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Overview

ID MAG01761
Name HKD1_bin.80
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Myxococcota_A
Class UBA9160
Order SZUA-336
Family SZUA-336
Genus VGRW01
Species
Assembly information
Completeness (%) 98.31
Contamination (%) 1.77
GC content (%) 73.0
N50 (bp) 32,850
Genome size (bp) 4,523,430

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4012

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1083343_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.736e-244 787.0
HKD1_k127_1083343_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.725e-226 724.0
HKD1_k127_1083343_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 546.0
HKD1_k127_1083343_100 helix_turn_helix, mercury resistance - - - 0.00000000000000000000109 104.0
HKD1_k127_1083343_101 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000003099 106.0
HKD1_k127_1083343_102 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000001159 91.0
HKD1_k127_1083343_103 heat shock protein binding - - - 0.000000000000000003078 101.0
HKD1_k127_1083343_104 Phosphoribosyl-ATP K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.000000000000000006918 89.0
HKD1_k127_1083343_105 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.00000000000000001512 96.0
HKD1_k127_1083343_106 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000006158 86.0
HKD1_k127_1083343_107 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.00000000000001077 89.0
HKD1_k127_1083343_108 peptidoglycan binding - - - 0.000000000001406 80.0
HKD1_k127_1083343_109 HAD-hyrolase-like - - - 0.000000000003116 80.0
HKD1_k127_1083343_11 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 554.0
HKD1_k127_1083343_110 repeat protein - - - 0.000000000003587 82.0
HKD1_k127_1083343_111 bacterial OsmY and nodulation domain - - - 0.000000000004976 78.0
HKD1_k127_1083343_112 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000008725 74.0
HKD1_k127_1083343_113 Protein of unknown function (DUF503) K09764 - - 0.0000000001503 75.0
HKD1_k127_1083343_114 Methionine biosynthesis protein MetW - - - 0.000000001967 70.0
HKD1_k127_1083343_115 cell redox homeostasis - - - 0.000000009398 68.0
HKD1_k127_1083343_116 transcriptional regulator - - - 0.00000007686 66.0
HKD1_k127_1083343_117 PDZ domain (Also known as DHR or GLGF) - - - 0.0005785 52.0
HKD1_k127_1083343_12 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 532.0
HKD1_k127_1083343_13 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 554.0
HKD1_k127_1083343_14 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 528.0
HKD1_k127_1083343_15 histidine kinase, HAMP K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 525.0
HKD1_k127_1083343_16 Pro-kumamolisin, activation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 537.0
HKD1_k127_1083343_17 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 481.0
HKD1_k127_1083343_18 Hsp70 protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 489.0
HKD1_k127_1083343_19 response regulator K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 512.0
HKD1_k127_1083343_2 Protein of unknown function (DUF1254) - - - 1.863e-206 667.0
HKD1_k127_1083343_20 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 467.0
HKD1_k127_1083343_21 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 481.0
HKD1_k127_1083343_22 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 474.0
HKD1_k127_1083343_23 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 458.0
HKD1_k127_1083343_24 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 448.0
HKD1_k127_1083343_25 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 435.0
HKD1_k127_1083343_26 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 441.0
HKD1_k127_1083343_27 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 408.0
HKD1_k127_1083343_28 Aminotransferase class-III K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 431.0
HKD1_k127_1083343_29 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 391.0
HKD1_k127_1083343_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.32e-203 645.0
HKD1_k127_1083343_30 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 359.0
HKD1_k127_1083343_31 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 376.0
HKD1_k127_1083343_32 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 354.0
HKD1_k127_1083343_33 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 342.0
HKD1_k127_1083343_34 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 361.0
HKD1_k127_1083343_35 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 327.0
HKD1_k127_1083343_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 320.0
HKD1_k127_1083343_37 FAD binding domain K00103,K16653 - 1.1.3.8,1.1.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 334.0
HKD1_k127_1083343_38 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 299.0
HKD1_k127_1083343_39 Amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 301.0
HKD1_k127_1083343_4 Aldehyde dehydrogenase family - - - 4.808e-198 628.0
HKD1_k127_1083343_40 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 299.0
HKD1_k127_1083343_41 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 301.0
HKD1_k127_1083343_42 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 296.0
HKD1_k127_1083343_43 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 293.0
HKD1_k127_1083343_44 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001678 294.0
HKD1_k127_1083343_45 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003796 287.0
HKD1_k127_1083343_46 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001885 275.0
HKD1_k127_1083343_47 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001016 295.0
HKD1_k127_1083343_48 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002031 283.0
HKD1_k127_1083343_49 COGs COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000189 268.0
HKD1_k127_1083343_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 2.013e-197 620.0
HKD1_k127_1083343_50 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002007 254.0
HKD1_k127_1083343_51 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000326 251.0
HKD1_k127_1083343_52 XdhC Rossmann domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002631 250.0
HKD1_k127_1083343_53 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000003644 246.0
HKD1_k127_1083343_54 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000004974 250.0
HKD1_k127_1083343_55 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000004832 244.0
HKD1_k127_1083343_56 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000008809 226.0
HKD1_k127_1083343_57 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000008993 217.0
HKD1_k127_1083343_58 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000001807 241.0
HKD1_k127_1083343_59 Protein of unknown function (DUF4243) - - - 0.00000000000000000000000000000000000000000000000000000000007041 230.0
HKD1_k127_1083343_6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 618.0
HKD1_k127_1083343_60 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001463 231.0
HKD1_k127_1083343_61 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000001576 210.0
HKD1_k127_1083343_62 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000001813 209.0
HKD1_k127_1083343_63 pfam nudix - - - 0.000000000000000000000000000000000000000000000000000000003202 204.0
HKD1_k127_1083343_64 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000004875 196.0
HKD1_k127_1083343_65 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000004367 209.0
HKD1_k127_1083343_66 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000001041 193.0
HKD1_k127_1083343_67 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000002234 189.0
HKD1_k127_1083343_68 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000001163 196.0
HKD1_k127_1083343_69 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.000000000000000000000000000000000000000000000000008567 204.0
HKD1_k127_1083343_7 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 587.0
HKD1_k127_1083343_70 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000004688 201.0
HKD1_k127_1083343_71 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000003385 179.0
HKD1_k127_1083343_72 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000003504 192.0
HKD1_k127_1083343_73 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000001129 173.0
HKD1_k127_1083343_74 Oligosaccharide biosynthesis protein alg14 like - - - 0.0000000000000000000000000000000000000000000164 167.0
HKD1_k127_1083343_75 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000006273 171.0
HKD1_k127_1083343_76 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000001239 163.0
HKD1_k127_1083343_77 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000002987 169.0
HKD1_k127_1083343_78 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000003064 166.0
HKD1_k127_1083343_79 asparagine synthase - - - 0.00000000000000000000000000000000000000006162 175.0
HKD1_k127_1083343_8 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 559.0
HKD1_k127_1083343_80 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000002539 154.0
HKD1_k127_1083343_81 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000002598 160.0
HKD1_k127_1083343_83 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000001212 147.0
HKD1_k127_1083343_84 protein conserved in bacteria - - - 0.0000000000000000000000000000000000001736 150.0
HKD1_k127_1083343_85 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000007346 156.0
HKD1_k127_1083343_86 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000009531 142.0
HKD1_k127_1083343_87 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000008112 146.0
HKD1_k127_1083343_88 Helix-turn-helix domain - - - 0.000000000000000000000000000000001183 138.0
HKD1_k127_1083343_89 tetR family - - - 0.000000000000000000000000000000004271 146.0
HKD1_k127_1083343_9 GDP-mannose 4,6 dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 539.0
HKD1_k127_1083343_90 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000001349 141.0
HKD1_k127_1083343_91 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000001034 138.0
HKD1_k127_1083343_92 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000001906 137.0
HKD1_k127_1083343_93 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000006558 134.0
HKD1_k127_1083343_94 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000002834 119.0
HKD1_k127_1083343_95 PFAM response regulator receiver - - - 0.0000000000000000000000000002022 124.0
HKD1_k127_1083343_96 polysaccharide export protein K01991 - - 0.00000000000000000000000008219 123.0
HKD1_k127_1083343_97 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000169 121.0
HKD1_k127_1083343_98 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000002132 112.0
HKD1_k127_1083343_99 Polysaccharide deacetylase - - - 0.0000000000000000000000008912 116.0
HKD1_k127_1111835_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.412e-231 728.0
HKD1_k127_1111835_1 PFAM class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 572.0
HKD1_k127_1111835_10 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.00006359 55.0
HKD1_k127_1111835_2 acyl-CoA dehydrogenase K14448 - 1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 436.0
HKD1_k127_1111835_3 Nucleoside recognition K06374 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 353.0
HKD1_k127_1111835_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 328.0
HKD1_k127_1111835_5 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000002054 243.0
HKD1_k127_1111835_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000008255 136.0
HKD1_k127_1111835_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000379 134.0
HKD1_k127_1111835_8 sh3 domain protein K07184 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.000000001397 71.0
HKD1_k127_1111835_9 Bacterial type II and III secretion system protein - - - 0.00006137 54.0
HKD1_k127_1180644_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.593e-248 789.0
HKD1_k127_1180644_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 510.0
HKD1_k127_1180644_2 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003241 287.0
HKD1_k127_1180644_3 TrkA-C domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000261 282.0
HKD1_k127_1180644_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000005752 226.0
HKD1_k127_1180644_5 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
HKD1_k127_1180644_6 AraC family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000001527 204.0
HKD1_k127_1180644_7 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000009843 141.0
HKD1_k127_1180644_8 energy transducer activity K03832 - - 0.0002123 47.0
HKD1_k127_1202144_0 ATP-dependent DNA helicase RecQ K03169 - 5.99.1.2 0.0 1413.0
HKD1_k127_1202144_1 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 308.0
HKD1_k127_1202144_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 306.0
HKD1_k127_1202144_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000008349 136.0
HKD1_k127_1202144_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000001324 134.0
HKD1_k127_1202144_5 transcriptional regulator K16137 - - 0.000000000000000000000000000000006566 144.0
HKD1_k127_1202144_6 Belongs to the GARS family K01945 - 6.3.4.13 0.0000002627 59.0
HKD1_k127_1227374_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.059e-230 721.0
HKD1_k127_1227374_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 610.0
HKD1_k127_1227374_10 Guanylyl transferase CofC like K09931 - - 0.00000000000000000000000000291 128.0
HKD1_k127_1227374_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.0000000000000000000000000159 115.0
HKD1_k127_1227374_12 Belongs to the GcvT family K06980 - - 0.00000000000000000000000003558 116.0
HKD1_k127_1227374_13 - - - - 0.00000003594 66.0
HKD1_k127_1227374_14 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000001923 60.0
HKD1_k127_1227374_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 530.0
HKD1_k127_1227374_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 440.0
HKD1_k127_1227374_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001551 300.0
HKD1_k127_1227374_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002541 276.0
HKD1_k127_1227374_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002924 275.0
HKD1_k127_1227374_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000007195 240.0
HKD1_k127_1227374_8 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000006759 197.0
HKD1_k127_1227374_9 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000002009 141.0
HKD1_k127_1264266_0 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 597.0
HKD1_k127_1264266_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 467.0
HKD1_k127_1264266_10 cytochrome p450 K15468 - - 0.000000000000000000000000000000000000000001518 159.0
HKD1_k127_1264266_11 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.000000000000000000000000000000000006099 139.0
HKD1_k127_1264266_12 - - - - 0.00000000000000000000000000000001222 140.0
HKD1_k127_1264266_13 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000003587 125.0
HKD1_k127_1264266_14 PFAM Membrane protein of K08972 - - 0.000000000000000000000000000005506 123.0
HKD1_k127_1264266_15 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000002188 113.0
HKD1_k127_1264266_16 Phosphoglycerate mutase family - - - 0.000000000000000000000273 103.0
HKD1_k127_1264266_17 Acetyltransferase (GNAT) domain - - - 0.00000000002808 64.0
HKD1_k127_1264266_2 PFAM Peptidase family M20 M25 M40 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 411.0
HKD1_k127_1264266_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 307.0
HKD1_k127_1264266_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002526 276.0
HKD1_k127_1264266_5 CYTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002091 280.0
HKD1_k127_1264266_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000006299 250.0
HKD1_k127_1264266_7 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002566 233.0
HKD1_k127_1264266_8 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000002621 226.0
HKD1_k127_1264266_9 protein transport - - - 0.0000000000000000000000000000000000000000000000000000002299 200.0
HKD1_k127_1334790_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.033e-214 693.0
HKD1_k127_1334790_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 605.0
HKD1_k127_1334790_10 COG3000 Sterol desaturase - - - 0.000000000000000000000000000000000000000000006345 172.0
HKD1_k127_1334790_11 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000002576 169.0
HKD1_k127_1334790_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000001765 136.0
HKD1_k127_1334790_13 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000007031 132.0
HKD1_k127_1334790_14 - - - - 0.000000000000000000000000004964 116.0
HKD1_k127_1334790_15 Chromate resistance exported protein - - - 0.00000000000000000000000004229 124.0
HKD1_k127_1334790_16 major facilitator superfamily - - - 0.00000000000000000004621 104.0
HKD1_k127_1334790_2 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 417.0
HKD1_k127_1334790_3 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 327.0
HKD1_k127_1334790_4 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 329.0
HKD1_k127_1334790_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 265.0
HKD1_k127_1334790_6 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002961 260.0
HKD1_k127_1334790_7 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000002198 237.0
HKD1_k127_1334790_8 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000001576 215.0
HKD1_k127_1334790_9 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K18029 - 1.17.2.1 0.000000000000000000000000000000000000000000003722 171.0
HKD1_k127_1421670_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 509.0
HKD1_k127_1421670_1 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 417.0
HKD1_k127_1421670_10 2-phosphosulpholactate phosphatase - - - 0.0000000000000000000000000000000000000000000000000002 201.0
HKD1_k127_1421670_11 Domain of unknown function (DUF3291) - - - 0.0000000000000000000000000000000000000000000000000003043 189.0
HKD1_k127_1421670_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000004955 188.0
HKD1_k127_1421670_13 Heavy metal translocating P-type atpase - - - 0.0000000000000000000000000000000000000000000000006794 188.0
HKD1_k127_1421670_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000007716 165.0
HKD1_k127_1421670_15 MAPEG family - - - 0.000000000000000000000000000000000000000001231 169.0
HKD1_k127_1421670_16 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000007957 144.0
HKD1_k127_1421670_17 pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000008864 135.0
HKD1_k127_1421670_18 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000002931 119.0
HKD1_k127_1421670_19 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000001146 109.0
HKD1_k127_1421670_2 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 403.0
HKD1_k127_1421670_20 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000005525 113.0
HKD1_k127_1421670_21 Belongs to the peptidase S8 family - - - 0.00000000000000000001278 101.0
HKD1_k127_1421670_22 - - - - 0.0000000000000001638 89.0
HKD1_k127_1421670_23 - - - - 0.0000000000000002356 90.0
HKD1_k127_1421670_24 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000007282 83.0
HKD1_k127_1421670_25 Putative prokaryotic signal transducing protein - - - 0.0000000001148 73.0
HKD1_k127_1421670_26 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.000000009354 59.0
HKD1_k127_1421670_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 355.0
HKD1_k127_1421670_4 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 303.0
HKD1_k127_1421670_5 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 301.0
HKD1_k127_1421670_6 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007943 299.0
HKD1_k127_1421670_7 nitric oxide reductase activity K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002316 271.0
HKD1_k127_1421670_8 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007973 252.0
HKD1_k127_1421670_9 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000001172 234.0
HKD1_k127_1441787_0 Luciferase-like monooxygenase - - - 1.557e-216 687.0
HKD1_k127_1441787_1 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 552.0
HKD1_k127_1441787_10 Hemolysins and related proteins containing CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000132 243.0
HKD1_k127_1441787_11 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000007794 244.0
HKD1_k127_1441787_12 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) - - - 0.00000000000000000000000000000000000000000000000000001211 212.0
HKD1_k127_1441787_13 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000002199 209.0
HKD1_k127_1441787_14 Peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000006535 158.0
HKD1_k127_1441787_15 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000001334 154.0
HKD1_k127_1441787_16 Redoxin K03386 - 1.11.1.15 0.0000000000000000477 81.0
HKD1_k127_1441787_17 transcriptional regulator - - - 0.0000000000000001375 89.0
HKD1_k127_1441787_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 505.0
HKD1_k127_1441787_3 PFAM Cl- channel voltage-gated family protein K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 477.0
HKD1_k127_1441787_4 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 468.0
HKD1_k127_1441787_5 Enoyl-CoA hydratase/isomerase K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 434.0
HKD1_k127_1441787_6 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 398.0
HKD1_k127_1441787_7 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 340.0
HKD1_k127_1441787_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 300.0
HKD1_k127_1441787_9 chorismate binding enzyme K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000001217 254.0
HKD1_k127_1480749_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1098.0
HKD1_k127_1480749_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.591e-195 627.0
HKD1_k127_1480749_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000003219 148.0
HKD1_k127_1480749_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000005823 139.0
HKD1_k127_1480749_12 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000007324 142.0
HKD1_k127_1480749_13 helix_turn_helix, mercury resistance - - - 0.000000000000000000000001436 106.0
HKD1_k127_1480749_14 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000001014 55.0
HKD1_k127_1480749_2 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 636.0
HKD1_k127_1480749_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 292.0
HKD1_k127_1480749_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000229 271.0
HKD1_k127_1480749_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001493 250.0
HKD1_k127_1480749_6 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000001462 215.0
HKD1_k127_1480749_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000002546 188.0
HKD1_k127_1480749_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000009617 174.0
HKD1_k127_1480749_9 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000009944 164.0
HKD1_k127_1485335_0 aconitate hydratase - - - 0.0 1055.0
HKD1_k127_1485335_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.099e-291 907.0
HKD1_k127_1485335_10 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 548.0
HKD1_k127_1485335_11 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 496.0
HKD1_k127_1485335_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 493.0
HKD1_k127_1485335_13 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 475.0
HKD1_k127_1485335_14 sigma factor activity K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 461.0
HKD1_k127_1485335_15 cytochrome p450 - GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 467.0
HKD1_k127_1485335_16 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 421.0
HKD1_k127_1485335_17 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 423.0
HKD1_k127_1485335_18 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 408.0
HKD1_k127_1485335_19 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 396.0
HKD1_k127_1485335_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 9.323e-284 920.0
HKD1_k127_1485335_20 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 394.0
HKD1_k127_1485335_21 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 369.0
HKD1_k127_1485335_22 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 371.0
HKD1_k127_1485335_23 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 360.0
HKD1_k127_1485335_24 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 355.0
HKD1_k127_1485335_25 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 329.0
HKD1_k127_1485335_26 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 337.0
HKD1_k127_1485335_27 Belongs to the heat shock protein 70 family K04046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 343.0
HKD1_k127_1485335_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 313.0
HKD1_k127_1485335_29 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 322.0
HKD1_k127_1485335_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 2.9e-245 775.0
HKD1_k127_1485335_30 Lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 323.0
HKD1_k127_1485335_31 Dehydrogenase K00059 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 306.0
HKD1_k127_1485335_32 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000001211 268.0
HKD1_k127_1485335_33 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002299 278.0
HKD1_k127_1485335_34 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000048 261.0
HKD1_k127_1485335_35 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000004047 266.0
HKD1_k127_1485335_36 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000001311 237.0
HKD1_k127_1485335_37 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002224 245.0
HKD1_k127_1485335_38 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000006813 247.0
HKD1_k127_1485335_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000000008444 248.0
HKD1_k127_1485335_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.256e-237 746.0
HKD1_k127_1485335_40 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
HKD1_k127_1485335_41 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001109 232.0
HKD1_k127_1485335_42 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000006926 228.0
HKD1_k127_1485335_43 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000001827 218.0
HKD1_k127_1485335_44 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000233 215.0
HKD1_k127_1485335_45 Amino-transferase class IV K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000001934 212.0
HKD1_k127_1485335_46 - - - - 0.000000000000000000000000000000000000000000000000000000002325 206.0
HKD1_k127_1485335_47 Glutathione S-transferase K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000001004 213.0
HKD1_k127_1485335_48 Domain of unknown function (DUF1929) - - - 0.00000000000000000000000000000000000000000000000000000003222 225.0
HKD1_k127_1485335_49 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000006771 212.0
HKD1_k127_1485335_5 transcription factor binding K15836 - - 1.537e-230 729.0
HKD1_k127_1485335_50 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000007959 196.0
HKD1_k127_1485335_51 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000003702 203.0
HKD1_k127_1485335_52 KR domain - - - 0.000000000000000000000000000000000000000000000000000004608 214.0
HKD1_k127_1485335_53 - - - - 0.000000000000000000000000000000000000000000000000000009933 200.0
HKD1_k127_1485335_54 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000005273 191.0
HKD1_k127_1485335_55 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000102 198.0
HKD1_k127_1485335_56 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000001135 196.0
HKD1_k127_1485335_57 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000006929 185.0
HKD1_k127_1485335_58 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000006755 178.0
HKD1_k127_1485335_59 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000009147 176.0
HKD1_k127_1485335_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 604.0
HKD1_k127_1485335_60 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.00000000000000000000000000000000000000000001867 188.0
HKD1_k127_1485335_61 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000008246 156.0
HKD1_k127_1485335_62 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000006275 165.0
HKD1_k127_1485335_63 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000088 152.0
HKD1_k127_1485335_64 CHRD domain - - - 0.00000000000000000000000000000000000001028 152.0
HKD1_k127_1485335_65 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000001113 159.0
HKD1_k127_1485335_66 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000001392 146.0
HKD1_k127_1485335_67 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000002533 161.0
HKD1_k127_1485335_68 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001205 152.0
HKD1_k127_1485335_69 PEP-CTERM motif - - - 0.000000000000000000000000000000000004491 148.0
HKD1_k127_1485335_7 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 577.0
HKD1_k127_1485335_70 ASCH - - - 0.00000000000000000000000000000000003086 137.0
HKD1_k127_1485335_71 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000002448 144.0
HKD1_k127_1485335_72 Glycosyl hydrolases family 32 N-terminal domain K01193 - 3.2.1.26 0.00000000000000000000000000000004201 136.0
HKD1_k127_1485335_73 transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000001689 127.0
HKD1_k127_1485335_74 YCII-related domain - - - 0.0000000000000000000000000000002749 130.0
HKD1_k127_1485335_75 Major facilitator Superfamily K08217 - - 0.00000000000000000000000000002302 132.0
HKD1_k127_1485335_76 trisaccharide binding - - - 0.00000000000000000000000000003209 136.0
HKD1_k127_1485335_77 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000001137 120.0
HKD1_k127_1485335_78 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000001258 121.0
HKD1_k127_1485335_79 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000002308 99.0
HKD1_k127_1485335_8 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 582.0
HKD1_k127_1485335_80 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000927 103.0
HKD1_k127_1485335_81 Transcriptional regulator K03892 - - 0.0000000000000000001033 93.0
HKD1_k127_1485335_82 - - - - 0.00000000000000003388 90.0
HKD1_k127_1485335_84 Belongs to the UPF0235 family K09131 - - 0.00000000000001544 83.0
HKD1_k127_1485335_85 Domain of unknown function (DUF4180) - - - 0.00000000000002703 84.0
HKD1_k127_1485335_86 Peptidase family M48 - - - 0.0000000000005483 80.0
HKD1_k127_1485335_87 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000001362 77.0
HKD1_k127_1485335_88 Lysyl oxidase - - - 0.0000000001005 76.0
HKD1_k127_1485335_89 Thrombospondin type 3 repeat - - - 0.0000000003444 72.0
HKD1_k127_1485335_9 Cytochrome P450 K05917 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615 1.14.13.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 559.0
HKD1_k127_1485335_90 heparin binding K04659 GO:0001501,GO:0001968,GO:0002020,GO:0003416,GO:0003417,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005912,GO:0005924,GO:0005927,GO:0007155,GO:0007275,GO:0007517,GO:0008150,GO:0008201,GO:0008289,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010941,GO:0016043,GO:0016203,GO:0019842,GO:0019899,GO:0022610,GO:0030054,GO:0030055,GO:0030198,GO:0031012,GO:0032501,GO:0032502,GO:0032991,GO:0033627,GO:0035265,GO:0036094,GO:0040007,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043394,GO:0043395,GO:0044421,GO:0044877,GO:0046872,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048705,GO:0048731,GO:0048736,GO:0048856,GO:0050789,GO:0050794,GO:0051216,GO:0060173,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060538,GO:0060548,GO:0061061,GO:0061448,GO:0062023,GO:0065007,GO:0070161,GO:0071840,GO:0097159,GO:0097367,GO:0098868,GO:1901681 - 0.00000001887 68.0
HKD1_k127_1485335_91 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000001941 61.0
HKD1_k127_1485335_92 Polymer-forming cytoskeletal - - - 0.0000007086 63.0
HKD1_k127_1485335_93 - - - - 0.000003319 56.0
HKD1_k127_1485335_94 membrane - - - 0.000004765 50.0
HKD1_k127_1485335_95 PFAM glycosyl transferase family 9 - - - 0.000004855 57.0
HKD1_k127_1534390_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 589.0
HKD1_k127_1534390_1 Carbohydrate-selective porin, OprB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 573.0
HKD1_k127_1534390_10 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 308.0
HKD1_k127_1534390_11 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002647 297.0
HKD1_k127_1534390_12 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000026 288.0
HKD1_k127_1534390_13 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006326 271.0
HKD1_k127_1534390_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002854 263.0
HKD1_k127_1534390_15 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000002479 244.0
HKD1_k127_1534390_16 F420-dependent oxidoreductase, MSMEG_2256 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006767 243.0
HKD1_k127_1534390_17 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000006284 242.0
HKD1_k127_1534390_18 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000007392 219.0
HKD1_k127_1534390_19 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000005139 202.0
HKD1_k127_1534390_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 563.0
HKD1_k127_1534390_20 PFAM Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000003223 191.0
HKD1_k127_1534390_21 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000001801 192.0
HKD1_k127_1534390_22 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000008461 179.0
HKD1_k127_1534390_23 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000354 166.0
HKD1_k127_1534390_24 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000006412 136.0
HKD1_k127_1534390_25 SmpA / OmlA family - - - 0.000000000000000000000000000001272 129.0
HKD1_k127_1534390_26 Putative DNA-binding domain - - - 0.000000000000000000000000003467 121.0
HKD1_k127_1534390_27 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000005664 85.0
HKD1_k127_1534390_28 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000003528 68.0
HKD1_k127_1534390_29 - - - - 0.00001277 59.0
HKD1_k127_1534390_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 572.0
HKD1_k127_1534390_30 - - - - 0.00005392 54.0
HKD1_k127_1534390_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 480.0
HKD1_k127_1534390_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 469.0
HKD1_k127_1534390_6 FAD binding domain K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 459.0
HKD1_k127_1534390_7 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 365.0
HKD1_k127_1534390_8 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 349.0
HKD1_k127_1534390_9 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 324.0
HKD1_k127_1689624_0 Protein export membrane protein K03296,K18138 - - 0.0 1195.0
HKD1_k127_1689624_1 PQQ enzyme repeat - - - 6.2e-220 700.0
HKD1_k127_1689624_10 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 462.0
HKD1_k127_1689624_100 response regulator, receiver K03413 - - 0.000000000000000281 91.0
HKD1_k127_1689624_101 oligoendopeptidase F - - - 0.0000000000002333 82.0
HKD1_k127_1689624_102 - - - - 0.0000000000005019 72.0
HKD1_k127_1689624_103 - - - - 0.000000000009747 68.0
HKD1_k127_1689624_104 - - - - 0.00000000001218 75.0
HKD1_k127_1689624_105 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.00000000008766 72.0
HKD1_k127_1689624_106 Helix-turn-helix domain - - - 0.00000001536 67.0
HKD1_k127_1689624_107 Subtilase family K14743 - - 0.0000001396 65.0
HKD1_k127_1689624_108 - - - - 0.000005684 57.0
HKD1_k127_1689624_109 EamA-like transporter family - - - 0.00003802 58.0
HKD1_k127_1689624_11 Peptidase dimerisation domain K01439,K13049 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 463.0
HKD1_k127_1689624_110 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0002295 48.0
HKD1_k127_1689624_111 PFAM luciferase-like - - - 0.0005172 52.0
HKD1_k127_1689624_112 Evidence 4 Homologs of previously reported genes of - - - 0.0005784 51.0
HKD1_k127_1689624_12 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 464.0
HKD1_k127_1689624_13 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 456.0
HKD1_k127_1689624_14 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 469.0
HKD1_k127_1689624_15 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 454.0
HKD1_k127_1689624_16 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 428.0
HKD1_k127_1689624_17 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 419.0
HKD1_k127_1689624_18 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 447.0
HKD1_k127_1689624_19 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 412.0
HKD1_k127_1689624_2 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 2.84e-208 656.0
HKD1_k127_1689624_20 PFAM amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 400.0
HKD1_k127_1689624_21 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 384.0
HKD1_k127_1689624_22 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 380.0
HKD1_k127_1689624_23 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 379.0
HKD1_k127_1689624_24 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 368.0
HKD1_k127_1689624_25 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 381.0
HKD1_k127_1689624_26 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 349.0
HKD1_k127_1689624_27 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 364.0
HKD1_k127_1689624_28 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 334.0
HKD1_k127_1689624_29 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 340.0
HKD1_k127_1689624_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 582.0
HKD1_k127_1689624_30 zinc finger K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 346.0
HKD1_k127_1689624_31 COG2211 Na melibiose symporter and related transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 339.0
HKD1_k127_1689624_32 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 342.0
HKD1_k127_1689624_33 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 327.0
HKD1_k127_1689624_34 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 331.0
HKD1_k127_1689624_35 glycosyl transferase family 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 332.0
HKD1_k127_1689624_36 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 317.0
HKD1_k127_1689624_37 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
HKD1_k127_1689624_38 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 306.0
HKD1_k127_1689624_39 Epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007302 301.0
HKD1_k127_1689624_4 TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 543.0
HKD1_k127_1689624_40 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007667 291.0
HKD1_k127_1689624_41 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002083 284.0
HKD1_k127_1689624_42 Sigma-54 interaction domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006007 299.0
HKD1_k127_1689624_43 beta-galactosidase activity K01190,K12308,K12373 - 3.2.1.23,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009198 290.0
HKD1_k127_1689624_44 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002859 260.0
HKD1_k127_1689624_45 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001012 266.0
HKD1_k127_1689624_46 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
HKD1_k127_1689624_47 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000004695 253.0
HKD1_k127_1689624_48 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007423 277.0
HKD1_k127_1689624_49 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000004618 263.0
HKD1_k127_1689624_5 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 516.0
HKD1_k127_1689624_50 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000142 270.0
HKD1_k127_1689624_51 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
HKD1_k127_1689624_52 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003146 239.0
HKD1_k127_1689624_53 Psort location Cytoplasmic, score K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000007344 240.0
HKD1_k127_1689624_54 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000002425 235.0
HKD1_k127_1689624_55 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000004723 231.0
HKD1_k127_1689624_56 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000005928 241.0
HKD1_k127_1689624_57 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000006896 228.0
HKD1_k127_1689624_58 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000953 221.0
HKD1_k127_1689624_59 Male sterility K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000008996 218.0
HKD1_k127_1689624_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 514.0
HKD1_k127_1689624_60 chondroitin AC lyase activity - - - 0.000000000000000000000000000000000000000000000000000000006393 209.0
HKD1_k127_1689624_61 TIGRFAM phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000672 213.0
HKD1_k127_1689624_62 FR47-like protein K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000001959 203.0
HKD1_k127_1689624_63 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000005608 201.0
HKD1_k127_1689624_64 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000002594 179.0
HKD1_k127_1689624_65 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000001473 190.0
HKD1_k127_1689624_66 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000002438 175.0
HKD1_k127_1689624_67 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000886 177.0
HKD1_k127_1689624_68 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000135 180.0
HKD1_k127_1689624_69 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000004692 171.0
HKD1_k127_1689624_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 502.0
HKD1_k127_1689624_70 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000004287 173.0
HKD1_k127_1689624_71 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000005003 166.0
HKD1_k127_1689624_72 methyltransferase - - - 0.00000000000000000000000000000000000002239 163.0
HKD1_k127_1689624_73 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000001073 159.0
HKD1_k127_1689624_74 MlaC protein K07323 - - 0.000000000000000000000000000000000001082 149.0
HKD1_k127_1689624_75 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000002064 146.0
HKD1_k127_1689624_76 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000002095 155.0
HKD1_k127_1689624_77 Gnat family - - - 0.00000000000000000000000000000000002482 150.0
HKD1_k127_1689624_78 Pantothenate kinase K09680 - 2.7.1.33 0.00000000000000000000000000000001133 138.0
HKD1_k127_1689624_79 domain, Protein - - - 0.00000000000000000000000000000003102 145.0
HKD1_k127_1689624_8 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 495.0
HKD1_k127_1689624_80 Rhomboid family K09650 - 3.4.21.105 0.0000000000000000000000000000008882 139.0
HKD1_k127_1689624_81 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000002565 137.0
HKD1_k127_1689624_82 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000005351 132.0
HKD1_k127_1689624_83 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000001717 117.0
HKD1_k127_1689624_84 SnoaL-like domain - - - 0.0000000000000000000000000003201 124.0
HKD1_k127_1689624_85 Bifunctional nuclease K08999 - - 0.0000000000000000000000000003629 121.0
HKD1_k127_1689624_86 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000199 116.0
HKD1_k127_1689624_87 Phosphoribosyl transferase domain - - - 0.00000000000000000000000002861 116.0
HKD1_k127_1689624_88 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000002987 106.0
HKD1_k127_1689624_89 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000009184 107.0
HKD1_k127_1689624_9 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 469.0
HKD1_k127_1689624_90 - - - - 0.000000000000000000000001953 111.0
HKD1_k127_1689624_91 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000001548 108.0
HKD1_k127_1689624_92 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000005805 94.0
HKD1_k127_1689624_93 Protein of unknown function (DUF1329) - - - 0.0000000000000000001313 99.0
HKD1_k127_1689624_94 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000001349 101.0
HKD1_k127_1689624_95 PFAM PfkB domain protein - - - 0.0000000000000000009785 96.0
HKD1_k127_1689624_97 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.00000000000000007086 94.0
HKD1_k127_1689624_98 START domain - - - 0.0000000000000001096 96.0
HKD1_k127_1689624_99 Domain of unknown function (DUF3332) - - - 0.0000000000000001954 87.0
HKD1_k127_172488_0 DEAD DEAH box helicase K03724 - - 0.0 1335.0
HKD1_k127_172488_1 Dehydrogenase E1 component K00164 - 1.2.4.2 1.262e-275 876.0
HKD1_k127_172488_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 322.0
HKD1_k127_172488_11 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 327.0
