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Overview

ID MAG01764
Name HKD1_bin.83
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family UBA5066
Genus Fen-183
Species
Assembly information
Completeness (%) 89.28
Contamination (%) 4.2
GC content (%) 72.0
N50 (bp) 27,140
Genome size (bp) 4,257,092

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3372

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1046122_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1147.0
HKD1_k127_1046122_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.22e-199 632.0
HKD1_k127_1046122_10 Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 415.0
HKD1_k127_1046122_11 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 292.0
HKD1_k127_1046122_12 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002169 293.0
HKD1_k127_1046122_13 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000809 282.0
HKD1_k127_1046122_14 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001238 281.0
HKD1_k127_1046122_15 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005359 274.0
HKD1_k127_1046122_16 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001157 263.0
HKD1_k127_1046122_17 metal cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
HKD1_k127_1046122_18 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000002706 215.0
HKD1_k127_1046122_19 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000189 172.0
HKD1_k127_1046122_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 633.0
HKD1_k127_1046122_20 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000001181 165.0
HKD1_k127_1046122_21 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000002273 147.0
HKD1_k127_1046122_22 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000001966 118.0
HKD1_k127_1046122_23 biopolymer transport protein K03559,K03560 - - 0.00000000000000000000001278 106.0
HKD1_k127_1046122_24 Tetratricopeptide repeat - - - 0.00000000000000000000001414 112.0
HKD1_k127_1046122_25 Transthyretin K07127 - 3.5.2.17 0.00000000000000000000007463 113.0
HKD1_k127_1046122_26 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000006171 98.0
HKD1_k127_1046122_27 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000005255 93.0
HKD1_k127_1046122_28 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000257 91.0
HKD1_k127_1046122_29 Tetratricopeptide repeat - - - 0.0000000000000007003 91.0
HKD1_k127_1046122_3 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 602.0
HKD1_k127_1046122_30 VanZ like family - - - 0.000002154 60.0
HKD1_k127_1046122_31 oxidoreductase activity - - - 0.00003202 57.0
HKD1_k127_1046122_32 Redoxin - - - 0.000419 52.0
HKD1_k127_1046122_33 Belongs to the ompA family K03286 - - 0.0005472 53.0
HKD1_k127_1046122_4 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 541.0
HKD1_k127_1046122_5 Amidohydrolase family K01466 - 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 525.0
HKD1_k127_1046122_6 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 466.0
HKD1_k127_1046122_7 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 475.0
HKD1_k127_1046122_8 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 453.0
HKD1_k127_1046122_9 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 411.0
HKD1_k127_1048889_0 lipopolysaccharide transport K22110 - - 0.0 1379.0
HKD1_k127_1048889_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 527.0
HKD1_k127_1048889_2 NADH dehydrogenase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 385.0
HKD1_k127_1048889_3 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 351.0
HKD1_k127_1048889_4 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000005073 186.0
HKD1_k127_1048889_5 MltA-interacting protein MipA - - - 0.00000000006366 73.0
HKD1_k127_1053612_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.349e-229 716.0
HKD1_k127_1053612_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 563.0
HKD1_k127_1053612_10 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 344.0
HKD1_k127_1053612_11 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 338.0
HKD1_k127_1053612_12 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 276.0
HKD1_k127_1053612_14 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000003839 229.0
HKD1_k127_1053612_15 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000008671 222.0
HKD1_k127_1053612_16 esterase - - - 0.00000000000000000000000000000000000000000000000000000000002823 213.0
HKD1_k127_1053612_17 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000886 221.0
HKD1_k127_1053612_18 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000003366 203.0
HKD1_k127_1053612_19 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000006195 171.0
HKD1_k127_1053612_2 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 544.0
HKD1_k127_1053612_20 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000006404 160.0
HKD1_k127_1053612_21 glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000456 163.0
HKD1_k127_1053612_22 Amidohydrolase family - - - 0.00000000000000000000000000000001188 145.0
HKD1_k127_1053612_23 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000001982 114.0
HKD1_k127_1053612_24 Protein of unknown function, DUF255 - - - 0.000000000000000006185 99.0
HKD1_k127_1053612_25 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000003621 93.0
HKD1_k127_1053612_26 Virulence activator alpha C-term - - - 0.0000000000002362 78.0
HKD1_k127_1053612_27 Putative phosphatase (DUF442) - - - 0.00000000000652 77.0
HKD1_k127_1053612_28 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000002073 71.0
HKD1_k127_1053612_29 Domain of unknown function (DUF4149) - - - 0.000009445 58.0
HKD1_k127_1053612_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 488.0
HKD1_k127_1053612_30 redox protein regulator of disulfide bond formation K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.0001268 55.0
HKD1_k127_1053612_4 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 460.0
HKD1_k127_1053612_5 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 445.0
HKD1_k127_1053612_6 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 442.0
HKD1_k127_1053612_7 Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 445.0
HKD1_k127_1053612_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 424.0
HKD1_k127_1053612_9 Cardiolipin synthetase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 354.0
HKD1_k127_1104943_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 305.0
HKD1_k127_1104943_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000006955 113.0
HKD1_k127_1104943_2 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000000000003885 104.0
HKD1_k127_1104943_3 lipolytic protein G-D-S-L family - - - 0.000000000000001016 91.0
HKD1_k127_1104943_4 - - - - 0.000002326 51.0
HKD1_k127_1152154_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 6.992e-274 872.0
HKD1_k127_1152154_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000009441 207.0
HKD1_k127_1152154_2 Squalene--hopene cyclase - - - 0.000000000000000000000000000000000000000007979 160.0
HKD1_k127_1152154_3 - - - - 0.0000000000000000000000000000000000000001043 166.0
HKD1_k127_1152154_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000005046 123.0
HKD1_k127_1152154_6 - - - - 0.0000000000000000001343 90.0
HKD1_k127_1152154_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000002249 91.0
HKD1_k127_1164654_0 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 546.0
HKD1_k127_1164654_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 559.0
HKD1_k127_1164654_10 Hfq protein - - - 0.00000000000000000000000001751 124.0
HKD1_k127_1164654_11 DinB superfamily - - - 0.0000000001097 71.0
HKD1_k127_1164654_2 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 382.0
HKD1_k127_1164654_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 346.0
HKD1_k127_1164654_4 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 320.0
HKD1_k127_1164654_5 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 284.0
HKD1_k127_1164654_6 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000149 215.0
HKD1_k127_1164654_7 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000001551 218.0
HKD1_k127_1164654_8 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000005485 170.0
HKD1_k127_1164654_9 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000004163 134.0
HKD1_k127_1180427_0 Tricorn protease homolog - - - 0.0 1384.0
HKD1_k127_1180427_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003444 281.0
HKD1_k127_1180427_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000008596 91.0
HKD1_k127_1180427_3 Ankyrin repeat K06867 - - 0.0001228 54.0
HKD1_k127_1217822_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000002828 211.0
HKD1_k127_1217822_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose - - - 0.000000000000000000000000000000000000000000000007547 183.0
HKD1_k127_122433_0 ABC transporter K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 510.0
HKD1_k127_122433_1 Sulfatase - - - 0.000000000000000000000000000000000000004798 169.0
HKD1_k127_1249089_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.254e-210 668.0
HKD1_k127_1249089_1 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 507.0
HKD1_k127_1249089_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000192 251.0
HKD1_k127_1249089_11 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001257 235.0
HKD1_k127_1249089_12 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000343 212.0
HKD1_k127_1249089_13 phosphate-selective porin K07221 - - 0.00000000000000000000000000000000000000000000000000000002547 224.0
HKD1_k127_1249089_14 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000001068 211.0
HKD1_k127_1249089_15 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000001012 201.0
HKD1_k127_1249089_16 PAS domain containing protein K02030 - - 0.000000000000000000000000000000000000000000006133 185.0
HKD1_k127_1249089_17 Ppx/GppA phosphatase family - - - 0.00000000000000000000000000000000000008542 150.0
HKD1_k127_1249089_18 methylamine metabolic process - - - 0.00000000000000000000000000000007781 140.0
HKD1_k127_1249089_19 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.00000000000000000000000001043 120.0
HKD1_k127_1249089_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 435.0
HKD1_k127_1249089_20 Belongs to the Fur family K09825 - - 0.0000000000000000000000001987 108.0
HKD1_k127_1249089_21 diguanylate cyclase - - - 0.000000000000000009968 99.0
HKD1_k127_1249089_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 398.0
HKD1_k127_1249089_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 391.0
HKD1_k127_1249089_5 Di- and tricarboxylate transporters K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 366.0
HKD1_k127_1249089_6 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 356.0
HKD1_k127_1249089_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 306.0
HKD1_k127_1249089_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
HKD1_k127_1249089_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003304 254.0
HKD1_k127_1271757_0 PFAM Prolyl oligopeptidase family - - - 1.022e-245 775.0
HKD1_k127_1271757_1 imidazolonepropionase activity K01443 - 3.5.1.25 9.302e-216 707.0
HKD1_k127_1271757_2 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005152 253.0
HKD1_k127_1271757_3 PDZ domain (Also known as DHR or GLGF) - - - 0.00000000000000000000000000007518 125.0
HKD1_k127_1296738_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 499.0
HKD1_k127_1296738_1 Magnesium chelatase, subunit ChlI K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 473.0
HKD1_k127_1296738_2 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000333 267.0
HKD1_k127_1296738_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000005845 256.0
HKD1_k127_1296738_4 Transglycosylase SLT domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000003208 256.0
HKD1_k127_1296738_5 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000005934 167.0
HKD1_k127_1318994_0 Cohesin domain K02453 - - 0.000000000000000000000000000000000000000000000000000000000001045 231.0
HKD1_k127_1318994_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000002045 220.0
HKD1_k127_1318994_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000004647 196.0
HKD1_k127_1318994_3 beta-lactamase - - - 0.00000000000000000000000000000000000000000000004175 188.0
HKD1_k127_1318994_4 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000009137 166.0
HKD1_k127_1318994_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000005771 160.0
HKD1_k127_1318994_6 Type II secretion system protein G K02456 - - 0.000000000000000000000000000006473 130.0
HKD1_k127_1318994_7 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000001361 111.0
HKD1_k127_1318994_8 general secretion pathway protein K02456,K02650 - - 0.000000000000001017 88.0
HKD1_k127_1318994_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000005072 87.0
HKD1_k127_1355681_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 501.0
HKD1_k127_1355681_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 471.0
HKD1_k127_1355681_2 Aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 411.0
HKD1_k127_1355681_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 385.0
HKD1_k127_1355681_4 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002114 276.0
HKD1_k127_1355681_5 TM2 domain protein - - - 0.0000000000000000000002537 102.0
HKD1_k127_1355681_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000001824 73.0
HKD1_k127_1355681_7 Protein of unknown function (DUF4230) - - - 0.0000000001598 69.0
HKD1_k127_1355681_8 Tetratricopeptide repeat - - - 0.0003144 52.0
HKD1_k127_1418295_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 533.0
HKD1_k127_1418295_1 N,N-dimethylaniline monooxygenase activity K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 478.0
HKD1_k127_1418295_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 430.0
HKD1_k127_1418295_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003961 264.0
HKD1_k127_1418295_4 YHS domain protein - - - 0.00000000000000000000000000000000000000371 153.0
HKD1_k127_1418295_5 Sigma-70 region 2 K03088 - - 0.0000002447 61.0
HKD1_k127_1447054_0 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 575.0
HKD1_k127_1447054_1 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000321 226.0
HKD1_k127_1447054_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000002149 138.0
HKD1_k127_1447054_3 TIGRFAM TonB-dependent vitamin B12 receptor K16092 - - 0.00000000000000000728 98.0
HKD1_k127_1447419_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.834e-214 687.0
HKD1_k127_1447419_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.892e-198 664.0
HKD1_k127_1447419_10 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003382 263.0
HKD1_k127_1447419_11 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000006214 260.0
HKD1_k127_1447419_12 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000002058 224.0
HKD1_k127_1447419_13 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000006298 250.0
HKD1_k127_1447419_14 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000001193 223.0
HKD1_k127_1447419_15 response regulator - - - 0.000000000000000000000000000000000000000000000000000001372 209.0
HKD1_k127_1447419_16 response regulator K02481,K07715 - - 0.00000000000000000000000000000000000000000000000132 196.0
HKD1_k127_1447419_17 Ferredoxin - - - 0.000000000000000000000000000000000000000000001442 169.0
HKD1_k127_1447419_18 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000551 170.0
HKD1_k127_1447419_19 domain protein K20276 - - 0.0000000000000000000000000000000000000000005366 173.0
HKD1_k127_1447419_2 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 594.0
HKD1_k127_1447419_20 PFAM Peptidase S53, propeptide - - - 0.000000000000000000000000000000000000004623 171.0
HKD1_k127_1447419_21 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000001282 152.0
HKD1_k127_1447419_22 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000805 129.0
HKD1_k127_1447419_23 COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.00000000000000000000003323 115.0
HKD1_k127_1447419_24 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000001622 113.0
HKD1_k127_1447419_25 Thioesterase-like superfamily K07107 - - 0.00000000000000000001672 107.0
HKD1_k127_1447419_26 - - - - 0.0000000000000000001518 104.0
HKD1_k127_1447419_27 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000001549 88.0
HKD1_k127_1447419_28 polysaccharide deacetylase - - - 0.000000000002037 79.0
HKD1_k127_1447419_29 luxR family - - - 0.0000000001951 72.0
HKD1_k127_1447419_3 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 513.0
HKD1_k127_1447419_30 PilZ domain - - - 0.000297 51.0
HKD1_k127_1447419_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 399.0
HKD1_k127_1447419_5 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 389.0
HKD1_k127_1447419_6 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 377.0
HKD1_k127_1447419_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 361.0
HKD1_k127_1447419_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 331.0
HKD1_k127_1447419_9 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 318.0
HKD1_k127_1455632_0 Heat shock 70 kDa protein K04043 - - 8.89e-216 687.0
HKD1_k127_1455632_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 419.0
HKD1_k127_1455632_2 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 395.0
HKD1_k127_1455632_3 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000003051 231.0
HKD1_k127_1455632_4 XdhC Rossmann domain - - - 0.00000000000000000000000000000000000000004004 171.0
HKD1_k127_1455632_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000001003 146.0
HKD1_k127_1455632_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000000008945 136.0
HKD1_k127_1455632_7 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000134 105.0
HKD1_k127_1455632_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000008435 96.0
HKD1_k127_1455632_9 MobA-related protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000008084 72.0
HKD1_k127_1471994_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.335e-260 825.0
HKD1_k127_1471994_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 576.0
HKD1_k127_1471994_10 hydrolase of the alpha beta superfamily K07017 - - 0.000000000000000000000000000000000000000000000000000000000000000000001379 258.0
HKD1_k127_1471994_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009582 220.0
HKD1_k127_1471994_12 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000006747 196.0
HKD1_k127_1471994_13 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000005645 161.0
HKD1_k127_1471994_14 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000001382 148.0
HKD1_k127_1471994_15 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000001301 143.0
HKD1_k127_1471994_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000001882 142.0
HKD1_k127_1471994_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000004221 132.0
HKD1_k127_1471994_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000006551 93.0
HKD1_k127_1471994_19 Heavy-metal resistance - - - 0.00000000000001488 85.0
HKD1_k127_1471994_2 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 559.0
HKD1_k127_1471994_20 polysaccharide deacetylase - - - 0.00000000001235 76.0
HKD1_k127_1471994_21 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000001037 62.0
HKD1_k127_1471994_22 mRNA catabolic process K06950 - - 0.0003688 54.0
HKD1_k127_1471994_3 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 515.0
HKD1_k127_1471994_4 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 512.0
HKD1_k127_1471994_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 485.0
HKD1_k127_1471994_6 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 409.0
HKD1_k127_1471994_7 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 423.0
HKD1_k127_1471994_8 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008046 285.0
HKD1_k127_1471994_9 ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000003548 263.0
HKD1_k127_1495746_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1211.0
HKD1_k127_1495746_1 beta-lactamase - - - 1.402e-215 695.0
HKD1_k127_1495746_10 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000003687 194.0
HKD1_k127_1495746_11 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000002934 173.0
HKD1_k127_1495746_12 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000001653 169.0
HKD1_k127_1495746_13 DinB family - - - 0.000000000000000000000000000000000000000002811 163.0
HKD1_k127_1495746_14 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000008191 142.0
HKD1_k127_1495746_15 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000008568 131.0
HKD1_k127_1495746_16 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000003827 115.0
HKD1_k127_1495746_17 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000001266 100.0
HKD1_k127_1495746_18 - - - - 0.00000000001476 77.0
HKD1_k127_1495746_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 547.0
HKD1_k127_1495746_3 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 497.0
HKD1_k127_1495746_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 357.0
HKD1_k127_1495746_5 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 353.0
HKD1_k127_1495746_6 Acetamidase formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 327.0
HKD1_k127_1495746_7 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000032 293.0
HKD1_k127_1495746_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009347 249.0
HKD1_k127_1495746_9 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000002438 237.0
HKD1_k127_1516672_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 438.0
HKD1_k127_1516672_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 387.0
HKD1_k127_1516672_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000007843 212.0
HKD1_k127_1516672_3 - - - - 0.000000000000000000000000002995 127.0
HKD1_k127_1516672_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000006187 100.0
HKD1_k127_1516672_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000003803 90.0
HKD1_k127_1516672_6 Response regulator receiver domain - - - 0.00000000000000001704 97.0
HKD1_k127_160660_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 2.701e-280 880.0
HKD1_k127_160660_1 ABC transporter K06020 - 3.6.3.25 4.803e-253 793.0
HKD1_k127_160660_10 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 308.0
HKD1_k127_160660_11 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K02549,K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 4.2.1.113,5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004608 289.0
HKD1_k127_160660_12 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000755 267.0
HKD1_k127_160660_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002676 245.0
HKD1_k127_160660_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000001904 226.0
HKD1_k127_160660_15 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000000000000000000000000006884 216.0
HKD1_k127_160660_16 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000001466 227.0
HKD1_k127_160660_17 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000006058 226.0
HKD1_k127_160660_18 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000008632 209.0
HKD1_k127_160660_19 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000348 201.0
HKD1_k127_160660_2 Prolyl oligopeptidase family - - - 2.144e-218 698.0
HKD1_k127_160660_20 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000001173 179.0
HKD1_k127_160660_21 NlpC/P60 family - - - 0.0000000000000000000000000000000001241 152.0
HKD1_k127_160660_22 Ami_2 K00788,K01447,K03806,K11066 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 0.00000000000000000000000001459 126.0
HKD1_k127_160660_23 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000004371 121.0
HKD1_k127_160660_24 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000002659 112.0
HKD1_k127_160660_25 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000421 102.0
HKD1_k127_160660_26 Domain of unknown function (DUF4440) - - - 0.00000000000000006554 87.0
HKD1_k127_160660_27 Transglycosylase associated protein - - - 0.00000000000002307 75.0
HKD1_k127_160660_29 - - - - 0.0000000444 68.0
HKD1_k127_160660_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 563.0
HKD1_k127_160660_30 - - - - 0.00006021 50.0
HKD1_k127_160660_4 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 526.0
HKD1_k127_160660_5 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 426.0
HKD1_k127_160660_6 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 356.0
HKD1_k127_160660_7 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 326.0
HKD1_k127_160660_8 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 313.0
HKD1_k127_160660_9 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 303.0
HKD1_k127_1640441_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 545.0
HKD1_k127_1640441_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 496.0
HKD1_k127_1640441_10 TonB-dependent receptor - - - 0.000000006802 67.0
HKD1_k127_1640441_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000005864 59.0
HKD1_k127_1640441_12 Acetyltransferase (GNAT) domain - - - 0.00000878 59.0
HKD1_k127_1640441_13 Putative zinc-finger - - - 0.00008807 55.0
HKD1_k127_1640441_2 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 376.0
HKD1_k127_1640441_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000142 308.0
HKD1_k127_1640441_4 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000005696 266.0
HKD1_k127_1640441_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000117 248.0
HKD1_k127_1640441_6 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000371 192.0
HKD1_k127_1640441_7 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000001262 170.0
HKD1_k127_1640441_8 glyoxalase III activity - - - 0.00000000002054 70.0
HKD1_k127_1640441_9 Peptidase M56, BlaR1 - - - 0.000000002336 70.0
HKD1_k127_169608_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 550.0
HKD1_k127_169608_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 560.0
HKD1_k127_169608_10 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009536 254.0
HKD1_k127_169608_11 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001109 240.0
HKD1_k127_169608_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002115 229.0
HKD1_k127_169608_13 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000479 240.0
HKD1_k127_169608_14 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000005167 208.0
HKD1_k127_169608_15 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000001817 193.0
HKD1_k127_169608_16 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000002004 181.0
HKD1_k127_169608_17 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000000000003226 162.0
HKD1_k127_169608_18 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000001019 171.0
HKD1_k127_169608_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000132 153.0
HKD1_k127_169608_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 534.0
HKD1_k127_169608_20 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000004242 134.0
HKD1_k127_169608_21 HupE / UreJ protein - - - 0.000000000000000000000000000000005911 143.0
HKD1_k127_169608_22 G-D-S-L family - - - 0.000000000000000000000000000002189 130.0
HKD1_k127_169608_23 Fumble K09680 - 2.7.1.33 0.000000000000000000000000000002483 133.0
HKD1_k127_169608_25 oxidoreductase activity - - - 0.000000000000000000009568 107.0
HKD1_k127_169608_27 - - - - 0.0000000005851 73.0
HKD1_k127_169608_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 484.0
HKD1_k127_169608_4 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 394.0
HKD1_k127_169608_5 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
HKD1_k127_169608_6 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 323.0
HKD1_k127_169608_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
HKD1_k127_169608_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009711 266.0
HKD1_k127_169608_9 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002243 263.0
HKD1_k127_1717428_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 8.15e-322 1010.0
HKD1_k127_1717428_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 574.0
HKD1_k127_1717428_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 388.0
HKD1_k127_1717428_3 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 345.0
HKD1_k127_1717428_4 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 308.0
HKD1_k127_1717428_5 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000005123 141.0
HKD1_k127_1717428_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000001654 143.0
HKD1_k127_1717428_7 cobalamin synthesis protein, P47K - GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000003103 80.0
HKD1_k127_1835488_0 PFAM GlcNAc-PI de-N-acetylase - - - 5.808e-246 811.0
HKD1_k127_1835488_1 transcription factor binding K02584 - - 2.725e-205 653.0
HKD1_k127_1835488_2 PFAM major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 317.0
HKD1_k127_1835488_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003958 244.0
HKD1_k127_1835488_4 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000008761 196.0
HKD1_k127_1835488_5 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000001268 193.0
HKD1_k127_1835488_6 DinB superfamily - - - 0.0000000000000000000000000000000000002034 147.0
HKD1_k127_1835488_7 SBF-like CPA transporter family (DUF4137) K03453 - - 0.000000000000000000000000005028 121.0
HKD1_k127_1835488_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000002815 109.0
HKD1_k127_1835488_9 CAAX protease self-immunity K07052 - - 0.0000000002291 71.0
HKD1_k127_1845885_0 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 375.0
