0
HKD1_k127_1521183_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000143 89.0
HKD1_k127_1526271_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006251 271.0
HKD1_k127_1526271_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000002093 226.0
HKD1_k127_1526271_2 Transcriptional regulator K13641 - - 0.0000000000000000000000000000000000000000000001241 179.0
HKD1_k127_1526271_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000111 175.0
HKD1_k127_1526271_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000006757 168.0
HKD1_k127_1529226_0 Putative oxidoreductase C terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 478.0
HKD1_k127_1529226_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 335.0
HKD1_k127_1529226_2 Oxidoreductase family, NAD-binding Rossmann fold K18106 - - 0.00000000000000000000000000000000000000000000000000000000002069 222.0
HKD1_k127_1529226_3 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000007382 213.0
HKD1_k127_1529226_4 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000000000007247 133.0
HKD1_k127_1529226_5 PFAM Cys Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.000002774 52.0
HKD1_k127_152949_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 595.0
HKD1_k127_152949_1 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000148 126.0
HKD1_k127_1529630_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 393.0
HKD1_k127_1529630_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000006127 206.0
HKD1_k127_1533115_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 320.0
HKD1_k127_1533115_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000000000000000000000000000001217 214.0
HKD1_k127_1533115_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000008406 108.0
HKD1_k127_1535160_0 radical SAM domain protein - - - 5.923e-226 710.0
HKD1_k127_1535160_1 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 9.223e-196 616.0
HKD1_k127_1535160_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
HKD1_k127_1535160_11 BON domain - - - 0.000000000000000000000000000000000000000000000000000000002857 205.0
HKD1_k127_1535160_12 Histidine kinase K02478 - 2.7.13.3 0.00000000000001871 77.0
HKD1_k127_1535160_14 - - - - 0.0000872 50.0
HKD1_k127_1535160_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 632.0
HKD1_k127_1535160_3 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 523.0
HKD1_k127_1535160_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 369.0
HKD1_k127_1535160_5 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 344.0
HKD1_k127_1535160_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001543 267.0
HKD1_k127_1535160_7 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004108 258.0
HKD1_k127_1535160_8 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002913 256.0
HKD1_k127_1535160_9 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 256.0
HKD1_k127_1543481_0 AcrB/AcrD/AcrF family K03296 - - 2.747e-321 1007.0
HKD1_k127_1543481_1 Domain of unknown function (DUF1998) K06877 - - 1.51e-318 993.0
HKD1_k127_1543481_11 Cupin domain - - - 0.00000000000000000000000000000000000000000000000004791 181.0
HKD1_k127_1543481_12 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000000000000000009126 161.0
HKD1_k127_1543481_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000396 157.0
HKD1_k127_1543481_2 Prolyl oligopeptidase family - - - 1.875e-226 720.0
HKD1_k127_1543481_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 617.0
HKD1_k127_1543481_4 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 580.0
HKD1_k127_1543481_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 501.0
HKD1_k127_1543481_6 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 466.0
HKD1_k127_1543481_7 Glycosyl hydrolases family 28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007653 259.0
HKD1_k127_1543481_8 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000001386 229.0
HKD1_k127_1543481_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000002303 218.0
HKD1_k127_1554858_0 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HKD1_k127_1554858_1 Methane oxygenase PmoA - - - 0.000000000000000000000000000000000000000000000000000000000000000000005442 248.0
HKD1_k127_1554858_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000003274 176.0
HKD1_k127_1554858_3 HupE / UreJ protein - - - 0.000000001253 65.0
HKD1_k127_1554858_4 Formate dehydrogenase subunit alpha - - - 0.0002758 45.0
HKD1_k127_1558176_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 619.0
HKD1_k127_1558176_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 633.0
HKD1_k127_1558176_2 - K19693 - - 0.000000009192 57.0
HKD1_k127_1563482_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 445.0
HKD1_k127_1563482_1 saccharopine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 299.0
HKD1_k127_1563482_2 haloacid dehalogenase-like hydrolase K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000012 228.0
HKD1_k127_1565577_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 329.0
HKD1_k127_1565577_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 307.0
HKD1_k127_1565577_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006097 295.0
HKD1_k127_1565577_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001136 277.0
HKD1_k127_1565577_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000001758 174.0
HKD1_k127_1565577_5 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000009236 149.0
HKD1_k127_1565577_6 Putative zinc-finger - GO:0005575,GO:0016020 - 0.0002943 51.0
HKD1_k127_1567388_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 295.0
HKD1_k127_1567388_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000008205 166.0
HKD1_k127_1567388_2 polysaccharide deacetylase - - - 0.00000000000003457 78.0
HKD1_k127_15722_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 395.0
HKD1_k127_15722_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 385.0
HKD1_k127_15722_2 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000000000000000000004208 231.0
HKD1_k127_15722_3 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000263 112.0
HKD1_k127_15722_4 serine threonine protein kinase K12132 - 2.7.11.1 0.00000006817 65.0
HKD1_k127_1578296_0 L-lysine catabolic process to acetate K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000005741 240.0
HKD1_k127_1578296_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000001145 172.0
HKD1_k127_1578296_2 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.00000000000000000000000000000000000002561 154.0
HKD1_k127_1593430_0 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 357.0
HKD1_k127_1593430_1 PFAM ABC transporter related K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 312.0
HKD1_k127_1593430_2 rRNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000003737 194.0
HKD1_k127_1607372_0 DinB family - - - 0.000000000000000000000000000000000000005197 154.0
HKD1_k127_1607372_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000917 144.0
HKD1_k127_1607372_2 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000003671 113.0
HKD1_k127_1607372_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0001548 46.0
HKD1_k127_1618933_0 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000009216 207.0
HKD1_k127_1618933_1 - - - - 0.00000000000000000000000000000000000000000000000000000008148 200.0
HKD1_k127_1618933_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000001032 91.0
HKD1_k127_1618933_3 Acetyltransferase (GNAT) family - - - 0.00000000002526 64.0
HKD1_k127_1618933_4 Enoyl-(Acyl carrier protein) reductase K00059,K17739 - 1.1.1.100,1.1.1.252 0.0000000001673 63.0
HKD1_k127_1618933_5 - - - - 0.00000003136 61.0
HKD1_k127_1646284_0 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 488.0
HKD1_k127_1646284_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008846 274.0
HKD1_k127_1648403_0 Sodium/calcium exchanger protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 577.0
HKD1_k127_1648403_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 541.0
HKD1_k127_1648403_2 PFAM TonB-dependent Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 443.0
HKD1_k127_1648403_3 - - - - 0.000000000000000000000000000000001374 135.0
HKD1_k127_1648403_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000008661 71.0
HKD1_k127_1648403_5 - - - - 0.000000000001732 76.0
HKD1_k127_1649801_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002812 267.0
HKD1_k127_1649801_1 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000001108 186.0
HKD1_k127_1649801_2 Domain of unknown function (DUF4203) - - - 0.000000000000000000000001781 109.0
HKD1_k127_1649801_3 Universal stress protein family - - - 0.0000000000000000000003591 102.0
HKD1_k127_1649801_4 - - - - 0.0000000000000000000008614 99.0
HKD1_k127_1649801_5 - - - - 0.0000000002142 63.0
HKD1_k127_1654469_0 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000001042 258.0
HKD1_k127_1654469_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000005606 233.0
HKD1_k127_1654469_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000009231 222.0
HKD1_k127_1654469_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000007536 191.0
HKD1_k127_167438_0 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 541.0
HKD1_k127_167438_1 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 444.0
HKD1_k127_167438_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000001321 184.0
HKD1_k127_167438_3 Haloacid dehalogenase-like hydrolase - GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0010941,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019899,GO:0042578,GO:0042981,GO:0043067,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007,GO:2000269 - 0.0000000000004551 72.0
HKD1_k127_167438_4 - - - - 0.0001013 51.0
HKD1_k127_1689904_0 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 335.0
HKD1_k127_1689904_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007732 254.0
HKD1_k127_1689904_2 TraB family K09973 - - 0.0000000000000000000000000000000000000000001884 166.0
HKD1_k127_1693378_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.038e-214 680.0
HKD1_k127_1693378_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 392.0
HKD1_k127_1693378_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 363.0
HKD1_k127_1693378_3 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 316.0
HKD1_k127_1693378_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 297.0
HKD1_k127_1693378_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 266.0
HKD1_k127_1693378_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000008773 199.0
HKD1_k127_1693378_7 photosynthesis - - - 0.000000000000000000000000000000000000002137 152.0
HKD1_k127_1693378_8 e3 binding domain - - - 0.0000000000000000000000001088 108.0
HKD1_k127_1693378_9 aminopeptidase activity K01301 - 3.4.17.21 0.0000000000000000006816 87.0
HKD1_k127_1717436_0 Uncharacterized protein family (UPF0051) K09014 - - 9.063e-283 872.0
HKD1_k127_1717436_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 8.7e-249 776.0
HKD1_k127_1717436_10 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000002878 157.0
HKD1_k127_1717436_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000000000347 149.0
HKD1_k127_1717436_12 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000000000000000000000000000005403 136.0
HKD1_k127_1717436_13 Transcriptional regulator - - - 0.00000000000000000000000000002186 123.0
HKD1_k127_1717436_14 Fibronectin type 3 domain - - - 0.00000000000000000000000002395 117.0
HKD1_k127_1717436_15 Biotin-requiring enzyme - - - 0.00000000000000000000000004968 114.0
HKD1_k127_1717436_16 - - - - 0.00000000009781 71.0
HKD1_k127_1717436_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 589.0
HKD1_k127_1717436_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 588.0
HKD1_k127_1717436_4 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 560.0
HKD1_k127_1717436_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 520.0
HKD1_k127_1717436_6 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 429.0
HKD1_k127_1717436_7 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 381.0
HKD1_k127_1717436_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 327.0
HKD1_k127_1717436_9 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000000000000000974 207.0
HKD1_k127_1735280_0 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 293.0
HKD1_k127_1735280_1 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000001474 177.0
HKD1_k127_1735280_2 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000009754 74.0
HKD1_k127_1740681_0 Pfam:N_methyl_2 K02459 - - 0.000000004224 66.0
HKD1_k127_1740681_1 Prokaryotic N-terminal methylation motif - - - 0.00001035 55.0
HKD1_k127_1740681_2 Prokaryotic N-terminal methylation motif K02458 - - 0.0005593 49.0
HKD1_k127_17425_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 548.0
HKD1_k127_17425_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 526.0
HKD1_k127_17425_10 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000003212 141.0
HKD1_k127_17425_11 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000001285 138.0
HKD1_k127_17425_12 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000224 134.0
HKD1_k127_17425_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000009574 124.0
HKD1_k127_17425_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000002355 117.0
HKD1_k127_17425_15 Peptidoglycan binding domain - - - 0.000003624 59.0
HKD1_k127_17425_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 436.0
HKD1_k127_17425_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 351.0
HKD1_k127_17425_4 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 305.0
HKD1_k127_17425_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006865 271.0
HKD1_k127_17425_6 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000003635 216.0
HKD1_k127_17425_7 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000002405 179.0
HKD1_k127_17425_8 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.0000000000000000000000000000000000000000000002338 185.0
HKD1_k127_17425_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000004111 163.0
HKD1_k127_1744350_0 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000005311 229.0
HKD1_k127_1744350_1 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000001556 229.0
HKD1_k127_1744350_2 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000001697 183.0
HKD1_k127_1744350_3 Pfam Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000003982 179.0
HKD1_k127_1744350_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000005717 157.0
HKD1_k127_1744350_5 SPTR D1C1B9 DinB family protein - - - 0.00000005311 56.0
HKD1_k127_1754684_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000008675 237.0
HKD1_k127_1754684_1 Putative RNA methylase family UPF0020 - - - 0.0000000000000000000000000000000000000000000000000005592 204.0
HKD1_k127_1754684_2 CopG antitoxin of type II toxin-antitoxin system - - - 0.0005948 42.0
HKD1_k127_1762008_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.674e-200 631.0
HKD1_k127_1762008_1 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 527.0
HKD1_k127_1762008_2 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 377.0
HKD1_k127_1763532_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 474.0
HKD1_k127_1763532_1 - - - - 0.0000000000000000009225 92.0
HKD1_k127_1763532_2 - - - - 0.00000000000000001413 91.0
HKD1_k127_1763532_3 glycogen debranching enzyme GlgX K01214 - 3.2.1.68 0.00000001252 59.0
HKD1_k127_1778883_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 569.0
HKD1_k127_1778883_1 ABC-type nitrate sulfonate bicarbonate transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 311.0
HKD1_k127_1778883_2 PA domain K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000805 100.0
HKD1_k127_1783738_0 Beta-eliminating lyase K01668 - 4.1.99.2 1.766e-233 731.0
HKD1_k127_1783738_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.231e-208 661.0
HKD1_k127_1783738_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 586.0
HKD1_k127_1783738_3 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005123 287.0
HKD1_k127_1783738_4 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000002383 213.0
HKD1_k127_1783738_6 hyperosmotic response - - - 0.000000000000000000000002876 111.0
HKD1_k127_1783738_7 O-Glycosyl hydrolase family 30 - - - 0.0000000000000000000007352 110.0
HKD1_k127_1783738_8 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000006024 89.0
HKD1_k127_1786409_0 Domain of unknown function (DUF1846) - - - 5.127e-250 780.0
HKD1_k127_1786409_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
HKD1_k127_1786409_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000003545 131.0
HKD1_k127_1786409_3 Protein of unknown function (DUF1059) - - - 0.00001088 51.0
HKD1_k127_1800888_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 505.0
HKD1_k127_1800888_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 373.0
HKD1_k127_1800888_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 318.0
HKD1_k127_1800888_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002066 277.0
HKD1_k127_1800888_4 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 272.0
HKD1_k127_1800888_5 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000005852 253.0
HKD1_k127_1800888_6 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
HKD1_k127_1800888_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000001535 215.0
HKD1_k127_1800888_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000001433 102.0
HKD1_k127_1807345_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1311.0
HKD1_k127_1807345_1 beta-galactosidase activity K05989 - 3.2.1.40 1.093e-264 852.0
HKD1_k127_1807345_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 551.0
HKD1_k127_1807345_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000001011 228.0
HKD1_k127_1807345_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000002293 208.0
HKD1_k127_1807345_5 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000008323 145.0
HKD1_k127_1807345_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K18009 - 1.1.1.304,1.1.1.76 0.00000109 51.0
HKD1_k127_1807345_7 von Willebrand factor (vWF) type A domain - - - 0.0008285 47.0
HKD1_k127_1822878_0 Sulfate permease family K03321 - - 9.908e-238 748.0
HKD1_k127_1822878_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 345.0
HKD1_k127_1822878_2 PFAM Mannosyl oligosaccharide glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 296.0
HKD1_k127_1822878_3 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000004104 216.0
HKD1_k127_1822878_4 YHS domain - - - 0.000000000000000000000000000000000000000000001699 170.0
HKD1_k127_1822878_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000004438 169.0
HKD1_k127_1822878_6 DoxX-like family - - - 0.00000000000000000000000000000000005429 139.0
HKD1_k127_1828879_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000003588 194.0
HKD1_k127_1828879_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000001622 190.0
HKD1_k127_1828879_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000003443 149.0
HKD1_k127_1828879_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000002156 132.0
HKD1_k127_1828879_4 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00001723 55.0
HKD1_k127_1831791_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000003237 179.0
HKD1_k127_1831791_1 polygalacturonase activity - - - 0.00000000006757 65.0
HKD1_k127_1831791_2 Aminoglycoside phosphotransferase - - - 0.00000000009959 71.0
HKD1_k127_1831791_3 Phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.00000009516 54.0
HKD1_k127_1835066_0 Carboxypeptidase regulatory-like domain - - - 3.869e-249 790.0
HKD1_k127_1835066_1 PFAM ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 444.0
HKD1_k127_1835066_2 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 335.0
HKD1_k127_1835066_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003194 263.0
HKD1_k127_1835066_4 Hypothetical glycosyl hydrolase 6 K01190,K12308 - 3.2.1.23 0.000000000000000000000000000000000000004434 168.0
HKD1_k127_1836917_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 606.0
HKD1_k127_1836917_1 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000003186 176.0
HKD1_k127_1836917_2 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000001886 129.0
HKD1_k127_1853112_0 Tricorn protease C1 domain K08676 - - 3.562e-203 641.0
HKD1_k127_1853112_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 579.0
HKD1_k127_1853112_2 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 384.0
HKD1_k127_1853112_3 Conserved carboxylase domain K01958 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 298.0
HKD1_k127_1867468_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000593 259.0
HKD1_k127_1867468_1 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000001567 165.0
HKD1_k127_1867468_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000004192 102.0
HKD1_k127_1867468_3 PFAM HypF finger K04656 - - 0.00000000000000002345 85.0
HKD1_k127_1867468_4 PFAM 3D domain - - - 0.00000000000005938 78.0
HKD1_k127_1867468_5 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.0000000000004801 72.0
HKD1_k127_1869225_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 418.0
HKD1_k127_1869225_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000001186 178.0
HKD1_k127_1869225_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000001733 169.0
HKD1_k127_1869225_3 Protein of unknown function (DUF2905) - - - 0.000000000000002081 78.0
HKD1_k127_1901138_0 Protein of unknown function (DUF1565) - - - 9.803e-248 779.0
HKD1_k127_1901138_1 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 362.0
HKD1_k127_1901138_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000003733 231.0
HKD1_k127_1901138_3 - - - - 0.0000000000000000000000000000001368 131.0
HKD1_k127_1901138_4 DinB superfamily - - - 0.000000000000003979 75.0
HKD1_k127_1904031_0 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 438.0
HKD1_k127_1904031_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000002077 227.0
HKD1_k127_1904031_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000002399 217.0
HKD1_k127_1904031_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000004925 163.0
HKD1_k127_1904031_4 Peptidase family M50 - - - 0.00000000000001382 75.0
HKD1_k127_190536_0 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000002755 216.0
HKD1_k127_190536_1 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000003108 190.0
HKD1_k127_190536_2 NUDIX domain K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000001266 170.0
HKD1_k127_190536_3 Tetratricopeptide repeat - - - 0.00000000000000000000001331 103.0
HKD1_k127_1913823_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1458.0
HKD1_k127_1913823_1 Peptidase family M3 K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 572.0
HKD1_k127_1913823_10 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000001076 84.0
HKD1_k127_1913823_11 Putative adhesin - - - 0.0000002631 55.0
HKD1_k127_1913823_12 Sugar ABC transporter permease K15771 - - 0.0001799 49.0
HKD1_k127_1913823_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 527.0
HKD1_k127_1913823_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 443.0
HKD1_k127_1913823_4 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 374.0
HKD1_k127_1913823_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 372.0
HKD1_k127_1913823_6 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 314.0
HKD1_k127_1913823_7 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HKD1_k127_1913823_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000001361 201.0
HKD1_k127_1913823_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000001116 152.0
HKD1_k127_1923028_0 PFAM Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 354.0
HKD1_k127_1923028_1 - - - - 0.000000000000000000000006197 108.0
HKD1_k127_1929989_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 582.0
HKD1_k127_1929989_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 403.0
HKD1_k127_1929989_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 340.0
HKD1_k127_1929989_3 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000005264 220.0
HKD1_k127_1929989_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000006251 130.0
HKD1_k127_1936233_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 314.0
HKD1_k127_1936233_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000001806 122.0
HKD1_k127_1936233_2 Regulates arginine biosynthesis genes K03402 - - 0.00000005622 55.0
HKD1_k127_1940981_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 489.0
HKD1_k127_1940981_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000002461 130.0
HKD1_k127_19456_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000009699 190.0
HKD1_k127_196075_0 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 580.0
HKD1_k127_196075_1 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 462.0
HKD1_k127_196075_2 TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 444.0
HKD1_k127_196075_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000003402 216.0
HKD1_k127_196075_4 - - - - 0.0000000000000000000000000000000000000000000000483 184.0
HKD1_k127_196075_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000007104 169.0
HKD1_k127_196075_7 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000005112 106.0
HKD1_k127_196075_8 peptidyl-tyrosine sulfation - - - 0.00000000000001 89.0
HKD1_k127_196075_9 Penicillin-binding protein, transpeptidase domain protein K05515 - 3.4.16.4 0.000000000008581 76.0
HKD1_k127_1960932_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 503.0
HKD1_k127_1960932_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 298.0
HKD1_k127_1960932_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000001252 211.0
HKD1_k127_1960932_3 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000005877 202.0
HKD1_k127_1972028_0 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 456.0
HKD1_k127_1972028_1 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 417.0
HKD1_k127_1972028_2 PFAM Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005788 244.0
HKD1_k127_1975653_0 HAD-superfamily subfamily IIA hydrolase - - - 0.00000000000000000000000000000000000000000000000000000009328 201.0
HKD1_k127_1975653_1 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000000000000000000001085 212.0
HKD1_k127_1977294_0 Melibiase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 362.0
HKD1_k127_1977294_1 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000006512 163.0
HKD1_k127_1977294_2 PFAM Flp Fap pilin component K02651 - - 0.00001126 49.0
HKD1_k127_1985718_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 1.789e-292 918.0
HKD1_k127_1985718_1 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 326.0
HKD1_k127_1985718_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000006616 135.0
HKD1_k127_1985718_3 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.0000000000000003616 90.0
HKD1_k127_1999866_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1042.0
HKD1_k127_1999866_1 AMP-binding enzyme C-terminal domain K00666 - - 5.054e-229 721.0
HKD1_k127_1999866_10 - - - - 0.0000000000000009615 83.0
HKD1_k127_1999866_11 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000001892 86.0
HKD1_k127_1999866_12 glycosyl transferase family 2 - - - 0.0000001026 58.0
HKD1_k127_1999866_2 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 612.0
HKD1_k127_1999866_3 Melibiase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 445.0
HKD1_k127_1999866_4 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 400.0
HKD1_k127_1999866_5 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 321.0
HKD1_k127_1999866_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000003223 211.0
HKD1_k127_1999866_7 BMC - - - 0.000000000000000000000000000000000000000000000001193 180.0
HKD1_k127_1999866_8 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.000000000000000000000002778 106.0
HKD1_k127_1999866_9 PFAM CHAD domain containing protein - - - 0.0000000000000000005193 98.0
HKD1_k127_2008252_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000001152 228.0
HKD1_k127_2008252_1 transferase activity, transferring glycosyl groups - - - 0.000007889 54.0
HKD1_k127_2016899_0 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 495.0
HKD1_k127_2016899_1 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 458.0
HKD1_k127_2016899_10 - - - - 0.00000000000003316 75.0
HKD1_k127_2016899_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000001023 78.0
HKD1_k127_2016899_2 aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
HKD1_k127_2016899_3 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 343.0
HKD1_k127_2016899_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 354.0
HKD1_k127_2016899_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000004331 216.0
HKD1_k127_2016899_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000004746 190.0
HKD1_k127_2016899_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000002442 160.0
HKD1_k127_2016899_8 Reverse transcriptase-like - - - 0.000000000000000000000000000000001311 139.0
HKD1_k127_2016899_9 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000001118 136.0
HKD1_k127_2029071_0 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 428.0
HKD1_k127_2029071_1 Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000001341 174.0
HKD1_k127_2029071_2 bacterial-type flagellum-dependent cell motility - - - 0.0000006792 63.0
HKD1_k127_2029071_3 chitinase K01183 - 3.2.1.14 0.00001405 59.0
HKD1_k127_2034589_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000001565 194.0
HKD1_k127_2034589_1 viral genome integration into host DNA K04763 - - 0.0000000000000000000000000000000000000000000000001466 179.0
HKD1_k127_2034589_2 - - - - 0.000000000000000000000189 109.0
HKD1_k127_2034589_3 viral genome integration into host DNA K04763 - - 0.000000000000676 72.0
HKD1_k127_2034589_4 viral genome integration into host DNA K04763 - - 0.00000525 50.0
HKD1_k127_2034589_5 - - - - 0.00003361 54.0
HKD1_k127_2037459_0 Polysulphide reductase, NrfD K00185 - - 1.045e-219 689.0
HKD1_k127_2037459_1 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002569 248.0
HKD1_k127_2037459_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000001001 247.0
HKD1_k127_2040620_0 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000351 84.0
HKD1_k127_2040620_1 TadE-like protein - - - 0.00000000008842 69.0
HKD1_k127_2040620_2 PFAM TadE family protein - - - 0.000000005184 63.0
HKD1_k127_2055795_0 peroxidase activity K00435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 294.0
HKD1_k127_2055795_1 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000001576 228.0
HKD1_k127_2055795_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000000000000000000000000000000000000000000000005171 217.0
HKD1_k127_2055795_3 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000001121 212.0
HKD1_k127_2055795_4 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000007934 205.0
HKD1_k127_2055795_5 ABC-type transport system involved in cytochrome c biogenesis, permease component K02194 - - 0.0000000000000000000000000000000000000000000000000006972 192.0
HKD1_k127_2055795_6 - - - - 0.00000000000000000000000000000000000002114 156.0
HKD1_k127_2055795_7 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000004534 157.0
HKD1_k127_2055795_8 chaperone-mediated protein folding - - - 0.00000000000000000000381 106.0
HKD1_k127_2055795_9 - - - - 0.0000000000000000002637 100.0
HKD1_k127_2057172_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 329.0
HKD1_k127_2057172_1 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000000000000000000000000000000000456 180.0
HKD1_k127_2057172_2 Tetratricopeptide repeat - - - 0.00005899 51.0
HKD1_k127_2059136_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.779e-312 996.0
HKD1_k127_2059136_1 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000007887 267.0
HKD1_k127_2059136_10 Serine aminopeptidase, S33 - - - 0.0000000001095 74.0
HKD1_k127_2059136_2 MOSC domain containing protein K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009488 263.0
HKD1_k127_2059136_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001921 265.0
HKD1_k127_2059136_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000002889 215.0
HKD1_k127_2059136_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000004594 210.0
HKD1_k127_2059136_6 PFAM DinB family - - - 0.00000000000000000000000000000000000000000000000000000239 196.0
HKD1_k127_2059136_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000129 187.0
HKD1_k127_2059136_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000004062 190.0
HKD1_k127_2059136_9 PFAM RNA-binding S4 - - - 0.0000000000004942 73.0
HKD1_k127_2070420_0 Fatty acid desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 439.0
HKD1_k127_2090452_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 382.0
HKD1_k127_2090452_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 329.0
HKD1_k127_2090452_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000005517 201.0
HKD1_k127_2090452_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000009401 121.0
HKD1_k127_2096399_0 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000002407 180.0
HKD1_k127_2101373_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 326.0
HKD1_k127_2101373_1 Peptidase M56, BlaR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
HKD1_k127_2101373_2 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003595 278.0
HKD1_k127_2101373_3 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000002101 240.0
HKD1_k127_2101373_4 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.00000000000000000000000000000000000000000000000000000000000002215 228.0
HKD1_k127_2101373_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000003591 209.0
HKD1_k127_2101373_6 PFAM Penicillinase repressor - - - 0.000000000000000000000000000000000000000000000001281 178.0
HKD1_k127_2101373_7 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000004424 166.0
HKD1_k127_2101373_8 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000001222 139.0
HKD1_k127_2111149_0 Zinc-binding dehydrogenase K17818 - 1.1.1.287 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 317.0
HKD1_k127_2111149_1 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 310.0
HKD1_k127_2111149_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000007195 183.0
HKD1_k127_2122820_0 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 445.0
HKD1_k127_2122820_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
HKD1_k127_2122820_2 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
HKD1_k127_2122820_3 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000003757 130.0
HKD1_k127_2122820_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000001498 128.0
HKD1_k127_2122820_5 PFAM glutaredoxin K18917 - 1.20.4.3 0.00000000002218 69.0
HKD1_k127_2130209_0 SMART Elongator protein 3 MiaB NifB - - - 7.579e-224 701.0
HKD1_k127_2130209_1 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 315.0
HKD1_k127_213998_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 1.04e-210 668.0
HKD1_k127_213998_1 carboxylic acid catabolic process K12661 - 4.2.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 591.0
HKD1_k127_213998_10 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000006001 203.0
HKD1_k127_213998_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000001297 225.0
HKD1_k127_213998_12 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000001219 204.0
HKD1_k127_213998_13 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000006361 199.0
HKD1_k127_213998_14 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000003365 197.0
HKD1_k127_213998_15 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000000000000000000000000000001393 164.0
HKD1_k127_213998_16 Fibronectin-binding protein - - - 0.000000000000000000000000000000000000000002662 176.0
HKD1_k127_213998_17 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000001186 159.0
HKD1_k127_213998_18 5'-nucleotidase - - - 0.000000000000000000000000000000000000008919 160.0
HKD1_k127_213998_19 positive regulation of growth rate - - - 0.000000000000000000000000001224 127.0
HKD1_k127_213998_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 574.0
HKD1_k127_213998_20 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000004689 107.0
HKD1_k127_213998_21 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000004955 95.0
HKD1_k127_213998_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000004231 81.0
HKD1_k127_213998_23 Protein of unknown function (DUF721) - - - 0.0000001297 59.0
HKD1_k127_213998_3 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 539.0
HKD1_k127_213998_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 406.0
HKD1_k127_213998_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 398.0
HKD1_k127_213998_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 349.0
HKD1_k127_213998_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007071 274.0
HKD1_k127_213998_8 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000009276 233.0
HKD1_k127_213998_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
HKD1_k127_2141941_0 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000002931 117.0
HKD1_k127_2141941_1 WD domain, G-beta repeat K22382 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006109,GO:0006111,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010498,GO:0010675,GO:0010677,GO:0010906,GO:0019222,GO:0019538,GO:0019941,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0034657,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043255,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0045721,GO:0045912,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051603,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901565,GO:1901575 - 0.00002606 52.0
HKD1_k127_2146124_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 582.0
HKD1_k127_2146124_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 436.0
HKD1_k127_2146124_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000004997 201.0
HKD1_k127_2146124_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000393 126.0
HKD1_k127_2153475_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 534.0
HKD1_k127_2153475_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 386.0
HKD1_k127_2153475_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000004177 149.0
HKD1_k127_2160537_0 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 323.0
HKD1_k127_2160537_1 phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001162 280.0
HKD1_k127_2160537_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000004216 189.0
HKD1_k127_2160537_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000006158 156.0
HKD1_k127_2160537_4 - - - - 0.00000000000000000000000001171 113.0
HKD1_k127_216212_0 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 611.0
HKD1_k127_216212_1 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 600.0
HKD1_k127_216212_2 4-phosphoerythronate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001867 282.0
HKD1_k127_216212_3 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
HKD1_k127_216212_4 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000006476 192.0
HKD1_k127_216212_5 glucuronate isomerase K01812 - 5.3.1.12 0.000000000000000000000000000000000000007251 163.0
HKD1_k127_216212_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000001029 153.0
HKD1_k127_21723_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 338.0
HKD1_k127_21723_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 312.0
HKD1_k127_21723_2 DsbA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000002372 182.0
HKD1_k127_21723_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000001316 179.0
HKD1_k127_2175400_0 Non-ribosomal peptide synthetase modules and related proteins - - - 1.447e-297 961.0
HKD1_k127_2175400_1 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 527.0
HKD1_k127_2175400_2 Glucose-methanol-choline (GMC) oxidoreductase NAD binding site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 398.0
HKD1_k127_2175400_3 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 359.0
HKD1_k127_2175400_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000003618 229.0
HKD1_k127_2180099_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 582.0
HKD1_k127_2180099_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 531.0
HKD1_k127_2180099_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 392.0
HKD1_k127_2180099_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 378.0
HKD1_k127_2180099_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 292.0
HKD1_k127_2180099_5 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004603 256.0
HKD1_k127_2180099_6 - - - - 0.00000000000000000000003576 102.0
HKD1_k127_2187260_0 oxidoreductase K00311,K00313 - 1.5.5.1 4.295e-302 936.0
HKD1_k127_2187260_1 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 524.0