HKD1_k127_172488_12 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 321.0
HKD1_k127_172488_13 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 316.0
HKD1_k127_172488_14 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007613 290.0
HKD1_k127_172488_15 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008186 274.0
HKD1_k127_172488_16 Hsp33 protein K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004307 256.0
HKD1_k127_172488_17 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000002144 272.0
HKD1_k127_172488_18 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001096 257.0
HKD1_k127_172488_19 Fe-S oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000000000000000003126 227.0
HKD1_k127_172488_2 Belongs to the peptidase S8 family K14645 - - 2.302e-195 658.0
HKD1_k127_172488_20 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000006321 190.0
HKD1_k127_172488_21 Cupin domain - - - 0.000000000000000000000000000000000000000000009719 166.0
HKD1_k127_172488_22 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000003613 130.0
HKD1_k127_172488_23 Rieske-like [2Fe-2S] domain - - - 0.000000000000000000002292 105.0
HKD1_k127_172488_24 LUD domain K00782 - - 0.00000000000000001855 92.0
HKD1_k127_172488_25 transcriptional regulator - - - 0.0000000000000002 88.0
HKD1_k127_172488_27 - - - - 0.0000000000003521 78.0
HKD1_k127_172488_28 Thrombospondin type 3 repeat - - - 0.00000000001591 71.0
HKD1_k127_172488_29 PFAM aminoglycoside phosphotransferase - - - 0.000002734 59.0
HKD1_k127_172488_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 454.0
HKD1_k127_172488_4 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 464.0
HKD1_k127_172488_5 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 385.0
HKD1_k127_172488_6 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 351.0
HKD1_k127_172488_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 340.0
HKD1_k127_172488_8 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 323.0
HKD1_k127_172488_9 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 337.0
HKD1_k127_1758082_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000005218 266.0
HKD1_k127_1758082_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001141 267.0
HKD1_k127_1758082_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000495 175.0
HKD1_k127_1758082_3 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000002228 150.0
HKD1_k127_1758082_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000001525 124.0
HKD1_k127_1758082_5 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000001224 109.0
HKD1_k127_1758082_6 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000001104 93.0
HKD1_k127_1758082_7 PilZ domain - - - 0.000004681 57.0
HKD1_k127_177772_0 DEAD DEAH box helicase - - - 1.034e-264 840.0
HKD1_k127_177772_1 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 5.761e-250 808.0
HKD1_k127_177772_10 DNA binding domain - - - 0.00000000000000000000000000000000000001187 150.0
HKD1_k127_177772_11 Belongs to the BolA IbaG family - - - 0.00000000000000004441 83.0
HKD1_k127_177772_2 Amidohydrolase family - - - 3.663e-209 683.0
HKD1_k127_177772_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 376.0
HKD1_k127_177772_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 374.0
HKD1_k127_177772_5 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 323.0
HKD1_k127_177772_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 324.0
HKD1_k127_177772_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001522 301.0
HKD1_k127_177772_8 Belongs to the ABC transporter superfamily K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000003314 243.0
HKD1_k127_177772_9 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000003407 180.0
HKD1_k127_1824678_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 424.0
HKD1_k127_1824678_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004113 267.0
HKD1_k127_1824678_2 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000001609 165.0
HKD1_k127_1824678_3 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000000000003086 136.0
HKD1_k127_1824678_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000112 73.0
HKD1_k127_190910_0 Proteasomal ATPase OB/ID domain K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 3.374e-209 667.0
HKD1_k127_190910_1 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 591.0
HKD1_k127_190910_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 594.0
HKD1_k127_190910_3 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005442 262.0
HKD1_k127_190910_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000005466 182.0
HKD1_k127_190910_5 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000008691 111.0
HKD1_k127_190910_6 Pup-like protein K13570 - - 0.00000000207 63.0
HKD1_k127_1995233_0 Chromosome Partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000161 233.0
HKD1_k127_1995233_1 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000007096 200.0
HKD1_k127_1995233_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000009053 153.0
HKD1_k127_1995233_3 NUDIX domain - - - 0.0000000000000000000000000000000000004603 147.0
HKD1_k127_1995233_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K01083,K01113,K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.1,3.1.3.5,3.1.3.8 0.00000000000000000000000000000000004199 152.0
HKD1_k127_1995233_5 - - - - 0.0000000000000000000000002248 119.0
HKD1_k127_1995233_6 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000005302 63.0
HKD1_k127_2046650_0 Flavin-binding monooxygenase-like K03379,K21730 - 1.14.13.160,1.14.13.22 4.586e-257 801.0
HKD1_k127_2046650_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.273e-215 681.0
HKD1_k127_2046650_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001486 265.0
HKD1_k127_2046650_3 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003467 262.0
HKD1_k127_2046650_4 - - - - 0.000000000000000000000000000000000000000000000000000004557 205.0
HKD1_k127_2046650_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000181 187.0
HKD1_k127_2046650_7 - - - - 0.000003359 57.0
HKD1_k127_2051703_0 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 557.0
HKD1_k127_2051703_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 511.0
HKD1_k127_2051703_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 329.0
HKD1_k127_2051703_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 309.0
HKD1_k127_2051703_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
HKD1_k127_2051703_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000001513 236.0
HKD1_k127_2051703_6 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000001675 71.0
HKD1_k127_2051924_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1165.0
HKD1_k127_2051924_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.488e-212 674.0
HKD1_k127_2051924_10 - - - - 0.000000000000000000000000000000000000000000000000000000000001127 236.0
HKD1_k127_2051924_11 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000001382 226.0
HKD1_k127_2051924_12 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000004996 204.0
HKD1_k127_2051924_13 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000006487 204.0
HKD1_k127_2051924_14 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000003377 206.0
HKD1_k127_2051924_15 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000756 203.0
HKD1_k127_2051924_16 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 GO:0000041,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006826,GO:0008150,GO:0008152,GO:0008823,GO:0015677,GO:0015682,GO:0016020,GO:0016021,GO:0016491,GO:0016722,GO:0016723,GO:0030001,GO:0031224,GO:0031226,GO:0033216,GO:0034220,GO:0034755,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0052851,GO:0055085,GO:0055114,GO:0071944,GO:0072512,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098706,GO:0098711,GO:0098739,GO:0099587 1.5.1.40 0.000000000000000000000000000000000000000000001054 173.0
HKD1_k127_2051924_17 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000000000000003712 168.0
HKD1_k127_2051924_18 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000002548 154.0
HKD1_k127_2051924_19 Pfam:DUF385 - - - 0.000000000000000000000000000001288 126.0
HKD1_k127_2051924_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 507.0
HKD1_k127_2051924_20 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000005807 120.0
HKD1_k127_2051924_21 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000002122 129.0
HKD1_k127_2051924_22 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000005858 113.0
HKD1_k127_2051924_23 Amidinotransferase - GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813 - 0.00000000000000000000001982 117.0
HKD1_k127_2051924_24 Cupin 2, conserved barrel domain protein - - - 0.00000001267 61.0
HKD1_k127_2051924_25 - - - - 0.00000002304 63.0
HKD1_k127_2051924_26 TPR repeat - - - 0.00000002763 65.0
HKD1_k127_2051924_27 SMART Transcription regulator LuxR, C-terminal - - - 0.000003097 59.0
HKD1_k127_2051924_3 Mismatch repair ATPase (MutS family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 519.0
HKD1_k127_2051924_4 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 443.0
HKD1_k127_2051924_5 Succinylglutamic semialdehyde dehydrogenase K06447 - 1.2.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 376.0
HKD1_k127_2051924_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 292.0
HKD1_k127_2051924_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000154 295.0
HKD1_k127_2051924_8 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000395 294.0
HKD1_k127_2051924_9 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001305 288.0
HKD1_k127_2058358_0 N-acyl-D-aspartate D-glutamate deacylase - - - 1.11e-221 701.0
HKD1_k127_2058358_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 582.0
HKD1_k127_2058358_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 375.0
HKD1_k127_2058358_11 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 378.0
HKD1_k127_2058358_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 347.0
HKD1_k127_2058358_13 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 307.0
HKD1_k127_2058358_14 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000001698 274.0
HKD1_k127_2058358_15 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000002683 274.0
HKD1_k127_2058358_16 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000002517 254.0
HKD1_k127_2058358_17 PFAM Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000005796 225.0
HKD1_k127_2058358_18 Uridine phosphorylase K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000001117 186.0
HKD1_k127_2058358_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000252 180.0
HKD1_k127_2058358_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 541.0
HKD1_k127_2058358_20 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000001565 182.0
HKD1_k127_2058358_21 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000009181 174.0
HKD1_k127_2058358_23 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000002027 139.0
HKD1_k127_2058358_24 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000003612 127.0
HKD1_k127_2058358_25 - - - - 0.000000000000000000000000000003522 123.0
HKD1_k127_2058358_26 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000004866 125.0
HKD1_k127_2058358_27 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000009796 111.0
HKD1_k127_2058358_28 Endoribonuclease L-PSP - - - 0.000000000000000000000001878 108.0
HKD1_k127_2058358_29 CopC domain - - - 0.000000000000000000000005916 110.0
HKD1_k127_2058358_3 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 517.0
HKD1_k127_2058358_30 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000001023 102.0
HKD1_k127_2058358_31 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000001471 90.0
HKD1_k127_2058358_32 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000501 95.0
HKD1_k127_2058358_33 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000009395 75.0
HKD1_k127_2058358_34 YXWGXW repeat (2 copies) - - - 0.0000001742 59.0
HKD1_k127_2058358_35 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00004831 55.0
HKD1_k127_2058358_36 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0005476 51.0
HKD1_k127_2058358_4 Copper resistance protein D K07245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 498.0
HKD1_k127_2058358_5 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 477.0
HKD1_k127_2058358_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 458.0
HKD1_k127_2058358_7 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 445.0
HKD1_k127_2058358_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 433.0
HKD1_k127_2058358_9 Na melibiose symporter and related transporters K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 438.0
HKD1_k127_2079956_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 5.239e-312 983.0
HKD1_k127_2079956_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 321.0
HKD1_k127_2079956_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001179 274.0
HKD1_k127_2079956_3 alpha-ribazole phosphatase activity K01834,K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.11,5.4.2.12 0.00000000000000000000000000000000000000000257 168.0
HKD1_k127_2079956_4 Stress responsive A/B Barrel Domain - - - 0.00000000000000000003002 105.0
HKD1_k127_2096582_0 Glycogen debranching enzyme - - - 0.0 1420.0
HKD1_k127_2096582_1 cytochrome C peroxidase - - - 3.645e-311 978.0
HKD1_k127_2096582_10 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000002106 212.0
HKD1_k127_2096582_11 Alginate export - - - 0.0000000000000000000000000000000000000000000000000544 204.0
HKD1_k127_2096582_12 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000007422 180.0
HKD1_k127_2096582_13 VIT family - - - 0.0000000000000000000000000000000000008852 162.0
HKD1_k127_2096582_14 Glyoxalase-like domain - - - 0.0000000000000000000000000000000008382 145.0
HKD1_k127_2096582_15 GAF domain K07673 - 2.7.13.3 0.0000000000000001111 93.0
HKD1_k127_2096582_16 - - - - 0.00000000000004836 73.0
HKD1_k127_2096582_17 transcriptional regulator K13770 - - 0.000000001959 66.0
HKD1_k127_2096582_18 - - - - 0.000006375 54.0
HKD1_k127_2096582_2 Carbamoyltransferase C-terminus K00612 - - 2.805e-264 829.0
HKD1_k127_2096582_3 alpha amylase, catalytic region - - - 8.731e-243 763.0
HKD1_k127_2096582_4 Arginine K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 606.0
HKD1_k127_2096582_5 Acyl-CoA dehydrogenase type 2 domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 535.0
HKD1_k127_2096582_6 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 441.0
HKD1_k127_2096582_7 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 335.0
HKD1_k127_2096582_8 COG4313 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 303.0
HKD1_k127_2096582_9 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 294.0
HKD1_k127_2104129_0 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 484.0
HKD1_k127_2104129_1 Mate efflux family protein K03327 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 469.0
HKD1_k127_2104129_10 unusual protein kinase K03688 - - 0.0000000000000000000000000000000000000000000000000000001709 211.0
HKD1_k127_2104129_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000007325 110.0
HKD1_k127_2104129_12 PFAM CBS domain containing protein K07168 - - 0.0000000000000000000000009479 108.0
HKD1_k127_2104129_13 Gamma-glutamyl cyclotransferase, AIG2-like K09000 - - 0.00000000000000000005406 102.0
HKD1_k127_2104129_14 - - - - 0.00000000000000002137 87.0
HKD1_k127_2104129_15 transcriptional regulator - - - 0.0000000000003557 78.0
HKD1_k127_2104129_16 Uroporphyrinogen-III synthase HemD K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000001608 64.0
HKD1_k127_2104129_17 - - - - 0.0000005727 62.0
HKD1_k127_2104129_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 445.0
HKD1_k127_2104129_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 400.0
HKD1_k127_2104129_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 339.0
HKD1_k127_2104129_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002888 282.0
HKD1_k127_2104129_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000002491 252.0
HKD1_k127_2104129_7 monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009941 263.0
HKD1_k127_2104129_8 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000002219 240.0
HKD1_k127_2104129_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001234 231.0
HKD1_k127_2107586_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.492e-291 938.0
HKD1_k127_2107586_1 Luciferase-like monooxygenase - - - 3.01e-207 651.0
HKD1_k127_2107586_10 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000002566 186.0
HKD1_k127_2107586_11 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000008689 164.0
HKD1_k127_2107586_12 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000003189 158.0
HKD1_k127_2107586_13 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000001083 87.0
HKD1_k127_2107586_14 domain, Protein K00703,K07082 - 2.4.1.21 0.00000000009922 72.0
HKD1_k127_2107586_15 ATP-binding region, ATPase domain protein - - - 0.0000001781 64.0
HKD1_k127_2107586_16 Von Willebrand factor type A K07114 - - 0.00003383 56.0
HKD1_k127_2107586_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.948e-199 661.0
HKD1_k127_2107586_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 500.0
HKD1_k127_2107586_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 448.0
HKD1_k127_2107586_5 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 406.0
HKD1_k127_2107586_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 304.0
HKD1_k127_2107586_7 Serine aminopeptidase, S33 K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001516 287.0
HKD1_k127_2107586_8 phospholipase C K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000003877 216.0
HKD1_k127_2107586_9 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000001152 187.0
HKD1_k127_2137445_0 Flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 615.0
HKD1_k127_2137445_1 dioxygenase K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 489.0
HKD1_k127_2137445_10 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000006495 226.0
HKD1_k127_2137445_11 IMP cyclohydrolase activity K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000005314 199.0
HKD1_k127_2137445_12 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000000000000000000000000006035 177.0
HKD1_k127_2137445_13 PFAM glycosyl transferase family 9 - - - 0.00000000000000000000000000000000001583 156.0
HKD1_k127_2137445_14 ACT domain - - - 0.000000000000000000000000003538 123.0
HKD1_k127_2137445_15 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000000000153 108.0
HKD1_k127_2137445_16 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000008229 89.0
HKD1_k127_2137445_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000001383 94.0
HKD1_k127_2137445_18 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000001129 74.0
HKD1_k127_2137445_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000002087 74.0
HKD1_k127_2137445_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 408.0
HKD1_k127_2137445_20 Methyltransferase domain - - - 0.00000002173 68.0
HKD1_k127_2137445_21 COG1716 FOG FHA domain - - - 0.0000001291 64.0
HKD1_k127_2137445_22 Acyl-CoA dehydrogenase, middle domain - - - 0.000001052 51.0
HKD1_k127_2137445_24 gag-polyprotein putative aspartyl protease - - - 0.00009355 52.0
HKD1_k127_2137445_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 383.0
HKD1_k127_2137445_4 COG0477 Permeases of the major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 385.0
HKD1_k127_2137445_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 347.0
HKD1_k127_2137445_6 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 302.0
HKD1_k127_2137445_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003109 294.0
HKD1_k127_2137445_8 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005408 276.0
HKD1_k127_2137445_9 acyl-CoA dehydrogenase K20035 - - 0.000000000000000000000000000000000000000000000000000000000000000000001946 263.0
HKD1_k127_2164903_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 529.0
HKD1_k127_2164903_1 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 511.0
HKD1_k127_2164903_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582,K16201 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000003762 226.0
HKD1_k127_2164903_11 transport system involved in gliding motility, auxiliary component - - - 0.000000000000000000000000000000000000000000000000000000002542 226.0
HKD1_k127_2164903_12 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000001169 204.0
HKD1_k127_2164903_13 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000002109 219.0
HKD1_k127_2164903_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000008091 200.0
HKD1_k127_2164903_15 PFAM Glycosyl transferase, group 1 K02844 - - 0.000000000000000000000000000000000000000000000000004599 196.0
HKD1_k127_2164903_16 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000004645 179.0
HKD1_k127_2164903_17 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000001885 145.0
HKD1_k127_2164903_18 Belongs to the HesB IscA family K13628,K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.000000000000000000000000000007551 122.0
HKD1_k127_2164903_19 Domain of unknown function (DUF4340) - - - 0.000000000000000000006826 107.0
HKD1_k127_2164903_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 404.0
HKD1_k127_2164903_20 Polymer-forming cytoskeletal - - - 0.0000000000000000002687 102.0
HKD1_k127_2164903_21 NnrU protein - - - 0.0000000000000002119 89.0
HKD1_k127_2164903_22 Outer membrane lipoprotein-sorting protein - - - 0.000000000000007717 84.0
HKD1_k127_2164903_23 PFAM ABC-2 type transporter K01992 - - 0.00000000000001764 88.0
HKD1_k127_2164903_24 NifU-like domain - - - 0.000000000002236 72.0
HKD1_k127_2164903_25 Peptidase MA superfamily - - - 0.000000003096 69.0
HKD1_k127_2164903_26 iron-sulfur transferase activity K22068 GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005198,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008033,GO:0008150,GO:0008152,GO:0008198,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031974,GO:0032947,GO:0034470,GO:0034641,GO:0034660,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044571,GO:0046483,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097428,GO:0098771,GO:1901360,GO:1901564 - 0.000001606 62.0
HKD1_k127_2164903_27 Outer membrane lipoprotein-sorting protein - - - 0.0003634 51.0
HKD1_k127_2164903_28 serine threonine protein kinase - - - 0.0005853 52.0
HKD1_k127_2164903_3 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 388.0
HKD1_k127_2164903_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 373.0
HKD1_k127_2164903_5 nitrogen compound transport K02033,K15581 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 314.0
HKD1_k127_2164903_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002922 246.0
HKD1_k127_2164903_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000002638 253.0
HKD1_k127_2164903_8 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000002851 245.0
HKD1_k127_2164903_9 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000007009 244.0
HKD1_k127_2193074_0 Domain of unknown function (DUF4082) - - - 0.0 1240.0
HKD1_k127_2193074_1 PFAM Cation H exchanger K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 536.0
HKD1_k127_2193074_10 - - - - 0.00000000000000000001843 93.0
HKD1_k127_2193074_11 Ion channel - - - 0.00000000000000008492 96.0
HKD1_k127_2193074_12 Lamin Tail Domain - - - 0.00000001058 70.0
HKD1_k127_2193074_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 428.0
HKD1_k127_2193074_3 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 376.0
HKD1_k127_2193074_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 320.0
HKD1_k127_2193074_5 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001402 277.0
HKD1_k127_2193074_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000004195 202.0
HKD1_k127_2193074_7 protein conserved in bacteria K04750 - - 0.000000000000000000000000000000000000000000008762 167.0
HKD1_k127_2193074_8 Fibrinogen-related domains (FReDs) - - - 0.0000000000000000000000002086 123.0
HKD1_k127_2193074_9 - - - - 0.000000000000000000000007048 115.0
HKD1_k127_2215861_0 Glycosyl Transferase - - - 5.723e-269 856.0
HKD1_k127_2215861_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 8.865e-256 805.0
HKD1_k127_2215861_10 Dihydrouridine synthase (Dus) - - - 0.000000000000000000000000000000000000003755 158.0
HKD1_k127_2215861_11 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000001273 55.0
HKD1_k127_2215861_12 Tyrosine phosphatase K00619 - 2.3.1.1 0.00006222 50.0
HKD1_k127_2215861_14 Serine threonine protein kinase - - - 0.0009369 52.0
HKD1_k127_2215861_2 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 567.0
HKD1_k127_2215861_3 Aldo/keto reductase family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 537.0
HKD1_k127_2215861_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 393.0
HKD1_k127_2215861_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 324.0
HKD1_k127_2215861_6 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 312.0
HKD1_k127_2215861_7 NnrU protein K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
HKD1_k127_2215861_8 Enoyl-(Acyl carrier protein) reductase K19811 - 1.1.1.357 0.000000000000000000000000000000000000000000000000000000000000000004821 250.0
HKD1_k127_2215861_9 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000001667 213.0
HKD1_k127_2220377_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1435.0
HKD1_k127_2220377_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.657e-241 773.0
HKD1_k127_2220377_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 292.0
HKD1_k127_2220377_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002272 283.0
HKD1_k127_2220377_12 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001589 287.0
HKD1_k127_2220377_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008715 255.0
HKD1_k127_2220377_14 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000006636 242.0
HKD1_k127_2220377_15 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000001522 206.0
HKD1_k127_2220377_16 Belongs to the peptidase S26 family K03100 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 0.000000000000000000000000000000000000000000000000000000006013 208.0
HKD1_k127_2220377_17 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000009084 204.0
HKD1_k127_2220377_18 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001609 200.0
HKD1_k127_2220377_19 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000006069 197.0
HKD1_k127_2220377_2 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 536.0
HKD1_k127_2220377_20 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006615 192.0
HKD1_k127_2220377_21 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000003307 186.0
HKD1_k127_2220377_22 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000008677 192.0
HKD1_k127_2220377_23 Ribosomal protein S13/S18 K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001667 181.0
HKD1_k127_2220377_24 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000002565 198.0
HKD1_k127_2220377_25 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001344 169.0
HKD1_k127_2220377_26 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000403 150.0
HKD1_k127_2220377_27 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000002382 156.0
HKD1_k127_2220377_28 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000009348 147.0
HKD1_k127_2220377_29 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000008505 135.0
HKD1_k127_2220377_3 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 464.0
HKD1_k127_2220377_30 Thioredoxin-like - - - 0.0000000000000000000000000000002226 135.0
HKD1_k127_2220377_31 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000004642 119.0
HKD1_k127_2220377_32 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000511 128.0
HKD1_k127_2220377_33 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000004509 114.0
HKD1_k127_2220377_34 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000001782 113.0
HKD1_k127_2220377_35 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001067 111.0
HKD1_k127_2220377_36 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001374 107.0
HKD1_k127_2220377_37 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000009675 106.0
HKD1_k127_2220377_38 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000114 87.0
HKD1_k127_2220377_39 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000008823 74.0
HKD1_k127_2220377_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 441.0
HKD1_k127_2220377_40 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000008185 71.0
HKD1_k127_2220377_41 Ribosomal protein L30p/L7e K02907 - - 0.0000000001403 74.0
HKD1_k127_2220377_42 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00004775 55.0
HKD1_k127_2220377_5 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 436.0
HKD1_k127_2220377_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 429.0
HKD1_k127_2220377_7 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 410.0
HKD1_k127_2220377_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 386.0
HKD1_k127_2220377_9 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 359.0
HKD1_k127_2239275_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 489.0
HKD1_k127_2239275_1 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 334.0
HKD1_k127_2239275_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000006729 62.0
HKD1_k127_2239275_11 TIGRFAM F0F1-ATPase subunit K02116 - - 0.0001579 50.0
HKD1_k127_2239275_2 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000003686 268.0
HKD1_k127_2239275_3 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007677 271.0
HKD1_k127_2239275_4 response to copper ion K02388,K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005374 254.0
HKD1_k127_2239275_5 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006832 227.0
HKD1_k127_2239275_6 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000306 203.0
HKD1_k127_2239275_7 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000001617 175.0
HKD1_k127_2239275_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000009523 148.0
HKD1_k127_2239275_9 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000000281 133.0
HKD1_k127_2296606_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 541.0
HKD1_k127_2296606_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 456.0
HKD1_k127_2296606_10 Isochorismatase family - - - 0.00000000000000000005035 101.0
HKD1_k127_2296606_11 Ribbon-helix-helix protein, copG family - - - 0.0000004963 61.0
HKD1_k127_2296606_12 Transcriptional regulator K13633 - - 0.0001912 50.0
HKD1_k127_2296606_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 379.0
HKD1_k127_2296606_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 375.0
HKD1_k127_2296606_4 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007793 250.0
HKD1_k127_2296606_5 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000009742 230.0
HKD1_k127_2296606_6 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.0000000000000000000000000000000000000589 154.0
HKD1_k127_2296606_7 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000009346 151.0
HKD1_k127_2296606_9 lactoylglutathione lyase activity - - - 0.00000000000000000000003087 108.0
HKD1_k127_2369831_0 Sulfatase K01130 - 3.1.6.1 0.0 1416.0
HKD1_k127_2369831_1 Protein of unknown function (DUF3604) - - - 7.103e-313 976.0
HKD1_k127_2369831_10 HupE / UreJ protein - - - 0.000000000000000000000003486 119.0
HKD1_k127_2369831_11 Methylamine utilisation protein MauE - - - 0.0000000000000000000004027 104.0
HKD1_k127_2369831_12 Cytochrome c - - - 0.0000000000000000002596 99.0
HKD1_k127_2369831_13 Cytochrome c K12263 - - 0.0000000000000000004768 90.0
HKD1_k127_2369831_2 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 407.0
HKD1_k127_2369831_3 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 358.0
HKD1_k127_2369831_4 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000002578 244.0
HKD1_k127_2369831_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000004918 230.0
HKD1_k127_2369831_6 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000009287 244.0
HKD1_k127_2369831_7 Methylamine dehydrogenase light chain - - - 0.00000000000000000000000000000000000000000000000000000000009235 224.0
HKD1_k127_2369831_8 methylamine dehydrogenase accessory protein MauD - - - 0.00000000000000000000000000000000000000000000000000000001234 212.0
HKD1_k127_2369831_9 Transcriptional Regulator, AraC family - - - 0.000000000000000000000000000000008896 141.0
HKD1_k127_2391903_0 Superfamily II DNA RNA helicases, SNF2 family - - - 3.894e-278 877.0
HKD1_k127_2391903_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 472.0
HKD1_k127_2391903_10 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000003228 233.0
HKD1_k127_2391903_11 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000001402 205.0
HKD1_k127_2391903_12 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000008187 186.0
HKD1_k127_2391903_13 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000002206 154.0
HKD1_k127_2391903_14 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000008451 125.0
HKD1_k127_2391903_15 MlaD protein K02067 - - 0.0000000000000000000000000005277 128.0
HKD1_k127_2391903_16 Transglycosylase SLT domain K08309 - - 0.000000000000000000007557 103.0
HKD1_k127_2391903_17 PFAM toluene tolerance family protein K07323 - - 0.0000000000001236 80.0
HKD1_k127_2391903_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
HKD1_k127_2391903_3 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 363.0
HKD1_k127_2391903_4 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 355.0
HKD1_k127_2391903_5 PFAM cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 334.0
HKD1_k127_2391903_6 DEAD_2 K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 342.0
HKD1_k127_2391903_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 304.0
HKD1_k127_2391903_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000152 259.0
HKD1_k127_2391903_9 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000005528 225.0
HKD1_k127_243277_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 311.0
HKD1_k127_243277_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 308.0
HKD1_k127_243277_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000003654 111.0
HKD1_k127_243277_11 Belongs to the 'phage' integrase family - - - 0.0000000000000009831 88.0
HKD1_k127_243277_12 Pfam SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001665 74.0
HKD1_k127_243277_13 Matrixin - - - 0.0000000002174 74.0
HKD1_k127_243277_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 306.0
HKD1_k127_243277_3 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000003508 268.0
HKD1_k127_243277_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000001047 254.0
HKD1_k127_243277_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000007124 179.0
HKD1_k127_243277_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000001325 168.0
HKD1_k127_243277_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000004615 160.0
HKD1_k127_243277_8 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000247 138.0
HKD1_k127_243277_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000002289 117.0
HKD1_k127_2441796_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 617.0
HKD1_k127_2441796_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 417.0
HKD1_k127_2441796_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006133 241.0
HKD1_k127_2441796_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000003477 117.0
HKD1_k127_2441796_4 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 0.000000000000000038 95.0
HKD1_k127_245134_0 Sulfatase - - - 4.493e-245 764.0
HKD1_k127_245134_1 COG1055 Na H antiporter NhaD and related arsenite - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 568.0
HKD1_k127_245134_10 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000002559 213.0
HKD1_k127_245134_11 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000002627 201.0
HKD1_k127_245134_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000009069 189.0
HKD1_k127_245134_13 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000002493 169.0
HKD1_k127_245134_14 Multicopper oxidase K04753 - - 0.000000000000000000000000000000000000000481 171.0
HKD1_k127_245134_15 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000009348 151.0
HKD1_k127_245134_16 Heme iron utilization protein K07226 - - 0.00000000000000000000000000000000009911 154.0
HKD1_k127_245134_17 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000004631 142.0
HKD1_k127_245134_18 - - - - 0.00000000000000000007828 96.0
HKD1_k127_245134_19 It is involved in the biological process described with response to stress - GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008047,GO:0008150,GO:0009987,GO:0030234,GO:0031072,GO:0032781,GO:0043085,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051087,GO:0051336,GO:0051345,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000001756 95.0
HKD1_k127_245134_2 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 475.0
HKD1_k127_245134_20 Protein of unknown function (DUF1329) - - - 0.000000000000000005055 100.0
HKD1_k127_245134_21 SnoaL-like polyketide cyclase K06893 - - 0.0000000000002203 80.0
HKD1_k127_245134_22 Periplasmic binding protein - - - 0.0000004161 60.0
HKD1_k127_245134_24 Antibiotic biosynthesis monooxygenase - - - 0.0005784 51.0
HKD1_k127_245134_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 414.0
HKD1_k127_245134_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 365.0
HKD1_k127_245134_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 345.0
HKD1_k127_245134_6 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002167 273.0
HKD1_k127_245134_7 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000461 245.0
HKD1_k127_245134_8 BAAT / Acyl-CoA thioester hydrolase C terminal K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000001779 233.0
HKD1_k127_245134_9 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000001793 208.0
HKD1_k127_245691_0 May be the GTPase, regulating ATP sulfurylase activity K00955 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237 2.7.1.25,2.7.7.4 2.277e-245 789.0
HKD1_k127_245691_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 553.0
HKD1_k127_245691_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 323.0
HKD1_k127_245691_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000006182 231.0
HKD1_k127_245691_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000002227 224.0
HKD1_k127_245691_13 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000001287 210.0
HKD1_k127_245691_14 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000002554 229.0
HKD1_k127_245691_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000008016 210.0
HKD1_k127_245691_16 phosphatidylcholine synthase K01004 - 2.7.8.24 0.00000000000000000000000000000000000000000000004746 186.0
HKD1_k127_245691_17 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000004267 146.0
HKD1_k127_245691_18 TIGRFAM 2-oxoglutarate dehydrogenase, E2 component K00658 - 2.3.1.61 0.000000000000000000000002956 106.0
HKD1_k127_245691_19 MAPEG family - - - 0.0000000000007279 76.0
HKD1_k127_245691_2 Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 526.0
HKD1_k127_245691_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.00008109 53.0
HKD1_k127_245691_3 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 494.0
HKD1_k127_245691_4 Molybdenum Cofactor Synthesis C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 426.0
HKD1_k127_245691_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 434.0
HKD1_k127_245691_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 387.0
HKD1_k127_245691_7 enoyl-CoA hydratase isomerase family K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 397.0
HKD1_k127_245691_8 COG2084 3-hydroxyisobutyrate dehydrogenase and related K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 343.0
HKD1_k127_245691_9 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 334.0
HKD1_k127_2489180_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.352e-302 947.0
HKD1_k127_2489180_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000001136 85.0
HKD1_k127_2489180_2 Major Facilitator Superfamily K02445 GO:0005575,GO:0005576 - 0.0001128 54.0
HKD1_k127_2489284_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.111e-221 692.0
HKD1_k127_2489284_1 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 6.357e-206 653.0
HKD1_k127_2489284_10 Tetratricopeptide repeat - - - 0.0001525 55.0
HKD1_k127_2489284_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 499.0
HKD1_k127_2489284_3 endo-1,4-beta-xylanase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 409.0
HKD1_k127_2489284_4 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 353.0
HKD1_k127_2489284_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 317.0
HKD1_k127_2489284_6 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000166 292.0
HKD1_k127_2489284_7 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000722 223.0
HKD1_k127_2489284_9 Amino acid permease K03757,K03759 - - 0.000001085 59.0
HKD1_k127_2507760_0 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 447.0
HKD1_k127_2507760_1 desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 313.0
HKD1_k127_2507760_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000925 237.0
HKD1_k127_2507760_3 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000001579 236.0
HKD1_k127_2507760_4 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0005799 53.0
HKD1_k127_2526689_0 Carbon starvation protein CstA K06200 - - 1.357e-269 861.0
HKD1_k127_2526689_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 552.0
HKD1_k127_2526689_10 amp-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 339.0
HKD1_k127_2526689_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 287.0
HKD1_k127_2526689_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001149 266.0
HKD1_k127_2526689_13 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000001255 254.0
HKD1_k127_2526689_14 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001636 237.0
HKD1_k127_2526689_16 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000009551 225.0
HKD1_k127_2526689_17 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000003914 190.0
HKD1_k127_2526689_18 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000559 194.0
HKD1_k127_2526689_19 Peptidase family M48 - - - 0.000000000000000000000000000000000000000006326 171.0
HKD1_k127_2526689_2 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 540.0
HKD1_k127_2526689_20 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.00000000000000000000000000000000000000001041 170.0
HKD1_k127_2526689_21 transport system, permease component K01992 - - 0.00000000000000000000000000000003923 136.0
HKD1_k127_2526689_22 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000001375 123.0
HKD1_k127_2526689_23 acyl carrier protein K02078 - - 0.0000000000000000000000167 102.0
HKD1_k127_2526689_24 Membrane - - - 0.0000000000001971 81.0
HKD1_k127_2526689_25 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000004941 80.0
HKD1_k127_2526689_26 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000001762 68.0
HKD1_k127_2526689_27 Dehydratase - - - 0.0000000002558 73.0
HKD1_k127_2526689_28 - - - - 0.00000005052 67.0
HKD1_k127_2526689_3 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 509.0
HKD1_k127_2526689_30 Phosphopantetheine attachment site - - - 0.0000006038 58.0
HKD1_k127_2526689_31 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00001726 51.0
HKD1_k127_2526689_32 exo-alpha-(2->6)-sialidase activity K00368,K07004,K20276 - 1.7.2.1 0.0002263 53.0
HKD1_k127_2526689_4 PFAM phenylalanine histidine ammonia-lyase K01745,K10774 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009698,GO:0009699,GO:0009987,GO:0016043,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052883,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.23,4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 474.0
HKD1_k127_2526689_5 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 392.0
HKD1_k127_2526689_6 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 354.0
HKD1_k127_2526689_7 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 360.0
HKD1_k127_2526689_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 336.0
HKD1_k127_2526689_9 Tryptophan halogenase K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 330.0
HKD1_k127_2612611_0 glutamate synthase, alpha subunit domain protein K00284 - 1.4.7.1 0.0 1776.0
HKD1_k127_2612611_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.888e-213 698.0
HKD1_k127_2612611_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 300.0
HKD1_k127_2612611_11 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 308.0
HKD1_k127_2612611_12 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000394 234.0