HKD1_k127_1845885_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 350.0
HKD1_k127_1845885_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000004492 138.0
HKD1_k127_195659_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 333.0
HKD1_k127_195659_1 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 314.0
HKD1_k127_195659_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000003552 143.0
HKD1_k127_195659_3 Amino acid permease K03294 - - 0.00000003009 63.0
HKD1_k127_2077588_0 Phospholipase D. Active site motifs. - - - 1.054e-243 771.0
HKD1_k127_2077588_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001409 248.0
HKD1_k127_2077588_2 Lipase (class 3) K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000001337 211.0
HKD1_k127_2077588_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000001189 143.0
HKD1_k127_2077588_4 translation initiation inhibitor, yjgF family K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000001474 109.0
HKD1_k127_2092452_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 351.0
HKD1_k127_2092452_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 328.0
HKD1_k127_2092452_10 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000003924 114.0
HKD1_k127_2092452_2 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004844 273.0
HKD1_k127_2092452_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000491 275.0
HKD1_k127_2092452_4 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000001944 246.0
HKD1_k127_2092452_5 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001053 240.0
HKD1_k127_2092452_6 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000001504 246.0
HKD1_k127_2092452_7 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000004022 163.0
HKD1_k127_2092452_8 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000003889 140.0
HKD1_k127_2092452_9 tRNA wobble adenosine to inosine editing - - - 0.000000000000000000000000003984 131.0
HKD1_k127_2094967_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1258.0
HKD1_k127_2094967_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1257.0
HKD1_k127_2094967_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 536.0
HKD1_k127_2094967_12 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 497.0
HKD1_k127_2094967_13 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 450.0
HKD1_k127_2094967_14 Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 421.0
HKD1_k127_2094967_15 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 443.0
HKD1_k127_2094967_16 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 434.0
HKD1_k127_2094967_17 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 392.0
HKD1_k127_2094967_18 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 379.0
HKD1_k127_2094967_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1084.0
HKD1_k127_2094967_20 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 350.0
HKD1_k127_2094967_21 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 340.0
HKD1_k127_2094967_22 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 316.0
HKD1_k127_2094967_23 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 332.0
HKD1_k127_2094967_24 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 326.0
HKD1_k127_2094967_25 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 305.0
HKD1_k127_2094967_26 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000005426 246.0
HKD1_k127_2094967_28 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000001251 146.0
HKD1_k127_2094967_29 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000005449 134.0
HKD1_k127_2094967_3 Involved in the tonB-independent uptake of proteins - - - 1.121e-259 818.0
HKD1_k127_2094967_30 Tetratricopeptide repeat - - - 0.0000000000000000000000003665 113.0
HKD1_k127_2094967_31 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.00000000000000000000001997 108.0
HKD1_k127_2094967_32 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000008717 101.0
HKD1_k127_2094967_33 Rhomboid family - - - 0.0000000000000001006 94.0
HKD1_k127_2094967_34 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.0000000006735 74.0
HKD1_k127_2094967_35 Cupin 2, conserved barrel domain protein - - - 0.0000002191 60.0
HKD1_k127_2094967_36 - - - - 0.0001042 53.0
HKD1_k127_2094967_37 CHAT domain - - - 0.0007905 52.0
HKD1_k127_2094967_4 PFAM Protein synthesis factor, GTP-binding K06207 - - 4.731e-241 781.0
HKD1_k127_2094967_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 598.0
HKD1_k127_2094967_6 RNB K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 606.0
HKD1_k127_2094967_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 560.0
HKD1_k127_2094967_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 567.0
HKD1_k127_2094967_9 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 563.0
HKD1_k127_2111182_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 375.0
HKD1_k127_2111182_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 362.0
HKD1_k127_2111182_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001441 252.0
HKD1_k127_2111182_3 KR domain K07124 - - 0.0000000000000000000000000000000000000000008707 176.0
HKD1_k127_2111182_4 GDP-mannose mannosyl hydrolase activity - - - 0.0000000000000000000000000000000001416 138.0
HKD1_k127_2111182_5 peptidyl-tyrosine sulfation - - - 0.000000000000002114 85.0
HKD1_k127_2111182_6 Protein of unknown function, DUF547 - - - 0.0000002656 58.0
HKD1_k127_2119168_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 481.0
HKD1_k127_2119168_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 458.0
HKD1_k127_2119168_10 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.00000000000000000002145 98.0
HKD1_k127_2119168_2 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 402.0
HKD1_k127_2119168_3 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 320.0
HKD1_k127_2119168_4 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004245 292.0
HKD1_k127_2119168_5 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000005897 217.0
HKD1_k127_2119168_6 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000001643 212.0
HKD1_k127_2119168_7 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000002267 204.0
HKD1_k127_2119168_8 anion-transporting ATPase - - - 0.0000000000000000000000000000000000000000009728 178.0
HKD1_k127_2119168_9 Anion-transporting ATPase - - - 0.000000000000000000000000002267 129.0
HKD1_k127_2120382_0 Tricorn protease homolog K08676 - - 8.883e-321 1050.0
HKD1_k127_2120382_1 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 9.86e-232 730.0
HKD1_k127_2120382_10 Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA K06969 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.191 0.0000000000000000000000000000000000000000000000000000003262 205.0
HKD1_k127_2120382_11 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000001785 195.0
HKD1_k127_2120382_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000005933 215.0
HKD1_k127_2120382_13 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000001847 198.0
HKD1_k127_2120382_14 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000006705 158.0
HKD1_k127_2120382_15 catalyzes the methylation of cytosine at position 1962 of the 23S rRNA K06969 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.191 0.0000000000000000000000000000000002824 135.0
HKD1_k127_2120382_16 DinB family - - - 0.0000000000000000000000000000002629 132.0
HKD1_k127_2120382_17 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000009078 116.0
HKD1_k127_2120382_18 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000004982 106.0
HKD1_k127_2120382_19 PFAM General secretory system II protein E domain protein - - - 0.00000003319 65.0
HKD1_k127_2120382_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 556.0
HKD1_k127_2120382_20 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00003126 50.0
HKD1_k127_2120382_3 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 493.0
HKD1_k127_2120382_4 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 491.0
HKD1_k127_2120382_5 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 415.0
HKD1_k127_2120382_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 341.0
HKD1_k127_2120382_7 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 335.0
HKD1_k127_2120382_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009691 267.0
HKD1_k127_2120382_9 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000003238 227.0
HKD1_k127_2126578_0 peptidase K01415,K07386 - 3.4.24.71 1.613e-281 881.0
HKD1_k127_2126578_1 Involved in the tonB-independent uptake of proteins - - - 1.19e-200 660.0
HKD1_k127_2126578_10 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 384.0
HKD1_k127_2126578_11 Alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001031 273.0
HKD1_k127_2126578_12 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000001303 248.0
HKD1_k127_2126578_13 Major Facilitator Superfamily K03535 - - 0.00000000000000000000000000000000000000000000000000000000000000001974 245.0
HKD1_k127_2126578_14 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000169 207.0
HKD1_k127_2126578_15 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000002671 177.0
HKD1_k127_2126578_16 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000000000001038 139.0
HKD1_k127_2126578_17 Membrane K08988 - - 0.0000000000000000000000005452 121.0
HKD1_k127_2126578_18 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000002616 112.0
HKD1_k127_2126578_19 - - - - 0.0000000000000000001877 95.0
HKD1_k127_2126578_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 3.925e-198 639.0
HKD1_k127_2126578_20 acetyltransferase - - - 0.0000000000000000009809 102.0
HKD1_k127_2126578_21 PFAM glycoside hydrolase family 39 K21000 - - 0.000000000000007021 83.0
HKD1_k127_2126578_23 SnoaL-like domain - - - 0.00000002092 66.0
HKD1_k127_2126578_24 Lysin motif - - - 0.00008228 53.0
HKD1_k127_2126578_26 TPM domain K06872 - - 0.0003814 53.0
HKD1_k127_2126578_27 Baseplate J-like protein - - - 0.0004094 51.0
HKD1_k127_2126578_3 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 497.0
HKD1_k127_2126578_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 452.0
HKD1_k127_2126578_5 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 501.0
HKD1_k127_2126578_6 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 443.0
HKD1_k127_2126578_7 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 468.0
HKD1_k127_2126578_8 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 440.0
HKD1_k127_2126578_9 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 385.0
HKD1_k127_2133701_0 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 383.0
HKD1_k127_2133701_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 371.0
HKD1_k127_2133701_2 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000000000000000000000000001061 207.0
HKD1_k127_2133701_3 metallopeptidase activity K00571,K01126,K01176 - 2.1.1.72,3.1.4.46,3.2.1.1 0.0000000000000000000000000000000000001356 151.0
HKD1_k127_2133701_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000002087 132.0
HKD1_k127_2133701_5 Resolvase - - - 0.0000017 50.0
HKD1_k127_2133701_6 protein-disulfide reductase activity - - - 0.00009621 53.0
HKD1_k127_2171727_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 447.0
HKD1_k127_2171727_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 332.0
HKD1_k127_2171727_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 317.0
HKD1_k127_2171727_3 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000764 133.0
HKD1_k127_2171727_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000001352 87.0
HKD1_k127_2171727_5 OmpA family - - - 0.000000000005188 73.0
HKD1_k127_2171727_6 Thioredoxin-like - - - 0.000005548 51.0
HKD1_k127_2171727_7 Glucose sorbosone - - - 0.000009392 60.0
HKD1_k127_2171727_8 exo-alpha-(2->6)-sialidase activity - - - 0.00002819 59.0
HKD1_k127_2173485_0 Phosphoglycerate mutase family - - - 0.00000000000000000000000002309 118.0
HKD1_k127_2200890_0 Peptidase S46 - - - 6.788e-301 942.0
HKD1_k127_2200890_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 595.0
HKD1_k127_2200890_10 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.000000000000000000000000000000000001538 161.0
HKD1_k127_2200890_11 Citrate transporter - - - 0.00000000000000000000000000002948 132.0
HKD1_k127_2200890_12 - - - - 0.0000000000000000000000000004094 125.0
HKD1_k127_2200890_13 the in vivo substrate is - - - 0.00000000000000000000002054 113.0
HKD1_k127_2200890_14 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000001373 105.0
HKD1_k127_2200890_15 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000001148 94.0
HKD1_k127_2200890_16 FecR protein - - - 0.00004176 56.0
HKD1_k127_2200890_17 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - 0.00007884 45.0
HKD1_k127_2200890_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 566.0
HKD1_k127_2200890_3 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 525.0
HKD1_k127_2200890_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 420.0
HKD1_k127_2200890_5 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 436.0
HKD1_k127_2200890_6 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000005363 276.0
HKD1_k127_2200890_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 252.0
HKD1_k127_2200890_8 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000001063 228.0
HKD1_k127_2200890_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000002252 173.0
HKD1_k127_2206210_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 376.0
HKD1_k127_2206210_1 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
HKD1_k127_2206210_10 - - - - 0.000006764 51.0
HKD1_k127_2206210_2 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003035 279.0
HKD1_k127_2206210_3 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000293 181.0
HKD1_k127_2206210_4 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000006036 158.0
HKD1_k127_2206210_5 Serine hydrolase involved in the detoxification of formaldehyde K01070,K07214 - 3.1.2.12 0.0000000000000000000000000006354 124.0
HKD1_k127_2206210_6 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000008529 110.0
HKD1_k127_2206210_7 - - - - 0.000000000009326 75.0
HKD1_k127_2206210_8 DoxX - - - 0.0000000001443 63.0
HKD1_k127_2208331_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001587 262.0
HKD1_k127_2208331_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000009376 241.0
HKD1_k127_2208331_2 - - - - 0.0000000000000000000000000000000002093 149.0
HKD1_k127_2208331_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000013 53.0
HKD1_k127_2213609_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 3.767e-255 803.0
HKD1_k127_2213609_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 350.0
HKD1_k127_2213609_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000005861 226.0
HKD1_k127_2213609_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000004626 141.0
HKD1_k127_2213609_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000752 143.0
HKD1_k127_2213609_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000004194 115.0
HKD1_k127_2213609_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000006407 107.0
HKD1_k127_2213609_7 TPM domain - - - 0.000000000000000000000006132 108.0
HKD1_k127_2213609_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000003692 108.0
HKD1_k127_2216111_0 Involved in the tonB-independent uptake of proteins - - - 1.784e-220 712.0
HKD1_k127_2216111_1 COG0520 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 357.0
HKD1_k127_2216111_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 344.0
HKD1_k127_2217671_0 Peptidase, M16 K07263 - - 8.124e-247 792.0
HKD1_k127_2217671_1 AcrB/AcrD/AcrF family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 654.0
HKD1_k127_2217671_10 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 419.0
HKD1_k127_2217671_11 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 426.0
HKD1_k127_2217671_12 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 402.0
HKD1_k127_2217671_13 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 347.0
HKD1_k127_2217671_14 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 342.0
HKD1_k127_2217671_15 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 327.0
HKD1_k127_2217671_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 320.0
HKD1_k127_2217671_17 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 322.0
HKD1_k127_2217671_18 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 318.0
HKD1_k127_2217671_19 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
HKD1_k127_2217671_2 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 603.0
HKD1_k127_2217671_20 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 303.0
HKD1_k127_2217671_21 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 315.0
HKD1_k127_2217671_22 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 293.0
HKD1_k127_2217671_23 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 287.0
HKD1_k127_2217671_24 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002799 294.0
HKD1_k127_2217671_25 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001009 284.0
HKD1_k127_2217671_26 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001042 280.0
HKD1_k127_2217671_27 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002655 297.0
HKD1_k127_2217671_28 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001811 247.0
HKD1_k127_2217671_29 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000001003 242.0
HKD1_k127_2217671_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 598.0
HKD1_k127_2217671_30 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000003165 212.0
HKD1_k127_2217671_31 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000001197 223.0
HKD1_k127_2217671_32 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000001713 223.0
HKD1_k127_2217671_33 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000002118 180.0
HKD1_k127_2217671_34 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000004123 174.0
HKD1_k127_2217671_36 - - - - 0.00000000000000000000000000000000000000001798 162.0
HKD1_k127_2217671_37 - - - - 0.00000000000000000000000000000000000000004855 174.0
HKD1_k127_2217671_38 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000002095 169.0
HKD1_k127_2217671_39 PFAM ABC-3 protein K09816,K09819,K19976 - - 0.0000000000000000000000000000000000000002399 168.0
HKD1_k127_2217671_4 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 582.0
HKD1_k127_2217671_40 Chaperone of endosialidase - - - 0.000000000000000000000000000000000007217 157.0
HKD1_k127_2217671_41 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000003087 151.0
HKD1_k127_2217671_42 - - - - 0.0000000000000000000000000000008665 139.0
HKD1_k127_2217671_43 Belongs to the Fur family K03711 - - 0.000000000000000000000000000001032 130.0
HKD1_k127_2217671_44 ATPases associated with a variety of cellular activities K09820 - - 0.00000000000000000000000000004199 129.0
HKD1_k127_2217671_45 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000001597 134.0
HKD1_k127_2217671_46 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000004017 113.0
HKD1_k127_2217671_47 SCO1/SenC K07152 - - 0.000000000000000007622 91.0
HKD1_k127_2217671_48 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000002395 79.0
HKD1_k127_2217671_49 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000001489 88.0
HKD1_k127_2217671_5 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 574.0
HKD1_k127_2217671_50 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000005476 86.0
HKD1_k127_2217671_52 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000267 69.0
HKD1_k127_2217671_53 domain protein - - - 0.00000009582 66.0
HKD1_k127_2217671_54 Outer membrane lipoprotein-sorting protein - - - 0.000002003 61.0
HKD1_k127_2217671_55 RND efflux system, outer membrane lipoprotein K18300 - - 0.000004207 59.0
HKD1_k127_2217671_56 ig-like, plexins, transcription factors - - - 0.000287 54.0
HKD1_k127_2217671_57 ABC transporter, ATP-binding protein K06158 - - 0.0003156 48.0
HKD1_k127_2217671_6 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 537.0
HKD1_k127_2217671_7 PFAM Aldehyde dehydrogenase family K00128,K00140 - 1.2.1.18,1.2.1.27,1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 516.0
HKD1_k127_2217671_8 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 477.0
HKD1_k127_2217671_9 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 480.0
HKD1_k127_2231201_0 amino acid K03294 - - 2.369e-261 815.0
HKD1_k127_2231201_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 471.0
HKD1_k127_2231201_11 Protein of unknown function (DUF2723) - - - 0.0001472 55.0
HKD1_k127_2231201_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 368.0
HKD1_k127_2231201_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 321.0
HKD1_k127_2231201_4 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002999 297.0
HKD1_k127_2231201_5 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000003413 249.0
HKD1_k127_2231201_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000003254 170.0
HKD1_k127_2231201_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000001927 168.0
HKD1_k127_2231201_8 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000001742 124.0
HKD1_k127_2231201_9 Belongs to the universal stress protein A family - - - 0.0000000000000004392 85.0
HKD1_k127_2248284_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 395.0
HKD1_k127_2248284_1 peptidase inhibitor activity - - - 0.0000000000000000000001619 107.0
HKD1_k127_2263236_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.185e-212 679.0
HKD1_k127_2263236_1 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 519.0
HKD1_k127_2263236_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000004813 147.0
HKD1_k127_2263236_11 Thioredoxin - - - 0.000000000000000000000000000004303 135.0
HKD1_k127_2263236_12 O-Antigen ligase K18814 - - 0.00000000000000000000000000005165 131.0
HKD1_k127_2263236_13 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000001375 81.0
HKD1_k127_2263236_14 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000001553 77.0
HKD1_k127_2263236_15 Belongs to the UPF0434 family K09791 - - 0.0000000113 59.0
HKD1_k127_2263236_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000009499 64.0
HKD1_k127_2263236_17 Glycosyltransferase family 87 K13671 - - 0.0000001256 64.0
HKD1_k127_2263236_18 Flagellar rod assembly protein muramidase FlgJ - - - 0.0000001856 60.0
HKD1_k127_2263236_2 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 439.0
HKD1_k127_2263236_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 344.0
HKD1_k127_2263236_4 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 360.0
HKD1_k127_2263236_5 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002931 297.0
HKD1_k127_2263236_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000603 279.0
HKD1_k127_2263236_7 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000002496 268.0
HKD1_k127_2263236_8 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002497 229.0
HKD1_k127_2263236_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.00000000000000000000000000000000000000000000001442 177.0
HKD1_k127_2271910_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.09e-279 888.0
HKD1_k127_2271910_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 409.0
HKD1_k127_2271910_10 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000005153 138.0
HKD1_k127_2271910_11 Transmembrane and TPR repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.00000000000000000002053 107.0
HKD1_k127_2271910_12 Transcriptional regulator K05804 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000004733 106.0
HKD1_k127_2271910_13 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000001615 76.0
HKD1_k127_2271910_14 Belongs to the small heat shock protein (HSP20) K13993 - - 0.00000000002535 74.0
HKD1_k127_2271910_15 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000001293 70.0
HKD1_k127_2271910_16 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000001629 67.0
HKD1_k127_2271910_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 353.0
HKD1_k127_2271910_3 Erythromycin esterase K06880 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 373.0
HKD1_k127_2271910_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 336.0
HKD1_k127_2271910_5 PFAM Binding-protein-dependent transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 290.0
HKD1_k127_2271910_6 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000006429 229.0
HKD1_k127_2271910_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000293 221.0
HKD1_k127_2271910_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000003293 186.0
HKD1_k127_2271910_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000005175 205.0
HKD1_k127_2289297_0 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 4.026e-308 968.0
HKD1_k127_2289297_1 DEAD DEAH box helicase - - - 5.6e-264 838.0
HKD1_k127_2289297_10 TIGRFAM autotransporter-associated beta strand repeat protein K09474 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 312.0
HKD1_k127_2289297_11 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 301.0
HKD1_k127_2289297_12 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000002052 230.0
HKD1_k127_2289297_13 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000003041 195.0
HKD1_k127_2289297_14 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000001262 193.0
HKD1_k127_2289297_15 - - - - 0.000000000000000000000000000000000000000000002744 183.0
HKD1_k127_2289297_16 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000008964 159.0
HKD1_k127_2289297_17 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000001874 124.0
HKD1_k127_2289297_18 - - - - 0.0000000000000000000000000003414 120.0
HKD1_k127_2289297_19 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000003876 90.0
HKD1_k127_2289297_2 Protein kinase domain K12132 - 2.7.11.1 4.258e-253 811.0
HKD1_k127_2289297_20 - - - - 0.000000000002955 76.0
HKD1_k127_2289297_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.847e-226 717.0
HKD1_k127_2289297_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 454.0
HKD1_k127_2289297_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 380.0
HKD1_k127_2289297_6 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 360.0
HKD1_k127_2289297_7 domain, Protein K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 366.0
HKD1_k127_2289297_8 Acid phosphatase homologues K09474 - 3.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000998 326.0
HKD1_k127_2289297_9 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 330.0
HKD1_k127_2311785_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1032.0
HKD1_k127_2311785_1 Fumarase C-terminus K01676 - 4.2.1.2 2.06e-253 792.0
HKD1_k127_2311785_10 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000582 117.0
HKD1_k127_2311785_11 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000001042 111.0
HKD1_k127_2311785_13 bacterial OsmY and nodulation domain - - - 0.000000000000009275 83.0
HKD1_k127_2311785_14 Redoxin K03564 - 1.11.1.15 0.000000000000009605 77.0
HKD1_k127_2311785_15 Bacterioferritin comigratory K03564 - 1.11.1.15 0.000000000001086 70.0
HKD1_k127_2311785_16 polysaccharide deacetylase - - - 0.0000000002503 73.0
HKD1_k127_2311785_17 Bacteriophage replication gene A protein (GPA) - - - 0.000000002996 62.0
HKD1_k127_2311785_18 AntiSigma factor - - - 0.00001434 57.0
HKD1_k127_2311785_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 6.183e-229 734.0
HKD1_k127_2311785_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 540.0
HKD1_k127_2311785_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 431.0
HKD1_k127_2311785_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 331.0
HKD1_k127_2311785_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 325.0
HKD1_k127_2311785_7 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.00000000000000000000000000000000000000000000000001075 198.0
HKD1_k127_2311785_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000003976 173.0
HKD1_k127_2311785_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000003117 147.0
HKD1_k127_2340417_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 536.0
HKD1_k127_2340417_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 347.0
HKD1_k127_2401823_0 PFAM peptidase M13 K01415 - 3.4.24.71 3.238e-260 817.0
HKD1_k127_2401823_1 PFAM Sodium sulphate symporter K03319,K11106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 603.0
HKD1_k127_2401823_10 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000325 150.0
HKD1_k127_2401823_11 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000005025 155.0
HKD1_k127_2401823_12 MlaD protein K02067 - - 0.00000000000000000000000000000000000567 151.0
HKD1_k127_2401823_13 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000002493 141.0
HKD1_k127_2401823_14 chitinase K01183 - 3.2.1.14 0.000000000001072 79.0
HKD1_k127_2401823_15 diguanylate cyclase - - - 0.000000000008543 77.0
HKD1_k127_2401823_16 COG0451 Nucleoside-diphosphate-sugar epimerases K08679,K17947 - 5.1.3.25,5.1.3.6 0.000000000133 75.0
HKD1_k127_2401823_17 general secretion pathway protein - - - 0.000000005379 68.0
HKD1_k127_2401823_18 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0001915 55.0
HKD1_k127_2401823_2 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 523.0
HKD1_k127_2401823_3 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 494.0
HKD1_k127_2401823_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 351.0
HKD1_k127_2401823_5 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 321.0
HKD1_k127_2401823_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000003591 238.0
HKD1_k127_2401823_7 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000004328 251.0
HKD1_k127_2401823_8 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001141 178.0