HKD1_k127_2187260_2 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 440.0
HKD1_k127_2187260_3 electron transfer activity K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 398.0
HKD1_k127_2206954_0 Belongs to the transketolase family K00163 - 1.2.4.1 2.797e-240 768.0
HKD1_k127_2206954_1 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 415.0
HKD1_k127_2206954_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 405.0
HKD1_k127_2206954_3 L-fucose isomerase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004251 268.0
HKD1_k127_2206954_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001941 244.0
HKD1_k127_2206954_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000007104 122.0
HKD1_k127_2206954_6 Domain of unknown function (DUF4136) - - - 0.00000002205 63.0
HKD1_k127_2220644_0 - - - - 0.00000000000000000000000000000000000000000000000000006869 191.0
HKD1_k127_2220644_1 Transglycosylase associated protein - - - 0.0000000000000000000000000001341 116.0
HKD1_k127_2220644_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000019 105.0
HKD1_k127_2220644_3 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000003225 102.0
HKD1_k127_2220644_4 Tryptophan-rich sensory protein K05770 - - 0.00000000000000000002402 97.0
HKD1_k127_2220644_5 Protein of unknown function (DUF2490) - - - 0.00000000001644 67.0
HKD1_k127_2220644_6 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000003034 64.0
HKD1_k127_2220644_7 - - - - 0.000005121 49.0
HKD1_k127_2220644_8 PFAM IS1 transposase - - - 0.000009877 54.0
HKD1_k127_2220644_9 transposition, DNA-mediated K00558 - 2.1.1.37 0.0006279 48.0
HKD1_k127_2236623_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 320.0
HKD1_k127_2236623_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000002058 186.0
HKD1_k127_2236623_2 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000001319 169.0
HKD1_k127_2265142_0 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 368.0
HKD1_k127_2265142_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000001674 165.0
HKD1_k127_2273265_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 321.0
HKD1_k127_2273265_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 288.0
HKD1_k127_2276657_0 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0 1350.0
HKD1_k127_2276657_1 HsdM N-terminal domain K03427 - 2.1.1.72 7.153e-265 821.0
HKD1_k127_2276657_2 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 485.0
HKD1_k127_2276657_3 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003881 292.0
HKD1_k127_2276657_4 Fic/DOC family K04095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002719 246.0
HKD1_k127_2276657_5 - - - - 0.000000000000000000000000000001262 130.0
HKD1_k127_2286271_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 606.0
HKD1_k127_2286271_1 Nitrate reductase delta subunit K00373 - - 0.00002259 49.0
HKD1_k127_2300482_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 425.0
HKD1_k127_2300482_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 380.0
HKD1_k127_2300482_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 361.0
HKD1_k127_2300482_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001571 239.0
HKD1_k127_2310288_0 lipopolysaccharide transport K22110 - - 0.0 1123.0
HKD1_k127_2310288_1 choline dehydrogenase activity - - - 2.638e-263 821.0
HKD1_k127_2310288_10 Heavy metal transcriptional response regulator K07665 - - 0.000001016 57.0
HKD1_k127_2310288_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 441.0
HKD1_k127_2310288_3 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 400.0
HKD1_k127_2310288_4 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 344.0
HKD1_k127_2310288_5 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000597 221.0
HKD1_k127_2310288_6 - - - - 0.00000000000000000000000000000000000000002493 173.0
HKD1_k127_2310288_7 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000004619 132.0
HKD1_k127_2310288_9 - - - - 0.0000000004193 64.0
HKD1_k127_231277_0 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 516.0
HKD1_k127_231277_1 NAD NADP octopine nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001982 261.0
HKD1_k127_231277_2 - - - - 0.0000000000000000000000005947 109.0
HKD1_k127_231277_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000002109 69.0
HKD1_k127_2319559_0 PFAM ABC transporter transmembrane K06147 - - 1.236e-268 837.0
HKD1_k127_2319559_1 DinB family - - - 0.0000000000000000000000000000000000000000000000000000002706 198.0
HKD1_k127_2319559_2 - - - - 0.00000000000000000000000000000000000000000000000000001389 201.0
HKD1_k127_2319559_3 s1 p1 nuclease - - - 0.0000000000000000000000000000000000000000000000001675 188.0
HKD1_k127_2319559_4 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000008649 188.0
HKD1_k127_2319559_5 Protein of unknown function (DUF1501) - - - 0.000000000002716 66.0
HKD1_k127_2325751_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 3.089e-215 682.0
HKD1_k127_2325751_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 512.0
HKD1_k127_2325751_2 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 471.0
HKD1_k127_2325751_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 400.0
HKD1_k127_2325751_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003743 258.0
HKD1_k127_2325751_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000508 181.0
HKD1_k127_2325751_6 mttA/Hcf106 family K03116 - - 0.000000000000000008713 85.0
HKD1_k127_2325751_7 - - - - 0.000000000000001889 79.0
HKD1_k127_2325751_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.000000002238 69.0
HKD1_k127_2329829_0 Pfam Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 535.0
HKD1_k127_233713_0 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K15893 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 302.0
HKD1_k127_233713_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
HKD1_k127_233713_2 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000004506 124.0
HKD1_k127_233713_3 PFAM Forkhead-associated protein - - - 0.0000000000000000000000005947 109.0
HKD1_k127_2378490_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 544.0
HKD1_k127_2378490_1 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 482.0
HKD1_k127_2378490_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 281.0
HKD1_k127_2378490_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000008057 267.0
HKD1_k127_2378490_4 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000005839 154.0
HKD1_k127_2378490_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000989 103.0
HKD1_k127_2380101_0 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
HKD1_k127_2380101_1 Polysaccharide lyase family 4, domain III - - - 0.000000000000000000000000000000000000000009011 175.0
HKD1_k127_2390974_0 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575 4.2.1.8 8.275e-202 637.0
HKD1_k127_2390974_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 453.0
HKD1_k127_2390974_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 380.0
HKD1_k127_2390974_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001053 235.0
HKD1_k127_2390974_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000002276 215.0
HKD1_k127_2390974_5 Putative esterase - - - 0.000000000000000000000000000000000000005172 158.0
HKD1_k127_2405023_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1271.0
HKD1_k127_2405023_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 491.0
HKD1_k127_2405023_2 Pyruvate dehydrogenase K00898 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004740,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006090,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019538,GO:0019752,GO:0023052,GO:0030554,GO:0031974,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046777,GO:0046983,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070013,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 371.0
HKD1_k127_2405023_3 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 359.0
HKD1_k127_2405023_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000018 282.0
HKD1_k127_2405023_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000003052 147.0
HKD1_k127_2405023_6 HAD-hyrolase-like - - - 0.00000000000000000000000000000008234 133.0
HKD1_k127_2405023_7 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000001333 138.0
HKD1_k127_2405023_8 - - - - 0.00000000002749 74.0
HKD1_k127_2423306_0 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001901 253.0
HKD1_k127_2423306_1 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000001086 227.0
HKD1_k127_2423306_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000002525 184.0
HKD1_k127_2423306_3 oxidoreductase activity - - - 0.000000000000000000000005599 116.0
HKD1_k127_2436170_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 580.0
HKD1_k127_2436170_1 PFAM AMP-dependent synthetase and ligase K12429,K18660,K18661,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 574.0
HKD1_k127_2436170_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 542.0
HKD1_k127_2436170_3 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 472.0
HKD1_k127_2436170_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008927 271.0
HKD1_k127_2436170_5 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000002605 244.0
HKD1_k127_2436170_6 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000001936 199.0
HKD1_k127_2436170_7 Chorismate mutase type II - - - 0.000000000000000000009335 94.0
HKD1_k127_244048_0 Protein of unknown function (DUF1553) - - - 0.0 1164.0
HKD1_k127_244048_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K18930 - - 0.0 1106.0
HKD1_k127_244048_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001912 235.0
HKD1_k127_244048_3 Major facilitator superfamily - - - 0.000000000000000000000001135 105.0
HKD1_k127_2443081_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 443.0
HKD1_k127_2443081_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001711 266.0
HKD1_k127_2458765_0 - - - - 0.00000000000000000000000000000000000000000000000000000002568 206.0
HKD1_k127_2458765_1 PFAM GGDEF domain containing protein - - - 0.00000000239 62.0
HKD1_k127_2461754_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 293.0
HKD1_k127_2461754_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
HKD1_k127_2461754_2 Protein of unknown function (DUF3443) - - - 0.00000000000000000000000000000000000000000000002656 175.0
HKD1_k127_2461754_3 - - - - 0.000000000000000000000000000000000003666 143.0
HKD1_k127_2496409_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 312.0
HKD1_k127_2496409_1 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 318.0
HKD1_k127_2520859_0 membrane organization K07277,K09800 - - 6.008e-300 997.0
HKD1_k127_2534749_0 Transposase DDE domain group 1 - - - 0.00000000000000000000001641 109.0
HKD1_k127_2544907_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 518.0
HKD1_k127_2544907_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001771 280.0
HKD1_k127_2544907_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000001472 72.0
HKD1_k127_2544907_3 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000004287 53.0
HKD1_k127_2544907_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX - - - 0.0004827 44.0
HKD1_k127_2544907_5 short chain dehydrogenase K11170 GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0008150,GO:0008152,GO:0009893,GO:0009894,GO:0009896,GO:0010506,GO:0010508,GO:0016491,GO:0019222,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0055114,GO:0065007 - 0.0004857 43.0
HKD1_k127_2589480_0 Peptidase family M48 - - - 0.0000000000000000000000000008698 122.0
HKD1_k127_2589480_1 Sigma-54 interaction domain - - - 0.00000000005596 66.0
HKD1_k127_2594036_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 479.0
HKD1_k127_2594036_1 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 385.0
HKD1_k127_2594036_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 325.0
HKD1_k127_2594036_3 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000001272 175.0
HKD1_k127_2594036_4 InterPro IPR007367 - - - 0.000000000000000000009676 99.0
HKD1_k127_2602715_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.503e-273 864.0
HKD1_k127_2602715_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000001091 147.0
HKD1_k127_2602715_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000172 111.0
HKD1_k127_2613613_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 596.0
HKD1_k127_2613613_1 PFAM Class II aldolase K03077 - 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 312.0
HKD1_k127_2613613_2 PFAM Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000008406 205.0
HKD1_k127_2613613_3 haloacid dehalogenase-like hydrolase - GO:0000123,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031248,GO:0031974,GO:0031981,GO:0032991,GO:0036409,GO:0036410,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0070013,GO:0070775,GO:1902493,GO:1902494,GO:1990234 - 0.0000000000000000000000000000000001979 141.0
HKD1_k127_2613613_4 L-fucose isomerase, C-terminal domain - - - 0.00000000000000000002347 92.0
HKD1_k127_2613613_5 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000691 53.0
HKD1_k127_2622050_0 VWA containing CoxE family protein K09989 - - 8.775e-196 617.0
HKD1_k127_2622050_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 441.0
HKD1_k127_2622050_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 401.0
HKD1_k127_2622050_3 PFAM Cyclic nucleotide-binding domain - - - 0.0000000000000000000000000000000000000005341 153.0
HKD1_k127_2641068_0 PFAM type III restriction protein res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 601.0
HKD1_k127_2641068_1 - - - - 0.0000000000000000000000000000001434 129.0
HKD1_k127_2672094_0 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001033 260.0
HKD1_k127_2672094_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000001013 203.0
HKD1_k127_2672094_2 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000001107 164.0
HKD1_k127_2684561_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.011e-302 954.0
HKD1_k127_2684561_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 513.0
HKD1_k127_2684561_10 Universal bacterial protein YeaZ K14742 - - 0.0000000000000000000000000000000000008689 147.0
HKD1_k127_2684561_11 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000000004043 136.0
HKD1_k127_2684561_12 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000002192 139.0
HKD1_k127_2684561_13 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000001883 89.0
HKD1_k127_2684561_14 protein secretion K03116 - - 0.00000000004698 65.0
HKD1_k127_2684561_2 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 502.0
HKD1_k127_2684561_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 397.0
HKD1_k127_2684561_4 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 398.0
HKD1_k127_2684561_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 378.0
HKD1_k127_2684561_6 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000003063 207.0
HKD1_k127_2684561_7 Belongs to the UPF0403 family - - - 0.000000000000000000000000000000000000000000000002644 178.0
HKD1_k127_2684561_8 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000003937 170.0
HKD1_k127_2684561_9 DUF218 domain - - - 0.0000000000000000000000000000000000000002028 156.0
HKD1_k127_270159_0 Cytochrome c554 and c-prime - - - 4.226e-314 989.0
HKD1_k127_270159_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.253e-223 706.0
HKD1_k127_270159_10 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000001245 196.0
HKD1_k127_270159_11 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000003041 194.0
HKD1_k127_270159_12 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000003225 123.0
HKD1_k127_270159_2 ASPIC and UnbV - - - 9.598e-218 690.0
HKD1_k127_270159_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.767e-205 657.0
HKD1_k127_270159_4 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 513.0
HKD1_k127_270159_5 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 460.0
HKD1_k127_270159_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 436.0
HKD1_k127_270159_7 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 362.0
HKD1_k127_270159_8 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008268 276.0
HKD1_k127_270159_9 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000001902 235.0
HKD1_k127_2716577_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 497.0
HKD1_k127_2716577_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003313 268.0
HKD1_k127_2716577_2 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.000000000000000000000000000000000000000000000000000000001821 203.0
HKD1_k127_2716577_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000008522 181.0
HKD1_k127_2716577_4 domain protein K01179,K02238,K20276 - 3.2.1.4 0.00000000000000000000000000000000000000000006524 175.0
HKD1_k127_2716577_5 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.00000000000000001791 81.0
HKD1_k127_2716577_6 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000003796 79.0
HKD1_k127_2716577_7 Hep Hag repeat protein - - - 0.00000000000003398 79.0
HKD1_k127_2722693_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 2.062e-195 619.0
HKD1_k127_2722693_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 285.0
HKD1_k127_2722693_2 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000007842 214.0
HKD1_k127_2722693_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000007006 62.0
HKD1_k127_2725211_0 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 332.0
HKD1_k127_2725211_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000001464 150.0
HKD1_k127_2725211_2 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000001974 152.0
HKD1_k127_2725211_3 - - - - 0.00000006111 63.0
HKD1_k127_275107_0 Amino acid permease - - - 4.966e-234 750.0
HKD1_k127_275107_1 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 559.0
HKD1_k127_275107_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 380.0
HKD1_k127_275107_3 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 312.0
HKD1_k127_275107_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000137 239.0
HKD1_k127_2755019_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 481.0
HKD1_k127_2755019_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000001945 246.0
HKD1_k127_2803574_0 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 508.0
HKD1_k127_2803574_1 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 529.0
HKD1_k127_2803574_2 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 411.0
HKD1_k127_2803574_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 379.0
HKD1_k127_2803574_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001351 242.0
HKD1_k127_2803574_5 Signal transduction histidine kinase, LytS K02478 - 2.7.13.3 0.00000000000000000000000000000002543 136.0
HKD1_k127_2803574_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000004074 97.0
HKD1_k127_2804640_0 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001 245.0
HKD1_k127_2804640_1 - - - - 0.0000000000000008133 88.0
HKD1_k127_2804640_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000001186 68.0
HKD1_k127_2816418_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 1.937e-197 628.0
HKD1_k127_2816418_1 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.00000000000000000000000000000000000000000000000000000000000000006317 231.0
HKD1_k127_2816418_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000006705 57.0
HKD1_k127_281650_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 501.0
HKD1_k127_281650_1 PFAM Glycosyl transferase, group 1 K03208 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 447.0
HKD1_k127_281650_2 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 428.0
HKD1_k127_281650_3 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 426.0
HKD1_k127_281650_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 412.0
HKD1_k127_281650_5 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 407.0
HKD1_k127_281650_6 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000006821 182.0
HKD1_k127_281650_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000346 147.0
HKD1_k127_281650_8 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.00000000000000000006254 101.0
HKD1_k127_281650_9 Parallel beta-helix repeats - - - 0.000000000000877 81.0
HKD1_k127_2829918_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 511.0
HKD1_k127_2829918_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000004238 108.0
HKD1_k127_2829918_2 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000008019 68.0
HKD1_k127_2858310_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 454.0
HKD1_k127_2858310_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 377.0
HKD1_k127_2858310_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000206 205.0
HKD1_k127_2858310_3 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000001705 134.0
HKD1_k127_2860614_0 Pfam:DUF1237 K09704 - - 1.563e-201 638.0
HKD1_k127_2860614_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 392.0
HKD1_k127_2860614_10 EamA-like transporter family - - - 0.000000000000001553 83.0
HKD1_k127_2860614_2 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 379.0
HKD1_k127_2860614_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 374.0
HKD1_k127_2860614_4 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 370.0
HKD1_k127_2860614_5 ergosterol biosynthetic process K02291,K21679 - 2.5.1.32,2.5.1.99,4.2.3.156 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 356.0
HKD1_k127_2860614_6 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
HKD1_k127_2860614_7 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000002679 272.0
HKD1_k127_2860614_8 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000005415 231.0
HKD1_k127_2860614_9 spore germination - - - 0.000000000000000000000000000000005319 131.0
HKD1_k127_289929_0 ATPase associated with various cellular activities, AAA_5 K02584 - - 1.577e-215 687.0
HKD1_k127_289929_1 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006989 281.0
HKD1_k127_289929_2 OsmC-like protein - - - 0.00000000000000000000000004986 115.0
HKD1_k127_2903922_0 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000004336 183.0
HKD1_k127_2903922_1 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.00000000006578 66.0
HKD1_k127_2903922_2 Glycosyl hydrolase family 115 - - - 0.0002756 54.0
HKD1_k127_292178_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000007042 236.0
HKD1_k127_292178_1 BFD domain protein 2Fe-2S -binding domain protein K00111 - 1.1.5.3 0.000000000000000000000000000000001551 131.0
HKD1_k127_2947039_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1347.0
HKD1_k127_2947039_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 626.0
HKD1_k127_2947039_2 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 541.0
HKD1_k127_2947039_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 373.0
HKD1_k127_2947039_4 - - - - 0.0000000000000000000000000000000002488 146.0
HKD1_k127_295339_0 Membrane-bound dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 535.0
HKD1_k127_295339_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 441.0
HKD1_k127_2964802_0 PFAM transposase IS116 IS110 IS902 family - - - 3.743e-212 667.0
HKD1_k127_2964802_1 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000001667 181.0
HKD1_k127_2964802_2 Transposase K07483 - - 0.0000000000000000004981 90.0
HKD1_k127_2964802_3 heme oxygenase (decyclizing) activity - - - 0.000000000000006868 78.0
HKD1_k127_2969341_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 310.0
HKD1_k127_2969341_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 301.0
HKD1_k127_2969341_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000003809 201.0
HKD1_k127_2969341_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000008498 172.0
HKD1_k127_2975026_0 Subtilase family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000404 208.0
HKD1_k127_2975026_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000496 60.0
HKD1_k127_2982760_0 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 481.0
HKD1_k127_2982760_1 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 407.0
HKD1_k127_2997076_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 548.0
HKD1_k127_2997076_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 351.0
HKD1_k127_2997076_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003176 281.0
HKD1_k127_2997076_3 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005484 275.0
HKD1_k127_2997076_4 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000004815 147.0
HKD1_k127_2997076_5 Polysaccharide chain length determinant protein - - - 0.000000000009066 77.0
HKD1_k127_2997076_6 diguanylate cyclase - - - 0.000004771 55.0
HKD1_k127_2999328_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 368.0
HKD1_k127_2999328_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000006355 132.0
HKD1_k127_2999328_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000003875 119.0
HKD1_k127_2999328_3 -O-antigen K02847,K13009 - - 0.000000005736 60.0
HKD1_k127_3003084_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.048e-215 679.0
HKD1_k127_3007996_0 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 364.0
HKD1_k127_3007996_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 329.0
HKD1_k127_3007996_2 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 321.0
HKD1_k127_3007996_3 COG3279 Response regulator of the LytR AlgR family K02477 - - 0.0000000000000000000000000000000000000000001272 169.0
HKD1_k127_3007996_4 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0004264 51.0
HKD1_k127_3009576_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 317.0
HKD1_k127_3009576_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000005179 177.0
HKD1_k127_3014871_0 PFAM DJ-1 PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000099 253.0
HKD1_k127_3014871_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000001163 217.0
HKD1_k127_3014871_2 SMART Helix-turn-helix type 3 - - - 0.000000000000000000000002731 104.0
HKD1_k127_3014871_3 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000006447 105.0
HKD1_k127_3014871_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000004816 92.0
HKD1_k127_3014871_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000003315 56.0
HKD1_k127_3035785_0 glutamate carboxypeptidase K01301 - 3.4.17.21 1.444e-272 859.0
HKD1_k127_3035785_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 379.0
HKD1_k127_3035785_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 376.0
HKD1_k127_3035785_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000000006098 122.0
HKD1_k127_3035785_4 Carboxypeptidase regulatory-like domain - - - 0.0000000002063 67.0
HKD1_k127_3039202_0 type II and III secretion system protein K02453 - - 2.954e-240 760.0
HKD1_k127_3039202_1 - - - - 0.0000000000000000000000003417 107.0
HKD1_k127_3042355_0 Sigma-70 region 2 K03088 - - 1.761e-199 629.0
HKD1_k127_3042355_1 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 293.0
HKD1_k127_3042355_2 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000009813 180.0
HKD1_k127_3042355_3 YCII-related domain - - - 0.0000000000000000000000000000000000002035 143.0
HKD1_k127_3042355_4 RNA polymerase sigma factor K03088 - - 0.0002345 49.0
HKD1_k127_3044023_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 548.0
HKD1_k127_3044023_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001015 280.0
HKD1_k127_3044023_2 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
HKD1_k127_3058741_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 456.0
HKD1_k127_3058741_1 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 389.0
HKD1_k127_3058741_10 AI-2E family transporter - - - 0.00006219 47.0
HKD1_k127_3058741_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 375.0
HKD1_k127_3058741_3 TIGRFAM Formaldehyde dehydrogenase, glutathione-independent K00148 - 1.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 325.0
HKD1_k127_3058741_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000149 292.0
HKD1_k127_3058741_5 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002643 264.0
HKD1_k127_3058741_6 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000267 258.0
HKD1_k127_3058741_7 3-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000000001335 214.0
HKD1_k127_3058741_8 Transposase IS200 like K07491 - - 0.00000000000000000000001243 107.0
HKD1_k127_3058741_9 - - - - 0.000000209 54.0
HKD1_k127_3063957_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 536.0
HKD1_k127_3063957_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 446.0
HKD1_k127_3063957_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 421.0
HKD1_k127_3063957_3 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 292.0
HKD1_k127_3063957_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003484 247.0
HKD1_k127_3063957_5 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000001014 177.0
HKD1_k127_3063957_6 PFAM Response regulator receiver domain K07713 - - 0.000000000000000000000000000000000007677 141.0
HKD1_k127_3063957_7 Glycine cleavage H-protein - - - 0.0000000000000000000000000000007437 132.0
HKD1_k127_3063957_8 Glycine cleavage H-protein - - - 0.0000000000000000000000178 109.0
HKD1_k127_3078298_0 Protein of unknown function (DUF3626) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 391.0
HKD1_k127_3078298_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000002476 139.0
HKD1_k127_3078298_2 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000000006629 124.0
HKD1_k127_3078298_3 Transglycosylase associated protein - - - 0.000000000000000000006207 95.0
HKD1_k127_3078298_4 BON domain - - - 0.00000000000000003021 92.0
HKD1_k127_3082270_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 461.0
HKD1_k127_3082270_1 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 330.0
HKD1_k127_3082270_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007366 280.0
HKD1_k127_3082270_3 UPF0182 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009828 255.0
HKD1_k127_3088976_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000001324 178.0
HKD1_k127_3091834_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 518.0
HKD1_k127_3091834_1 Carboxypeptidase regulatory-like domain - - - 0.000000000001433 72.0
HKD1_k127_3120824_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 386.0
HKD1_k127_3120824_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 316.0
HKD1_k127_3120824_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 316.0
HKD1_k127_3120824_3 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000001442 183.0
HKD1_k127_3120824_4 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000003429 167.0
HKD1_k127_3120824_5 Lysophospholipase L1 and related - - - 0.00000000000000000000000000001536 124.0
HKD1_k127_3120824_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000001757 96.0
HKD1_k127_3120824_7 phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.000000000000000000006809 100.0
HKD1_k127_3124514_0 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 377.0
HKD1_k127_3124514_1 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003828 274.0
HKD1_k127_3124514_2 hydrolase, family 65, central catalytic - - - 0.0000000000000000000000000000388 127.0
HKD1_k127_3149433_1 phosphorelay signal transduction system K07776 - - 0.0000000000000000000000000000000000000000000003343 176.0
HKD1_k127_3149433_3 identical protein binding K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.00000000000000000000000000000000000001856 151.0
HKD1_k127_3149433_4 identical protein binding K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.00000000000000000000007044 105.0
HKD1_k127_3149433_5 Tetratricopeptide repeat - - - 0.000000000000000000000464 108.0
HKD1_k127_3150976_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.958e-275 867.0
HKD1_k127_3150976_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.435e-258 805.0
HKD1_k127_3150976_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 565.0
HKD1_k127_3150976_3 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 456.0
HKD1_k127_3150976_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000001252 138.0
HKD1_k127_3150976_5 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K00996 - 2.7.8.6 0.000000000125 71.0
HKD1_k127_3150976_6 - - - - 0.000003207 54.0
HKD1_k127_315159_0 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 304.0
HKD1_k127_315159_1 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000005762 192.0
HKD1_k127_315159_2 - - - - 0.00000000000002822 76.0
HKD1_k127_315159_3 Metallo-beta-lactamase superfamily - - - 0.000002433 60.0
HKD1_k127_3156213_0 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 382.0
HKD1_k127_3156213_1 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 383.0
HKD1_k127_3156213_2 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000359 270.0
HKD1_k127_3157631_0 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 473.0
HKD1_k127_3157631_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 347.0
HKD1_k127_3157631_2 Planctomycete cytochrome C - - - 0.000000002439 61.0
HKD1_k127_3169751_0 gtp cyclohydrolase K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000074 258.0
HKD1_k127_3169751_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003416 257.0
HKD1_k127_3169751_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 257.0
HKD1_k127_3169751_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000005649 135.0
HKD1_k127_3169751_4 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000002294 96.0
HKD1_k127_3169751_5 Putative adhesin - - - 0.000000000000000000693 96.0
HKD1_k127_3169751_6 - - - - 0.000000000001409 78.0
HKD1_k127_3175759_0 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000001321 117.0
HKD1_k127_3175759_1 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.000000000000991 80.0
HKD1_k127_3175803_0 PFAM glycosyl transferase, family 51 K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 454.0
HKD1_k127_3175803_1 nuclear chromosome segregation K02004 - - 0.00000000003237 77.0
HKD1_k127_3177801_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000004434 212.0
HKD1_k127_3177801_1 Histidine kinase - - - 0.0000000000000000000000000000000000004756 154.0
HKD1_k127_3185439_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 539.0
HKD1_k127_3185439_1 - - - - 0.00000000000000000000000000003198 125.0
HKD1_k127_3185439_2 PFAM O-methyltransferase - - - 0.000000000000000000000000001089 121.0
HKD1_k127_3185439_3 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000003573 118.0
HKD1_k127_3185439_4 Protein conserved in bacteria K09981 - - 0.0000000000000000000000000406 109.0
HKD1_k127_3185439_5 Exopolysaccharide synthesis, ExoD - - - 0.00005664 47.0
HKD1_k127_3185439_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000368 49.0
HKD1_k127_3186282_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000001941 244.0
HKD1_k127_3186282_1 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000746 165.0
HKD1_k127_3196059_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 368.0
HKD1_k127_3196059_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 382.0
HKD1_k127_3196059_2 - - - - 0.000000000000000000007248 100.0
HKD1_k127_3202111_0 Protein of unknown function (DUF1553) - - - 2.022e-316 1000.0
HKD1_k127_3202111_1 Protein of unknown function (DUF1501) - - - 2.859e-235 735.0
HKD1_k127_3202111_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 477.0
HKD1_k127_3202111_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 367.0
HKD1_k127_3202111_4 Psort location Cytoplasmic, score K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 370.0
HKD1_k127_3202111_5 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006146 278.0
HKD1_k127_3202111_6 - - - - 0.00000000000000000000003286 106.0
HKD1_k127_3202111_7 Tetratricopeptide repeat - - - 0.00000000000001518 85.0
HKD1_k127_321054_0 hydrolase family, 3 K05349 - 3.2.1.21 0.0 1053.0
HKD1_k127_321054_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.974e-290 908.0
HKD1_k127_321054_10 Surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 419.0
HKD1_k127_321054_11 Domain of unknown function (DUF4432) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 392.0
HKD1_k127_321054_12 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 417.0
HKD1_k127_321054_13 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 370.0
HKD1_k127_321054_14 glycyl-radical enzyme activating protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 289.0
HKD1_k127_321054_15 Transporter, major facilitator family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007568 251.0
HKD1_k127_321054_16 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000196 229.0
HKD1_k127_321054_17 catechol 1,2-dioxygenase - - - 0.0000000000000000000000000000000000000000002237 163.0
HKD1_k127_321054_18 Rdx family K07401 - - 0.00000000000000000000000000000000000000002938 153.0
HKD1_k127_321054_19 - - - - 0.00000000000000000000000000000000000000006475 171.0
HKD1_k127_321054_2 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.336e-267 839.0
HKD1_k127_321054_20 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000001163 156.0
HKD1_k127_321054_21 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000008819 153.0
HKD1_k127_321054_22 Protein involved in outer membrane biogenesis K07289 - - 0.000000000000000000000000000000000000623 162.0
HKD1_k127_321054_23 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002308 130.0
HKD1_k127_321054_24 intracellular protein transport - - - 0.00000000000000000000000000000003141 146.0
HKD1_k127_321054_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000006076 116.0
HKD1_k127_321054_26 PFAM Transglycosylase SLT domain K08307 - - 0.00000000000000000000000009157 119.0
HKD1_k127_321054_27 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000007406 101.0
HKD1_k127_321054_28 Polymer-forming cytoskeletal - - - 0.0000000000000000000004577 101.0
HKD1_k127_321054_29 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000002333 102.0
HKD1_k127_321054_3 Pyruvate formate lyase-like - - - 4.502e-245 778.0
HKD1_k127_321054_30 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000001942 95.0
HKD1_k127_321054_31 negative regulation of transcription, DNA-templated - - - 0.000000000000000004994 91.0
HKD1_k127_321054_32 Domain of unknown function (DUF4388) - - - 0.00000000351 70.0
HKD1_k127_321054_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.229e-240 769.0
HKD1_k127_321054_5 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 620.0
HKD1_k127_321054_6 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 505.0
HKD1_k127_321054_7 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 446.0
HKD1_k127_321054_8 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 432.0
HKD1_k127_321054_9 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 439.0
HKD1_k127_3217761_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.233e-215 683.0
HKD1_k127_3217761_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 423.0
HKD1_k127_3217761_10 - - - - 0.00007062 45.0
HKD1_k127_3217761_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 414.0
HKD1_k127_3217761_3 COGs COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000818 280.0
HKD1_k127_3217761_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000003288 239.0
HKD1_k127_3217761_5 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000018 232.0
HKD1_k127_3217761_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000528 226.0
HKD1_k127_3217761_7 Regulatory protein - - - 0.0000000000000000000000000001235 121.0
HKD1_k127_3217761_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000002512 63.0
HKD1_k127_3217761_9 Histidine kinase-like ATPases - - - 0.0000002405 54.0
HKD1_k127_3226487_0 GMC oxidoreductase - - - 1.909e-209 663.0
HKD1_k127_3226487_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 552.0
HKD1_k127_3226487_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 366.0
HKD1_k127_3226487_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001248 259.0
HKD1_k127_3226487_4 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000723 257.0
HKD1_k127_3226487_5 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
HKD1_k127_3226487_6 - - - - 0.000000000000000000000000000000000003699 143.0
HKD1_k127_3226487_7 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000007559 114.0
HKD1_k127_3226487_8 protein conserved in bacteria - - - 0.00000000000000003837 90.0
HKD1_k127_3232563_0 Protein of unknown function (DUF1501) - - - 9.097e-216 678.0
HKD1_k127_3232563_1 Protein of unknown function (DUF1553) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 436.0
HKD1_k127_3232563_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000009375 154.0
HKD1_k127_3232902_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 305.0
HKD1_k127_3232902_1 Methyltransferase domain K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000006477 245.0
HKD1_k127_3232902_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
HKD1_k127_3232902_3 dCMP deaminase activity K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000005569 199.0