HKD1_k127_2612611_13 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000003761 213.0
HKD1_k127_2612611_14 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006587 216.0
HKD1_k127_2612611_15 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000001267 180.0
HKD1_k127_2612611_16 transporter component K07112 - - 0.00000000000000000000000000000000000000000004647 173.0
HKD1_k127_2612611_17 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000002106 146.0
HKD1_k127_2612611_19 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000804 128.0
HKD1_k127_2612611_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 626.0
HKD1_k127_2612611_20 transporter component K07112 - - 0.000000000000000000000001265 118.0
HKD1_k127_2612611_21 Rhodanese Homology Domain - - - 0.00000000000000000003891 97.0
HKD1_k127_2612611_22 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000001046 90.0
HKD1_k127_2612611_23 - - - - 0.0000000000003568 70.0
HKD1_k127_2612611_24 Bacterial regulatory proteins, tetR family - - - 0.0000000000004512 77.0
HKD1_k127_2612611_25 Cell division protein ZapA K09888 - - 0.0003014 47.0
HKD1_k127_2612611_3 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 639.0
HKD1_k127_2612611_4 (ABC) transporter K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 446.0
HKD1_k127_2612611_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 415.0
HKD1_k127_2612611_6 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 405.0
HKD1_k127_2612611_7 ABC-type multidrug transport system ATPase and permease K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 411.0
HKD1_k127_2612611_8 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 391.0
HKD1_k127_2612611_9 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 315.0
HKD1_k127_2774817_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1268.0
HKD1_k127_2774817_1 Flavin-binding monooxygenase-like - - - 4.196e-257 801.0
HKD1_k127_2774817_10 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000001335 164.0
HKD1_k127_2774817_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000001415 171.0
HKD1_k127_2774817_12 PFAM MAPEG family - - - 0.00000000000000000000000000000000000000001096 157.0
HKD1_k127_2774817_13 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000998 156.0
HKD1_k127_2774817_14 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.00000000000000000000000000000000003184 140.0
HKD1_k127_2774817_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000000000000003695 127.0
HKD1_k127_2774817_17 Phenazine biosynthesis protein A/B K06893 - - 0.00000000005233 70.0
HKD1_k127_2774817_18 Protein of unknown function, DUF393 - - - 0.0000218 56.0
HKD1_k127_2774817_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 525.0
HKD1_k127_2774817_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 511.0
HKD1_k127_2774817_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 438.0
HKD1_k127_2774817_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 301.0
HKD1_k127_2774817_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000048 245.0
HKD1_k127_2774817_7 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000008179 201.0
HKD1_k127_2774817_8 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000000003109 194.0
HKD1_k127_2774817_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000001408 176.0
HKD1_k127_2811960_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 426.0
HKD1_k127_2811960_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 396.0
HKD1_k127_2811960_2 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000001426 232.0
HKD1_k127_2811960_3 U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.00000000000000005009 87.0
HKD1_k127_2811960_4 Sterol carrier protein - - - 0.00003223 51.0
HKD1_k127_2834798_0 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 393.0
HKD1_k127_2834798_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 352.0
HKD1_k127_2834798_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000001861 232.0
HKD1_k127_2834798_3 PFAM DUF218 domain - - - 0.000000000000000000000000000000000000001502 165.0
HKD1_k127_2834798_4 Bacterial SH3 domain - - - 0.0008092 49.0
HKD1_k127_2863005_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 588.0
HKD1_k127_2863005_1 RNA polymerase recycling family C-terminal K03580 - - 0.00000000000000000000000000000000005814 147.0
HKD1_k127_2863005_2 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.00000000001316 72.0
HKD1_k127_2876098_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.418e-299 945.0
HKD1_k127_2876098_1 Insecticidal toxin complex protein TcaC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 665.0
HKD1_k127_2876098_10 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005615 272.0
HKD1_k127_2876098_11 peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000007181 212.0
HKD1_k127_2876098_12 PFAM DinB family protein - - - 0.00000000000000000000000000000000000000000000000000000589 195.0
HKD1_k127_2876098_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000002864 194.0
HKD1_k127_2876098_14 - - - - 0.0000000000000000000000000000000000000000000000000004177 206.0
HKD1_k127_2876098_15 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000001201 186.0
HKD1_k127_2876098_16 Alpha beta hydrolase K01066 - - 0.00000000000000000000000000000000000000000003626 176.0
HKD1_k127_2876098_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000002831 174.0
HKD1_k127_2876098_18 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000373 148.0
HKD1_k127_2876098_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000001733 152.0
HKD1_k127_2876098_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 543.0
HKD1_k127_2876098_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000004461 136.0
HKD1_k127_2876098_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000005944 134.0
HKD1_k127_2876098_22 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000182 127.0
HKD1_k127_2876098_23 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000006593 111.0
HKD1_k127_2876098_24 Protein of unknown function, DUF393 - - - 0.00000000000000000000000006805 117.0
HKD1_k127_2876098_25 haemagglutination activity domain - - - 0.0000000000000000000000000906 128.0
HKD1_k127_2876098_26 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000002534 113.0
HKD1_k127_2876098_27 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000004098 110.0
HKD1_k127_2876098_28 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000001347 91.0
HKD1_k127_2876098_29 Ornithine cyclodeaminase/mu-crystallin family K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.00000000009795 75.0
HKD1_k127_2876098_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 481.0
HKD1_k127_2876098_30 self proteolysis - - - 0.00000007208 68.0
HKD1_k127_2876098_31 capsule polysaccharide biosynthetic process K13687 GO:0008150,GO:0040007 - 0.00002874 57.0
HKD1_k127_2876098_32 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0001001 55.0
HKD1_k127_2876098_4 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 441.0
HKD1_k127_2876098_5 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 437.0
HKD1_k127_2876098_6 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 396.0
HKD1_k127_2876098_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 379.0
HKD1_k127_2876098_8 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 346.0
HKD1_k127_2876098_9 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 295.0
HKD1_k127_288934_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 536.0
HKD1_k127_288934_1 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 384.0
HKD1_k127_288934_10 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000006607 162.0
HKD1_k127_288934_11 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K00773,K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29,2.4.99.17 0.000000000000000000000000000004878 138.0
HKD1_k127_288934_12 amine dehydrogenase activity K00504,K12132 - 1.14.17.3,2.7.11.1 0.000000000000000000000013 113.0
HKD1_k127_288934_13 FHA domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000000001256 74.0
HKD1_k127_288934_15 Protein of unknown function (FYDLN_acid) - - - 0.00000000003768 68.0
HKD1_k127_288934_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 375.0
HKD1_k127_288934_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 353.0
HKD1_k127_288934_4 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000004134 271.0
HKD1_k127_288934_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000002913 256.0
HKD1_k127_288934_6 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008682 260.0
HKD1_k127_288934_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000002013 252.0
HKD1_k127_288934_8 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000002937 210.0
HKD1_k127_288934_9 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000005219 204.0
HKD1_k127_2945679_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.169e-285 895.0
HKD1_k127_2945679_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 2.977e-221 717.0
HKD1_k127_2945679_10 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 400.0
HKD1_k127_2945679_11 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 370.0
HKD1_k127_2945679_12 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 355.0
HKD1_k127_2945679_13 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 323.0
HKD1_k127_2945679_14 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 316.0
HKD1_k127_2945679_15 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 307.0
HKD1_k127_2945679_16 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000003466 264.0
HKD1_k127_2945679_17 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000004281 271.0
HKD1_k127_2945679_18 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006775 271.0
HKD1_k127_2945679_19 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000001426 259.0
HKD1_k127_2945679_2 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 571.0
HKD1_k127_2945679_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009736 243.0
HKD1_k127_2945679_21 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000001917 254.0
HKD1_k127_2945679_22 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000003247 234.0
HKD1_k127_2945679_23 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000007099 244.0
HKD1_k127_2945679_24 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000318 218.0
HKD1_k127_2945679_25 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000006187 234.0
HKD1_k127_2945679_26 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000004044 226.0
HKD1_k127_2945679_27 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000421 225.0
HKD1_k127_2945679_28 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000001582 194.0
HKD1_k127_2945679_29 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000002414 194.0
HKD1_k127_2945679_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 554.0
HKD1_k127_2945679_30 - - - - 0.0000000000000000000000000000000000000000000009874 190.0
HKD1_k127_2945679_31 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000555 189.0
HKD1_k127_2945679_32 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000001792 149.0
HKD1_k127_2945679_33 transcriptional regulator - - - 0.000000000000000000000000000005656 127.0
HKD1_k127_2945679_34 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000002422 117.0
HKD1_k127_2945679_35 PFAM PHA accumulation regulator DNA-binding protein - - - 0.000000000000000000000002603 109.0
HKD1_k127_2945679_36 EXOIII K02342 - 2.7.7.7 0.000000000000000000000006109 117.0
HKD1_k127_2945679_37 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000005221 102.0
HKD1_k127_2945679_38 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000006576 89.0
HKD1_k127_2945679_39 PFAM FeoA family protein K04758 - - 0.00000000006735 67.0
HKD1_k127_2945679_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 527.0
HKD1_k127_2945679_40 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016627,GO:0016635,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 - 0.0000000007955 69.0
HKD1_k127_2945679_41 Domain of unknown function (DUF1956) - - - 0.000000001777 67.0
HKD1_k127_2945679_42 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.000002143 61.0
HKD1_k127_2945679_43 - - - - 0.000008192 54.0
HKD1_k127_2945679_44 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00003914 56.0
HKD1_k127_2945679_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 516.0
HKD1_k127_2945679_6 acyl-CoA transferases carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 477.0
HKD1_k127_2945679_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 439.0
HKD1_k127_2945679_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 410.0
HKD1_k127_2945679_9 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 399.0
HKD1_k127_2951001_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 473.0
HKD1_k127_2951001_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009885 280.0
HKD1_k127_2951001_2 - - - - 0.00000000000000000000000000000000000000000000004362 176.0
HKD1_k127_2951001_3 PFAM YD repeat-containing protein - - - 0.0000000009277 68.0
HKD1_k127_2955434_0 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123 - 1.17.1.9 3.597e-238 772.0
HKD1_k127_2955434_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.442e-198 631.0
HKD1_k127_2955434_10 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 344.0
HKD1_k127_2955434_11 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 342.0
HKD1_k127_2955434_12 COG0348 Polyferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 314.0
HKD1_k127_2955434_13 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009444 282.0
HKD1_k127_2955434_14 Acyl-CoA synthetase (NDP forming) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007286 271.0
HKD1_k127_2955434_15 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007776 257.0
HKD1_k127_2955434_16 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000215 235.0
HKD1_k127_2955434_17 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000128 235.0
HKD1_k127_2955434_18 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000006849 227.0
HKD1_k127_2955434_19 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000246 210.0
HKD1_k127_2955434_2 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 500.0
HKD1_k127_2955434_20 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000005475 183.0
HKD1_k127_2955434_21 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000002565 168.0
HKD1_k127_2955434_22 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000005818 166.0
HKD1_k127_2955434_23 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000001002 151.0
HKD1_k127_2955434_24 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000008118 157.0
HKD1_k127_2955434_25 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000003128 142.0
HKD1_k127_2955434_26 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000003289 125.0
HKD1_k127_2955434_27 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000498 112.0
HKD1_k127_2955434_28 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000005854 107.0
HKD1_k127_2955434_29 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.0000000000000000000000157 114.0
HKD1_k127_2955434_3 phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 521.0
HKD1_k127_2955434_30 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000002397 110.0
HKD1_k127_2955434_31 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000002721 104.0
HKD1_k127_2955434_32 Bacterial regulatory protein, Fis family K07714 - - 0.0000000000000002135 85.0
HKD1_k127_2955434_33 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000007146 91.0
HKD1_k127_2955434_34 Universal stress protein family - - - 0.00000000369 69.0
HKD1_k127_2955434_35 Prokaryotic dksA traR C4-type zinc finger - - - 0.00000005351 66.0
HKD1_k127_2955434_36 - - - - 0.0000005872 55.0
HKD1_k127_2955434_38 FixH - - - 0.0006995 49.0
HKD1_k127_2955434_4 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 483.0
HKD1_k127_2955434_5 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 402.0
HKD1_k127_2955434_6 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 403.0
HKD1_k127_2955434_7 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 408.0
HKD1_k127_2955434_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 364.0
HKD1_k127_2955434_9 NADH dehydrogenase K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 345.0
HKD1_k127_3043228_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 407.0
HKD1_k127_3043228_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000000000000000000000000000001685 207.0
HKD1_k127_3043228_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000001619 187.0
HKD1_k127_3043228_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000001569 112.0
HKD1_k127_3043228_4 high-affinity sulfate:proton symporter activity K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.00000000000000000005857 104.0
HKD1_k127_3043228_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000258 77.0
HKD1_k127_3043228_6 Protein of unknown function (DUF3426) - - - 0.00000224 61.0
HKD1_k127_3142282_0 Molydopterin dinucleotide binding domain - - - 6.089e-280 890.0
HKD1_k127_3142282_1 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 612.0
HKD1_k127_3142282_10 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000476 271.0
HKD1_k127_3142282_11 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000005863 271.0
HKD1_k127_3142282_12 MreB/Mbl protein K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001793 265.0
HKD1_k127_3142282_13 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004177 249.0
HKD1_k127_3142282_14 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000018 232.0
HKD1_k127_3142282_15 pyridoxamine 5-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
HKD1_k127_3142282_16 Psort location Cytoplasmic, score 8.87 K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000001781 240.0
HKD1_k127_3142282_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000003101 196.0
HKD1_k127_3142282_18 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000004378 186.0
HKD1_k127_3142282_19 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000001659 160.0
HKD1_k127_3142282_2 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 597.0
HKD1_k127_3142282_20 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000003421 159.0
HKD1_k127_3142282_21 - - - - 0.00000000000000000000000000000001808 136.0
HKD1_k127_3142282_22 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000005225 131.0
HKD1_k127_3142282_23 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000003834 123.0
HKD1_k127_3142282_24 Belongs to the universal stress protein A family - - - 0.00000000000000000000000009811 117.0
HKD1_k127_3142282_25 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000001248 102.0
HKD1_k127_3142282_26 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000004105 97.0
HKD1_k127_3142282_27 Putative zinc-finger - - - 0.00000000000000004518 87.0
HKD1_k127_3142282_28 CHAP domain - - - 0.00000000000009225 79.0
HKD1_k127_3142282_29 - - - - 0.0000000006339 71.0
HKD1_k127_3142282_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 483.0
HKD1_k127_3142282_4 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 422.0
HKD1_k127_3142282_5 lysyl-tRNA synthetase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 409.0
HKD1_k127_3142282_6 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 401.0
HKD1_k127_3142282_7 Enoyl-CoA hydratase/isomerase K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 358.0
HKD1_k127_3142282_8 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 334.0
HKD1_k127_3142282_9 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 308.0
HKD1_k127_3162868_0 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 383.0
HKD1_k127_3162868_1 Ferric reductase NAD binding domain K02613,K15983 - 1.14.13.142 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 338.0
HKD1_k127_3162868_2 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.0000000000000000000000000000000000000000000000000006747 193.0
HKD1_k127_3162868_3 - - - - 0.00000000000000000000000000000000001517 151.0
HKD1_k127_317651_0 glutamate catabolic process to 2-oxoglutarate K15371 - 1.4.1.2 6.505e-240 788.0
HKD1_k127_317651_1 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 323.0
HKD1_k127_317651_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000001305 229.0
HKD1_k127_317651_3 Transcriptional regulator K02624,K13641 - - 0.00000000000000000000000000000000000000000001401 171.0
HKD1_k127_317651_4 Acetyltransferase (isoleucine patch K00661 - 2.3.1.79 0.000000000000004205 86.0
HKD1_k127_317651_5 COG1145 Ferredoxin - - - 0.00000004005 59.0
HKD1_k127_317651_6 COG1145 Ferredoxin - - - 0.00008195 55.0
HKD1_k127_3202949_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 5.338e-299 951.0
HKD1_k127_3202949_1 PFAM Prenyltransferase and squalene oxidase repeat K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 623.0
HKD1_k127_3202949_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000007675 220.0
HKD1_k127_3202949_11 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000001688 220.0
HKD1_k127_3202949_12 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000002389 206.0
HKD1_k127_3202949_13 4-amino-4-deoxy-L-arabinose transferase activity K07264 - 2.4.2.43 0.00000000000000000000000000000000000000000000002494 192.0
HKD1_k127_3202949_14 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000001163 183.0
HKD1_k127_3202949_15 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.00000000000000000000000000000000000000101 165.0
HKD1_k127_3202949_16 SnoaL-like domain - - - 0.0000000000000000000000000000000006967 134.0
HKD1_k127_3202949_17 photosynthesis - - - 0.000000000000000000000000000000001182 140.0
HKD1_k127_3202949_18 - - - - 0.000000000000000000000000009719 122.0
HKD1_k127_3202949_19 glutamate catabolic process to 2-oxoglutarate K15371 - 1.4.1.2 0.000000000000000000002365 106.0
HKD1_k127_3202949_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 560.0
HKD1_k127_3202949_20 long-chain fatty acid transport protein - - - 0.0000000000000000004055 98.0
HKD1_k127_3202949_21 - - - - 0.00000000000004215 87.0
HKD1_k127_3202949_22 IucA IucC family - - - 0.0000000000121 77.0
HKD1_k127_3202949_23 - - - - 0.00000000001887 77.0
HKD1_k127_3202949_24 Domain of Unknown Function (DUF748) - - - 0.00000000003012 78.0
HKD1_k127_3202949_25 BetI-type transcriptional repressor, C-terminal - - - 0.0000000001779 70.0
HKD1_k127_3202949_28 COG1977 Molybdopterin converting factor, small subunit K03636 - - 0.00005115 53.0
HKD1_k127_3202949_3 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 463.0
HKD1_k127_3202949_4 squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 440.0
HKD1_k127_3202949_5 PFAM S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 376.0
HKD1_k127_3202949_6 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 335.0
HKD1_k127_3202949_7 Xanthine dehydrogenase K13479,K16878 GO:0000166,GO:0003674,GO:0003824,GO:0004854,GO:0005488,GO:0006139,GO:0006144,GO:0006145,GO:0006150,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009114,GO:0009987,GO:0016491,GO:0016725,GO:0016726,GO:0019439,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046100,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071949,GO:0072521,GO:0072523,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.17.1.4,1.3.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 299.0
HKD1_k127_3202949_8 Squalene phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006267 282.0
HKD1_k127_3202949_9 2Fe-2S -binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000003657 265.0
HKD1_k127_3263556_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 5.179e-229 728.0
HKD1_k127_3263556_1 Acts as a magnesium transporter K06213 - - 2.086e-199 630.0
HKD1_k127_3263556_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 344.0
HKD1_k127_3263556_11 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 335.0
HKD1_k127_3263556_12 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 341.0
HKD1_k127_3263556_13 taurine catabolism dioxygenase K03119,K22303 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 318.0
HKD1_k127_3263556_14 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003004 257.0
HKD1_k127_3263556_15 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
HKD1_k127_3263556_16 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000002531 221.0
HKD1_k127_3263556_17 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00000000000000000000000000000000000000000000000033 195.0
HKD1_k127_3263556_18 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000003625 182.0
HKD1_k127_3263556_19 Methylmuconolactone methyl-isomerase - - - 0.000000000000000000000000000000000000000001518 159.0
HKD1_k127_3263556_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 571.0
HKD1_k127_3263556_20 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000000000000000000000000002444 168.0
HKD1_k127_3263556_21 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.00000000000000000000000000000000000000004669 170.0
HKD1_k127_3263556_22 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000000000000000000000007338 173.0
HKD1_k127_3263556_23 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000004447 164.0
HKD1_k127_3263556_24 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000004415 160.0
HKD1_k127_3263556_25 Domain of unknown function (DUF2341) K03561 - - 0.000000000000000000000000000002894 130.0
HKD1_k127_3263556_26 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000003351 125.0
HKD1_k127_3263556_27 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000006285 100.0
HKD1_k127_3263556_28 Transcriptional regulator - - - 0.000000000000000000001637 105.0
HKD1_k127_3263556_29 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000005775 104.0
HKD1_k127_3263556_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 564.0
HKD1_k127_3263556_30 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000001322 100.0
HKD1_k127_3263556_31 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.000000000000004511 88.0
HKD1_k127_3263556_32 Bacterial regulatory proteins, tetR family - - - 0.00000000000001021 83.0
HKD1_k127_3263556_33 Methylenetetrahydrofolate reductase K00297,K00544,K00547 - 1.5.1.20,2.1.1.10,2.1.1.5 0.0002929 53.0
HKD1_k127_3263556_34 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0003772 48.0
HKD1_k127_3263556_4 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 519.0
HKD1_k127_3263556_5 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 478.0
HKD1_k127_3263556_6 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 458.0
HKD1_k127_3263556_7 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 417.0
HKD1_k127_3263556_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 389.0
HKD1_k127_3263556_9 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 389.0
HKD1_k127_3271597_0 OmpA family - - - 0.0 1838.0
HKD1_k127_3271597_1 Domain of unknown function DUF11 - - - 0.0 1341.0
HKD1_k127_3271597_10 PFAM alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 355.0
HKD1_k127_3271597_11 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 344.0
HKD1_k127_3271597_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 355.0
HKD1_k127_3271597_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002129 289.0
HKD1_k127_3271597_14 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008056 258.0
HKD1_k127_3271597_15 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000001196 242.0
HKD1_k127_3271597_16 - - - - 0.0000000000000000000000000000000000000000000000000004843 189.0
HKD1_k127_3271597_17 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000853 191.0
HKD1_k127_3271597_18 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000002883 166.0
HKD1_k127_3271597_19 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000003474 159.0
HKD1_k127_3271597_2 Tetratricopeptide repeat - - - 1.979e-300 954.0
HKD1_k127_3271597_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000006716 163.0
HKD1_k127_3271597_21 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.00000000000000000000000000000000000002526 165.0
HKD1_k127_3271597_22 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000000008165 140.0
HKD1_k127_3271597_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000001328 140.0
HKD1_k127_3271597_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000001913 110.0
HKD1_k127_3271597_25 Large extracellular alpha-helical protein - - - 0.0000000000000000000001601 100.0
HKD1_k127_3271597_26 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000002003 106.0
HKD1_k127_3271597_27 - - - - 0.00000000000008147 82.0
HKD1_k127_3271597_28 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000001536 61.0
HKD1_k127_3271597_3 Tetratricopeptide repeat - - - 1.722e-204 653.0
HKD1_k127_3271597_4 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 541.0
HKD1_k127_3271597_5 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 531.0
HKD1_k127_3271597_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 494.0
HKD1_k127_3271597_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 453.0
HKD1_k127_3271597_8 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 425.0
HKD1_k127_3271597_9 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 371.0
HKD1_k127_3328916_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 532.0
HKD1_k127_3328916_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 412.0
HKD1_k127_3328916_10 Protein of unknown function (DUF2905) - - - 0.000000000007651 78.0
HKD1_k127_3328916_2 Glycosyltransferase family 28 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 335.0
HKD1_k127_3328916_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 319.0
HKD1_k127_3328916_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000398 256.0
HKD1_k127_3328916_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000241 226.0
HKD1_k127_3328916_6 - - - - 0.0000000000000000000000000002164 131.0
HKD1_k127_3328916_7 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000000000001536 116.0
HKD1_k127_3328916_8 - - - - 0.000000000000006016 88.0
HKD1_k127_3328916_9 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000000005434 79.0
HKD1_k127_3333198_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.198e-203 653.0
HKD1_k127_3333198_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 555.0
HKD1_k127_3333198_10 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 338.0
HKD1_k127_3333198_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 341.0
HKD1_k127_3333198_12 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 346.0
HKD1_k127_3333198_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 355.0
HKD1_k127_3333198_14 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 335.0
HKD1_k127_3333198_15 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 323.0
HKD1_k127_3333198_16 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 308.0
HKD1_k127_3333198_17 PFAM cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 329.0
HKD1_k127_3333198_18 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 296.0
HKD1_k127_3333198_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002008 298.0
HKD1_k127_3333198_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K15232 - 6.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 509.0
HKD1_k127_3333198_20 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002531 277.0
HKD1_k127_3333198_21 TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000002503 226.0
HKD1_k127_3333198_22 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000001405 231.0
HKD1_k127_3333198_23 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000001165 213.0
HKD1_k127_3333198_24 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000003833 222.0
HKD1_k127_3333198_25 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000004743 221.0
HKD1_k127_3333198_26 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000005161 212.0
HKD1_k127_3333198_27 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000001419 211.0
HKD1_k127_3333198_28 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000001372 206.0
HKD1_k127_3333198_29 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000002727 209.0
HKD1_k127_3333198_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 491.0
HKD1_k127_3333198_30 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000003233 219.0
HKD1_k127_3333198_31 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000002153 195.0
HKD1_k127_3333198_32 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000179 205.0
HKD1_k127_3333198_33 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000009207 198.0
HKD1_k127_3333198_34 Serine aminopeptidase, S33 K16434 - - 0.00000000000000000000000000000000000000000000003837 180.0
HKD1_k127_3333198_35 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000129 142.0
HKD1_k127_3333198_36 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000006171 124.0
HKD1_k127_3333198_37 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000005261 98.0
HKD1_k127_3333198_38 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000002189 88.0
HKD1_k127_3333198_4 oxidoreductases (related to aryl-alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 433.0
HKD1_k127_3333198_40 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000006936 95.0
HKD1_k127_3333198_41 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000001798 93.0
HKD1_k127_3333198_42 Histidine kinase K07647 - 2.7.13.3 0.000000000000005088 79.0
HKD1_k127_3333198_43 inositol 2-dehydrogenase activity - - - 0.00000000000002849 84.0
HKD1_k127_3333198_44 cheY-homologous receiver domain K02657 - - 0.0000000000000721 85.0
HKD1_k127_3333198_45 Putative DNA-binding domain - - - 0.000000000000111 74.0
HKD1_k127_3333198_48 - - - - 0.000000000007607 74.0
HKD1_k127_3333198_49 AsmA family K07289 - - 0.0000000000157 78.0
HKD1_k127_3333198_5 Succinyl-CoA ligase like flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 426.0
HKD1_k127_3333198_50 Neisseria PilC beta-propeller domain K02674 - - 0.00000000008688 73.0
HKD1_k127_3333198_51 response regulator receiver - - - 0.0000008409 59.0
HKD1_k127_3333198_52 Thioesterase superfamily - - - 0.0000938 52.0
HKD1_k127_3333198_53 Protein of unknown function (DUF1329) - - - 0.000772 53.0
HKD1_k127_3333198_6 D-arabinono-1,4-lactone oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 409.0
HKD1_k127_3333198_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 411.0
HKD1_k127_3333198_8 Belongs to the DEAD box helicase family K03732,K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 372.0
HKD1_k127_3333198_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 379.0
HKD1_k127_3352242_0 PFAM Type II secretion system protein E K02652 - - 1.444e-243 766.0
HKD1_k127_3352242_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 583.0
HKD1_k127_3352242_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 320.0
HKD1_k127_3352242_11 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 321.0
HKD1_k127_3352242_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002373 288.0
HKD1_k127_3352242_13 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009084 289.0
HKD1_k127_3352242_14 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001252 283.0
HKD1_k127_3352242_15 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000765 284.0
HKD1_k127_3352242_16 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001379 262.0
HKD1_k127_3352242_17 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000001373 257.0
HKD1_k127_3352242_18 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000003322 226.0
HKD1_k127_3352242_19 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000001274 235.0
HKD1_k127_3352242_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 485.0
HKD1_k127_3352242_20 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000001698 237.0
HKD1_k127_3352242_21 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000238 228.0
HKD1_k127_3352242_22 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000002675 194.0
HKD1_k127_3352242_23 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000007167 199.0
HKD1_k127_3352242_24 - - - - 0.00000000000000000000000000000000000000000000003559 192.0
HKD1_k127_3352242_25 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000003885 178.0
HKD1_k127_3352242_26 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000002361 184.0
HKD1_k127_3352242_27 N2,N2-dimethylguanosine tRNA methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000003717 149.0
HKD1_k127_3352242_28 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000003757 151.0
HKD1_k127_3352242_29 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000392 136.0
HKD1_k127_3352242_3 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 494.0
HKD1_k127_3352242_30 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000003501 129.0
HKD1_k127_3352242_31 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000005336 114.0
HKD1_k127_3352242_32 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000001394 117.0
HKD1_k127_3352242_33 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000001145 111.0
HKD1_k127_3352242_34 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000001251 109.0
HKD1_k127_3352242_35 Tetratricopeptide repeat - - - 0.00000000000000000000006246 109.0
HKD1_k127_3352242_36 alginic acid biosynthetic process - - - 0.000000000000000000001079 109.0
HKD1_k127_3352242_37 Pfam:N_methyl_2 K02650 - - 0.000000000000000000005295 101.0
HKD1_k127_3352242_38 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000002001 85.0
HKD1_k127_3352242_39 Pilus assembly protein, PilP K02665 - - 0.0000000000000005548 85.0
HKD1_k127_3352242_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 479.0
HKD1_k127_3352242_40 Roadblock/LC7 domain - - - 0.000000000000003255 86.0
HKD1_k127_3352242_41 permease K11720 - - 0.000000001196 72.0
HKD1_k127_3352242_42 CI repressor - - - 0.0000355 51.0
HKD1_k127_3352242_5 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 417.0
HKD1_k127_3352242_6 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 395.0
HKD1_k127_3352242_7 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 412.0
HKD1_k127_3352242_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 369.0
HKD1_k127_3352242_9 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 336.0
HKD1_k127_3386918_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.407e-257 814.0
HKD1_k127_3386918_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.03e-249 785.0
HKD1_k127_3386918_10 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000008658 201.0
HKD1_k127_3386918_11 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000507 191.0
HKD1_k127_3386918_12 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000004194 159.0
HKD1_k127_3386918_13 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000002714 134.0
HKD1_k127_3386918_14 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000003057 132.0
HKD1_k127_3386918_15 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000005151 121.0
HKD1_k127_3386918_16 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000002716 100.0
HKD1_k127_3386918_17 guanyl-nucleotide exchange factor activity - - - 0.0000000002643 74.0
HKD1_k127_3386918_18 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000442 61.0
HKD1_k127_3386918_19 CheC-like family K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.000007819 59.0
HKD1_k127_3386918_2 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 298.0
HKD1_k127_3386918_20 Type IV pili signal transduction protein PilI K02659 - - 0.00001029 55.0
HKD1_k127_3386918_21 transcription factor (CBF NF-Y) - - - 0.00002705 49.0
HKD1_k127_3386918_22 metal-dependent phosphohydrolase, HD sub domain K13815 - - 0.0001221 56.0
HKD1_k127_3386918_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 303.0
HKD1_k127_3386918_4 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001337 264.0
HKD1_k127_3386918_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003921 263.0
HKD1_k127_3386918_6 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
HKD1_k127_3386918_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356,K03503 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000002477 218.0
HKD1_k127_3386918_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000008499 219.0
HKD1_k127_3386918_9 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000008939 228.0
HKD1_k127_3417816_0 glycolate oxidase subunit glcD K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 461.0
HKD1_k127_3417816_1 Short-chain dehydrogenase reductase sdr K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002888 264.0
HKD1_k127_3417816_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003382 256.0
HKD1_k127_3417816_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001119 161.0
HKD1_k127_3417816_4 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.0000000000000000000000000000000000009442 159.0
HKD1_k127_3417816_5 Cysteine-rich domain K11473 - - 0.000000000000000000000000000002956 126.0
HKD1_k127_3417816_6 C4-type zinc ribbon domain K07164 - - 0.000000000000001018 90.0
HKD1_k127_3588641_0 DEAD DEAH box helicase K06877 - - 1.496e-274 876.0
HKD1_k127_3588641_1 Heat shock 70 kDa protein K04043 - - 1.38e-273 855.0
HKD1_k127_3588641_10 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000005325 265.0
HKD1_k127_3588641_11 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000002164 210.0
HKD1_k127_3588641_12 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000002507 202.0
HKD1_k127_3588641_13 OmpA family K02557 - - 0.00000000000000000000000000000000001412 158.0
HKD1_k127_3588641_14 Flavin reductase like domain K00484,K16048 - 1.5.1.36 0.0000000000000000000000000000000000473 139.0
HKD1_k127_3588641_15 Transcriptional regulator - - - 0.0000000000000000000000000235 119.0
HKD1_k127_3588641_16 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000007007 105.0
HKD1_k127_3588641_17 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000001627 112.0
HKD1_k127_3588641_18 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000001386 89.0
HKD1_k127_3588641_19 Preprotein translocase SecG subunit K03075 - - 0.0000000000000001327 85.0
HKD1_k127_3588641_2 Found in ATP-dependent protease La (LON) K01338 - 3.4.21.53 3.193e-253 807.0
HKD1_k127_3588641_20 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000001618 83.0
HKD1_k127_3588641_21 Hsp20/alpha crystallin family K13993 - - 0.000000000009961 74.0
HKD1_k127_3588641_22 protein transport across the cell outer membrane K02457,K02672,K08084,K08085 - - 0.000009504 57.0
HKD1_k127_3588641_23 Cytochrome c-type protein K02569 - - 0.0005924 53.0
HKD1_k127_3588641_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 578.0
HKD1_k127_3588641_4 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 463.0
HKD1_k127_3588641_5 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 476.0
HKD1_k127_3588641_6 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 433.0
HKD1_k127_3588641_7 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 392.0
HKD1_k127_3588641_8 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 385.0
HKD1_k127_3588641_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001665 284.0
HKD1_k127_364210_0 Domain of unknown function (DUF4331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 596.0
HKD1_k127_364210_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 588.0
HKD1_k127_364210_10 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 339.0
HKD1_k127_364210_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000234 286.0
HKD1_k127_364210_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001305 259.0
HKD1_k127_364210_13 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
HKD1_k127_364210_14 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000001916 209.0
HKD1_k127_364210_2 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 559.0
HKD1_k127_364210_3 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 529.0
HKD1_k127_364210_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01115 - 3.1.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 513.0
HKD1_k127_364210_5 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 477.0
HKD1_k127_364210_6 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 476.0
HKD1_k127_364210_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 389.0
HKD1_k127_364210_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 349.0
HKD1_k127_364210_9 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 335.0
HKD1_k127_3725526_0 Amino acid permease K03294,K16238 - - 2.976e-199 650.0
HKD1_k127_3725526_1 elongation factor G domain IV K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 587.0
HKD1_k127_3725526_10 Protein phosphatase 2C K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000001412 188.0
HKD1_k127_3725526_11 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000097 191.0
HKD1_k127_3725526_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000002198 179.0