HKD1_k127_2401823_9 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000003381 150.0
HKD1_k127_2434797_0 Heat shock 70 kDa protein K04043 - - 3.998e-297 923.0
HKD1_k127_2434797_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 9.156e-241 760.0
HKD1_k127_2434797_10 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000138 199.0
HKD1_k127_2434797_11 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000754 195.0
HKD1_k127_2434797_12 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000004701 168.0
HKD1_k127_2434797_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000007207 158.0
HKD1_k127_2434797_14 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000003093 156.0
HKD1_k127_2434797_15 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000002692 121.0
HKD1_k127_2434797_16 Peptidase family M23 K21471 - - 0.0000000000000000000006194 97.0
HKD1_k127_2434797_17 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000003841 94.0
HKD1_k127_2434797_18 Tetratricopeptide repeat - - - 0.00000000000000002088 97.0
HKD1_k127_2434797_19 - - - - 0.0000002079 59.0
HKD1_k127_2434797_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 509.0
HKD1_k127_2434797_20 Domain of unknown function (DUF1844) - - - 0.000006796 55.0
HKD1_k127_2434797_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 505.0
HKD1_k127_2434797_4 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 325.0
HKD1_k127_2434797_5 PFAM ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005751 299.0
HKD1_k127_2434797_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000001848 225.0
HKD1_k127_2434797_7 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000002215 228.0
HKD1_k127_2434797_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000006666 203.0
HKD1_k127_2434797_9 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000001128 205.0
HKD1_k127_2437915_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 453.0
HKD1_k127_2437915_1 alpha beta K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 326.0
HKD1_k127_2437915_2 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000005915 244.0
HKD1_k127_2437915_3 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000000000003682 171.0
HKD1_k127_2437915_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000545 147.0
HKD1_k127_24525_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 512.0
HKD1_k127_24525_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 432.0
HKD1_k127_24525_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.00000000000000000000000000000000000000000000000000000000000001807 226.0
HKD1_k127_24525_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000006322 196.0
HKD1_k127_24525_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000543 176.0
HKD1_k127_24525_13 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000002295 173.0
HKD1_k127_24525_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000002721 164.0
HKD1_k127_24525_15 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000004425 151.0
HKD1_k127_24525_16 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000000009561 153.0
HKD1_k127_24525_17 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000004456 146.0
HKD1_k127_24525_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000007299 137.0
HKD1_k127_24525_19 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000002873 140.0
HKD1_k127_24525_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 365.0
HKD1_k127_24525_20 Aminotransferase class-V - - - 0.00000000000000000000004563 102.0
HKD1_k127_24525_21 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000001199 91.0
HKD1_k127_24525_22 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000001274 81.0
HKD1_k127_24525_23 - - - - 0.00000004613 63.0
HKD1_k127_24525_24 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000001012 57.0
HKD1_k127_24525_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 359.0
HKD1_k127_24525_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
HKD1_k127_24525_5 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 349.0
HKD1_k127_24525_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 310.0
HKD1_k127_24525_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 301.0
HKD1_k127_24525_8 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001777 282.0
HKD1_k127_24525_9 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
HKD1_k127_245890_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1065.0
HKD1_k127_245890_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 447.0
HKD1_k127_245890_10 HI0933-like protein K07007 - - 0.000000000000000000000001973 104.0
HKD1_k127_245890_11 RF-1 domain K15034 - - 0.0000000000000000000000168 108.0
HKD1_k127_245890_12 Peptidase family M28 - - - 0.0000000000000001656 94.0
HKD1_k127_245890_13 - - - - 0.00000003991 67.0
HKD1_k127_245890_14 23S rRNA-intervening sequence protein - - - 0.0004153 49.0
HKD1_k127_245890_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 400.0
HKD1_k127_245890_3 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 399.0
HKD1_k127_245890_4 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 315.0
HKD1_k127_245890_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004171 297.0
HKD1_k127_245890_6 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000003989 224.0
HKD1_k127_245890_7 - - - - 0.000000000000000000000000000002293 132.0
HKD1_k127_245890_8 Thioesterase superfamily K10806 - - 0.0000000000000000000000000003819 124.0
HKD1_k127_245890_9 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000001516 111.0
HKD1_k127_2471634_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 389.0
HKD1_k127_2471634_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000006329 164.0
HKD1_k127_251528_0 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 525.0
HKD1_k127_251528_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001401 282.0
HKD1_k127_251528_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000008814 149.0
HKD1_k127_251528_3 DNA alkylation repair enzyme - - - 0.0006451 50.0
HKD1_k127_2559354_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 1.051e-307 981.0
HKD1_k127_2559354_1 Insulinase (Peptidase family M16) K07263 - - 3.757e-197 627.0
HKD1_k127_2559354_10 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001803 278.0
HKD1_k127_2559354_11 integrase domain protein SAM domain protein K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001929 263.0
HKD1_k127_2559354_12 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001182 249.0
HKD1_k127_2559354_13 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002592 246.0
HKD1_k127_2559354_14 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000003652 187.0
HKD1_k127_2559354_15 DinB family - - - 0.000000000000000000000000000000000000000001908 163.0
HKD1_k127_2559354_16 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000005408 153.0
HKD1_k127_2559354_17 lytic transglycosylase - - - 0.000000000000000000000000000006225 137.0
HKD1_k127_2559354_18 Domain of unknown function (DUF1707) - - - 0.000000000001339 76.0
HKD1_k127_2559354_19 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000006987 71.0
HKD1_k127_2559354_2 GMP synthase C terminal domain K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 579.0
HKD1_k127_2559354_20 response regulator, receiver - - - 0.0000133 58.0
HKD1_k127_2559354_3 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 486.0
HKD1_k127_2559354_4 synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 420.0
HKD1_k127_2559354_5 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 408.0
HKD1_k127_2559354_6 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 393.0
HKD1_k127_2559354_7 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 346.0
HKD1_k127_2559354_8 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 325.0
HKD1_k127_2559354_9 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000697 275.0
HKD1_k127_2589538_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001549 294.0
HKD1_k127_2589538_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000002694 165.0
HKD1_k127_2615140_0 GMC oxidoreductase K03333 - 1.1.3.6 1.638e-229 721.0
HKD1_k127_2615140_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.811e-204 642.0
HKD1_k127_2615140_10 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 308.0
HKD1_k127_2615140_11 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 313.0
HKD1_k127_2615140_12 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005127 310.0
HKD1_k127_2615140_13 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001878 276.0
HKD1_k127_2615140_14 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007173 267.0
HKD1_k127_2615140_15 It is involved in the biological process described with L-phenylalanine catabolic process K00500 GO:0000003,GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0004510,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006464,GO:0006520,GO:0006558,GO:0006559,GO:0006568,GO:0006569,GO:0006570,GO:0006571,GO:0006576,GO:0006582,GO:0006584,GO:0006586,GO:0006725,GO:0006726,GO:0006732,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008150,GO:0008152,GO:0008340,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009073,GO:0009074,GO:0009095,GO:0009308,GO:0009310,GO:0009712,GO:0009713,GO:0009987,GO:0010259,GO:0016053,GO:0016054,GO:0016491,GO:0016597,GO:0016705,GO:0016714,GO:0017144,GO:0018126,GO:0018958,GO:0019438,GO:0019439,GO:0019538,GO:0019748,GO:0019751,GO:0019752,GO:0031406,GO:0032501,GO:0032502,GO:0034311,GO:0034641,GO:0036094,GO:0036211,GO:0040002,GO:0042133,GO:0042136,GO:0042335,GO:0042402,GO:0042423,GO:0042430,GO:0042436,GO:0042438,GO:0042440,GO:0042441,GO:0042558,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043324,GO:0043412,GO:0043436,GO:0043473,GO:0043474,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046146,GO:0046148,GO:0046189,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0048066,GO:0048069,GO:0048856,GO:0050877,GO:0050890,GO:0050896,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901615,GO:1901617,GO:1902221,GO:1902222 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000002015 237.0
HKD1_k127_2615140_16 PFAM NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000002541 229.0
HKD1_k127_2615140_17 ECF sigma factor - - - 0.000000000000000000000000000000000000000000002027 174.0
HKD1_k127_2615140_18 - - - - 0.000000000000000000000000000000000000000005357 176.0
HKD1_k127_2615140_19 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000005137 155.0
HKD1_k127_2615140_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 6.788e-198 638.0
HKD1_k127_2615140_20 Transport permease protein - - - 0.0000000000000000000000000000000001638 153.0
HKD1_k127_2615140_21 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000006397 112.0
HKD1_k127_2615140_22 - - - - 0.000000000000002511 80.0
HKD1_k127_2615140_23 - - - - 0.00000004912 64.0
HKD1_k127_2615140_24 Belongs to the peptidase S8 family - - - 0.00000007156 66.0
HKD1_k127_2615140_3 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 505.0
HKD1_k127_2615140_4 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 491.0
HKD1_k127_2615140_5 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 477.0
HKD1_k127_2615140_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 479.0
HKD1_k127_2615140_7 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 470.0
HKD1_k127_2615140_8 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 365.0
HKD1_k127_2615140_9 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 326.0
HKD1_k127_262831_0 serine-type endopeptidase activity K20276 - - 0.00000000005254 75.0
HKD1_k127_262831_1 polysaccharide deacetylase K15531 - 3.2.1.156 0.00000003375 63.0
HKD1_k127_2635470_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 428.0
HKD1_k127_2661713_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1076.0
HKD1_k127_2661713_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 2.85e-250 786.0
HKD1_k127_2661713_10 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 314.0
HKD1_k127_2661713_11 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 296.0
HKD1_k127_2661713_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 306.0
HKD1_k127_2661713_13 4Fe-4S binding domain K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000783 264.0
HKD1_k127_2661713_14 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000001794 236.0
HKD1_k127_2661713_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001357 220.0
HKD1_k127_2661713_16 - K07112 - - 0.00000000000000000000000000000000000000000000000002303 185.0
HKD1_k127_2661713_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000021 178.0
HKD1_k127_2661713_18 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000003078 160.0
HKD1_k127_2661713_19 DinB family - - - 0.00000000000000000000000000000000000006196 160.0
HKD1_k127_2661713_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 524.0
HKD1_k127_2661713_20 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000008975 136.0
HKD1_k127_2661713_21 Domain of unknown function DUF302 - - - 0.0000000000000000000000000006475 125.0
HKD1_k127_2661713_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000001451 131.0
HKD1_k127_2661713_23 PFAM regulatory protein ArsR - - - 0.000000000000000000001853 98.0
HKD1_k127_2661713_24 membrane - - - 0.000000000000000000004266 107.0
HKD1_k127_2661713_25 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.000000000000000005196 96.0
HKD1_k127_2661713_26 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000105 89.0
HKD1_k127_2661713_27 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000002964 89.0
HKD1_k127_2661713_28 Regulatory protein, FmdB family - - - 0.0000000002262 67.0
HKD1_k127_2661713_29 outer membrane efflux protein - - - 0.00000001569 67.0
HKD1_k127_2661713_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 484.0
HKD1_k127_2661713_30 Conserved TM helix - - - 0.0000001625 61.0
HKD1_k127_2661713_4 chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 457.0
HKD1_k127_2661713_5 PFAM Cys Met metabolism K01760,K01761 - 4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 451.0
HKD1_k127_2661713_6 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 415.0
HKD1_k127_2661713_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 377.0
HKD1_k127_2661713_8 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 360.0
HKD1_k127_2661713_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 353.0
HKD1_k127_2671624_0 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000003183 240.0
HKD1_k127_2671624_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000299 162.0
HKD1_k127_2671624_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000001579 151.0
HKD1_k127_2671624_3 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000000531 85.0
HKD1_k127_2672644_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 415.0
HKD1_k127_2672644_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 337.0
HKD1_k127_2799327_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 507.0
HKD1_k127_2799327_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 415.0
HKD1_k127_2799327_10 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000006375 143.0
HKD1_k127_2799327_11 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000123 106.0
HKD1_k127_2799327_12 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000000005533 101.0
HKD1_k127_2799327_13 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000005612 76.0
HKD1_k127_2799327_14 TGS domain K06944 - - 0.0000000002422 65.0
HKD1_k127_2799327_15 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00006727 56.0
HKD1_k127_2799327_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 370.0
HKD1_k127_2799327_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 374.0
HKD1_k127_2799327_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 360.0
HKD1_k127_2799327_5 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 337.0
HKD1_k127_2799327_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003565 292.0
HKD1_k127_2799327_7 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008255 301.0
HKD1_k127_2799327_8 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000005741 261.0
HKD1_k127_2799327_9 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000002192 226.0
HKD1_k127_2826035_0 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
HKD1_k127_2826035_1 PFAM class II aldolase adducin family protein K01628,K03077 - 4.1.2.17,5.1.3.4 0.0000000000000000000000000000000000000000004996 165.0
HKD1_k127_2826035_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000001661 110.0
HKD1_k127_2865675_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 518.0
HKD1_k127_2865675_1 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 438.0
HKD1_k127_2865675_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000005235 231.0
HKD1_k127_2865675_11 - - - - 0.00000000000000000001095 104.0
HKD1_k127_2865675_12 Helix-turn-helix domain - - - 0.000000000000001271 87.0
HKD1_k127_2865675_13 DnaJ molecular chaperone homology domain - - - 0.000000000008373 74.0
HKD1_k127_2865675_14 - - - - 0.00000004982 63.0
HKD1_k127_2865675_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 411.0
HKD1_k127_2865675_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000008095 287.0
HKD1_k127_2865675_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002223 256.0
HKD1_k127_2865675_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000541 249.0
HKD1_k127_2865675_6 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000001301 237.0
HKD1_k127_2865675_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000003767 242.0
HKD1_k127_2865675_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000003126 246.0
HKD1_k127_2865675_9 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000005144 232.0
HKD1_k127_288322_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1365.0
HKD1_k127_288322_1 Tetratricopeptide TPR_2 repeat protein - - - 2.426e-230 748.0
HKD1_k127_288322_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 333.0
HKD1_k127_288322_11 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 318.0
HKD1_k127_288322_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002011 265.0
HKD1_k127_288322_13 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000002287 203.0
HKD1_k127_288322_14 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000001681 196.0
HKD1_k127_288322_15 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000149 197.0
HKD1_k127_288322_16 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000001966 207.0
HKD1_k127_288322_17 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000001453 195.0
HKD1_k127_288322_18 Helix-turn-helix domain K02806 - - 0.000000000000000000000000000000000000000007773 162.0
HKD1_k127_288322_19 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000001479 148.0
HKD1_k127_288322_2 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 608.0
HKD1_k127_288322_20 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000428 133.0
HKD1_k127_288322_21 STAS domain K04749 - - 0.000000000000000000000000000000005398 138.0
HKD1_k127_288322_22 Histidine kinase - - - 0.0000000000000000000000001447 121.0
HKD1_k127_288322_23 PFAM Cupin superfamily protein K10277,K18055 - 1.14.11.27,1.14.11.30 0.0000000000000000000000008293 119.0
HKD1_k127_288322_24 Zn peptidase - - - 0.00000000000000000000000332 119.0
HKD1_k127_288322_25 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000001299 117.0
HKD1_k127_288322_26 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000001709 111.0
HKD1_k127_288322_27 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000005884 109.0
HKD1_k127_288322_28 helix_turn_helix, mercury resistance - - - 0.00000000000000000001803 97.0
HKD1_k127_288322_29 Forkhead associated domain K01990,K21397 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000002488 94.0
HKD1_k127_288322_3 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 612.0
HKD1_k127_288322_30 DNA-binding protein PTS system, IIA component K02806 - - 0.000000000000003391 85.0
HKD1_k127_288322_31 amine dehydrogenase activity - - - 0.0000000000005733 82.0
HKD1_k127_288322_33 - - - - 0.0006184 53.0
HKD1_k127_288322_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 624.0
HKD1_k127_288322_5 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 533.0
HKD1_k127_288322_6 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 503.0
HKD1_k127_288322_7 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 508.0
HKD1_k127_288322_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 363.0
HKD1_k127_288322_9 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 343.0
HKD1_k127_296741_0 Methyltransferase domain - - - 0.000000000000000002803 91.0
HKD1_k127_299443_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 9.535e-261 834.0
HKD1_k127_299443_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 463.0
HKD1_k127_299443_2 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000005034 100.0
HKD1_k127_3033923_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 522.0
HKD1_k127_3033923_1 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 407.0
HKD1_k127_3033923_2 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 349.0
HKD1_k127_3033923_3 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000001637 210.0
HKD1_k127_3033923_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000001963 182.0
HKD1_k127_3033923_5 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000001139 159.0
HKD1_k127_3033923_6 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000002623 134.0
HKD1_k127_3033923_7 PFAM beta-lactamase domain protein K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.0000000001244 62.0
HKD1_k127_3033923_9 Psort location CytoplasmicMembrane, score 10.00 K09808 - - 0.00000001839 66.0
HKD1_k127_3055156_0 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 3.873e-223 709.0
HKD1_k127_3055156_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 9.025e-203 652.0
HKD1_k127_3055156_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 338.0
HKD1_k127_3055156_11 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 288.0
HKD1_k127_3055156_12 amino acid K03294,K13868 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002594 281.0
HKD1_k127_3055156_13 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002423 274.0
HKD1_k127_3055156_14 KH domain K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000001557 263.0
HKD1_k127_3055156_15 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003022 239.0
HKD1_k127_3055156_16 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000005532 225.0
HKD1_k127_3055156_17 Histidine kinase K02484,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000002165 234.0
HKD1_k127_3055156_18 Gtr1/RagA G protein conserved region K06883 - - 0.000000000000000000000000000000000000000000000000000000004549 224.0
HKD1_k127_3055156_19 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000002832 199.0
HKD1_k127_3055156_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 568.0
HKD1_k127_3055156_20 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000002716 190.0
HKD1_k127_3055156_21 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000004263 181.0
HKD1_k127_3055156_22 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000008858 171.0
HKD1_k127_3055156_23 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002188 164.0
HKD1_k127_3055156_24 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000000000001188 163.0
HKD1_k127_3055156_25 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000685 159.0
HKD1_k127_3055156_26 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000007245 147.0
HKD1_k127_3055156_27 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000005325 136.0
HKD1_k127_3055156_28 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.00000000000000000000000002946 123.0
HKD1_k127_3055156_29 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000001356 106.0
HKD1_k127_3055156_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 457.0
HKD1_k127_3055156_30 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000001108 89.0
HKD1_k127_3055156_33 Protein kinase domain K12132 - 2.7.11.1 0.000007716 58.0
HKD1_k127_3055156_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 416.0
HKD1_k127_3055156_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 400.0
HKD1_k127_3055156_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 378.0
HKD1_k127_3055156_7 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 399.0
HKD1_k127_3055156_8 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 356.0
HKD1_k127_3055156_9 Dak2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 351.0
HKD1_k127_3058912_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.978e-228 728.0
HKD1_k127_3058912_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 445.0
HKD1_k127_3058912_10 PFAM Fimbrial assembly family protein K02663 - - 0.0007044 46.0
HKD1_k127_3058912_2 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 451.0
HKD1_k127_3058912_3 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 401.0
HKD1_k127_3058912_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 355.0
HKD1_k127_3058912_5 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 334.0
HKD1_k127_3058912_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005814 285.0
HKD1_k127_3058912_7 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007902 274.0
HKD1_k127_3058912_8 HAD-superfamily hydrolase, subfamily IIB K07026 - 3.1.3.70 0.00000000000000000000000000001198 129.0
HKD1_k127_3058912_9 transmembrane transport - - - 0.0000000000000000009003 102.0
HKD1_k127_3064952_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 377.0
HKD1_k127_3064952_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 335.0
HKD1_k127_3064952_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000007569 205.0
HKD1_k127_3064952_3 NUDIX domain - - - 0.0000000000000000000000000000000000003726 159.0
HKD1_k127_3094214_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 401.0
HKD1_k127_3094214_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 290.0
HKD1_k127_3094214_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000004778 117.0
HKD1_k127_3094214_11 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000008432 100.0
HKD1_k127_3094214_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000151 92.0
HKD1_k127_3094214_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000001592 90.0
HKD1_k127_3094214_14 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002984 86.0
HKD1_k127_3094214_15 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000003326 85.0
HKD1_k127_3094214_16 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000002716 59.0
HKD1_k127_3094214_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
HKD1_k127_3094214_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002431 205.0
HKD1_k127_3094214_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002587 184.0
HKD1_k127_3094214_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000002301 170.0
HKD1_k127_3094214_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000001426 173.0
HKD1_k127_3094214_7 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002518 171.0
HKD1_k127_3094214_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000001646 149.0
HKD1_k127_3094214_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000003326 125.0
HKD1_k127_310249_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.516e-212 673.0
HKD1_k127_310249_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 446.0
HKD1_k127_310249_10 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000004545 142.0
HKD1_k127_310249_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000006362 143.0
HKD1_k127_310249_12 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000001248 143.0
HKD1_k127_310249_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000001725 98.0
HKD1_k127_310249_14 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000002201 98.0
HKD1_k127_310249_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000005662 93.0
HKD1_k127_310249_16 Protein tyrosine kinase - - - 0.00000000002808 64.0
HKD1_k127_310249_17 Sugar (and other) transporter - - - 0.0002242 50.0
HKD1_k127_310249_18 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.000533 53.0
HKD1_k127_310249_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 376.0
HKD1_k127_310249_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 363.0
HKD1_k127_310249_4 Amino acid kinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 342.0
HKD1_k127_310249_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003066 296.0
HKD1_k127_310249_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001974 282.0
HKD1_k127_310249_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000001462 188.0
HKD1_k127_310249_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001256 181.0
HKD1_k127_310249_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000003158 178.0
HKD1_k127_3104638_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 585.0
HKD1_k127_3104638_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 439.0
HKD1_k127_3104638_10 - - - - 0.0000000000000000001776 99.0
HKD1_k127_3104638_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000004193 90.0
HKD1_k127_3104638_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0001351 54.0
HKD1_k127_3104638_2 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006679 287.0
HKD1_k127_3104638_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002617 266.0
HKD1_k127_3104638_4 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000000007604 172.0
HKD1_k127_3104638_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000002475 158.0
HKD1_k127_3104638_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000002679 133.0