HKD1_k127_3235778_0 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002559 265.0
HKD1_k127_3235778_1 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000001586 117.0
HKD1_k127_3268680_0 Aldo Keto reductase K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 449.0
HKD1_k127_3268680_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 342.0
HKD1_k127_3268680_2 High-affinity nickel-transport protein K08970 - - 0.0000000001824 64.0
HKD1_k127_3272981_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 523.0
HKD1_k127_3272981_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 478.0
HKD1_k127_3272981_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000003572 110.0
HKD1_k127_3274973_0 arylformamidase activity K00036,K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.363,1.1.1.49,3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 603.0
HKD1_k127_3274973_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 334.0
HKD1_k127_3280089_0 Dehydrogenase K00117 - 1.1.5.2 1.056e-206 650.0
HKD1_k127_3280089_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000001483 143.0
HKD1_k127_3282107_0 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 392.0
HKD1_k127_3282107_1 transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000518 242.0
HKD1_k127_3282107_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000002915 132.0
HKD1_k127_3282107_3 - - - - 0.00000000000000000000000002666 119.0
HKD1_k127_3287995_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000002647 169.0
HKD1_k127_3287995_1 protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000004747 128.0
HKD1_k127_3287995_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000741 111.0
HKD1_k127_3287995_3 AntiSigma factor - - - 0.00000000000001229 83.0
HKD1_k127_3288845_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000017 104.0
HKD1_k127_3288845_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000003194 73.0
HKD1_k127_3288845_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000002685 68.0
HKD1_k127_3288994_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 6.811e-250 784.0
HKD1_k127_3288994_1 xylose isomerase activity K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 425.0
HKD1_k127_3288994_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005556 255.0
HKD1_k127_3288994_3 PFAM Xylose isomerase domain protein TIM barrel K06605 - - 0.000000000000000000000000000000000000000001557 158.0
HKD1_k127_3288994_4 PFAM Membrane protein of K08972 - - 0.00000000000000000001342 97.0
HKD1_k127_3288994_5 myo-inosose-2 dehydratase activity K10709 - - 0.000000005926 66.0
HKD1_k127_3291971_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 308.0
HKD1_k127_3291971_1 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000242 183.0
HKD1_k127_3291971_2 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0006591 45.0
HKD1_k127_3292749_0 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006463 237.0
HKD1_k127_3292749_1 - - - - 0.00000000000000000000001926 100.0
HKD1_k127_3312571_0 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 462.0
HKD1_k127_3312571_1 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000000000000009554 142.0
HKD1_k127_3312571_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000000001175 139.0
HKD1_k127_3325050_0 class II (D K K01893 - 6.1.1.22 3.698e-201 634.0
HKD1_k127_3325050_1 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000001913 187.0
HKD1_k127_3325050_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000005604 167.0
HKD1_k127_3329959_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 445.0
HKD1_k127_3329959_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 374.0
HKD1_k127_3329959_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 296.0
HKD1_k127_3329959_3 COGs COG4328 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000003064 233.0
HKD1_k127_3329959_4 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000000006038 226.0
HKD1_k127_3333358_0 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 452.0
HKD1_k127_3333358_1 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002091 287.0
HKD1_k127_3333358_2 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003597 263.0
HKD1_k127_3333358_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000002466 165.0
HKD1_k127_3333358_4 peptidase S9 - - - 0.000000000000000000000000000000666 126.0
HKD1_k127_3333358_5 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000002427 89.0
HKD1_k127_3336553_0 Belongs to the aldehyde dehydrogenase family K00130,K00135,K00146,K22187 - 1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79,1.2.1.8 1.009e-253 790.0
HKD1_k127_3336553_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 542.0
HKD1_k127_3336553_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 451.0
HKD1_k127_3336553_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 311.0
HKD1_k127_3336553_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 289.0
HKD1_k127_3336553_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000003911 267.0
HKD1_k127_3336553_6 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
HKD1_k127_3336553_7 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
HKD1_k127_3336553_8 redox protein, regulator of disulfide bond formation - - - 0.0000007594 58.0
HKD1_k127_3337345_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 392.0
HKD1_k127_3337345_1 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 347.0
HKD1_k127_3337345_2 SAD/SRA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000063 276.0
HKD1_k127_3337345_3 MaoC like domain - - - 0.0000000004979 63.0
HKD1_k127_3358031_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000002964 160.0
HKD1_k127_3358031_1 Radical SAM - - - 0.00000001307 60.0
HKD1_k127_3362048_0 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 333.0
HKD1_k127_3362048_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 311.0
HKD1_k127_3362048_10 - - - - 0.000003571 52.0
HKD1_k127_3362048_2 PFAM Isocitrate lyase family K03417,K20454 - 4.1.3.30,4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002426 283.0
HKD1_k127_3362048_3 transmembrane transporter activity K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000008312 246.0
HKD1_k127_3362048_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000001161 217.0
HKD1_k127_3362048_5 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000166 220.0
HKD1_k127_3362048_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000003999 210.0
HKD1_k127_3362048_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000003613 185.0
HKD1_k127_3362048_8 Hfq protein - - - 0.000000000000000000000000000006067 122.0
HKD1_k127_3362048_9 Belongs to the UPF0235 family K09131 - - 0.000000000001081 73.0
HKD1_k127_3371772_0 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000005717 249.0
HKD1_k127_3371772_1 Glycosyl transferase, family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000000000002715 230.0
HKD1_k127_3371772_2 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001003 233.0
HKD1_k127_3371772_3 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000001554 220.0
HKD1_k127_3371772_4 pilus assembly protein PilW K02672 - - 0.00001442 55.0
HKD1_k127_3371772_5 - - - - 0.0001985 53.0
HKD1_k127_3380533_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 610.0
HKD1_k127_3380533_1 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 359.0
HKD1_k127_3380533_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000007529 211.0
HKD1_k127_3380533_3 Peptidase M16 - - - 0.00000000000004102 76.0
HKD1_k127_3380533_4 Predicted membrane protein (DUF2085) - - - 0.000001824 57.0
HKD1_k127_3385475_0 2-hydroxyglutaryl-CoA dehydratase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 314.0
HKD1_k127_3385475_1 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002982 273.0
HKD1_k127_3385475_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000005977 241.0
HKD1_k127_3385475_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000002735 148.0
HKD1_k127_3393850_0 Protein of unknown function (DUF1549) - - - 2.975e-213 684.0
HKD1_k127_3393850_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000005616 209.0
HKD1_k127_3403698_0 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 477.0
HKD1_k127_3403698_1 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 432.0
HKD1_k127_3403698_10 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 297.0
HKD1_k127_3403698_11 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004143 278.0
HKD1_k127_3403698_12 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005171 269.0
HKD1_k127_3403698_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002976 271.0
HKD1_k127_3403698_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001075 257.0
HKD1_k127_3403698_15 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000007547 216.0
HKD1_k127_3403698_16 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000005569 203.0
HKD1_k127_3403698_17 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000001426 171.0
HKD1_k127_3403698_18 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000007241 161.0
HKD1_k127_3403698_19 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000006201 157.0
HKD1_k127_3403698_2 COGs COG0673 dehydrogenase and related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 368.0
HKD1_k127_3403698_20 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000005913 155.0
HKD1_k127_3403698_22 deoxyhypusine monooxygenase activity K05384 - - 0.000000002696 69.0
HKD1_k127_3403698_23 Protein of unknown function (DUF3106) - - - 0.0000001659 60.0
HKD1_k127_3403698_24 integral membrane protein - - - 0.0000004067 59.0
HKD1_k127_3403698_25 GAF domain K02584 - - 0.00008977 49.0
HKD1_k127_3403698_26 - - - - 0.0005437 49.0
HKD1_k127_3403698_3 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 352.0
HKD1_k127_3403698_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 357.0
HKD1_k127_3403698_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 352.0
HKD1_k127_3403698_6 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 335.0
HKD1_k127_3403698_7 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 330.0
HKD1_k127_3403698_8 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 308.0
HKD1_k127_3403698_9 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 312.0
HKD1_k127_3435479_0 PFAM Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 432.0
HKD1_k127_3442318_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 467.0
HKD1_k127_3452950_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 312.0
HKD1_k127_3452950_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000001784 75.0
HKD1_k127_3453747_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007292 297.0
HKD1_k127_3453747_1 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000000000000001793 186.0
HKD1_k127_3459030_0 GMC oxidoreductase - - - 1.007e-290 900.0
HKD1_k127_3459030_1 Fumarylacetoacetate (FAA) hydrolase family K16164 - 3.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000002102 236.0
HKD1_k127_3459030_2 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000002919 105.0
HKD1_k127_3459030_3 phosphohydrolase K06950 - - 0.0000000000000001699 81.0
HKD1_k127_3459030_4 CTP synthase K01937 - 6.3.4.2 0.0000000000008017 68.0
HKD1_k127_3478379_0 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 486.0
HKD1_k127_3478379_1 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 436.0
HKD1_k127_3478379_2 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 345.0
HKD1_k127_3478379_3 response to copper ion K01187,K16915 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 301.0
HKD1_k127_3478379_4 cellulase activity - - - 0.0000000000000000006842 92.0
HKD1_k127_3479019_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.567e-212 668.0
HKD1_k127_3479019_1 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 520.0
HKD1_k127_3479019_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000006003 162.0
HKD1_k127_3484104_0 Protein of unknown function (DUF1549) - - - 0.0 1152.0
HKD1_k127_3484104_1 Protein of unknown function (DUF1501) - - - 8.7e-239 746.0
HKD1_k127_3484104_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000002344 219.0
HKD1_k127_3484104_3 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000003847 158.0
HKD1_k127_3501769_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 297.0
HKD1_k127_3501769_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000004076 223.0
HKD1_k127_3501769_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000002494 174.0
HKD1_k127_3501769_3 Rhodanese Homology Domain - - - 0.000000000000003267 84.0
HKD1_k127_3501769_4 methylamine metabolic process - - - 0.000000000000008147 82.0
HKD1_k127_3506198_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 512.0
HKD1_k127_3506198_1 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007083 286.0
HKD1_k127_3507347_0 glycogen phosphorylase activity K00688,K00691 - 2.4.1.1,2.4.1.8 1.2e-237 751.0
HKD1_k127_3507347_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 3.667e-198 629.0
HKD1_k127_3507347_2 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000002796 253.0
HKD1_k127_3507347_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000004779 129.0
HKD1_k127_3515733_0 Voltage gated chloride channel - - - 5.232e-216 686.0
HKD1_k127_3515733_1 P-loop ATPase protein family K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 566.0
HKD1_k127_3515733_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 471.0
HKD1_k127_3515733_3 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 455.0
HKD1_k127_3515733_4 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 374.0
HKD1_k127_3515733_5 Nucleotidyl transferase K00966,K00973 - 2.7.7.13,2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000008542 245.0
HKD1_k127_3515733_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000002967 199.0
HKD1_k127_3515733_7 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000002987 169.0
HKD1_k127_3515733_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000004776 153.0
HKD1_k127_3515733_9 and related - - - 0.00000000000000000000000001103 112.0
HKD1_k127_3516622_0 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 355.0
HKD1_k127_3516622_1 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 353.0
HKD1_k127_3516622_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
HKD1_k127_3516622_3 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000001199 194.0
HKD1_k127_3516622_4 Trm112p-like protein K09791 - - 0.0000000000000000000009879 94.0
HKD1_k127_3516622_5 - - - - 0.0000000004712 67.0
HKD1_k127_3516622_6 AntiSigma factor - - - 0.00001262 49.0
HKD1_k127_351949_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 5.756e-270 843.0
HKD1_k127_351949_1 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 302.0
HKD1_k127_351949_2 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000002011 171.0
HKD1_k127_3525379_0 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 506.0
HKD1_k127_3525379_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 359.0
HKD1_k127_3525379_2 Major facilitator superfamily K06610,K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 333.0
HKD1_k127_3525379_3 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000001304 177.0
HKD1_k127_3530394_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 588.0
HKD1_k127_3530394_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 490.0
HKD1_k127_3530394_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000004154 118.0
HKD1_k127_3530394_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000001628 118.0
HKD1_k127_3530394_12 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000569 94.0
HKD1_k127_3530394_13 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.000000000000001695 81.0
HKD1_k127_3530394_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 465.0
HKD1_k127_3530394_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 429.0
HKD1_k127_3530394_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 319.0
HKD1_k127_3530394_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000002441 219.0
HKD1_k127_3530394_6 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000001562 214.0
HKD1_k127_3530394_7 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000004727 176.0
HKD1_k127_3530394_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000002362 161.0
HKD1_k127_3530394_9 - - - - 0.000000000000000000000000000000000003149 145.0
HKD1_k127_3538619_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.514e-215 674.0
HKD1_k127_3538619_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 550.0
HKD1_k127_3538619_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 489.0
HKD1_k127_3538619_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 483.0
HKD1_k127_3538619_4 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 418.0
HKD1_k127_3538619_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000004614 101.0
HKD1_k127_3540493_0 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000702 260.0
HKD1_k127_3540493_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000001122 174.0
HKD1_k127_3540493_2 - - - - 0.000000000000002859 78.0
HKD1_k127_3548622_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 5.129e-211 662.0
HKD1_k127_3548622_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 492.0
HKD1_k127_3548622_2 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 484.0
HKD1_k127_3548622_3 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 460.0
HKD1_k127_3548622_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001794 257.0
HKD1_k127_3548622_5 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000005529 86.0
HKD1_k127_3548622_6 YwiC-like protein - - - 0.0000000000000003823 89.0
HKD1_k127_355429_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 7.819e-245 775.0
HKD1_k127_355429_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 1.393e-202 640.0
HKD1_k127_355429_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 545.0
HKD1_k127_355429_3 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 366.0
HKD1_k127_355429_4 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000002918 206.0
HKD1_k127_355429_5 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000003892 201.0
HKD1_k127_355429_6 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000000000000005131 158.0
HKD1_k127_355429_7 - - - - 0.000000000000000000000000000000000001176 149.0
HKD1_k127_355429_9 - - - - 0.000000000000000000000008177 108.0
HKD1_k127_3569055_0 Glycoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 623.0
HKD1_k127_3569055_1 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 357.0
HKD1_k127_3569055_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 301.0
HKD1_k127_3576458_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
HKD1_k127_3576458_1 YbbR-like protein - - - 0.0000000000000000000000000000001272 131.0
HKD1_k127_3576458_2 - - - - 0.00000000000000005448 80.0
HKD1_k127_3581233_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 496.0
HKD1_k127_3581233_1 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.00000000000000000000000000000000175 138.0
HKD1_k127_3584435_0 - - - - 2.535e-252 804.0
HKD1_k127_3584435_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100,K03444,K08138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 319.0
HKD1_k127_3584435_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000001412 196.0
HKD1_k127_3584435_3 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.0000000000000000000000000000000000000000000194 171.0
HKD1_k127_3584435_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000007529 163.0
HKD1_k127_3600055_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 501.0
HKD1_k127_3600055_1 COG0845 membrane-fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 430.0
HKD1_k127_3600055_2 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 339.0
HKD1_k127_3600055_3 Peptidase C39 family K12541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 340.0
HKD1_k127_3600055_4 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 332.0
HKD1_k127_3600055_5 Outer membrane component of multidrug efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 340.0
HKD1_k127_3600055_6 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000002332 61.0
HKD1_k127_3600055_7 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00009515 50.0
HKD1_k127_3610571_0 Non-ribosomal peptide synthetase modules and related proteins - - - 1.31e-251 812.0
HKD1_k127_3610571_1 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000000000002183 189.0
HKD1_k127_3610571_2 domain protein - - - 0.000000000000004009 80.0
HKD1_k127_3613950_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 490.0
HKD1_k127_3613950_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 449.0
HKD1_k127_3613950_2 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 439.0
HKD1_k127_3613950_4 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002206 258.0
HKD1_k127_3613950_5 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000114 240.0
HKD1_k127_3613950_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000002873 231.0
HKD1_k127_3613950_7 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000003138 234.0
HKD1_k127_3613950_8 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000006682 142.0
HKD1_k127_3613950_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001059 115.0
HKD1_k127_3614372_0 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 386.0
HKD1_k127_3614372_1 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 293.0
HKD1_k127_3614372_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000000537 141.0
HKD1_k127_3621741_0 Domain of unknown function (DUF4185) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 381.0
HKD1_k127_3621741_1 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 334.0
HKD1_k127_3621741_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009142 276.0
HKD1_k127_3621741_3 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000003741 199.0
HKD1_k127_3626241_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000001247 160.0
HKD1_k127_3626241_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000002799 136.0
HKD1_k127_3626241_2 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.00000000000000000000000000453 117.0
HKD1_k127_3626241_3 - - - - 0.0000000000000000000001476 102.0
HKD1_k127_3626241_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000302 94.0
HKD1_k127_3627040_0 Alpha beta hydrolase K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000004707 169.0
HKD1_k127_3627040_1 HicB family K18843 - - 0.0000000000000000009414 90.0
HKD1_k127_3627040_2 - - - - 0.000005437 53.0
HKD1_k127_3627664_0 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 544.0
HKD1_k127_3645447_0 - - - - 0.0000000000000000000000000000000000000377 164.0
HKD1_k127_3645447_1 ATP ADP translocase K03301 - - 0.0000000001372 68.0
HKD1_k127_3647463_0 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 540.0
HKD1_k127_3647463_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000379 204.0
HKD1_k127_3647463_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000267 72.0
HKD1_k127_3649134_0 PFAM Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 486.0
HKD1_k127_3649134_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000219 246.0
HKD1_k127_3649134_2 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000001942 226.0
HKD1_k127_3649134_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000003323 186.0
HKD1_k127_3649134_4 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000008328 106.0
HKD1_k127_3649134_5 Rhodanese Homology Domain - - - 0.000000000000000003924 89.0
HKD1_k127_3651937_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1142.0
HKD1_k127_3651937_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 507.0
HKD1_k127_3651937_10 Bacterial membrane protein YfhO - - - 0.000000000000006994 89.0
HKD1_k127_3651937_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 484.0
HKD1_k127_3651937_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 337.0
HKD1_k127_3651937_4 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005784 255.0
HKD1_k127_3651937_5 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000036 231.0
HKD1_k127_3651937_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000007969 206.0
HKD1_k127_3651937_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000004947 130.0
HKD1_k127_3651937_8 peptidyl-tyrosine sulfation - - - 0.00000000000000002849 94.0
HKD1_k127_3651937_9 ABC-2 family transporter protein K09696 - - 0.000000000000002723 85.0
HKD1_k127_3665281_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 585.0
HKD1_k127_3665281_1 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
HKD1_k127_3665281_2 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005678 275.0
HKD1_k127_3671708_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 306.0
HKD1_k127_3671708_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000002651 150.0
HKD1_k127_3671708_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000001565 144.0
HKD1_k127_3671708_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000004399 76.0
HKD1_k127_3679845_0 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 451.0
HKD1_k127_3679845_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 401.0
HKD1_k127_3679845_2 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 389.0
HKD1_k127_3679845_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001611 281.0
HKD1_k127_3679845_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000987 288.0
HKD1_k127_3679845_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000005543 130.0
HKD1_k127_3679845_6 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000002904 139.0
HKD1_k127_3679845_7 -O-antigen - - - 0.000000000000000000000000001284 117.0
HKD1_k127_3679845_8 Glycosyl transferases group 1 - - - 0.000000000000000000095 93.0
HKD1_k127_3684165_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000002889 104.0
HKD1_k127_3696504_0 Beta-lactamase - - - 2.709e-254 807.0
HKD1_k127_3696504_1 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 334.0
HKD1_k127_3696504_2 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 284.0
HKD1_k127_3696504_3 transglycosylase K08309 - - 0.000139 52.0
HKD1_k127_3696778_0 Erythromycin esterase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000008296 208.0
HKD1_k127_3696778_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000008768 198.0
HKD1_k127_3696778_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000004889 195.0
HKD1_k127_3696778_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000001286 173.0
HKD1_k127_3696778_4 Dienelactone hydrolase family - - - 0.0000000005226 60.0
HKD1_k127_3698809_0 Sodium:solute symporter family - - - 2.245e-303 938.0
HKD1_k127_3698809_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 480.0
HKD1_k127_3698809_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000006175 105.0
HKD1_k127_3698809_3 Protein of unknown function (DUF1501) - - - 0.0000000002601 61.0
HKD1_k127_3709370_0 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000001152 208.0
HKD1_k127_3709370_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000002362 152.0
HKD1_k127_3709370_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000004838 135.0
HKD1_k127_3710290_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000191 281.0
HKD1_k127_3710290_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001566 277.0
HKD1_k127_3710290_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000001429 197.0
HKD1_k127_3710290_3 PFAM DSBA-like thioredoxin domain - - - 0.000000000000000000000000003079 121.0
HKD1_k127_3710290_4 FAD binding domain - - - 0.000000000000000000000004627 106.0
HKD1_k127_3710290_5 Vitamin K epoxide reductase - - - 0.000000000000009873 80.0
HKD1_k127_3710290_6 general secretion pathway protein G K02456 - - 0.000706 49.0
HKD1_k127_3734826_0 Glycogen debranching enzyme K01193 - 3.2.1.26 1.159e-256 812.0
HKD1_k127_3734826_1 Serine carboxypeptidase - - - 4.784e-198 631.0
HKD1_k127_3734826_2 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 415.0
HKD1_k127_3734826_3 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 349.0
HKD1_k127_3734826_4 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000003399 119.0
HKD1_k127_3737779_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 425.0
HKD1_k127_3747097_0 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000782 256.0
HKD1_k127_3764435_0 cobalamin-transporting ATPase activity K02014,K16092 - - 3.892e-210 673.0
HKD1_k127_3764435_1 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000003414 243.0
HKD1_k127_3764435_2 - - - - 0.00000000000002011 75.0
HKD1_k127_3764435_3 ABC transporter K02013 - 3.6.3.34 0.00000005622 55.0
HKD1_k127_3778010_0 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 572.0
HKD1_k127_3778010_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 337.0
HKD1_k127_3778010_2 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001344 227.0
HKD1_k127_3778010_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000001473 199.0
HKD1_k127_3778010_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000001167 174.0
HKD1_k127_3778010_5 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000000000000000000876 171.0
HKD1_k127_3778010_6 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000001363 169.0
HKD1_k127_3778010_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000007613 128.0
HKD1_k127_3794213_0 Carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 574.0
HKD1_k127_3794213_1 myo-inosose-2 dehydratase activity K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 452.0
HKD1_k127_3794213_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 442.0
HKD1_k127_3794213_3 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 434.0
HKD1_k127_3794213_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 336.0
HKD1_k127_3794213_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000001808 220.0
HKD1_k127_3794213_6 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000001315 161.0
HKD1_k127_3794213_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000004575 144.0
HKD1_k127_3794213_8 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000005277 117.0
HKD1_k127_3797674_0 OPT oligopeptide transporter protein - - - 1.409e-288 899.0
HKD1_k127_3797674_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 481.0
HKD1_k127_3797674_2 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003689 279.0
HKD1_k127_3797674_3 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000001823 165.0
HKD1_k127_3797674_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000002463 126.0
HKD1_k127_3797674_5 Zincin-like metallopeptidase - - - 0.000000000000000000003204 97.0
HKD1_k127_3797674_6 Methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.000000000000005631 78.0
HKD1_k127_3801864_0 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 484.0
HKD1_k127_3801864_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 413.0
HKD1_k127_3801864_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000177 98.0
HKD1_k127_3801864_3 PFAM Radical SAM K22226 - - 0.000000000000000002161 97.0
HKD1_k127_3809709_0 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 316.0
HKD1_k127_3809709_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 303.0
HKD1_k127_3809709_2 PFAM 3-demethylubiquinone-9 K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006329 278.0
HKD1_k127_3809709_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000001034 186.0
HKD1_k127_3809709_4 - - - - 0.0000000000000000000000000000000000000000005145 160.0
HKD1_k127_3809709_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.000000000000000000000000000000000000001572 149.0
HKD1_k127_3809709_6 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000995 100.0
HKD1_k127_3809709_7 Glyoxalase-like domain K07032 - - 0.000000000000000002635 85.0
HKD1_k127_3809709_8 Belongs to the dihydrofolate reductase family - - - 0.000000000002877 68.0
HKD1_k127_3826355_0 - - - - 0.00000000000000000000000000000000000000000000000000000000001809 213.0
HKD1_k127_3826355_1 amine dehydrogenase activity K14647,K21449 - - 0.000000000000002235 90.0
HKD1_k127_3826355_2 Cysteine-rich secretory protein family - - - 0.00000000000224 75.0
HKD1_k127_3826703_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 319.0
HKD1_k127_3826703_1 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000005938 170.0
HKD1_k127_3826703_2 DNA integration K14059 - - 0.00000000015 68.0
HKD1_k127_3827550_0 Heat shock 70 kDa protein K04043 - - 1.405e-311 964.0
HKD1_k127_3827550_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 386.0
HKD1_k127_3827550_2 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000001732 234.0
HKD1_k127_3827550_3 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000000000000000000000007015 151.0
HKD1_k127_3827743_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1313.0
HKD1_k127_3827743_1 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 433.0
HKD1_k127_3827743_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 334.0
HKD1_k127_3827743_3 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.0000000000000000000000000000000000000000000000000002504 198.0
HKD1_k127_3827743_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000004568 156.0
HKD1_k127_3827743_5 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000009444 153.0
HKD1_k127_3833760_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 4.857e-231 730.0
HKD1_k127_3833760_1 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000003584 180.0
HKD1_k127_3833760_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000000000000000001434 129.0
HKD1_k127_3853554_0 Polysaccharide deacetylase - - - 0.0 1223.0
HKD1_k127_3853554_1 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 2.566e-293 913.0
HKD1_k127_3853554_10 endoribonuclease L-PSP - - - 0.000000000000005192 75.0
HKD1_k127_3853554_11 Domain of unknown function (DUF4412) - - - 0.000000000003839 76.0
HKD1_k127_3853554_12 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.00000000005237 72.0
HKD1_k127_3853554_13 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.0006291 42.0
HKD1_k127_3853554_14 Glycosyl transferase family 21 K00786 - - 0.0007745 42.0
HKD1_k127_3853554_2 Phosphate acyltransferases K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 617.0
HKD1_k127_3853554_3 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 546.0
HKD1_k127_3853554_4 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 524.0
HKD1_k127_3853554_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 447.0
HKD1_k127_3853554_6 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 434.0
HKD1_k127_3853554_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 385.0
HKD1_k127_3853554_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 347.0
HKD1_k127_3853554_9 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000001206 210.0
HKD1_k127_3854607_0 Cytochrome c - - - 0.0 1318.0
HKD1_k127_3854607_1 Protein of unknown function (DUF1501) - - - 2.233e-247 771.0
HKD1_k127_3854607_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 476.0
HKD1_k127_3854607_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000006038 222.0
HKD1_k127_3854607_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000001614 161.0
HKD1_k127_3888420_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 490.0
HKD1_k127_3888420_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001489 276.0
HKD1_k127_393024_0 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000001763 180.0
HKD1_k127_393024_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000001787 127.0
HKD1_k127_393024_2 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid K03328,K16695 - - 0.000000000000000001753 94.0
HKD1_k127_393024_3 Methicillin resistance protein - - - 0.00002278 56.0
HKD1_k127_3930907_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 482.0
HKD1_k127_3930907_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 316.0
HKD1_k127_3930907_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000001026 177.0
HKD1_k127_3930907_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000001496 123.0
HKD1_k127_3930907_4 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000004882 80.0
HKD1_k127_3977992_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 383.0
HKD1_k127_3977992_1 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 295.0
HKD1_k127_3977992_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000494 272.0
HKD1_k127_3977992_3 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000003591 151.0
HKD1_k127_3999724_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 3.502e-219 698.0
HKD1_k127_3999724_1 modulates the activities of several proteins which are inactive in their K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004001 265.0
HKD1_k127_3999724_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000000001049 175.0
HKD1_k127_4018718_0 protein transport across the cell outer membrane K02453,K03219 - - 0.00000000000000000001565 102.0
HKD1_k127_4018718_1 fimbrial assembly K02461 - - 0.00000001399 66.0
HKD1_k127_4018718_2 General secretion pathway protein M K02462 - - 0.0005593 49.0
HKD1_k127_4018845_0 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 557.0
HKD1_k127_4018845_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 520.0
HKD1_k127_4018845_2 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 329.0
HKD1_k127_4018845_3 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 319.0
HKD1_k127_4018845_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 278.0
HKD1_k127_4018845_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000002406 203.0
HKD1_k127_4018845_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000007456 93.0
HKD1_k127_4018845_7 Tetratricopeptide repeat - - - 0.00000000000000000004907 104.0
HKD1_k127_4019554_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062,K22397 - 3.5.4.22,4.1.2.28,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000879 233.0
HKD1_k127_4019554_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000212 171.0
HKD1_k127_4025293_0 FCD - - - 0.0000000000000000000000000000000000000000000000007458 184.0
HKD1_k127_4025293_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000264 113.0
HKD1_k127_4025293_2 Creatinase/Prolidase N-terminal domain K15783 - 3.5.4.44 0.000000143 62.0
HKD1_k127_4026001_0 Belongs to the 'phage' integrase family - - - 0.000000000007657 73.0
HKD1_k127_4029035_0 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000001755 136.0
HKD1_k127_4029035_1 efflux transmembrane transporter activity K02004 - - 0.0000002338 61.0
HKD1_k127_4029035_2 - - - - 0.0001291 46.0
HKD1_k127_4029035_3 Metallo-beta-lactamase superfamily - - - 0.0003525 44.0
HKD1_k127_4041183_0 - K19693 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002911 257.0
HKD1_k127_4041183_1 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000001391 169.0
HKD1_k127_4041183_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000002098 104.0
HKD1_k127_4041183_3 Uncharacterised protein family UPF0066 - - - 0.0000489 46.0
HKD1_k127_4041183_4 - - - - 0.00005127 46.0
HKD1_k127_4049937_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 342.0
HKD1_k127_4049937_1 zinc metalloprotease K11749 - - 0.0000000002727 63.0
HKD1_k127_4051728_1 alpha-galactosidase K07407 - 3.2.1.22 5.518e-207 665.0
HKD1_k127_4057647_0 B12 binding domain - - - 3.092e-209 660.0
HKD1_k127_4057647_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 299.0
HKD1_k127_4057647_2 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.000000000000000000000003989 110.0
HKD1_k127_4066692_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 361.0
HKD1_k127_4066692_1 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006069 259.0
HKD1_k127_4066692_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000008649 132.0
HKD1_k127_4069034_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 586.0
HKD1_k127_4069034_1 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 336.0
HKD1_k127_4069034_10 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000005509 176.0
HKD1_k127_4069034_11 Pfam:N_methyl_2 - - - 0.000000000000000000009633 98.0
HKD1_k127_4069034_12 Bacterial membrane protein YfhO - - - 0.0000000000000001152 85.0
HKD1_k127_4069034_13 Prokaryotic N-terminal methylation motif K02650 - - 0.0000001104 61.0
HKD1_k127_4069034_14 Polymerase - - - 0.00001222 58.0
HKD1_k127_4069034_15 Carbohydrate family 9 binding domain-like - - - 0.00002482 55.0
HKD1_k127_4069034_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 301.0
HKD1_k127_4069034_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
HKD1_k127_4069034_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001215 277.0
HKD1_k127_4069034_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009581 259.0
HKD1_k127_4069034_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
HKD1_k127_4069034_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001286 220.0
HKD1_k127_4069034_8 - - - - 0.000000000000000000000000000000000000000000000000000001163 201.0