HKD1_k127_3725526_13 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000002256 151.0
HKD1_k127_3725526_14 PFAM GGDEF domain containing protein - - - 0.0000000000000000003995 103.0
HKD1_k127_3725526_15 Diguanylate cyclase - - - 0.00000000000001146 88.0
HKD1_k127_3725526_16 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 0.00000000007287 76.0
HKD1_k127_3725526_17 ANTAR - - - 0.000000247 64.0
HKD1_k127_3725526_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 437.0
HKD1_k127_3725526_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 412.0
HKD1_k127_3725526_4 Sigma-54 interaction domain K07713,K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 369.0
HKD1_k127_3725526_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 314.0
HKD1_k127_3725526_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000343 261.0
HKD1_k127_3725526_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000359 235.0
HKD1_k127_3725526_8 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000000000000004247 192.0
HKD1_k127_3725526_9 - - - - 0.00000000000000000000000000000000000000000000000001513 194.0
HKD1_k127_3727935_0 E1-E2 ATPase K01535 - 3.6.3.6 9.512e-291 919.0
HKD1_k127_3727935_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.967e-230 739.0
HKD1_k127_3727935_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 296.0
HKD1_k127_3727935_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000189 272.0
HKD1_k127_3727935_12 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000001144 243.0
HKD1_k127_3727935_13 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002429 259.0
HKD1_k127_3727935_14 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000001121 245.0
HKD1_k127_3727935_15 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000002607 241.0
HKD1_k127_3727935_16 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000001314 230.0
HKD1_k127_3727935_17 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000000000001022 210.0
HKD1_k127_3727935_18 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000009869 211.0
HKD1_k127_3727935_19 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000005458 196.0
HKD1_k127_3727935_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 494.0
HKD1_k127_3727935_20 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000003748 197.0
HKD1_k127_3727935_21 - - - - 0.000000000000000000000000000000000000000000000006295 185.0
HKD1_k127_3727935_22 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001047 176.0
HKD1_k127_3727935_23 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000208 171.0
HKD1_k127_3727935_24 methyltransferase - - - 0.00000000000000000000000000000000000000002259 160.0
HKD1_k127_3727935_25 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K01647,K22491 - 2.3.3.1 0.00000000000000000000000000000000000001011 156.0
HKD1_k127_3727935_26 SnoaL-like domain - - - 0.0000000000000000000000000000000000002825 144.0
HKD1_k127_3727935_27 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000006345 136.0
HKD1_k127_3727935_28 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000004198 130.0
HKD1_k127_3727935_29 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000539 143.0
HKD1_k127_3727935_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 452.0
HKD1_k127_3727935_30 - - - - 0.00000000000000000000000000000007091 143.0
HKD1_k127_3727935_31 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000003139 133.0
HKD1_k127_3727935_32 synthase K00574 - 2.1.1.79 0.00000000000000000000000000009302 128.0
HKD1_k127_3727935_33 YCII-related domain - - - 0.0000000000000000000000001492 124.0
HKD1_k127_3727935_34 YCII-related domain - - - 0.0000000000000000000004522 106.0
HKD1_k127_3727935_35 - - - - 0.00000000000000229 83.0
HKD1_k127_3727935_36 Glucose dehydrogenase K00117 GO:0000287,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008876,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0031224,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044425,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0048039,GO:0055114,GO:0070968,GO:0071944,GO:0097159,GO:1901363 1.1.5.2 0.00000000000006836 74.0
HKD1_k127_3727935_37 - - - - 0.000000000004551 79.0
HKD1_k127_3727935_38 - - - - 0.00000000001289 78.0
HKD1_k127_3727935_39 Copper binding proteins, plastocyanin/azurin family - - - 0.0008502 49.0
HKD1_k127_3727935_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 446.0
HKD1_k127_3727935_5 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006805,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0016491,GO:0016705,GO:0018690,GO:0020037,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071466,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 441.0
HKD1_k127_3727935_6 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 389.0
HKD1_k127_3727935_7 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 359.0
HKD1_k127_3727935_8 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 325.0
HKD1_k127_3727935_9 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 293.0
HKD1_k127_3732336_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1334.0
HKD1_k127_3732336_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 7.638e-317 1020.0
HKD1_k127_3732336_10 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001497 283.0
HKD1_k127_3732336_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002283 297.0
HKD1_k127_3732336_12 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003813 280.0
HKD1_k127_3732336_13 membrane-anchored protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002027 258.0
HKD1_k127_3732336_14 Rhodanese Homology Domain K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001653 256.0
HKD1_k127_3732336_15 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000000003236 254.0
HKD1_k127_3732336_16 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000002833 234.0
HKD1_k127_3732336_17 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000003714 252.0
HKD1_k127_3732336_18 PFAM Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000005113 218.0
HKD1_k127_3732336_19 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001541 216.0
HKD1_k127_3732336_2 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 1.438e-231 773.0
HKD1_k127_3732336_20 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000001173 215.0
HKD1_k127_3732336_21 lipoprotein localization to outer membrane K09808 - - 0.00000000000000000000000000000000000000000000000000000001352 224.0
HKD1_k127_3732336_22 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000001098 197.0
HKD1_k127_3732336_23 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000006099 188.0
HKD1_k127_3732336_24 Ham1 family K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000005987 175.0
HKD1_k127_3732336_25 NUDIX domain - - - 0.000000000000000000000000000000000000000007138 168.0
HKD1_k127_3732336_26 Von willebrand factor, type a - - - 0.000000000000000000000000000000000000001262 158.0
HKD1_k127_3732336_27 membrane - - - 0.00000000000000000000000000000000000001051 148.0
HKD1_k127_3732336_28 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000003053 166.0
HKD1_k127_3732336_29 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000000000000002833 144.0
HKD1_k127_3732336_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 502.0
HKD1_k127_3732336_30 heme oxygenase (decyclizing) activity K15969 - 1.13.12.21 0.00000000000000000000000000000001714 130.0
HKD1_k127_3732336_31 GIY-YIG type nucleases (URI domain) K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.0000000000000000000000000000001852 134.0
HKD1_k127_3732336_32 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.00000000000000000000002078 111.0
HKD1_k127_3732336_33 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000006319 106.0
HKD1_k127_3732336_34 - - - - 0.0000000000000000000003358 114.0
HKD1_k127_3732336_35 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000002082 85.0
HKD1_k127_3732336_36 Belongs to the 'phage' integrase family - - - 0.000000000001666 68.0
HKD1_k127_3732336_37 QacR-like protein, C-terminal region - - - 0.000000000001706 79.0
HKD1_k127_3732336_39 Periplasmic protein - - - 0.0000008233 60.0
HKD1_k127_3732336_4 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 488.0
HKD1_k127_3732336_40 - - - - 0.0001413 51.0
HKD1_k127_3732336_41 von Willebrand factor (vWF) type A domain K06238 - - 0.0003514 55.0
HKD1_k127_3732336_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 383.0
HKD1_k127_3732336_6 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 381.0
HKD1_k127_3732336_7 Cytochrome P450 K15981 - 1.14.13.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 341.0
HKD1_k127_3732336_8 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 324.0
HKD1_k127_3732336_9 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 317.0
HKD1_k127_3757435_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 5.141e-211 665.0
HKD1_k127_3757435_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 599.0
HKD1_k127_3757435_10 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
HKD1_k127_3757435_11 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 389.0
HKD1_k127_3757435_12 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 387.0
HKD1_k127_3757435_13 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 375.0
HKD1_k127_3757435_14 Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate K09018 GO:0003674,GO:0003824,GO:0004497,GO:0006139,GO:0006206,GO:0006208,GO:0006210,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0017144,GO:0019740,GO:0019859,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0052614,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.99.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 375.0
HKD1_k127_3757435_15 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 368.0
HKD1_k127_3757435_16 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 350.0
HKD1_k127_3757435_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 356.0
HKD1_k127_3757435_18 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 361.0
HKD1_k127_3757435_19 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 349.0
HKD1_k127_3757435_2 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 575.0
HKD1_k127_3757435_20 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 325.0
HKD1_k127_3757435_21 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 306.0
HKD1_k127_3757435_22 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 293.0
HKD1_k127_3757435_23 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 287.0
HKD1_k127_3757435_24 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003062 272.0
HKD1_k127_3757435_25 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000004804 267.0
HKD1_k127_3757435_26 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
HKD1_k127_3757435_27 PFAM MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007374 259.0
HKD1_k127_3757435_28 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000008295 254.0
HKD1_k127_3757435_29 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000002371 234.0
HKD1_k127_3757435_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 530.0
HKD1_k127_3757435_30 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000003169 250.0
HKD1_k127_3757435_31 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000001605 220.0
HKD1_k127_3757435_32 - - - - 0.000000000000000000000000000000000000000000000000000000000003401 223.0
HKD1_k127_3757435_33 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000000000000000000000000000000009265 216.0
HKD1_k127_3757435_34 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000001332 218.0
HKD1_k127_3757435_35 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000001903 206.0
HKD1_k127_3757435_36 FMN reductase (NADPH) activity - - - 0.00000000000000000000000000000000000000000000000001169 187.0
HKD1_k127_3757435_37 Glutathione S-transferase, C-terminal domain K03599 - - 0.00000000000000000000000000000000000000000000000008755 203.0
HKD1_k127_3757435_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001066 190.0
HKD1_k127_3757435_39 COG1994 Zn-dependent proteases - - - 0.00000000000000000000000000000000000000000003969 185.0
HKD1_k127_3757435_4 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 549.0
HKD1_k127_3757435_40 - - - - 0.0000000000000000000000000000000000000000003373 164.0
HKD1_k127_3757435_41 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000001354 177.0
HKD1_k127_3757435_42 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000001919 170.0
HKD1_k127_3757435_43 CHRD domain - - - 0.000000000000000000000000000000000000000002055 163.0
HKD1_k127_3757435_44 - - - - 0.000000000000000000000000000000000000001837 151.0
HKD1_k127_3757435_45 transcriptional regulator - - - 0.0000000000000000000000002835 115.0
HKD1_k127_3757435_46 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000006139 114.0
HKD1_k127_3757435_47 YCII-related domain - - - 0.0000000000000000004407 97.0
HKD1_k127_3757435_48 YCII-related domain - - - 0.0000000000000003374 89.0
HKD1_k127_3757435_49 Acetyltransferase (GNAT) family - - - 0.00000000003097 72.0
HKD1_k127_3757435_5 dioxygenase K11159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 495.0
HKD1_k127_3757435_50 Forkhead associated domain K03466 - - 0.00000003919 66.0
HKD1_k127_3757435_52 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000001437 61.0
HKD1_k127_3757435_53 Enoyl-(Acyl carrier protein) reductase - - - 0.000008012 50.0
HKD1_k127_3757435_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 462.0
HKD1_k127_3757435_7 NADH flavin oxidoreductase NADH oxidase K22347 - 1.8.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 463.0
HKD1_k127_3757435_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 441.0
HKD1_k127_3757435_9 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
HKD1_k127_3869150_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.996e-198 634.0
HKD1_k127_3869150_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 415.0
HKD1_k127_3869150_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 298.0
HKD1_k127_3869150_3 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001486 260.0
HKD1_k127_3869150_4 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000004729 201.0
HKD1_k127_3869150_5 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000002579 181.0
HKD1_k127_3869150_6 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000008042 135.0
HKD1_k127_3869150_7 - - - - 0.000000000000000000001303 108.0
HKD1_k127_3869150_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000002305 63.0
HKD1_k127_3869150_9 alginic acid biosynthetic process K07004,K15125,K20276 - - 0.00003089 57.0
HKD1_k127_395156_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 2.944e-252 799.0
HKD1_k127_395156_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 4.164e-212 671.0
HKD1_k127_395156_10 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 431.0
HKD1_k127_395156_11 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 420.0
HKD1_k127_395156_12 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 422.0
HKD1_k127_395156_13 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 440.0
HKD1_k127_395156_14 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 411.0
HKD1_k127_395156_15 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 379.0
HKD1_k127_395156_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 333.0
HKD1_k127_395156_17 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 310.0
HKD1_k127_395156_18 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 314.0
HKD1_k127_395156_19 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 320.0
HKD1_k127_395156_2 heat shock protein 70 K04043 - - 5.955e-203 644.0
HKD1_k127_395156_20 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 306.0
HKD1_k127_395156_21 protein localization to T-tubule K10380,K15502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 314.0
HKD1_k127_395156_22 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 296.0
HKD1_k127_395156_23 unsaturated fatty acid biosynthetic process K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004168 295.0
HKD1_k127_395156_24 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 266.0
HKD1_k127_395156_25 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 263.0
HKD1_k127_395156_26 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004226 279.0
HKD1_k127_395156_27 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005502 256.0
HKD1_k127_395156_28 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004925 250.0
HKD1_k127_395156_29 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000004974 242.0
HKD1_k127_395156_3 GAD domain K01876 - 6.1.1.12 2.082e-197 631.0
HKD1_k127_395156_30 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002538 233.0
HKD1_k127_395156_31 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000003264 216.0
HKD1_k127_395156_32 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000008832 201.0
HKD1_k127_395156_33 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000006343 191.0
HKD1_k127_395156_34 protein heterodimerization activity - - - 0.000000000000000000000000000000000000000000000101 176.0
HKD1_k127_395156_35 Alpha beta - - - 0.000000000000000000000000000000000000000000002053 181.0
HKD1_k127_395156_36 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000001445 184.0
HKD1_k127_395156_37 serine threonine protein kinase - - - 0.000000000000000000000000000000000000006302 168.0
HKD1_k127_395156_38 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000009309 127.0
HKD1_k127_395156_39 Methyltransferase domain - - - 0.0000000000000000000000001359 114.0
HKD1_k127_395156_4 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 601.0
HKD1_k127_395156_40 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000002553 121.0
HKD1_k127_395156_41 Domain of unknown function (DUF4114) - - - 0.00000000000000000000003829 111.0
HKD1_k127_395156_42 DnaJ molecular chaperone homology domain - - - 0.000000000000000000001928 106.0
HKD1_k127_395156_43 Helix-turn-helix domain - - - 0.000000000000000000003932 102.0
HKD1_k127_395156_44 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000005392 102.0
HKD1_k127_395156_45 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000007672 87.0
HKD1_k127_395156_46 ATP-dependent DNA helicase RecQ K03169 - 5.99.1.2 0.0000000000001373 74.0
HKD1_k127_395156_47 DnaJ molecular chaperone homology domain - - - 0.000000000001084 72.0
HKD1_k127_395156_48 - - - - 0.0000000001139 77.0
HKD1_k127_395156_49 - - - - 0.0000001653 61.0
HKD1_k127_395156_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 572.0
HKD1_k127_395156_50 Protein tyrosine serine phosphatase - - - 0.0000004733 63.0
HKD1_k127_395156_51 - - - - 0.000002943 62.0
HKD1_k127_395156_52 methyltransferase - - - 0.000003673 60.0
HKD1_k127_395156_53 Photosynthesis system II assembly factor YCF48 - - - 0.00001638 57.0
HKD1_k127_395156_6 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 555.0
HKD1_k127_395156_7 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 522.0
HKD1_k127_395156_8 dioxygenase K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 482.0
HKD1_k127_395156_9 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 454.0
HKD1_k127_401826_0 Transglycosylase - - - 9.175e-309 979.0
HKD1_k127_401826_1 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 4.133e-240 768.0
HKD1_k127_401826_10 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 337.0
HKD1_k127_401826_11 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 341.0
HKD1_k127_401826_12 Belongs to the methyltransferase superfamily K06969,K12297 - 2.1.1.173,2.1.1.191,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 335.0
HKD1_k127_401826_13 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 302.0
HKD1_k127_401826_14 PFAM CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 296.0
HKD1_k127_401826_15 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 293.0
HKD1_k127_401826_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007011 280.0
HKD1_k127_401826_17 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001368 271.0
HKD1_k127_401826_18 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000001347 249.0
HKD1_k127_401826_19 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000004844 247.0
HKD1_k127_401826_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 608.0
HKD1_k127_401826_20 - - - - 0.00000000000000000000000000000000000000008716 172.0
HKD1_k127_401826_21 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000003314 167.0
HKD1_k127_401826_22 N-acetyltransferase K00675 - 2.3.1.118 0.00000000000000000000000000000000001699 152.0
HKD1_k127_401826_23 Histidine kinase - - - 0.00000000000000000000000000000001149 148.0
HKD1_k127_401826_24 Phage shock protein A, PspA K03969 - - 0.0000000000000000000000000000001084 134.0
HKD1_k127_401826_25 SnoaL-like domain - - - 0.000000000000000000000000000004977 126.0
HKD1_k127_401826_26 Homologues of snake disintegrins - - - 0.000000000000000000000001512 121.0
HKD1_k127_401826_27 - - - - 0.00000000000000000004927 107.0
HKD1_k127_401826_28 lactoylglutathione lyase activity - - - 0.00000000000002886 77.0
HKD1_k127_401826_29 cellulose binding K12132 - 2.7.11.1 0.0000000009965 72.0
HKD1_k127_401826_3 peptidase S15 K06978 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 548.0
HKD1_k127_401826_4 With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 479.0
HKD1_k127_401826_5 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 448.0
HKD1_k127_401826_6 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 474.0
HKD1_k127_401826_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 422.0
HKD1_k127_401826_8 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 431.0
HKD1_k127_401826_9 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 402.0
HKD1_k127_4044798_0 Insulinase (Peptidase family M16) K07263 - - 1.281e-194 640.0
HKD1_k127_4044798_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 405.0
HKD1_k127_4044798_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001768 260.0
HKD1_k127_4044798_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000001638 192.0
HKD1_k127_4044798_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000423 176.0
HKD1_k127_4044798_5 - - - - 0.0000000000000000009435 88.0
HKD1_k127_4044798_6 - - - - 0.000000003205 60.0
HKD1_k127_4056717_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 520.0
HKD1_k127_4056717_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 351.0
HKD1_k127_4056717_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000002093 206.0
HKD1_k127_4056717_3 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000005722 183.0
HKD1_k127_4056717_4 AAA ATPase domain - - - 0.000000000000000000000000000000000003978 160.0
HKD1_k127_4056717_5 Rieske 2Fe-2S - - - 0.00000000000000000000000000001312 120.0
HKD1_k127_4056717_6 Alpha beta hydrolase - - - 0.00000000000000000000002762 117.0
HKD1_k127_4056717_7 Glycine-zipper domain - - - 0.0000000000000000000004519 111.0
HKD1_k127_4056717_9 Evidence 4 Homologs of previously reported genes of - - - 0.00002557 46.0
HKD1_k127_4074552_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 419.0
HKD1_k127_4074552_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 373.0
HKD1_k127_4074552_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000005326 218.0
HKD1_k127_4074552_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000259 197.0
HKD1_k127_4074552_4 Lysin motif K06194 - - 0.000000000000000000000000000000000000001796 164.0
HKD1_k127_4074552_5 YhhN family - - - 0.0000000000000000000000000000005257 129.0
HKD1_k127_4074552_6 - - - - 0.000000000000000000001824 105.0
HKD1_k127_4106341_0 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 593.0
HKD1_k127_4106341_1 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 563.0
HKD1_k127_4106341_10 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000308 230.0
HKD1_k127_4106341_11 permease - - - 0.00000000000000000000000000000000000000000000000000000000172 222.0
HKD1_k127_4106341_12 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000004213 206.0
HKD1_k127_4106341_13 2-oxopent-4-enoate hydratase activity - - - 0.0000000000000000000000000000000000000000000000000000006709 201.0
HKD1_k127_4106341_14 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000002748 213.0
HKD1_k127_4106341_15 Nitroreductase - - - 0.0000000000000000000000000000000000000000000006845 190.0
HKD1_k127_4106341_16 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000003308 164.0
HKD1_k127_4106341_17 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000005639 139.0
HKD1_k127_4106341_19 PHP domain protein - - - 0.00000000008438 74.0
HKD1_k127_4106341_2 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 558.0
HKD1_k127_4106341_20 - - - - 0.00005899 51.0
HKD1_k127_4106341_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 564.0
HKD1_k127_4106341_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 507.0
HKD1_k127_4106341_5 cytochrome P-450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 528.0
HKD1_k127_4106341_6 aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 359.0
HKD1_k127_4106341_7 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 321.0
HKD1_k127_4106341_8 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 295.0
HKD1_k127_4106341_9 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000006904 252.0
HKD1_k127_4123236_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 545.0
HKD1_k127_4123236_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 482.0
HKD1_k127_4123236_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 353.0
HKD1_k127_4123236_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 364.0
HKD1_k127_4123236_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 331.0
HKD1_k127_4123236_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004338 250.0
HKD1_k127_4123236_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000003921 194.0
HKD1_k127_4124573_0 PFAM AMP-dependent synthetase and ligase K00666 - - 5.389e-303 969.0
HKD1_k127_4124573_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.509e-239 751.0
HKD1_k127_4124573_10 SnoaL-like domain - - - 0.00000000000000000002383 102.0
HKD1_k127_4124573_11 transcriptional regulator - - - 0.0000007557 60.0
HKD1_k127_4124573_2 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 442.0
HKD1_k127_4124573_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 396.0
HKD1_k127_4124573_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000001326 239.0
HKD1_k127_4124573_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000001261 236.0
HKD1_k127_4124573_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000002573 207.0
HKD1_k127_4124573_7 SnoaL-like domain - - - 0.000000000000000000000000009298 113.0
HKD1_k127_4124573_8 lactoylglutathione lyase activity - - - 0.00000000000000000000000001621 115.0
HKD1_k127_4124573_9 SnoaL-like domain - - - 0.00000000000000000000009332 102.0
HKD1_k127_4169761_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K04090 - 1.2.7.8 1.59e-246 805.0
HKD1_k127_4169761_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 398.0
HKD1_k127_4169761_10 Bacterial regulatory proteins, tetR family K22107 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000001647 116.0
HKD1_k127_4169761_11 Divergent 4Fe-4S mono-cluster K05337 - - 0.00000000000000000000783 93.0
HKD1_k127_4169761_12 - - - - 0.0000000007411 71.0
HKD1_k127_4169761_13 8-oxoguanine DNA glycosylase K01247,K13529 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.0000001898 63.0
HKD1_k127_4169761_14 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) - - - 0.00002037 54.0
HKD1_k127_4169761_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 403.0
HKD1_k127_4169761_3 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 353.0
HKD1_k127_4169761_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 302.0
HKD1_k127_4169761_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003282 293.0
HKD1_k127_4169761_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 270.0
HKD1_k127_4169761_7 Domain of unknown function (DUF4129) - - - 0.000000000000000000000000000000000000000000000000000000000000000008646 243.0
HKD1_k127_4169761_8 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000002661 197.0
HKD1_k127_4169761_9 Domain of unknown function (DUF4350) - - - 0.00000000000000000000000000000000000000001048 177.0
HKD1_k127_4175448_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.697e-211 710.0
HKD1_k127_4175448_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005698 246.0
HKD1_k127_4175448_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000003104 248.0
HKD1_k127_4175448_3 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000001101 206.0
HKD1_k127_4175448_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000752 155.0
HKD1_k127_4175448_5 Protein of unknown function (DUF1329) - - - 0.00000000000000000000004 114.0
HKD1_k127_4175448_6 transcriptional regulator - - - 0.00000000000000000001773 98.0
HKD1_k127_4247358_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 1.298e-255 819.0
HKD1_k127_4247358_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 2.609e-217 711.0
HKD1_k127_4247358_10 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 381.0
HKD1_k127_4247358_11 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 386.0
HKD1_k127_4247358_12 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 349.0
HKD1_k127_4247358_13 Pfam Transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 353.0
HKD1_k127_4247358_14 Belongs to the DegT DnrJ EryC1 family K16016 - 4.2.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 317.0
HKD1_k127_4247358_15 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 308.0
HKD1_k127_4247358_16 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 295.0
HKD1_k127_4247358_17 Major royal jelly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002502 281.0
HKD1_k127_4247358_18 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007342 280.0
HKD1_k127_4247358_19 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 268.0
HKD1_k127_4247358_2 belongs to the thiolase family K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 610.0
HKD1_k127_4247358_20 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000008887 259.0
HKD1_k127_4247358_21 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001724 250.0
HKD1_k127_4247358_22 Mate efflux family protein K03327 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000455 220.0
HKD1_k127_4247358_23 PFAM aminoglycoside phosphotransferase K04343 - 2.7.1.72 0.000000000000000000000000000000000000000000000000000000008829 217.0
HKD1_k127_4247358_24 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000001474 201.0
HKD1_k127_4247358_25 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000001049 193.0
HKD1_k127_4247358_26 response to oxidative stress - - - 0.00000000000000000000000000000000000000000000000004579 181.0
HKD1_k127_4247358_27 - - - - 0.0000000000000000000000000000000000000000000000007712 179.0
HKD1_k127_4247358_28 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000004301 175.0
HKD1_k127_4247358_29 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000004296 165.0
HKD1_k127_4247358_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 593.0
HKD1_k127_4247358_30 Transcriptional regulator - - - 0.00000000000000000000000000000000000000004424 172.0
HKD1_k127_4247358_31 FMN_bind - - - 0.000000000000000000000000000000000000005946 152.0
HKD1_k127_4247358_32 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000005539 146.0
HKD1_k127_4247358_33 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000001498 158.0
HKD1_k127_4247358_34 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000001951 149.0
HKD1_k127_4247358_35 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000357 143.0
HKD1_k127_4247358_36 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000005695 116.0
HKD1_k127_4247358_37 Protein of unknown function (DUF1232) - - - 0.000000000000000000000001077 109.0
HKD1_k127_4247358_38 PFAM alpha beta hydrolase fold - - - 0.00000000000000000001917 101.0
HKD1_k127_4247358_39 PFAM PHP domain K07053 - 3.1.3.97 0.00000000000000000004014 102.0
HKD1_k127_4247358_4 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 514.0
HKD1_k127_4247358_40 WHG domain - - - 0.000000000000001474 91.0
HKD1_k127_4247358_41 PFAM regulatory protein TetR - - - 0.000000000000004405 83.0
HKD1_k127_4247358_42 Amidohydrolase K07045 - - 0.0000000000003659 79.0
HKD1_k127_4247358_43 PFAM MaoC domain protein dehydratase - - - 0.000000000007917 76.0
HKD1_k127_4247358_44 - - - - 0.00000002573 58.0
HKD1_k127_4247358_45 Belongs to the UPF0336 family - - - 0.000008038 58.0
HKD1_k127_4247358_5 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 462.0
HKD1_k127_4247358_6 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 454.0
HKD1_k127_4247358_7 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 445.0
HKD1_k127_4247358_8 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 421.0
HKD1_k127_4247358_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 403.0
HKD1_k127_4266333_0 PFAM amino acid permease-associated region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 436.0
HKD1_k127_4266333_1 COG0183 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 353.0
HKD1_k127_4266333_2 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 279.0
HKD1_k127_4266333_3 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000001088 200.0
HKD1_k127_4266333_4 MaoC like domain - - - 0.0000000000000000000000000000000000000000006251 170.0
HKD1_k127_4266333_5 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000005817 100.0
HKD1_k127_4324820_0 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 581.0
HKD1_k127_4324820_1 synthetase K00666,K18688 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576 6.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 542.0
HKD1_k127_4324820_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 450.0
HKD1_k127_4324820_3 MMPL family K06994,K20470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 411.0
HKD1_k127_4324820_4 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 344.0
HKD1_k127_4324820_5 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 319.0
HKD1_k127_4324820_6 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 302.0
HKD1_k127_4324820_7 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007022 275.0
HKD1_k127_4324820_8 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000001953 154.0
HKD1_k127_4324820_9 FR47-like protein - - - 0.0000000000000000444 88.0
HKD1_k127_4326256_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 4.359e-271 847.0
HKD1_k127_4326256_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 551.0
HKD1_k127_4326256_10 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000001179 127.0
HKD1_k127_4326256_11 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000004984 74.0
HKD1_k127_4326256_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 452.0
HKD1_k127_4326256_3 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 432.0
HKD1_k127_4326256_4 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 389.0
HKD1_k127_4326256_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 332.0
HKD1_k127_4326256_6 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002428 307.0
HKD1_k127_4326256_7 ATP cone domain K05715 - - 0.000000000000000000000000000000000000000000000000000000000000002934 231.0
HKD1_k127_4326256_8 PFAM metallophosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000001934 169.0
HKD1_k127_4326256_9 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000182 166.0
HKD1_k127_4329677_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 2.481e-255 833.0
HKD1_k127_4329677_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 8.742e-234 729.0
HKD1_k127_4329677_10 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000007175 173.0
HKD1_k127_4329677_11 - - - - 0.00000000000000000000000000000000000000000003436 164.0
HKD1_k127_4329677_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000005857 134.0
HKD1_k127_4329677_13 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000004776 106.0
HKD1_k127_4329677_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 522.0
HKD1_k127_4329677_3 chromate transport K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 423.0
HKD1_k127_4329677_4 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 396.0
HKD1_k127_4329677_5 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 351.0
HKD1_k127_4329677_6 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 350.0
HKD1_k127_4329677_7 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 318.0
HKD1_k127_4329677_8 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 327.0
HKD1_k127_4329677_9 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000003769 219.0
HKD1_k127_4337253_0 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 582.0
HKD1_k127_4337253_1 Belongs to the alpha-IPM synthase homocitrate synthase family K09011 - 2.3.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 532.0
HKD1_k127_4337253_10 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000004039 224.0
HKD1_k127_4337253_11 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000006567 194.0
HKD1_k127_4337253_12 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000005308 191.0
HKD1_k127_4337253_13 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000001492 154.0
HKD1_k127_4337253_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000001605 114.0
HKD1_k127_4337253_15 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000001073 114.0
HKD1_k127_4337253_16 Protein of unknown function (DUF3106) - - - 0.00000000000000008496 88.0
HKD1_k127_4337253_17 metal-dependent phosphoesterases (PHP family) - - - 0.00000000001123 77.0
HKD1_k127_4337253_18 Hypothetical methyltransferase - - - 0.00000000005251 74.0
HKD1_k127_4337253_19 Acetyltransferase (GNAT) domain - - - 0.0000000005524 70.0
HKD1_k127_4337253_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 426.0
HKD1_k127_4337253_20 Tetratricopeptide repeat - - - 0.0000007004 55.0
HKD1_k127_4337253_21 HEAT repeats - - - 0.00001856 56.0
HKD1_k127_4337253_22 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00004161 57.0
HKD1_k127_4337253_23 TPR repeat - - - 0.0002113 54.0
HKD1_k127_4337253_3 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 418.0
HKD1_k127_4337253_4 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 369.0
HKD1_k127_4337253_5 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 345.0
HKD1_k127_4337253_6 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 313.0
HKD1_k127_4337253_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000129 296.0
HKD1_k127_4337253_8 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005352 262.0
HKD1_k127_4337253_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000001438 243.0
HKD1_k127_438565_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1974.0
HKD1_k127_438565_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1545.0
HKD1_k127_438565_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000008185 71.0
HKD1_k127_438565_11 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000005909 54.0
HKD1_k127_438565_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.95e-277 871.0
HKD1_k127_438565_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 309.0
HKD1_k127_438565_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000003956 219.0
HKD1_k127_438565_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000001231 203.0
HKD1_k127_438565_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000009819 195.0
HKD1_k127_438565_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000166 201.0
HKD1_k127_438565_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000009638 154.0
HKD1_k127_438565_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000005237 126.0
HKD1_k127_4403377_0 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 523.0
HKD1_k127_4403377_1 Rod shape-determining protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 481.0
HKD1_k127_4403377_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001157 268.0
HKD1_k127_4403377_3 Proteasome subunit K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000009745 246.0
HKD1_k127_4403377_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000001393 128.0
HKD1_k127_4403377_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000002862 117.0
HKD1_k127_4403377_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000004006 66.0
HKD1_k127_4403377_7 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000007721 63.0
HKD1_k127_4403377_8 Alkyl sulfatase C-terminal - - - 0.00005146 53.0
HKD1_k127_4435979_0 synthetase K00666 - - 8.486e-216 682.0
HKD1_k127_4435979_1 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 444.0
HKD1_k127_4435979_10 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000002724 246.0
HKD1_k127_4435979_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000001399 176.0
HKD1_k127_4435979_12 Suppressor of fused protein (SUFU) - - - 0.000000000000000000001257 111.0
HKD1_k127_4435979_13 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000141 102.0
HKD1_k127_4435979_14 - - - - 0.000000007829 64.0
HKD1_k127_4435979_15 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000008541 66.0
HKD1_k127_4435979_17 recA bacterial DNA recombination protein - - - 0.00000002623 64.0
HKD1_k127_4435979_18 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000007905 63.0
HKD1_k127_4435979_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 408.0
HKD1_k127_4435979_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K17736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 348.0
HKD1_k127_4435979_4 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001755 278.0
HKD1_k127_4435979_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002311 264.0
HKD1_k127_4435979_6 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007189 256.0
HKD1_k127_4435979_7 Aldo Keto reductase K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 248.0
HKD1_k127_4435979_8 amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000004751 254.0
HKD1_k127_4435979_9 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000002246 226.0
HKD1_k127_4501151_0 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 586.0
HKD1_k127_4501151_1 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 379.0
HKD1_k127_4501151_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000001221 209.0
HKD1_k127_4501151_3 Tetratricopeptide repeat - - - 0.0005593 49.0
HKD1_k127_4526155_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 612.0
HKD1_k127_4526155_1 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 491.0
HKD1_k127_4526155_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000004257 167.0
HKD1_k127_4526155_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000006426 165.0
HKD1_k127_4526155_12 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000002153 153.0
HKD1_k127_4526155_13 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000009247 96.0
HKD1_k127_4526155_14 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000002691 80.0
HKD1_k127_4526155_15 peptidyl-tyrosine sulfation - - - 0.000000000005078 74.0
HKD1_k127_4526155_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 426.0
HKD1_k127_4526155_3 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 425.0
HKD1_k127_4526155_4 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 413.0
HKD1_k127_4526155_5 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K00830,K03430 - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 379.0
HKD1_k127_4526155_6 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 370.0
HKD1_k127_4526155_7 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 350.0
HKD1_k127_4526155_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 316.0
HKD1_k127_4526155_9 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000002782 196.0
HKD1_k127_457259_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 424.0
HKD1_k127_457259_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 393.0
HKD1_k127_457259_2 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 355.0
HKD1_k127_457259_3 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 310.0
HKD1_k127_457259_4 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000005709 170.0
HKD1_k127_457259_5 AAA ATPase domain - - - 0.0000000000000000000000000000000415 138.0
HKD1_k127_457259_6 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000005115 123.0
HKD1_k127_457259_7 Adenylate cyclase - - - 0.00000000000000002097 93.0
HKD1_k127_457259_8 cellular response to DNA damage stimulus K07340 - - 0.0000000000001438 76.0
HKD1_k127_457259_9 Protein of unknown function (DUF1329) - - - 0.0000007032 62.0
HKD1_k127_4594248_0 Sulfatase K01130 - 3.1.6.1 5.021e-274 886.0
HKD1_k127_4594248_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 514.0
HKD1_k127_4594248_10 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002033 280.0
HKD1_k127_4594248_11 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004937 260.0
HKD1_k127_4594248_12 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006991 239.0