HKD1_k127_3104638_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000001844 130.0
HKD1_k127_3104638_8 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000002727 110.0
HKD1_k127_3104638_9 Pas domain - - - 0.000000000000000000002129 102.0
HKD1_k127_312237_0 Multidrug ABC transporter ATP-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 397.0
HKD1_k127_3133142_0 AMP-binding enzyme K01897 - 6.2.1.3 2.223e-198 635.0
HKD1_k127_3133142_1 PFAM Fatty acid desaturase K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 358.0
HKD1_k127_3133142_2 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 336.0
HKD1_k127_3133142_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000001214 183.0
HKD1_k127_3133142_5 Hydrolase CocE NonD family - - - 0.00000000000000000000000007949 116.0
HKD1_k127_3133142_6 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000001784 115.0
HKD1_k127_3133142_7 Transglycosylase associated protein - - - 0.000000000000000002396 96.0
HKD1_k127_3133142_8 - - - - 0.00000000000003619 83.0
HKD1_k127_3133142_9 SdpI/YhfL protein family - - - 0.00000001981 60.0
HKD1_k127_3156081_0 ABC transporter - - - 2.942e-254 793.0
HKD1_k127_3156081_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.842e-212 673.0
HKD1_k127_3156081_10 Peptidase S53 K08677 - - 0.0000000000000000000000000000000000000000000000000000000000000000001248 259.0
HKD1_k127_3156081_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000001435 240.0
HKD1_k127_3156081_12 - - - - 0.00000000000000000000000000000000000000000000000000000000005677 211.0
HKD1_k127_3156081_13 Ribose/Galactose Isomerase - - - 0.00000000000000000000000000000000000000000000000000006142 204.0
HKD1_k127_3156081_14 Response regulator receiver K07667 - - 0.0000000000000000000000000000000000000000000000000004516 208.0
HKD1_k127_3156081_15 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001534 195.0
HKD1_k127_3156081_16 methyltransferase - - - 0.0000000000000000000000000000000001974 153.0
HKD1_k127_3156081_17 Subtilase family - - - 0.000000000000000000000000000000005643 150.0
HKD1_k127_3156081_18 integral membrane protein - - - 0.00000000000000000000000008596 121.0
HKD1_k127_3156081_19 Lipocalin-like domain - - - 0.0000000000000000000003247 103.0
HKD1_k127_3156081_2 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 634.0
HKD1_k127_3156081_20 Membrane - - - 0.000000000000000005195 99.0
HKD1_k127_3156081_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000001358 98.0
HKD1_k127_3156081_22 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000215 85.0
HKD1_k127_3156081_23 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000002708 61.0
HKD1_k127_3156081_25 Endonuclease I - - - 0.0002122 55.0
HKD1_k127_3156081_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 440.0
HKD1_k127_3156081_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 445.0
HKD1_k127_3156081_5 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 375.0
HKD1_k127_3156081_6 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 323.0
HKD1_k127_3156081_7 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 323.0
HKD1_k127_3156081_8 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 293.0
HKD1_k127_3156081_9 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003162 280.0
HKD1_k127_3159756_0 Pro-kumamolisin, activation domain K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 411.0
HKD1_k127_3159756_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 321.0
HKD1_k127_3159756_2 Domain of unknown function (DUF4126) - - - 0.000000000000000000031 98.0
HKD1_k127_3159756_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00001539 57.0
HKD1_k127_320073_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.246e-238 751.0
HKD1_k127_320073_1 PFAM phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003296 302.0
HKD1_k127_320073_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007284 280.0
HKD1_k127_320073_3 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000005292 215.0
HKD1_k127_320073_4 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00001723 55.0
HKD1_k127_3203408_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 275.0
HKD1_k127_3203408_1 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000232 168.0
HKD1_k127_3203408_2 Transcription elongation factor, N-terminal - - - 0.0000000000000000000000000000000001197 155.0
HKD1_k127_3209733_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 9.943e-282 882.0
HKD1_k127_3209733_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 356.0
HKD1_k127_3209733_2 PFAM glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 336.0
HKD1_k127_3209733_3 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000003231 209.0
HKD1_k127_3209733_4 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000003357 183.0
HKD1_k127_3209733_5 Fatty acid desaturase - - - 0.000000004502 70.0
HKD1_k127_3221792_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 552.0
HKD1_k127_3221792_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 527.0
HKD1_k127_3221792_10 membrane protein domain K18481 - - 0.0004854 50.0
HKD1_k127_3221792_2 PFAM sigma-54 factor interaction domain-containing protein K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 431.0
HKD1_k127_3221792_3 PFAM Formiminotransferase K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 339.0
HKD1_k127_3221792_4 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001148 313.0
HKD1_k127_3221792_5 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000007974 226.0
HKD1_k127_3221792_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000003047 205.0
HKD1_k127_3221792_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000002137 144.0
HKD1_k127_3221792_8 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000001819 143.0
HKD1_k127_3221792_9 Belongs to the peptidase S8 family - - - 0.00000000007407 74.0
HKD1_k127_3225747_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 333.0
HKD1_k127_3225747_1 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000005296 114.0
HKD1_k127_3225747_2 ig-like, plexins, transcription factors - - - 0.0000000000000000000001714 114.0
HKD1_k127_3225747_3 Fimbrial assembly protein (PilN) K02663 - - 0.0000003296 57.0
HKD1_k127_3225747_4 Pilus assembly protein, PilP K02665 - - 0.0000219 56.0
HKD1_k127_3225747_5 PKD domain containing protein - - - 0.000131 55.0
HKD1_k127_3263984_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 361.0
HKD1_k127_3263984_1 - - - - 0.000000000000000000000009019 107.0
HKD1_k127_3263984_2 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.000000000000001737 77.0
HKD1_k127_3263984_3 alpha-L-arabinofuranosidase - - - 0.00000000002739 78.0
HKD1_k127_3263984_4 CHRD domain - - - 0.00000000003607 78.0
HKD1_k127_3263984_5 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000009948 65.0
HKD1_k127_3263984_6 general secretion pathway protein - - - 0.000000101 61.0
HKD1_k127_3263984_7 - - - - 0.0001959 44.0
HKD1_k127_328018_0 Amidase - - - 1.067e-276 866.0
HKD1_k127_328018_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.447e-275 856.0
HKD1_k127_328018_10 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000001416 178.0
HKD1_k127_328018_11 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000001818 164.0
HKD1_k127_328018_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000005756 164.0
HKD1_k127_328018_13 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000003411 105.0
HKD1_k127_328018_14 Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000494 106.0
HKD1_k127_328018_15 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000002101 74.0
HKD1_k127_328018_16 Acetyltransferase (GNAT) domain - - - 0.0000018 61.0
HKD1_k127_328018_17 Belongs to the universal stress protein A family - - - 0.00001758 56.0
HKD1_k127_328018_2 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 611.0
HKD1_k127_328018_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 525.0
HKD1_k127_328018_4 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 469.0
HKD1_k127_328018_5 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 355.0
HKD1_k127_328018_6 arsenite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 354.0
HKD1_k127_328018_7 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 359.0
HKD1_k127_328018_8 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000003535 224.0
HKD1_k127_328018_9 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000006947 194.0
HKD1_k127_328250_0 amino acid - - - 3.243e-197 635.0
HKD1_k127_328250_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.292e-194 621.0
HKD1_k127_328250_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 308.0
HKD1_k127_328250_11 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005367 260.0
HKD1_k127_328250_12 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001378 250.0
HKD1_k127_328250_13 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000001354 239.0
HKD1_k127_328250_14 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000004591 235.0
HKD1_k127_328250_15 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000006475 239.0
HKD1_k127_328250_16 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000002214 208.0
HKD1_k127_328250_17 Cytochrome C assembly protein - - - 0.000000000000000000008426 103.0
HKD1_k127_328250_18 Membrane - - - 0.000000000000000001608 102.0
HKD1_k127_328250_19 Peptidase M56, BlaR1 - - - 0.000000000000001074 89.0
HKD1_k127_328250_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 644.0
HKD1_k127_328250_20 Membrane - - - 0.00000000000002561 88.0
HKD1_k127_328250_21 Serine aminopeptidase, S33 - - - 0.0000000000001001 85.0
HKD1_k127_328250_22 - - - - 0.0000000000001869 85.0
HKD1_k127_328250_23 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000004808 80.0
HKD1_k127_328250_24 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 0.0000000003053 72.0
HKD1_k127_328250_25 oxidoreductase activity - - - 0.00000003436 66.0
HKD1_k127_328250_26 Peptidase M56 - - - 0.00000003637 66.0
HKD1_k127_328250_27 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000005954 64.0
HKD1_k127_328250_28 Heat shock protein DnaJ domain protein - - - 0.00004 56.0
HKD1_k127_328250_29 Zn-dependent protease - - - 0.00007712 55.0
HKD1_k127_328250_3 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 437.0
HKD1_k127_328250_4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 439.0
HKD1_k127_328250_5 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 434.0
HKD1_k127_328250_6 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 413.0
HKD1_k127_328250_7 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 406.0
HKD1_k127_328250_8 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 375.0
HKD1_k127_328250_9 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 377.0
HKD1_k127_3306768_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 447.0
HKD1_k127_3306768_1 Belongs to the UPF0102 family K07460 - - 0.000000000000000006675 91.0
HKD1_k127_3306768_2 - - - - 0.000000000000002702 79.0
HKD1_k127_3306886_0 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 429.0
HKD1_k127_3306886_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000001287 121.0
HKD1_k127_3306886_2 CYTH K05873 - 4.6.1.1 0.00000000000000000000000008044 113.0
HKD1_k127_3306886_3 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000000003797 88.0
HKD1_k127_3306886_4 Type II transport protein GspH K08084 - - 0.00006877 53.0
HKD1_k127_3319339_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 518.0
HKD1_k127_3319339_1 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002243 279.0
HKD1_k127_3319339_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000008555 194.0
HKD1_k127_3319339_3 peptidase - - - 0.00000000000000000000000000000000005463 141.0
HKD1_k127_3319339_4 aminopeptidase N - - - 0.000000000000000007708 92.0
HKD1_k127_3319339_5 NAD+ synthase (glutamine-hydrolyzing) activity K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000002588 62.0
HKD1_k127_3323379_0 Sortilin, neurotensin receptor 3, - - - 0.0 1165.0
HKD1_k127_3323379_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 7.038e-256 802.0
HKD1_k127_3323379_10 Uncharacterized protein conserved in bacteria (DUF2135) K09934 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 325.0
HKD1_k127_3323379_11 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 304.0
HKD1_k127_3323379_12 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005755 288.0
HKD1_k127_3323379_13 serine-type D-Ala-D-Ala carboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001361 258.0
HKD1_k127_3323379_14 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000001474 167.0
HKD1_k127_3323379_15 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.000000000000000000000001111 121.0
HKD1_k127_3323379_16 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000005553 106.0
HKD1_k127_3323379_17 ThiS family - - - 0.000000000000000000004732 109.0
HKD1_k127_3323379_18 nuclear chromosome segregation - - - 0.0000000000000000000232 102.0
HKD1_k127_3323379_19 Protein of unknown function (DUF1175) K09934 - - 0.00000000000000000003534 105.0
HKD1_k127_3323379_2 Alpha-2-Macroglobulin K06894 - - 8.79e-219 748.0
HKD1_k127_3323379_20 domain, Protein K12685,K16785,K16786,K16787 - - 0.000000000000005273 87.0
HKD1_k127_3323379_21 acyl carrier protein - - - 0.00000000002378 66.0
HKD1_k127_3323379_22 - - - - 0.000000004775 68.0
HKD1_k127_3323379_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 1.084e-202 645.0
HKD1_k127_3323379_4 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 3.569e-198 632.0
HKD1_k127_3323379_5 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 579.0
HKD1_k127_3323379_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 543.0
HKD1_k127_3323379_7 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 551.0
HKD1_k127_3323379_8 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 457.0
HKD1_k127_3323379_9 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 416.0
HKD1_k127_3325863_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 625.0
HKD1_k127_3325863_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 427.0
HKD1_k127_3325863_10 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 300.0
HKD1_k127_3325863_11 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007351 276.0
HKD1_k127_3325863_12 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001553 259.0
HKD1_k127_3325863_13 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000251 260.0
HKD1_k127_3325863_14 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000007255 258.0
HKD1_k127_3325863_15 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000192 220.0
HKD1_k127_3325863_16 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000002496 198.0
HKD1_k127_3325863_17 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000002713 215.0
HKD1_k127_3325863_18 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000005141 186.0
HKD1_k127_3325863_19 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000002368 179.0
HKD1_k127_3325863_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 395.0
HKD1_k127_3325863_20 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000009971 157.0
HKD1_k127_3325863_21 - - - - 0.00000000000000002511 92.0
HKD1_k127_3325863_22 TPR repeat - - - 0.0000000000002859 83.0
HKD1_k127_3325863_23 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.00006763 47.0
HKD1_k127_3325863_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 384.0
HKD1_k127_3325863_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 378.0
HKD1_k127_3325863_5 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 372.0
HKD1_k127_3325863_6 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 359.0
HKD1_k127_3325863_7 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 323.0
HKD1_k127_3325863_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 308.0
HKD1_k127_3325863_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 299.0
HKD1_k127_3339447_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 1.098e-206 651.0
HKD1_k127_3339447_1 PFAM type II secretion system K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 454.0
HKD1_k127_3339447_10 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 326.0
HKD1_k127_3339447_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 305.0
HKD1_k127_3339447_12 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001082 287.0
HKD1_k127_3339447_13 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001922 250.0
HKD1_k127_3339447_14 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000006079 255.0
HKD1_k127_3339447_15 MoeA N-terminal region (domain I and II) K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000001066 242.0
HKD1_k127_3339447_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000005684 246.0
HKD1_k127_3339447_17 Two component regulator propeller - - - 0.00000000000000000000000000000000000002396 164.0
HKD1_k127_3339447_18 DinB superfamily - - - 0.000000000000000000000001038 117.0
HKD1_k127_3339447_19 phosphorelay signal transduction system - - - 0.000000000000000000000001346 113.0
HKD1_k127_3339447_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 452.0
HKD1_k127_3339447_20 - - - - 0.00000000000000000000008541 115.0
HKD1_k127_3339447_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000001092 103.0
HKD1_k127_3339447_22 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000004781 98.0
HKD1_k127_3339447_24 Regulatory protein, FmdB - - - 0.00000000000000001554 95.0
HKD1_k127_3339447_25 - - - - 0.0000000000004823 83.0
HKD1_k127_3339447_26 Uncharacterized ACR, COG1430 K09005 - - 0.000000000001155 81.0
HKD1_k127_3339447_27 - - - - 0.000007375 60.0
HKD1_k127_3339447_3 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 424.0
HKD1_k127_3339447_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 414.0
HKD1_k127_3339447_5 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 357.0
HKD1_k127_3339447_6 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 343.0
HKD1_k127_3339447_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 332.0
HKD1_k127_3339447_8 Microcin C7 resistance K01297 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 323.0
HKD1_k127_3339447_9 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 335.0
HKD1_k127_3344439_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1137.0
HKD1_k127_3344439_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1071.0
HKD1_k127_3344439_10 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 331.0
HKD1_k127_3344439_11 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 299.0
HKD1_k127_3344439_12 CHASE3 domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 312.0
HKD1_k127_3344439_13 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000655 244.0
HKD1_k127_3344439_14 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000319 216.0
HKD1_k127_3344439_15 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000001629 205.0
HKD1_k127_3344439_16 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000007671 137.0
HKD1_k127_3344439_17 amine dehydrogenase activity - - - 0.00000000000000000000005829 113.0
HKD1_k127_3344439_18 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000645 106.0
HKD1_k127_3344439_2 secondary active sulfate transmembrane transporter activity K03321 - - 8.914e-281 873.0
HKD1_k127_3344439_3 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.831e-243 780.0
HKD1_k127_3344439_4 Involved in the tonB-independent uptake of proteins - - - 4.226e-228 735.0
HKD1_k127_3344439_5 radical SAM domain protein - - - 1.444e-216 684.0
HKD1_k127_3344439_6 Isocitrate/isopropylmalate dehydrogenase - - - 1.26e-197 619.0
HKD1_k127_3344439_7 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 593.0
HKD1_k127_3344439_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 400.0
HKD1_k127_3344439_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 394.0
HKD1_k127_3357868_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 340.0
HKD1_k127_3357868_1 Bacterial PH domain - - - 0.0000000000001846 80.0
HKD1_k127_3384211_0 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 314.0
HKD1_k127_3384211_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000008737 262.0
HKD1_k127_3384211_2 Protein of unknown function (DUF4243) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002183 264.0
HKD1_k127_3384211_3 - - - - 0.0000000000000000000001517 99.0
HKD1_k127_3384211_4 - - - - 0.000000000000003582 79.0
HKD1_k127_3392792_0 - - - - 2.971e-318 983.0
HKD1_k127_3392792_1 Prolyl oligopeptidase K01322 - 3.4.21.26 6.834e-235 746.0
HKD1_k127_3392792_2 Involved in the tonB-independent uptake of proteins - - - 7.543e-203 661.0
HKD1_k127_3392792_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004918 249.0
HKD1_k127_3392792_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000006249 157.0
HKD1_k127_3405692_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 3.339e-305 954.0
HKD1_k127_3405692_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.254e-252 789.0
HKD1_k127_3405692_10 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 369.0
HKD1_k127_3405692_11 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 325.0
HKD1_k127_3405692_12 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 311.0
HKD1_k127_3405692_13 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004953 291.0
HKD1_k127_3405692_14 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000001284 218.0
HKD1_k127_3405692_15 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000001158 190.0
HKD1_k127_3405692_16 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000455 150.0
HKD1_k127_3405692_17 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000005363 155.0
HKD1_k127_3405692_18 AAA domain - - - 0.000000000000000000000000000000000142 152.0
HKD1_k127_3405692_19 EamA-like transporter family - - - 0.0000000000000000000000000000002633 136.0
HKD1_k127_3405692_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 584.0
HKD1_k127_3405692_20 Rhodanese Homology Domain - - - 0.00000000000000000000005998 102.0
HKD1_k127_3405692_21 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000005531 89.0
HKD1_k127_3405692_22 VanZ like family - - - 0.00000000005865 77.0
HKD1_k127_3405692_23 transcriptional regulator - - - 0.0000001201 61.0
HKD1_k127_3405692_3 serine-type peptidase activity K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 615.0
HKD1_k127_3405692_4 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 429.0
HKD1_k127_3405692_5 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 411.0
HKD1_k127_3405692_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 420.0
HKD1_k127_3405692_7 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 414.0
HKD1_k127_3405692_8 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 372.0
HKD1_k127_3405692_9 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 375.0
HKD1_k127_3416256_1 Protein of unknown function K09800 - - 0.00000000000000000000000000000000000000000000000000002259 209.0
HKD1_k127_347747_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 463.0
HKD1_k127_347747_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 408.0
HKD1_k127_347747_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000007925 98.0
HKD1_k127_347747_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000001042 77.0
HKD1_k127_347747_12 Asparagine synthase K01953 - 6.3.5.4 0.000000001071 61.0
HKD1_k127_347747_2 Pyridoxal-phosphate dependent enzyme K01738,K17216 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 359.0
HKD1_k127_347747_3 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002059 263.0
HKD1_k127_347747_4 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001017 228.0
HKD1_k127_347747_5 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000004568 211.0
HKD1_k127_347747_6 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000007613 154.0
HKD1_k127_347747_7 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000008809 128.0
HKD1_k127_347747_8 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000001526 130.0
HKD1_k127_347747_9 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000001015 103.0
HKD1_k127_348529_0 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000000000006279 169.0
HKD1_k127_348529_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000001124 166.0
HKD1_k127_348529_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000002508 161.0
HKD1_k127_348529_3 PFAM von Willebrand factor type A K07114,K12511 - - 0.00000000000000000001375 104.0
HKD1_k127_348529_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000001167 90.0
HKD1_k127_348529_5 Plasmid stability protein K21495 - - 0.000000002931 63.0
HKD1_k127_351820_0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 291.0
HKD1_k127_351820_1 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000184 175.0
HKD1_k127_351820_2 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K12941 - - 0.000000000000000000000000000000000000003019 155.0
HKD1_k127_351820_3 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000004185 132.0
HKD1_k127_3520108_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 291.0
HKD1_k127_3520108_1 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002898 248.0
HKD1_k127_3520108_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000003003 221.0
HKD1_k127_3520108_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000008497 168.0
HKD1_k127_3552584_0 Involved in the tonB-independent uptake of proteins - - - 2.268e-195 638.0
HKD1_k127_3552584_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 429.0
HKD1_k127_3552584_10 (FHA) domain - - - 0.000000000198 71.0
HKD1_k127_3552584_11 positive regulation of growth - - - 0.00006518 54.0
HKD1_k127_3552584_2 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 384.0
HKD1_k127_3552584_3 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 394.0
HKD1_k127_3552584_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
HKD1_k127_3552584_5 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000004907 195.0
HKD1_k127_3552584_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000001437 189.0
HKD1_k127_3552584_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000001655 142.0
HKD1_k127_3552584_8 PIN domain K07064 - - 0.00000000000002488 79.0
HKD1_k127_3552584_9 Adenylate cyclase - - - 0.00000000001888 74.0
HKD1_k127_3581663_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 287.0
HKD1_k127_3581663_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000001212 198.0
HKD1_k127_3581663_2 Sporulation related domain - - - 0.00001215 53.0
HKD1_k127_3591037_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 7.676e-198 627.0
HKD1_k127_3591037_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 535.0
HKD1_k127_3591037_2 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001023 266.0
HKD1_k127_3591037_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001576 247.0
HKD1_k127_3591037_4 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000002559 237.0
HKD1_k127_3591037_5 DinB family - - - 0.00000000000000000000000000000000005507 139.0
HKD1_k127_3591037_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000929 94.0
HKD1_k127_3618808_0 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 359.0
HKD1_k127_3618808_1 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000002098 146.0
HKD1_k127_3618808_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000006139 143.0
HKD1_k127_3618808_3 EamA-like transporter family - - - 0.0000000000000000000000000003676 126.0
HKD1_k127_3618808_4 antibiotic catabolic process - - - 0.0000000001615 76.0
HKD1_k127_3618808_5 - - - - 0.00005511 53.0
HKD1_k127_3756679_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 522.0
HKD1_k127_3756679_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 397.0
HKD1_k127_3756679_10 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000126 147.0
HKD1_k127_3756679_11 AI-2E family transporter - - - 0.0000000000000000000000000000000001837 147.0
HKD1_k127_3756679_12 phosphorelay signal transduction system - - - 0.000000000000000000000000003065 122.0
HKD1_k127_3756679_13 Periplasmic binding protein K02016 - - 0.00000000000000000000000004654 126.0
HKD1_k127_3756679_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000003688 109.0
HKD1_k127_3756679_15 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.000000000000000000002716 109.0
HKD1_k127_3756679_16 FAD linked K00104 - 1.1.3.15 0.000000000000001287 77.0
HKD1_k127_3756679_18 chlorophyll binding - - - 0.0001846 54.0
HKD1_k127_3756679_2 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
HKD1_k127_3756679_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 346.0
HKD1_k127_3756679_4 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 299.0
HKD1_k127_3756679_5 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000001463 244.0
HKD1_k127_3756679_6 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000004471 239.0
HKD1_k127_3756679_7 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000001432 244.0
HKD1_k127_3756679_8 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000004049 218.0
HKD1_k127_3756679_9 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000217 195.0
HKD1_k127_384570_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 491.0
HKD1_k127_384570_1 Glycyl-tRNA synthetase beta subunit K01879,K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 481.0
HKD1_k127_384570_2 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 313.0
HKD1_k127_384570_3 FR47-like protein - - - 0.000000000000000000000000000000000298 152.0
HKD1_k127_399203_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 514.0
HKD1_k127_399203_1 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 391.0
HKD1_k127_399203_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000002403 171.0
HKD1_k127_399203_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000001186 179.0