HKD1_k127_4069034_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000005213 186.0
HKD1_k127_4069964_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 518.0
HKD1_k127_4069964_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001233 268.0
HKD1_k127_4075331_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 434.0
HKD1_k127_4075331_1 lysyltransferase activity K07027 - - 0.0000000000000000000000000000002812 135.0
HKD1_k127_4079278_0 - - - - 0.000000000000000000000000000000000000000000000209 177.0
HKD1_k127_4079278_1 Integrase core domain - - - 0.00000000000000000000002186 100.0
HKD1_k127_4079278_2 Mrr N-terminal domain K07448 - - 0.0000000000000000002291 92.0
HKD1_k127_4079278_4 Scavenger mRNA decapping enzyme C-term binding - - - 0.0000000004272 63.0
HKD1_k127_4079278_6 Staphylococcal nuclease homologues - - - 0.0000005342 57.0
HKD1_k127_40797_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 513.0
HKD1_k127_40797_1 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 393.0
HKD1_k127_40797_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000005137 108.0
HKD1_k127_40797_3 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.0000000000000001821 89.0
HKD1_k127_4080501_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006817 286.0
HKD1_k127_4080501_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002232 241.0
HKD1_k127_4080501_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001937 149.0
HKD1_k127_4080501_3 found to be peripherally associated with the inner membrane in Escherichia coli K03499 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - 0.00002939 48.0
HKD1_k127_4087418_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005454 265.0
HKD1_k127_4087418_1 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.00000000000000000000000000000000000000000000000000000003347 201.0
HKD1_k127_4087418_2 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000006742 136.0
HKD1_k127_4087418_3 PFAM response regulator receiver - - - 0.00000000000000000000000000008287 119.0
HKD1_k127_4087418_4 PFAM response regulator receiver - - - 0.0000000000000000000000000122 115.0
HKD1_k127_4092881_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 503.0
HKD1_k127_4092881_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 448.0
HKD1_k127_4092881_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 287.0
HKD1_k127_4092881_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000002166 205.0
HKD1_k127_4092881_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000001475 179.0
HKD1_k127_4092881_5 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000002721 164.0
HKD1_k127_4092881_6 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000008556 146.0
HKD1_k127_4092881_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000004537 137.0
HKD1_k127_4092881_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000007452 75.0
HKD1_k127_4119229_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 571.0
HKD1_k127_4119229_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 548.0
HKD1_k127_4119229_2 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 536.0
HKD1_k127_4119229_3 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 397.0
HKD1_k127_4119229_4 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 397.0
HKD1_k127_4119229_5 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 332.0
HKD1_k127_4119229_6 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 299.0
HKD1_k127_4119229_7 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000004983 166.0
HKD1_k127_4119229_8 - - - - 0.00000000000000000000005335 106.0
HKD1_k127_4129530_0 - - - - 0.000000000000000000002247 109.0
HKD1_k127_4130543_0 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001231 289.0
HKD1_k127_4130543_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007288 254.0
HKD1_k127_4130543_2 Glucose uptake K05340 - - 0.00000000000000000000000000000000000000000000000000000000000000001272 236.0
HKD1_k127_4130543_3 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000385 229.0
HKD1_k127_4130543_4 hydrolase activity, hydrolyzing O-glycosyl compounds K00690,K01187,K01206,K01215,K01226,K17624 - 2.4.1.7,3.2.1.20,3.2.1.51,3.2.1.70,3.2.1.93,3.2.1.97 0.0000000003238 74.0
HKD1_k127_4135218_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 520.0
HKD1_k127_4135218_1 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 427.0
HKD1_k127_4135218_2 - - - - 0.000000000000000000000000000000000000001138 162.0
HKD1_k127_413818_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1193.0
HKD1_k127_413818_1 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 473.0
HKD1_k127_413818_10 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000002675 195.0
HKD1_k127_413818_11 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000001524 153.0
HKD1_k127_413818_12 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000001593 143.0
HKD1_k127_413818_13 Tetratricopeptide repeat - - - 0.00000000000000000000002133 114.0
HKD1_k127_413818_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 334.0
HKD1_k127_413818_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 326.0
HKD1_k127_413818_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003857 271.0
HKD1_k127_413818_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001145 252.0
HKD1_k127_413818_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002716 254.0
HKD1_k127_413818_7 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000001413 250.0
HKD1_k127_413818_8 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000006379 218.0
HKD1_k127_413818_9 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000003653 207.0
HKD1_k127_4140062_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 559.0
HKD1_k127_4140062_1 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000001257 181.0
HKD1_k127_4142523_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 496.0
HKD1_k127_4142523_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 445.0
HKD1_k127_4142523_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 359.0
HKD1_k127_4142523_3 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.00000000000000000000000000000000000001424 166.0
HKD1_k127_4142523_4 ABC transporter K02003 - - 0.0000000000000000000000000002584 116.0
HKD1_k127_4145687_0 dipeptidyl-peptidase activity K06978 - - 1.051e-243 767.0
HKD1_k127_4145687_1 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000001248 209.0
HKD1_k127_4161692_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 8.581e-221 703.0
HKD1_k127_4161692_1 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 378.0
HKD1_k127_4161692_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 337.0
HKD1_k127_4161692_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002273 249.0
HKD1_k127_4161692_4 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000002809 221.0
HKD1_k127_4161692_5 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000007687 207.0
HKD1_k127_4161692_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000001049 118.0
HKD1_k127_4163321_0 glucuronate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 511.0
HKD1_k127_4163321_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 502.0
HKD1_k127_4169547_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 461.0
HKD1_k127_4169547_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 440.0
HKD1_k127_4169547_10 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000006612 153.0
HKD1_k127_4169547_11 TonB C terminal K03832 - - 0.000000000000000000000000000000006312 138.0
HKD1_k127_4169547_12 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000005508 89.0
HKD1_k127_4169547_2 WD40-like Beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 381.0
HKD1_k127_4169547_3 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 294.0
HKD1_k127_4169547_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005509 246.0
HKD1_k127_4169547_5 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000005958 230.0
HKD1_k127_4169547_6 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000001739 221.0
HKD1_k127_4169547_7 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000007223 204.0
HKD1_k127_4169547_8 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000001293 183.0
HKD1_k127_4169547_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000005425 173.0
HKD1_k127_4184228_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008349 278.0
HKD1_k127_4184228_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001587 230.0
HKD1_k127_4184228_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000001377 86.0
HKD1_k127_4184228_11 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000008804 64.0
HKD1_k127_4184228_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002664 201.0
HKD1_k127_4184228_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000005351 199.0
HKD1_k127_4184228_4 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000003175 179.0
HKD1_k127_4184228_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000003633 176.0
HKD1_k127_4184228_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000004092 158.0
HKD1_k127_4184228_7 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000004162 141.0
HKD1_k127_4184228_8 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000007918 104.0
HKD1_k127_4184228_9 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000002765 97.0
HKD1_k127_4190690_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001296 272.0
HKD1_k127_4190690_1 - - - - 0.0000000000000000000008286 107.0
HKD1_k127_4190690_2 Protein of unknown function (DUF3426) - - - 0.000000007829 64.0
HKD1_k127_4190690_3 - - - - 0.000001773 55.0
HKD1_k127_4190690_4 - - - - 0.00002536 53.0
HKD1_k127_4198063_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.701e-312 968.0
HKD1_k127_4198063_1 Cysteine-rich domain K21834 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 525.0
HKD1_k127_4198063_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 379.0
HKD1_k127_4198063_3 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
HKD1_k127_4198063_4 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000003117 109.0
HKD1_k127_4201967_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 576.0
HKD1_k127_4201967_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003514 273.0
HKD1_k127_4201967_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
HKD1_k127_4201967_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001602 246.0
HKD1_k127_4203823_0 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 563.0
HKD1_k127_4203823_1 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000284 114.0
HKD1_k127_4203823_2 ndvb protein K18786 GO:0000272,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0030243,GO:0030245,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0051273,GO:0051275,GO:0071704,GO:1901575 2.4.1.321 0.0000008323 62.0
HKD1_k127_4211433_0 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 391.0
HKD1_k127_4211433_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000001753 70.0
HKD1_k127_4211560_1 - - - - 0.0000000000000000000000000000000000000000000000000003511 187.0
HKD1_k127_4211560_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000004454 157.0
HKD1_k127_4211560_3 - - - - 0.000000000000000000000005519 109.0
HKD1_k127_4224699_0 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 502.0
HKD1_k127_4224699_1 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000002007 80.0
HKD1_k127_4228762_0 Lipase maturation factor - - - 7.22e-215 680.0
HKD1_k127_4228762_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000002433 211.0
HKD1_k127_4228762_2 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000001201 166.0
HKD1_k127_4228762_3 PFAM Short-chain dehydrogenase reductase SDR K00059,K00076 - 1.1.1.100,1.1.1.159 0.000000000000000000000000001658 113.0
HKD1_k127_4232071_0 ATPases associated with a variety of cellular activities K02028,K02029,K09972,K10004 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 360.0
HKD1_k127_4232071_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001726 279.0
HKD1_k127_4232071_2 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003073 286.0
HKD1_k127_4232071_3 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000001905 74.0
HKD1_k127_4234089_0 Cytochrome c - - - 3.581e-216 704.0
HKD1_k127_4234089_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 528.0
HKD1_k127_4234089_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000904 160.0
HKD1_k127_4236037_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 2.834e-240 751.0
HKD1_k127_4236037_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 561.0
HKD1_k127_4236037_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 462.0
HKD1_k127_4236037_3 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000009825 138.0
HKD1_k127_4236659_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 8.304e-258 809.0
HKD1_k127_4236659_1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000007078 141.0
HKD1_k127_4236659_2 CBS domain - - - 0.00000000000000000000000002486 113.0
HKD1_k127_4236659_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000004199 61.0
HKD1_k127_4236659_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0001172 44.0
HKD1_k127_4244224_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001776 290.0
HKD1_k127_4244224_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000003597 206.0
HKD1_k127_4244224_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000004649 83.0
HKD1_k127_4245548_0 Pfam Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 405.0
HKD1_k127_4245548_1 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000006199 214.0
HKD1_k127_4245548_2 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.0000000000000000000000000000000000000000000000000000003984 206.0
HKD1_k127_424917_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 472.0
HKD1_k127_424917_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 421.0
HKD1_k127_424917_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 400.0
HKD1_k127_424917_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006325 268.0
HKD1_k127_424917_4 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.000000000000000000000003336 108.0
HKD1_k127_424917_5 TPR repeat-containing protein - - - 0.00000005527 57.0
HKD1_k127_4251881_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000002346 260.0
HKD1_k127_4262101_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 507.0
HKD1_k127_4262101_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 351.0
HKD1_k127_4262101_2 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000009464 161.0
HKD1_k127_4262101_4 Four helix bundle sensory module for signal transduction - - - 0.0000000001518 70.0
HKD1_k127_4286181_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 428.0
HKD1_k127_4286181_1 pfkB family carbohydrate kinase K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000003019 198.0
HKD1_k127_4286181_2 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.00000000000000000000000000000000000006391 145.0
HKD1_k127_4286181_3 ArgK protein K07588 - - 0.00000000000000000002966 94.0
HKD1_k127_4286397_0 Protein involved in outer membrane biogenesis K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 392.0
HKD1_k127_4286397_1 PFAM Alcohol dehydrogenase GroES domain protein K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 302.0
HKD1_k127_4298921_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
HKD1_k127_4298921_1 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000001608 230.0
HKD1_k127_4298921_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000001518 159.0
HKD1_k127_4298921_3 GAF domain K02482 - 2.7.13.3 0.00000000000000000000001303 102.0
HKD1_k127_4301221_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 310.0
HKD1_k127_4301221_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 283.0
HKD1_k127_4301221_2 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001416 225.0
HKD1_k127_4301221_3 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000001438 155.0
HKD1_k127_4301221_4 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000003252 154.0
HKD1_k127_4301221_5 sequence-specific DNA binding - - - 0.00000000000000000000000001645 111.0
HKD1_k127_4308379_0 Cytochrome b(C-terminal)/b6/petD K00412 - - 6.688e-233 732.0
HKD1_k127_4308379_1 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 356.0
HKD1_k127_4308379_2 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001921 306.0
HKD1_k127_4308379_3 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000000000000000000000000000000000003252 200.0
HKD1_k127_4308379_4 Rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 0.0000000000000000000000000000000001446 134.0
HKD1_k127_4308379_5 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000001443 85.0
HKD1_k127_4308379_6 glycosyl transferase family 2 K20444 - - 0.00000000004946 75.0
HKD1_k127_4308379_7 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0001322 55.0
HKD1_k127_4313673_0 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 353.0
HKD1_k127_4313673_1 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003202 271.0
HKD1_k127_4319820_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 553.0
HKD1_k127_4319820_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 457.0
HKD1_k127_4319820_2 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 430.0
HKD1_k127_4319820_3 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 359.0
HKD1_k127_4319820_4 D-lyxose isomerase K09988 - 5.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000118 266.0
HKD1_k127_4319820_5 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000004997 201.0
HKD1_k127_4319820_6 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.0000000000000000000000000000000003563 140.0
HKD1_k127_4320332_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 474.0
HKD1_k127_4320332_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000004613 247.0
HKD1_k127_4320332_3 acetyltransferase K03827 - - 0.000000000000000000000000000000000000000000000001257 179.0
HKD1_k127_4320332_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000008368 164.0
HKD1_k127_4320332_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000001192 133.0
HKD1_k127_4320332_7 - - - - 0.00005684 46.0
HKD1_k127_4323155_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 2.748e-246 769.0
HKD1_k127_4323155_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 1.618e-241 766.0
HKD1_k127_4323155_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 505.0
HKD1_k127_4323155_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001755 235.0
HKD1_k127_4323155_4 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000004086 57.0
HKD1_k127_4326525_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 490.0
HKD1_k127_4326525_1 Glucose-1-phosphate adenylyltransferase K00975 - 2.7.7.27 0.00000000006204 63.0
HKD1_k127_4327201_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000002343 205.0
HKD1_k127_4327201_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000002883 194.0
HKD1_k127_4327201_2 COGs COG3093 Plasmid maintenance system antidote protein K21498 - - 0.0000000000000000000000000000000000000007431 149.0
HKD1_k127_4327201_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000009243 106.0
HKD1_k127_4327201_4 Amidohydrolase - - - 0.000000000001321 81.0
HKD1_k127_4327201_5 Belongs to the 'phage' integrase family - - - 0.000000003809 62.0
HKD1_k127_4335567_0 Belongs to the DegT DnrJ EryC1 family K02805,K07806 - 2.6.1.59,2.6.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 570.0
HKD1_k127_4335567_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 388.0
HKD1_k127_4335567_2 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K08678,K08679 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 372.0
HKD1_k127_4335567_3 ATP-grasp domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 355.0
HKD1_k127_4335567_4 Cephalosporin hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 308.0
HKD1_k127_4335567_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008098 268.0
HKD1_k127_4335567_6 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005613 235.0
HKD1_k127_4348538_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 4.745e-262 828.0
HKD1_k127_4348538_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 600.0
HKD1_k127_4348538_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000009432 144.0
HKD1_k127_4348538_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000003496 103.0
HKD1_k127_4348538_12 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000223 60.0
HKD1_k127_4348538_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 567.0
HKD1_k127_4348538_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 546.0
HKD1_k127_4348538_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 485.0
HKD1_k127_4348538_5 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 392.0
HKD1_k127_4348538_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 338.0
HKD1_k127_4348538_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000008475 262.0
HKD1_k127_4348538_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002943 238.0
HKD1_k127_4348538_9 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000002146 222.0
HKD1_k127_4363193_0 peptidyl-tyrosine sulfation - - - 9.816e-227 723.0
HKD1_k127_4363193_1 peptidyl-tyrosine sulfation - - - 2.396e-205 654.0
HKD1_k127_4363193_2 mannose metabolic process K01191,K03217 - 3.2.1.24 0.000000000000000000000000000000691 142.0
HKD1_k127_4363193_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000004768 107.0
HKD1_k127_4376973_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 550.0
HKD1_k127_4376973_1 mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 254.0
HKD1_k127_4376973_2 DDE superfamily endonuclease - - - 0.00000000000000000000000000000001313 128.0
HKD1_k127_4376973_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000004963 123.0
HKD1_k127_4376973_4 - - - - 0.000001297 52.0
HKD1_k127_4387069_0 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 341.0
HKD1_k127_4387069_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 331.0
HKD1_k127_4387069_2 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000006871 263.0
HKD1_k127_4387069_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000001921 213.0
HKD1_k127_4387069_4 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000003608 203.0
HKD1_k127_4387069_5 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000009307 201.0
HKD1_k127_4387069_6 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000007899 172.0
HKD1_k127_4387069_7 Protein of unknown function (DUF465) - - - 0.0000000007718 63.0
HKD1_k127_4390701_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000005713 182.0
HKD1_k127_4390701_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000005564 116.0
HKD1_k127_4398077_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 453.0
HKD1_k127_4398077_1 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002428 266.0
HKD1_k127_4398077_2 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 253.0
HKD1_k127_4398077_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000001705 205.0
HKD1_k127_4400181_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.794e-202 639.0
HKD1_k127_4400181_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 403.0
HKD1_k127_4400181_2 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 360.0
HKD1_k127_4400181_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000004485 220.0
HKD1_k127_4400181_4 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000175 164.0
HKD1_k127_4400181_5 Glycosyl hydrolases family 38 N-terminal domain - - - 0.0000000000000000000000000000000000003485 144.0
HKD1_k127_4400181_6 Sigma-54 interaction domain - - - 0.000000000000000000000000129 112.0
HKD1_k127_4400181_7 YsiA-like protein, C-terminal region K09017 - - 0.0000000000000000002269 95.0
HKD1_k127_4400181_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0003162 49.0
HKD1_k127_4407092_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
HKD1_k127_4425114_0 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 344.0
HKD1_k127_4425114_1 Phosphoenolpyruvate hydrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005862 255.0
HKD1_k127_4425114_2 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000179 243.0
HKD1_k127_4425114_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000005092 116.0
HKD1_k127_4425114_4 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000001765 109.0
HKD1_k127_4425114_6 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000002853 55.0
HKD1_k127_442662_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 532.0
HKD1_k127_442662_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 517.0
HKD1_k127_442662_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 409.0
HKD1_k127_442662_3 Malate/L-lactate dehydrogenase K00073,K13574 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000009622 264.0
HKD1_k127_4442423_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000004651 197.0
HKD1_k127_4442423_1 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000002564 161.0
HKD1_k127_4450065_0 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 304.0
HKD1_k127_4450065_1 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.000000000000000000000000000000008353 136.0
HKD1_k127_4450065_2 Sulfatase K01130 - 3.1.6.1 0.000000005892 62.0
HKD1_k127_4450065_3 Uncharacterised ArCR, COG2043 - - - 0.0000398 49.0
HKD1_k127_4455238_0 Belongs to the TPP enzyme family K01568,K04103 - 4.1.1.1,4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 436.0
HKD1_k127_4455238_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 400.0
HKD1_k127_4455238_2 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 381.0
HKD1_k127_4455238_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.000000000000000000000007006 103.0
HKD1_k127_4458941_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000002266 224.0
HKD1_k127_4458941_2 - - - - 0.000000000000111 74.0
HKD1_k127_4470934_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 7.336e-230 719.0
HKD1_k127_4470934_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 593.0
HKD1_k127_4470934_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000495 142.0
HKD1_k127_4470934_11 Thioredoxin-like - - - 0.0000000000000000000000000000001047 130.0
HKD1_k127_4470934_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000001188 129.0
HKD1_k127_4470934_13 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000003311 122.0
HKD1_k127_4470934_14 - - - - 0.0000000001879 67.0
HKD1_k127_4470934_2 PFAM Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 495.0
HKD1_k127_4470934_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 351.0
HKD1_k127_4470934_4 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 330.0
HKD1_k127_4470934_5 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000006778 264.0
HKD1_k127_4470934_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000002669 223.0
HKD1_k127_4470934_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
HKD1_k127_4470934_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000009754 185.0
HKD1_k127_4470934_9 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000008814 149.0
HKD1_k127_4474666_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 469.0
HKD1_k127_4474666_1 PFAM Molybdopterin oxidoreductase - - - 0.0000000001049 64.0
HKD1_k127_4476191_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 9.334e-276 860.0
HKD1_k127_4478005_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.283e-287 889.0
HKD1_k127_4478005_1 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 604.0
HKD1_k127_4478005_10 Tetratricopeptide repeat - - - 0.0000000000000000000001484 106.0
HKD1_k127_4478005_11 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000000001753 99.0
HKD1_k127_4478005_12 cell redox homeostasis K02199 - - 0.00000000000000000001998 102.0
HKD1_k127_4478005_13 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000001105 51.0
HKD1_k127_4478005_14 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.0005285 46.0
HKD1_k127_4478005_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 408.0
HKD1_k127_4478005_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 399.0
HKD1_k127_4478005_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 379.0
HKD1_k127_4478005_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 351.0
HKD1_k127_4478005_6 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002475 277.0
HKD1_k127_4478005_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002232 267.0
HKD1_k127_4478005_8 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003496 255.0
HKD1_k127_4478005_9 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.0000000000000000000000000000000000000000001249 168.0
HKD1_k127_4483230_0 - - - - 0.00000000000000000000000000000001018 134.0
HKD1_k127_4483230_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000007337 87.0
HKD1_k127_4483230_4 cell redox homeostasis K00520 - 1.16.1.1 0.00005108 51.0
HKD1_k127_4499714_0 Protein of unknown function (DUF1501) - - - 2.092e-216 681.0
HKD1_k127_4499714_1 Belongs to the purine-cytosine permease (2.A.39) family K10974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
HKD1_k127_4499714_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000009629 233.0
HKD1_k127_4528764_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 609.0
HKD1_k127_4528764_1 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000009588 201.0
HKD1_k127_4528764_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000004394 199.0
HKD1_k127_4528764_3 Protein of unknown function (DUF3108) - - - 0.00000000088 67.0
HKD1_k127_4530837_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 476.0
HKD1_k127_4530837_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 437.0
HKD1_k127_4530837_2 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000008919 172.0
HKD1_k127_4530837_3 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000004359 94.0
HKD1_k127_4530837_4 chorismate lyase activity - - - 0.00001506 49.0
HKD1_k127_4535490_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 3.561e-205 651.0
HKD1_k127_4535490_1 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 287.0
HKD1_k127_4535490_2 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000000000000000001035 181.0
HKD1_k127_4535490_3 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.00000002157 56.0
HKD1_k127_4542859_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.058e-286 896.0
HKD1_k127_4542859_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000004206 190.0
HKD1_k127_4542859_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000001993 165.0
HKD1_k127_4542859_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000001892 65.0
HKD1_k127_4548359_0 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 400.0
HKD1_k127_4548359_1 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 317.0
HKD1_k127_4548359_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002271 282.0
HKD1_k127_4548359_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000008949 197.0
HKD1_k127_4548359_4 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000003351 94.0
HKD1_k127_4550993_0 Rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 4.594e-266 832.0
HKD1_k127_4550993_1 Glycogen debranching enzyme K05989 - 3.2.1.40 2.044e-263 840.0
HKD1_k127_4550993_2 PFAM Xylose isomerase K01820 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 593.0
HKD1_k127_4550993_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 502.0
HKD1_k127_4550993_4 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 318.0
HKD1_k127_4550993_5 Periplasmic binding protein domain K10559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003246 287.0
HKD1_k127_4550993_6 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004445 283.0
HKD1_k127_4550993_7 Monosaccharide ABC transporter membrane protein, CUT2 family K10557,K10561 - - 0.0000000000000000000000000000000000000000000000000000002909 210.0
HKD1_k127_4550993_8 NAD binding K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000007054 167.0
HKD1_k127_4553541_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 388.0
HKD1_k127_4553541_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 297.0
HKD1_k127_4553541_2 - - - - 0.0000002405 55.0
HKD1_k127_4554449_0 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006443 285.0
HKD1_k127_4554449_1 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000235 160.0
HKD1_k127_4554449_2 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000000000229 127.0
HKD1_k127_4554449_3 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000001163 89.0
HKD1_k127_4554449_4 ECF-type riboflavin transporter, S component K16924 - - 0.00000000000000002285 82.0
HKD1_k127_4554449_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000846 68.0
HKD1_k127_458326_0 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000005923 208.0
HKD1_k127_458326_1 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000000005345 187.0
HKD1_k127_458326_2 Alginate export - - - 0.00000000000000001624 87.0
HKD1_k127_4618727_0 Fic/DOC family K04095 - - 0.000000000000000000000000000000000000000000000000000000001283 206.0
HKD1_k127_4618727_1 - - - - 0.000000000000000000000000000000000000000002487 163.0
HKD1_k127_4618727_2 - - - - 0.0000003779 53.0
HKD1_k127_4618727_3 - - - - 0.0002445 46.0
HKD1_k127_4619235_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.405e-260 809.0
HKD1_k127_4619235_1 membrane carboxypeptidase (Penicillin-binding protein) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 471.0
HKD1_k127_4619235_2 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000002356 154.0
HKD1_k127_4619235_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000001149 144.0
HKD1_k127_4619395_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 598.0
HKD1_k127_4628607_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 505.0
HKD1_k127_4628607_1 PFAM Glycosyl transferase, group 1 K03208 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 456.0
HKD1_k127_4628607_2 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 417.0
HKD1_k127_4628607_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 411.0
HKD1_k127_4628607_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 407.0
HKD1_k127_4628607_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 321.0
HKD1_k127_4628607_6 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000001523 204.0
HKD1_k127_4628607_7 cellulose binding - - - 0.0000000000000000000000000000000000001342 157.0
HKD1_k127_4628607_8 - - - - 0.0000001055 62.0
HKD1_k127_4631429_0 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 506.0
HKD1_k127_4631429_1 L-fucose isomerase K01818 - 5.3.1.25,5.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 481.0
HKD1_k127_4631429_2 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 477.0
HKD1_k127_4631429_3 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 414.0
HKD1_k127_4631429_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 406.0
HKD1_k127_4631429_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000005413 194.0
HKD1_k127_4631429_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000005211 80.0
HKD1_k127_4637157_0 - K19693 - - 0.0000000000000000000000000000000000000000000000000000000000001589 237.0
HKD1_k127_4647384_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 499.0
HKD1_k127_4647384_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 475.0
HKD1_k127_4647384_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 374.0
HKD1_k127_4647384_3 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 372.0
HKD1_k127_4647384_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000542 215.0
HKD1_k127_4647384_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002603 109.0
HKD1_k127_4647384_6 - - - - 0.00005115 53.0
HKD1_k127_4650978_0 PFAM Amidase - - - 1.393e-255 803.0
HKD1_k127_4650978_1 Domain of unknown function (DUF5060) - - - 2.163e-215 682.0
HKD1_k127_4650978_10 - - - - 0.0001721 50.0
HKD1_k127_4650978_2 - - - - 0.0000000000000000000000000000000000000000000003827 172.0
HKD1_k127_4650978_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000009204 166.0
HKD1_k127_4650978_4 Domain of unknown function (DUF4252) - - - 0.0000000000000000000000000000000000009765 145.0
HKD1_k127_4650978_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000005576 144.0
HKD1_k127_4650978_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000006665 142.0
HKD1_k127_4650978_7 Acetyltransferase (GNAT) family - - - 0.000000000000000000000004222 106.0
HKD1_k127_4650978_8 WD40 repeats - - - 0.00000000000000002545 90.0
HKD1_k127_4650978_9 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000003809 69.0
HKD1_k127_4663903_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 323.0
HKD1_k127_4663903_1 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000005203 174.0
HKD1_k127_4663903_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000006293 126.0
HKD1_k127_4663903_3 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000001169 124.0
HKD1_k127_4663903_4 - - - - 0.00000000000000000003498 102.0
HKD1_k127_4663903_5 ThiS family K03154 - - 0.000000000000001267 79.0
HKD1_k127_4669953_0 dipeptidyl-peptidase activity K06978 - - 2.089e-235 742.0
HKD1_k127_4669953_1 dipeptidyl-peptidase activity K06978 - - 1.562e-232 732.0
HKD1_k127_4669953_2 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000002111 208.0
HKD1_k127_4677551_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1008.0
HKD1_k127_4677551_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 447.0
HKD1_k127_4677551_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000004514 101.0
HKD1_k127_4677551_3 universal stress protein - - - 0.00000000003594 75.0
HKD1_k127_4677896_0 PQQ enzyme repeat K00117 - 1.1.5.2 2.049e-236 749.0
HKD1_k127_4677896_1 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000004421 240.0
HKD1_k127_4677896_2 mannose metabolic process K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000157 180.0
HKD1_k127_4677896_3 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000000000005375 150.0
HKD1_k127_4691721_0 FAD linked oxidase domain protein - - - 9.861e-242 753.0
HKD1_k127_4691721_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001382 258.0
HKD1_k127_4699615_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1231.0
HKD1_k127_4699615_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 563.0
HKD1_k127_4719100_0 Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 419.0
HKD1_k127_4719100_1 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000001549 284.0
HKD1_k127_4719100_2 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000003391 67.0
HKD1_k127_4738282_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 386.0
HKD1_k127_4738282_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000005576 144.0
HKD1_k127_4751619_0 - - - - 0.000004502 56.0
HKD1_k127_4757587_0 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 338.0
HKD1_k127_4757587_1 Major Facilitator Superfamily K08193 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009605,GO:0009607,GO:0009624,GO:0009628,GO:0015291,GO:0015318,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055035,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000002899 233.0
HKD1_k127_4757587_2 cellulase activity - - - 0.000000000000000000000000000000000005085 143.0
HKD1_k127_4757587_3 Transposase is116 is110 is902 family K07486 - - 0.00008226 45.0
HKD1_k127_4767426_0 positive regulation of growth rate - - - 0.0000005986 58.0
HKD1_k127_4767426_1 WD40 repeats - - - 0.000009169 55.0
HKD1_k127_4767426_2 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.0001025 54.0
HKD1_k127_4780363_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 344.0
HKD1_k127_4780363_1 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 314.0
HKD1_k127_4780363_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000002288 174.0
HKD1_k127_4780363_3 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000007064 184.0
HKD1_k127_4780363_4 VanZ like family - - - 0.000000000000000000000000000001705 126.0
HKD1_k127_4780363_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000001199 93.0
HKD1_k127_4789098_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.134e-277 868.0
HKD1_k127_4789098_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 416.0
HKD1_k127_4789098_2 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 376.0
HKD1_k127_4789098_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 364.0
HKD1_k127_4789098_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 333.0
HKD1_k127_4789098_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 315.0
HKD1_k127_4789098_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001031 180.0
HKD1_k127_479656_0 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 606.0
HKD1_k127_479656_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 512.0
HKD1_k127_479656_2 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 477.0
HKD1_k127_479656_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 312.0
HKD1_k127_479656_4 fumarate hydratase activity - - - 0.0000000000000000000000000000003367 129.0