HKD1_k127_4594248_13 Ndr family - - - 0.000000000000000000000000000000000000000000000000000000000000000001281 239.0
HKD1_k127_4594248_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000006225 213.0
HKD1_k127_4594248_15 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000003054 186.0
HKD1_k127_4594248_16 acetyltransferase - - - 0.000000000000000000000000000000000004598 151.0
HKD1_k127_4594248_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000005772 109.0
HKD1_k127_4594248_18 helix_turn_helix, mercury resistance - - - 0.00000000000000000005873 95.0
HKD1_k127_4594248_19 SnoaL-like domain K06893 - - 0.000000000000001225 89.0
HKD1_k127_4594248_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 452.0
HKD1_k127_4594248_20 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000002034 85.0
HKD1_k127_4594248_21 F420-dependent oxidoreductase - - - 0.0000000000002427 71.0
HKD1_k127_4594248_22 palmitoyl-(protein) hydrolase activity - - - 0.000000000002659 81.0
HKD1_k127_4594248_23 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000293 53.0
HKD1_k127_4594248_24 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000005767 58.0
HKD1_k127_4594248_3 PFAM AMP-dependent synthetase and ligase K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 405.0
HKD1_k127_4594248_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 367.0
HKD1_k127_4594248_5 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 349.0
HKD1_k127_4594248_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 319.0
HKD1_k127_4594248_7 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 325.0
HKD1_k127_4594248_8 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 326.0
HKD1_k127_4594248_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001298 297.0
HKD1_k127_460165_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.035e-317 1006.0
HKD1_k127_460165_1 Aminotransferase class-III - - - 2.724e-220 702.0
HKD1_k127_460165_10 Transcriptional regulator K05799 - - 0.00000000000000000002124 102.0
HKD1_k127_460165_11 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000007102 101.0
HKD1_k127_460165_13 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000005403 75.0
HKD1_k127_460165_14 EamA-like transporter family - - - 0.000000000002688 79.0
HKD1_k127_460165_15 Phosphopantetheine attachment site K02078 - - 0.00000000008027 65.0
HKD1_k127_460165_16 Peptidase family M28 - - - 0.000000001705 68.0
HKD1_k127_460165_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 411.0
HKD1_k127_460165_4 Insecticide toxin TcdB middle/N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 405.0
HKD1_k127_460165_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 341.0
HKD1_k127_460165_6 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 331.0
HKD1_k127_460165_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005904 269.0
HKD1_k127_460165_8 Putative Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000007721 231.0
HKD1_k127_460165_9 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000000000000000000000000000000000006228 207.0
HKD1_k127_4634559_0 cobalamin binding K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1321.0
HKD1_k127_4634559_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.0 1067.0
HKD1_k127_4634559_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000003611 172.0
HKD1_k127_4634559_11 Permease of the major facilitator superfamily K08369 - - 0.000000000000000000000000000000000000006324 164.0
HKD1_k127_4634559_12 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000005083 132.0
HKD1_k127_4634559_13 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000000004597 128.0
HKD1_k127_4634559_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000008649 125.0
HKD1_k127_4634559_15 Cupin - - - 0.00000000348 70.0
HKD1_k127_4634559_16 COG1555 DNA uptake protein and related DNA-binding K02237 - - 0.00006105 54.0
HKD1_k127_4634559_2 Carboxyl transferase domain - - - 9.632e-224 703.0
HKD1_k127_4634559_3 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 507.0
HKD1_k127_4634559_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 459.0
HKD1_k127_4634559_5 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 357.0
HKD1_k127_4634559_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 326.0
HKD1_k127_4634559_7 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 305.0
HKD1_k127_4634559_8 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004973 283.0
HKD1_k127_4634559_9 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000002551 225.0
HKD1_k127_4652905_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1132.0
HKD1_k127_4652905_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 567.0
HKD1_k127_4652905_10 Belongs to the BolA IbaG family K05527 - - 0.000000000000000005431 98.0
HKD1_k127_4652905_11 acid phosphatase activity K07004 - - 0.0000000000000001973 94.0
HKD1_k127_4652905_13 Chemotaxis phosphatase CheX K03409 - - 0.000000000002831 79.0
HKD1_k127_4652905_14 subunit of a heme lyase K02200 - - 0.0000005627 64.0
HKD1_k127_4652905_2 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 427.0
HKD1_k127_4652905_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 299.0
HKD1_k127_4652905_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000001271 244.0
HKD1_k127_4652905_5 acetylesterase activity K01066 - - 0.000000000000000000000000000000000000000000000000000000000002342 220.0
HKD1_k127_4652905_6 Evidence 2b Function of strongly homologous gene K03406 - - 0.000000000000000000000000000000000000000000002257 181.0
HKD1_k127_4652905_7 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000003085 129.0
HKD1_k127_4652905_8 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000038 129.0
HKD1_k127_4652905_9 Two component signalling adaptor domain K03408 - - 0.00000000000000000043 104.0
HKD1_k127_475206_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.388e-221 697.0
HKD1_k127_475206_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 582.0
HKD1_k127_475206_10 - - - - 0.00000000000000000000000000000000000000000449 168.0
HKD1_k127_475206_11 Nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000008492 157.0
HKD1_k127_475206_12 transcriptional regulator K22107 - - 0.00000000000000000000000000008147 124.0
HKD1_k127_475206_13 SnoaL-like domain - - - 0.000000000000000000008455 100.0
HKD1_k127_475206_14 phosphinothricin N-acetyltransferase activity - - - 0.0000000001336 75.0
HKD1_k127_475206_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 475.0
HKD1_k127_475206_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 457.0
HKD1_k127_475206_4 lipid-transfer protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 439.0
HKD1_k127_475206_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 347.0
HKD1_k127_475206_6 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 336.0
HKD1_k127_475206_7 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 316.0
HKD1_k127_475206_8 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 330.0
HKD1_k127_475206_9 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000000000051 198.0
HKD1_k127_4754997_0 Sulfatase - - - 0.0 1016.0
HKD1_k127_4754997_1 PFAM transcriptional regulator domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 529.0
HKD1_k127_4754997_10 Preprotein translocase subunit SecA (ATPase, RNA helicase) - - - 0.000000003803 64.0
HKD1_k127_4754997_2 Major facilitator superfamily - GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 404.0
HKD1_k127_4754997_3 FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 362.0
HKD1_k127_4754997_4 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
HKD1_k127_4754997_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000118 211.0
HKD1_k127_4754997_6 Permease of the major facilitator superfamily K08369 - - 0.000000000000000000000000000000000000000341 166.0
HKD1_k127_4754997_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000005846 140.0
HKD1_k127_4754997_9 EamA-like transporter family - - - 0.00000000001503 78.0
HKD1_k127_4851314_0 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1445.0
HKD1_k127_4851314_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1285.0
HKD1_k127_4851314_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 519.0
HKD1_k127_4851314_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 506.0
HKD1_k127_4851314_12 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 457.0
HKD1_k127_4851314_13 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 458.0
HKD1_k127_4851314_14 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 444.0
HKD1_k127_4851314_15 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 434.0
HKD1_k127_4851314_16 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 437.0
HKD1_k127_4851314_17 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 432.0
HKD1_k127_4851314_18 PFAM aldo keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 396.0
HKD1_k127_4851314_19 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 394.0
HKD1_k127_4851314_2 ABC-type multidrug transport system, ATPase component K13926 - - 0.0 1148.0
HKD1_k127_4851314_20 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 351.0
HKD1_k127_4851314_21 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 361.0
HKD1_k127_4851314_22 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 310.0
HKD1_k127_4851314_23 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 270.0
HKD1_k127_4851314_24 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002489 257.0
HKD1_k127_4851314_25 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000003218 242.0
HKD1_k127_4851314_26 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000001861 220.0
HKD1_k127_4851314_27 Protein of unknown function (DUF4056) - - - 0.0000000000000000000000000000000000000000000000000000000002863 218.0
HKD1_k127_4851314_28 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000002265 186.0
HKD1_k127_4851314_29 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000001833 173.0
HKD1_k127_4851314_3 Succinyl-CoA ligase like flavodoxin domain K09181 - - 1.853e-306 964.0
HKD1_k127_4851314_30 - - - - 0.0000000000000000000000000000000000000000000003279 171.0
HKD1_k127_4851314_31 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000000000521 164.0
HKD1_k127_4851314_32 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000002456 148.0
HKD1_k127_4851314_33 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000003511 122.0
HKD1_k127_4851314_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000002857 116.0
HKD1_k127_4851314_35 Zn peptidase - - - 0.00000000000000000005052 104.0
HKD1_k127_4851314_37 - - - - 0.00000001514 63.0
HKD1_k127_4851314_38 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000006982 56.0
HKD1_k127_4851314_4 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.099e-297 930.0
HKD1_k127_4851314_5 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 6.086e-292 919.0
HKD1_k127_4851314_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 4.22e-259 821.0
HKD1_k127_4851314_7 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 555.0
HKD1_k127_4851314_8 Alcohol dehydrogenase GroES-like domain K18369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 552.0
HKD1_k127_4851314_9 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 524.0
HKD1_k127_4855560_0 Flavoprotein involved in K transport K03379 - 1.14.13.22 2.906e-275 858.0
HKD1_k127_4855560_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000002838 181.0
HKD1_k127_4855560_2 tRNA modification K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000007854 175.0
HKD1_k127_4855560_3 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000003137 126.0
HKD1_k127_4855560_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000003445 96.0
HKD1_k127_4855560_5 transcriptional regulator - - - 0.0000000000000000001917 104.0
HKD1_k127_4855560_6 lipid-transfer protein - - - 0.000000000000001984 76.0
HKD1_k127_4855560_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000738 50.0
HKD1_k127_4881992_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.146e-225 721.0
HKD1_k127_4881992_1 Belongs to the RtcB family K14415 - 6.5.1.3 2.845e-199 632.0
HKD1_k127_4881992_10 TIGRFAM Diguanylate cyclase K21022 - 2.7.7.65 0.0000000000000000000000000000000000002909 145.0
HKD1_k127_4881992_11 - - - - 0.0000000000000000000000000000000008364 143.0
HKD1_k127_4881992_12 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000008893 104.0
HKD1_k127_4881992_13 Phosphopantetheine attachment site - - - 0.000000000000000002583 98.0
HKD1_k127_4881992_14 BON domain - - - 0.0000000000000001068 90.0
HKD1_k127_4881992_15 'Cold-shock' DNA-binding domain - - - 0.000000000006191 76.0
HKD1_k127_4881992_2 Transketolase, C-terminal domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 509.0
HKD1_k127_4881992_3 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 501.0
HKD1_k127_4881992_4 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 454.0
HKD1_k127_4881992_5 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 351.0
HKD1_k127_4881992_6 Domain of unknown function(DUF2779) - - - 0.00000000000000000000000000000000000000000000000000000000000002905 243.0
HKD1_k127_4881992_7 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000001026 206.0
HKD1_k127_4881992_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000001516 192.0
HKD1_k127_4881992_9 alpha-ribazole phosphatase activity K00768,K15634 - 2.4.2.21,5.4.2.12 0.000000000000000000000000000000000000000000000904 175.0
HKD1_k127_4912999_0 Acetyl-CoA carboxylase, central region - - - 0.0 1184.0
HKD1_k127_4912999_1 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 311.0
HKD1_k127_4912999_2 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000003418 202.0
HKD1_k127_4912999_3 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000003782 177.0
HKD1_k127_4912999_4 phosphoribosyl-AMP cyclohydrolase activity K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000002613 172.0
HKD1_k127_4942615_0 FAD linked K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 527.0
HKD1_k127_4942615_1 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 464.0
HKD1_k127_4942615_10 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000005345 265.0
HKD1_k127_4942615_11 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003416 246.0
HKD1_k127_4942615_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
HKD1_k127_4942615_13 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000001286 241.0
HKD1_k127_4942615_14 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000468 236.0
HKD1_k127_4942615_15 - - - - 0.00000000000000000000000000000000000000000000000000004594 214.0
HKD1_k127_4942615_16 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000004859 186.0
HKD1_k127_4942615_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000003118 158.0
HKD1_k127_4942615_18 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.000000000000000000000001304 121.0
HKD1_k127_4942615_19 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000005727 116.0
HKD1_k127_4942615_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 463.0
HKD1_k127_4942615_20 Belongs to the UPF0102 family K07460 - - 0.000000000000000005463 98.0
HKD1_k127_4942615_21 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000001536 87.0
HKD1_k127_4942615_22 Bacterial regulatory proteins, tetR family - - - 0.00000000000005258 80.0
HKD1_k127_4942615_23 mitochondrial translation K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001232 74.0
HKD1_k127_4942615_24 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000002219 72.0
HKD1_k127_4942615_25 Belongs to the UPF0109 family K06960 - - 0.00000000000034 73.0
HKD1_k127_4942615_26 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000009653 72.0
HKD1_k127_4942615_27 Protein of unknown function (DUF721) - - - 0.000000000005413 72.0
HKD1_k127_4942615_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 415.0
HKD1_k127_4942615_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 407.0
HKD1_k127_4942615_5 Trypsin K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 382.0
HKD1_k127_4942615_6 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 376.0
HKD1_k127_4942615_7 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 322.0
HKD1_k127_4942615_8 cytochrome p450 K21033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 313.0
HKD1_k127_4942615_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 311.0
HKD1_k127_4972946_0 CoA-transferase family III K07749,K08298 - 2.8.3.16,2.8.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 451.0
HKD1_k127_4972946_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 325.0
HKD1_k127_4972946_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000008345 271.0
HKD1_k127_4972946_3 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000003173 177.0
HKD1_k127_4972946_4 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000001214 153.0
HKD1_k127_4972946_5 - - - - 0.000000000000000000000000000000006479 141.0
HKD1_k127_4972946_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000005491 63.0
HKD1_k127_4972946_7 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.0007819 53.0
HKD1_k127_5025125_0 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 504.0
HKD1_k127_5025125_1 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 473.0
HKD1_k127_5025125_10 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000001421 158.0
HKD1_k127_5025125_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000344 143.0
HKD1_k127_5025125_12 ThiS family K03636 - - 0.00000000000000001252 98.0
HKD1_k127_5025125_13 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000003285 94.0
HKD1_k127_5025125_14 Lysyl oxidase K00277 GO:0001568,GO:0001944,GO:0003674,GO:0003824,GO:0004720,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005581,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006807,GO:0006950,GO:0007275,GO:0007507,GO:0008150,GO:0008152,GO:0009611,GO:0009653,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0019538,GO:0022607,GO:0030198,GO:0030199,GO:0030323,GO:0030324,GO:0031012,GO:0032501,GO:0032502,GO:0032991,GO:0033993,GO:0035239,GO:0035295,GO:0035904,GO:0036211,GO:0042060,GO:0042221,GO:0042493,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0048251,GO:0048513,GO:0048514,GO:0048545,GO:0048731,GO:0048856,GO:0050896,GO:0055114,GO:0060541,GO:0060840,GO:0071704,GO:0071840,GO:0072358,GO:0072359,GO:0085029,GO:0097435,GO:0140096,GO:1901564 1.4.3.13 0.0000000000001414 84.0
HKD1_k127_5025125_16 Protein of unknown function (DUF952) - - - 0.00002922 56.0
HKD1_k127_5025125_2 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 415.0
HKD1_k127_5025125_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 372.0
HKD1_k127_5025125_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005452 283.0
HKD1_k127_5025125_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008197 279.0
HKD1_k127_5025125_6 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003042 292.0
HKD1_k127_5025125_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000001173 188.0
HKD1_k127_5025125_8 Dna alkylation repair - - - 0.0000000000000000000000000000000000000000000000002106 193.0
HKD1_k127_5025125_9 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000005638 172.0
HKD1_k127_5088911_0 amine dehydrogenase activity - - - 4.571e-277 885.0
HKD1_k127_5088911_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 6.939e-276 872.0
HKD1_k127_5088911_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 372.0
HKD1_k127_5088911_11 Cysteine-rich domain K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 333.0
HKD1_k127_5088911_12 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002506 290.0
HKD1_k127_5088911_13 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002996 270.0
HKD1_k127_5088911_14 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006824 259.0
HKD1_k127_5088911_15 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
HKD1_k127_5088911_16 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000005148 212.0
HKD1_k127_5088911_17 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000002904 221.0
HKD1_k127_5088911_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000002249 197.0
HKD1_k127_5088911_19 - - - - 0.00000000000000000000000000000000000000000000000006245 184.0
HKD1_k127_5088911_2 amine dehydrogenase activity - - - 1.564e-265 850.0
HKD1_k127_5088911_20 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000002821 168.0
HKD1_k127_5088911_21 Transcriptional - - - 0.000000000000000000000000000000000003058 142.0
HKD1_k127_5088911_22 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000001977 148.0
HKD1_k127_5088911_23 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.000000000000000000000000000000001612 139.0
HKD1_k127_5088911_24 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000004406 132.0
HKD1_k127_5088911_25 Rdx family K07401 - - 0.000000000000000000000000000000006253 129.0
HKD1_k127_5088911_26 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000277 143.0
HKD1_k127_5088911_27 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000002923 135.0
HKD1_k127_5088911_28 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.0000000000000000000000000002295 128.0
HKD1_k127_5088911_29 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000001787 115.0
HKD1_k127_5088911_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 616.0
HKD1_k127_5088911_30 Belongs to the Fur family K09825 - - 0.000000000000000000000002521 117.0
HKD1_k127_5088911_31 Calcineurin-like phosphoesterase - - - 0.00000002156 67.0
HKD1_k127_5088911_4 sulfuric ester hydrolase activity K07014 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 563.0
HKD1_k127_5088911_5 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 508.0
HKD1_k127_5088911_6 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 512.0
HKD1_k127_5088911_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 468.0
HKD1_k127_5088911_8 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 434.0
HKD1_k127_5088911_9 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 413.0
HKD1_k127_5101382_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 618.0
HKD1_k127_5101382_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 533.0
HKD1_k127_5101382_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001333 254.0
HKD1_k127_5101382_11 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000002811 250.0
HKD1_k127_5101382_12 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000001092 220.0
HKD1_k127_5101382_13 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000000000000000000000005898 220.0
HKD1_k127_5101382_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000005788 181.0
HKD1_k127_5101382_15 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000005257 174.0
HKD1_k127_5101382_16 stress protein (general stress protein 26) - - - 0.000000000000000000000000000000000000000006685 169.0
HKD1_k127_5101382_17 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000002325 161.0
HKD1_k127_5101382_18 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000002524 150.0
HKD1_k127_5101382_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 415.0
HKD1_k127_5101382_20 FAD binding domain - - - 0.00000000000000000000000000009531 130.0
HKD1_k127_5101382_21 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000001909 118.0
HKD1_k127_5101382_22 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000003826 116.0
HKD1_k127_5101382_23 Alpha beta hydrolase K00627 - 2.3.1.12 0.00000000000000000000001331 116.0
HKD1_k127_5101382_24 PilZ domain K02676 - - 0.00000000000000001039 87.0
HKD1_k127_5101382_25 lactoylglutathione lyase activity K08234 - - 0.000000000000002603 78.0
HKD1_k127_5101382_26 - - - - 0.0000000004021 71.0
HKD1_k127_5101382_27 Transglycosylase SLT domain - - - 0.000000004395 67.0
HKD1_k127_5101382_28 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000006896 62.0
HKD1_k127_5101382_3 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 422.0
HKD1_k127_5101382_4 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 409.0
HKD1_k127_5101382_5 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 399.0
HKD1_k127_5101382_6 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 389.0
HKD1_k127_5101382_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K05296 - 1.1.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 332.0
HKD1_k127_5101382_8 Protein conserved in bacteria K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 317.0
HKD1_k127_5101382_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000295 283.0
HKD1_k127_5106734_0 Biotin carboxylase - - - 1.507e-254 812.0
HKD1_k127_5106734_1 (ABC) transporter K02471 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 5.14e-221 700.0
HKD1_k127_5106734_10 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001524 283.0
HKD1_k127_5106734_11 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009475 253.0
HKD1_k127_5106734_12 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000001701 241.0
HKD1_k127_5106734_13 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001458 239.0
HKD1_k127_5106734_14 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008813 252.0
HKD1_k127_5106734_15 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
HKD1_k127_5106734_16 Hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000003239 224.0
HKD1_k127_5106734_17 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000001825 207.0
HKD1_k127_5106734_18 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000003656 177.0
HKD1_k127_5106734_19 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000001845 171.0
HKD1_k127_5106734_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01210 - 3.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 540.0
HKD1_k127_5106734_20 - - - - 0.00000000000000000000000000000000000003038 165.0
HKD1_k127_5106734_21 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000001366 100.0
HKD1_k127_5106734_22 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000001625 93.0
HKD1_k127_5106734_24 - - - - 0.0000000000000001901 94.0
HKD1_k127_5106734_25 - - - - 0.000000000000004924 82.0
HKD1_k127_5106734_26 - - - - 0.0000001818 61.0
HKD1_k127_5106734_27 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000009385 59.0
HKD1_k127_5106734_28 von Willebrand factor type A domain - - - 0.0003319 53.0
HKD1_k127_5106734_3 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 471.0
HKD1_k127_5106734_4 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 442.0
HKD1_k127_5106734_5 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 423.0
HKD1_k127_5106734_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 416.0
HKD1_k127_5106734_7 Acyl-CoA dehydrogenase type 2 domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 371.0
HKD1_k127_5106734_8 Steryl acetyl hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 308.0
HKD1_k127_5106734_9 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 301.0
HKD1_k127_5116137_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1067.0
HKD1_k127_5116137_1 enoyl-CoA hydratase isomerase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 374.0
HKD1_k127_5116137_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003286 254.0
HKD1_k127_5116137_3 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000002919 226.0
HKD1_k127_5116137_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000006802 214.0
HKD1_k127_5116137_5 peptidase activity - - - 0.00000000000000000000000000000000000000000001077 173.0
HKD1_k127_5116137_6 Outer membrane efflux protein - - - 0.000000000000000000000000000000000001279 160.0
HKD1_k127_5116137_7 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000001201 152.0
HKD1_k127_5116137_8 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.00000000000000000000000125 113.0
HKD1_k127_5116137_9 Thrombospondin type 3 repeat - - - 0.0000000001334 76.0
HKD1_k127_515767_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1015.0
HKD1_k127_515767_1 Flavin-binding monooxygenase-like - - - 3.391e-291 903.0
HKD1_k127_515767_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 540.0
HKD1_k127_515767_11 Bacterial regulatory protein, Fis family K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 561.0
HKD1_k127_515767_12 Fungalysin/Thermolysin Propeptide Motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 553.0
HKD1_k127_515767_13 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 508.0
HKD1_k127_515767_14 Ecdysteroid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 487.0
HKD1_k127_515767_15 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 460.0
HKD1_k127_515767_16 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 441.0
HKD1_k127_515767_17 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 419.0
HKD1_k127_515767_18 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 422.0
HKD1_k127_515767_19 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 366.0
HKD1_k127_515767_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 9.308e-279 865.0
HKD1_k127_515767_20 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 355.0
HKD1_k127_515767_21 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 371.0
HKD1_k127_515767_22 Repeat of Unknown Function (DUF347) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 343.0
HKD1_k127_515767_23 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 331.0
HKD1_k127_515767_24 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 336.0
HKD1_k127_515767_25 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
HKD1_k127_515767_26 Helix-hairpin-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 305.0
HKD1_k127_515767_27 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 298.0
HKD1_k127_515767_28 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 294.0
HKD1_k127_515767_29 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 292.0
HKD1_k127_515767_3 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 8.614e-243 767.0
HKD1_k127_515767_30 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002869 294.0
HKD1_k127_515767_31 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 273.0
HKD1_k127_515767_32 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008426 262.0
HKD1_k127_515767_33 COG2513 PEP phosphonomutase and related enzymes K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 280.0
HKD1_k127_515767_34 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005118 256.0
HKD1_k127_515767_35 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003543 263.0
HKD1_k127_515767_36 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008758 250.0
HKD1_k127_515767_37 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004118 255.0
HKD1_k127_515767_38 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000002594 233.0
HKD1_k127_515767_39 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000006834 240.0
HKD1_k127_515767_4 Sulfate transporter antisigma-factor antagonist STAS - - - 4.549e-209 676.0
HKD1_k127_515767_40 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000001196 229.0
HKD1_k127_515767_41 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000002836 233.0
HKD1_k127_515767_42 TIGRFAM conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008005 232.0
HKD1_k127_515767_43 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000008635 243.0
HKD1_k127_515767_44 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000002223 219.0
HKD1_k127_515767_45 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000002769 224.0
HKD1_k127_515767_46 Peptidase M15 - - - 0.0000000000000000000000000000000000000000000000000000000000006254 227.0
HKD1_k127_515767_47 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000003512 223.0
HKD1_k127_515767_48 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000006189 224.0
HKD1_k127_515767_49 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000004605 218.0
HKD1_k127_515767_5 GTP-binding protein TypA K06207 - - 2.434e-207 661.0
HKD1_k127_515767_50 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000001273 214.0
HKD1_k127_515767_51 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000003247 204.0
HKD1_k127_515767_52 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000008714 194.0
HKD1_k127_515767_53 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000003475 195.0
HKD1_k127_515767_54 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000002465 207.0
HKD1_k127_515767_55 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000005031 191.0
HKD1_k127_515767_56 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000008947 191.0
HKD1_k127_515767_57 Serine aminopeptidase, S33 K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000003487 198.0
HKD1_k127_515767_58 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000108 187.0
HKD1_k127_515767_59 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000004953 172.0
HKD1_k127_515767_6 PFAM AMP-dependent synthetase and ligase K00666,K20034 - 6.2.1.44 4.034e-196 626.0
HKD1_k127_515767_60 Haem-binding domain - - - 0.0000000000000000000000000000000000000000001248 165.0
HKD1_k127_515767_61 Limonene-1,2-epoxide hydrolase K10533 - 3.3.2.8 0.0000000000000000000000000000000000000001181 166.0
HKD1_k127_515767_62 - - - - 0.000000000000000000000000000000000000004074 149.0
HKD1_k127_515767_63 FeS assembly SUF system protein - - - 0.000000000000000000000000000000000005219 138.0
HKD1_k127_515767_64 subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000007985 154.0
HKD1_k127_515767_65 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000000000008466 137.0
HKD1_k127_515767_66 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000007396 132.0
HKD1_k127_515767_67 Fibronectin type 3 domain K01179,K06882 - 3.2.1.4 0.0000000000000000000000000000003269 138.0
HKD1_k127_515767_69 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000002348 135.0
HKD1_k127_515767_7 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 617.0
HKD1_k127_515767_70 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000006424 126.0
HKD1_k127_515767_71 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000004564 118.0
HKD1_k127_515767_72 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000009747 122.0
HKD1_k127_515767_73 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.000000000000000000000002086 113.0
HKD1_k127_515767_74 COG0695 Glutaredoxin and related proteins - - - 0.00000000000000000003638 92.0
HKD1_k127_515767_75 META domain K03668 - - 0.00000000000008337 79.0
HKD1_k127_515767_77 Domain of unknown function (DUF4345) - - - 0.000002008 57.0
HKD1_k127_515767_78 - - - - 0.000004529 52.0
HKD1_k127_515767_8 HAMP domain K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 591.0
HKD1_k127_515767_80 F subunit of K+-transporting ATPase (Potass_KdpF) - - - 0.0002532 48.0
HKD1_k127_515767_81 pathogenesis K01337,K04771,K20276,K21449 - 3.4.21.107,3.4.21.50 0.0008612 50.0
HKD1_k127_515767_9 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 546.0
HKD1_k127_5196271_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 1.447e-265 848.0
HKD1_k127_5196271_1 drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 462.0
HKD1_k127_5196271_10 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001653 276.0
HKD1_k127_5196271_11 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000006569 241.0
HKD1_k127_5196271_12 Secretion protein, HlyD K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000001067 243.0
HKD1_k127_5196271_13 Domain of unknown function (DUF1929) - - - 0.00000000000000000000000000000000000000000000000000001566 201.0
HKD1_k127_5196271_14 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.0000000000000000000000000000000000000000000000000001869 189.0
HKD1_k127_5196271_15 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000001893 204.0
HKD1_k127_5196271_16 Arylsulfatase - - - 0.00000000000000000000000000000000000000000000000000463 209.0
HKD1_k127_5196271_17 translation release factor activity - - - 0.000000000000000000000000000000000000000004201 169.0
HKD1_k127_5196271_18 transcriptional regulator - - - 0.00000000000000000000000000000000000007652 150.0
HKD1_k127_5196271_19 carboxylic ester hydrolase activity K08680 - 4.2.99.20 0.00000000000000000000000000000000004388 152.0
HKD1_k127_5196271_2 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 443.0
HKD1_k127_5196271_20 Inorganic pyrophosphatase K15986 - 3.6.1.1 0.0000000000000000000000000000004843 140.0
HKD1_k127_5196271_21 Inorganic pyrophosphatase K15986 - 3.6.1.1 0.000000000000000000000000003286 124.0
HKD1_k127_5196271_22 Protein of unknown function (DUF1329) - - - 0.000000000000000000003835 108.0
HKD1_k127_5196271_23 Bacterial regulatory proteins, tetR family - - - 0.0000000000000002424 94.0
HKD1_k127_5196271_24 PFAM Sulfatase - - - 0.0000000000009871 68.0
HKD1_k127_5196271_25 - - - - 0.0000000001356 74.0
HKD1_k127_5196271_3 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 369.0
HKD1_k127_5196271_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 325.0
HKD1_k127_5196271_5 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 317.0
HKD1_k127_5196271_6 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 298.0
HKD1_k127_5196271_7 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 306.0
HKD1_k127_5196271_8 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004489 273.0
HKD1_k127_5196271_9 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005412 279.0
HKD1_k127_531259_0 regulation of DNA-templated transcription, elongation - - - 2.071e-243 786.0
HKD1_k127_531259_1 TrkA-C domain K03455 - - 1.394e-217 695.0
HKD1_k127_531259_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 334.0
HKD1_k127_531259_11 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 298.0
HKD1_k127_531259_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00076 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003973 283.0
HKD1_k127_531259_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003917 295.0
HKD1_k127_531259_14 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006321 278.0
HKD1_k127_531259_15 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001963 280.0
HKD1_k127_531259_16 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006265 239.0
HKD1_k127_531259_17 alcohol dehydrogenase (NADP+) activity K01081,K11161,K11162 GO:0001523,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0008106,GO:0008150,GO:0008152,GO:0009987,GO:0010817,GO:0012505,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0031984,GO:0034308,GO:0034754,GO:0042175,GO:0042445,GO:0042572,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0052650,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0098827,GO:1901615 1.1.1.300,3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000001492 242.0
HKD1_k127_531259_18 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000009861 215.0
HKD1_k127_531259_19 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000009108 228.0
HKD1_k127_531259_2 DNA polymerase beta thumb K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 616.0
HKD1_k127_531259_20 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000001317 206.0
HKD1_k127_531259_21 PFAM Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000009899 210.0
HKD1_k127_531259_22 - - - - 0.00000000000000000000000000000000000000000000000000000007812 213.0
HKD1_k127_531259_23 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000002739 202.0
HKD1_k127_531259_24 Unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000002704 216.0
HKD1_k127_531259_25 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000003293 193.0
HKD1_k127_531259_26 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000001277 195.0
HKD1_k127_531259_27 repeat protein - - - 0.000000000000000000000000000000000000000000000000195 203.0
HKD1_k127_531259_28 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000491 202.0
HKD1_k127_531259_29 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000001095 173.0
HKD1_k127_531259_3 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 512.0
HKD1_k127_531259_30 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000005219 160.0
HKD1_k127_531259_31 DoxX-like family - - - 0.00000000000000000000000000000000000000001153 157.0
HKD1_k127_531259_32 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000001856 145.0
HKD1_k127_531259_33 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000002661 135.0
HKD1_k127_531259_34 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000004853 128.0
HKD1_k127_531259_35 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000001734 141.0
HKD1_k127_531259_36 Domain of unknown function (DUF4410) - - - 0.00000000000000000000000000001678 126.0
HKD1_k127_531259_37 C-terminal domain of CHU protein family K21449 - - 0.00000000000000000000000000002786 136.0
HKD1_k127_531259_38 - - - - 0.0000000000000000000004616 99.0
HKD1_k127_531259_39 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000005991 112.0
HKD1_k127_531259_4 Phosphate acyltransferases K15781 - 2.3.1.51,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 475.0
HKD1_k127_531259_40 repeat protein - - - 0.000000000000000000002467 111.0
HKD1_k127_531259_41 Biopolymer transport protein K03559 - - 0.00000000000000000003142 99.0
HKD1_k127_531259_42 Thrombospondin type 3 repeat - - - 0.0000000000000001401 91.0
HKD1_k127_531259_43 - - - - 0.000000000000003267 84.0
HKD1_k127_531259_44 Anti-sigma-K factor rskA - - - 0.0000000004977 72.0
HKD1_k127_531259_45 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00004146 55.0
HKD1_k127_531259_46 EF-hand, calcium binding motif - - - 0.0005985 51.0
HKD1_k127_531259_5 PFAM Mammalian cell entry related domain protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 439.0
HKD1_k127_531259_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 407.0
HKD1_k127_531259_7 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 346.0
HKD1_k127_531259_8 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 373.0
HKD1_k127_531259_9 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 317.0
HKD1_k127_531333_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.938e-244 766.0
HKD1_k127_531333_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.682e-240 761.0
HKD1_k127_531333_10 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000002582 174.0
HKD1_k127_531333_11 ubiquinone biosynthetic process - - - 0.000000000000000000000000000000000106 145.0
HKD1_k127_531333_12 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000000000000000000001034 143.0
HKD1_k127_531333_13 Pfam Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000002815 125.0
HKD1_k127_531333_14 Yqey-like protein K09117 - - 0.0000000000000000000000009359 110.0
HKD1_k127_531333_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000009503 79.0
HKD1_k127_531333_16 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000003005 54.0
HKD1_k127_531333_2 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 535.0
HKD1_k127_531333_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 519.0
HKD1_k127_531333_4 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 457.0
HKD1_k127_531333_5 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 308.0
HKD1_k127_531333_6 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003369 267.0
HKD1_k127_531333_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001761 254.0
HKD1_k127_531333_8 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000004185 226.0
HKD1_k127_531333_9 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000002759 218.0
HKD1_k127_5340403_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 497.0
HKD1_k127_5340403_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 468.0
HKD1_k127_5340403_10 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005074 263.0
HKD1_k127_5340403_11 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000002795 201.0
HKD1_k127_5340403_12 EamA-like transporter family K08978 - - 0.00000000000000000000000000000000000000000000000000213 185.0
HKD1_k127_5340403_13 Cupin domain - - - 0.00000000000000000000000000000000000000000000008667 190.0
HKD1_k127_5340403_14 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000004806 172.0
HKD1_k127_5340403_15 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000004994 161.0
HKD1_k127_5340403_16 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000339 139.0
HKD1_k127_5340403_17 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000004211 129.0
HKD1_k127_5340403_18 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000005341 123.0
HKD1_k127_5340403_19 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000001589 105.0
HKD1_k127_5340403_2 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 465.0
HKD1_k127_5340403_20 acyl-CoA dehydrogenase K00249,K07545 - 1.3.8.3,1.3.8.7 0.00000000000000000000006747 111.0
HKD1_k127_5340403_21 - - - - 0.000000000000000000006403 96.0
HKD1_k127_5340403_22 Forkhead associated domain - - - 0.0000000000008622 74.0
HKD1_k127_5340403_23 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000003705 60.0
HKD1_k127_5340403_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 391.0
HKD1_k127_5340403_4 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 375.0