HKD1_k127_399203_4 histone H2A K63-linked ubiquitination K10914 - - 0.000000000000000000000000000000000001798 151.0
HKD1_k127_399203_6 YacP-like NYN domain - - - 0.0000007958 57.0
HKD1_k127_4042572_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 608.0
HKD1_k127_4042572_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.00000000000000000000000000000000000000000009265 163.0
HKD1_k127_4042572_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 0.000000000000007947 74.0
HKD1_k127_40625_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 8.864e-226 732.0
HKD1_k127_40625_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 604.0
HKD1_k127_40625_2 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000001075 177.0
HKD1_k127_40625_3 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000001023 129.0
HKD1_k127_40625_4 TIGRFAM MJ0042 family finger-like protein - - - 0.000000006317 64.0
HKD1_k127_40625_5 - - - - 0.00000003364 67.0
HKD1_k127_40625_6 Protein of unknown function (DUF2752) - - - 0.0000008985 60.0
HKD1_k127_4167338_0 PFAM Type II secretion system protein E K02652 - - 5.318e-209 682.0
HKD1_k127_4167338_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000121 295.0
HKD1_k127_4167338_2 PFAM Fimbrial assembly family protein K02663 - - 0.0007768 49.0
HKD1_k127_4190376_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.779e-301 937.0
HKD1_k127_4190376_1 Prolyl oligopeptidase family - - - 1.05e-256 817.0
HKD1_k127_4190376_10 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 471.0
HKD1_k127_4190376_11 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 461.0
HKD1_k127_4190376_12 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 459.0
HKD1_k127_4190376_13 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 427.0
HKD1_k127_4190376_14 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 422.0
HKD1_k127_4190376_15 Aminotransferase, class I II K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 410.0
HKD1_k127_4190376_16 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 389.0
HKD1_k127_4190376_17 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 389.0
HKD1_k127_4190376_18 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 374.0
HKD1_k127_4190376_19 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 378.0
HKD1_k127_4190376_2 Sugar (and other) transporter - - - 1.326e-243 762.0
HKD1_k127_4190376_20 PFAM Major facilitator superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 347.0
HKD1_k127_4190376_21 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 338.0
HKD1_k127_4190376_22 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 334.0
HKD1_k127_4190376_23 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
HKD1_k127_4190376_24 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 343.0
HKD1_k127_4190376_25 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 329.0
HKD1_k127_4190376_26 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 305.0
HKD1_k127_4190376_27 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 326.0
HKD1_k127_4190376_28 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 331.0
HKD1_k127_4190376_29 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 313.0
HKD1_k127_4190376_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.021e-234 759.0
HKD1_k127_4190376_30 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002614 298.0
HKD1_k127_4190376_31 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003661 284.0
HKD1_k127_4190376_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001083 274.0
HKD1_k127_4190376_33 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005124 275.0
HKD1_k127_4190376_34 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002633 301.0
HKD1_k127_4190376_35 Abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003689 279.0
HKD1_k127_4190376_36 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005113 263.0
HKD1_k127_4190376_37 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001764 252.0
HKD1_k127_4190376_38 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008875 244.0
HKD1_k127_4190376_39 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000001809 266.0
HKD1_k127_4190376_4 Belongs to the aldehyde dehydrogenase family K22187 - - 7.952e-221 695.0
HKD1_k127_4190376_40 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000008958 242.0
HKD1_k127_4190376_41 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000001152 242.0
HKD1_k127_4190376_42 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000006882 253.0
HKD1_k127_4190376_43 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000001279 252.0
HKD1_k127_4190376_44 L-phenylalanine transmembrane transporter activity K01998 - - 0.0000000000000000000000000000000000000000000000000000000000001005 236.0
HKD1_k127_4190376_45 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000004023 218.0
HKD1_k127_4190376_46 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000002769 232.0
HKD1_k127_4190376_47 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000001195 213.0
HKD1_k127_4190376_48 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000004832 229.0
HKD1_k127_4190376_49 transport system permease K01998 - - 0.000000000000000000000000000000000000000000000000000000806 216.0
HKD1_k127_4190376_5 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 548.0
HKD1_k127_4190376_50 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000002552 199.0
HKD1_k127_4190376_51 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000001092 197.0
HKD1_k127_4190376_52 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000005787 190.0
HKD1_k127_4190376_53 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000003835 184.0
HKD1_k127_4190376_54 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000005707 179.0
HKD1_k127_4190376_55 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000008549 186.0
HKD1_k127_4190376_56 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000006677 169.0
HKD1_k127_4190376_57 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000111 156.0
HKD1_k127_4190376_58 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000009417 139.0
HKD1_k127_4190376_59 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000005468 133.0
HKD1_k127_4190376_6 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 511.0
HKD1_k127_4190376_60 diguanylate cyclase - - - 0.00000000000000000000000000000000593 140.0
HKD1_k127_4190376_61 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000007401 146.0
HKD1_k127_4190376_62 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000001383 132.0
HKD1_k127_4190376_63 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000004604 134.0
HKD1_k127_4190376_64 Hydrogenase maturation protease - - - 0.000000000000000000000000001492 129.0
HKD1_k127_4190376_65 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000004762 115.0
HKD1_k127_4190376_66 Polymer-forming cytoskeletal - - - 0.000000000000000002052 100.0
HKD1_k127_4190376_67 AMMECR1 K09141 - - 0.0000000000000002815 89.0
HKD1_k127_4190376_68 - - - - 0.0000000000004297 78.0
HKD1_k127_4190376_69 Phosphate-selective porin O and P - - - 0.000000000002546 79.0
HKD1_k127_4190376_7 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 490.0
HKD1_k127_4190376_71 Transglutaminase/protease-like homologues - - - 0.000000002808 69.0
HKD1_k127_4190376_72 Lipocalin-like domain - - - 0.0000002755 59.0
HKD1_k127_4190376_73 OST-HTH/LOTUS domain - - - 0.00000065 51.0
HKD1_k127_4190376_8 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 492.0
HKD1_k127_4190376_9 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 477.0
HKD1_k127_4256785_0 Beta-lactamase - - - 3.261e-222 710.0
HKD1_k127_4256785_1 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 4.611e-206 676.0
HKD1_k127_4256785_10 anaphase-promoting complex binding K20332 - - 0.000000000000000000000000000000000000000000000000000000000004468 216.0
HKD1_k127_4256785_11 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000005635 207.0
HKD1_k127_4256785_12 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
HKD1_k127_4256785_13 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000002248 200.0
HKD1_k127_4256785_14 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000000000004939 170.0
HKD1_k127_4256785_15 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000002386 157.0
HKD1_k127_4256785_16 Cupin - - - 0.00000000000000000000000000000289 124.0
HKD1_k127_4256785_17 Methyltransferase domain - - - 0.0000000000000000000000000006175 123.0
HKD1_k127_4256785_19 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000002248 119.0
HKD1_k127_4256785_2 transcription factor binding K02584 - - 2.577e-195 621.0
HKD1_k127_4256785_20 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000004756 119.0
HKD1_k127_4256785_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 596.0
HKD1_k127_4256785_4 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 569.0
HKD1_k127_4256785_5 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 544.0
HKD1_k127_4256785_6 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 419.0
HKD1_k127_4256785_7 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 412.0
HKD1_k127_4256785_8 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 351.0
HKD1_k127_4256785_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 355.0
HKD1_k127_4260256_0 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 358.0
HKD1_k127_4260256_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000009344 129.0
HKD1_k127_4260256_2 Belongs to the peptidase S8 family - - - 0.00000000000001351 79.0
HKD1_k127_4260256_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000001451 79.0
HKD1_k127_4260256_4 Belongs to the peptidase S8 family - - - 0.000000000004938 72.0
HKD1_k127_4260256_5 polysaccharide deacetylase K15531 - 3.2.1.156 0.00000000003471 78.0
HKD1_k127_4260256_6 peptidyl-tyrosine sulfation - - - 0.000002846 60.0
HKD1_k127_4261111_0 Protein kinase domain K12132 - 2.7.11.1 7.927e-235 757.0
HKD1_k127_4261111_1 Involved in the tonB-independent uptake of proteins - - - 2.981e-218 704.0
HKD1_k127_4261111_10 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 361.0
HKD1_k127_4261111_11 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 318.0
HKD1_k127_4261111_12 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000002382 275.0
HKD1_k127_4261111_13 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000005963 255.0
HKD1_k127_4261111_14 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002291 248.0
HKD1_k127_4261111_15 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000002228 226.0
HKD1_k127_4261111_16 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000009139 166.0
HKD1_k127_4261111_17 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000005377 163.0
HKD1_k127_4261111_18 Cytochrome c - - - 0.000000000000000000000000000000000000709 156.0
HKD1_k127_4261111_19 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000004321 120.0
HKD1_k127_4261111_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 6.842e-218 707.0
HKD1_k127_4261111_20 Cytochrome c - - - 0.000000000000000000004648 107.0
HKD1_k127_4261111_21 nitric oxide dioxygenase activity - - - 0.0000000000000000002532 104.0
HKD1_k127_4261111_22 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000002426 76.0
HKD1_k127_4261111_3 Protein kinase domain K12132 - 2.7.11.1 5.038e-213 702.0
HKD1_k127_4261111_4 Involved in the tonB-independent uptake of proteins - - - 1.934e-204 668.0
HKD1_k127_4261111_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 9.118e-195 640.0
HKD1_k127_4261111_6 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 628.0
HKD1_k127_4261111_7 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 627.0
HKD1_k127_4261111_8 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 431.0
HKD1_k127_4261111_9 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 436.0
HKD1_k127_4265849_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907,K01908 - 6.2.1.1,6.2.1.16,6.2.1.17 0.0 1102.0
HKD1_k127_4265849_1 Protein of unknown function (DUF3604) - - - 0.0 1058.0
HKD1_k127_4265849_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 - 4.1.99.22,4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 265.0
HKD1_k127_4265849_11 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000005189 277.0
HKD1_k127_4265849_12 Surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000000007282 263.0
HKD1_k127_4265849_13 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000001961 248.0
HKD1_k127_4265849_14 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000001206 240.0
HKD1_k127_4265849_15 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000001165 203.0
HKD1_k127_4265849_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000652 189.0
HKD1_k127_4265849_17 protein secretion K09800 - - 0.000000000000000000000000000000000000003404 170.0
HKD1_k127_4265849_18 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000003432 153.0
HKD1_k127_4265849_19 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000002322 165.0
HKD1_k127_4265849_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 522.0
HKD1_k127_4265849_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000004432 140.0
HKD1_k127_4265849_22 glycosyl transferase - - - 0.000000000000000000000000009287 122.0
HKD1_k127_4265849_23 YMGG-like Gly-zipper - - - 0.00000000000000000002661 108.0
HKD1_k127_4265849_24 - - - - 0.000000000000000002611 102.0
HKD1_k127_4265849_25 COG0517 FOG CBS domain - - - 0.000000000000000002973 92.0
HKD1_k127_4265849_26 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000009905 95.0
HKD1_k127_4265849_28 PFAM PKD domain containing protein - - - 0.000000002116 72.0
HKD1_k127_4265849_29 lipolytic protein G-D-S-L family - - - 0.0000005457 61.0
HKD1_k127_4265849_3 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 494.0
HKD1_k127_4265849_30 SMART Tetratricopeptide domain protein - - - 0.00007714 53.0
HKD1_k127_4265849_4 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 460.0
HKD1_k127_4265849_5 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 434.0
HKD1_k127_4265849_6 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 381.0
HKD1_k127_4265849_7 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 354.0
HKD1_k127_4265849_8 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 351.0
HKD1_k127_4265849_9 Domain of unknown function (DUF4331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002188 290.0
HKD1_k127_428633_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 436.0
HKD1_k127_428633_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 390.0
HKD1_k127_428633_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 408.0
HKD1_k127_428633_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 340.0
HKD1_k127_428633_4 peptidase K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000006736 278.0
HKD1_k127_428633_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000683 223.0
HKD1_k127_428633_6 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000005291 170.0
HKD1_k127_428633_7 Binds the 23S rRNA K02909 - - 0.00000000000000000000001833 117.0
HKD1_k127_428633_8 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000004869 102.0
HKD1_k127_428633_9 - - - - 0.0000000000185 76.0
HKD1_k127_4291232_0 Carboxypeptidase regulatory-like domain - - - 2.219e-233 756.0
HKD1_k127_4291232_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 567.0
HKD1_k127_4291232_10 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000002441 205.0
HKD1_k127_4291232_11 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000177 175.0
HKD1_k127_4291232_12 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000004161 155.0
HKD1_k127_4291232_13 DEAD DEAH box helicase K03724 - - 0.00000000000000000003811 102.0
HKD1_k127_4291232_14 - - - - 0.000001187 58.0
HKD1_k127_4291232_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 476.0
HKD1_k127_4291232_3 Amino acid permease K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 380.0
HKD1_k127_4291232_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 355.0
HKD1_k127_4291232_5 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 293.0
HKD1_k127_4291232_6 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003682 293.0
HKD1_k127_4291232_7 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009544 267.0
HKD1_k127_4291232_8 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000001674 248.0
HKD1_k127_4291232_9 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000002876 206.0
HKD1_k127_4294352_0 - - - - 1.86e-234 791.0
HKD1_k127_4294352_1 Oligopeptide transporter OPT - - - 1.255e-228 731.0
HKD1_k127_4294352_10 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 375.0
HKD1_k127_4294352_11 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 355.0
HKD1_k127_4294352_12 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 342.0
HKD1_k127_4294352_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 325.0
HKD1_k127_4294352_14 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 303.0
HKD1_k127_4294352_15 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004862 302.0
HKD1_k127_4294352_16 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001671 273.0
HKD1_k127_4294352_17 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000001155 284.0
HKD1_k127_4294352_18 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HKD1_k127_4294352_19 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001871 260.0
HKD1_k127_4294352_2 intracellular protein transport K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 523.0
HKD1_k127_4294352_20 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000003388 245.0
HKD1_k127_4294352_21 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000001921 213.0
HKD1_k127_4294352_23 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000001623 206.0
HKD1_k127_4294352_24 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000001385 203.0
HKD1_k127_4294352_25 AAA domain - - - 0.000000000000000000000000000000000000000000000000000001717 199.0
HKD1_k127_4294352_26 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000001096 213.0
HKD1_k127_4294352_27 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000007459 211.0
HKD1_k127_4294352_28 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000005598 166.0
HKD1_k127_4294352_29 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000001955 158.0
HKD1_k127_4294352_3 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 476.0
HKD1_k127_4294352_30 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000006391 145.0
HKD1_k127_4294352_31 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000687 149.0
HKD1_k127_4294352_32 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000007372 154.0
HKD1_k127_4294352_33 phosphatase activity K07025 - - 0.00000000000000000000000000000003681 134.0
HKD1_k127_4294352_34 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.000000000000000000000000001568 115.0
HKD1_k127_4294352_35 TonB C terminal K03832 - - 0.000000000000000000000000005049 115.0
HKD1_k127_4294352_36 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000002297 121.0
HKD1_k127_4294352_38 DinB superfamily - - - 0.000000000000000003883 97.0
HKD1_k127_4294352_39 DinB superfamily - - - 0.000000000000002284 88.0
HKD1_k127_4294352_4 surface antigen variable number repeat protein K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 489.0
HKD1_k127_4294352_40 Protein of unknown function (DUF2752) - - - 0.0000000000001477 76.0
HKD1_k127_4294352_41 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000005505 70.0
HKD1_k127_4294352_42 WD40-like Beta Propeller Repeat - - - 0.000000003072 72.0
HKD1_k127_4294352_43 - - - - 0.00000005589 60.0
HKD1_k127_4294352_44 Serine hydrolase (FSH1) - - - 0.0000009048 63.0
HKD1_k127_4294352_45 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00003529 49.0
HKD1_k127_4294352_46 Aminotransferase class-V K04487 - 2.8.1.7 0.0001757 51.0
HKD1_k127_4294352_48 - - - - 0.0008529 50.0
HKD1_k127_4294352_5 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 462.0
HKD1_k127_4294352_6 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 448.0
HKD1_k127_4294352_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 460.0
HKD1_k127_4294352_8 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 434.0
HKD1_k127_4294352_9 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 392.0
HKD1_k127_4300343_0 4Fe-4S single cluster domain K06937 - - 1.256e-247 784.0
HKD1_k127_4300343_1 FAD dependent oxidoreductase - - - 9.644e-212 695.0
HKD1_k127_4300343_10 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.00000000000000001496 98.0
HKD1_k127_4300343_11 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000339 85.0
HKD1_k127_4300343_12 mttA/Hcf106 family K03116 - - 0.0000000000008461 70.0
HKD1_k127_4300343_13 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000797 71.0
HKD1_k127_4300343_14 LysM domain - - - 0.000000001647 68.0
HKD1_k127_4300343_15 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000006478 62.0
HKD1_k127_4300343_16 PFAM helix-turn-helix, Fis-type - - - 0.0000002278 55.0
HKD1_k127_4300343_17 protein domain associated with - - - 0.0001326 51.0
HKD1_k127_4300343_18 TonB-dependent Receptor Plug Domain - - - 0.0005261 46.0
HKD1_k127_4300343_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 479.0
HKD1_k127_4300343_3 Histidine kinase-like ATPases K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 343.0
HKD1_k127_4300343_4 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 303.0
HKD1_k127_4300343_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000003182 230.0
HKD1_k127_4300343_6 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.000000000000000000000000000000000000000008824 167.0
HKD1_k127_4300343_7 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000001679 133.0
HKD1_k127_4300343_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000002631 122.0
HKD1_k127_4300343_9 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000002143 104.0
HKD1_k127_4313732_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 392.0
HKD1_k127_4313732_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 308.0
HKD1_k127_4313732_10 AAA domain - - - 0.0000001566 65.0
HKD1_k127_4313732_11 F plasmid transfer operon, TraF, protein - - - 0.000001539 60.0
HKD1_k127_4313732_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000001761 58.0
HKD1_k127_4313732_13 protein-disulfide reductase activity K01829,K04084 - 1.8.1.8,5.3.4.1 0.00009621 51.0
HKD1_k127_4313732_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002671 284.0
HKD1_k127_4313732_3 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000097 256.0
HKD1_k127_4313732_4 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000005616 120.0
HKD1_k127_4313732_5 Calcineurin-like phosphoesterase K03547 - - 0.0000000000000000000002819 110.0
HKD1_k127_4313732_6 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000002326 92.0
HKD1_k127_4313732_7 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000002762 89.0
HKD1_k127_4313732_8 Protein of unknown function (FYDLN_acid) - - - 0.000000000004009 75.0
HKD1_k127_4313732_9 Tetratricopeptide repeat - - - 0.00000005837 63.0
HKD1_k127_4330138_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.958e-227 734.0
HKD1_k127_4330138_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 493.0
HKD1_k127_4330138_10 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000007668 235.0
HKD1_k127_4330138_11 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000000000000000000000009405 197.0
HKD1_k127_4330138_12 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000000002219 196.0
HKD1_k127_4330138_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000001048 188.0
HKD1_k127_4330138_14 TIGRFAM phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000001515 190.0
HKD1_k127_4330138_15 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000006067 99.0
HKD1_k127_4330138_16 symporter activity K03307 - - 0.00000000000000006798 94.0
HKD1_k127_4330138_17 Fibronectin type 3 domain - - - 0.0000000000000001095 92.0
HKD1_k127_4330138_18 Protein of unknown function (DUF1573) - - - 0.00000000000006089 86.0
HKD1_k127_4330138_19 Bacterial regulatory proteins, tetR family - - - 0.00000000000131 75.0
HKD1_k127_4330138_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 440.0
HKD1_k127_4330138_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000002186 63.0
HKD1_k127_4330138_22 ubiE/COQ5 methyltransferase family - - - 0.0000002264 61.0
HKD1_k127_4330138_23 methyltransferase K15942 - 2.1.1.288 0.00000309 60.0
HKD1_k127_4330138_24 Acetyltransferase (GNAT) domain - - - 0.000007704 57.0
HKD1_k127_4330138_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001317 57.0
HKD1_k127_4330138_3 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 377.0
HKD1_k127_4330138_4 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 363.0
HKD1_k127_4330138_5 Peptidase, M20 K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 317.0
HKD1_k127_4330138_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 305.0
HKD1_k127_4330138_7 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005893 256.0
HKD1_k127_4330138_8 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000002861 252.0
HKD1_k127_4330138_9 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000768 241.0
HKD1_k127_4332893_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1048.0
HKD1_k127_4332893_1 OPT oligopeptide transporter protein - - - 2.221e-301 937.0
HKD1_k127_4332893_10 - - - - 0.00000000000000000000000008949 120.0
HKD1_k127_4332893_11 Protein of unknown function (DUF3175) - - - 0.000000000000000002679 87.0
HKD1_k127_4332893_12 Sensors of blue-light using FAD - - - 0.000000000000001079 84.0
HKD1_k127_4332893_2 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 616.0
HKD1_k127_4332893_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 604.0
HKD1_k127_4332893_4 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 544.0
HKD1_k127_4332893_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000006224 249.0
HKD1_k127_4332893_6 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000001226 206.0
HKD1_k127_4332893_7 acetyltransferase K19113 - - 0.000000000000000000000000000000000000000000000001431 179.0
HKD1_k127_4332893_8 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000001178 173.0
HKD1_k127_4332893_9 signal-transduction protein containing cAMP-binding and CBS domains K00031,K02342,K07182,K14446 - 1.1.1.42,1.3.1.85,2.7.7.7 0.00000000000000000000000004059 115.0
HKD1_k127_434038_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001994 277.0
HKD1_k127_434038_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000007407 231.0
HKD1_k127_434038_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000001247 113.0
HKD1_k127_434038_3 ribonuclease BN K07058 - - 0.00001534 57.0
HKD1_k127_434038_4 Bacterial regulatory proteins, tetR family K09017 - - 0.0002103 45.0
HKD1_k127_434038_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0002705 54.0
HKD1_k127_4342046_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 490.0
HKD1_k127_4342046_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 384.0
HKD1_k127_4342046_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 362.0
HKD1_k127_4342046_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004446 291.0
HKD1_k127_4342046_4 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002883 289.0
HKD1_k127_4342046_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000721 275.0
HKD1_k127_4342046_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000001761 227.0
HKD1_k127_4342046_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000216 171.0
HKD1_k127_4342046_8 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000001657 138.0
HKD1_k127_4342046_9 Tetratricopeptide repeat - - - 0.00000000000000000000000001742 126.0
HKD1_k127_4400886_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 497.0
HKD1_k127_4400886_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
HKD1_k127_4400886_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 348.0
HKD1_k127_4400886_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 319.0
HKD1_k127_4400886_4 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 320.0
HKD1_k127_4400886_5 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005342 266.0
HKD1_k127_4400886_6 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000001557 239.0
HKD1_k127_4400886_7 protein involved in formation of curli polymers - - - 0.00000000000000000000000000000000000001334 156.0
HKD1_k127_4400886_8 Smr domain - - - 0.000000000000000000000007733 106.0
HKD1_k127_4400886_9 Histidine kinase - - - 0.00000000000000000001228 108.0
HKD1_k127_4461704_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 428.0
HKD1_k127_4461704_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000001121 219.0
HKD1_k127_4461704_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000001143 139.0
HKD1_k127_4461704_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000003548 105.0
HKD1_k127_447761_0 Coenzyme A transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 504.0
HKD1_k127_447761_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 393.0
HKD1_k127_447761_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 309.0
HKD1_k127_447761_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000003303 209.0
HKD1_k127_447761_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000001567 204.0
HKD1_k127_447761_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000004192 104.0
HKD1_k127_4487891_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 533.0
HKD1_k127_4487891_1 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 386.0
HKD1_k127_4487891_2 penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 357.0
HKD1_k127_4487891_3 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002505 282.0