HKD1_k127_4803653_0 secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 558.0
HKD1_k127_4803653_1 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 393.0
HKD1_k127_4803653_2 Type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000004976 245.0
HKD1_k127_4803653_3 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000618 245.0
HKD1_k127_4803653_4 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000001771 216.0
HKD1_k127_4803653_5 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000000000000000000000005413 194.0
HKD1_k127_4803653_6 Type IV leader peptidase family - - - 0.00000000000000000000000005149 114.0
HKD1_k127_4803653_7 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000001262 110.0
HKD1_k127_4803653_8 repeat-containing protein - - - 0.000000000000003315 88.0
HKD1_k127_4814078_0 Belongs to the ATP-dependent AMP-binding enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 627.0
HKD1_k127_4814078_1 Amino acid adenylation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 501.0
HKD1_k127_4820631_0 ribulose-bisphosphate carboxylase activity K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 510.0
HKD1_k127_4820631_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 478.0
HKD1_k127_4820631_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003321 262.0
HKD1_k127_4820631_3 carboxylic ester hydrolase activity - - - 0.0000000000000000000022 96.0
HKD1_k127_4827194_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 3.022e-195 625.0
HKD1_k127_4827194_1 - - - - 0.000002675 49.0
HKD1_k127_4828416_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.55e-254 795.0
HKD1_k127_4828416_1 Multicopper oxidase K06324 - 1.16.3.3 9.5e-202 653.0
HKD1_k127_4828416_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 317.0
HKD1_k127_4828416_3 NosL - - - 0.000000000000000000000000000000000000000000000000000000000463 207.0
HKD1_k127_4828416_4 NosL - - - 0.0000000000000000000000000000000000000000000001129 173.0
HKD1_k127_4828416_5 YtkA-like - - - 0.00000000005086 69.0
HKD1_k127_4833986_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000008734 225.0
HKD1_k127_4833986_2 Protein of unknown function DUF72 - - - 0.00000000000001394 76.0
HKD1_k127_4833986_3 Protein of unknown function DUF72 - - - 0.0000001155 56.0
HKD1_k127_4854876_0 PFAM response regulator receiver K11384 - - 3.086e-219 687.0
HKD1_k127_4854876_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 313.0
HKD1_k127_4858509_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 379.0
HKD1_k127_4858509_1 - - - - 0.00002366 51.0
HKD1_k127_487072_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.657e-236 752.0
HKD1_k127_487072_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 473.0
HKD1_k127_487072_2 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 349.0
HKD1_k127_487072_3 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000005369 212.0
HKD1_k127_487072_5 FR47-like protein K03829 - - 0.0007745 42.0
HKD1_k127_4886210_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 497.0
HKD1_k127_4886210_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 441.0
HKD1_k127_4886210_10 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000008824 145.0
HKD1_k127_4886210_11 Preprotein translocase, YajC K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000001225 83.0
HKD1_k127_4886210_12 Protein of unknown function (DUF3108) - - - 0.0000000000003898 74.0
HKD1_k127_4886210_13 - - - - 0.000007653 50.0
HKD1_k127_4886210_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 443.0
HKD1_k127_4886210_3 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 418.0
HKD1_k127_4886210_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 376.0
HKD1_k127_4886210_5 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 347.0
HKD1_k127_4886210_6 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 304.0
HKD1_k127_4886210_7 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000004076 222.0
HKD1_k127_4886210_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000291 198.0
HKD1_k127_4886210_9 Alpha beta hydrolase fold-3 domain protein - - - 0.000000000000000000000000000000000217 139.0
HKD1_k127_4886435_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 467.0
HKD1_k127_4886435_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 414.0
HKD1_k127_4886435_2 domain, Protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000431 273.0
HKD1_k127_4918929_0 Demethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000000000000000000000005036 192.0
HKD1_k127_4918929_1 Bacterial membrane protein, YfhO - - - 0.000000001614 70.0
HKD1_k127_4927090_0 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008533 253.0
HKD1_k127_4927090_1 PFAM TonB-dependent Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006687 253.0
HKD1_k127_4927090_2 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000001835 198.0
HKD1_k127_4944548_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00001105 57.0
HKD1_k127_4944548_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00005191 55.0
HKD1_k127_4951336_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 534.0
HKD1_k127_4951336_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 512.0
HKD1_k127_4951336_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 411.0
HKD1_k127_4951336_3 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 317.0
HKD1_k127_4951336_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007839 266.0
HKD1_k127_4951336_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000008619 243.0
HKD1_k127_4951336_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000001552 173.0
HKD1_k127_4951336_7 Protein of unknown function, DUF393 - - - 0.00001732 52.0
HKD1_k127_4951423_0 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 564.0
HKD1_k127_4951423_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001605 276.0
HKD1_k127_4951423_2 Transposase - - - 0.000000000000000000000000000000000000000007041 171.0
HKD1_k127_4951423_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000003687 144.0
HKD1_k127_4951540_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 555.0
HKD1_k127_4951540_1 Hydrolase Family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 516.0
HKD1_k127_4951540_2 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000001943 178.0
HKD1_k127_4951540_3 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000002566 145.0
HKD1_k127_4951540_4 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000001124 107.0
HKD1_k127_4951540_5 Hemerythrin HHE cation binding domain - - - 0.000001164 53.0
HKD1_k127_4970632_0 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 327.0
HKD1_k127_4970632_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000001211 217.0
HKD1_k127_4970632_2 - - - - 0.0000006023 54.0
HKD1_k127_4998042_0 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145,K05829 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 488.0
HKD1_k127_4998042_1 Belongs to the RimK family K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 401.0
HKD1_k127_4998042_2 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008201 266.0
HKD1_k127_4998042_3 - K05826 - - 0.0000000000000000004801 87.0
HKD1_k127_4998042_4 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000004255 71.0
HKD1_k127_50014_0 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 308.0
HKD1_k127_50014_1 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001152 279.0
HKD1_k127_5005298_0 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 359.0
HKD1_k127_5005298_1 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000006955 214.0
HKD1_k127_5005298_2 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.0000000000000000000000000007478 124.0
HKD1_k127_5005298_3 Helix-turn-helix domain K15539 - - 0.00000000000000000000003893 111.0
HKD1_k127_5005298_4 - - - - 0.00000000000000000001205 95.0
HKD1_k127_5005298_5 - - - - 0.000000000584 70.0
HKD1_k127_500756_0 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 478.0
HKD1_k127_500756_1 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 466.0
HKD1_k127_500756_2 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 355.0
HKD1_k127_500756_3 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000003406 241.0
HKD1_k127_500756_4 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000001382 193.0
HKD1_k127_5031492_0 RNA binding K06959 - - 2.18e-244 786.0
HKD1_k127_5031492_1 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 600.0
HKD1_k127_5031492_10 - - - - 0.00000000000000000000000001809 117.0
HKD1_k127_5031492_11 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000007332 81.0
HKD1_k127_5031492_12 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.00000000000001116 76.0
HKD1_k127_5031492_13 Cupin 2, conserved barrel domain protein - - - 0.0000000000006846 74.0
HKD1_k127_5031492_14 TIGRFAM membrane-bound dehydrogenase domain protein - - - 0.000000002145 68.0
HKD1_k127_5031492_15 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000003816 64.0
HKD1_k127_5031492_2 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 488.0
HKD1_k127_5031492_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 471.0
HKD1_k127_5031492_4 Cysteine synthase B K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 407.0
HKD1_k127_5031492_5 with different specificities (related to short-chain alcohol K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 337.0
HKD1_k127_5031492_6 Peptidase, M16 K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 299.0
HKD1_k127_5031492_7 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002261 284.0
HKD1_k127_5031492_8 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
HKD1_k127_5031492_9 - - - - 0.0000000000000000000000000000004369 138.0
HKD1_k127_5034160_1 mannose metabolic process K01191,K03217 - 3.2.1.24 0.0000000000000000000003308 111.0
HKD1_k127_5034160_2 - - - - 0.000000000000000002416 93.0
HKD1_k127_5034160_3 - - - - 0.000000000004156 70.0
HKD1_k127_5034160_4 - - - - 0.000000003279 61.0
HKD1_k127_5058685_0 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 553.0
HKD1_k127_5058685_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 488.0
HKD1_k127_5058685_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 444.0
HKD1_k127_5058685_3 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 392.0
HKD1_k127_5058685_4 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 319.0
HKD1_k127_5068329_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004775 246.0
HKD1_k127_5068329_1 PFAM conserved - - - 0.0000000000000000000000000000000000000000006518 165.0
HKD1_k127_5068329_2 - - - - 0.00000000000000000000000000000001352 130.0
HKD1_k127_5068329_3 Involved in the tonB-independent uptake of proteins K13669 - - 0.000000008282 57.0
HKD1_k127_5068329_4 RibD C-terminal domain K00287 - 1.5.1.3 0.0000002518 54.0
HKD1_k127_5068329_5 RibD C-terminal domain K00287 - 1.5.1.3 0.000006736 51.0
HKD1_k127_5084552_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 458.0
HKD1_k127_5084552_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000545 125.0
HKD1_k127_5084552_2 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000001105 72.0
HKD1_k127_5085804_0 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 3.8e-240 763.0
HKD1_k127_5085804_1 ABC transporter, transmembrane K18890 - - 3.459e-210 670.0
HKD1_k127_5085804_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001514 201.0
HKD1_k127_5085804_11 Protein of unknown function (DUF1553) - - - 0.000000000000000000000000000000000002929 144.0
HKD1_k127_5085804_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000008652 78.0
HKD1_k127_5085804_13 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000322 68.0
HKD1_k127_5085804_2 Protein of unknown function (DUF1553) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 607.0
HKD1_k127_5085804_3 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 603.0
HKD1_k127_5085804_4 PFAM Mandelate racemase muconate lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 415.0
HKD1_k127_5085804_5 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 370.0
HKD1_k127_5085804_6 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 320.0
HKD1_k127_5085804_7 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 321.0
HKD1_k127_5085804_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000003154 253.0
HKD1_k127_5085804_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001339 244.0
HKD1_k127_5095014_0 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 295.0
HKD1_k127_5095014_1 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000004053 89.0
HKD1_k127_5095014_2 KAP family P-loop domain - - - 0.0000000000000000001889 96.0
HKD1_k127_5095014_4 - - - - 0.00002678 52.0
HKD1_k127_5096190_0 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 332.0
HKD1_k127_5096190_1 Domains Cache_1, HAMP, PAS, PAS K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000005542 231.0
HKD1_k127_5096190_2 Domain of unknown function (DUF1820) - - - 0.0000000000000000000000000000000000001805 144.0
HKD1_k127_5096190_3 Protein of unknown function (DUF3465) - - - 0.000000000000000000000000003475 116.0
HKD1_k127_5104063_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 1.849e-226 723.0
HKD1_k127_5104063_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000002545 175.0
HKD1_k127_512398_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000001565 66.0
HKD1_k127_5133453_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 470.0
HKD1_k127_5133453_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 421.0
HKD1_k127_5133453_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000001065 219.0
HKD1_k127_5133453_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000004079 200.0
HKD1_k127_5133453_4 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0002408 52.0
HKD1_k127_5141466_0 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 508.0
HKD1_k127_5141466_1 Phosphoenolpyruvate hydrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 407.0
HKD1_k127_5141466_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 362.0
HKD1_k127_5141466_3 COG1312 D-mannonate dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001364 248.0
HKD1_k127_5141466_4 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000008001 196.0
HKD1_k127_5141466_5 hmm pf01609 - - - 0.000000001068 64.0
HKD1_k127_5156045_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 317.0
HKD1_k127_5156045_1 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 289.0
HKD1_k127_5156045_2 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000003163 192.0
HKD1_k127_5156045_3 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000000004095 169.0
HKD1_k127_5156045_4 Sugar proton symporter K02856 - - 0.0000000000000000000000000000001163 137.0
HKD1_k127_5156045_5 Polysaccharide pyruvyl transferase - - - 0.0000000002751 74.0
HKD1_k127_516241_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000005816 206.0
HKD1_k127_516241_1 Conserved protein - - - 0.0000000000000000000000000000000000000002763 158.0
HKD1_k127_516241_2 His Kinase A (phosphoacceptor) domain - - - 0.000000003844 68.0
HKD1_k127_5163087_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 526.0
HKD1_k127_5163087_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 413.0
HKD1_k127_5163087_2 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000003472 183.0
HKD1_k127_5163087_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000002064 117.0
HKD1_k127_5170818_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1262.0
HKD1_k127_5170818_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 498.0
HKD1_k127_5170818_10 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000538 218.0
HKD1_k127_5170818_11 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000001122 187.0
HKD1_k127_5170818_12 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000102 175.0
HKD1_k127_5170818_13 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000004432 162.0
HKD1_k127_5170818_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000003569 138.0
HKD1_k127_5170818_15 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000005561 118.0
HKD1_k127_5170818_16 Ribosomal protein L31 - - - 0.0000000000000000000000003048 106.0
HKD1_k127_5170818_17 transmembrane transport - - - 0.0000000000000000000008259 104.0
HKD1_k127_5170818_18 Psort location Cytoplasmic, score - - - 0.0000000000000000000008934 104.0
HKD1_k127_5170818_19 - - - - 0.000000000005829 68.0
HKD1_k127_5170818_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 412.0
HKD1_k127_5170818_20 - - - - 0.0002896 45.0
HKD1_k127_5170818_3 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 375.0
HKD1_k127_5170818_4 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 350.0
HKD1_k127_5170818_5 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 325.0
HKD1_k127_5170818_6 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 316.0
HKD1_k127_5170818_7 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 313.0
HKD1_k127_5170818_8 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 299.0
HKD1_k127_5170818_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000002041 218.0
HKD1_k127_5199846_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1158.0
HKD1_k127_5199846_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 502.0
HKD1_k127_5199846_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 467.0
HKD1_k127_5199846_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 452.0
HKD1_k127_5199846_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004405 262.0
HKD1_k127_5199846_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000006666 225.0
HKD1_k127_5199846_6 - - - - 0.00000000993 61.0
HKD1_k127_5232873_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.543e-198 633.0
HKD1_k127_5232873_1 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 452.0
HKD1_k127_5232873_2 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 355.0
HKD1_k127_5232873_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009291 287.0
HKD1_k127_5232873_4 Elongation factor P K02356 - - 0.00000000000000000000000000000000000000000000008766 175.0
HKD1_k127_5232873_5 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.00000000000000000000009564 102.0
HKD1_k127_5232873_6 YtxH-like protein - - - 0.0000000000005821 76.0
HKD1_k127_5232873_7 - - - - 0.00000004849 63.0
HKD1_k127_5232873_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0001318 53.0
HKD1_k127_5232873_9 Protein of unknown function (DUF2934) - - - 0.000285 48.0
HKD1_k127_5236441_0 PFAM Cytochrome c assembly protein K02198 - - 4.81e-214 685.0
HKD1_k127_5236441_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000008191 131.0
HKD1_k127_5236441_2 subunit of a heme lyase K02200 - - 0.00000000000000003975 89.0
HKD1_k127_5236441_3 - - - - 0.0000184 51.0
HKD1_k127_5238265_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 336.0
HKD1_k127_5238265_1 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 314.0
HKD1_k127_5238265_2 - - - - 0.000000000000000000000000000000000000000000000000007575 188.0
HKD1_k127_5240671_0 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000002023 188.0
HKD1_k127_5240671_1 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000009494 166.0
HKD1_k127_5240671_2 Alpha/beta hydrolase family - - - 0.000000000000000000001165 98.0
HKD1_k127_5248387_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 5.141e-269 843.0
HKD1_k127_5248799_0 Belongs to the GSP D family K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 462.0
HKD1_k127_5248799_1 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 358.0
HKD1_k127_5248799_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 303.0
HKD1_k127_5248799_3 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000003083 81.0
HKD1_k127_5254516_0 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000001726 169.0
HKD1_k127_5254516_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000007752 164.0
HKD1_k127_5255999_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 291.0
HKD1_k127_5255999_1 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000234 242.0
HKD1_k127_5255999_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000001823 187.0
HKD1_k127_5255999_3 nUDIX hydrolase K01515,K12945 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0046872,GO:0052751 3.6.1.13 0.000000000000000000000000000000000000448 148.0
HKD1_k127_5255999_4 Cytidine monophosphokinase K00876 - 2.7.1.48 0.00000000000000000000000003579 109.0
HKD1_k127_5258396_0 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000005904 239.0
HKD1_k127_5258396_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000002373 226.0
HKD1_k127_5258396_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000001372 163.0
HKD1_k127_5258396_3 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.000000000000000000000000000008832 123.0
HKD1_k127_5284598_0 pyruvate kinase activity K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
HKD1_k127_5284598_1 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002481 254.0
HKD1_k127_5284598_2 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000002028 156.0
HKD1_k127_529721_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 567.0
HKD1_k127_5299809_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.076e-229 730.0
HKD1_k127_5299809_1 B12 binding domain - - - 2.721e-214 676.0
HKD1_k127_5299809_10 Tetratricopeptide repeat - - - 0.0000000000002485 77.0
HKD1_k127_5299809_11 SMART Elongator protein 3 MiaB NifB - - - 0.0000001103 57.0
HKD1_k127_5299809_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 576.0
HKD1_k127_5299809_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 513.0
HKD1_k127_5299809_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 454.0
HKD1_k127_5299809_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000478 214.0
HKD1_k127_5299809_6 Histidine kinase internal region K02478 - 2.7.13.3 0.000000000000000000000000000000000000000003419 171.0
HKD1_k127_5299809_7 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000008474 161.0
HKD1_k127_5299809_8 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000003467 128.0
HKD1_k127_5299809_9 - - - - 0.000000000000000000000001247 117.0
HKD1_k127_5306945_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 417.0
HKD1_k127_5306945_1 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 320.0
HKD1_k127_5308923_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 384.0
HKD1_k127_5308923_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001287 238.0
HKD1_k127_5308923_2 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000001583 238.0
HKD1_k127_5308923_3 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000001679 224.0
HKD1_k127_5308923_4 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.00000000000000000000001465 104.0
HKD1_k127_5308923_5 Histidine kinase K10125 - 2.7.13.3 0.000000000000000000001191 98.0
HKD1_k127_5313578_0 family 2 sugar binding - - - 0.0 1102.0
HKD1_k127_5313578_1 Putative cyclase - - - 0.00000000000000000000001214 109.0
HKD1_k127_5313578_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000002149 66.0
HKD1_k127_5323761_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 509.0
HKD1_k127_5323761_1 RRNA methyltransferase AviRa K21515 - 2.1.1.209 0.000000000000000000000000000000000000000000000000002358 192.0
HKD1_k127_5323761_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000001312 102.0
HKD1_k127_5324801_0 protocatechuate 3,4-dioxygenase activity - - - 3.108e-280 897.0
HKD1_k127_5324801_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
HKD1_k127_5324801_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001326 167.0
HKD1_k127_5324801_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000001937 93.0
HKD1_k127_5324801_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000001167 71.0
HKD1_k127_5329131_0 permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 537.0
HKD1_k127_5329131_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 526.0
HKD1_k127_5329131_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 361.0
HKD1_k127_5329131_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001605 277.0
HKD1_k127_5329131_4 ABC-type molybdate transport system, ATPase component K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000002227 238.0
HKD1_k127_5329131_5 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000001314 222.0
HKD1_k127_5329131_6 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000009099 192.0
HKD1_k127_5329131_7 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.0000000000000000000000000000000000000000003564 162.0
HKD1_k127_5329131_8 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.00000000000000000002708 96.0
HKD1_k127_5329131_9 - - - - 0.00000000004299 76.0
HKD1_k127_5342531_0 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 558.0
HKD1_k127_5342531_1 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 497.0
HKD1_k127_5342531_10 Histidine kinase - - - 0.0000106 57.0
HKD1_k127_5342531_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 394.0
HKD1_k127_5342531_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000102 220.0
HKD1_k127_5342531_5 Protein conserved in bacteria - - - 0.00000000000000000000000000001457 130.0
HKD1_k127_5342531_6 - - - - 0.0000000003178 65.0
HKD1_k127_5342531_7 hydroperoxide reductase activity - - - 0.00000000109 69.0
HKD1_k127_5342531_8 Carboxymuconolactone decarboxylase family - - - 0.0000000646 63.0
HKD1_k127_5342531_9 Protein of unknown function (DUF3179) - - - 0.000001617 57.0
HKD1_k127_5343519_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1031.0
HKD1_k127_5343519_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 4.781e-238 747.0
HKD1_k127_5343519_10 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001093 83.0
HKD1_k127_5343519_11 spore germination K03605,K06012 GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 0.000000000000001732 83.0
HKD1_k127_5343519_2 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 510.0
HKD1_k127_5343519_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 467.0
HKD1_k127_5343519_4 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 311.0
HKD1_k127_5343519_5 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 304.0
HKD1_k127_5343519_6 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000004746 235.0
HKD1_k127_5343519_7 CoA binding domain - - - 0.000000000000000000000000000000000001447 145.0
HKD1_k127_5343519_8 PFAM cyclase family protein - - - 0.000000000000000000000000000000007534 136.0
HKD1_k127_5343519_9 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000007482 111.0
HKD1_k127_5346062_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 425.0
HKD1_k127_5346062_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000005577 196.0
HKD1_k127_5346062_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000001284 174.0
HKD1_k127_5346062_3 CYTH domain - - - 0.00000000000000000000000000000000000000008925 158.0
HKD1_k127_5346062_4 Tetratricopeptide repeat - - - 0.000000000000000004737 97.0
HKD1_k127_5346062_5 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000001772 84.0
HKD1_k127_5355231_0 DNA methylase K07316 - 2.1.1.72 4.118e-217 684.0
HKD1_k127_5355231_1 PFAM SMC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000005048 220.0
HKD1_k127_5355231_2 Domain of unknown function (DUF4276) - - - 0.0000000000000000000000000000000000000000000008057 173.0
HKD1_k127_5355231_3 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0000000000000000000000000000000000000000003752 161.0
HKD1_k127_5355231_4 COG2189 Adenine specific DNA methylase Mod K07316 - 2.1.1.72 0.00000007736 54.0
HKD1_k127_5355742_0 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 323.0
HKD1_k127_5355742_1 von Willebrand factor, type A K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007753 273.0
HKD1_k127_5355742_2 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000003304 239.0
HKD1_k127_5359137_0 K02A2.6-like - - - 0.00000000000000000000000000000000000000000004256 182.0
HKD1_k127_5359137_1 dUTP diphosphatase activity. It is involved in the biological process described with dUTP metabolic process K01520 GO:0000166,GO:0000287,GO:0001889,GO:0003674,GO:0003824,GO:0004170,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010469,GO:0010646,GO:0010648,GO:0014070,GO:0015949,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0023051,GO:0023057,GO:0030545,GO:0030547,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032552,GO:0032556,GO:0034404,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0036094,GO:0042221,GO:0042975,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043497,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051259,GO:0051260,GO:0055086,GO:0061008,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0098772,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:2000272 3.6.1.23 0.000000000001301 76.0
HKD1_k127_5359677_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 314.0
HKD1_k127_5359677_1 Protein involved in hydrolase activity - - - 0.0000000000000000000002615 106.0
HKD1_k127_5363791_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1399.0
HKD1_k127_5363791_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 8.919e-239 749.0
HKD1_k127_5363791_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 507.0
HKD1_k127_5363791_3 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005639 282.0
HKD1_k127_5363791_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000001352 181.0
HKD1_k127_5363791_5 Site-specific recombinase - - - 0.00000000000000000000000000000005526 127.0
HKD1_k127_5363791_6 glutathione-regulated potassium exporter activity K02341,K03466 - 2.7.7.7 0.000000000000000000000000002347 130.0
HKD1_k127_5363791_7 Site-specific recombinase - - - 0.00008544 47.0
HKD1_k127_5364942_0 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004535 258.0
HKD1_k127_5364942_1 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.000000000000000000000000000000000000000000000000000001151 197.0
HKD1_k127_5364942_2 - - - - 0.000009527 51.0
HKD1_k127_5365978_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 541.0
HKD1_k127_5365978_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 517.0
HKD1_k127_5365978_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000009529 191.0
HKD1_k127_5365978_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000006156 189.0
HKD1_k127_5365978_12 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000006585 184.0
HKD1_k127_5365978_13 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000000006744 189.0
HKD1_k127_5365978_14 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000000007741 152.0
HKD1_k127_5365978_15 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000008534 150.0
HKD1_k127_5365978_16 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000000000000009142 140.0
HKD1_k127_5365978_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001489 143.0
HKD1_k127_5365978_18 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000000000000000000000377 130.0
HKD1_k127_5365978_19 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000000198 100.0
HKD1_k127_5365978_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 453.0
HKD1_k127_5365978_20 amine dehydrogenase activity K21449 - - 0.000000000000000001145 102.0
HKD1_k127_5365978_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 372.0
HKD1_k127_5365978_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 357.0
HKD1_k127_5365978_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 303.0
HKD1_k127_5365978_6 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000016 259.0
HKD1_k127_5365978_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000005705 240.0
HKD1_k127_5365978_8 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008478 256.0
HKD1_k127_5365978_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000006399 198.0
HKD1_k127_5367449_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 303.0
HKD1_k127_5367449_1 Hypothetical glycosyl hydrolase 6 - - - 0.000000000000000000000000000000000001538 160.0
HKD1_k127_5377201_0 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 474.0
HKD1_k127_5377201_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 396.0
HKD1_k127_5377201_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000001106 61.0
HKD1_k127_5377201_11 PilZ domain - - - 0.00006319 49.0
HKD1_k127_5377201_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
HKD1_k127_5377201_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002884 270.0
HKD1_k127_5377201_4 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000003887 235.0
HKD1_k127_5377201_5 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000000000000000000000000000000000000000000000000000002356 223.0
HKD1_k127_5377201_6 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000002861 230.0
HKD1_k127_5377201_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000001047 115.0
HKD1_k127_5377201_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000005215 106.0
HKD1_k127_5377201_9 RNA-binding protein containing a PIN domain K06962 - - 0.0000000001816 68.0
HKD1_k127_5380243_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1409.0
HKD1_k127_5380243_1 carboxylic acid catabolic process K18334 - 4.2.1.68 7.533e-223 696.0
HKD1_k127_5380243_2 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 380.0
HKD1_k127_5380243_3 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 341.0
HKD1_k127_5380243_4 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882,K00917 - 2.7.1.144,2.7.1.56 0.00000000000000000000000000000000000000000000001783 183.0
HKD1_k127_5380243_5 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.00000000000000000000003503 106.0
HKD1_k127_5393339_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 460.0
HKD1_k127_5393339_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000001007 190.0
HKD1_k127_5393339_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000008294 137.0
HKD1_k127_5393339_3 CAAX protease self-immunity K07052 - - 0.00000009437 57.0
HKD1_k127_5403389_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 362.0
HKD1_k127_5403389_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000007931 158.0
HKD1_k127_5403389_2 Sigma-70 factor, region 1.1 K03086 - - 0.00002085 55.0
HKD1_k127_5406197_0 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000009455 295.0
HKD1_k127_5406197_1 Planctomycete cytochrome C - - - 0.00007388 50.0
HKD1_k127_5425991_0 class II (D K K01876,K09759,K22503 - 6.1.1.12,6.1.1.23 4.358e-200 633.0
HKD1_k127_5440907_0 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 489.0
HKD1_k127_5444546_0 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 624.0
HKD1_k127_5444546_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 400.0
HKD1_k127_5444546_2 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000378 288.0
HKD1_k127_5444546_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000001126 179.0
HKD1_k127_5444546_4 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000006389 128.0
HKD1_k127_5444546_5 FR47-like protein - - - 0.00000001195 59.0
HKD1_k127_5444546_6 COG1918 Fe2 transport system protein A K04758 - - 0.00006664 48.0
HKD1_k127_5463044_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 506.0
HKD1_k127_5463044_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 347.0
HKD1_k127_5463044_2 deoxyhypusine monooxygenase activity K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000229 168.0
HKD1_k127_5463044_3 Acetyltransferase (GNAT) domain K03824 - - 0.00000000000000000000000000000000000000001443 158.0
HKD1_k127_5474772_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 437.0
HKD1_k127_5492598_0 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 334.0
HKD1_k127_5492598_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004374 271.0
HKD1_k127_5492598_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000009925 161.0
HKD1_k127_5493037_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 311.0
HKD1_k127_5493037_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 291.0
HKD1_k127_5493037_2 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000001062 191.0
HKD1_k127_5493037_3 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000006934 161.0
HKD1_k127_5493037_4 Protein of unknown function (DUF983) - - - 0.000000000000000002744 89.0
HKD1_k127_5506779_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.278e-304 944.0
HKD1_k127_5506779_1 Radical SAM - - - 3.644e-296 921.0
HKD1_k127_5506779_10 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000004133 186.0
HKD1_k127_5506779_11 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000001306 135.0
HKD1_k127_5506779_12 ATP-dependent protease La (LON) substrate-binding domain - - - 0.000000000000000000000000000000007892 135.0
HKD1_k127_5506779_13 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.0000000000000000000000000002602 126.0
HKD1_k127_5506779_14 ATP-binding region, ATPase domain protein - - - 0.000000006599 58.0
HKD1_k127_5506779_15 JAB/MPN domain - - - 0.00000152 50.0
HKD1_k127_5506779_2 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 1.663e-207 653.0
HKD1_k127_5506779_3 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 3.553e-203 643.0
HKD1_k127_5506779_4 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 571.0
HKD1_k127_5506779_5 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 546.0
HKD1_k127_5506779_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 545.0
HKD1_k127_5506779_7 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 456.0
HKD1_k127_5506779_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 321.0
HKD1_k127_5506779_9 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000006943 249.0
HKD1_k127_5512714_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 2.906e-309 964.0
HKD1_k127_5512714_1 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 578.0
HKD1_k127_5512714_10 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003873 254.0
HKD1_k127_5512714_11 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.000000000000000000000000000000000000000000000007827 182.0
HKD1_k127_5512714_12 mannose-6-phosphate isomerase K01809,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000001962 141.0
HKD1_k127_5512714_13 Smr domain - - - 0.00000000000000000000000001581 111.0
HKD1_k127_5512714_14 - - - - 0.00000000000000002986 85.0
HKD1_k127_5512714_15 pfam rdd - - - 0.0000000000003946 81.0
HKD1_k127_5512714_16 general secretion pathway protein K02456,K02650 - - 0.000026 53.0
HKD1_k127_5512714_2 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 485.0
HKD1_k127_5512714_3 PFAM delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 459.0
HKD1_k127_5512714_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 423.0
HKD1_k127_5512714_5 PFAM Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 396.0
HKD1_k127_5512714_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 338.0
HKD1_k127_5512714_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 321.0
HKD1_k127_5512714_8 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000156 286.0
HKD1_k127_5512714_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000004953 263.0
HKD1_k127_5514906_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 5.621e-226 707.0
HKD1_k127_5514906_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 616.0
HKD1_k127_5514906_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 610.0
HKD1_k127_5514906_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 516.0
HKD1_k127_5514906_4 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 319.0
HKD1_k127_5520825_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000003145 192.0
HKD1_k127_5520825_1 3-oxoacyl-ACP reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000006652 192.0
HKD1_k127_5520825_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000001043 199.0
HKD1_k127_5520825_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000004791 161.0
HKD1_k127_5562332_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 527.0
HKD1_k127_5562332_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 432.0
HKD1_k127_5562332_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 299.0
HKD1_k127_5562332_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 300.0
HKD1_k127_5562332_4 Transcriptional regulator - - - 0.00000000000000000000000000000000004125 138.0
HKD1_k127_5562332_5 PFAM Major Facilitator Superfamily K08223 - - 0.000002014 51.0
HKD1_k127_5566038_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000009405 197.0
HKD1_k127_5566038_1 Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N-terminus K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000001108 169.0
HKD1_k127_5566038_3 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000001519 62.0
HKD1_k127_5571029_0 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 411.0
HKD1_k127_5571029_1 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000000000000000001044 198.0
HKD1_k127_5572393_0 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000517 231.0
HKD1_k127_5572393_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000002331 218.0
HKD1_k127_5572393_2 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000001635 213.0