HKD1_k127_5340403_5 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 348.0
HKD1_k127_5340403_6 Acyl-CoA dehydrogenase, type 2, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 358.0
HKD1_k127_5340403_7 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 331.0
HKD1_k127_5340403_8 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 325.0
HKD1_k127_5340403_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004051 274.0
HKD1_k127_5373437_0 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K14447 - 5.4.99.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 503.0
HKD1_k127_5373437_1 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005816 301.0
HKD1_k127_5373437_2 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000001113 244.0
HKD1_k127_5373437_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000002654 203.0
HKD1_k127_5373437_4 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000002627 193.0
HKD1_k127_5427461_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1128.0
HKD1_k127_5427461_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 610.0
HKD1_k127_5427461_10 Acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 401.0
HKD1_k127_5427461_11 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 398.0
HKD1_k127_5427461_12 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 388.0
HKD1_k127_5427461_13 COG1228 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 396.0
HKD1_k127_5427461_14 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 356.0
HKD1_k127_5427461_15 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 372.0
HKD1_k127_5427461_16 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 314.0
HKD1_k127_5427461_17 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001315 276.0
HKD1_k127_5427461_18 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006025 263.0
HKD1_k127_5427461_19 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000003834 239.0
HKD1_k127_5427461_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 596.0
HKD1_k127_5427461_20 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000163 232.0
HKD1_k127_5427461_21 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000009755 222.0
HKD1_k127_5427461_22 Phytanoyl-CoA dioxygenase (PhyH) K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.000000000000000000000000000000000001893 150.0
HKD1_k127_5427461_23 signal sequence binding K03619 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.00000000000000000000000000001731 134.0
HKD1_k127_5427461_24 Hsp20/alpha crystallin family - - - 0.000000000000000000000001081 108.0
HKD1_k127_5427461_25 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000001494 111.0
HKD1_k127_5427461_26 Hsp20/alpha crystallin family - - - 0.0000000000000000000002534 103.0
HKD1_k127_5427461_27 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000024 105.0
HKD1_k127_5427461_28 Sigma-70, region 4 K03088 - - 0.0000000000000000004221 94.0
HKD1_k127_5427461_29 Phospholipid methyltransferase - - - 0.0000000000000000005619 96.0
HKD1_k127_5427461_3 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 591.0
HKD1_k127_5427461_30 serine threonine protein kinase - - - 0.0000000000000002417 93.0
HKD1_k127_5427461_31 Sel1-like repeats. - - - 0.00000000000001301 81.0
HKD1_k127_5427461_32 SCP-2 sterol transfer family - - - 0.00003267 57.0
HKD1_k127_5427461_33 - - - - 0.0007477 48.0
HKD1_k127_5427461_4 Fumarate reductase flavoprotein C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 548.0
HKD1_k127_5427461_5 56kDa selenium binding protein (SBP56) K17285 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 549.0
HKD1_k127_5427461_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 453.0
HKD1_k127_5427461_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 450.0
HKD1_k127_5427461_8 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 442.0
HKD1_k127_5427461_9 beta-N-acetylhexosaminidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 446.0
HKD1_k127_5441466_0 Fatty acid cis/trans isomerase (CTI) - - - 5.049e-201 655.0
HKD1_k127_5441466_1 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 296.0
HKD1_k127_5441466_2 STAS-like domain of unknown function (DUF4325) - - - 0.000000000000000000000000000000000000000000000000000001885 204.0
HKD1_k127_5441466_3 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.00000000000000000000000000000000000000000000000003161 184.0
HKD1_k127_5441466_4 Short-chain dehydrogenase reductase SDR K00046,K00059 - 1.1.1.100,1.1.1.69 0.000000000000000000000000000000000000000000000000183 199.0
HKD1_k127_546517_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 556.0
HKD1_k127_546517_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 494.0
HKD1_k127_546517_10 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000396 143.0
HKD1_k127_546517_12 PFAM Tetratricopeptide - - - 0.0001413 55.0
HKD1_k127_546517_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 491.0
HKD1_k127_546517_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 424.0
HKD1_k127_546517_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 378.0
HKD1_k127_546517_5 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 311.0
HKD1_k127_546517_6 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
HKD1_k127_546517_7 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000001074 291.0
HKD1_k127_546517_8 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000002302 214.0
HKD1_k127_546517_9 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000004089 171.0
HKD1_k127_5503915_0 Protein of unknown function (DUF3141) - - - 1.426e-283 892.0
HKD1_k127_5503915_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.609e-240 752.0
HKD1_k127_5503915_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003199 294.0
HKD1_k127_5503915_11 - - - - 0.00000000000000000000000000000000000000000000000000007256 190.0
HKD1_k127_5503915_12 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000001445 205.0
HKD1_k127_5503915_13 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000001087 174.0
HKD1_k127_5503915_14 Glycine-zipper domain - - - 0.0000000000000000000000000000000001026 143.0
HKD1_k127_5503915_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000001822 151.0
HKD1_k127_5503915_16 AIG2-like family - - - 0.000000000000000000000002554 119.0
HKD1_k127_5503915_17 - - - - 0.00000000000000000001009 98.0
HKD1_k127_5503915_19 - - - - 0.000000000000001677 82.0
HKD1_k127_5503915_2 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 444.0
HKD1_k127_5503915_20 ErfK YbiS YcfS YnhG family protein - - - 0.00000004243 62.0
HKD1_k127_5503915_21 - - - - 0.0000007966 61.0
HKD1_k127_5503915_22 Evidence 5 No homology to any previously reported sequences - - - 0.0001479 55.0
HKD1_k127_5503915_3 copper resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 380.0
HKD1_k127_5503915_4 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 381.0
HKD1_k127_5503915_5 NADPH quinone reductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 387.0
HKD1_k127_5503915_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 353.0
HKD1_k127_5503915_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 348.0
HKD1_k127_5503915_8 secondary active sulfate transmembrane transporter activity K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 317.0
HKD1_k127_5503915_9 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
HKD1_k127_5641810_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 544.0
HKD1_k127_5641810_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 506.0
HKD1_k127_5641810_10 Thioredoxin K03671 - - 0.0000000000000000000000000005015 132.0
HKD1_k127_5641810_11 Cytochrome C assembly protein - - - 0.00000000000001423 87.0
HKD1_k127_5641810_12 domain protein K01081,K01347,K07004,K13735,K17624,K20276 - 3.1.3.5,3.2.1.97,3.4.21.72 0.000000000001063 79.0
HKD1_k127_5641810_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 323.0
HKD1_k127_5641810_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000002465 290.0
HKD1_k127_5641810_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000003313 284.0
HKD1_k127_5641810_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000001124 268.0
HKD1_k127_5641810_6 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000004358 203.0
HKD1_k127_5641810_7 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000001422 176.0
HKD1_k127_5641810_8 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000005172 158.0
HKD1_k127_5641810_9 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000005262 139.0
HKD1_k127_5705099_0 - - - - 0.0 1056.0
HKD1_k127_5705099_1 DNA topoisomerase K02622 - - 2.797e-245 781.0
HKD1_k127_5705099_10 - - - - 0.0000000000000000000000000000001208 129.0
HKD1_k127_5705099_11 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000002612 83.0
HKD1_k127_5705099_2 Belongs to the type II topoisomerase GyrA ParC subunit family K02469,K02621 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 610.0
HKD1_k127_5705099_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 348.0
HKD1_k127_5705099_4 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 334.0
HKD1_k127_5705099_5 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 331.0
HKD1_k127_5705099_6 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002996 218.0
HKD1_k127_5705099_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000006286 200.0
HKD1_k127_5705099_8 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000000000000000000000000000000007723 176.0
HKD1_k127_5705099_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000001848 169.0
HKD1_k127_5716039_0 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1327.0
HKD1_k127_5716039_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1105.0
HKD1_k127_5716039_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 349.0
HKD1_k127_5716039_11 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 323.0
HKD1_k127_5716039_12 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001858 305.0
HKD1_k127_5716039_13 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003441 265.0
HKD1_k127_5716039_14 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000004994 199.0
HKD1_k127_5716039_15 Bacterial type II/III secretion system short domain K02453 - - 0.00000000000000000000000000000000000000000000000000003059 212.0
HKD1_k127_5716039_16 Smr domain - - - 0.0000000000000000000000000000000000000003523 156.0
HKD1_k127_5716039_17 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000007367 154.0
HKD1_k127_5716039_18 - - - - 0.000000000000000000004502 108.0
HKD1_k127_5716039_19 Glyoxalase-like domain - - - 0.00000000000001949 78.0
HKD1_k127_5716039_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.48e-277 889.0
HKD1_k127_5716039_20 Domain of unknown function (DUF4266) - - - 0.00000002188 61.0
HKD1_k127_5716039_21 Type II secretion system protein C - - - 0.0000005113 61.0
HKD1_k127_5716039_22 MotA/TolQ/ExbB proton channel family - - - 0.000004227 56.0
HKD1_k127_5716039_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 499.0
HKD1_k127_5716039_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 520.0
HKD1_k127_5716039_5 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 489.0
HKD1_k127_5716039_6 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 461.0
HKD1_k127_5716039_7 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 417.0
HKD1_k127_5716039_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 403.0
HKD1_k127_5716039_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 379.0
HKD1_k127_5816334_0 Domain of unknown function (DUF3459) K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 575.0
HKD1_k127_5816334_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 455.0
HKD1_k127_5816334_10 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000002445 263.0
HKD1_k127_5816334_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000005075 250.0
HKD1_k127_5816334_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003519 259.0
HKD1_k127_5816334_13 histidine biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003335 248.0
HKD1_k127_5816334_14 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000126 222.0
HKD1_k127_5816334_15 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002215 213.0
HKD1_k127_5816334_16 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000005764 156.0
HKD1_k127_5816334_17 pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000788 122.0
HKD1_k127_5816334_18 methyltransferase activity - - - 0.0000000000000000000000000004453 126.0
HKD1_k127_5816334_19 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000009975 109.0
HKD1_k127_5816334_2 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 460.0
HKD1_k127_5816334_20 Outer membrane lipoprotein-sorting protein - - - 0.0000000000001548 81.0
HKD1_k127_5816334_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000002248 78.0
HKD1_k127_5816334_22 - - - - 0.000000000002647 80.0
HKD1_k127_5816334_23 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000009563 73.0
HKD1_k127_5816334_24 - - - - 0.0001331 52.0
HKD1_k127_5816334_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 426.0
HKD1_k127_5816334_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 392.0
HKD1_k127_5816334_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 331.0
HKD1_k127_5816334_6 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 331.0
HKD1_k127_5816334_7 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 302.0
HKD1_k127_5816334_8 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001027 279.0
HKD1_k127_5816334_9 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002737 293.0
HKD1_k127_5952093_0 Rieske [2Fe-2S] domain - - - 1.246e-195 617.0
HKD1_k127_5952093_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.109e-195 621.0
HKD1_k127_5952093_10 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 355.0
HKD1_k127_5952093_11 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004679 304.0
HKD1_k127_5952093_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000008401 198.0
HKD1_k127_5952093_13 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000008756 181.0
HKD1_k127_5952093_14 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000007154 141.0
HKD1_k127_5952093_15 negative regulation of transcription, DNA-templated - - - 0.000000000000001025 91.0
HKD1_k127_5952093_16 Na H antiporter K03316 - - 0.0001537 56.0
HKD1_k127_5952093_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 8.322e-195 643.0
HKD1_k127_5952093_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 566.0
HKD1_k127_5952093_4 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 572.0
HKD1_k127_5952093_5 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 515.0
HKD1_k127_5952093_6 Oxidoreductase family, C-terminal alpha/beta domain K18067 - 1.3.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 424.0
HKD1_k127_5952093_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 408.0
HKD1_k127_5952093_8 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 398.0
HKD1_k127_5952093_9 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 395.0
HKD1_k127_5967172_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.483e-287 902.0
HKD1_k127_5967172_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.036e-251 782.0
HKD1_k127_5967172_10 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 312.0
HKD1_k127_5967172_11 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 302.0
HKD1_k127_5967172_12 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003096 285.0
HKD1_k127_5967172_13 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001549 274.0
HKD1_k127_5967172_14 amino acid activation for nonribosomal peptide biosynthetic process K14379 - 3.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000002232 262.0
HKD1_k127_5967172_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000006493 242.0
HKD1_k127_5967172_16 Glucose inhibited division protein A - - - 0.000000000000000000000000000000000000000000000000000000003333 217.0
HKD1_k127_5967172_17 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000000000000000008948 211.0
HKD1_k127_5967172_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000002234 189.0
HKD1_k127_5967172_19 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000004748 200.0
HKD1_k127_5967172_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 522.0
HKD1_k127_5967172_20 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000008496 170.0
HKD1_k127_5967172_21 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000001574 181.0
HKD1_k127_5967172_22 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 - - 0.00000000000000000000000000000000000000004758 164.0
HKD1_k127_5967172_23 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000119 153.0
HKD1_k127_5967172_24 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000001193 134.0
HKD1_k127_5967172_25 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000009558 133.0
HKD1_k127_5967172_26 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768,K02769,K02770,K02806 - 2.7.1.202 0.0000000000000000000000000000002297 142.0
HKD1_k127_5967172_27 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000005365 135.0
HKD1_k127_5967172_28 sterol carrier protein - - - 0.00000000000000000000006215 103.0
HKD1_k127_5967172_29 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000003496 106.0
HKD1_k127_5967172_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 507.0
HKD1_k127_5967172_30 phosphoenolpyruvate-dependent sugar phosphotransferase system K02784,K08485,K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000003582 96.0
HKD1_k127_5967172_31 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000001583 93.0
HKD1_k127_5967172_32 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000006143 82.0
HKD1_k127_5967172_33 YsiA-like protein, C-terminal region K13770 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000001351 77.0
HKD1_k127_5967172_34 aspartic-type endopeptidase activity K06985 - - 0.0000006876 61.0
HKD1_k127_5967172_35 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000002759 55.0
HKD1_k127_5967172_36 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0009913 49.0
HKD1_k127_5967172_4 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 478.0
HKD1_k127_5967172_5 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 454.0
HKD1_k127_5967172_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 455.0
HKD1_k127_5967172_7 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 401.0
HKD1_k127_5967172_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 376.0
HKD1_k127_5967172_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 333.0
HKD1_k127_604791_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 523.0
HKD1_k127_604791_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 414.0
HKD1_k127_604791_10 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000001853 260.0
HKD1_k127_604791_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000009483 221.0
HKD1_k127_604791_12 - - - - 0.000000000000000000000000000000000000000000002404 188.0
HKD1_k127_604791_13 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000002747 166.0
HKD1_k127_604791_14 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000001228 160.0
HKD1_k127_604791_15 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000002983 143.0
HKD1_k127_604791_16 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000002262 125.0
HKD1_k127_604791_17 Jacalin-like lectin domain - - - 0.0000000000000000000000000000427 126.0
HKD1_k127_604791_18 sequence-specific DNA binding - - - 0.000000000000000101 92.0
HKD1_k127_604791_19 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000007087 88.0
HKD1_k127_604791_2 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 430.0
HKD1_k127_604791_3 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 393.0
HKD1_k127_604791_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 361.0
HKD1_k127_604791_5 COG0695 glutaredoxin and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 339.0
HKD1_k127_604791_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 308.0
HKD1_k127_604791_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
HKD1_k127_604791_8 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000366 273.0
HKD1_k127_604791_9 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001947 277.0
HKD1_k127_6083003_0 Cytochrome C and Quinol oxidase polypeptide I - - - 1.266e-247 788.0
HKD1_k127_6083003_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 627.0
HKD1_k127_6083003_10 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00381,K00392 GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0020037,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0097159,GO:1901363 1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 346.0
HKD1_k127_6083003_11 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 301.0
HKD1_k127_6083003_12 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 310.0
HKD1_k127_6083003_13 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 264.0
HKD1_k127_6083003_14 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 252.0
HKD1_k127_6083003_15 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000004418 230.0
HKD1_k127_6083003_16 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000002684 188.0
HKD1_k127_6083003_17 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000003323 169.0
HKD1_k127_6083003_18 Phospholipid N-methyltransferase - - - 0.00000000000000000000000000000000000000000002014 169.0
HKD1_k127_6083003_19 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000008223 168.0
HKD1_k127_6083003_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 529.0
HKD1_k127_6083003_20 Cytochrome c - - - 0.000000000000000000000000000000000000000001016 175.0
HKD1_k127_6083003_21 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000002438 151.0
HKD1_k127_6083003_22 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000002695 160.0
HKD1_k127_6083003_23 electron K07152 - - 0.0000000000000000000000000000000000001856 152.0
HKD1_k127_6083003_24 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000006629 147.0
HKD1_k127_6083003_25 EVE domain - - - 0.000000000000000000000000000000009361 143.0
HKD1_k127_6083003_26 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000001939 131.0
HKD1_k127_6083003_27 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000007107 134.0
HKD1_k127_6083003_28 Translation initiation factor K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000008701 126.0
HKD1_k127_6083003_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000003345 103.0
HKD1_k127_6083003_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 458.0
HKD1_k127_6083003_30 FCD K05799 - - 0.000000000000000006712 93.0
HKD1_k127_6083003_31 SURF1 family K14998 - - 0.00000000000000001962 96.0
HKD1_k127_6083003_32 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000105 82.0
HKD1_k127_6083003_34 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000001598 69.0
HKD1_k127_6083003_4 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 486.0
HKD1_k127_6083003_5 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 405.0
HKD1_k127_6083003_6 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 405.0
HKD1_k127_6083003_7 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 391.0
HKD1_k127_6083003_8 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 344.0
HKD1_k127_6083003_9 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 346.0
HKD1_k127_6103982_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.791e-223 725.0
HKD1_k127_6103982_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 558.0
HKD1_k127_6103982_10 ABC transporter transmembrane region K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 372.0
HKD1_k127_6103982_11 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 349.0
HKD1_k127_6103982_12 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 346.0
HKD1_k127_6103982_13 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 335.0
HKD1_k127_6103982_14 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 300.0
HKD1_k127_6103982_15 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 303.0
HKD1_k127_6103982_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004115 291.0
HKD1_k127_6103982_17 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000001025 281.0
HKD1_k127_6103982_18 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001769 281.0
HKD1_k127_6103982_19 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001841 275.0
HKD1_k127_6103982_2 beta-glucosidase activity K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 520.0
HKD1_k127_6103982_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000007401 263.0
HKD1_k127_6103982_21 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 265.0
HKD1_k127_6103982_22 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002023 248.0
HKD1_k127_6103982_23 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000007949 248.0
HKD1_k127_6103982_24 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000003153 261.0
HKD1_k127_6103982_25 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000005955 235.0
HKD1_k127_6103982_26 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000001027 241.0
HKD1_k127_6103982_27 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000009244 243.0
HKD1_k127_6103982_28 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000001271 222.0
HKD1_k127_6103982_29 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000007694 231.0
HKD1_k127_6103982_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 497.0
HKD1_k127_6103982_30 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000002463 225.0
HKD1_k127_6103982_31 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000005367 220.0
HKD1_k127_6103982_32 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000006308 201.0
HKD1_k127_6103982_33 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000008799 203.0
HKD1_k127_6103982_34 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000001865 183.0
HKD1_k127_6103982_35 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000003736 181.0
HKD1_k127_6103982_36 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000001981 185.0
HKD1_k127_6103982_37 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000002093 162.0
HKD1_k127_6103982_38 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000004842 163.0
HKD1_k127_6103982_39 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000224 147.0
HKD1_k127_6103982_4 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 447.0
HKD1_k127_6103982_40 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000002336 143.0
HKD1_k127_6103982_41 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000003214 140.0
HKD1_k127_6103982_42 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000001348 130.0
HKD1_k127_6103982_43 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000007333 119.0
HKD1_k127_6103982_44 - - - - 0.000000000000000000000001595 121.0
HKD1_k127_6103982_45 Uncharacterized protein family UPF0054 K07042 - - 0.0000000000000000000004438 102.0
HKD1_k127_6103982_46 Belongs to the UPF0296 family K09777 - - 0.000000000000000000001451 107.0
HKD1_k127_6103982_47 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000003198 104.0
HKD1_k127_6103982_48 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000007727 91.0
HKD1_k127_6103982_49 Dolichyl-phosphate-mannose-protein mannosyltransferase K00721 - 2.4.1.83 0.000000000000000006113 99.0
HKD1_k127_6103982_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 443.0
HKD1_k127_6103982_50 DoxX-like family - - - 0.000000000000001044 82.0
HKD1_k127_6103982_51 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.0000000000001847 84.0
HKD1_k127_6103982_52 Trm112p-like protein K09791 - - 0.00000000006049 74.0
HKD1_k127_6103982_53 regulator, PATAN and FRGAF domain-containing - - - 0.000000000938 70.0
HKD1_k127_6103982_54 outer membrane chaperone Skp (OmpH) K06142 - - 0.000000003713 71.0
HKD1_k127_6103982_56 zinc-ribbon domain - - - 0.0000002714 64.0
HKD1_k127_6103982_57 Lipopolysaccharide-assembly - - - 0.0000007096 59.0
HKD1_k127_6103982_58 Aspartyl protease - - - 0.000002433 60.0
HKD1_k127_6103982_59 all-trans-retinol 13,14-reductase activity - - - 0.00002359 57.0
HKD1_k127_6103982_6 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 383.0
HKD1_k127_6103982_60 Binds directly to 16S ribosomal RNA K02968 - - 0.0001153 52.0
HKD1_k127_6103982_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 383.0
HKD1_k127_6103982_8 PCRF K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 384.0
HKD1_k127_6103982_9 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
HKD1_k127_6105298_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 544.0
HKD1_k127_6105298_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 465.0
HKD1_k127_6105298_10 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000004012 161.0
HKD1_k127_6105298_11 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000003623 139.0
HKD1_k127_6105298_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000005723 91.0
HKD1_k127_6105298_13 Heavy-metal resistance - - - 0.0003928 52.0
HKD1_k127_6105298_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 442.0
HKD1_k127_6105298_3 Binding-protein-dependent transport system inner membrane component K02050,K15552,K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 406.0
HKD1_k127_6105298_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 413.0
HKD1_k127_6105298_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 320.0
HKD1_k127_6105298_6 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 315.0
HKD1_k127_6105298_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004017 253.0
HKD1_k127_6105298_8 copper ion homeostasis K07152,K12818 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000458 199.0
HKD1_k127_6105298_9 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000001468 178.0
HKD1_k127_6112268_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1037.0
HKD1_k127_6112268_1 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 627.0
HKD1_k127_6112268_10 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.00000000000000000000000000000000000000006947 168.0
HKD1_k127_6112268_11 ImpA, N-terminal, type VI secretion system K11902 - - 0.000000000000000000000000000000000000001759 162.0
HKD1_k127_6112268_13 beta-ketoacyl-acyl-carrier-protein synthase II activity K00647 - 2.3.1.41 0.0000000000000000000000000000000000204 150.0
HKD1_k127_6112268_15 ImcF-related N-terminal domain K11891 - - 0.00000000000000000000000000000005035 147.0
HKD1_k127_6112268_16 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000004047 117.0
HKD1_k127_6112268_17 Gene 25-like lysozyme K11897 - - 0.00000000000000000004652 96.0
HKD1_k127_6112268_18 Type VI secretion system protein DotU K11892 - - 0.00000000000000005788 89.0
HKD1_k127_6112268_19 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000002701 77.0
HKD1_k127_6112268_2 TIGRFAM type VI secretion protein, EvpB VC_A0108 family K11900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 592.0
HKD1_k127_6112268_20 deoxyhypusine monooxygenase activity - - - 0.000000000647 71.0
HKD1_k127_6112268_21 TIGRFAM type VI secretion lipoprotein, VC_A0113 family K11906 - - 0.000002203 59.0
HKD1_k127_6112268_22 Forkhead associated domain - - - 0.0001084 52.0
HKD1_k127_6112268_3 TIGRFAM type VI secretion protein, VC_A0110 family K11896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 497.0
HKD1_k127_6112268_4 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 338.0
HKD1_k127_6112268_5 Domain of unknown function (DUF4150) - - - 0.0000000000000000000000000000000000000000000000000000000000000009165 237.0
HKD1_k127_6112268_6 TIGRFAM type VI secretion protein, VC_A0111 family K11895 - - 0.0000000000000000000000000000000000000000000000000000002153 222.0
HKD1_k127_6112268_7 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.000000000000000000000000000000000000000000000000005409 187.0
HKD1_k127_6112268_8 - - - - 0.000000000000000000000000000000000000000000000000437 184.0
HKD1_k127_6112268_9 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.00000000000000000000000000000000000000002364 163.0
HKD1_k127_6117556_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 9.017e-317 979.0
HKD1_k127_6117556_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 313.0
HKD1_k127_6117556_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000001875 171.0
HKD1_k127_6117556_11 - - - - 0.000000000000000000000000000000000009329 143.0
HKD1_k127_6117556_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000009837 141.0
HKD1_k127_6117556_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000003336 119.0
HKD1_k127_6117556_14 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000002312 81.0
HKD1_k127_6117556_15 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.00007231 54.0
HKD1_k127_6117556_2 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005911 278.0
HKD1_k127_6117556_3 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 278.0
HKD1_k127_6117556_4 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000003023 219.0
HKD1_k127_6117556_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000026 214.0
HKD1_k127_6117556_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000004224 204.0
HKD1_k127_6117556_7 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000002089 179.0
HKD1_k127_6117556_8 PFAM Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000001424 178.0
HKD1_k127_6117556_9 very-long-chain-acyl-CoA dehydrogenase activity K00249,K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.8.7 0.000000000000000000000000000000000000000000001792 175.0
HKD1_k127_6141576_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.525e-294 914.0
HKD1_k127_6141576_1 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 2.895e-252 793.0
HKD1_k127_6141576_10 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 368.0
HKD1_k127_6141576_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 366.0
HKD1_k127_6141576_12 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 349.0
HKD1_k127_6141576_13 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 348.0
HKD1_k127_6141576_14 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 362.0
HKD1_k127_6141576_15 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004408 273.0
HKD1_k127_6141576_16 ABC transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005268 282.0
HKD1_k127_6141576_17 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001629 285.0
HKD1_k127_6141576_18 lysozyme activity K07273 - - 0.00000000000000000000000000000000000000000000000000000000000001026 226.0
HKD1_k127_6141576_19 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000006832 210.0
HKD1_k127_6141576_2 Cys Met metabolism pyridoxal-phosphate-dependent enzyme - - - 6.584e-236 743.0
HKD1_k127_6141576_20 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000001068 214.0
HKD1_k127_6141576_21 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000001135 201.0
HKD1_k127_6141576_22 PFAM MaoC domain protein dehydratase K14449 - 4.2.1.148 0.000000000000000000000000000000000000000000000000003865 195.0
HKD1_k127_6141576_23 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000007638 195.0
HKD1_k127_6141576_24 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000001979 192.0
HKD1_k127_6141576_25 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000002176 195.0
HKD1_k127_6141576_26 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000000128 156.0
HKD1_k127_6141576_27 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000002966 161.0
HKD1_k127_6141576_28 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000006507 162.0
HKD1_k127_6141576_29 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000007085 145.0
HKD1_k127_6141576_3 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 611.0
HKD1_k127_6141576_30 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000053 141.0
HKD1_k127_6141576_31 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000001071 141.0
HKD1_k127_6141576_32 Peptidase family M28 - - - 0.000000000000000000000000000001856 137.0
HKD1_k127_6141576_33 - - - - 0.000000000000000000000000002864 115.0
HKD1_k127_6141576_34 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000007175 125.0
HKD1_k127_6141576_35 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000002735 115.0
HKD1_k127_6141576_36 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.000000000000000000003068 99.0
HKD1_k127_6141576_37 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000003083 110.0
HKD1_k127_6141576_38 acetyltransferase K06977 - - 0.0000000000000000002959 99.0
HKD1_k127_6141576_39 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000001732 99.0
HKD1_k127_6141576_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 505.0
HKD1_k127_6141576_40 repeat protein - - - 0.000000000000000002381 99.0
HKD1_k127_6141576_41 Histidine kinase - - - 0.0000000000000004159 89.0
HKD1_k127_6141576_42 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.00000000000002572 86.0
HKD1_k127_6141576_43 AsmA-like C-terminal region - - - 0.00000000000003534 87.0
HKD1_k127_6141576_44 Belongs to the ompA family K03286 - - 0.0000000000001515 79.0
HKD1_k127_6141576_45 Domain of unknown function (DUF4081) K06976 - - 0.0000000000007948 79.0
HKD1_k127_6141576_46 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000009546 57.0
HKD1_k127_6141576_47 transcriptional regulator K07667 - - 0.00000001205 65.0
HKD1_k127_6141576_48 Belongs to the amidase family K01426 - 3.5.1.4 0.00000111 51.0
HKD1_k127_6141576_49 von Willebrand factor (vWF) type A domain - - - 0.0000222 57.0
HKD1_k127_6141576_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 488.0
HKD1_k127_6141576_51 Oxygen tolerance - - - 0.00004889 57.0
HKD1_k127_6141576_52 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0001923 53.0
HKD1_k127_6141576_6 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 460.0
HKD1_k127_6141576_7 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 419.0
HKD1_k127_6141576_8 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 422.0
HKD1_k127_6141576_9 radical SAM domain protein K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 373.0
HKD1_k127_6180908_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.439e-246 780.0
HKD1_k127_6180908_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 387.0
HKD1_k127_6180908_2 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001884 246.0
HKD1_k127_6180908_3 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000001213 198.0
HKD1_k127_6180908_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000008537 185.0
HKD1_k127_6180908_5 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000003652 174.0
HKD1_k127_6180908_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000004422 128.0
HKD1_k127_6180908_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000003877 79.0
HKD1_k127_6180908_8 helix_turn_helix, Lux Regulon - - - 0.000000001272 67.0
HKD1_k127_6180908_9 - - - - 0.0000009601 61.0
HKD1_k127_6298989_0 Methionine synthase K00548 - 2.1.1.13 0.0 1643.0
HKD1_k127_6298989_1 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 0.0 1292.0
HKD1_k127_6298989_10 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000001457 165.0
HKD1_k127_6298989_11 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619 - 1.20.4.1,2.3.1.1 0.000000000000000000000000000000000000003494 168.0
HKD1_k127_6298989_12 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000002479 138.0
HKD1_k127_6298989_13 Protein of unknown function (DUF3313) - - - 0.00000000000000000002077 95.0
HKD1_k127_6298989_14 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.000001104 50.0
HKD1_k127_6298989_15 - K02450 - - 0.000006086 52.0
HKD1_k127_6298989_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 582.0
HKD1_k127_6298989_3 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 589.0
HKD1_k127_6298989_4 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 410.0
HKD1_k127_6298989_5 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 404.0
HKD1_k127_6298989_6 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 390.0
HKD1_k127_6298989_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004085 259.0
HKD1_k127_6298989_8 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000003195 260.0
HKD1_k127_6298989_9 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000003815 214.0
HKD1_k127_63141_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 634.0
HKD1_k127_63141_1 Zn-dependent hydrolases of the beta-lactamase fold K14952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 537.0
HKD1_k127_63141_10 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 363.0
HKD1_k127_63141_11 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 372.0
HKD1_k127_63141_12 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 342.0
HKD1_k127_63141_13 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 331.0
HKD1_k127_63141_14 PFAM alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 347.0
HKD1_k127_63141_15 Belongs to the cytochrome P450 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 299.0
HKD1_k127_63141_16 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004323 306.0
HKD1_k127_63141_17 P COG0025 NhaP-type Na H and K H antiporters K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005078 280.0
HKD1_k127_63141_18 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000005551 219.0
HKD1_k127_63141_19 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
HKD1_k127_63141_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 511.0
HKD1_k127_63141_20 Beta-lactamase class C - - - 0.00000000000000000000000000000000000000000000000000004923 213.0
HKD1_k127_63141_21 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000005864 160.0
HKD1_k127_63141_22 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000003817 168.0
HKD1_k127_63141_23 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000009016 150.0
HKD1_k127_63141_24 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000001272 132.0
HKD1_k127_63141_25 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000001065 130.0
HKD1_k127_63141_26 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000132 113.0
HKD1_k127_63141_27 Parallel beta-helix repeats - - - 0.000000000002001 81.0
HKD1_k127_63141_28 protein domain associated with - - - 0.000000000006178 78.0
HKD1_k127_63141_29 Bacterial regulatory proteins, tetR family - - - 0.000000008995 64.0
HKD1_k127_63141_3 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 511.0
HKD1_k127_63141_30 DNA excision - - - 0.00000005012 58.0
HKD1_k127_63141_31 Beta-propeller repeat - - - 0.000003024 59.0
HKD1_k127_63141_4 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 471.0
HKD1_k127_63141_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 455.0
HKD1_k127_63141_6 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 441.0
HKD1_k127_63141_7 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 386.0
HKD1_k127_63141_8 PFAM CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 400.0
HKD1_k127_63141_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 384.0
HKD1_k127_6423396_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 582.0
HKD1_k127_6423396_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 375.0
HKD1_k127_6423396_10 Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor K00214 GO:0000166,GO:0003674,GO:0003824,GO:0004074,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0019439,GO:0033013,GO:0033015,GO:0034641,GO:0036094,GO:0042167,GO:0042168,GO:0042440,GO:0044237,GO:0044248,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.3.1.24 0.000000000000000000005073 103.0
HKD1_k127_6423396_11 Ribosomal protein L31 K02909 - - 0.000000000000009415 85.0
HKD1_k127_6423396_12 ubiE/COQ5 methyltransferase family - - - 0.000000000001677 77.0
HKD1_k127_6423396_13 SnoaL-like domain - - - 0.000005896 56.0
HKD1_k127_6423396_2 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 343.0
HKD1_k127_6423396_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000007967 259.0
HKD1_k127_6423396_4 o-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000003313 255.0
HKD1_k127_6423396_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002268 268.0
HKD1_k127_6423396_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000009632 175.0
HKD1_k127_6423396_7 branched-chain-amino-acid transaminase activity K00826 - 2.6.1.42 0.000000000000000000000000000000000003676 149.0
HKD1_k127_6423396_8 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000002892 134.0
HKD1_k127_6423396_9 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000008131 109.0
HKD1_k127_6445834_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 466.0
HKD1_k127_6445834_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 466.0
HKD1_k127_6445834_10 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000003451 196.0
HKD1_k127_6445834_11 GrpB protein - - - 0.00000000000000000000000000000000000000000000000646 192.0
HKD1_k127_6445834_12 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000000000966 139.0
HKD1_k127_6445834_13 amine dehydrogenase activity - - - 0.000000000000000000000001065 123.0