HKD1_k127_4487891_4 PFAM glycosyl transferase family 39 K14340 - - 0.000000000000000000000000000000000000000000000000002535 203.0
HKD1_k127_4487891_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000001813 169.0
HKD1_k127_4487891_6 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000002122 121.0
HKD1_k127_4487891_7 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.000000000000000000000000004172 130.0
HKD1_k127_4487891_8 Bacterial membrane protein YfhO - - - 0.00000000000000000169 101.0
HKD1_k127_4487891_9 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000001142 65.0
HKD1_k127_4548185_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 475.0
HKD1_k127_4548185_1 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000006069 227.0
HKD1_k127_4548185_2 - - - - 0.0000000000000000000000000000000002018 134.0
HKD1_k127_4548185_3 - - - - 0.00000000000000000000001465 108.0
HKD1_k127_4548185_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000004253 96.0
HKD1_k127_4548185_5 - - - - 0.0000000000000000007831 91.0
HKD1_k127_4579377_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.347e-244 765.0
HKD1_k127_4579377_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000001784 173.0
HKD1_k127_4579377_2 nuclease activity - - - 0.00000000000000009347 87.0
HKD1_k127_468456_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002493 230.0
HKD1_k127_468456_1 BON domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0001474 54.0
HKD1_k127_472277_0 Voltage gated chloride channel - - - 3.242e-234 750.0
HKD1_k127_472277_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 516.0
HKD1_k127_472277_10 Signal peptidase, peptidase S26 - - - 0.00000000000000000000000000000000000000000000000001249 189.0
HKD1_k127_472277_11 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000003707 196.0
HKD1_k127_472277_12 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000454 188.0
HKD1_k127_472277_13 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000009126 165.0
HKD1_k127_472277_14 Peptidase C26 K07010 - - 0.00000000000000000000000000000002656 143.0
HKD1_k127_472277_15 OmpA family K03640 - - 0.0000000000000000000000000000000281 133.0
HKD1_k127_472277_16 Metallo-beta-lactamase superfamily - - - 0.0000000000000003579 93.0
HKD1_k127_472277_17 Belongs to the Fur family K09825 - - 0.0000000008558 61.0
HKD1_k127_472277_18 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000003284 63.0
HKD1_k127_472277_19 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0001016 54.0
HKD1_k127_472277_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 509.0
HKD1_k127_472277_3 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 476.0
HKD1_k127_472277_4 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 391.0
HKD1_k127_472277_5 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 398.0
HKD1_k127_472277_6 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000008783 243.0
HKD1_k127_472277_7 Dna alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000002455 239.0
HKD1_k127_472277_8 Belongs to the beta-ketoacyl-ACP synthases family K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.000000000000000000000000000000000000000000000000000000000000007058 235.0
HKD1_k127_472277_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000004069 200.0
HKD1_k127_474380_0 Large extracellular alpha-helical protein - - - 1.501e-219 688.0
HKD1_k127_474380_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 626.0
HKD1_k127_474380_10 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000001639 170.0
HKD1_k127_474380_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000002966 154.0
HKD1_k127_474380_12 - - - - 0.0000000000000000000000000000002212 129.0
HKD1_k127_474380_13 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000361 140.0
HKD1_k127_474380_14 Lysin motif - - - 0.00000000000000000001123 94.0
HKD1_k127_474380_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 432.0
HKD1_k127_474380_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 328.0
HKD1_k127_474380_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 294.0
HKD1_k127_474380_5 - - - - 0.000000000000000000000000000000000000000000000000007273 208.0
HKD1_k127_474380_6 Translation elongation factor P EF-P - - - 0.00000000000000000000000000000000000000000000002301 174.0
HKD1_k127_474380_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000004078 172.0
HKD1_k127_474380_8 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000003376 170.0
HKD1_k127_474380_9 FR47-like protein - - - 0.000000000000000000000000000000000000000001332 181.0
HKD1_k127_4752383_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000001197 121.0
HKD1_k127_4752383_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000005994 102.0
HKD1_k127_4752383_2 polysaccharide deacetylase - - - 0.00000000000000657 81.0
HKD1_k127_4752383_3 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000003708 77.0
HKD1_k127_4752383_4 polysaccharide deacetylase - - - 0.000000002647 64.0
HKD1_k127_4752383_5 Tetratricopeptide repeat - - - 0.00000007288 65.0
HKD1_k127_475252_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001312 259.0
HKD1_k127_475252_1 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003695 250.0
HKD1_k127_475252_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000006033 224.0
HKD1_k127_479005_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1243.0
HKD1_k127_479005_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1215.0
HKD1_k127_479005_10 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005833 246.0
HKD1_k127_479005_11 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000004514 256.0
HKD1_k127_479005_12 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000009004 183.0
HKD1_k127_479005_13 response regulator - - - 0.00000000000000000000000000000000000000000000000001896 191.0
HKD1_k127_479005_14 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000001055 205.0
HKD1_k127_479005_15 - - - - 0.00000000000000000000000000000000000000000001148 168.0
HKD1_k127_479005_16 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000002244 170.0
HKD1_k127_479005_17 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000004397 150.0
HKD1_k127_479005_18 cheY-homologous receiver domain - - - 0.00000000000000000000000000000002323 145.0
HKD1_k127_479005_19 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000004234 140.0
HKD1_k127_479005_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 3.087e-259 827.0
HKD1_k127_479005_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000613 141.0
HKD1_k127_479005_21 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000006071 108.0
HKD1_k127_479005_23 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000009844 109.0
HKD1_k127_479005_24 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000004103 98.0
HKD1_k127_479005_25 outer membrane autotransporter barrel domain protein - - - 0.000000000000003076 89.0
HKD1_k127_479005_26 Acetyl propionyl-CoA carboxylase alpha subunit K01968 - 6.4.1.4 0.00000000000006377 85.0
HKD1_k127_479005_27 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000009171 71.0
HKD1_k127_479005_28 PFAM glutaredoxin 2 - - - 0.00000000006455 73.0
HKD1_k127_479005_3 Carboxyl transferase domain K01969 - 6.4.1.4 3.54e-234 736.0
HKD1_k127_479005_4 Biotin carboxylase C-terminal domain K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 446.0
HKD1_k127_479005_5 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
HKD1_k127_479005_6 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 352.0
HKD1_k127_479005_7 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 321.0
HKD1_k127_479005_8 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001462 300.0
HKD1_k127_479005_9 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000003607 243.0
HKD1_k127_4846090_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 585.0
HKD1_k127_4846090_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 505.0
HKD1_k127_4846090_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000003793 141.0
HKD1_k127_4846090_11 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000001214 145.0
HKD1_k127_4846090_12 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000007789 140.0
HKD1_k127_4846090_13 AsnC family - - - 0.0000000000000000000000000000005543 130.0
HKD1_k127_4846090_14 Phosphoribosyl transferase domain - - - 0.00000000000000000000000009847 123.0
HKD1_k127_4846090_15 Methyltransferase - - - 0.000000000000000002954 95.0
HKD1_k127_4846090_16 PKD domain - - - 0.0000000000001874 86.0
HKD1_k127_4846090_17 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000006452 83.0
HKD1_k127_4846090_18 PFAM glycosyl transferase family 39 - - - 0.000000000005044 79.0
HKD1_k127_4846090_19 peptidyl-tyrosine sulfation - - - 0.0000000000153 77.0
HKD1_k127_4846090_2 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000534 299.0
HKD1_k127_4846090_20 PFAM glycosyl transferase group 1 - - - 0.00000000002083 78.0
HKD1_k127_4846090_21 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0000000001481 73.0
HKD1_k127_4846090_22 Acetyltransferase (GNAT) domain - - - 0.00000000052 71.0
HKD1_k127_4846090_23 PFAM PEGA domain - - - 0.000000007321 68.0
HKD1_k127_4846090_24 DNA polymerase III K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000002709 65.0
HKD1_k127_4846090_25 Helix-turn-helix - - - 0.00000033 57.0
HKD1_k127_4846090_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001299 293.0
HKD1_k127_4846090_4 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008195 286.0
HKD1_k127_4846090_5 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008825 259.0
HKD1_k127_4846090_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000005467 231.0
HKD1_k127_4846090_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000001409 244.0
HKD1_k127_4846090_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000001424 186.0
HKD1_k127_4846090_9 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000953 140.0
HKD1_k127_4887206_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 4.786e-214 690.0
HKD1_k127_4887206_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.182e-212 689.0
HKD1_k127_4887206_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000001913 235.0
HKD1_k127_4887206_3 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000003194 231.0
HKD1_k127_4887206_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000008519 126.0
HKD1_k127_4887206_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000004064 72.0
HKD1_k127_4887206_6 Protein of unknown function (DUF503) K09764 - - 0.00000000005491 68.0
HKD1_k127_4887206_7 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.0000000009336 72.0
HKD1_k127_4887659_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1037.0
HKD1_k127_4887659_1 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 3.711e-232 728.0
HKD1_k127_4887659_10 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000005015 264.0
HKD1_k127_4887659_11 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008046 256.0
HKD1_k127_4887659_12 TIGRFAM type VI secretion-associated protein, ImpA family K11902 - - 0.0000000000000000000000000000000000000000000000000000000000000000001729 243.0
HKD1_k127_4887659_13 TIGRFAM type VI secretion protein, VC_A0114 family K11893 - - 0.0000000000000000000000000000000000000000000000000000000000002141 235.0
HKD1_k127_4887659_14 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.000000000000000000000000000000000000000000000000000000000006801 213.0
HKD1_k127_4887659_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000164 214.0
HKD1_k127_4887659_16 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000000000000000003955 208.0
HKD1_k127_4887659_17 metal cluster binding - - - 0.000000000000000000000000000000000000000000000000000000001421 210.0
HKD1_k127_4887659_18 PFAM Dynamin family protein - - - 0.00000000000000000000000000000000000000000000001779 191.0
HKD1_k127_4887659_19 - - - - 0.00000000000000000000000000000000000000001114 168.0
HKD1_k127_4887659_2 TIGRFAM type VI secretion system Vgr family protein K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 616.0
HKD1_k127_4887659_20 PAAR motif - - - 0.00000000000000000000000000000000000000006826 167.0
HKD1_k127_4887659_21 Gene 25-like lysozyme K11897 - - 0.000000000000000000000000000000001341 136.0
HKD1_k127_4887659_22 Lipopolysaccharide kinase (Kdo/WaaP) family K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000001748 145.0
HKD1_k127_4887659_23 calcium- and calmodulin-responsive adenylate cyclase activity K11904 - - 0.000000000000000000000000000001132 136.0
HKD1_k127_4887659_24 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000131 136.0
HKD1_k127_4887659_25 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000003723 133.0
HKD1_k127_4887659_26 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000007304 131.0
HKD1_k127_4887659_27 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000003801 111.0
HKD1_k127_4887659_28 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000001403 109.0
HKD1_k127_4887659_29 HIT domain K02503 - - 0.000000000000000121 93.0
HKD1_k127_4887659_3 Pfam:T6SS_VipB K11896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 634.0
HKD1_k127_4887659_30 Forkhead associated domain - - - 0.00000000000001488 85.0
HKD1_k127_4887659_31 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000007434 76.0
HKD1_k127_4887659_32 Type VI secretion system protein DotU - - - 0.000000001694 67.0
HKD1_k127_4887659_33 - - - - 0.000000006922 65.0
HKD1_k127_4887659_34 protein conserved in bacteria - - - 0.00009672 55.0
HKD1_k127_4887659_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 445.0
HKD1_k127_4887659_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 440.0
HKD1_k127_4887659_6 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 361.0
HKD1_k127_4887659_7 type VI secretion protein K11900,K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 336.0
HKD1_k127_4887659_8 ImcF-related N-terminal domain K11891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 326.0
HKD1_k127_4887659_9 TIGRFAM type VI secretion protein, VC_A0111 family K11895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000684 297.0
HKD1_k127_5053180_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 312.0
HKD1_k127_5053180_1 - - - - 0.0000000000000000000002554 108.0
HKD1_k127_5071530_0 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 370.0
HKD1_k127_5071530_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 313.0
HKD1_k127_5071530_2 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000002038 131.0
HKD1_k127_5090118_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 410.0
HKD1_k127_5104039_0 - - - - 0.000000000000000000000000000000004372 143.0
HKD1_k127_5105489_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 611.0
HKD1_k127_5105489_1 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 526.0
HKD1_k127_5105489_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 502.0
HKD1_k127_5105489_3 ATP-dependent helicase activity K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 414.0
HKD1_k127_5105489_4 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000008153 234.0
HKD1_k127_5105489_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000005855 98.0
HKD1_k127_5114036_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.683e-245 788.0
HKD1_k127_5114036_1 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 398.0
HKD1_k127_5114036_2 Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 366.0
HKD1_k127_5114036_3 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000283 228.0
HKD1_k127_5114036_4 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000002082 203.0
HKD1_k127_5114036_6 domain, Protein - - - 0.000000000000002829 89.0
HKD1_k127_5114036_9 Aminotransferase class I and II K14267 - 2.6.1.17 0.0002769 49.0
HKD1_k127_5116399_0 enterobactin catabolic process - - - 4.659e-246 806.0
HKD1_k127_5116399_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 454.0
HKD1_k127_5116399_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 257.0
HKD1_k127_5116399_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002076 256.0
HKD1_k127_5116399_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000008647 123.0
HKD1_k127_5116399_5 PFAM Outer membrane efflux protein - - - 0.000000002775 69.0
HKD1_k127_5159862_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 6.123e-218 685.0
HKD1_k127_5159862_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 579.0
HKD1_k127_5159862_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003327 216.0
HKD1_k127_5159862_11 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000007423 216.0
HKD1_k127_5159862_12 amine dehydrogenase activity - - - 0.00000000000000000000000000001008 134.0
HKD1_k127_5159862_14 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000174 102.0
HKD1_k127_5159862_15 Histidine kinase K07711,K19694 - 2.7.13.3 0.0000000000000000077 94.0
HKD1_k127_5159862_16 von Willebrand factor, type A K07114 - - 0.0000000005845 73.0
HKD1_k127_5159862_17 oxidoreductase activity - - - 0.000000003323 70.0
HKD1_k127_5159862_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 482.0
HKD1_k127_5159862_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 411.0
HKD1_k127_5159862_4 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 398.0
HKD1_k127_5159862_5 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 399.0
HKD1_k127_5159862_6 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 369.0
HKD1_k127_5159862_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 347.0
HKD1_k127_5159862_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006883 281.0
HKD1_k127_5159862_9 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000208 232.0
HKD1_k127_5164861_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 3.063e-266 844.0
HKD1_k127_5164861_1 Erythromycin esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 564.0
HKD1_k127_5164861_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 523.0
HKD1_k127_5164861_3 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 363.0
HKD1_k127_5164861_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 349.0
HKD1_k127_5164861_5 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001461 239.0
HKD1_k127_5164861_6 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000008932 189.0
HKD1_k127_5164861_7 hydrolase of the alpha beta superfamily K07017 - - 0.0000000000000000000000000000000000000003738 158.0
HKD1_k127_5164861_8 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000001261 141.0
HKD1_k127_5169527_0 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 469.0
HKD1_k127_5169527_1 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 411.0
HKD1_k127_5169527_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 319.0
HKD1_k127_5169527_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000006237 232.0
HKD1_k127_5169527_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000001016 215.0
HKD1_k127_5169527_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000007772 182.0
HKD1_k127_5169527_6 CarboxypepD_reg-like domain - - - 0.000000000000000001399 92.0
HKD1_k127_5194339_0 Site-specific recombinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 411.0
HKD1_k127_5194339_1 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 311.0
HKD1_k127_5194339_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000001176 226.0
HKD1_k127_5194339_3 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000001059 205.0
HKD1_k127_5194339_4 conserved protein (DUF2075) K09384 - - 0.000000000000000000000000001151 115.0
HKD1_k127_5194339_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0000000000000000000001725 102.0
HKD1_k127_5194339_6 antitoxin component of a - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000004589 64.0
HKD1_k127_5205070_0 radical SAM domain protein K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 586.0
HKD1_k127_5205070_1 B12 binding domain K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 596.0
HKD1_k127_5205070_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000001259 203.0
HKD1_k127_5205070_12 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000785 100.0
HKD1_k127_5205070_13 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000001048 64.0
HKD1_k127_5205070_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 549.0
HKD1_k127_5205070_3 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 399.0
HKD1_k127_5205070_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 322.0
HKD1_k127_5205070_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 292.0
HKD1_k127_5205070_6 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001669 287.0
HKD1_k127_5205070_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001038 275.0
HKD1_k127_5205070_8 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004786 263.0
HKD1_k127_5205070_9 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000002988 248.0
HKD1_k127_5215497_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 8.405e-305 954.0
HKD1_k127_5215497_1 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 317.0
HKD1_k127_5215497_10 Aspartyl protease - - - 0.00008128 56.0
HKD1_k127_5215497_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000007167 256.0
HKD1_k127_5215497_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000002083 215.0
HKD1_k127_5215497_4 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000006119 172.0
HKD1_k127_5215497_5 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000000000000000000000000000141 169.0
HKD1_k127_5215497_6 protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000002643 131.0
HKD1_k127_5215497_7 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000004036 123.0
HKD1_k127_5215497_8 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000007573 98.0
HKD1_k127_5215497_9 antisigma factor binding - - - 0.00000000000000000001554 95.0
HKD1_k127_5223335_0 Carboxypeptidase regulatory-like domain - - - 0.0 1027.0
HKD1_k127_5223335_1 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 412.0
HKD1_k127_5223335_10 COGs COG3603 conserved K09707 - - 0.0000000000000812 83.0
HKD1_k127_5223335_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
HKD1_k127_5223335_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 323.0
HKD1_k127_5223335_4 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 310.0
HKD1_k127_5223335_5 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000005678 239.0
HKD1_k127_5223335_6 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000006927 223.0
HKD1_k127_5223335_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000932 201.0
HKD1_k127_5223335_8 - - - - 0.0000000000000007947 89.0
HKD1_k127_5223335_9 Domain of unknown function (DUF4833) - - - 0.000000000000002053 82.0
HKD1_k127_5225290_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 413.0
HKD1_k127_5225290_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 372.0
HKD1_k127_5225290_2 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 326.0
HKD1_k127_5225290_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001433 279.0
HKD1_k127_5225290_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003206 236.0
HKD1_k127_5225290_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000314 214.0
HKD1_k127_5225290_6 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000008566 143.0
HKD1_k127_5225290_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000002074 117.0
HKD1_k127_5225290_8 PFAM peptidase K21471 - - 0.00000000000000000000001061 118.0
HKD1_k127_5225290_9 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000008789 114.0
HKD1_k127_5240173_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 460.0
HKD1_k127_5240173_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 306.0
HKD1_k127_5240173_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002337 251.0
HKD1_k127_5240173_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000037 172.0
HKD1_k127_5240173_4 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000006673 177.0
HKD1_k127_5240173_5 TIGRFAM diguanylate cyclase - - - 0.0000000000000000000000000000000001494 154.0
HKD1_k127_5240173_6 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.0000000000000000000000000000000009882 144.0
HKD1_k127_529768_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 381.0
HKD1_k127_529768_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000004236 114.0
HKD1_k127_529768_2 GlcNAc-PI de-N-acetylase K22135 - - 0.00000000001078 73.0
HKD1_k127_5323323_0 4Fe-4S dicluster domain - - - 0.000000000000000000000001658 110.0
HKD1_k127_5323323_1 Cupin domain - - - 0.00000005577 54.0
HKD1_k127_5323323_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0003865 49.0
HKD1_k127_5335266_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1030.0
HKD1_k127_5335266_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.246e-208 665.0
HKD1_k127_5335266_10 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001829 297.0
HKD1_k127_5335266_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000002669 264.0
HKD1_k127_5335266_12 Cysteine dioxygenase type I - - - 0.000000000000000000000000000000000000000000000000000000000000000000489 237.0
HKD1_k127_5335266_13 Inhibitor of apoptosis-promoting Bax1 K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000002866 228.0
HKD1_k127_5335266_14 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000002566 212.0
HKD1_k127_5335266_15 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000005172 211.0
HKD1_k127_5335266_16 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000003056 126.0
HKD1_k127_5335266_17 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000001566 132.0
HKD1_k127_5335266_18 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000001541 119.0
HKD1_k127_5335266_19 Domain of unknown function (DUF4920) - - - 0.000000000000000000000001218 108.0
HKD1_k127_5335266_2 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 486.0
HKD1_k127_5335266_20 Sulfatase - - - 0.000000000000000002718 101.0
HKD1_k127_5335266_21 HxlR-like helix-turn-helix - - - 0.00000000000000008441 89.0
HKD1_k127_5335266_22 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000003666 70.0
HKD1_k127_5335266_23 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.000000003724 70.0
HKD1_k127_5335266_24 PQ loop repeat K15383 - - 0.00000003801 58.0
HKD1_k127_5335266_25 Cell division protein FtsQ K03589 - - 0.0000005043 60.0
HKD1_k127_5335266_26 Evidence 5 No homology to any previously reported sequences - - - 0.0001612 54.0
HKD1_k127_5335266_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 414.0
HKD1_k127_5335266_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 404.0
HKD1_k127_5335266_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 388.0
HKD1_k127_5335266_6 PASTA domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 389.0
HKD1_k127_5335266_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 332.0
HKD1_k127_5335266_8 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 326.0
HKD1_k127_5335266_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002708 281.0
HKD1_k127_5500604_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1088.0
HKD1_k127_5500604_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1043.0
HKD1_k127_5500604_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 385.0
HKD1_k127_5500604_11 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000006788 273.0
HKD1_k127_5500604_12 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001234 270.0
HKD1_k127_5500604_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000004729 226.0
HKD1_k127_5500604_14 SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000001478 189.0
HKD1_k127_5500604_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000007241 195.0
HKD1_k127_5500604_16 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000002267 186.0
HKD1_k127_5500604_17 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000009791 136.0
HKD1_k127_5500604_18 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000000001412 136.0
HKD1_k127_5500604_19 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000729 115.0
HKD1_k127_5500604_2 malic protein domain protein K00029 - 1.1.1.40 8.088e-292 914.0
HKD1_k127_5500604_20 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000000000000000000000001437 126.0
HKD1_k127_5500604_21 Globin - - - 0.0000000000000000000000003325 110.0
HKD1_k127_5500604_22 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000008317 122.0
HKD1_k127_5500604_23 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000001116 121.0
HKD1_k127_5500604_24 Putative ATP-binding cassette K01992 - - 0.00000000000000000008084 105.0
HKD1_k127_5500604_25 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.000000001705 70.0
HKD1_k127_5500604_26 Type ii and iii secretion system protein - - - 0.0002629 52.0
HKD1_k127_5500604_3 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 1.323e-235 746.0
HKD1_k127_5500604_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 1.18e-217 681.0
HKD1_k127_5500604_5 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 571.0
HKD1_k127_5500604_6 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 557.0
HKD1_k127_5500604_7 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 528.0
HKD1_k127_5500604_8 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 502.0
HKD1_k127_5500604_9 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 481.0
HKD1_k127_5518450_0 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000184 172.0
HKD1_k127_5518450_1 HD domain - - - 0.00000000000000000000000000000000000000000001106 185.0
HKD1_k127_5518450_2 - - - - 0.00000000000000000000000000000006082 145.0
HKD1_k127_5518450_3 serine-type endopeptidase activity K20276 - - 0.000000000000000000002037 108.0
HKD1_k127_5518450_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.0000000000001957 84.0