HKD1_k127_5572393_3 - K07018 - - 0.00000000000000000000000000000000000000008597 159.0
HKD1_k127_5572393_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000007066 126.0
HKD1_k127_5572393_5 PFAM SpoVT AbrB - - - 0.000000000000009321 76.0
HKD1_k127_5572393_6 membrane - - - 0.00000000000008635 71.0
HKD1_k127_5579401_0 xylulokinase activity K00848,K00851,K00854 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.12,2.7.1.17,2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 442.0
HKD1_k127_5579401_1 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) K08965 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009853,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016984,GO:0043094,GO:0044237 5.3.2.5 0.0000000000000000000000000000000000007437 148.0
HKD1_k127_5590163_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 - - 4.483e-197 629.0
HKD1_k127_5590163_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001774 231.0
HKD1_k127_5597887_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 336.0
HKD1_k127_5597887_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000118 267.0
HKD1_k127_5597887_2 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.0000000000000000000000000000000000000000000000000005508 190.0
HKD1_k127_5597887_3 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000002369 147.0
HKD1_k127_5598696_0 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 349.0
HKD1_k127_5598696_1 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 288.0
HKD1_k127_5598696_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
HKD1_k127_5598696_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000003193 261.0
HKD1_k127_5598696_4 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000003668 84.0
HKD1_k127_5605907_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 340.0
HKD1_k127_5605907_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 327.0
HKD1_k127_5605907_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000004137 246.0
HKD1_k127_5609512_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 504.0
HKD1_k127_5609512_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 422.0
HKD1_k127_5609512_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 401.0
HKD1_k127_5609512_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 383.0
HKD1_k127_5609512_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000001958 192.0
HKD1_k127_5609512_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000008635 184.0
HKD1_k127_5612073_0 COG COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit Energy production and conversion K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 437.0
HKD1_k127_5612073_1 DeoC/LacD family aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 351.0
HKD1_k127_5612073_2 transcriptional K03436 - - 0.00000000000000000000000000000000000000000001806 171.0
HKD1_k127_5612073_3 belongs to the carbohydrate kinase PfkB family K00882,K16370 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0008662,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019320,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.11,2.7.1.56 0.0000000000000000000000000009619 124.0
HKD1_k127_5612073_4 alcohol dehydrogenase K19956 - - 0.0000000000000000000007469 106.0
HKD1_k127_5617152_0 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 304.0
HKD1_k127_5617152_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 310.0
HKD1_k127_5623159_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.088e-203 660.0
HKD1_k127_5623159_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 393.0
HKD1_k127_5623159_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000003005 252.0
HKD1_k127_5623159_3 Peptidase family M50 - - - 0.0000000000000000000000002728 108.0
HKD1_k127_5623159_4 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000000006279 59.0
HKD1_k127_5651043_0 PFAM Carbohydrate kinase K00853 - 2.7.1.16 1.848e-227 709.0
HKD1_k127_5651043_1 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 473.0
HKD1_k127_5651043_2 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 414.0
HKD1_k127_5651043_3 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000003067 246.0
HKD1_k127_5653283_0 metallocarboxypeptidase activity K01206,K01218 - 3.2.1.51,3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 512.0
HKD1_k127_5653283_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002198 267.0
HKD1_k127_5653283_2 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000001041 193.0
HKD1_k127_5653283_3 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000002259 169.0
HKD1_k127_5653283_4 OsmC-like protein - - - 0.00000000000000000000000000000000000001219 150.0
HKD1_k127_5653283_5 - - - - 0.0000000000000000000000000000000000003221 151.0
HKD1_k127_5653283_6 electron transfer activity K03521 - - 0.0000000000000000000000000000002912 126.0
HKD1_k127_5653283_7 Putative zinc-finger - - - 0.0000000000003344 72.0
HKD1_k127_5653283_8 - - - - 0.00000003783 62.0
HKD1_k127_5653996_0 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 496.0
HKD1_k127_5653996_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
HKD1_k127_5653996_2 Thioredoxin K05838 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - 0.0000000000000000000000000000000000005693 145.0
HKD1_k127_5653996_3 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000002039 143.0
HKD1_k127_5653996_4 Filamentation induced by cAMP protein fic - - - 0.00000000000009695 80.0
HKD1_k127_5681605_0 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 587.0
HKD1_k127_5681605_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 536.0
HKD1_k127_5681605_2 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 501.0
HKD1_k127_5681605_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 344.0
HKD1_k127_5681605_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008819 278.0
HKD1_k127_5681605_5 PFAM FecR protein - - - 0.000000000000000000000000000000000000000001174 164.0
HKD1_k127_5681605_6 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000555 147.0
HKD1_k127_5681605_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000002153 119.0
HKD1_k127_5681605_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000003635 102.0
HKD1_k127_5681605_9 shape-determining protein MreD K03571 - - 0.0000000001215 68.0
HKD1_k127_5702944_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 417.0
HKD1_k127_5702944_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000001123 146.0
HKD1_k127_5719923_0 PFAM type III restriction protein res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 607.0
HKD1_k127_5719923_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 380.0
HKD1_k127_5722963_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 582.0
HKD1_k127_5722963_1 - - - - 0.00000000000000000000000000000000000000000000000521 175.0
HKD1_k127_5722963_2 PFAM Acyl-CoA dehydrogenase K09456 - - 0.0000003779 53.0
HKD1_k127_5735218_0 Histidine kinase - - - 5.795e-275 874.0
HKD1_k127_5735218_1 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 600.0
HKD1_k127_5735218_2 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 582.0
HKD1_k127_5735218_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000002624 128.0
HKD1_k127_5763601_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1289.0
HKD1_k127_5763601_1 Belongs to the IlvD Edd family K22396 - 4.2.1.82 3.925e-301 935.0
HKD1_k127_5763601_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 340.0
HKD1_k127_5763601_3 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002557 252.0
HKD1_k127_5763601_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000205 235.0
HKD1_k127_5763601_5 2-keto-3-deoxy-galactonokinase - - - 0.0000000000000000000000000000000000000000000000002678 188.0
HKD1_k127_5763601_6 von Willebrand factor, type A - - - 0.000000000000000000003828 105.0
HKD1_k127_5763601_8 Transcriptional regulator, DeoR family K21601 - - 0.000000006659 66.0
HKD1_k127_5782215_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 477.0
HKD1_k127_5782215_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 423.0
HKD1_k127_5782215_2 IMS family HHH motif K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 291.0
HKD1_k127_5782215_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000378 248.0
HKD1_k127_57837_0 Mandelate racemase muconate lactonizing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002678 287.0
HKD1_k127_57837_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000005156 195.0
HKD1_k127_57837_2 nucleoside hydrolase - - - 0.00000000000000000000000000000000000000000000000004676 193.0
HKD1_k127_57837_3 Pfam Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000000000002713 127.0
HKD1_k127_57837_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000001044 99.0
HKD1_k127_57837_5 Glycosyl hydrolase family 53 - - - 0.0000002657 57.0
HKD1_k127_5789737_0 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 396.0
HKD1_k127_5789737_1 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 355.0
HKD1_k127_5789737_2 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001712 288.0
HKD1_k127_5798132_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 404.0
HKD1_k127_5798132_1 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 379.0
HKD1_k127_5798132_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001195 270.0
HKD1_k127_5798132_3 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001702 273.0
HKD1_k127_5798132_4 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000009201 198.0
HKD1_k127_5798132_5 membrane-bound metal-dependent hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000001184 190.0
HKD1_k127_5798132_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000001126 153.0
HKD1_k127_5798132_7 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000003275 105.0
HKD1_k127_5798132_8 - - - - 0.000002213 55.0
HKD1_k127_5798678_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 2.743e-196 621.0
HKD1_k127_5798678_1 Protein tyrosine kinase - - - 0.0000003737 63.0
HKD1_k127_5803582_0 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000289 241.0
HKD1_k127_5803582_1 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.00000000000000000000000000000009484 143.0
HKD1_k127_5803582_2 endo-1,4-beta-xylanase activity - GO:0005575,GO:0005576 - 0.0000000000000000003102 102.0
HKD1_k127_5803582_3 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 0.0004131 46.0
HKD1_k127_5806013_0 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001224 273.0
HKD1_k127_5806013_1 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000001378 117.0
HKD1_k127_5806013_2 HAD-hyrolase-like - - - 0.000000000005418 66.0
HKD1_k127_5806013_3 pseudouridine 5'-phosphatase activity - - - 0.000001665 54.0
HKD1_k127_5806013_4 alpha-galactosidase K07407 - 3.2.1.22 0.00001922 58.0
HKD1_k127_5813881_0 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 299.0
HKD1_k127_5813881_1 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000231 261.0
HKD1_k127_5813881_2 pfam nipsnap - - - 0.00000000000000000000000000000000000000000000005168 176.0
HKD1_k127_5813881_3 Protein conserved in bacteria - - - 0.000000273 58.0
HKD1_k127_5838357_0 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 1.29e-274 895.0
HKD1_k127_5838357_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.598e-203 662.0
HKD1_k127_5838357_10 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000002449 225.0
HKD1_k127_5838357_11 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000009091 157.0
HKD1_k127_5838357_12 ADP-glyceromanno-heptose 6-epimerase activity K00311 - 1.5.5.1 0.00000000000003459 74.0
HKD1_k127_5838357_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 557.0
HKD1_k127_5838357_3 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 405.0
HKD1_k127_5838357_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 406.0
HKD1_k127_5838357_5 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 366.0
HKD1_k127_5838357_6 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 335.0
HKD1_k127_5838357_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001928 239.0
HKD1_k127_5838357_8 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002214 247.0
HKD1_k127_5838357_9 ADP-glyceromanno-heptose 6-epimerase activity K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000003194 232.0
HKD1_k127_5838808_0 Tricorn protease homolog - - - 0.0 1377.0
HKD1_k127_5838808_1 Belongs to the ClpA ClpB family K03696 - - 0.0 1248.0
HKD1_k127_5838808_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 310.0
HKD1_k127_5838808_11 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 305.0
HKD1_k127_5838808_12 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009254,GO:0016787,GO:0016801,GO:0016803,GO:0016829,GO:0016835,GO:0030203,GO:0043170,GO:0046348,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901575 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 301.0
HKD1_k127_5838808_13 2-keto-3-deoxy-L-rhamnonate aldolase activity K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000479 245.0
HKD1_k127_5838808_14 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
HKD1_k127_5838808_15 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000273 214.0
HKD1_k127_5838808_16 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000003435 208.0
HKD1_k127_5838808_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000001372 194.0
HKD1_k127_5838808_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000001414 176.0
HKD1_k127_5838808_19 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000002276 147.0
HKD1_k127_5838808_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 2.586e-218 711.0
HKD1_k127_5838808_20 Participates in the control of copper homeostasis K06201 GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - 0.00000000000000000000000000001332 126.0
HKD1_k127_5838808_21 TonB C terminal - - - 0.0000000000000000003115 99.0
HKD1_k127_5838808_22 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000007662 94.0
HKD1_k127_5838808_23 Rhodanese Homology Domain - - - 0.000000000009172 66.0
HKD1_k127_5838808_3 Putative carbohydrate binding domain K12373 - 3.2.1.52 4.975e-216 696.0
HKD1_k127_5838808_4 Surface antigen variable number K07277 - - 2.036e-202 662.0
HKD1_k127_5838808_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 546.0
HKD1_k127_5838808_6 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000836 387.0
HKD1_k127_5838808_7 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 379.0
HKD1_k127_5838808_8 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 329.0
HKD1_k127_5838808_9 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 321.0
HKD1_k127_5844387_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 318.0
HKD1_k127_5844387_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 302.0
HKD1_k127_5844387_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000002569 69.0
HKD1_k127_5873044_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000008806 187.0
HKD1_k127_5879592_0 2-hydroxyglutaryl-CoA dehydratase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000001082 232.0
HKD1_k127_5879592_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000001519 140.0
HKD1_k127_5883084_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 4.874e-235 743.0
HKD1_k127_5883084_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 408.0
HKD1_k127_5883084_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000001182 261.0
HKD1_k127_5883084_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000004346 176.0
HKD1_k127_5883084_4 HemY protein K01153,K02498 - 3.1.21.3 0.00000000000001017 76.0
HKD1_k127_5883084_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000005184 76.0
HKD1_k127_5883084_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000008923 68.0
HKD1_k127_5883084_7 PFAM Transposase domain (DUF772) - - - 0.00001551 48.0
HKD1_k127_5905718_0 PFAM Type II secretion system protein E K02652 - - 9.635e-251 785.0
HKD1_k127_5905718_1 Belongs to the IlvD Edd family - - - 2.484e-244 767.0
HKD1_k127_5905718_10 - - - - 0.0000000004395 69.0
HKD1_k127_5905718_11 Pilus assembly protein, PilO - - - 0.00004278 53.0
HKD1_k127_5905718_2 Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 469.0
HKD1_k127_5905718_3 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 335.0
HKD1_k127_5905718_4 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
HKD1_k127_5905718_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000002959 175.0
HKD1_k127_5905718_6 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000007365 154.0
HKD1_k127_5905718_7 general secretion pathway protein - - - 0.0000000000000000000000005832 116.0
HKD1_k127_5905718_8 Pilus assembly protein K02662 - - 0.00000000001203 76.0
HKD1_k127_5913549_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 391.0
HKD1_k127_5913549_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 330.0
HKD1_k127_5913549_2 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000007803 206.0
HKD1_k127_5913549_3 Cytochrome c K03611 - - 0.0000000000000000000000000000000000000000000001494 175.0
HKD1_k127_5913549_4 KR domain K00046,K00059 - 1.1.1.100,1.1.1.69 0.000000000000000001785 91.0
HKD1_k127_5928427_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000008302 213.0
HKD1_k127_5928427_1 - - - - 0.0000002608 61.0
HKD1_k127_5936696_0 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
HKD1_k127_5936696_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 265.0
HKD1_k127_5936696_2 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000009432 144.0
HKD1_k127_5949654_0 Domain of unknown function (DUF4432) - - - 0.000000000000000000000000000000000000000000000000000000000000000005095 238.0
HKD1_k127_5949654_1 Enoyl-(Acyl carrier protein) reductase K00059,K18009,K19548 - 1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76 0.0000000000000000000000000000000000000000000000000000001106 204.0
HKD1_k127_5949654_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000005366 151.0
HKD1_k127_5956778_0 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 413.0
HKD1_k127_5956778_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 332.0
HKD1_k127_5989855_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 513.0
HKD1_k127_5989855_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 460.0
HKD1_k127_5989855_2 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 455.0
HKD1_k127_5989855_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 341.0
HKD1_k127_5989855_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006863 257.0
HKD1_k127_5989855_5 methyltransferase activity - - - 0.00000000000000000000000000000009571 129.0
HKD1_k127_600203_0 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 389.0
HKD1_k127_600203_1 MASE1 - - - 0.000000000000000000000000000000000000001826 154.0
HKD1_k127_6020266_0 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 377.0
HKD1_k127_6020266_1 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000006015 188.0
HKD1_k127_6020266_2 Domain of Unknown Function (DUF350) - - - 0.00000000000000000002585 92.0
HKD1_k127_6020266_3 - - - - 0.00000000002801 65.0
HKD1_k127_6023025_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 379.0
HKD1_k127_6023025_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 369.0
HKD1_k127_6023025_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000004449 60.0
HKD1_k127_6030415_0 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001924 222.0
HKD1_k127_6030415_1 General secretion pathway protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0002123 47.0
HKD1_k127_6037951_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 503.0
HKD1_k127_6037951_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 454.0
HKD1_k127_6037951_10 DGC domain K02437 - - 0.000000000000000000000000000000000002865 142.0
HKD1_k127_6037951_11 DGC domain - - - 0.000000000000000000000000000000002854 137.0
HKD1_k127_6037951_12 DGC domain - - - 0.00000000000000000000000003488 112.0
HKD1_k127_6037951_13 - - - - 0.00000000000000000000000007172 112.0
HKD1_k127_6037951_14 redox-active disulfide protein 2 - - - 0.00000000000000000001652 94.0
HKD1_k127_6037951_2 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 311.0
HKD1_k127_6037951_3 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000181 201.0
HKD1_k127_6037951_4 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000009861 182.0
HKD1_k127_6037951_5 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000000000002094 170.0
HKD1_k127_6037951_7 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000000000000008389 163.0
HKD1_k127_6037951_8 OsmC-like protein - - - 0.0000000000000000000000000000000000007644 144.0
HKD1_k127_6037951_9 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000001179 140.0
HKD1_k127_6041123_0 FAD binding domain K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 526.0
HKD1_k127_6041123_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 513.0
HKD1_k127_6041123_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 481.0
HKD1_k127_6041123_3 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 357.0
HKD1_k127_6041123_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 303.0
HKD1_k127_6041123_5 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000000000000005804 198.0
HKD1_k127_6041123_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000001774 186.0
HKD1_k127_6041123_7 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000005066 125.0
HKD1_k127_6050571_0 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 496.0
HKD1_k127_6050571_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 477.0
HKD1_k127_6050571_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 452.0
HKD1_k127_6050571_3 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000001483 269.0
HKD1_k127_6050571_4 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002017 195.0
HKD1_k127_6050571_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000001866 156.0
HKD1_k127_6050571_6 PilZ domain - - - 0.000006659 57.0
HKD1_k127_6050571_7 Glycosyltransferase family 87 - - - 0.00001244 57.0
HKD1_k127_6050571_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00003847 54.0
HKD1_k127_6050571_9 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0002224 51.0
HKD1_k127_6052013_0 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.000000000000000000000000003827 114.0
HKD1_k127_6052013_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000009526 110.0
HKD1_k127_6099164_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 8.123e-243 763.0
HKD1_k127_6099164_1 Radical SAM - - - 1.756e-216 690.0
HKD1_k127_6099164_10 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000001043 245.0
HKD1_k127_6099164_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002525 229.0
HKD1_k127_6099164_12 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000002234 193.0
HKD1_k127_6099164_13 heme binding K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000011 184.0
HKD1_k127_6099164_14 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000001785 152.0
HKD1_k127_6099164_15 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000002978 136.0
HKD1_k127_6099164_16 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000009498 116.0
HKD1_k127_6099164_17 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000002426 111.0
HKD1_k127_6099164_18 Regulatory protein, FmdB family - - - 0.00000001525 60.0
HKD1_k127_6099164_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665,K02619,K03342,K13503,K13950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 507.0
HKD1_k127_6099164_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 477.0
HKD1_k127_6099164_4 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 407.0
HKD1_k127_6099164_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 389.0
HKD1_k127_6099164_6 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 341.0
HKD1_k127_6099164_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 303.0
HKD1_k127_6099164_8 NUDIX domain K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 293.0
HKD1_k127_6099164_9 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006563 287.0
HKD1_k127_6110543_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 364.0
HKD1_k127_6110543_1 NAD+ synthase (glutamine-hydrolyzing) activity K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 344.0
HKD1_k127_6110543_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 302.0
HKD1_k127_6110543_3 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000004853 98.0
HKD1_k127_6110543_4 acyl carrier protein - - - 0.0000000000000338 81.0
HKD1_k127_6110543_6 KR domain - - - 0.00003106 49.0
HKD1_k127_611693_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1041.0
HKD1_k127_611693_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 305.0
HKD1_k127_611693_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000005968 123.0
HKD1_k127_6125958_0 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 344.0
HKD1_k127_6125958_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000003774 205.0
HKD1_k127_6125958_2 Methyltransferase K10218 - 4.1.3.17 0.00000000000000000000000000000001791 132.0
HKD1_k127_6126125_0 Belongs to the carbamoyltransferase HypF family K04656 - - 3.057e-242 769.0
HKD1_k127_6126125_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 576.0
HKD1_k127_6126125_2 Psort location Cytoplasmic, score 9.97 K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001449 247.0
HKD1_k127_6126125_3 COGs COG0680 Ni Fe-hydrogenase maturation factor K03605 - - 0.000000000000000000000000000000000000000000000002999 177.0
HKD1_k127_6126125_4 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000004051 158.0
HKD1_k127_6126125_5 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000005608 150.0
HKD1_k127_6126125_6 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000001925 134.0
HKD1_k127_6126125_7 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000000004942 117.0
HKD1_k127_6126125_8 Hydrogenase nickel incorporation protein hypA K04651 - - 0.000000000000000000000832 98.0
HKD1_k127_6134136_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.343e-265 826.0
HKD1_k127_6134136_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 523.0
HKD1_k127_6134136_10 PD-(D/E)XK nuclease superfamily - - - 0.00002939 48.0
HKD1_k127_6134136_2 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 383.0
HKD1_k127_6134136_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 366.0
HKD1_k127_6134136_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000006746 229.0
HKD1_k127_6134136_5 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000006769 165.0
HKD1_k127_6134136_6 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000001204 151.0
HKD1_k127_6134136_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000009979 141.0
HKD1_k127_6134136_8 PFAM Colicin V production K03558 - - 0.00000000000000000000000000392 117.0
HKD1_k127_6134136_9 Bacterial regulatory protein, Fis family - - - 0.00000000000008457 73.0
HKD1_k127_6136822_0 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 422.0
HKD1_k127_6136822_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 410.0
HKD1_k127_6136822_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 332.0
HKD1_k127_6136822_3 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000005205 206.0
HKD1_k127_6136822_4 sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000002492 190.0
HKD1_k127_6136822_5 Trehalose-phosphatase K16055 - 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000007287 149.0
HKD1_k127_6136822_6 protein kinase activity - - - 0.000001347 58.0
HKD1_k127_6137319_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1305.0
HKD1_k127_6137319_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.336e-211 663.0
HKD1_k127_6137319_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 567.0
HKD1_k127_6137319_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002474 269.0
HKD1_k127_6137319_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 258.0
HKD1_k127_6137319_5 Response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes K07712 - - 0.000001076 56.0
HKD1_k127_6140805_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 392.0
HKD1_k127_6140805_1 Argininosuccinate lyase C-terminal K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
HKD1_k127_6140805_2 CAAX protease self-immunity K07052 - - 0.0000000000000000644 88.0
HKD1_k127_6140805_3 Major facilitator superfamily - - - 0.0000000000000002477 81.0
HKD1_k127_6140805_4 Histidine kinase K07675 - 2.7.13.3 0.0000000346 65.0
HKD1_k127_6144930_0 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 320.0
HKD1_k127_6144930_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 319.0
HKD1_k127_6144930_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000001246 121.0
HKD1_k127_614731_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 441.0
HKD1_k127_614731_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
HKD1_k127_614731_2 Chromate transporter K07240 - - 0.000000000000000000000000000000001696 135.0
HKD1_k127_6149988_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.873e-210 662.0
HKD1_k127_6149988_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 539.0
HKD1_k127_6149988_10 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00001451 55.0
HKD1_k127_6149988_2 Glycosyl hydrolases family 28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 358.0
HKD1_k127_6149988_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005805 249.0
HKD1_k127_6149988_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000001193 208.0
HKD1_k127_6149988_5 - - - - 0.000000000000000000000000000000000000007345 166.0
HKD1_k127_6149988_6 arabinose efflux - - - 0.00000000000000000000000000505 125.0
HKD1_k127_6149988_7 - - - - 0.00000000000000000000005718 108.0
HKD1_k127_6149988_8 Cupin domain - - - 0.000000000001469 74.0
HKD1_k127_6149988_9 Fibronectin type III domain protein - - - 0.0000007594 58.0
HKD1_k127_6152553_0 Myosin-crossreactive antigen K10254 - 4.2.1.53 3.223e-258 811.0
HKD1_k127_6152553_1 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
HKD1_k127_6209744_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.946e-239 756.0
HKD1_k127_6209744_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 498.0
HKD1_k127_6209744_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000001878 80.0
HKD1_k127_6209744_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000001227 65.0
HKD1_k127_6209744_12 - - - - 0.0001484 47.0
HKD1_k127_6209744_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 438.0
HKD1_k127_6209744_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 392.0
HKD1_k127_6209744_4 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 312.0
HKD1_k127_6209744_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
HKD1_k127_6209744_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000002828 199.0
HKD1_k127_6209744_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000001881 146.0
HKD1_k127_6209744_8 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000006936 123.0
HKD1_k127_6209744_9 - - - - 0.0000000000000000001415 91.0
HKD1_k127_6212338_0 glutamate synthase alpha subunit K00265 - 1.4.1.13,1.4.1.14 0.0 2044.0
HKD1_k127_6212338_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.109e-291 907.0
HKD1_k127_6212338_2 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 7.319e-215 677.0
HKD1_k127_6212338_3 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 622.0
HKD1_k127_6212338_4 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 370.0
HKD1_k127_6212338_5 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000001285 241.0
HKD1_k127_6212338_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000002552 235.0
HKD1_k127_6212338_7 Yip1 domain - - - 0.0000000000000000000000000000000000000000001256 164.0
HKD1_k127_6212338_8 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000003738 148.0
HKD1_k127_6240244_0 heat shock protein binding K03686 - - 0.0000000000000000000000000000000000000000000000000000002958 201.0
HKD1_k127_6240244_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000004719 101.0
HKD1_k127_6240244_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000002434 93.0
HKD1_k127_6250696_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 439.0
HKD1_k127_6250696_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 430.0
HKD1_k127_6250696_10 Universal stress protein - - - 0.000000000000000000000000000001346 127.0
HKD1_k127_6250696_11 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000009155 68.0
HKD1_k127_6250696_12 - - - - 0.0000001396 56.0
HKD1_k127_6250696_13 SMART PDZ DHR GLGF domain protein K11749 - - 0.0001363 53.0
HKD1_k127_6250696_2 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 367.0
HKD1_k127_6250696_3 translation release factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009072 255.0
HKD1_k127_6250696_4 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000007493 181.0
HKD1_k127_6250696_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000283 179.0
HKD1_k127_6250696_6 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000001092 162.0
HKD1_k127_6250696_7 Cytochrome c - - - 0.0000000000000000000000000000000000003434 145.0
HKD1_k127_6250696_8 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000003279 151.0
HKD1_k127_6250696_9 Cytochrome c - - - 0.000000000000000000000000000000002009 133.0
HKD1_k127_6251980_0 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 548.0
HKD1_k127_6251980_1 VacB and RNase II family 3'-5' K12573 - - 0.00002471 48.0
HKD1_k127_6256532_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 473.0
HKD1_k127_6256532_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000001128 115.0
HKD1_k127_6256532_3 Bacterial Ig-like domain (group 3) K20276 - - 0.000000001682 70.0
HKD1_k127_6278806_0 aminopeptidase activity K07004 - - 0.000000000000000000000000000000000000000000000000000000000001987 226.0
HKD1_k127_6278806_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001604 223.0
HKD1_k127_6278806_2 DEAD DEAH box K03724 - - 0.0000002198 55.0
HKD1_k127_6280147_0 elongation factor G K02355 - - 1.472e-212 679.0
HKD1_k127_6280147_1 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 409.0
HKD1_k127_6280147_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 362.0
HKD1_k127_6280147_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 319.0
HKD1_k127_6280147_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 298.0
HKD1_k127_6280147_5 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000003366 198.0
HKD1_k127_6280147_6 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000001322 131.0
HKD1_k127_6280147_7 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.000000000000000000000000000361 126.0
HKD1_k127_6280147_8 Signal Transduction Histidine Kinase - - - 0.0000000000000000000000006713 121.0
HKD1_k127_6280147_9 Haloacid dehalogenase-like hydrolase K07025 - - 0.00002569 47.0
HKD1_k127_6280623_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 498.0
HKD1_k127_6287532_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 510.0
HKD1_k127_6287532_1 viral genome integration into host DNA K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000004086 231.0
HKD1_k127_6287532_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000009496 203.0
HKD1_k127_6287532_3 - - - - 0.000000000000001048 84.0
HKD1_k127_6299914_0 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 406.0
HKD1_k127_6299914_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000003959 90.0
HKD1_k127_6302594_0 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 577.0
HKD1_k127_6302594_1 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000002061 85.0
HKD1_k127_6302594_2 Oxidoreductase - - - 0.00000000000002281 73.0
HKD1_k127_630418_0 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 330.0
HKD1_k127_630418_1 Tellurite resistance protein TerB K05801 - - 0.00000004199 57.0
HKD1_k127_630418_2 Protein of unknown function (DUF1249) - - - 0.0000259 51.0
HKD1_k127_6308492_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 - 5.3.1.25,5.3.1.3 6.854e-279 864.0
HKD1_k127_6308492_1 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 410.0
HKD1_k127_6312891_0 cell redox homeostasis K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 559.0
HKD1_k127_6312891_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005174 239.0
HKD1_k127_6332544_0 Protein of unknown function (DUF1501) - - - 1.044e-238 743.0
HKD1_k127_6332544_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.09e-206 648.0
HKD1_k127_6332544_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 614.0
HKD1_k127_6332544_3 pentaerythritol trinitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 516.0
HKD1_k127_6332544_4 PFAM Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000001859 252.0
HKD1_k127_6332544_5 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000152 235.0
HKD1_k127_6332544_6 PFAM Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.000000000000000000000000000000000000000000000000001859 186.0
HKD1_k127_6332544_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000166 188.0
HKD1_k127_6332544_9 protein conserved in bacteria - - - 0.0000000000000000009571 94.0
HKD1_k127_6336527_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 317.0
HKD1_k127_6336527_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000278 231.0
HKD1_k127_6336527_2 haloacid dehalogenase-like hydrolase - - - 0.0000000011 59.0
HKD1_k127_6367335_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 411.0
HKD1_k127_6367335_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0001651 44.0
HKD1_k127_6368160_0 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 451.0
HKD1_k127_6368160_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 295.0
HKD1_k127_6368160_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000238 175.0
HKD1_k127_6381572_0 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 3.673e-258 807.0
HKD1_k127_6381572_1 Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
HKD1_k127_6381572_2 Restriction endonuclease - - - 0.00000000000000000000000000000000006087 137.0
HKD1_k127_6389086_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.675e-258 811.0
HKD1_k127_6389564_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 464.0
HKD1_k127_6389564_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000006422 121.0
HKD1_k127_6391315_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 473.0
HKD1_k127_6391315_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 457.0
HKD1_k127_6391315_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 254.0
HKD1_k127_6391315_11 PFAM aminotransferase, class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000001322 246.0
HKD1_k127_6391315_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000009082 186.0
HKD1_k127_6391315_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000002909 160.0
HKD1_k127_6391315_14 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000002935 128.0
HKD1_k127_6391315_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000001089 81.0
HKD1_k127_6391315_16 PFAM PHP domain K07053 - 3.1.3.97 0.0000415 51.0
HKD1_k127_6391315_17 SMART phosphoesterase PHP domain protein - - - 0.00007723 49.0
HKD1_k127_6391315_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 394.0
HKD1_k127_6391315_3 ABC transporter, solute-binding protein K11069,K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 391.0
HKD1_k127_6391315_4 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 370.0
HKD1_k127_6391315_5 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 338.0
HKD1_k127_6391315_6 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 325.0
HKD1_k127_6391315_7 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 312.0
HKD1_k127_6391315_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001831 281.0
HKD1_k127_6391315_9 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009736 265.0
HKD1_k127_6399554_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 290.0
HKD1_k127_6399554_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002535 233.0
HKD1_k127_6401441_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 396.0
HKD1_k127_6401441_1 Domain of unknown function (DUF4432) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004088 259.0
HKD1_k127_6401441_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000008275 234.0
HKD1_k127_6401441_3 cobalamin binding - - - 0.0000000000000000000000000000000000000000000003123 181.0
HKD1_k127_6401441_4 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000006865 149.0
HKD1_k127_6401441_5 mannose metabolic process K01191 - 3.2.1.24 0.0000000000003936 83.0
HKD1_k127_6404489_0 slime layer polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 412.0
HKD1_k127_6404489_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 309.0
HKD1_k127_6404489_10 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000001753 151.0
HKD1_k127_6404489_11 Belongs to the enoyl-CoA hydratase isomerase family K05607 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.18 0.00000000000000000000000000000006644 135.0
HKD1_k127_6404489_12 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000006736 136.0