HKD1_k127_6445834_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001138 117.0
HKD1_k127_6445834_15 Domain of unknown function (DUF4136) - - - 0.00000000000000000000002225 106.0
HKD1_k127_6445834_18 Dienelactone hydrolase family - - - 0.0003798 55.0
HKD1_k127_6445834_2 PFAM aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 442.0
HKD1_k127_6445834_3 PFAM Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 358.0
HKD1_k127_6445834_4 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 320.0
HKD1_k127_6445834_5 3-isopropylmalate dehydrogenase activity K00052,K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85,1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 306.0
HKD1_k127_6445834_6 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002098 295.0
HKD1_k127_6445834_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005361 270.0
HKD1_k127_6445834_8 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001799 229.0
HKD1_k127_6445834_9 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000004142 226.0
HKD1_k127_6551076_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 529.0
HKD1_k127_6551076_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000001539 204.0
HKD1_k127_6551076_2 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000009499 125.0
HKD1_k127_6551076_3 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000004222 96.0
HKD1_k127_6611242_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.664e-238 759.0
HKD1_k127_6611242_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 559.0
HKD1_k127_6611242_10 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 395.0
HKD1_k127_6611242_11 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 366.0
HKD1_k127_6611242_12 sulfate transport system, permease K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 377.0
HKD1_k127_6611242_13 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 362.0
HKD1_k127_6611242_14 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 366.0
HKD1_k127_6611242_15 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 353.0
HKD1_k127_6611242_16 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 343.0
HKD1_k127_6611242_17 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06136,K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 321.0
HKD1_k127_6611242_18 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 302.0
HKD1_k127_6611242_19 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 312.0
HKD1_k127_6611242_2 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 530.0
HKD1_k127_6611242_20 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000175 285.0
HKD1_k127_6611242_21 Potential Queuosine, Q, salvage protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004011 280.0
HKD1_k127_6611242_22 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 281.0
HKD1_k127_6611242_23 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008222 278.0
HKD1_k127_6611242_24 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003033 282.0
HKD1_k127_6611242_25 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006643 291.0
HKD1_k127_6611242_26 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006751 252.0
HKD1_k127_6611242_27 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000001105 251.0
HKD1_k127_6611242_28 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
HKD1_k127_6611242_29 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000002731 219.0
HKD1_k127_6611242_3 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 516.0
HKD1_k127_6611242_30 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000001452 194.0
HKD1_k127_6611242_31 Beta-lactamase - - - 0.000000000000000000000000000000000000000000001681 179.0
HKD1_k127_6611242_32 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000004986 165.0
HKD1_k127_6611242_33 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000001564 142.0
HKD1_k127_6611242_34 EthD domain - - - 0.00000000000000000000000000002308 138.0
HKD1_k127_6611242_35 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.0000000000000000000000000004379 120.0
HKD1_k127_6611242_36 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000002691 93.0
HKD1_k127_6611242_37 transcriptional regulator, TetR family - - - 0.000000000000000003452 92.0
HKD1_k127_6611242_38 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000001951 72.0
HKD1_k127_6611242_39 Outer membrane lipoprotein-sorting protein - - - 0.000000001847 68.0
HKD1_k127_6611242_4 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 515.0
HKD1_k127_6611242_40 Tetratricopeptide repeat - - - 0.0007206 52.0
HKD1_k127_6611242_5 M18 family aminopeptidase K01267 - 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 477.0
HKD1_k127_6611242_6 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 456.0
HKD1_k127_6611242_7 Sterol-sensing domain of SREBP cleavage-activation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 456.0
HKD1_k127_6611242_8 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 446.0
HKD1_k127_6611242_9 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 387.0
HKD1_k127_6649960_0 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 4.467e-275 867.0
HKD1_k127_6649960_1 ABC-type multidrug transport system ATPase and permease K06147 - - 5.721e-266 833.0
HKD1_k127_6649960_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 411.0
HKD1_k127_6649960_11 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 415.0
HKD1_k127_6649960_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 403.0
HKD1_k127_6649960_13 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 359.0
HKD1_k127_6649960_14 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 348.0
HKD1_k127_6649960_15 COG3264 Small-conductance mechanosensitive channel K22051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 366.0
HKD1_k127_6649960_16 Catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide K03119 GO:0000907,GO:0000908,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0044237,GO:0044248,GO:0044273,GO:0044424,GO:0044464,GO:0051213,GO:0055114 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 335.0
HKD1_k127_6649960_17 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 347.0
HKD1_k127_6649960_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 328.0
HKD1_k127_6649960_19 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 341.0
HKD1_k127_6649960_2 Sulfatase - - - 1.019e-217 695.0
HKD1_k127_6649960_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 327.0
HKD1_k127_6649960_21 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 333.0
HKD1_k127_6649960_22 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 316.0
HKD1_k127_6649960_23 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 289.0
HKD1_k127_6649960_24 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 291.0
HKD1_k127_6649960_25 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 293.0
HKD1_k127_6649960_26 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 306.0
HKD1_k127_6649960_27 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 315.0
HKD1_k127_6649960_28 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003236 288.0
HKD1_k127_6649960_29 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005823 287.0
HKD1_k127_6649960_3 Luciferase-like monooxygenase - - - 2.292e-205 658.0
HKD1_k127_6649960_30 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004511 275.0
HKD1_k127_6649960_31 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007094 294.0
HKD1_k127_6649960_32 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009575 271.0
HKD1_k127_6649960_33 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 263.0
HKD1_k127_6649960_34 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000008251 259.0
HKD1_k127_6649960_35 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009937 261.0
HKD1_k127_6649960_36 PFAM Sulfotransferase K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000001256 248.0
HKD1_k127_6649960_37 MAPEG family - - - 0.000000000000000000000000000000000000000000000000000000000000000007236 227.0
HKD1_k127_6649960_38 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000001634 225.0
HKD1_k127_6649960_39 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000003385 223.0
HKD1_k127_6649960_4 Bacterial protein of unknown function (DUF839) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 613.0
HKD1_k127_6649960_40 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000001733 233.0
HKD1_k127_6649960_41 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000008919 220.0
HKD1_k127_6649960_42 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000006536 199.0
HKD1_k127_6649960_43 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000007627 200.0
HKD1_k127_6649960_44 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000001113 200.0
HKD1_k127_6649960_45 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000001323 193.0
HKD1_k127_6649960_46 PFAM Glutathione S-transferase K11209 - - 0.0000000000000000000000000000000000000000000000000362 197.0
HKD1_k127_6649960_47 Membrane K08984 - - 0.000000000000000000000000000000000000000000000004082 197.0
HKD1_k127_6649960_48 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000001681 179.0
HKD1_k127_6649960_49 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000005915 170.0
HKD1_k127_6649960_5 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 591.0
HKD1_k127_6649960_50 - - - - 0.00000000000000000000000000000000000000000833 170.0
HKD1_k127_6649960_51 dioxygenase activity - - - 0.0000000000000000000000000000000000000005488 159.0
HKD1_k127_6649960_52 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K00561 - 2.1.1.184 0.00000000000000000000000000000000000001143 152.0
HKD1_k127_6649960_53 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000001344 144.0
HKD1_k127_6649960_54 transcriptional regulator - - - 0.0000000000000000000000000000001227 131.0
HKD1_k127_6649960_55 transcriptional regulator - - - 0.00000000000000000000000000001643 125.0
HKD1_k127_6649960_56 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000001878 118.0
HKD1_k127_6649960_57 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000002053 128.0
HKD1_k127_6649960_58 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000005862 119.0
HKD1_k127_6649960_59 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000003094 111.0
HKD1_k127_6649960_6 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 484.0
HKD1_k127_6649960_60 membrane - - - 0.000000000000000000000003245 115.0
HKD1_k127_6649960_61 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000092 109.0
HKD1_k127_6649960_62 Phosphotransferase enzyme family K00899 - 2.7.1.100 0.000000000000000000004055 109.0
HKD1_k127_6649960_63 TfoX N-terminal domain K07343 - - 0.00000000000000000003046 94.0
HKD1_k127_6649960_64 Protein of unknown function (DUF1329) - - - 0.0000000000000000007934 96.0
HKD1_k127_6649960_65 Transcriptional regulatory protein, C terminal - - - 0.000000000000000103 96.0
HKD1_k127_6649960_66 Integrin alpha (beta-propellor repeats). - - - 0.00000000000001332 89.0
HKD1_k127_6649960_67 Parallel beta-helix repeats - - - 0.0000000000002082 85.0
HKD1_k127_6649960_68 - - - - 0.0000000002284 66.0
HKD1_k127_6649960_69 - - - - 0.00000001986 64.0
HKD1_k127_6649960_7 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 467.0
HKD1_k127_6649960_70 Thrombospondin type 3 repeat - - - 0.0000007664 64.0
HKD1_k127_6649960_71 HEAT repeats - - - 0.000004944 56.0
HKD1_k127_6649960_72 Domain of unknown function (DUF4880) - - - 0.00001268 56.0
HKD1_k127_6649960_73 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00002599 49.0
HKD1_k127_6649960_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 432.0
HKD1_k127_6649960_9 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 417.0
HKD1_k127_6670174_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1187.0
HKD1_k127_6670174_1 ABC-type multidrug transport system, ATPase component K13926 - - 0.0 1166.0
HKD1_k127_6670174_10 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 566.0
HKD1_k127_6670174_11 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 552.0
HKD1_k127_6670174_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 529.0
HKD1_k127_6670174_13 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 526.0
HKD1_k127_6670174_14 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 495.0
HKD1_k127_6670174_15 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 445.0
HKD1_k127_6670174_16 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 429.0
HKD1_k127_6670174_17 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 410.0
HKD1_k127_6670174_18 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 409.0
HKD1_k127_6670174_19 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 411.0
HKD1_k127_6670174_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.224e-296 932.0
HKD1_k127_6670174_20 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 412.0
HKD1_k127_6670174_21 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 395.0
HKD1_k127_6670174_22 COG2189 Adenine specific DNA methylase Mod K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 392.0
HKD1_k127_6670174_23 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 385.0
HKD1_k127_6670174_24 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 380.0
HKD1_k127_6670174_25 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 383.0
HKD1_k127_6670174_26 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 377.0
HKD1_k127_6670174_27 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 340.0
HKD1_k127_6670174_28 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 343.0
HKD1_k127_6670174_29 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 321.0
HKD1_k127_6670174_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.013e-280 902.0
HKD1_k127_6670174_30 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 323.0
HKD1_k127_6670174_31 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 302.0
HKD1_k127_6670174_32 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 306.0
HKD1_k127_6670174_33 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 296.0
HKD1_k127_6670174_34 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 292.0
HKD1_k127_6670174_35 COG0845 Membrane-fusion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 293.0
HKD1_k127_6670174_36 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000001362 269.0
HKD1_k127_6670174_37 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000001303 274.0
HKD1_k127_6670174_38 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008415 262.0
HKD1_k127_6670174_39 SIS domain K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000001702 239.0
HKD1_k127_6670174_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.327e-264 837.0
HKD1_k127_6670174_40 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000001627 239.0
HKD1_k127_6670174_41 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000005157 246.0
HKD1_k127_6670174_42 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000003829 242.0
HKD1_k127_6670174_43 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000005139 223.0
HKD1_k127_6670174_44 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000000004014 210.0
HKD1_k127_6670174_45 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000008675 207.0
HKD1_k127_6670174_46 Domain of unknown function (DUF4336) - - - 0.00000000000000000000000000000000000000000000000000000003962 203.0
HKD1_k127_6670174_47 Glycosyl transferases group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000001526 209.0
HKD1_k127_6670174_48 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000002173 212.0
HKD1_k127_6670174_49 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000004045 212.0
HKD1_k127_6670174_5 Sulfatase K01130 - 3.1.6.1 1.188e-230 723.0
HKD1_k127_6670174_50 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000001864 181.0
HKD1_k127_6670174_51 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000004443 166.0
HKD1_k127_6670174_52 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000003014 158.0
HKD1_k127_6670174_53 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000003802 138.0
HKD1_k127_6670174_54 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000043 152.0
HKD1_k127_6670174_55 to the N-terminal domain of Lon protease K07157 - - 0.00000000000000000000000000000005248 133.0
HKD1_k127_6670174_56 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000594 136.0
HKD1_k127_6670174_57 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000675 142.0
HKD1_k127_6670174_58 methyltransferase K21459 - 2.1.1.301 0.00000000000000000000000000002542 126.0
HKD1_k127_6670174_59 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000002788 125.0
HKD1_k127_6670174_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.412e-227 712.0
HKD1_k127_6670174_60 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000001917 119.0
HKD1_k127_6670174_61 Protein of unknown function (DUF1232) - - - 0.000000000000000000000006341 110.0
HKD1_k127_6670174_62 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000001674 115.0
HKD1_k127_6670174_63 - - - - 0.000000000000000000001007 111.0
HKD1_k127_6670174_64 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000001281 104.0
HKD1_k127_6670174_65 signal sequence binding K07152 - - 0.000000000000000000007237 107.0
HKD1_k127_6670174_66 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000002849 97.0
HKD1_k127_6670174_67 - - - - 0.0000000000000000001937 97.0
HKD1_k127_6670174_68 Polymer-forming cytoskeletal - - - 0.000000000000000001111 98.0
HKD1_k127_6670174_69 subfamily IA, variant 1 K20862 - 3.1.3.102,3.1.3.104 0.000000000000000008833 97.0
HKD1_k127_6670174_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.987e-218 697.0
HKD1_k127_6670174_70 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000111 94.0
HKD1_k127_6670174_71 domain, Protein - - - 0.0000000000000002326 87.0
HKD1_k127_6670174_72 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000006097 87.0
HKD1_k127_6670174_73 Acyl-transferase K00655 - 2.3.1.51 0.0000000000001673 84.0
HKD1_k127_6670174_74 YceI-like domain - - - 0.000000000000468 82.0
HKD1_k127_6670174_75 - - - - 0.000000000002723 79.0
HKD1_k127_6670174_76 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000001627 66.0
HKD1_k127_6670174_77 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000002065 65.0
HKD1_k127_6670174_78 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000004954 70.0
HKD1_k127_6670174_79 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000001126 66.0
HKD1_k127_6670174_8 Belongs to the aconitase IPM isomerase family K01703 - 4.2.1.33,4.2.1.35 5.269e-216 694.0
HKD1_k127_6670174_81 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000002459 63.0
HKD1_k127_6670174_82 cytochrome complex assembly K02198,K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.0000233 56.0
HKD1_k127_6670174_83 Protein of unknown function DUF45 K07043 - - 0.0000737 55.0
HKD1_k127_6670174_84 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000369 53.0
HKD1_k127_6670174_9 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 597.0
HKD1_k127_6687381_0 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 475.0
HKD1_k127_6687381_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 466.0
HKD1_k127_6687381_10 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000001186 136.0
HKD1_k127_6687381_11 - - - - 0.0000000000000000000000018 117.0
HKD1_k127_6687381_12 - - - - 0.000000005422 69.0
HKD1_k127_6687381_2 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 396.0
HKD1_k127_6687381_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 404.0
HKD1_k127_6687381_4 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 283.0
HKD1_k127_6687381_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002028 266.0
HKD1_k127_6687381_6 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000003016 187.0
HKD1_k127_6687381_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000548 152.0
HKD1_k127_6687381_8 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000321 150.0
HKD1_k127_6687381_9 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000002812 142.0
HKD1_k127_6822334_0 dna ligase - - - 6.927e-215 675.0
HKD1_k127_6822334_1 Belongs to the aldehyde dehydrogenase family K00130,K00151 - 1.2.1.60,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 542.0
HKD1_k127_6822334_2 ATP dependent DNA ligase C terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 496.0
HKD1_k127_6822334_3 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 455.0
HKD1_k127_6822334_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 467.0
HKD1_k127_6822334_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14751 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 369.0
HKD1_k127_6822334_6 - - - - 0.000000000000000000000000000000000000000000000000107 192.0
HKD1_k127_685053_0 NAD(P)H quinone oxidoreductase, PIG3 family K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 319.0
HKD1_k127_685053_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001613 265.0
HKD1_k127_685053_10 Phytanoyl-CoA dioxygenase - - - 0.0000000000000000000000000004779 126.0
HKD1_k127_685053_11 Glyoxalase-like domain - - - 0.000000000000000009312 90.0
HKD1_k127_685053_13 Fis family transcriptional regulator - - - 0.0000000002521 74.0
HKD1_k127_685053_2 RmlD substrate binding domain K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000007843 221.0
HKD1_k127_685053_3 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000004284 207.0
HKD1_k127_685053_4 dCMP deaminase activity K01493 GO:0003674,GO:0003824,GO:0004132,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046078,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.12 0.0000000000000000000000000000000000000000000000000005849 196.0
HKD1_k127_685053_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000001654 181.0
HKD1_k127_685053_6 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000001576 150.0
HKD1_k127_685053_7 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000002805 148.0
HKD1_k127_685053_8 Putative aminopeptidase - - - 0.00000000000000000000000000000001013 147.0
HKD1_k127_685053_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000008094 144.0
HKD1_k127_7051257_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 1.009e-290 929.0
HKD1_k127_7051257_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 490.0
HKD1_k127_7051257_10 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000008586 165.0
HKD1_k127_7051257_11 acetyltransferase - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000739 179.0
HKD1_k127_7051257_12 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.00000000000000000000000000000000000001441 154.0
HKD1_k127_7051257_13 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000009152 152.0
HKD1_k127_7051257_14 Capsular polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000003985 136.0
HKD1_k127_7051257_15 LysM domain - - - 0.00000000000000000000000000000001484 148.0
HKD1_k127_7051257_16 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000001206 134.0
HKD1_k127_7051257_17 -O-antigen K02847 - - 0.000000000000001083 92.0
HKD1_k127_7051257_18 VanZ like family - - - 0.00006415 55.0
HKD1_k127_7051257_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 472.0
HKD1_k127_7051257_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 422.0
HKD1_k127_7051257_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 335.0
HKD1_k127_7051257_5 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 309.0
HKD1_k127_7051257_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000003527 260.0
HKD1_k127_7051257_7 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000009127 251.0
HKD1_k127_7051257_8 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000002662 196.0
HKD1_k127_7051257_9 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000002381 171.0
HKD1_k127_7054860_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 7.991e-226 759.0
HKD1_k127_7054860_1 Protein of unknown function (DUF2961) - - - 2.601e-196 616.0
HKD1_k127_7054860_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 354.0
HKD1_k127_7054860_11 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 355.0
HKD1_k127_7054860_12 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 345.0
HKD1_k127_7054860_13 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 326.0
HKD1_k127_7054860_14 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 321.0
HKD1_k127_7054860_15 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 289.0
HKD1_k127_7054860_16 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 265.0
HKD1_k127_7054860_17 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000003888 226.0
HKD1_k127_7054860_18 enoyl-CoA hydratase isomerase family protein - - - 0.0000000000000000000000000000000000000000000000000000009448 201.0
HKD1_k127_7054860_19 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000002164 162.0
HKD1_k127_7054860_2 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 621.0
HKD1_k127_7054860_20 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000002951 143.0
HKD1_k127_7054860_22 - - - - 0.0000000000000000000000000003379 131.0
HKD1_k127_7054860_23 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000004886 120.0
HKD1_k127_7054860_24 transcriptional regulator K10913 - - 0.000000000000000000000000005584 118.0
HKD1_k127_7054860_25 acetyltransferase - - - 0.0000000000003275 76.0
HKD1_k127_7054860_26 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000009852 82.0
HKD1_k127_7054860_27 transmembrane transporter activity - - - 0.000000000001102 75.0
HKD1_k127_7054860_28 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000002996 62.0
HKD1_k127_7054860_29 sequence-specific DNA binding K07726 - - 0.00000002272 64.0
HKD1_k127_7054860_3 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 588.0
HKD1_k127_7054860_4 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 531.0
HKD1_k127_7054860_5 dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 474.0
HKD1_k127_7054860_6 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 464.0
HKD1_k127_7054860_7 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 462.0
HKD1_k127_7054860_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 445.0
HKD1_k127_7054860_9 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 360.0
HKD1_k127_7093992_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 4.87e-292 906.0
HKD1_k127_7093992_1 FtsH Extracellular K03798 - - 4.474e-233 737.0
HKD1_k127_7093992_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000002092 248.0
HKD1_k127_7093992_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000002768 241.0
HKD1_k127_7093992_12 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000006411 255.0
HKD1_k127_7093992_13 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000000000000009267 204.0
HKD1_k127_7093992_14 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000006127 192.0
HKD1_k127_7093992_15 - - - - 0.0000000000000000000000000000000000000000005402 175.0
HKD1_k127_7093992_16 Collagen triple helix repeat (20 copies) - - - 0.00000000000000000000000000000000000000009378 169.0
HKD1_k127_7093992_17 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000003946 159.0
HKD1_k127_7093992_18 rRNA (guanine-N2-)-methyltransferase activity - - - 0.00000000000000000005745 99.0
HKD1_k127_7093992_19 tetR family - - - 0.00000000000000000006669 98.0
HKD1_k127_7093992_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 551.0
HKD1_k127_7093992_20 dehydratase - - - 0.00000000000000007211 92.0
HKD1_k127_7093992_21 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.0000000000003448 74.0
HKD1_k127_7093992_22 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.000000000004097 79.0
HKD1_k127_7093992_23 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000002558 75.0
HKD1_k127_7093992_24 Protein of unknown function (DUF3467) - - - 0.0000000005062 66.0
HKD1_k127_7093992_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 500.0
HKD1_k127_7093992_4 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 449.0
HKD1_k127_7093992_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 431.0
HKD1_k127_7093992_6 PFAM AMP-dependent synthetase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 362.0
HKD1_k127_7093992_7 Phytanoyl-CoA dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 319.0
HKD1_k127_7093992_8 N-terminal half of MaoC dehydratase K18290 - 4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000001397 265.0
HKD1_k127_7093992_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001123 277.0
HKD1_k127_7123749_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 573.0
HKD1_k127_7123749_1 Bacterial type II/III secretion system short domain K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 403.0
HKD1_k127_7123749_10 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000583 154.0
HKD1_k127_7123749_11 secretion system protein G K02456 - - 0.00000000000000000000000000000000427 147.0
HKD1_k127_7123749_12 DivIVA protein K04074 - - 0.0000000000000000000008901 109.0
HKD1_k127_7123749_13 Putative regulatory protein - - - 0.0000000000000381 76.0
HKD1_k127_7123749_14 PFAM General secretion pathway protein K K02460 - - 0.0000000001085 75.0
HKD1_k127_7123749_15 Type II transport protein GspH K02457 - - 0.0000004615 59.0
HKD1_k127_7123749_16 Type II secretion system (T2SS), protein J K02459 - - 0.000002892 60.0
HKD1_k127_7123749_17 Type IV pilus assembly protein PilM; K02662 - - 0.000006318 60.0
HKD1_k127_7123749_2 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 321.0
HKD1_k127_7123749_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
HKD1_k127_7123749_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 304.0
HKD1_k127_7123749_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000008646 231.0
HKD1_k127_7123749_6 metallo-beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000004057 220.0
HKD1_k127_7123749_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000004932 201.0
HKD1_k127_7123749_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000133 185.0
HKD1_k127_7123749_9 Maf-like protein K06287 - - 0.000000000000000000000000000000000000001352 169.0
HKD1_k127_7188460_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 584.0
HKD1_k127_7188460_1 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 404.0
HKD1_k127_7188460_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 397.0
HKD1_k127_7188460_3 water channel activity K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000001785 249.0
HKD1_k127_7188460_4 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000001915 167.0
HKD1_k127_7188460_5 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000002395 139.0
HKD1_k127_7188460_6 Acetyltransferase (GNAT) domain - - - 0.000000009947 58.0
HKD1_k127_7188706_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 509.0
HKD1_k127_7188706_1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 383.0
HKD1_k127_7188706_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 317.0
HKD1_k127_7188706_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004753 274.0
HKD1_k127_7188706_4 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001169 289.0
HKD1_k127_7188706_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001576 251.0
HKD1_k127_7188706_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000006734 183.0
HKD1_k127_7188706_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000009198 112.0
HKD1_k127_7188706_8 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000003061 117.0
HKD1_k127_7188706_9 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000004291 56.0
HKD1_k127_718903_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 394.0
HKD1_k127_718903_1 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002543 249.0
HKD1_k127_718903_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000009721 126.0
HKD1_k127_718903_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000006391 116.0
HKD1_k127_718903_12 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000004068 111.0
HKD1_k127_718903_13 DSBA-like thioredoxin domain - - - 0.00000000000000000000000006972 123.0
HKD1_k127_718903_14 Haem-degrading - - - 0.00000000000000000002377 100.0
HKD1_k127_718903_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.00000000000000000004102 106.0
HKD1_k127_718903_17 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000002632 78.0
HKD1_k127_718903_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000002837 207.0
HKD1_k127_718903_3 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000001095 193.0
HKD1_k127_718903_4 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000005496 187.0
HKD1_k127_718903_5 Putative cyclase - - - 0.00000000000000000000000000000000000000000008034 162.0
HKD1_k127_718903_6 Protein of unknown function (DUF1272) K09984 - - 0.00000000000000000000000000000000000000008594 168.0
HKD1_k127_718903_7 SPTR CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000000000000001255 126.0
HKD1_k127_718903_8 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000007978 134.0
HKD1_k127_718903_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000002886 118.0
HKD1_k127_7206361_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1389.0
HKD1_k127_7206361_1 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1051.0
HKD1_k127_7206361_10 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 392.0
HKD1_k127_7206361_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 366.0
HKD1_k127_7206361_12 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 344.0
HKD1_k127_7206361_13 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 318.0
HKD1_k127_7206361_14 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001903 296.0
HKD1_k127_7206361_15 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000000000000000000000000000000000000000001041 241.0
HKD1_k127_7206361_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.000000000000000000000000000000000000000000000000000000000000000009534 239.0
HKD1_k127_7206361_17 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001178 257.0
HKD1_k127_7206361_18 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000003089 224.0
HKD1_k127_7206361_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000008997 216.0
HKD1_k127_7206361_2 Glycosyl transferase family group 2 - - - 5.834e-286 902.0
HKD1_k127_7206361_20 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000005061 227.0
HKD1_k127_7206361_21 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000003008 209.0
HKD1_k127_7206361_22 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000005306 204.0
HKD1_k127_7206361_23 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000001689 184.0
HKD1_k127_7206361_24 penicillin-binding protein - - - 0.0000000000000000000000000000000000000000000000005759 194.0
HKD1_k127_7206361_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000001205 191.0
HKD1_k127_7206361_26 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000001828 192.0
HKD1_k127_7206361_27 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000004313 181.0
HKD1_k127_7206361_28 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000003541 178.0
HKD1_k127_7206361_29 diguanylate cyclase - - - 0.0000000000000000000000000000000000001183 162.0
HKD1_k127_7206361_3 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771 4.1.1.32 1.365e-272 884.0
HKD1_k127_7206361_30 Right handed beta helix region - - - 0.000000000000000000000000000000000654 151.0
HKD1_k127_7206361_31 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000001082 116.0
HKD1_k127_7206361_32 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000008431 116.0
HKD1_k127_7206361_33 Thioesterase K07107,K12073 - 3.1.2.28 0.000000000000000000000005039 109.0
HKD1_k127_7206361_34 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000001274 113.0
HKD1_k127_7206361_36 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000002846 81.0
HKD1_k127_7206361_37 Protein of unknown function (DUF1328) - - - 0.0000000001545 68.0
HKD1_k127_7206361_38 Amidohydrolase - - - 0.0000000003237 61.0
HKD1_k127_7206361_39 Pfam Bacterial regulatory proteins, tetR family - - - 0.000000000538 70.0
HKD1_k127_7206361_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 581.0
HKD1_k127_7206361_40 - - - - 0.00000003213 66.0
HKD1_k127_7206361_41 - - - - 0.0000004561 61.0
HKD1_k127_7206361_42 - - - - 0.0000881 54.0
HKD1_k127_7206361_43 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0004353 44.0
HKD1_k127_7206361_5 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 530.0
HKD1_k127_7206361_6 Sterol-sensing domain of SREBP cleavage-activation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 549.0
HKD1_k127_7206361_7 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 524.0
HKD1_k127_7206361_8 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 518.0
HKD1_k127_7206361_9 Cytochrome P450 K15981 - 1.14.13.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 415.0
HKD1_k127_7207725_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 632.0
HKD1_k127_7207725_10 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 259.0
HKD1_k127_7207725_11 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000002263 224.0
HKD1_k127_7207725_12 Nitroreductase family - - - 0.000000000000000000000000000000000000000000002703 174.0
HKD1_k127_7207725_13 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000002823 172.0
HKD1_k127_7207725_14 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000004232 159.0
HKD1_k127_7207725_15 - - - - 0.0000000000000000000000000000000000000004123 156.0
HKD1_k127_7207725_16 Protein of unknown function (DUF533) - - - 0.000000000000000000000000000000000005844 147.0
HKD1_k127_7207725_17 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000009951 137.0
HKD1_k127_7207725_18 Phosphate acyltransferases - - - 0.000000000000000000000000000002643 131.0
HKD1_k127_7207725_19 - - - - 0.000000000000000000000000005366 115.0
HKD1_k127_7207725_2 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 530.0
HKD1_k127_7207725_20 Putative serine esterase (DUF676) - - - 0.0000000000000000000000000324 117.0
HKD1_k127_7207725_21 Belongs to the ompA family K03286 - - 0.000000000000000001415 99.0
HKD1_k127_7207725_22 oxidoreductase activity - - - 0.000001979 49.0
HKD1_k127_7207725_23 Metallo-beta-lactamase superfamily - - - 0.000002317 55.0
HKD1_k127_7207725_24 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000002897 49.0
HKD1_k127_7207725_3 membrane protein, terc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 493.0
HKD1_k127_7207725_4 COG0625 Glutathione S-transferase K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 458.0
HKD1_k127_7207725_5 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 432.0
HKD1_k127_7207725_6 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 385.0
HKD1_k127_7207725_7 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 363.0
HKD1_k127_7207725_8 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 342.0
HKD1_k127_7207725_9 L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 304.0
HKD1_k127_7211254_0 Adenylate cyclase - - - 1.611e-276 864.0
HKD1_k127_7211254_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 4.428e-195 636.0
HKD1_k127_7211254_10 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 357.0
HKD1_k127_7211254_11 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 311.0
HKD1_k127_7211254_12 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000008051 261.0
HKD1_k127_7211254_13 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
HKD1_k127_7211254_14 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000834 218.0
HKD1_k127_7211254_15 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000003421 221.0
HKD1_k127_7211254_16 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000005688 183.0
HKD1_k127_7211254_17 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000000000001856 191.0
HKD1_k127_7211254_19 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000002648 175.0
HKD1_k127_7211254_2 DNA polymerase IV (family X) K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 577.0
HKD1_k127_7211254_20 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.00000000000000000000000000000000000000009083 162.0
HKD1_k127_7211254_21 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000004478 164.0
HKD1_k127_7211254_22 Pentapeptide repeat protein - - - 0.0000000000000000000000000000000000001782 147.0
HKD1_k127_7211254_23 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000001371 138.0
HKD1_k127_7211254_24 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000006123 132.0
HKD1_k127_7211254_25 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000004974 102.0
HKD1_k127_7211254_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000004439 86.0
HKD1_k127_7211254_27 amino acid transport - - - 0.000000000000002019 91.0
HKD1_k127_7211254_28 Thiamine-binding protein - - - 0.0000000000628 68.0
HKD1_k127_7211254_3 Cystathionine gamma-synthase K01739 GO:0000096,GO:0000097,GO:0001887,GO:0003674,GO:0003824,GO:0003962,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 524.0
HKD1_k127_7211254_30 - - - - 0.00001217 53.0
HKD1_k127_7211254_32 Transcriptional regulator - - - 0.0002962 49.0
HKD1_k127_7211254_4 amidohydrolase K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 514.0
HKD1_k127_7211254_5 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 478.0
HKD1_k127_7211254_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 424.0
HKD1_k127_7211254_7 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 416.0
HKD1_k127_7211254_8 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 392.0
HKD1_k127_7211254_9 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
HKD1_k127_723345_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1459.0
HKD1_k127_723345_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1216.0
HKD1_k127_723345_10 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 354.0
HKD1_k127_723345_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 325.0
HKD1_k127_723345_12 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 318.0
HKD1_k127_723345_13 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 307.0
HKD1_k127_723345_14 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 312.0
HKD1_k127_723345_15 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001527 274.0
HKD1_k127_723345_16 FAD dependent oxidoreductase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000001933 228.0
HKD1_k127_723345_17 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000001641 219.0
HKD1_k127_723345_18 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000007485 214.0
HKD1_k127_723345_19 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000205 201.0
HKD1_k127_723345_2 DNA polymerase type-B family K02336 - 2.7.7.7 5.458e-206 665.0
HKD1_k127_723345_20 Protein tyrosine kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000000003504 207.0
HKD1_k127_723345_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000005171 194.0
HKD1_k127_723345_22 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000001497 185.0
HKD1_k127_723345_23 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000005098 196.0
HKD1_k127_723345_24 PFAM Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000008624 181.0
HKD1_k127_723345_25 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000005897 184.0
HKD1_k127_723345_26 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000006041 182.0
HKD1_k127_723345_27 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000001083 189.0
HKD1_k127_723345_28 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000002421 179.0
HKD1_k127_723345_29 Cation efflux family - - - 0.0000000000000000000000000000000000000000009865 181.0
HKD1_k127_723345_3 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 511.0
HKD1_k127_723345_30 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000003736 154.0
HKD1_k127_723345_31 Alginate export - - - 0.0000000000000000000000000000000000000003777 166.0
HKD1_k127_723345_32 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0000000000000000000000000000000000007329 147.0
HKD1_k127_723345_33 Methyltransferase domain - - - 0.000000000000000000000000000000000001259 155.0
HKD1_k127_723345_34 PFAM alpha beta hydrolase - - - 0.00000000000000000000000000000002998 137.0
HKD1_k127_723345_35 Alpha beta hydrolase K22318 - - 0.000000000000000000000000008615 119.0
HKD1_k127_723345_36 FHA domain - - - 0.0000000000000000000007288 106.0
HKD1_k127_723345_37 - - - - 0.000000007917 63.0
HKD1_k127_723345_38 TPM domain K06872 - - 0.000005112 59.0
HKD1_k127_723345_39 YCII-related domain - - - 0.00008495 50.0
HKD1_k127_723345_4 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 515.0
HKD1_k127_723345_40 Fibronectin type III domain - - - 0.0001759 53.0
HKD1_k127_723345_5 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 468.0
HKD1_k127_723345_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 459.0
HKD1_k127_723345_7 Bifunctional purine biosynthesis protein PURH. Source PGD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 453.0
HKD1_k127_723345_8 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 428.0