HKD1_k127_5543815_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.837e-268 844.0
HKD1_k127_5543815_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 3.61e-225 707.0
HKD1_k127_5543815_10 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000001446 247.0
HKD1_k127_5543815_11 cytochrome c nitrite reductase K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000209 239.0
HKD1_k127_5543815_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000002691 218.0
HKD1_k127_5543815_13 - - - - 0.000000000000000000000000000000000000000000000000000000000638 218.0
HKD1_k127_5543815_14 HlyD membrane-fusion protein of T1SS K01993 - - 0.00000000000000000000000000000000000000000004935 173.0
HKD1_k127_5543815_15 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000001733 110.0
HKD1_k127_5543815_16 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000001457 102.0
HKD1_k127_5543815_17 - - - - 0.00000000000000000615 87.0
HKD1_k127_5543815_18 Cbs domain K04767 - - 0.00000000000000002835 89.0
HKD1_k127_5543815_19 - K07234 - - 0.0000006405 62.0
HKD1_k127_5543815_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 518.0
HKD1_k127_5543815_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 475.0
HKD1_k127_5543815_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 439.0
HKD1_k127_5543815_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 377.0
HKD1_k127_5543815_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 403.0
HKD1_k127_5543815_7 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 332.0
HKD1_k127_5543815_8 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004387 270.0
HKD1_k127_5543815_9 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 256.0
HKD1_k127_5632449_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 525.0
HKD1_k127_5632449_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 435.0
HKD1_k127_5632449_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003173 254.0
HKD1_k127_5632449_3 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000008192 218.0
HKD1_k127_5632449_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000004795 109.0
HKD1_k127_5632449_5 FecR protein - - - 0.00003203 56.0
HKD1_k127_5632449_6 Probably functions as a manganese efflux pump - - - 0.0001506 51.0
HKD1_k127_5634827_0 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 496.0
HKD1_k127_5634827_1 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 364.0
HKD1_k127_5634827_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 329.0
HKD1_k127_5634827_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001183 228.0
HKD1_k127_5634827_4 Glycosyltransferase, group 2 family protein - - - 0.0001583 55.0
HKD1_k127_5696568_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.582e-231 748.0
HKD1_k127_5696568_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 9.407e-223 719.0
HKD1_k127_5696568_10 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 367.0
HKD1_k127_5696568_11 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 359.0
HKD1_k127_5696568_12 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 345.0
HKD1_k127_5696568_13 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 331.0
HKD1_k127_5696568_14 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 317.0
HKD1_k127_5696568_15 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 316.0
HKD1_k127_5696568_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 327.0
HKD1_k127_5696568_17 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 316.0
HKD1_k127_5696568_18 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001015 308.0
HKD1_k127_5696568_19 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
HKD1_k127_5696568_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 588.0
HKD1_k127_5696568_20 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000006404 254.0
HKD1_k127_5696568_21 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000001875 221.0
HKD1_k127_5696568_22 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000003038 222.0
HKD1_k127_5696568_23 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000001346 216.0
HKD1_k127_5696568_24 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000005126 195.0
HKD1_k127_5696568_25 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000009263 188.0
HKD1_k127_5696568_26 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000463 186.0
HKD1_k127_5696568_27 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000003076 187.0
HKD1_k127_5696568_28 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000008336 172.0
HKD1_k127_5696568_29 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000006249 183.0
HKD1_k127_5696568_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 530.0
HKD1_k127_5696568_30 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000000008081 163.0
HKD1_k127_5696568_31 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000004525 163.0
HKD1_k127_5696568_32 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000006293 176.0
HKD1_k127_5696568_33 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000009269 162.0
HKD1_k127_5696568_34 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000408 146.0
HKD1_k127_5696568_35 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000001203 142.0
HKD1_k127_5696568_36 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000001507 150.0
HKD1_k127_5696568_37 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000001808 127.0
HKD1_k127_5696568_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000003312 121.0
HKD1_k127_5696568_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000773 105.0
HKD1_k127_5696568_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 467.0
HKD1_k127_5696568_40 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000004118 109.0
HKD1_k127_5696568_41 protein-disulfide reductase activity - - - 0.0000000000000000002065 95.0
HKD1_k127_5696568_42 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000006116 91.0
HKD1_k127_5696568_43 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.000000000000005689 82.0
HKD1_k127_5696568_44 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000006527 82.0
HKD1_k127_5696568_45 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000003619 73.0
HKD1_k127_5696568_46 Domain of unknown function (DUF309) K09763 - - 0.00000000001447 75.0
HKD1_k127_5696568_47 Mitochondrial biogenesis AIM24 - - - 0.00000000002225 77.0
HKD1_k127_5696568_48 - - - - 0.00000000004905 70.0
HKD1_k127_5696568_49 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.0000000001507 73.0
HKD1_k127_5696568_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 456.0
HKD1_k127_5696568_51 Yip1 domain - - - 0.00007905 55.0
HKD1_k127_5696568_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 453.0
HKD1_k127_5696568_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 403.0
HKD1_k127_5696568_8 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 416.0
HKD1_k127_5696568_9 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 389.0
HKD1_k127_600549_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 600.0
HKD1_k127_600549_1 Belongs to the OprB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 573.0
HKD1_k127_600549_10 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
HKD1_k127_600549_11 cellular modified histidine biosynthetic process K18802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004343 251.0
HKD1_k127_600549_12 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000002528 256.0
HKD1_k127_600549_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000002777 228.0
HKD1_k127_600549_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000872 193.0
HKD1_k127_600549_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000003366 177.0
HKD1_k127_600549_16 cellulase activity - - - 0.0000000000000000000000000000000000000000000000246 192.0
HKD1_k127_600549_17 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000003768 144.0
HKD1_k127_600549_18 SnoaL-like domain - - - 0.00000000000000000000000000006112 120.0
HKD1_k127_600549_19 heme binding - - - 0.00000000000000000000003376 111.0
HKD1_k127_600549_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 556.0
HKD1_k127_600549_20 Phage integrase family - - - 0.00000000000000000003374 96.0
HKD1_k127_600549_21 amine dehydrogenase activity - - - 0.00000000000139 80.0
HKD1_k127_600549_22 Protein of unknown function (DUF1501) - - - 0.000000000001705 81.0
HKD1_k127_600549_23 Ferritin-like domain - - - 0.000000000003659 72.0
HKD1_k127_600549_24 amine dehydrogenase activity - - - 0.0003162 49.0
HKD1_k127_600549_3 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 502.0
HKD1_k127_600549_4 hydrolase family 57 K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 403.0
HKD1_k127_600549_5 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 402.0
HKD1_k127_600549_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 317.0
HKD1_k127_600549_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 302.0
HKD1_k127_600549_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000101 284.0
HKD1_k127_600549_9 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002582 289.0
HKD1_k127_604567_0 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000094 278.0
HKD1_k127_604567_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000593 192.0
HKD1_k127_604567_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000002505 122.0
HKD1_k127_6055329_0 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 348.0
HKD1_k127_6055329_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 304.0
HKD1_k127_6061683_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1572.0
HKD1_k127_6061683_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 531.0
HKD1_k127_6061683_10 Outer membrane efflux protein - - - 0.000000000000000007789 97.0
HKD1_k127_6061683_11 Tetratricopeptide repeat - - - 0.00000000000606 79.0
HKD1_k127_6061683_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 364.0
HKD1_k127_6061683_3 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005491 286.0
HKD1_k127_6061683_4 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001804 284.0
HKD1_k127_6061683_5 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000006427 218.0
HKD1_k127_6061683_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000006523 208.0
HKD1_k127_6061683_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000001675 156.0
HKD1_k127_6061683_8 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000007887 145.0
HKD1_k127_6061683_9 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000000000000000000000000001141 133.0
HKD1_k127_6063310_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 501.0
HKD1_k127_6063310_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000001768 190.0
HKD1_k127_6067586_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1519.0
HKD1_k127_6067586_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 567.0
HKD1_k127_6067586_10 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000009948 209.0
HKD1_k127_6067586_11 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000313 196.0
HKD1_k127_6067586_12 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000002023 184.0
HKD1_k127_6067586_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000003485 182.0
HKD1_k127_6067586_14 - - - - 0.000000000000000000000000001182 122.0
HKD1_k127_6067586_15 nuclear chromosome segregation - - - 0.00000000000000000000001711 115.0
HKD1_k127_6067586_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000375 93.0
HKD1_k127_6067586_17 nuclear chromosome segregation - - - 0.000000000000000001142 98.0
HKD1_k127_6067586_18 Regulatory protein - - - 0.00000000000000001591 90.0
HKD1_k127_6067586_19 Domain of unknown function (DUF3943) - - - 0.00000000000000002845 93.0
HKD1_k127_6067586_2 Sigma-54 interaction domain K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 528.0
HKD1_k127_6067586_21 polysaccharide deacetylase - - - 0.000000000008432 79.0
HKD1_k127_6067586_22 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000008685 59.0
HKD1_k127_6067586_23 phosphate regulon transcriptional regulatory protein PhoB K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000497 55.0
HKD1_k127_6067586_24 Major facilitator Superfamily - - - 0.0003254 48.0
HKD1_k127_6067586_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 532.0
HKD1_k127_6067586_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 477.0
HKD1_k127_6067586_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 471.0
HKD1_k127_6067586_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 444.0
HKD1_k127_6067586_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 354.0
HKD1_k127_6067586_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 340.0
HKD1_k127_6067586_9 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000008719 218.0
HKD1_k127_6068414_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1474.0
HKD1_k127_6068414_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 490.0
HKD1_k127_6068414_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 441.0
HKD1_k127_6068414_3 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 293.0
HKD1_k127_6068414_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003525 259.0
HKD1_k127_6068414_5 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K10672,K10794 - 1.21.4.1,1.21.4.2 0.0000000000000000000000000000000000000000000001145 173.0
HKD1_k127_6068414_6 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000001803 151.0
HKD1_k127_6068414_7 pathogenesis K00631,K01897 - 2.3.1.15,6.2.1.3 0.000000000000000003549 99.0
HKD1_k127_6068414_8 - - - - 0.0000000000003344 72.0
HKD1_k127_6101949_0 Oligoendopeptidase f - - - 2.176e-280 876.0
HKD1_k127_6101949_1 O-acetylhomoserine K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 505.0
HKD1_k127_6101949_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 422.0
HKD1_k127_6101949_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001769 298.0
HKD1_k127_6101949_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000008945 136.0
HKD1_k127_6101949_5 RNA recognition motif - - - 0.000000000000000000000007095 119.0
HKD1_k127_6101949_7 DNA-templated transcription, initiation K03088 - - 0.00000001553 57.0
HKD1_k127_6104267_0 Large extracellular alpha-helical protein - - - 0.0 1896.0
HKD1_k127_6104267_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 567.0
HKD1_k127_6104267_10 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 339.0
HKD1_k127_6104267_11 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 339.0
HKD1_k127_6104267_12 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 350.0
HKD1_k127_6104267_13 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 313.0
HKD1_k127_6104267_14 RNA polymerase recycling family C-terminal K03580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000434 306.0
HKD1_k127_6104267_15 Hep Hag repeat protein K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000023 290.0
HKD1_k127_6104267_16 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006599 278.0
HKD1_k127_6104267_17 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001653 291.0
HKD1_k127_6104267_18 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002885 258.0
HKD1_k127_6104267_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000004392 249.0
HKD1_k127_6104267_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 541.0
HKD1_k127_6104267_20 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000239 250.0
HKD1_k127_6104267_21 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
HKD1_k127_6104267_22 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000008791 233.0
HKD1_k127_6104267_23 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000125 213.0
HKD1_k127_6104267_24 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000004465 211.0
HKD1_k127_6104267_25 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000000000000000000001662 207.0
HKD1_k127_6104267_26 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000008718 184.0
HKD1_k127_6104267_27 - - - - 0.0000000000000000000000000000000000000000000002109 186.0
HKD1_k127_6104267_28 cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000001887 179.0
HKD1_k127_6104267_29 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000002063 184.0
HKD1_k127_6104267_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00493 - 1.14.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 504.0
HKD1_k127_6104267_30 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000008485 176.0
HKD1_k127_6104267_31 TIGRFAM DNA repair protein RadC K03630 - - 0.000000000000000000000000000000000000000001319 175.0
HKD1_k127_6104267_32 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000001018 137.0
HKD1_k127_6104267_33 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000007553 148.0
HKD1_k127_6104267_34 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000003539 129.0
HKD1_k127_6104267_35 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000003266 122.0
HKD1_k127_6104267_36 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000001446 117.0
HKD1_k127_6104267_37 Zincin-like metallopeptidase - - - 0.00000000000000000000000982 104.0
HKD1_k127_6104267_38 Ankyrin repeats (many copies) - - - 0.0000000000000000005001 98.0
HKD1_k127_6104267_39 Transglutaminase-like superfamily - - - 0.0000000000000000005428 99.0
HKD1_k127_6104267_4 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 460.0
HKD1_k127_6104267_40 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000134 93.0
HKD1_k127_6104267_41 polysaccharide deacetylase K15531 - 3.2.1.156 0.000000000000003208 90.0
HKD1_k127_6104267_42 heat shock protein binding - - - 0.00000000000005306 88.0
HKD1_k127_6104267_43 mttA/Hcf106 family K03116 - - 0.000000000000623 73.0
HKD1_k127_6104267_45 Belongs to the peptidase S8 family - - - 0.00000000001137 78.0
HKD1_k127_6104267_46 Outer membrane protein W K07275 - - 0.0000001736 60.0
HKD1_k127_6104267_47 - - - - 0.0000002055 58.0
HKD1_k127_6104267_48 - K07039 - - 0.0001166 52.0
HKD1_k127_6104267_49 Esterase PHB depolymerase - - - 0.0006241 51.0
HKD1_k127_6104267_5 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 433.0
HKD1_k127_6104267_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 426.0
HKD1_k127_6104267_7 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 415.0
HKD1_k127_6104267_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 378.0
HKD1_k127_6104267_9 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 353.0
HKD1_k127_6108442_0 Fungalysin metallopeptidase (M36) - - - 3.384e-298 977.0
HKD1_k127_6108442_1 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 2.875e-194 616.0
HKD1_k127_6108442_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 419.0
HKD1_k127_6108442_3 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 436.0
HKD1_k127_6108442_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 407.0
HKD1_k127_6108442_5 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 347.0
HKD1_k127_6108442_6 DinB superfamily - - - 0.000000000000000000000000000000000000000009893 159.0
HKD1_k127_6108442_7 Cbs domain K04767 - - 0.0000000000001694 84.0
HKD1_k127_6118998_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 615.0
HKD1_k127_6118998_1 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 542.0
HKD1_k127_6118998_10 LysE type translocator - - - 0.0000000005315 70.0
HKD1_k127_6118998_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 493.0
HKD1_k127_6118998_3 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001112 282.0
HKD1_k127_6118998_4 serine-type endopeptidase activity K08372 - - 0.000000000000000000000000000000000000000000000000000000000000005496 238.0
HKD1_k127_6118998_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.000000000000000000000000000000000000000000000000000002419 215.0
HKD1_k127_6118998_6 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000008836 134.0
HKD1_k127_6118998_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000001179 129.0
HKD1_k127_6118998_8 Thioredoxin-like - - - 0.0000000000000000000000001148 116.0
HKD1_k127_6118998_9 Redoxin - - - 0.000000000000000000002852 99.0
HKD1_k127_6123864_0 Protein kinase domain K12132 - 2.7.11.1 3.205e-256 829.0
HKD1_k127_6123864_1 Peptidase dimerisation domain - - - 1.715e-198 632.0
HKD1_k127_6123864_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000005902 258.0
HKD1_k127_6123864_3 manganese ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000113 188.0
HKD1_k127_6123864_4 - - - - 0.00000000000001952 87.0
HKD1_k127_6123864_5 - - - - 0.0000000001388 76.0
HKD1_k127_6148747_0 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 398.0
HKD1_k127_6148747_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000794 301.0
HKD1_k127_6148747_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004283 288.0
HKD1_k127_6148747_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000546 141.0
HKD1_k127_6148747_4 - - - - 0.000000000000000000000000000000001874 136.0
HKD1_k127_6148807_0 Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 454.0
HKD1_k127_6148807_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 404.0
HKD1_k127_6148807_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 336.0
HKD1_k127_6148807_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006965 261.0
HKD1_k127_6148807_4 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005893 256.0
HKD1_k127_6148807_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000005909 207.0
HKD1_k127_6148807_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000005418 184.0
HKD1_k127_6148807_7 - - - - 0.000000000000000000000000000000000002935 144.0
HKD1_k127_6148807_8 CoA-binding protein K06929 - - 0.00000000000000001695 89.0
HKD1_k127_6148807_9 RibD C-terminal domain - - - 0.00000000000000003522 83.0
HKD1_k127_6149263_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.773e-256 802.0
HKD1_k127_6149263_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.206e-239 749.0
HKD1_k127_6149263_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000001474 258.0
HKD1_k127_6149263_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000008528 243.0
HKD1_k127_6149263_12 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000002097 213.0
HKD1_k127_6149263_13 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000001023 211.0
HKD1_k127_6149263_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000001037 192.0
HKD1_k127_6149263_15 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000007747 185.0
HKD1_k127_6149263_16 - - - - 0.0000000000000000000000000000000000001649 144.0
HKD1_k127_6149263_17 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000004259 162.0
HKD1_k127_6149263_18 Belongs to the BshC family K22136 - - 0.00000000000000000000000000000000009086 152.0
HKD1_k127_6149263_19 Polymer-forming cytoskeletal - - - 0.00000000000000001016 96.0
HKD1_k127_6149263_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.09e-225 712.0
HKD1_k127_6149263_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000001408 90.0
HKD1_k127_6149263_21 COG0671 Membrane-associated phospholipid phosphatase - - - 0.000000000000002018 90.0
HKD1_k127_6149263_22 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000004901 83.0
HKD1_k127_6149263_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000005819 81.0
HKD1_k127_6149263_24 Putative zinc- or iron-chelating domain - - - 0.00000000000001031 82.0
HKD1_k127_6149263_25 Preprotein translocase SecG subunit K03075 - - 0.00000000000001501 83.0
HKD1_k127_6149263_26 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) K04762 - - 0.0000000000305 73.0
HKD1_k127_6149263_27 - - - - 0.00000000009452 72.0
HKD1_k127_6149263_28 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000001007 66.0
HKD1_k127_6149263_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 558.0
HKD1_k127_6149263_30 RDD family - - - 0.0009655 53.0
HKD1_k127_6149263_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 446.0
HKD1_k127_6149263_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 402.0
HKD1_k127_6149263_6 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 395.0
HKD1_k127_6149263_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 314.0
HKD1_k127_6149263_8 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 312.0
HKD1_k127_6149263_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000001684 261.0
HKD1_k127_6150661_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.355e-229 735.0
HKD1_k127_6150661_1 2 heme-binding sites K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 518.0
HKD1_k127_6150661_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000002465 108.0
HKD1_k127_6150661_3 polysaccharide deacetylase - - - 0.000000000000000005115 89.0
HKD1_k127_6171352_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1299.0
HKD1_k127_6171352_1 Sortilin, neurotensin receptor 3, - - - 0.0 1291.0
HKD1_k127_6171352_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 330.0
HKD1_k127_6171352_11 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000004602 258.0
HKD1_k127_6171352_12 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
HKD1_k127_6171352_13 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000007797 241.0
HKD1_k127_6171352_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000006579 173.0
HKD1_k127_6171352_15 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000004347 156.0
HKD1_k127_6171352_16 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000156 106.0
HKD1_k127_6171352_17 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000002082 85.0
HKD1_k127_6171352_19 Putative regulatory protein - - - 0.00001271 50.0
HKD1_k127_6171352_2 Protein of unknown function (DUF3604) - - - 2.733e-250 788.0
HKD1_k127_6171352_3 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 3.96e-242 760.0
HKD1_k127_6171352_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 595.0
HKD1_k127_6171352_5 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 562.0
HKD1_k127_6171352_6 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 447.0
HKD1_k127_6171352_7 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 402.0
HKD1_k127_6171352_8 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 371.0
HKD1_k127_6171352_9 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 364.0
HKD1_k127_6173570_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 422.0
HKD1_k127_6173570_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002689 282.0
HKD1_k127_6173570_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000001599 197.0
HKD1_k127_6173570_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.000000000000000000000000000000000000000000000004441 198.0
HKD1_k127_6173570_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000008653 138.0
HKD1_k127_6173570_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003366 289.0
HKD1_k127_6173570_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000004062 285.0
HKD1_k127_6173570_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000007029 250.0
HKD1_k127_6173570_5 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000002633 245.0
HKD1_k127_6173570_6 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000001136 240.0
HKD1_k127_6173570_7 Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000005672 207.0
HKD1_k127_6173570_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.00000000000000000000000000000000000000000000000000000817 213.0
HKD1_k127_6173570_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000001036 193.0
HKD1_k127_6179538_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 363.0
HKD1_k127_6179538_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 303.0
HKD1_k127_6179538_10 helix_turn_helix, Lux Regulon - - - 0.0000000003381 68.0
HKD1_k127_6179538_11 response regulator - - - 0.0000000007859 65.0
HKD1_k127_6179538_13 Domain of unknown function (DUF4388) - - - 0.0000005706 63.0
HKD1_k127_6179538_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006103 255.0
HKD1_k127_6179538_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000009755 235.0
HKD1_k127_6179538_4 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000007206 232.0
HKD1_k127_6179538_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000001293 181.0
HKD1_k127_6179538_6 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000001323 129.0
HKD1_k127_6179538_7 GAF domain - - - 0.00000000000000000000000000005318 133.0
HKD1_k127_6179538_8 response regulator - - - 0.00000000000001168 78.0
HKD1_k127_6179538_9 phosphorelay signal transduction system K19622 - - 0.00000000007052 70.0
HKD1_k127_6204737_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 535.0
HKD1_k127_6204737_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 558.0
HKD1_k127_6204737_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 453.0
HKD1_k127_6204737_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 357.0
HKD1_k127_6204737_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000009993 235.0
HKD1_k127_6204737_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000724 159.0
HKD1_k127_6204737_6 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000002634 138.0
HKD1_k127_6204737_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000004644 111.0
HKD1_k127_6204737_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000002357 115.0
HKD1_k127_6204737_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000001338 111.0
HKD1_k127_6205_0 4Fe-4S dicluster domain K00184 - - 1.5e-323 1019.0
HKD1_k127_6205_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 631.0
HKD1_k127_6205_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 307.0
HKD1_k127_6205_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000006278 219.0
HKD1_k127_6205_4 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000004133 208.0
HKD1_k127_6206321_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1076.0