HKD1_k127_6404489_13 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000137 131.0
HKD1_k127_6404489_14 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000001438 126.0
HKD1_k127_6404489_15 Melibiase K07407 - 3.2.1.22 0.0000000006619 70.0
HKD1_k127_6404489_16 - - - - 0.00000001421 61.0
HKD1_k127_6404489_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000002823 52.0
HKD1_k127_6404489_2 Male sterility protein K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 325.0
HKD1_k127_6404489_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002099 276.0
HKD1_k127_6404489_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003306 276.0
HKD1_k127_6404489_5 Male sterility protein K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002131 269.0
HKD1_k127_6404489_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
HKD1_k127_6404489_7 VIT family - - - 0.000000000000000000000000000000000000000000000000003161 184.0
HKD1_k127_6404489_8 VIT family - - - 0.000000000000000000000000000000000000000001103 159.0
HKD1_k127_6404489_9 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000001878 155.0
HKD1_k127_6404638_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1701.0
HKD1_k127_6404638_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 409.0
HKD1_k127_6404638_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 316.0
HKD1_k127_6404638_3 - - - - 0.00000000000000004452 85.0
HKD1_k127_6406005_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1666.0
HKD1_k127_6406005_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1320.0
HKD1_k127_6406005_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 464.0
HKD1_k127_6406005_3 thiolester hydrolase activity K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000002615 161.0
HKD1_k127_6406005_4 MarR family - - - 0.00000000000000000000000000000000004223 140.0
HKD1_k127_6406005_5 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000005548 85.0
HKD1_k127_6406422_0 COGs COG1228 Imidazolonepropionase and related amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 490.0
HKD1_k127_6406422_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 472.0
HKD1_k127_6406422_2 COGs COG1228 Imidazolonepropionase and related amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 374.0
HKD1_k127_6406422_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001899 283.0
HKD1_k127_6406422_4 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000001434 247.0
HKD1_k127_6406422_5 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000002203 210.0
HKD1_k127_6406422_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000002581 151.0
HKD1_k127_6406422_7 CHRD domain - - - 0.000000000000000000000000229 112.0
HKD1_k127_6406422_8 - - - - 0.00001359 48.0
HKD1_k127_6415499_0 Gluconolactonase K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 603.0
HKD1_k127_6415499_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 503.0
HKD1_k127_6415499_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001784 288.0
HKD1_k127_6415499_3 - - - - 0.00000000000000000000000000000000000000000000000000000000002877 209.0
HKD1_k127_644433_0 Planctomycete cytochrome C - - - 5.163e-262 842.0
HKD1_k127_644433_1 sulfuric ester hydrolase activity K01992 - - 6.144e-226 707.0
HKD1_k127_644433_10 pyridoxamine 5-phosphate - - - 0.000001531 56.0
HKD1_k127_644433_2 Epoxide hydrolase N terminus K21159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 557.0
HKD1_k127_644433_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 505.0
HKD1_k127_644433_4 PFAM Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006824 251.0
HKD1_k127_644433_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001013 240.0
HKD1_k127_644433_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000001135 228.0
HKD1_k127_644433_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000002344 199.0
HKD1_k127_644433_8 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K01768 - 4.6.1.1 0.00000000000000000000000000000005596 131.0
HKD1_k127_6472643_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 449.0
HKD1_k127_6472643_1 transposase activity K07483,K07497 - - 0.00000000000000006911 84.0
HKD1_k127_6472643_2 Protein of unknown function (DUF445) - - - 0.0000000000000002905 79.0
HKD1_k127_648092_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 6.059e-211 666.0
HKD1_k127_648092_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 445.0
HKD1_k127_648092_2 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005469 272.0
HKD1_k127_648092_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000009481 190.0
HKD1_k127_648092_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000728 104.0
HKD1_k127_6481913_0 Protein of unknown function (DUF1549) - - - 6.508e-289 926.0
HKD1_k127_6481913_1 Putative Na+/H+ antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002874 262.0
HKD1_k127_6486636_0 Glycosyl hydrolases family 38 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002475 277.0
HKD1_k127_6486636_1 COG COG0383 Alpha-mannosidase - - - 0.000000000000000000000000000000000000000000000000000000003212 220.0
HKD1_k127_6492120_0 Carboxypeptidase regulatory-like domain - - - 2.276e-229 737.0
HKD1_k127_6492120_1 Phospholipid methyltransferase K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 317.0
HKD1_k127_6492120_2 Signal Transduction Histidine Kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 319.0
HKD1_k127_6492120_3 Participates in transcription elongation, termination and antitermination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004299 259.0
HKD1_k127_6496165_0 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 335.0
HKD1_k127_6496165_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000009171 145.0
HKD1_k127_6496165_2 CAAX protease self-immunity - - - 0.0000000000000000000000000000000002485 145.0
HKD1_k127_6496703_0 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 390.0
HKD1_k127_6498969_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 451.0
HKD1_k127_6498969_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 321.0
HKD1_k127_6498969_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 314.0
HKD1_k127_6498969_3 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004837 264.0
HKD1_k127_6498969_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000009073 209.0
HKD1_k127_6498969_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000002053 128.0
HKD1_k127_6498969_6 Cold shock protein K03704 - - 0.000006537 52.0
HKD1_k127_6514749_0 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 6.608e-287 918.0
HKD1_k127_6514749_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 336.0
HKD1_k127_6514749_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000001615 202.0
HKD1_k127_6514749_3 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000001094 154.0
HKD1_k127_6520887_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.19e-259 809.0
HKD1_k127_6520887_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000001286 50.0
HKD1_k127_6526732_0 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 554.0
HKD1_k127_6526732_1 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006575 290.0
HKD1_k127_6526732_2 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000002909 160.0
HKD1_k127_6526732_3 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.0000000000000000000000000000000001236 154.0
HKD1_k127_6526732_5 Cytochrome c K00406,K08906 - - 0.00000002927 60.0
HKD1_k127_6558376_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 1.526e-203 644.0
HKD1_k127_6558376_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000006979 199.0
HKD1_k127_656690_0 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 619.0
HKD1_k127_656690_1 L-rhamnose-proton symport protein (RhaT) K02856 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000172 291.0
HKD1_k127_6582105_0 Cytochrome c - - - 0.0 1215.0
HKD1_k127_6582105_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 2.863e-275 856.0
HKD1_k127_6582105_10 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001048 254.0
HKD1_k127_6582105_11 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000007078 249.0
HKD1_k127_6582105_12 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000001041 243.0
HKD1_k127_6582105_13 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000000000000000000000000000009146 179.0
HKD1_k127_6582105_14 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000009173 154.0
HKD1_k127_6582105_15 SCO1/SenC K07152,K08976 - - 0.00000000000000000002254 95.0
HKD1_k127_6582105_16 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000002267 91.0
HKD1_k127_6582105_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 508.0
HKD1_k127_6582105_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 488.0
HKD1_k127_6582105_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 403.0
HKD1_k127_6582105_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 302.0
HKD1_k127_6582105_6 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 289.0
HKD1_k127_6582105_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 270.0
HKD1_k127_6582105_8 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000008597 265.0
HKD1_k127_6582105_9 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002914 255.0
HKD1_k127_6585843_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1034.0
HKD1_k127_6585843_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006773 248.0
HKD1_k127_6585843_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000001537 233.0
HKD1_k127_6585843_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000005155 234.0
HKD1_k127_6585843_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000003474 222.0
HKD1_k127_6585843_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000007279 83.0
HKD1_k127_6587510_0 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 390.0
HKD1_k127_6587510_1 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 297.0
HKD1_k127_6587510_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006666 283.0
HKD1_k127_6587510_3 - - - - 0.00000000000000000000000000000000000000001236 159.0
HKD1_k127_6587510_4 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000000000005926 154.0
HKD1_k127_6587510_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000003981 130.0
HKD1_k127_6587510_6 Sodium:solute symporter family - - - 0.0000000000000000000003629 100.0
HKD1_k127_6589924_0 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008171 542.0
HKD1_k127_6596175_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 555.0
HKD1_k127_6596175_1 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 392.0
HKD1_k127_6596175_2 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000000000000000004941 173.0
HKD1_k127_661142_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
HKD1_k127_661142_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000002182 169.0
HKD1_k127_661142_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000127 120.0
HKD1_k127_6625074_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 2.133e-208 668.0
HKD1_k127_6625074_1 Membrane-bound dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 595.0
HKD1_k127_6625074_10 Protein of unknown function (DUF4230) - - - 0.00000001079 65.0
HKD1_k127_6625074_2 alcohol dehydrogenase K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 479.0
HKD1_k127_6625074_3 Orotidine 5'-phosphate decarboxylase / HUMPS family K08093 - 4.1.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 358.0
HKD1_k127_6625074_4 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 272.0
HKD1_k127_6625074_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000002444 246.0
HKD1_k127_6625074_6 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 247.0
HKD1_k127_6625074_7 Belongs to the carbohydrate kinase PfkB family K00847 GO:0003674,GO:0003824,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005911,GO:0005975,GO:0005996,GO:0006000,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008865,GO:0009058,GO:0009506,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016051,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019752,GO:0030054,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046835,GO:0055044,GO:0071704,GO:0072330,GO:1901576 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
HKD1_k127_6625074_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000006909 186.0
HKD1_k127_6625074_9 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000000141 148.0
HKD1_k127_6630006_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 6.604e-196 619.0
HKD1_k127_6630006_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000005578 167.0
HKD1_k127_6630006_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000001387 72.0
HKD1_k127_6632676_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 454.0
HKD1_k127_6637896_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1472.0
HKD1_k127_6637896_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 461.0
HKD1_k127_6637896_2 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 451.0
HKD1_k127_6637896_3 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 426.0
HKD1_k127_6637896_4 Uncharacterised conserved protein (DUF2156) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007263 286.0
HKD1_k127_6637896_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000002913 196.0
HKD1_k127_6637896_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000001094 137.0
HKD1_k127_6637896_7 acr, cog1993 K09137 - - 0.00000000000000000000000000004037 120.0
HKD1_k127_6637896_8 SNARE associated Golgi protein - - - 0.0000000000000000000000322 116.0
HKD1_k127_6638122_0 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000006342 118.0
HKD1_k127_6638122_1 Integrase core domain K07497 - - 0.0000002077 52.0
HKD1_k127_6638427_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 310.0
HKD1_k127_6638427_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000001186 184.0
HKD1_k127_6638427_2 Sporulation and spore germination - - - 0.000000000000000000000000003262 119.0
HKD1_k127_6638427_3 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000357 107.0
HKD1_k127_6640367_0 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 492.0
HKD1_k127_6640367_1 glycerol kinase activity K11214 GO:0002237,GO:0002682,GO:0002694,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010033,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0031347,GO:0032101,GO:0032496,GO:0033993,GO:0034097,GO:0034641,GO:0035962,GO:0035963,GO:0042221,GO:0043030,GO:0043207,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048583,GO:0050277,GO:0050727,GO:0050789,GO:0050794,GO:0050865,GO:0050896,GO:0051156,GO:0051186,GO:0051704,GO:0051707,GO:0051716,GO:0055086,GO:0065007,GO:0070670,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071353,GO:0071396,GO:0071704,GO:0072524,GO:0080134,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1901701 2.7.1.14 0.00000000000000000000000000000000000000000001272 175.0
HKD1_k127_6645481_0 ASPIC and UnbV - - - 1.2e-230 756.0
HKD1_k127_6645481_1 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000009226 157.0
HKD1_k127_6646537_0 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 522.0
HKD1_k127_6646537_1 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 333.0
HKD1_k127_6646537_2 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000001051 154.0
HKD1_k127_6646537_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000233 124.0
HKD1_k127_6646537_4 GYD domain - - - 0.0000000000000000000000000002368 117.0
HKD1_k127_6646537_5 ASPIC and UnbV - - - 0.00000000000000000000000009721 108.0
HKD1_k127_6654530_0 Protein of unknown function, DUF255 K06888 - - 1.589e-233 743.0
HKD1_k127_6654530_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 387.0
HKD1_k127_6654530_2 Type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000309 153.0
HKD1_k127_6654530_3 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.000000000000000000000000000000000000002253 162.0
HKD1_k127_6654530_4 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000001549 100.0
HKD1_k127_6655243_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 384.0
HKD1_k127_6655243_1 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 329.0
HKD1_k127_6658530_0 - - - - 1.147e-238 755.0
HKD1_k127_6658530_1 PFAM FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 445.0
HKD1_k127_6658530_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 436.0
HKD1_k127_6658530_3 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000526 184.0
HKD1_k127_6658530_4 TrkA-C domain K10716 - - 0.000000000001965 71.0
HKD1_k127_6658530_5 DnaJ C terminal domain K03686 - - 0.00000001475 67.0
HKD1_k127_6667339_0 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HKD1_k127_6667339_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000001497 202.0
HKD1_k127_6667339_2 Helix-turn-helix domain - - - 0.000000000000000000000008865 102.0
HKD1_k127_6676980_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 418.0
HKD1_k127_6676980_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
HKD1_k127_6694752_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 460.0
HKD1_k127_6694752_1 sulfate transport system, permease K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 297.0
HKD1_k127_6694752_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000001884 166.0
HKD1_k127_6694752_3 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000005984 170.0
HKD1_k127_6695051_0 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 464.0
HKD1_k127_6695051_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000002114 126.0
HKD1_k127_6701436_0 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 0.0 1073.0
HKD1_k127_6701436_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1020.0
HKD1_k127_6701436_2 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 478.0
HKD1_k127_6701436_3 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 349.0
HKD1_k127_6701436_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 302.0
HKD1_k127_6701436_5 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
HKD1_k127_6701436_6 pfam abc K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000101 284.0
HKD1_k127_6701436_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000197 50.0
HKD1_k127_6707155_0 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 294.0
HKD1_k127_6707155_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000003043 181.0
HKD1_k127_6707155_2 - - - - 0.00000000000000000000000000000000000000000000002499 172.0
HKD1_k127_6707155_3 PFAM Nitroreductase family - - - 0.0000007176 53.0
HKD1_k127_671075_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 483.0
HKD1_k127_671075_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 434.0
HKD1_k127_671075_2 Protein of unknown function (DUF1501) - - - 0.00002173 48.0
HKD1_k127_672568_0 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008105 276.0
HKD1_k127_672568_1 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000001412 104.0
HKD1_k127_672568_2 - - - - 0.00000000000000004837 83.0
HKD1_k127_672568_3 - - - - 0.0000000000008375 69.0
HKD1_k127_672568_4 - - - - 0.00000174 51.0
HKD1_k127_6727477_0 PFAM FAD linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 444.0
HKD1_k127_6727477_1 - - - - 0.000000000000000000000006919 111.0
HKD1_k127_6727477_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.000000000004048 67.0
HKD1_k127_6727477_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00001418 50.0
HKD1_k127_6784757_0 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000004354 193.0
HKD1_k127_6784757_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000001026 171.0
HKD1_k127_6784757_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000003381 131.0
HKD1_k127_6795491_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 462.0
HKD1_k127_6795491_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 343.0
HKD1_k127_6795491_2 Yqey-like protein K09117 - - 0.00000000000000000000000000000002401 131.0
HKD1_k127_6795491_3 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000002673 94.0
HKD1_k127_6795491_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000007298 89.0
HKD1_k127_68003_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000001604 102.0
HKD1_k127_68003_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000007185 92.0
HKD1_k127_6806254_0 AMP-binding enzyme C-terminal domain - - - 3.97e-297 942.0
HKD1_k127_6806254_1 N-acetyltransferase K00675 - 2.3.1.118 0.0000000002409 65.0
HKD1_k127_6810498_0 PFAM Heparinase II III-like protein - - - 0.00000000000000000000000000000000001363 155.0
HKD1_k127_6814050_0 Thioesterase domain - - - 5e-219 709.0
HKD1_k127_6814050_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 369.0
HKD1_k127_6814050_2 HAF family - - - 0.000008844 51.0
HKD1_k127_6820458_0 - - - - 9.735e-199 632.0
HKD1_k127_6820458_1 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 332.0
HKD1_k127_6834075_0 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 420.0
HKD1_k127_6834075_1 DinB superfamily K07552 - - 0.00000000000000000000000000000000009846 140.0
HKD1_k127_6834075_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000004912 129.0
HKD1_k127_6834075_3 TPR repeat - - - 0.0000000000000002775 91.0
HKD1_k127_6834075_4 Tetratricopeptide repeat protein - - - 0.000000000005564 75.0
HKD1_k127_6834075_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034 - 1.1.1.47 0.00004552 50.0
HKD1_k127_6843079_0 mannitol 2-dehydrogenase activity K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 564.0
HKD1_k127_6843079_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 376.0
HKD1_k127_6843079_2 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 259.0
HKD1_k127_6843079_3 TRAP transporter T-component - - - 0.000000000000000000000099 99.0
HKD1_k127_6845719_0 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001648 268.0
HKD1_k127_6848118_0 Belongs to the alpha-IPM synthase homocitrate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 305.0
HKD1_k127_6848118_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000009992 235.0
HKD1_k127_6862651_0 mannose metabolic process - - - 0.0 1131.0
HKD1_k127_6862651_1 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 492.0
HKD1_k127_6862651_2 Domain of unknown function (DUF4184) - - - 0.00000000000000000000000000000003991 137.0
HKD1_k127_6864506_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000004966 154.0
HKD1_k127_6864506_1 TPR repeat - - - 0.0000000000000000000000000000003818 135.0
HKD1_k127_6872401_1 F5/8 type C domain - - - 0.0002654 51.0
HKD1_k127_6878224_0 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 422.0
HKD1_k127_6878224_1 sugar phosphate isomerase - - - 0.0000000118 66.0
HKD1_k127_6881702_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001078 277.0
HKD1_k127_6881702_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001148 266.0
HKD1_k127_6881702_2 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000001375 180.0
HKD1_k127_6907679_0 RNA secondary structure unwinding K03724 - - 0.0 1418.0
HKD1_k127_6907679_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 339.0
HKD1_k127_6907679_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000471 206.0
HKD1_k127_6925089_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 520.0
HKD1_k127_6925089_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 511.0
HKD1_k127_6925089_10 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 290.0
HKD1_k127_6925089_11 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006321 289.0
HKD1_k127_6925089_12 Amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000513 267.0
HKD1_k127_6925089_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001687 240.0
HKD1_k127_6925089_14 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000003976 231.0
HKD1_k127_6925089_15 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000004426 215.0
HKD1_k127_6925089_16 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000005771 156.0
HKD1_k127_6925089_17 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.000000000000000000000000000000000006464 144.0
HKD1_k127_6925089_18 Polymer-forming cytoskeletal - - - 0.000000000000000000000000001098 119.0
HKD1_k127_6925089_19 - - - - 0.0000000000000000000000001051 116.0
HKD1_k127_6925089_2 Belongs to the GARS family K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 458.0
HKD1_k127_6925089_20 Prephenate dehydrogenase K00210 - 1.3.1.12 0.000000000000000000000001367 108.0
HKD1_k127_6925089_22 methyltransferase - - - 0.0000000000006775 77.0
HKD1_k127_6925089_3 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 441.0
HKD1_k127_6925089_4 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 404.0
HKD1_k127_6925089_5 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
HKD1_k127_6925089_6 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 383.0
HKD1_k127_6925089_7 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 365.0
HKD1_k127_6925089_8 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 383.0
HKD1_k127_6925089_9 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 352.0
HKD1_k127_6929115_0 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004509 284.0
HKD1_k127_6929115_1 Trehalose utilisation K09992 - - 0.0000000000000000000000003388 109.0
HKD1_k127_6929115_2 - - - - 0.00000006543 57.0
HKD1_k127_6951622_0 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 1.24e-204 654.0
HKD1_k127_6951622_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 479.0
HKD1_k127_6951622_2 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 432.0
HKD1_k127_6951622_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 358.0
HKD1_k127_6951622_4 Hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000004164 206.0
HKD1_k127_6955613_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 601.0
HKD1_k127_6955613_1 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 477.0
HKD1_k127_6955613_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00002119 49.0
HKD1_k127_6959964_0 PFAM oxidoreductase - - - 2.401e-202 637.0
HKD1_k127_6959964_1 ferredoxin-NADP+ reductase activity K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 408.0
HKD1_k127_6959964_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 297.0
HKD1_k127_6959964_3 COG3039 Transposase and inactivated derivatives, IS5 family K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000007302 252.0
HKD1_k127_6959964_4 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000002585 142.0
HKD1_k127_6959964_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000001311 87.0
HKD1_k127_6983211_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1294.0
HKD1_k127_6983211_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000005242 173.0
HKD1_k127_6983211_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000003769 114.0
HKD1_k127_6983211_3 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000001024 91.0
HKD1_k127_704223_0 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 443.0
HKD1_k127_704223_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000681 172.0
HKD1_k127_704223_2 dehalogenase' - - - 0.0000000000000000000000000000005545 135.0
HKD1_k127_7045548_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 480.0
HKD1_k127_7045548_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 452.0
HKD1_k127_7045548_2 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 324.0
HKD1_k127_7045548_3 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 290.0
HKD1_k127_7045548_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002878 141.0
HKD1_k127_7045548_5 Tetratricopeptide repeat - - - 0.000000000001011 78.0
HKD1_k127_706261_0 AcrB/AcrD/AcrF family K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 615.0
HKD1_k127_706261_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.000000000000000000000000000000000000000000000000006235 199.0
HKD1_k127_7078204_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.676e-211 671.0
HKD1_k127_7078204_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
HKD1_k127_7078204_2 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000000000003239 134.0
HKD1_k127_7078204_3 - - - - 0.0000000000000000000000000000008398 132.0
HKD1_k127_7078204_4 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000008827 111.0
HKD1_k127_7078204_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000411 99.0
HKD1_k127_7078204_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000006543 57.0
HKD1_k127_7079553_0 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 513.0
HKD1_k127_7079553_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 372.0
HKD1_k127_7079553_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 347.0
HKD1_k127_7079553_3 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000005128 139.0
HKD1_k127_7079553_4 Ribosomal L32p protein family K02911 - - 0.000000000000000000001409 94.0
HKD1_k127_7092600_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 309.0
HKD1_k127_7092600_1 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000000000001051 148.0
HKD1_k127_7092600_3 Cysteine-rich secretory protein family - - - 0.0000000000000005353 87.0
HKD1_k127_7092808_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 425.0
HKD1_k127_7092808_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 332.0
HKD1_k127_7092808_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001881 233.0
HKD1_k127_7092808_3 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000001432 205.0
HKD1_k127_7092808_4 GHKL domain - - - 0.00000000000000000000000000000000000003943 160.0
HKD1_k127_7092808_5 metabolite transporter - - - 0.000000000000000000000000004004 123.0
HKD1_k127_7099818_0 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009024 288.0
HKD1_k127_7099818_1 cAMP biosynthetic process - - - 0.00000000000000000000000000001108 123.0
HKD1_k127_7100461_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 9.075e-226 715.0
HKD1_k127_7100461_1 Aldehyde dehydrogenase family K00131 - 1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 562.0
HKD1_k127_7100461_2 dehydratase K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000172 254.0
HKD1_k127_7105290_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 362.0
HKD1_k127_7105290_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006281 265.0
HKD1_k127_7105290_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000228 203.0
HKD1_k127_7105290_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000007555 141.0
HKD1_k127_7111845_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 1.115e-273 850.0
HKD1_k127_7111845_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 541.0
HKD1_k127_7111845_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 417.0
HKD1_k127_7111845_3 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 377.0
HKD1_k127_7111845_4 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 292.0
HKD1_k127_7111845_5 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000001101 140.0
HKD1_k127_7111845_6 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000005115 106.0
HKD1_k127_7111845_7 Regulatory protein, FmdB family - - - 0.000000000002365 68.0
HKD1_k127_7132500_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 2.39e-233 731.0
HKD1_k127_7132500_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 380.0
HKD1_k127_7132500_10 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000002198 208.0
HKD1_k127_7132500_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000155 193.0
HKD1_k127_7132500_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000001182 190.0
HKD1_k127_7132500_13 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000001218 192.0
HKD1_k127_7132500_14 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000006023 197.0
HKD1_k127_7132500_15 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000003897 149.0
HKD1_k127_7132500_16 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.00000000000000000000000000000000002039 139.0
HKD1_k127_7132500_17 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000001031 145.0
HKD1_k127_7132500_18 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000006086 103.0
HKD1_k127_7132500_19 Protein of unknown function (DUF507) - - - 0.0000000000000006298 81.0
HKD1_k127_7132500_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
HKD1_k127_7132500_20 - - - - 0.000000000000001894 85.0
HKD1_k127_7132500_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 295.0
HKD1_k127_7132500_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 297.0
HKD1_k127_7132500_5 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001105 272.0
HKD1_k127_7132500_6 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000009605 246.0
HKD1_k127_7132500_7 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000001165 247.0
HKD1_k127_7132500_8 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000005271 241.0
HKD1_k127_7132500_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000002246 226.0
HKD1_k127_7140309_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1037.0
HKD1_k127_7140309_1 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 541.0
HKD1_k127_7140309_10 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000006792 97.0
HKD1_k127_7140309_2 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 357.0
HKD1_k127_7140309_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 331.0
HKD1_k127_7140309_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 295.0
HKD1_k127_7140309_5 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000003101 243.0
HKD1_k127_7140309_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000009775 220.0
HKD1_k127_7140309_7 response regulator - - - 0.00000000000000000000000000000000000001303 160.0
HKD1_k127_7140309_8 PFAM microcompartments protein K04027 - - 0.0000000000000000000000000000000000579 137.0
HKD1_k127_7140309_9 PASTA domain K12132 - 2.7.11.1 0.0000000000000000000000000000001156 133.0
HKD1_k127_7150954_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 333.0
HKD1_k127_7162196_0 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000295 278.0
HKD1_k127_7162196_1 protein kinase activity K06915 - - 0.0000000000000000000000001313 108.0
HKD1_k127_7164333_0 threonine synthase activity K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 572.0
HKD1_k127_7164333_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 454.0
HKD1_k127_7164333_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 418.0
HKD1_k127_7164333_3 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 379.0
HKD1_k127_7164333_4 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
HKD1_k127_7164333_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 303.0
HKD1_k127_7164333_6 ThiS family K03636 - - 0.00000000000000000000000000008382 118.0
HKD1_k127_7164333_7 Protein of unknown function (DUF971) - - - 0.00000000000000000000000009614 109.0
HKD1_k127_7164333_8 COG1387 Histidinol phosphatase and related hydrolases of the PHP family K04486 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 0.000000000000000000509 88.0
HKD1_k127_7164333_9 - - - - 0.0008835 45.0
HKD1_k127_7175321_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.625e-215 688.0
HKD1_k127_7175321_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 373.0
HKD1_k127_7175321_10 Protein of unknown function (DUF3108) - - - 0.000000000000001038 87.0
HKD1_k127_7175321_2 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 362.0
HKD1_k127_7175321_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 317.0
HKD1_k127_7175321_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 322.0
HKD1_k127_7175321_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000002224 244.0
HKD1_k127_7175321_6 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000002337 185.0
HKD1_k127_7175321_7 methyltransferase - - - 0.000000000000000000000000000000000003427 147.0
HKD1_k127_7175321_8 Methyltransferase domain - - - 0.0000000000000000000000000007499 123.0
HKD1_k127_7175321_9 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000000002337 111.0
HKD1_k127_7175587_0 Sulfatase - - - 1.246e-242 756.0
HKD1_k127_7175587_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000001891 173.0
HKD1_k127_7175587_2 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000000001535 146.0
HKD1_k127_7175587_3 Periplasmic or secreted lipoprotein - - - 0.0000000000000000002864 96.0
HKD1_k127_7181303_0 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 314.0
HKD1_k127_7181303_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
HKD1_k127_7181303_2 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000001193 222.0
HKD1_k127_7181303_3 Prephenate dehydrogenase K00210 - 1.3.1.12 0.00000000000000000000000000000000003556 139.0
HKD1_k127_7181303_4 Peptidase M16 - - - 0.000000000000000000000000000000145 141.0
HKD1_k127_7181303_5 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000006122 126.0
HKD1_k127_7181303_6 oxidoreductase activity K12511 - - 0.00011 53.0
HKD1_k127_7181303_7 Tetratricopeptide repeats - - - 0.0004889 52.0
HKD1_k127_7181303_8 Bardet-Biedl syndrome 4 K16531 GO:0000003,GO:0000226,GO:0000242,GO:0000278,GO:0000281,GO:0000910,GO:0001085,GO:0001103,GO:0001654,GO:0001750,GO:0001754,GO:0001764,GO:0001838,GO:0001841,GO:0001843,GO:0001894,GO:0001895,GO:0001917,GO:0001947,GO:0002009,GO:0003006,GO:0003007,GO:0003008,GO:0003013,GO:0003073,GO:0003085,GO:0003143,GO:0003352,GO:0003356,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0006810,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007368,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007507,GO:0007600,GO:0007606,GO:0007608,GO:0007610,GO:0008015,GO:0008064,GO:0008092,GO:0008104,GO:0008134,GO:0008150,GO:0008217,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010468,GO:0010564,GO:0010605,GO:0010629,GO:0010638,GO:0010639,GO:0014020,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016331,GO:0016358,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019216,GO:0019221,GO:0019222,GO:0019953,GO:0021537,GO:0021543,GO:0021544,GO:0021591,GO:0021756,GO:0021761,GO:0021766,GO:0021915,GO:0021987,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030154,GO:0030182,GO:0030534,GO:0030832,GO:0030833,GO:0030837,GO:0030900,GO:0031023,GO:0031090,GO:0031175,GO:0031253,GO:0031333,GO:0031344,GO:0031346,GO:0031514,GO:0031667,GO:0032095,GO:0032096,GO:0032098,GO:0032099,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032231,GO:0032271,GO:0032272,GO:0032391,GO:0032400,GO:0032401,GO:0032402,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032535,GO:0032870,GO:0032879,GO:0032886,GO:0032956,GO:0032970,GO:0032991,GO:0033036,GO:0033043,GO:0033059,GO:0033210,GO:0033365,GO:0034097,GO:0034260,GO:0034451,GO:0034452,GO:0034453,GO:0034454,GO:0034464,GO:0034504,GO:0034613,GO:0035050,GO:0035148,GO:0035176,GO:0035239,GO:0035295,GO:0035845,GO:0035869,GO:0036064,GO:0038108,GO:0040008,GO:0040011,GO:0040012,GO:0040014,GO:0040018,GO:0042221,GO:0042461,GO:0042462,GO:0042592,GO:0042995,GO:0043005,GO:0043009,GO:0043014,GO:0043086,GO:0043087,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043473,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044320,GO:0044321,GO:0044380,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044450,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044782,GO:0045185,GO:0045444,GO:0045494,GO:0045724,GO:0045776,GO:0045927,GO:0046530,GO:0046548,GO:0046907,GO:0048232,GO:0048468,GO:0048487,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048583,GO:0048585,GO:0048592,GO:0048598,GO:0048609,GO:0048638,GO:0048639,GO:0048646,GO:0048666,GO:0048699,GO:0048729,GO:0048731,GO:0048854,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050893,GO:0050896,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051179,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051270,GO:0051301,GO:0051302,GO:0051336,GO:0051346,GO:0051457,GO:0051492,GO:0051493,GO:0051494,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051651,GO:0051656,GO:0051674,GO:0051703,GO:0051704,GO:0051705,GO:0051716,GO:0051726,GO:0051875,GO:0051904,GO:0051905,GO:0060170,GO:0060249,GO:0060255,GO:0060271,GO:0060295,GO:0060296,GO:0060322,GO:0060324,GO:0060429,GO:0060491,GO:0060562,GO:0060606,GO:0060612,GO:0060613,GO:0060632,GO:0061371,GO:0061448,GO:0061512,GO:0061640,GO:0065007,GO:0065008,GO:0065009,GO:0070491,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071345,GO:0071495,GO:0071539,GO:0071840,GO:0071944,GO:0072175,GO:0072359,GO:0072393,GO:0072595,GO:0072698,GO:0080090,GO:0090066,GO:0090596,GO:0097458,GO:0097499,GO:0097730,GO:0097731,GO:0097733,GO:0098588,GO:0098590,GO:0110020,GO:0110053,GO:0120025,GO:0120031,GO:0120032,GO:0120034,GO:0120035,GO:0120036,GO:0120038,GO:1902017,GO:1902019,GO:1902115,GO:1902117,GO:1902855,GO:1902903,GO:1902904,GO:1903047,GO:1903546,GO:1905508,GO:1905515,GO:2000145 - 0.0005024 51.0
HKD1_k127_7183613_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 1.14e-322 1014.0
HKD1_k127_7183613_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000009201 78.0
HKD1_k127_7183613_2 Aldo Keto reductase K05882 - 1.1.1.91 0.00000000000745 66.0
HKD1_k127_7188070_0 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 465.0
HKD1_k127_7188070_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 425.0