HKD1_k127_723345_9 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 390.0
HKD1_k127_7275198_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.18e-212 676.0
HKD1_k127_7275198_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.322e-206 659.0
HKD1_k127_7275198_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 367.0
HKD1_k127_7275198_11 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 343.0
HKD1_k127_7275198_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 340.0
HKD1_k127_7275198_13 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 324.0
HKD1_k127_7275198_14 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000217 291.0
HKD1_k127_7275198_15 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000006842 277.0
HKD1_k127_7275198_16 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002127 270.0
HKD1_k127_7275198_17 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001012 268.0
HKD1_k127_7275198_18 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000000000000000000000000000000001504 257.0
HKD1_k127_7275198_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000005528 243.0
HKD1_k127_7275198_2 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 548.0
HKD1_k127_7275198_20 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000001571 237.0
HKD1_k127_7275198_21 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001621 226.0
HKD1_k127_7275198_22 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000006522 207.0
HKD1_k127_7275198_23 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000006435 204.0
HKD1_k127_7275198_24 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000005944 193.0
HKD1_k127_7275198_25 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000007646 196.0
HKD1_k127_7275198_26 protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000007007 182.0
HKD1_k127_7275198_27 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000001588 179.0
HKD1_k127_7275198_28 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000004053 175.0
HKD1_k127_7275198_29 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000008126 177.0
HKD1_k127_7275198_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 530.0
HKD1_k127_7275198_30 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000002205 174.0
HKD1_k127_7275198_31 PFAM Protein phosphatase 2C K20074 - 3.1.3.16 0.00000000000000000000000000000000000000001333 169.0
HKD1_k127_7275198_32 NUDIX domain - - - 0.000000000000000000000000000000000000001768 152.0
HKD1_k127_7275198_33 GNAT acetyltransferase - - - 0.000000000000000000000000000000000000004288 159.0
HKD1_k127_7275198_34 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000002532 163.0
HKD1_k127_7275198_35 Histidine kinase - - - 0.0000000000000000000000000000000002235 149.0
HKD1_k127_7275198_36 COG3420 Nitrous oxidase accessory protein - - - 0.0000000000000000000000000000005271 141.0
HKD1_k127_7275198_37 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000002623 133.0
HKD1_k127_7275198_38 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000000008435 115.0
HKD1_k127_7275198_39 Dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000001284 104.0
HKD1_k127_7275198_4 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 493.0
HKD1_k127_7275198_40 Phosphoribosyl transferase domain K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.00000000000000000129 93.0
HKD1_k127_7275198_41 Peptidase MA superfamily - - - 0.00000000000000000241 96.0
HKD1_k127_7275198_42 - - - - 0.00000000000000008766 85.0
HKD1_k127_7275198_43 Phospholipase D Active site motif - - - 0.000000000000000156 88.0
HKD1_k127_7275198_44 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000002113 77.0
HKD1_k127_7275198_45 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000006738 67.0
HKD1_k127_7275198_46 Catalyzes the synthesis of activated sulfate - - - 0.0000003145 58.0
HKD1_k127_7275198_47 Saccharopine dehydrogenase NADP binding domain - - - 0.000001164 61.0
HKD1_k127_7275198_48 - - - - 0.000007511 51.0
HKD1_k127_7275198_49 Hemerythrin HHE cation binding domain protein K09155 - - 0.00007818 50.0
HKD1_k127_7275198_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 446.0
HKD1_k127_7275198_50 - - - - 0.0001658 50.0
HKD1_k127_7275198_51 Lysylphosphatidylglycerol synthase TM region - - - 0.0002235 54.0
HKD1_k127_7275198_6 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 438.0
HKD1_k127_7275198_7 heme binding K00463 - 1.13.11.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 433.0
HKD1_k127_7275198_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 367.0
HKD1_k127_7275198_9 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 347.0
HKD1_k127_736298_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1050.0
HKD1_k127_736298_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 567.0
HKD1_k127_736298_10 Domain of unknown function (DUF1998) K06877 - - 0.000000000000004405 83.0
HKD1_k127_736298_2 COG1233 Phytoene dehydrogenase and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 588.0
HKD1_k127_736298_3 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 542.0
HKD1_k127_736298_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 421.0
HKD1_k127_736298_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 390.0
HKD1_k127_736298_6 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000005412 156.0
HKD1_k127_736298_7 Protein of unknown function (DUF2834) - - - 0.0000000000000000000000000000000000001917 149.0
HKD1_k127_736298_8 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000007067 135.0
HKD1_k127_736298_9 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000001656 110.0
HKD1_k127_7472510_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 422.0
HKD1_k127_7472510_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 383.0
HKD1_k127_7472510_10 N-terminal domain of galactosyltransferase - - - 0.0000000000000000000000000000004352 133.0
HKD1_k127_7472510_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000007517 114.0
HKD1_k127_7472510_12 Acyl-ACP thioesterase K07107 - - 0.0000000000000000001497 102.0
HKD1_k127_7472510_13 Methyltransferase FkbM domain - - - 0.000000000000004801 84.0
HKD1_k127_7472510_14 Mycolic acid cyclopropane synthetase - - - 0.00000000000003335 87.0
HKD1_k127_7472510_15 Polysaccharide biosynthesis protein - - - 0.000000000003894 79.0
HKD1_k127_7472510_16 ATP hydrolysis coupled proton transport - - - 0.0001444 54.0
HKD1_k127_7472510_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 392.0
HKD1_k127_7472510_3 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 349.0
HKD1_k127_7472510_4 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 304.0
HKD1_k127_7472510_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
HKD1_k127_7472510_6 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000004798 235.0
HKD1_k127_7472510_7 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001695 245.0
HKD1_k127_7472510_9 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000003625 148.0
HKD1_k127_7480339_0 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 385.0
HKD1_k127_7480339_1 cytochrome p450 K21117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 261.0
HKD1_k127_7480339_2 YHS domain protein - - - 0.00000000000000000000000000000000000000000000000000000762 192.0
HKD1_k127_7480339_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000006245 168.0
HKD1_k127_7480339_4 - - - - 0.0000000000000000000000000000000000001629 153.0
HKD1_k127_7480339_5 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000003354 163.0
HKD1_k127_7480339_6 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000001085 152.0
HKD1_k127_7480339_7 YHS domain protein - - - 0.000000000000000000000000000001429 141.0
HKD1_k127_7480339_8 YHS domain protein - - - 0.0000000000000000000000000002713 134.0
HKD1_k127_7495248_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.206e-239 749.0
HKD1_k127_7495248_1 Voltage gated chloride channel - - - 1.089e-214 682.0
HKD1_k127_7495248_10 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 355.0
HKD1_k127_7495248_11 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 334.0
HKD1_k127_7495248_12 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 301.0
HKD1_k127_7495248_13 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000005792 230.0
HKD1_k127_7495248_14 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000001406 233.0
HKD1_k127_7495248_15 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000004607 209.0
HKD1_k127_7495248_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000118 195.0
HKD1_k127_7495248_17 cellular response to dsDNA K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000005902 173.0
HKD1_k127_7495248_18 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000004183 169.0
HKD1_k127_7495248_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 566.0
HKD1_k127_7495248_20 Permease of the major facilitator superfamily K08369 - - 0.000000000000000000000000000000000001015 156.0
HKD1_k127_7495248_21 Thioesterase superfamily - - - 0.000000000000000000000000000000000001553 145.0
HKD1_k127_7495248_22 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000006464 144.0
HKD1_k127_7495248_23 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000001785 152.0
HKD1_k127_7495248_24 CcmB protein K02194 - - 0.000000000000000000000004374 117.0
HKD1_k127_7495248_25 - - - - 0.000000000000000000001628 106.0
HKD1_k127_7495248_26 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000001237 91.0
HKD1_k127_7495248_27 Biotin-lipoyl like - - - 0.0000000000000000003021 89.0
HKD1_k127_7495248_28 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000002788 89.0
HKD1_k127_7495248_3 PFAM Cytochrome c assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 567.0
HKD1_k127_7495248_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000006855 69.0
HKD1_k127_7495248_31 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000007148 68.0
HKD1_k127_7495248_32 Cytochrome c - - - 0.000000006246 70.0
HKD1_k127_7495248_33 TRL-like protein family - - - 0.0000002606 56.0
HKD1_k127_7495248_34 - - - - 0.00007601 50.0
HKD1_k127_7495248_35 - - - - 0.0003636 53.0
HKD1_k127_7495248_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 486.0
HKD1_k127_7495248_5 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 473.0
HKD1_k127_7495248_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 463.0
HKD1_k127_7495248_7 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 376.0
HKD1_k127_7495248_8 PFAM cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 357.0
HKD1_k127_7495248_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 342.0
HKD1_k127_7638492_0 AMP-binding enzyme K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 557.0
HKD1_k127_7638492_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 373.0
HKD1_k127_7638492_10 Rhomboid family - - - 0.00000000000000000000000000000000005327 154.0
HKD1_k127_7638492_11 Cytochrome c554 and c-prime - - - 0.000000000000000000000000001253 118.0
HKD1_k127_7638492_12 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.000000000000000000000003274 105.0
HKD1_k127_7638492_13 Protein of unknown function (DUF455) - - - 0.00000000002716 77.0
HKD1_k127_7638492_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 351.0
HKD1_k127_7638492_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 337.0
HKD1_k127_7638492_4 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000007224 244.0
HKD1_k127_7638492_5 KR domain - GO:0003674,GO:0003824,GO:0004799,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008168,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016740,GO:0016741,GO:0019889,GO:0032259,GO:0033554,GO:0034599,GO:0042083,GO:0042221,GO:0042558,GO:0044237,GO:0046483,GO:0047040,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000002535 227.0
HKD1_k127_7638492_6 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000003095 198.0
HKD1_k127_7638492_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000003207 192.0
HKD1_k127_7638492_9 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000001282 170.0
HKD1_k127_7644642_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 542.0
HKD1_k127_7644642_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 372.0
HKD1_k127_7644642_10 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000003112 182.0
HKD1_k127_7644642_11 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.0000000000000000000000000004328 119.0
HKD1_k127_7644642_12 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000006052 121.0
HKD1_k127_7644642_13 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001161 84.0
HKD1_k127_7644642_14 Antibiotic biosynthesis monooxygenase - - - 0.000000000003173 72.0
HKD1_k127_7644642_15 Periplasmic binding protein K02016 - - 0.0000000004471 73.0
HKD1_k127_7644642_16 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0000002687 63.0
HKD1_k127_7644642_17 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000008647 61.0
HKD1_k127_7644642_18 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000002422 61.0
HKD1_k127_7644642_2 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 377.0
HKD1_k127_7644642_3 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006619 292.0
HKD1_k127_7644642_4 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008466 280.0
HKD1_k127_7644642_5 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000001628 262.0
HKD1_k127_7644642_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000002264 228.0
HKD1_k127_7644642_7 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000005415 203.0
HKD1_k127_7644642_8 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000007869 186.0
HKD1_k127_7644642_9 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000000000000000000000000000000000000000000716 183.0
HKD1_k127_7668521_0 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 581.0
HKD1_k127_7668521_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 427.0
HKD1_k127_7668521_10 cytochrome c5 - - - 0.0000000000000000000004974 100.0
HKD1_k127_7668521_11 transcriptional regulator - - - 0.000000000006648 78.0
HKD1_k127_7668521_12 - - - - 0.00000007102 63.0
HKD1_k127_7668521_2 Lumazine binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 310.0
HKD1_k127_7668521_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000000000002457 218.0
HKD1_k127_7668521_4 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000008354 215.0
HKD1_k127_7668521_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000005313 207.0
HKD1_k127_7668521_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000005858 172.0
HKD1_k127_7668521_7 Phytanoyl-CoA dioxygenase (PhyH) K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.000000000000000000000000000000000000006035 155.0
HKD1_k127_7668521_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000001445 130.0
HKD1_k127_7668521_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000001558 121.0
HKD1_k127_7714861_0 long-chain fatty acid transport protein - - - 0.0 1244.0
HKD1_k127_7714861_1 PFAM Peptidase family M3 K01414 - 3.4.24.70 7.07e-279 891.0
HKD1_k127_7714861_10 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 301.0
HKD1_k127_7714861_11 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 GO:0000003,GO:0000049,GO:0000166,GO:0000959,GO:0000963,GO:0000964,GO:0000965,GO:0000966,GO:0001510,GO:0001540,GO:0002165,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003857,GO:0004303,GO:0005102,GO:0005488,GO:0005496,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005783,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007548,GO:0007568,GO:0007569,GO:0008033,GO:0008134,GO:0008150,GO:0008152,GO:0008202,GO:0008205,GO:0008209,GO:0008210,GO:0008289,GO:0008406,GO:0008584,GO:0008709,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009117,GO:0009150,GO:0009259,GO:0009295,GO:0009451,GO:0009791,GO:0009987,GO:0010467,GO:0010817,GO:0012505,GO:0016020,GO:0016043,GO:0016054,GO:0016070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0018454,GO:0019637,GO:0019693,GO:0019752,GO:0022414,GO:0022607,GO:0030154,GO:0030283,GO:0030331,GO:0030488,GO:0030677,GO:0030678,GO:0031123,GO:0031974,GO:0032259,GO:0032501,GO:0032502,GO:0032787,GO:0032991,GO:0033218,GO:0033327,GO:0033764,GO:0033865,GO:0033875,GO:0034032,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0034754,GO:0035257,GO:0035258,GO:0035383,GO:0036094,GO:0042180,GO:0042277,GO:0042445,GO:0042645,GO:0042780,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044260,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045137,GO:0045455,GO:0046395,GO:0046483,GO:0046546,GO:0046661,GO:0047022,GO:0047035,GO:0048037,GO:0048513,GO:0048608,GO:0048731,GO:0048856,GO:0048869,GO:0050662,GO:0051186,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0051427,GO:0055086,GO:0055114,GO:0061458,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070525,GO:0070900,GO:0070901,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0090304,GO:0090646,GO:0097159,GO:0097745,GO:0098798,GO:0099116,GO:0140053,GO:1900864,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901615,GO:1902494,GO:1902555,GO:1902652,GO:1905348,GO:1990180,GO:1990904 1.1.1.178,1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001986 308.0
HKD1_k127_7714861_12 'glutamate synthase K00123,K00317,K00528,K09835 - 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
HKD1_k127_7714861_13 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009892 305.0
HKD1_k127_7714861_14 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002754 262.0
HKD1_k127_7714861_15 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009851 267.0
HKD1_k127_7714861_16 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000002498 228.0
HKD1_k127_7714861_17 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000001767 237.0
HKD1_k127_7714861_18 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000002417 233.0
HKD1_k127_7714861_19 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.000000000000000000000000000000000000000000000000000000000191 215.0
HKD1_k127_7714861_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 6.796e-233 736.0
HKD1_k127_7714861_20 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000004048 183.0
HKD1_k127_7714861_21 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000009615 155.0
HKD1_k127_7714861_22 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000001177 141.0
HKD1_k127_7714861_23 Sulfotransferase family - - - 0.0000000000000000000000000000000001339 147.0
HKD1_k127_7714861_24 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000002741 134.0
HKD1_k127_7714861_25 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000001895 111.0
HKD1_k127_7714861_26 haloacid dehalogenase-like hydrolase K01560,K07025 - 3.8.1.2 0.00000000000000000001533 106.0
HKD1_k127_7714861_27 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.0000000000000000001713 103.0
HKD1_k127_7714861_28 tetR family - - - 0.000000000000002869 84.0
HKD1_k127_7714861_29 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000007523 88.0
HKD1_k127_7714861_3 General secretory system II, protein E domain protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 575.0
HKD1_k127_7714861_30 - - - - 0.0000000001975 68.0
HKD1_k127_7714861_31 ubiquitin - - - 0.00000008033 64.0
HKD1_k127_7714861_32 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000003208 58.0
HKD1_k127_7714861_33 glutaredoxin-like protein, YruB-family - - - 0.00001464 57.0
HKD1_k127_7714861_34 FR47-like protein - - - 0.0004589 54.0
HKD1_k127_7714861_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 565.0
HKD1_k127_7714861_5 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 560.0
HKD1_k127_7714861_6 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 402.0
HKD1_k127_7714861_7 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 356.0
HKD1_k127_7714861_8 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 333.0
HKD1_k127_7714861_9 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 325.0
HKD1_k127_7733403_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 601.0
HKD1_k127_7733403_1 conserved protein (COG2071) K09166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 284.0
HKD1_k127_7733403_10 Acetyltransferase (GNAT) family - - - 0.0000000000000000003329 101.0
HKD1_k127_7733403_11 Heavy metal translocating P-type atpase - - - 0.000000000000001556 93.0
HKD1_k127_7733403_12 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000003263 79.0
HKD1_k127_7733403_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000004666 56.0
HKD1_k127_7733403_14 Enoyl-(Acyl carrier protein) reductase - - - 0.000005019 51.0
HKD1_k127_7733403_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001369 213.0
HKD1_k127_7733403_3 - - - - 0.00000000000000000000000000000000000000000000001731 184.0
HKD1_k127_7733403_4 NUDIX domain - - - 0.000000000000000000000000000000000000000000003291 167.0
HKD1_k127_7733403_5 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000001058 165.0
HKD1_k127_7733403_6 phosphoglycerate mutase K01834 - 5.4.2.11 0.000000000000000000000000000000000000001392 154.0
HKD1_k127_7733403_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000002109 152.0
HKD1_k127_7733403_8 acetyltransferase - - - 0.00000000000000000000000008126 124.0
HKD1_k127_7733403_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000004052 108.0
HKD1_k127_7762026_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.068e-213 685.0
HKD1_k127_7762026_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.508e-209 679.0
HKD1_k127_7762026_10 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 436.0
HKD1_k127_7762026_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 408.0
HKD1_k127_7762026_12 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 399.0
HKD1_k127_7762026_13 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 377.0
HKD1_k127_7762026_14 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 371.0
HKD1_k127_7762026_15 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 330.0
HKD1_k127_7762026_16 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002436 306.0
HKD1_k127_7762026_17 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000237 281.0
HKD1_k127_7762026_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000727 254.0
HKD1_k127_7762026_19 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000008017 275.0
HKD1_k127_7762026_2 PFAM AMP-dependent synthetase and ligase K00666 - - 1.529e-207 658.0
HKD1_k127_7762026_20 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001396 270.0
HKD1_k127_7762026_21 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000005156 260.0
HKD1_k127_7762026_22 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000002093 252.0
HKD1_k127_7762026_23 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000003567 232.0
HKD1_k127_7762026_24 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000001258 224.0
HKD1_k127_7762026_25 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000002428 246.0
HKD1_k127_7762026_26 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
HKD1_k127_7762026_27 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000675 224.0
HKD1_k127_7762026_28 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000003785 228.0
HKD1_k127_7762026_29 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000001898 190.0
HKD1_k127_7762026_3 K+ potassium transporter K03549 - - 2.216e-200 644.0
HKD1_k127_7762026_30 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000008521 179.0
HKD1_k127_7762026_31 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000002167 188.0
HKD1_k127_7762026_32 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000002485 173.0
HKD1_k127_7762026_33 methyltransferase K21459 - 2.1.1.301 0.00000000000000000000000000000000000000000002561 172.0
HKD1_k127_7762026_34 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000003091 174.0
HKD1_k127_7762026_35 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000396 180.0
HKD1_k127_7762026_36 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000005807 168.0
HKD1_k127_7762026_37 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000307 180.0
HKD1_k127_7762026_38 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000006178 163.0
HKD1_k127_7762026_39 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000007347 174.0
HKD1_k127_7762026_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 566.0
HKD1_k127_7762026_40 Thioesterase - - - 0.000000000000000000000000000000000000000005112 168.0
HKD1_k127_7762026_41 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000007674 161.0
HKD1_k127_7762026_42 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000008875 167.0
HKD1_k127_7762026_43 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000001192 160.0
HKD1_k127_7762026_44 - - - - 0.00000000000000000000000000000001725 138.0
HKD1_k127_7762026_45 response regulator K15012 - - 0.0000000000000000000000000000004947 139.0
HKD1_k127_7762026_46 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 - 0.00000000000000000000000000001036 134.0
HKD1_k127_7762026_47 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000000003697 120.0
HKD1_k127_7762026_48 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000001505 129.0
HKD1_k127_7762026_49 repeat protein - - - 0.000000000000000000000004518 117.0
HKD1_k127_7762026_5 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 505.0
HKD1_k127_7762026_50 Cysteine-rich secretory protein family - - - 0.0000000000000000002924 98.0
HKD1_k127_7762026_51 Thioredoxin-like K06196 - - 0.000000000000000006992 91.0
HKD1_k127_7762026_52 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000001803 96.0
HKD1_k127_7762026_53 protein conserved in bacteria - - - 0.000000000000003535 83.0
HKD1_k127_7762026_54 - - - - 0.00000000002317 69.0
HKD1_k127_7762026_55 Putative adhesin - - - 0.000000006296 68.0
HKD1_k127_7762026_56 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000006324 66.0
HKD1_k127_7762026_57 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0001915 51.0
HKD1_k127_7762026_58 PFAM PEGA domain - - - 0.0009801 50.0
HKD1_k127_7762026_6 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 487.0
HKD1_k127_7762026_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 520.0
HKD1_k127_7762026_8 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 515.0
HKD1_k127_7762026_9 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 443.0
HKD1_k127_7765619_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000001517 164.0
HKD1_k127_7765619_1 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000002806 102.0
HKD1_k127_7765619_2 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000001733 97.0
HKD1_k127_7805286_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1244.0
HKD1_k127_7805286_1 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 1.435e-224 739.0
HKD1_k127_7805286_10 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 419.0
HKD1_k127_7805286_11 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 402.0
HKD1_k127_7805286_12 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 398.0
HKD1_k127_7805286_13 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 387.0
HKD1_k127_7805286_14 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 391.0
HKD1_k127_7805286_15 COG2124 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 387.0
HKD1_k127_7805286_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 372.0
HKD1_k127_7805286_17 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 357.0
HKD1_k127_7805286_18 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 372.0
HKD1_k127_7805286_19 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 367.0
HKD1_k127_7805286_2 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 618.0
HKD1_k127_7805286_20 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 346.0
HKD1_k127_7805286_21 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 344.0
HKD1_k127_7805286_22 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 341.0
HKD1_k127_7805286_23 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 334.0
HKD1_k127_7805286_24 efflux transmembrane transporter activity K18903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 349.0
HKD1_k127_7805286_25 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 308.0
HKD1_k127_7805286_26 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 320.0
HKD1_k127_7805286_27 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 328.0
HKD1_k127_7805286_28 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001618 298.0
HKD1_k127_7805286_29 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001856 280.0
HKD1_k127_7805286_3 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 576.0
HKD1_k127_7805286_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002839 278.0
HKD1_k127_7805286_31 Thiolase, C-terminal domain K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002353 298.0
HKD1_k127_7805286_32 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004123 269.0
HKD1_k127_7805286_33 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006126 266.0
HKD1_k127_7805286_34 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001114 267.0
HKD1_k127_7805286_35 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003791 260.0
HKD1_k127_7805286_36 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004401 272.0
HKD1_k127_7805286_37 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007012 265.0
HKD1_k127_7805286_38 PhoQ Sensor K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000005648 246.0
HKD1_k127_7805286_39 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005751 254.0
HKD1_k127_7805286_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 524.0
HKD1_k127_7805286_40 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000002524 244.0
HKD1_k127_7805286_42 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
HKD1_k127_7805286_43 Cytochrome P450 K00493 - 1.14.14.1 0.000000000000000000000000000000000000000000000000000000000001233 228.0
HKD1_k127_7805286_44 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000007128 219.0
HKD1_k127_7805286_45 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
HKD1_k127_7805286_46 TPR repeat - - - 0.000000000000000000000000000000000000000000000000003362 193.0
HKD1_k127_7805286_47 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000004229 189.0
HKD1_k127_7805286_48 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000002934 187.0
HKD1_k127_7805286_49 acetyltransferase - - - 0.00000000000000000000000000000000000000000000002183 178.0
HKD1_k127_7805286_5 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 502.0
HKD1_k127_7805286_50 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000002341 188.0
HKD1_k127_7805286_51 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000002125 177.0
HKD1_k127_7805286_52 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000000000000000000000000000004153 180.0
HKD1_k127_7805286_53 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000001001 168.0
HKD1_k127_7805286_55 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000002984 149.0
HKD1_k127_7805286_56 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000001452 156.0
HKD1_k127_7805286_57 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000003513 131.0
HKD1_k127_7805286_58 3D domain protein - - - 0.000000000000000000000000000002433 124.0
HKD1_k127_7805286_59 - - - - 0.000000000000000000000000000003024 139.0
HKD1_k127_7805286_6 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 512.0
HKD1_k127_7805286_60 transport system, permease component K01992 - - 0.000000000000000000000000000004756 138.0
HKD1_k127_7805286_61 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000002475 120.0
HKD1_k127_7805286_62 Belongs to the ompA family K03286 - - 0.00000000000000000000002273 106.0
HKD1_k127_7805286_63 - - - - 0.00000000000000000001704 96.0
HKD1_k127_7805286_64 - - - - 0.0000000000000000002938 104.0
HKD1_k127_7805286_65 protein homooligomerization - - - 0.00000000000000002647 93.0
HKD1_k127_7805286_66 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000009341 94.0
HKD1_k127_7805286_67 Major facilitator superfamily - - - 0.00000000001711 73.0
HKD1_k127_7805286_68 - - - - 0.00000000001886 76.0
HKD1_k127_7805286_69 NUDIX domain - - - 0.00000004986 66.0
HKD1_k127_7805286_7 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 458.0
HKD1_k127_7805286_8 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 436.0
HKD1_k127_7805286_9 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 419.0
HKD1_k127_7843190_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000001181 216.0
HKD1_k127_7843190_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000002256 190.0
HKD1_k127_7843190_2 PFAM WD domain, G-beta repeat - - - 0.000000000000000231 91.0
HKD1_k127_7843190_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000002056 60.0
HKD1_k127_7843190_4 cobalamin (vitamin B12) biosynthesis CbiX protein - - - 0.000008454 53.0
HKD1_k127_7843190_5 Protein of unknown function (DUF4079) - - - 0.00004061 51.0
HKD1_k127_7843190_6 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0002596 53.0
HKD1_k127_7881480_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.02e-262 837.0
HKD1_k127_7881480_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 601.0
HKD1_k127_7881480_10 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 322.0
HKD1_k127_7881480_11 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001601 279.0
HKD1_k127_7881480_12 Cytochrome c K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000003822 258.0
HKD1_k127_7881480_13 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000003136 214.0
HKD1_k127_7881480_14 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000001343 194.0
HKD1_k127_7881480_15 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000009433 186.0
HKD1_k127_7881480_16 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000001247 190.0
HKD1_k127_7881480_17 WHG domain - - - 0.000000000000000000000000000000000000001911 164.0
HKD1_k127_7881480_18 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000008151 145.0
HKD1_k127_7881480_19 MaoC like domain - - - 0.0000000000000000000000000000000001123 151.0
HKD1_k127_7881480_2 PFAM Di-heme cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 539.0
HKD1_k127_7881480_20 Sucrase/ferredoxin-like - - - 0.00000000000000000000003536 111.0
HKD1_k127_7881480_21 Protein of unknown function (DUF423) - - - 0.00000000000000000000909 108.0
HKD1_k127_7881480_22 RDD family - - - 0.00000000000000000009479 99.0
HKD1_k127_7881480_23 hydrolase (HAD superfamily) K07025 - - 0.000000000000000002049 101.0
HKD1_k127_7881480_24 Nitroreductase family - - - 0.00000000000000002659 88.0
HKD1_k127_7881480_25 Cupin 2, conserved barrel domain protein K21700 - - 0.00000000000000004227 84.0
HKD1_k127_7881480_26 Psort location CytoplasmicMembrane, score - - - 0.0000000000000005074 92.0
HKD1_k127_7881480_27 Nitroreductase family - - - 0.000000000001144 80.0
HKD1_k127_7881480_28 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000002054 70.0
HKD1_k127_7881480_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 576.0
HKD1_k127_7881480_4 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 504.0
HKD1_k127_7881480_5 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 462.0
HKD1_k127_7881480_6 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 431.0
HKD1_k127_7881480_7 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 428.0
HKD1_k127_7881480_8 dioxygenase K11159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 439.0
HKD1_k127_7881480_9 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 404.0
HKD1_k127_7971552_0 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 7.266e-243 756.0
HKD1_k127_7971552_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 551.0
HKD1_k127_7971552_2 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 382.0
HKD1_k127_7971552_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002638 299.0
HKD1_k127_7971552_5 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000008506 77.0
HKD1_k127_7977602_0 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 5.693e-227 720.0
HKD1_k127_7977602_1 fatty acid alpha-oxidation K12261 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 619.0
HKD1_k127_7977602_10 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003061 282.0
HKD1_k127_7977602_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004717 281.0
HKD1_k127_7977602_12 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001557 262.0
HKD1_k127_7977602_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004885 243.0
HKD1_k127_7977602_14 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000002886 233.0
HKD1_k127_7977602_15 Protein conserved in bacteria K09983 - - 0.0000000000000000000000000000000000000000000000000000000000000003004 238.0
HKD1_k127_7977602_16 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000001862 151.0
HKD1_k127_7977602_17 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000002115 145.0
HKD1_k127_7977602_18 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000003247 134.0
HKD1_k127_7977602_2 Domain of unknown function (DUF3463) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 561.0
HKD1_k127_7977602_20 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000004512 114.0
HKD1_k127_7977602_21 - - - - 0.0000000000000000000003168 111.0
HKD1_k127_7977602_22 Uncharacterized protein family UPF0016 - - - 0.0000000000000000001488 101.0
HKD1_k127_7977602_23 - - - - 0.000000000000000001284 98.0
HKD1_k127_7977602_24 - - - - 0.00000000000000002029 93.0
HKD1_k127_7977602_25 Peptidase family M28 - - - 0.000000000005922 72.0
HKD1_k127_7977602_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 482.0
HKD1_k127_7977602_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 432.0
HKD1_k127_7977602_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 386.0
HKD1_k127_7977602_6 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 347.0
HKD1_k127_7977602_7 SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 321.0
HKD1_k127_7977602_8 PFAM Prenyltransferase and squalene oxidase repeat K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 293.0
HKD1_k127_7977602_9 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001389 295.0
HKD1_k127_829263_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1020.0
HKD1_k127_829263_1 UPF0313 protein - - - 4.681e-279 871.0
HKD1_k127_829263_10 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000107 216.0
HKD1_k127_829263_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.0000000000000000000000000000000000000000001489 177.0
HKD1_k127_829263_12 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000002727 163.0
HKD1_k127_829263_13 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000001506 147.0
HKD1_k127_829263_14 SdpI/YhfL protein family - - - 0.0000003519 58.0
HKD1_k127_829263_2 related to 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 479.0
HKD1_k127_829263_3 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 499.0
HKD1_k127_829263_4 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 433.0
HKD1_k127_829263_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 375.0
HKD1_k127_829263_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 338.0
HKD1_k127_829263_7 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006987 298.0
HKD1_k127_829263_8 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002439 267.0
HKD1_k127_829263_9 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000001908 248.0
HKD1_k127_890297_0 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 491.0
HKD1_k127_890297_1 PD-(D/E)XK nuclease superfamily K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000003667 256.0
HKD1_k127_890297_10 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000002833 90.0
HKD1_k127_890297_12 PFAM helix-turn-helix domain protein - - - 0.00000000001114 69.0
HKD1_k127_890297_13 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K00372 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000004537 62.0
HKD1_k127_890297_14 bacterioferritin K02192 - - 0.00001716 49.0
HKD1_k127_890297_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000001358 236.0
HKD1_k127_890297_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
HKD1_k127_890297_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000005794 230.0
HKD1_k127_890297_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000695 226.0
HKD1_k127_890297_6 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000003246 218.0
HKD1_k127_890297_7 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000005324 195.0
HKD1_k127_890297_8 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000001542 162.0
HKD1_k127_890297_9 Membrane K08988 - - 0.00000000000000000000000000000005238 134.0
HKD1_k127_942124_0 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 475.0
HKD1_k127_942124_1 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 376.0
HKD1_k127_942124_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000001359 102.0
HKD1_k127_942124_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000004329 74.0
HKD1_k127_942124_12 Protein conserved in bacteria K09986 - - 0.000000000131 70.0
HKD1_k127_942124_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 341.0
HKD1_k127_942124_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 327.0
HKD1_k127_942124_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000112 287.0
HKD1_k127_942124_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000002728 278.0
HKD1_k127_942124_6 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000002831 262.0
HKD1_k127_942124_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000001846 204.0
HKD1_k127_942124_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000245 184.0
HKD1_k127_942124_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000001564 145.0
HKD1_k127_964153_0 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 436.0
HKD1_k127_964153_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 417.0
HKD1_k127_964153_10 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000003833 215.0
HKD1_k127_964153_11 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000004481 190.0
HKD1_k127_964153_12 COG0534 Na -driven multidrug efflux pump - - - 0.00000000000000000000000000000000000000000000004255 187.0
HKD1_k127_964153_13 Methyltransferase domain - - - 0.0000000000000000000000000000000000000003566 169.0
HKD1_k127_964153_14 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000002695 134.0
HKD1_k127_964153_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000001766 133.0
HKD1_k127_964153_16 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000001076 104.0
HKD1_k127_964153_17 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000002806 58.0
HKD1_k127_964153_18 Carboxymuconolactone decarboxylase family - - - 0.000001127 60.0
HKD1_k127_964153_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 396.0
HKD1_k127_964153_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 345.0
HKD1_k127_964153_4 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 350.0
HKD1_k127_964153_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 301.0
HKD1_k127_964153_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000007898 271.0
HKD1_k127_964153_7 Fe-S protein K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000003456 262.0
HKD1_k127_964153_8 PFAM Sulfotransferase K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000007266 238.0
HKD1_k127_964153_9 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000006996 210.0
HKD1_k127_968410_0 COG0439 Biotin carboxylase - - - 6.308e-265 873.0
HKD1_k127_968410_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 3.739e-260 862.0
HKD1_k127_968410_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000001704 191.0
HKD1_k127_968410_11 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.000000000000000000000000000000000000000001774 179.0
HKD1_k127_968410_12 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.0000000000000000001707 103.0
HKD1_k127_968410_13 pyrroloquinoline quinone binding - - - 0.0000000000000001948 94.0
HKD1_k127_968410_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00000000000001914 79.0
HKD1_k127_968410_15 HAD-hyrolase-like K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.0000000000000542 85.0
HKD1_k127_968410_16 Acetyltransferase (GNAT) domain - - - 0.00000000006621 76.0
HKD1_k127_968410_17 Sigma-54 interaction domain K10126 - - 0.000004729 60.0
HKD1_k127_968410_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.95e-219 703.0
HKD1_k127_968410_3 CoA carboxylase activity - - - 2.737e-219 694.0
HKD1_k127_968410_4 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 517.0
HKD1_k127_968410_5 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 438.0
HKD1_k127_968410_6 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 422.0
HKD1_k127_968410_7 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 380.0
HKD1_k127_968410_8 Sodium:dicarboxylate symporter family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 308.0
HKD1_k127_968410_9 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 307.0