HKD1_k127_7188070_2 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000001224 175.0
HKD1_k127_7188070_3 identical protein binding K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.00000000000000000000000009661 114.0
HKD1_k127_7188070_4 identical protein binding K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.000000000000007394 83.0
HKD1_k127_7188070_5 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0003393 50.0
HKD1_k127_71926_0 radical SAM domain protein - - - 8.049e-289 897.0
HKD1_k127_71926_1 GTP-binding protein TypA K06207 - - 3.88e-258 808.0
HKD1_k127_71926_10 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000000000000000000000000002109 215.0
HKD1_k127_71926_11 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000006068 192.0
HKD1_k127_71926_12 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000006573 194.0
HKD1_k127_71926_13 Phospholipid N-methyltransferase - - - 0.0000000000000000000000000000000000000003004 158.0
HKD1_k127_71926_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000002144 135.0
HKD1_k127_71926_15 oxidoreductase activity - - - 0.0001017 54.0
HKD1_k127_71926_16 30S ribosomal protein Thx K19033 - - 0.0003166 44.0
HKD1_k127_71926_2 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 543.0
HKD1_k127_71926_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 390.0
HKD1_k127_71926_4 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 376.0
HKD1_k127_71926_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 362.0
HKD1_k127_71926_6 Glyoxalase-like domain K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002061 258.0
HKD1_k127_71926_7 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000004164 265.0
HKD1_k127_71926_8 allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008437 265.0
HKD1_k127_71926_9 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001291 253.0
HKD1_k127_7200024_0 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 458.0
HKD1_k127_7200024_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
HKD1_k127_7200024_2 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004322 234.0
HKD1_k127_7200024_3 PFAM lipopolysaccharide biosynthesis K08252,K16554 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000003296 224.0
HKD1_k127_7242630_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 453.0
HKD1_k127_7242630_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 446.0
HKD1_k127_7242630_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 290.0
HKD1_k127_7242630_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000003532 157.0
HKD1_k127_7242630_4 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000068 122.0
HKD1_k127_7242630_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000001326 123.0
HKD1_k127_7242630_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000002748 89.0
HKD1_k127_7252876_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 347.0
HKD1_k127_7252876_1 PFAM PKD domain - - - 0.000000000000000000000000000000000000000000555 180.0
HKD1_k127_7252876_2 - - - - 0.00000001376 66.0
HKD1_k127_7280476_0 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004895 278.0
HKD1_k127_7280476_1 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.0000000000000000000000000000000000000000000000000000000000001162 214.0
HKD1_k127_7280476_2 Cupin - - - 0.00000001255 63.0
HKD1_k127_7283660_0 silver ion transport K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 357.0
HKD1_k127_7283660_1 Protein of unknown function (DUF1232) - - - 0.0000000000000001041 86.0
HKD1_k127_729398_1 3-keto-5-aminohexanoate cleavage protein K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 347.0
HKD1_k127_729398_2 Alpha amylase catalytic - - - 0.00000000000000000000000000000000000000000000000000586 205.0
HKD1_k127_729398_3 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000002862 183.0
HKD1_k127_729398_4 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000002193 181.0
HKD1_k127_729398_6 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000009911 87.0
HKD1_k127_729398_7 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.00000000000002125 85.0
HKD1_k127_729398_8 AntiSigma factor - - - 0.00000001073 60.0
HKD1_k127_7294163_0 ABC-2 family transporter protein - - - 7.377e-232 740.0
HKD1_k127_7294163_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 427.0
HKD1_k127_7294163_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 419.0
HKD1_k127_7294163_3 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 425.0
HKD1_k127_7294163_4 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 304.0
HKD1_k127_7294163_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 309.0
HKD1_k127_7294163_6 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000003279 229.0
HKD1_k127_7294163_7 lytic transglycosylase activity K03194 - - 0.0000000000000000001007 103.0
HKD1_k127_7294163_8 sulfuric ester hydrolase activity - - - 0.000002022 61.0
HKD1_k127_7301414_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.645e-288 906.0
HKD1_k127_7301414_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 2.687e-206 652.0
HKD1_k127_7301414_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003145 243.0
HKD1_k127_7301414_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000004579 226.0
HKD1_k127_7301414_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000001749 171.0
HKD1_k127_7301414_5 Methyltransferase - - - 0.00000000000000000000000000000000000002384 149.0
HKD1_k127_7301414_6 - - - - 0.00000000000000000000004566 106.0
HKD1_k127_7301414_7 Hsp20/alpha crystallin family K13993 - - 0.000000000000000003167 90.0
HKD1_k127_7301414_8 Putative zinc-finger - - - 0.00000000002317 72.0
HKD1_k127_7301414_9 Putative adhesin - - - 0.000002674 58.0
HKD1_k127_7316031_0 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 591.0
HKD1_k127_7316031_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 477.0
HKD1_k127_7316031_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.000000000000000000001061 98.0
HKD1_k127_73271_0 Beta-L-arabinofuranosidase, GH127 - - - 1.76e-246 778.0
HKD1_k127_73271_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 8.153e-246 769.0
HKD1_k127_73271_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 5.834e-224 710.0
HKD1_k127_73271_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 484.0
HKD1_k127_73271_4 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 456.0
HKD1_k127_73271_5 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 411.0
HKD1_k127_73271_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000001377 138.0
HKD1_k127_73271_7 Molybdopterin oxidoreductase - - - 0.00000000000000000000000000000007629 127.0
HKD1_k127_73271_8 Transposase IS200 like - - - 0.000000000000000000000001331 107.0
HKD1_k127_7333576_0 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 338.0
HKD1_k127_7333576_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000002045 201.0
HKD1_k127_7333576_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000003875 212.0
HKD1_k127_7333576_3 spermidine synthase activity - - - 0.000000000000004247 82.0
HKD1_k127_7336875_0 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003558 209.0
HKD1_k127_7336875_1 Peptidase family M23 - - - 0.00000000000000000000000000000001656 132.0
HKD1_k127_7336875_2 Zinc-binding dehydrogenase - - - 0.000000000000000000001925 96.0
HKD1_k127_7336875_3 Acyl carrier protein phosphodiesterase - - - 0.00000001747 56.0
HKD1_k127_7336875_4 - - - - 0.000005234 54.0
HKD1_k127_7337478_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 3.984e-240 752.0
HKD1_k127_7337478_1 NAD binding K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 522.0
HKD1_k127_7337478_10 NADH dehydrogenase (ubiquinone) activity K00330,K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000001378 147.0
HKD1_k127_7337478_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000002123 146.0
HKD1_k127_7337478_12 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.000000000000000000000000000002953 123.0
HKD1_k127_7337478_13 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000002722 108.0
HKD1_k127_7337478_14 Putative peptidoglycan binding domain - - - 0.000000006287 63.0
HKD1_k127_7337478_16 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.0009163 43.0
HKD1_k127_7337478_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 487.0
HKD1_k127_7337478_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 425.0
HKD1_k127_7337478_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 399.0
HKD1_k127_7337478_5 ATP synthesis coupled electron transport K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 382.0
HKD1_k127_7337478_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003523 283.0
HKD1_k127_7337478_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002456 255.0
HKD1_k127_7337478_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000007182 171.0
HKD1_k127_7337478_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000001318 161.0
HKD1_k127_7346945_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 488.0
HKD1_k127_7346945_1 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 421.0
HKD1_k127_7346945_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000003847 207.0
HKD1_k127_7346945_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000008585 54.0
HKD1_k127_7355169_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 457.0
HKD1_k127_7355169_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000001541 216.0
HKD1_k127_7363848_0 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000007445 129.0
HKD1_k127_7363848_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000001535 143.0
HKD1_k127_7363848_2 WD40 domain protein beta Propeller - - - 0.000004629 49.0
HKD1_k127_7370279_0 mannose metabolic process - - - 0.0 1083.0
HKD1_k127_7370279_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 376.0
HKD1_k127_7373242_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 402.0
HKD1_k127_7373242_1 amidohydrolase K07045 - - 0.0000000000000000001704 102.0
HKD1_k127_7373242_2 transposition K07497 - - 0.0000000000000000005554 94.0
HKD1_k127_7373242_3 - - - - 0.000007433 56.0
HKD1_k127_7383411_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 419.0
HKD1_k127_7383411_1 ribulose-bisphosphate carboxylase activity K01601 - 4.1.1.39 0.00000000004075 66.0
HKD1_k127_7402629_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 399.0
HKD1_k127_7402629_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000202 266.0
HKD1_k127_7402629_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000005118 169.0
HKD1_k127_7402629_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000001685 146.0
HKD1_k127_7402629_4 Domain of unknown function (DUF309) K09763 - - 0.00000000000004362 79.0
HKD1_k127_7402629_5 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000001422 61.0
HKD1_k127_7417978_0 Peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 475.0
HKD1_k127_7417978_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 322.0
HKD1_k127_7417978_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000007076 168.0
HKD1_k127_7417978_3 Smr domain - - - 0.000000000000000000000000000003318 128.0
HKD1_k127_7417978_4 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000001753 66.0
HKD1_k127_742683_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 7.732e-252 800.0
HKD1_k127_742683_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 321.0
HKD1_k127_7452490_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 344.0
HKD1_k127_7452490_1 - - - - 0.000000000000001277 81.0
HKD1_k127_7452490_2 PFAM chemotaxis K03406,K07216 - - 0.0000000000000257 79.0
HKD1_k127_7472200_0 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 589.0
HKD1_k127_7472200_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 367.0
HKD1_k127_7472200_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000001261 212.0
HKD1_k127_7472200_3 polysaccharide deacetylase - - - 0.00000000000000000000007814 115.0
HKD1_k127_7472200_4 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000001477 81.0
HKD1_k127_7472200_5 Glycosyl transferases group 1 - - - 0.00000000000001547 83.0
HKD1_k127_7472200_6 FemAB family - - - 0.000000000007323 76.0
HKD1_k127_7483414_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 472.0
HKD1_k127_7483414_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000003879 206.0
HKD1_k127_7483414_2 chain release factor K15034 - - 0.0000000000000000000000000000000001554 137.0
HKD1_k127_7483414_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000001438 123.0
HKD1_k127_7492975_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 436.0
HKD1_k127_7492975_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 362.0
HKD1_k127_7509032_0 TLC ATP/ADP transporter K03301 - - 0.000000000000000000000000000004645 135.0
HKD1_k127_7509126_0 Phosphate acetyl/butaryl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 296.0
HKD1_k127_7509126_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 288.0
HKD1_k127_7509126_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 0.00006763 47.0
HKD1_k127_7535636_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 434.0
HKD1_k127_7535636_1 PFAM Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000000000009206 126.0
HKD1_k127_7535636_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000001362 64.0
HKD1_k127_7546062_0 transmembrane transporter activity K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 352.0
HKD1_k127_7546062_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 336.0
HKD1_k127_7546062_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000002797 213.0
HKD1_k127_7546671_0 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 290.0
HKD1_k127_7546671_1 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001764 282.0
HKD1_k127_7546671_2 translation initiation factor activity K06370 - - 0.00000000000000000000000000000000000000000000000000000000000000005544 247.0
HKD1_k127_7546671_3 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000004226 192.0
HKD1_k127_7546671_4 Pfam:GBA2_N K17108 - 3.2.1.45 0.00000000000000000000001353 118.0
HKD1_k127_759175_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 521.0
HKD1_k127_759175_1 FGGY family of carbohydrate kinases, N-terminal domain K11214 - 2.7.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 300.0
HKD1_k127_759175_2 - - - - 0.0000000000000009286 83.0
HKD1_k127_759175_3 protein kinase activity K12132 - 2.7.11.1 0.00000294 52.0
HKD1_k127_7594413_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000000001172 220.0
HKD1_k127_7594413_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000003013 220.0
HKD1_k127_7594413_3 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000004591 89.0
HKD1_k127_7595167_0 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 460.0
HKD1_k127_7595167_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 372.0
HKD1_k127_7595167_2 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 289.0
HKD1_k127_7595167_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004463 258.0
HKD1_k127_7595167_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000001382 197.0
HKD1_k127_7595167_5 - - - - 0.00000000001866 77.0
HKD1_k127_7596672_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 541.0
HKD1_k127_7596672_1 ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 400.0
HKD1_k127_7596672_2 CDP-alcohol phosphatidyltransferase - - - 0.0000000000005755 71.0
HKD1_k127_7599632_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 585.0
HKD1_k127_7599632_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 319.0
HKD1_k127_7599632_2 Transposase - - - 0.00000000000000001078 89.0
HKD1_k127_7599632_3 DDE superfamily endonuclease K07494 - - 0.00000000000002143 80.0
HKD1_k127_7603042_0 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002342 280.0
HKD1_k127_7603042_1 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000003061 187.0
HKD1_k127_7603042_2 methyltransferase - - - 0.000000000000000000000000002515 125.0
HKD1_k127_7603042_3 protein conserved in bacteria - - - 0.000000000000000002198 85.0
HKD1_k127_761580_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 479.0
HKD1_k127_761580_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 306.0
HKD1_k127_761580_2 - - - - 0.000000000000000000000000000000000000000005131 158.0
HKD1_k127_761580_3 - - - - 0.00000000000000000000000001012 124.0
HKD1_k127_761580_4 Methionine biosynthesis protein MetW - - - 0.0000000000000001693 90.0
HKD1_k127_761580_5 - - - - 0.00000005856 57.0
HKD1_k127_7626008_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 343.0
HKD1_k127_7626008_1 Transposase K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 329.0
HKD1_k127_7626008_2 acetyltransferase - - - 0.000001239 52.0
HKD1_k127_762757_0 mannose metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 443.0
HKD1_k127_762757_1 Transcriptional regulator - - - 0.00000000000000000003218 94.0
HKD1_k127_762757_2 PFAM HWE histidine kinase - - - 0.0002234 50.0
HKD1_k127_7629981_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 4.175e-218 705.0
HKD1_k127_7629981_1 PFAM FAD linked oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 418.0
HKD1_k127_7629981_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 292.0
HKD1_k127_7631792_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1215.0
HKD1_k127_7631792_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.315e-257 805.0
HKD1_k127_7631792_2 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 340.0
HKD1_k127_7631792_3 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000741 208.0
HKD1_k127_7631792_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000003619 203.0
HKD1_k127_7631792_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000001345 181.0
HKD1_k127_7650866_0 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 472.0
HKD1_k127_7650866_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 443.0
HKD1_k127_7650866_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000003848 183.0
HKD1_k127_7650866_3 oxidoreductase activity K12511 - - 0.0000000000000000007471 98.0
HKD1_k127_7650944_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 511.0
HKD1_k127_7650944_1 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 408.0
HKD1_k127_7650944_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000001413 180.0
HKD1_k127_7650944_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000001213 167.0
HKD1_k127_7650944_4 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000003964 153.0
HKD1_k127_7650944_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000006183 122.0
HKD1_k127_7650944_6 - - - - 0.00000000000000000000004247 108.0
HKD1_k127_7650944_7 Dienelactone hydrolase family - - - 0.00000000000000209 87.0
HKD1_k127_7650944_8 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000002539 87.0
HKD1_k127_7650944_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000002096 70.0
HKD1_k127_7659704_0 Protein of unknown function (DUF1553) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 645.0
HKD1_k127_7659704_1 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000000000009319 131.0
HKD1_k127_7667336_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 565.0
HKD1_k127_7667336_1 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 503.0
HKD1_k127_7667336_2 Pfam Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 339.0
HKD1_k127_7667336_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001415 270.0
HKD1_k127_7667336_4 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000009614 181.0
HKD1_k127_7667336_5 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000001367 136.0
HKD1_k127_7667336_6 Glycosyl hydrolases family 38 N-terminal domain - - - 0.0000000000000000000000002256 115.0
HKD1_k127_7694215_0 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000001582 227.0
HKD1_k127_7694215_1 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000000000000000000001281 231.0
HKD1_k127_7694215_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000002054 143.0
HKD1_k127_7694215_3 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000001593 104.0
HKD1_k127_7694215_4 Subtilase family - - - 0.0000000000000002768 93.0
HKD1_k127_7694559_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 443.0
HKD1_k127_7694559_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 376.0
HKD1_k127_7694559_2 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 314.0
HKD1_k127_7694559_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002233 252.0
HKD1_k127_7694559_4 Capsule assembly protein Wzi - - - 0.000000000000000000000000000002466 130.0
HKD1_k127_7694559_5 Putative phosphatase (DUF442) - - - 0.000000000000000007265 86.0
HKD1_k127_7694559_6 diguanylate cyclase - - - 0.000000005151 69.0
HKD1_k127_7696274_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 587.0
HKD1_k127_7696274_2 mechanosensitive ion channel - - - 0.00000000000002635 82.0
HKD1_k127_7699525_0 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 464.0
HKD1_k127_7699525_1 protein histidine kinase activity K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 430.0
HKD1_k127_7702665_0 Alpha beta hydrolase fold-3 domain protein - - - 5.208e-202 643.0
HKD1_k127_7702665_1 spore germination - - - 0.00000000000000000000000000000000000000000000000000000001312 208.0
HKD1_k127_7702665_2 Sugar (and other) transporter K08369 - - 0.000000000000000000000000000000000000000000003853 170.0
HKD1_k127_7702665_3 Sugar (and other) transporter K08369 - - 0.0000000000000001391 80.0
HKD1_k127_7704473_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004195 267.0
HKD1_k127_7712664_0 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 330.0
HKD1_k127_7712664_1 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000008928 203.0
HKD1_k127_7712664_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000003251 68.0
HKD1_k127_7712664_3 Sporulation related domain - - - 0.0003474 51.0
HKD1_k127_7715731_0 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 504.0
HKD1_k127_7715731_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 370.0
HKD1_k127_7715731_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 366.0
HKD1_k127_7715731_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 349.0
HKD1_k127_7715731_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 321.0
HKD1_k127_7715731_5 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
HKD1_k127_7715731_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002034 280.0
HKD1_k127_7715731_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002883 285.0
HKD1_k127_7715731_8 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000004306 229.0
HKD1_k127_7715731_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000807 79.0
HKD1_k127_7738656_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.801e-194 616.0
HKD1_k127_7738656_1 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 458.0
HKD1_k127_7738656_2 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000134 152.0
HKD1_k127_7754984_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 530.0
HKD1_k127_7754984_1 nuclease of the RecB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 426.0
HKD1_k127_7754984_2 - - - - 0.000000000000000000000000000000000006352 140.0
HKD1_k127_7754984_3 Domain of unknown function (DUF4437) - - - 0.00000000002551 68.0
HKD1_k127_775645_0 Heat shock 70 kDa protein K04043 - - 1.475e-233 738.0
HKD1_k127_775645_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006041 259.0
HKD1_k127_775645_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000001208 162.0
HKD1_k127_775645_3 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000004359 139.0
HKD1_k127_775645_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000006244 135.0
HKD1_k127_7760678_0 PFAM NHL repeat containing protein - - - 0.0 1401.0
HKD1_k127_7760678_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 362.0
HKD1_k127_7760678_2 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002405 216.0
HKD1_k127_7760678_3 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000003531 134.0
HKD1_k127_7760678_4 CAAX protease self-immunity K07052 - - 0.0000000000000000003677 97.0
HKD1_k127_7770084_0 Ftsk_gamma K03466 - - 4.123e-225 722.0
HKD1_k127_7770084_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 614.0
HKD1_k127_7770084_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 500.0
HKD1_k127_7770084_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 491.0
HKD1_k127_7770084_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000108 254.0
HKD1_k127_7770084_5 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000001769 214.0
HKD1_k127_7770084_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000001035 184.0
HKD1_k127_7770084_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000007334 172.0
HKD1_k127_7770084_8 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000004064 140.0
HKD1_k127_7770084_9 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000001307 124.0
HKD1_k127_7780049_0 AAA domain - - - 1.78e-218 703.0
HKD1_k127_7780049_1 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 6.93e-196 634.0
HKD1_k127_7780049_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 481.0
HKD1_k127_7780049_3 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000002238 238.0
HKD1_k127_7786155_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 516.0
HKD1_k127_7786155_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 296.0
HKD1_k127_7786155_2 peptidyl-tyrosine sulfation - - - 0.000000000000001465 90.0
HKD1_k127_7786155_3 - - - - 0.0000007732 52.0
HKD1_k127_7788115_0 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 413.0
HKD1_k127_7788115_1 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000005379 245.0
HKD1_k127_7788115_2 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000232 168.0
HKD1_k127_7788115_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000008216 73.0
HKD1_k127_7788115_4 response regulator receiver - - - 0.00003055 53.0
HKD1_k127_779833_0 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 498.0
HKD1_k127_779833_1 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 465.0
HKD1_k127_779833_2 - - - - 0.00000000000002492 81.0
HKD1_k127_7800899_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 418.0
HKD1_k127_7800899_1 - - - - 0.00000000000000000000000000002173 133.0
HKD1_k127_7811968_0 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000004198 187.0
HKD1_k127_7811968_1 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000002074 173.0
HKD1_k127_7811968_2 PFAM histidine kinase, HAMP region domain protein - - - 0.0000000000000000000000000002428 121.0
HKD1_k127_7811968_3 - - - - 0.0000000000000000000002039 103.0
HKD1_k127_7814573_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 614.0
HKD1_k127_7814573_1 all-trans-retinol 13,14-reductase activity K09516 - 1.3.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 584.0
HKD1_k127_7814573_2 PFAM alpha amylase, catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 432.0
HKD1_k127_7814573_3 beta-glucosidase activity K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000002339 265.0
HKD1_k127_7814573_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000008132 222.0
HKD1_k127_7815216_0 COG0534 Na -driven multidrug efflux pump K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 489.0
HKD1_k127_7815216_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 382.0
HKD1_k127_7815216_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 301.0
HKD1_k127_7815216_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000002958 108.0
HKD1_k127_7815216_4 Phosphate acyltransferases - - - 0.0000000000000000000000007858 108.0
HKD1_k127_7815567_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1215.0
HKD1_k127_7815567_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 1.325e-216 684.0
HKD1_k127_7815567_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000002516 100.0
HKD1_k127_7815567_2 Phospholipase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 577.0
HKD1_k127_7815567_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 411.0
HKD1_k127_7815567_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 344.0
HKD1_k127_7815567_5 Peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 342.0
HKD1_k127_7815567_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000006128 228.0
HKD1_k127_7815567_7 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000008138 196.0
HKD1_k127_7815567_8 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000008047 156.0
HKD1_k127_7815567_9 Stage II sporulation protein K06381 - - 0.00000000000000000000000005879 121.0
HKD1_k127_7820824_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 512.0
HKD1_k127_7820824_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 388.0
HKD1_k127_7820824_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.00000000000000005249 82.0
HKD1_k127_7820824_2 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 377.0
HKD1_k127_7820824_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 368.0
HKD1_k127_7820824_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 364.0
HKD1_k127_7820824_5 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 347.0
HKD1_k127_7820824_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000001134 181.0
HKD1_k127_7820824_7 NUDIX domain - - - 0.0000000000000000000000000000000000002309 149.0
HKD1_k127_7820824_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000009205 117.0
HKD1_k127_7820824_9 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000005466 117.0
HKD1_k127_7830771_0 Transposase IS200 like K07491 - - 0.00000000000000000003304 91.0
HKD1_k127_7830771_1 viral genome integration into host DNA K04763 - - 0.00000009259 56.0
HKD1_k127_7830771_2 PFAM NHL repeat containing protein K13735 - - 0.0008998 52.0
HKD1_k127_7846996_0 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000001068 196.0
HKD1_k127_7846996_1 - - - - 0.0000000001282 75.0
HKD1_k127_78535_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 344.0
HKD1_k127_78535_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000003972 118.0
HKD1_k127_78582_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.674e-250 785.0
HKD1_k127_78582_1 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 397.0
HKD1_k127_78582_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000187 137.0
HKD1_k127_7860553_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 490.0
HKD1_k127_7860553_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 318.0
HKD1_k127_7860553_2 Belongs to the ompA family - - - 0.0001194 53.0
HKD1_k127_786113_0 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 377.0
HKD1_k127_786113_1 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000002456 66.0
HKD1_k127_7861411_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000005207 184.0
HKD1_k127_7861411_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000006602 140.0
HKD1_k127_7879513_1 polysaccharide lyase family 8 domain protein K01727 GO:0005575,GO:0005576 4.2.2.1 0.00001351 55.0
HKD1_k127_7891669_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 387.0
HKD1_k127_7891669_1 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 357.0
HKD1_k127_7891669_2 Integrase core domain - - - 0.0000000000000000000000000001438 118.0
HKD1_k127_7891669_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000004232 123.0
HKD1_k127_7891669_4 ATPases associated with a variety of cellular activities K01990 - - 0.0001847 45.0
HKD1_k127_7899503_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002021 287.0
HKD1_k127_7899503_1 Putative RNA methylase family UPF0020 - - - 0.0000000000001915 79.0
HKD1_k127_7899503_2 Cupin 2, conserved barrel domain protein - - - 0.0000000001984 67.0
HKD1_k127_7899503_3 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000002403 67.0
HKD1_k127_7899503_4 ubiE/COQ5 methyltransferase family - - - 0.0000000005405 62.0
HKD1_k127_7904148_0 Beta-lactamase - - - 6.424e-199 631.0
HKD1_k127_7904148_1 UPF0314 protein - - - 0.000000000000000000000000000000000000000000000002402 180.0
HKD1_k127_7904148_2 membrane - - - 0.000004044 51.0
HKD1_k127_7949313_0 Aminotransferase, class I K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 570.0
HKD1_k127_7949313_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 313.0
HKD1_k127_7949313_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.00002197 50.0
HKD1_k127_7951742_0 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 511.0
HKD1_k127_7951742_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000001784 258.0
HKD1_k127_7951742_2 outer membrane autotransporter barrel domain protein - - - 0.0006667 44.0
HKD1_k127_7969832_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.293e-276 860.0
HKD1_k127_7969832_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 608.0
HKD1_k127_7969832_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 449.0
HKD1_k127_7969832_3 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 423.0
HKD1_k127_7969832_4 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 420.0
HKD1_k127_7973143_0 beta-galactosidase activity - - - 4.547e-199 640.0
HKD1_k127_7973143_1 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.00000000000000000000000000000000000000000000000000000003511 209.0
HKD1_k127_7984272_0 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000001685 214.0
HKD1_k127_7984272_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000001249 219.0
HKD1_k127_7984272_2 rhs family - - - 0.000000000000006347 89.0
HKD1_k127_8003297_0 Amino acid adenylation domain - - - 0.0000000000000000000000000004069 116.0
HKD1_k127_8003297_1 nuclear chromosome segregation - - - 0.00000000000000000000007804 113.0
HKD1_k127_8021314_0 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 445.0
HKD1_k127_8021314_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 314.0
HKD1_k127_8030753_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.831e-226 713.0
HKD1_k127_8030753_1 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 479.0
HKD1_k127_8030753_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 402.0
HKD1_k127_8030753_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000459 191.0
HKD1_k127_8030753_4 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000003824 131.0
HKD1_k127_804806_0 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000003447 201.0
HKD1_k127_804806_1 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000001491 103.0
HKD1_k127_804806_2 Membrane-bound dehydrogenase domain K09992 - - 0.0008363 50.0
HKD1_k127_815198_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 314.0
HKD1_k127_815198_1 Polysaccharide lyase family 4, domain III - - - 0.00000000000000000000000000000000006985 142.0
HKD1_k127_826326_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000161 68.0
HKD1_k127_826326_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000005439 59.0
HKD1_k127_827776_0 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 555.0
HKD1_k127_827776_1 Enolase C-terminal domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 532.0
HKD1_k127_827776_10 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000009446 224.0
HKD1_k127_827776_11 lipopolysaccharide transport K09774 - - 0.000000000000000000000000000000000000000000000000000000203 219.0
HKD1_k127_827776_12 Thioredoxin-like - - - 0.0000000000000000000000000000000000001126 148.0
HKD1_k127_827776_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000001353 142.0
HKD1_k127_827776_14 Tetratricopeptide repeat - - - 0.00000000000000000003606 92.0
HKD1_k127_827776_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 497.0
HKD1_k127_827776_3 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 394.0
HKD1_k127_827776_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
HKD1_k127_827776_5 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 339.0
HKD1_k127_827776_6 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 327.0
HKD1_k127_827776_7 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 329.0
HKD1_k127_827776_8 COG1230 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008306 259.0
HKD1_k127_827776_9 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
HKD1_k127_836725_0 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001056 284.0
HKD1_k127_836725_1 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000000000002191 201.0
HKD1_k127_836725_2 Transposase - - - 0.00000000000000000000000000004659 119.0
HKD1_k127_836725_3 Cro/C1-type HTH DNA-binding domain - - - 0.00003115 53.0
HKD1_k127_85513_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.134e-262 818.0
HKD1_k127_85513_1 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 354.0
HKD1_k127_85513_10 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.00000000000000000000000000000000000004216 160.0
HKD1_k127_85513_2 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 332.0
HKD1_k127_85513_3 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 294.0
HKD1_k127_85513_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007897 286.0
HKD1_k127_85513_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000001143 268.0
HKD1_k127_85513_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002472 277.0
HKD1_k127_85513_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
HKD1_k127_85513_8 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000002877 187.0
HKD1_k127_85513_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000001437 163.0
HKD1_k127_856251_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007514 274.0
HKD1_k127_856251_1 - - - - 0.0000000000000000000005272 102.0
HKD1_k127_856251_2 leucine-zipper of insertion element IS481 K07497 - - 0.000000000000000000005169 93.0
HKD1_k127_856251_3 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000005501 85.0
HKD1_k127_856251_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000005627 69.0
HKD1_k127_856251_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000003237 66.0
HKD1_k127_856251_6 - - - - 0.0000000006524 66.0
HKD1_k127_856251_7 InterPro IPR007367 - - - 0.00000000466 61.0
HKD1_k127_85764_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 490.0
HKD1_k127_858016_0 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000002225 182.0
HKD1_k127_858016_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000006007 51.0
HKD1_k127_863043_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 408.0
HKD1_k127_863043_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 304.0
HKD1_k127_863043_2 Outer membrane efflux protein K12340,K15725 - - 0.00000000000000000000000000000000000000000000000000000004295 203.0
HKD1_k127_890989_0 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 537.0
HKD1_k127_890989_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 540.0
HKD1_k127_890989_2 energy transducer activity K03832 - - 0.00003087 48.0
HKD1_k127_890989_3 GDSL-like Lipase/Acylhydrolase - - - 0.00006956 54.0
HKD1_k127_899763_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 2.074e-210 660.0
HKD1_k127_899763_1 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000198 254.0
HKD1_k127_899763_2 superoxide reductase activity K05919 - 1.15.1.2 0.00000000000000006162 85.0
HKD1_k127_918483_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000001786 229.0
HKD1_k127_918483_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000008073 173.0
HKD1_k127_928511_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 528.0
HKD1_k127_928511_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 455.0
HKD1_k127_928511_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 414.0
HKD1_k127_928511_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000007616 175.0
HKD1_k127_928511_4 Cell division protein FtsQ K03589 - - 0.000000000000000000000000003851 122.0
HKD1_k127_928511_5 JAB/MPN domain - - - 0.0000000000005997 73.0
HKD1_k127_947679_1 - - - - 0.00001908 57.0
HKD1_k127_949236_0 2-hydroxyglutaryl-CoA dehydratase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 316.0
HKD1_k127_949236_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000006111 220.0
HKD1_k127_970683_0 hydrolase, family 65, central catalytic - - - 3.784e-289 911.0
HKD1_k127_970683_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000004235 219.0
HKD1_k127_970683_2 addiction module killer protein - - - 0.00000000000000000000000009263 108.0
HKD1_k127_970683_3 toxin-antitoxin pair type II binding - - - 0.0000000000000000001933 90.0
HKD1_k127_970683_4 PIN domain - - - 0.00001857 47.0
HKD1_k127_973617_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000001249 227.0
HKD1_k127_973617_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000002645 234.0
HKD1_k127_973617_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000004807 189.0
HKD1_k127_973617_3 L-rhamnose mutarotase K03534 - 5.1.3.32 0.00000000000000000000000000000000002148 137.0
HKD1_k127_984911_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 594.0
HKD1_k127_984911_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001899 259.0
HKD1_k127_984911_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 244.0
HKD1_k127_984911_3 - - - - 0.00000000000000000000005338 105.0
HKD1_k127_984911_4 - - - - 0.000003388 55.0