HKD1_k127_6206321_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.417e-311 968.0
HKD1_k127_6206321_10 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 605.0
HKD1_k127_6206321_11 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 549.0
HKD1_k127_6206321_12 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 539.0
HKD1_k127_6206321_13 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 508.0
HKD1_k127_6206321_14 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 509.0
HKD1_k127_6206321_15 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 473.0
HKD1_k127_6206321_16 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 462.0
HKD1_k127_6206321_17 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 429.0
HKD1_k127_6206321_18 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 447.0
HKD1_k127_6206321_19 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 424.0
HKD1_k127_6206321_2 COGs COG0374 Ni Fe-hydrogenase I large subunit K06281 - 1.12.99.6 4.44e-299 925.0
HKD1_k127_6206321_20 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 430.0
HKD1_k127_6206321_21 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 390.0
HKD1_k127_6206321_22 domain, Protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 388.0
HKD1_k127_6206321_23 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 385.0
HKD1_k127_6206321_24 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 360.0
HKD1_k127_6206321_25 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 346.0
HKD1_k127_6206321_26 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 336.0
HKD1_k127_6206321_27 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 319.0
HKD1_k127_6206321_28 Inner membrane protein CreD K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 308.0
HKD1_k127_6206321_29 Monogalactosyldiacylglycerol (MGDG) synthase K03429,K03715 - 2.4.1.315,2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 297.0
HKD1_k127_6206321_3 DNA topoisomerase K02470,K02622 - 5.99.1.3 1.545e-285 889.0
HKD1_k127_6206321_30 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 312.0
HKD1_k127_6206321_31 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 308.0
HKD1_k127_6206321_32 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 281.0
HKD1_k127_6206321_33 response regulator K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006013 286.0
HKD1_k127_6206321_34 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000762 294.0
HKD1_k127_6206321_35 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005925 302.0
HKD1_k127_6206321_36 PFAM BMC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001424 264.0
HKD1_k127_6206321_37 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004624 246.0
HKD1_k127_6206321_38 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005231 266.0
HKD1_k127_6206321_39 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006359 249.0
HKD1_k127_6206321_4 Belongs to the carbamoyltransferase HypF family K04656 - - 7.804e-251 797.0
HKD1_k127_6206321_40 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007999 253.0
HKD1_k127_6206321_41 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002564 248.0
HKD1_k127_6206321_42 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000001282 249.0
HKD1_k127_6206321_43 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000005528 233.0
HKD1_k127_6206321_44 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003508 232.0
HKD1_k127_6206321_45 - - - - 0.000000000000000000000000000000000000000000000000000000001285 221.0
HKD1_k127_6206321_46 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189,K04652 - - 0.0000000000000000000000000000000000000000000000000000006514 218.0
HKD1_k127_6206321_47 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000161 196.0
HKD1_k127_6206321_48 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.0000000000000000000000000000000000000000000000000124 205.0
HKD1_k127_6206321_49 Peptidase M50 K16922 - - 0.00000000000000000000000000000000000000000000000002823 207.0
HKD1_k127_6206321_5 PFAM peptidase S16 lon domain protein - - - 2.594e-239 771.0
HKD1_k127_6206321_51 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000004961 184.0
HKD1_k127_6206321_52 phosphatase activity K01560,K07025,K08723,K20862 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 0.00000000000000000000000000000000000000000001141 171.0
HKD1_k127_6206321_53 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000001885 178.0
HKD1_k127_6206321_54 FAD linked oxidases, C-terminal domain K18930 - - 0.00000000000000000000000000000000000000000002068 166.0
HKD1_k127_6206321_55 N-acetylglucosamine kinase activity K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.0000000000000000000000000000000000000008242 160.0
HKD1_k127_6206321_56 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000001694 158.0
HKD1_k127_6206321_57 PFAM TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000002214 161.0
HKD1_k127_6206321_58 BMC K04027 - - 0.000000000000000000000000000000000007944 138.0
HKD1_k127_6206321_59 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000004088 151.0
HKD1_k127_6206321_6 Malate synthase K01638 - 2.3.3.9 6.334e-232 737.0
HKD1_k127_6206321_60 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000002913 147.0
HKD1_k127_6206321_61 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000005829 121.0
HKD1_k127_6206321_62 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000001909 118.0
HKD1_k127_6206321_63 cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000003187 118.0
HKD1_k127_6206321_64 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000001045 114.0
HKD1_k127_6206321_65 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000002803 115.0
HKD1_k127_6206321_66 HupF/HypC family K04653 - - 0.0000000000000000000009324 97.0
HKD1_k127_6206321_67 Belongs to the globin family - - - 0.000000000000000000008926 104.0
HKD1_k127_6206321_68 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000000000001881 99.0
HKD1_k127_6206321_69 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000001521 89.0
HKD1_k127_6206321_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 1.339e-221 693.0
HKD1_k127_6206321_70 thiolester hydrolase activity K06889,K07000 - - 0.000000000000000002445 94.0
HKD1_k127_6206321_71 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000002701 96.0
HKD1_k127_6206321_72 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000008694 91.0
HKD1_k127_6206321_73 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000001183 81.0
HKD1_k127_6206321_74 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000000001416 74.0
HKD1_k127_6206321_75 nickel cation binding K04651 - - 0.00000000000349 71.0
HKD1_k127_6206321_76 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000006638 76.0
HKD1_k127_6206321_78 - - - - 0.0000000156 66.0
HKD1_k127_6206321_79 acetyltransferase - - - 0.000000165 64.0
HKD1_k127_6206321_8 Cytochrome c - - - 1.352e-195 620.0
HKD1_k127_6206321_80 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000002535 61.0
HKD1_k127_6206321_81 Belongs to the peptidase S8 family - - - 0.0000535 57.0
HKD1_k127_6206321_9 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 594.0
HKD1_k127_620791_0 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 571.0
HKD1_k127_620791_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 510.0
HKD1_k127_620791_10 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000006929 207.0
HKD1_k127_620791_11 Major facilitator Superfamily K06902 - - 0.000000000000000000000000000000000000000000000000009754 204.0
HKD1_k127_620791_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000001048 179.0
HKD1_k127_620791_13 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000001248 166.0
HKD1_k127_620791_14 serine-type peptidase activity K01061,K06889 - 3.1.1.45 0.000000000000000000000000000000000000000001314 178.0
HKD1_k127_620791_15 GAF domain - - - 0.000000000000000000000000000000000000000002796 170.0
HKD1_k127_620791_16 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000000001389 164.0
HKD1_k127_620791_17 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.00000000000000000000000000000000000000007627 171.0
HKD1_k127_620791_18 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000001005 139.0
HKD1_k127_620791_19 regulation of translation K03530 - - 0.00000000000000000000000000000007288 127.0
HKD1_k127_620791_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 490.0
HKD1_k127_620791_20 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000001205 141.0
HKD1_k127_620791_21 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000001242 94.0
HKD1_k127_620791_22 domain, Protein - - - 0.00000000000089 81.0
HKD1_k127_620791_23 Oxygen tolerance - - - 0.000000000001951 81.0
HKD1_k127_620791_24 cytochrome complex assembly K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.000001912 61.0
HKD1_k127_620791_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 405.0
HKD1_k127_620791_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 394.0
HKD1_k127_620791_5 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 297.0
HKD1_k127_620791_6 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001431 267.0
HKD1_k127_620791_7 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000001079 252.0
HKD1_k127_620791_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000008942 243.0
HKD1_k127_620791_9 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000004738 218.0
HKD1_k127_6211917_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1230.0
HKD1_k127_6211917_1 Uncharacterized protein family (UPF0051) K09014 - - 4.519e-261 820.0
HKD1_k127_6211917_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 513.0
HKD1_k127_6211917_11 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 454.0
HKD1_k127_6211917_12 NhaP-type Na H and K H antiporters K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 422.0
HKD1_k127_6211917_13 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 413.0
HKD1_k127_6211917_14 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 401.0
HKD1_k127_6211917_15 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 373.0
HKD1_k127_6211917_16 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 376.0
HKD1_k127_6211917_17 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 363.0
HKD1_k127_6211917_18 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 337.0
HKD1_k127_6211917_19 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 346.0
HKD1_k127_6211917_2 ERAP1-like C-terminal domain K01263 - 3.4.11.14 4.644e-223 721.0
HKD1_k127_6211917_20 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 335.0
HKD1_k127_6211917_21 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 317.0
HKD1_k127_6211917_22 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 300.0
HKD1_k127_6211917_23 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 302.0
HKD1_k127_6211917_24 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007635 258.0
HKD1_k127_6211917_25 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002735 250.0
HKD1_k127_6211917_26 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000002578 238.0
HKD1_k127_6211917_27 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000001722 210.0
HKD1_k127_6211917_28 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000007407 203.0
HKD1_k127_6211917_29 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000001232 197.0
HKD1_k127_6211917_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 596.0
HKD1_k127_6211917_30 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000003053 171.0
HKD1_k127_6211917_31 Transcriptional regulator - - - 0.0000000000000000000000000000000001042 139.0
HKD1_k127_6211917_32 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.000000000000000000000000000000005649 135.0
HKD1_k127_6211917_33 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000003653 115.0
HKD1_k127_6211917_34 Bacterial membrane protein YfhO - - - 0.000000000000000008883 98.0
HKD1_k127_6211917_35 - - - - 0.000000000000000353 89.0
HKD1_k127_6211917_36 YsiA-like protein, C-terminal region K13770 - - 0.0000000000001134 79.0
HKD1_k127_6211917_37 C-terminal domain of CHU protein family - - - 0.000805 53.0
HKD1_k127_6211917_4 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 561.0
HKD1_k127_6211917_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 543.0
HKD1_k127_6211917_6 PFAM Peptidase S10, serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 551.0
HKD1_k127_6211917_7 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 554.0
HKD1_k127_6211917_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 509.0
HKD1_k127_6211917_9 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 522.0
HKD1_k127_6234036_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 333.0
HKD1_k127_6234036_1 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000006048 127.0
HKD1_k127_6234036_2 lipolytic protein G-D-S-L family - - - 0.000000000000006073 87.0
HKD1_k127_6274036_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 3.304e-204 644.0
HKD1_k127_6274036_1 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 576.0
HKD1_k127_6274036_10 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 294.0
HKD1_k127_6274036_11 PFAM C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000004069 260.0
HKD1_k127_6274036_12 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009754 242.0
HKD1_k127_6274036_13 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000002829 223.0
HKD1_k127_6274036_14 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000007358 219.0
HKD1_k127_6274036_15 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000001422 228.0
HKD1_k127_6274036_16 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001024 210.0
HKD1_k127_6274036_17 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000006871 197.0
HKD1_k127_6274036_18 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000797 173.0
HKD1_k127_6274036_19 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000002588 173.0
HKD1_k127_6274036_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 562.0
HKD1_k127_6274036_20 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000267 175.0
HKD1_k127_6274036_21 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000003675 161.0
HKD1_k127_6274036_22 lactate metabolic process - - - 0.0000000000000000000000000000000000005106 149.0
HKD1_k127_6274036_23 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000266 127.0
HKD1_k127_6274036_24 Thioredoxin-like - - - 0.00000000000000000003194 100.0
HKD1_k127_6274036_25 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000001396 91.0
HKD1_k127_6274036_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 457.0
HKD1_k127_6274036_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 382.0
HKD1_k127_6274036_5 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 374.0
HKD1_k127_6274036_6 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 349.0
HKD1_k127_6274036_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 346.0
HKD1_k127_6274036_8 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 337.0
HKD1_k127_6274036_9 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 297.0
HKD1_k127_6275208_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 558.0
HKD1_k127_6275208_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0000001295 57.0
HKD1_k127_6279525_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 473.0
HKD1_k127_6279525_1 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 0.000000000001516 68.0
HKD1_k127_6309259_0 PFAM response regulator receiver K07713 - - 6.824e-196 621.0
HKD1_k127_6309259_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 609.0
HKD1_k127_6309259_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
HKD1_k127_6309259_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001854 237.0
HKD1_k127_6309259_12 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000000000000003104 216.0
HKD1_k127_6309259_13 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000642 232.0
HKD1_k127_6309259_14 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000009163 207.0
HKD1_k127_6309259_15 PHP domain K04477 - - 0.000000000000000000000000000000000000000000000000001632 196.0
HKD1_k127_6309259_16 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000007582 179.0
HKD1_k127_6309259_17 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000002042 185.0
HKD1_k127_6309259_18 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000601 175.0
HKD1_k127_6309259_19 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000006399 139.0
HKD1_k127_6309259_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 532.0
HKD1_k127_6309259_20 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000001432 140.0
HKD1_k127_6309259_21 Belongs to the Fur family K03711 - - 0.000000000000000000000000000002978 140.0
HKD1_k127_6309259_23 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000001447 107.0
HKD1_k127_6309259_24 Ribonuclease K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000002561 116.0
HKD1_k127_6309259_25 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000005188 94.0
HKD1_k127_6309259_26 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000003037 96.0
HKD1_k127_6309259_27 PFAM DivIVA family protein K04074 - - 0.00000000000001837 80.0
HKD1_k127_6309259_28 C4-type zinc ribbon domain K07164 - - 0.00000000000006061 82.0
HKD1_k127_6309259_3 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 458.0
HKD1_k127_6309259_30 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000003312 67.0
HKD1_k127_6309259_31 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000156 71.0
HKD1_k127_6309259_32 nuclear chromosome segregation - - - 0.0000000001319 74.0
HKD1_k127_6309259_33 proteolysis - - - 0.000000001479 68.0
HKD1_k127_6309259_4 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 392.0
HKD1_k127_6309259_5 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 383.0
HKD1_k127_6309259_6 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 352.0
HKD1_k127_6309259_7 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 356.0
HKD1_k127_6309259_8 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 340.0
HKD1_k127_6309259_9 NeuB family K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005524 299.0
HKD1_k127_6320225_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.446e-239 754.0
HKD1_k127_6320225_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 2.851e-203 657.0
HKD1_k127_6320225_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
HKD1_k127_6320225_11 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 302.0
HKD1_k127_6320225_12 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004262 286.0
HKD1_k127_6320225_13 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005769 278.0
HKD1_k127_6320225_14 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001292 286.0
HKD1_k127_6320225_15 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000004555 270.0
HKD1_k127_6320225_16 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000455 254.0
HKD1_k127_6320225_17 aminopeptidase activity K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000000194 272.0
HKD1_k127_6320225_18 Transferrin receptor-like dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003971 274.0
HKD1_k127_6320225_19 PFAM Phage Tail Collar - - - 0.000000000000000000000000000000000000000000000000000000000000000000002409 238.0
HKD1_k127_6320225_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 525.0
HKD1_k127_6320225_20 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000009155 236.0
HKD1_k127_6320225_21 Phage Tail Collar Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002952 224.0
HKD1_k127_6320225_22 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000454 228.0
HKD1_k127_6320225_23 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000004476 226.0
HKD1_k127_6320225_24 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000001693 201.0
HKD1_k127_6320225_25 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000004116 185.0
HKD1_k127_6320225_26 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000000002256 175.0
HKD1_k127_6320225_27 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000003638 153.0
HKD1_k127_6320225_28 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000008335 141.0
HKD1_k127_6320225_29 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000779 151.0
HKD1_k127_6320225_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 488.0
HKD1_k127_6320225_30 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000007181 143.0
HKD1_k127_6320225_31 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000004665 116.0
HKD1_k127_6320225_33 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000004879 118.0
HKD1_k127_6320225_34 Protein of unknown function DUF58 - - - 0.00000000000000000000000000512 128.0
HKD1_k127_6320225_35 Ribosomal L32p protein family K02911 - - 0.000000000000000001257 87.0
HKD1_k127_6320225_36 Universal stress protein - - - 0.000000000000000002981 92.0
HKD1_k127_6320225_37 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000001337 91.0
HKD1_k127_6320225_38 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000001887 74.0
HKD1_k127_6320225_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 466.0
HKD1_k127_6320225_5 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 421.0
HKD1_k127_6320225_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 412.0
HKD1_k127_6320225_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 361.0
HKD1_k127_6320225_8 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 385.0
HKD1_k127_6320225_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 329.0
HKD1_k127_6352980_0 TIGRFAM amidohydrolase K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001554 286.0
HKD1_k127_6352980_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003762 263.0
HKD1_k127_6376719_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.042e-204 680.0
HKD1_k127_6376719_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 556.0
HKD1_k127_6376719_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 352.0
HKD1_k127_6376719_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 315.0
HKD1_k127_6376719_4 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 308.0
HKD1_k127_6376719_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000006709 214.0
HKD1_k127_6376719_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000001337 102.0
HKD1_k127_6376719_7 Tetratricopeptide repeat - - - 0.000000000000001134 89.0
HKD1_k127_6377101_0 DEAD/H associated K03724 - - 3.175e-232 763.0
HKD1_k127_6377101_1 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 529.0
HKD1_k127_6377101_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 518.0
HKD1_k127_6377101_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000007217 237.0
HKD1_k127_6377101_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000001227 187.0
HKD1_k127_6377101_5 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000005131 158.0
HKD1_k127_6377101_6 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000004075 116.0
HKD1_k127_6377101_7 Multidrug ABC transporter permease - - - 0.000000000000000000000000006225 118.0
HKD1_k127_6377101_8 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000002488 97.0
HKD1_k127_6377101_9 Bacterial membrane protein, YfhO - - - 0.000000002376 71.0
HKD1_k127_6377256_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1189.0
HKD1_k127_6377256_1 Radical SAM superfamily - - - 5.054e-204 659.0
HKD1_k127_6377256_2 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 443.0
HKD1_k127_6377256_3 PFAM major facilitator superfamily MFS_1 K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 292.0
HKD1_k127_6377256_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000162 203.0
HKD1_k127_6377256_5 FeS assembly SUF system protein SufT - - - 0.00000000000000000000000000000000000000000000000122 196.0
HKD1_k127_6377256_6 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000001716 112.0
HKD1_k127_6377256_7 - - - - 0.0000004033 59.0
HKD1_k127_6377256_8 amine dehydrogenase activity - - - 0.00002018 57.0
HKD1_k127_6400908_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 636.0
HKD1_k127_6400908_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 570.0
HKD1_k127_6400908_10 Belongs to the UbiD family - - - 0.0000000005872 71.0
HKD1_k127_6400908_2 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 421.0
HKD1_k127_6400908_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 349.0
HKD1_k127_6400908_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 307.0
HKD1_k127_6400908_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002882 273.0
HKD1_k127_6400908_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000002904 220.0
HKD1_k127_6400908_7 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000003685 219.0
HKD1_k127_6400908_8 EVE domain - - - 0.00000000000000000000000000000000001046 139.0
HKD1_k127_6400908_9 Transcriptional regulator K13643 - - 0.000000000001359 72.0
HKD1_k127_6451154_0 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000001504 176.0
HKD1_k127_6451154_1 methyltransferase activity K20444 - - 0.0000000000000000000000000000001525 141.0
HKD1_k127_6512755_0 Elongation factor G, domain IV K02355 - - 4.343e-201 647.0
HKD1_k127_6512755_1 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 583.0
HKD1_k127_6512755_10 Surface antigen variable number K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 391.0
HKD1_k127_6512755_11 Belongs to the ClpA ClpB family K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 347.0
HKD1_k127_6512755_12 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 336.0
HKD1_k127_6512755_13 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 326.0
HKD1_k127_6512755_14 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 304.0
HKD1_k127_6512755_15 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 319.0
HKD1_k127_6512755_16 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 285.0
HKD1_k127_6512755_17 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000003123 290.0
HKD1_k127_6512755_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000001149 272.0
HKD1_k127_6512755_19 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001174 286.0
HKD1_k127_6512755_2 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 532.0
HKD1_k127_6512755_20 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000234 258.0
HKD1_k127_6512755_21 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000008085 247.0
HKD1_k127_6512755_22 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000004008 213.0
HKD1_k127_6512755_23 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000003615 179.0
HKD1_k127_6512755_24 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000004243 168.0
HKD1_k127_6512755_25 YCII-related domain - - - 0.000000000000000000000000000000000000002636 163.0
HKD1_k127_6512755_26 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000003913 139.0
HKD1_k127_6512755_27 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.000000000000000000000000005559 122.0
HKD1_k127_6512755_28 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000236 109.0
HKD1_k127_6512755_29 PAS fold - - - 0.0000000000000000000005573 112.0
HKD1_k127_6512755_3 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 537.0
HKD1_k127_6512755_30 Arginine repressor, DNA binding domain K03402 - - 0.0000000000000000000017 100.0
HKD1_k127_6512755_31 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.00000000000000003996 96.0
HKD1_k127_6512755_32 Outer membrane protein (OmpH-like) K06142 - - 0.0000000001878 71.0
HKD1_k127_6512755_33 EamA-like transporter family - - - 0.0000000002485 72.0
HKD1_k127_6512755_34 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000001641 56.0
HKD1_k127_6512755_35 ABC-2 family transporter protein K01992 - - 0.0000003299 60.0
HKD1_k127_6512755_36 - - - - 0.000002048 56.0
HKD1_k127_6512755_37 DNA-templated transcription, initiation K03088 - - 0.000007753 57.0
HKD1_k127_6512755_38 - - - - 0.0002544 44.0
HKD1_k127_6512755_4 argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 520.0
HKD1_k127_6512755_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 473.0
HKD1_k127_6512755_6 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 458.0
HKD1_k127_6512755_7 sigma factor activity K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 457.0
HKD1_k127_6512755_8 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 414.0
HKD1_k127_6512755_9 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 416.0
HKD1_k127_6516618_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.594e-240 754.0
HKD1_k127_6516618_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 482.0
HKD1_k127_6516618_10 peptidase U62, modulator of DNA gyrase K03568 - - 0.000000000000000000000000001332 130.0
HKD1_k127_6516618_11 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000009353 111.0
HKD1_k127_6516618_12 4Fe-4S binding domain - - - 0.0000000000000000000000001862 123.0
HKD1_k127_6516618_13 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000009007 120.0
HKD1_k127_6516618_14 Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000002786 104.0
HKD1_k127_6516618_15 Thioredoxin-like domain - - - 0.000000000000000000476 100.0
HKD1_k127_6516618_16 protein kinase activity - - - 0.00000000000000002548 96.0
HKD1_k127_6516618_17 Biotin-requiring enzyme - - - 0.000000000000001553 85.0
HKD1_k127_6516618_18 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000004943 86.0
HKD1_k127_6516618_19 Phosphoserine phosphatase - - - 0.0000000001504 76.0
HKD1_k127_6516618_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 438.0
HKD1_k127_6516618_20 domain, Protein - - - 0.000000005333 67.0
HKD1_k127_6516618_21 guanyl-nucleotide exchange factor activity K20276 - - 0.00000001003 70.0
HKD1_k127_6516618_22 energy transducer activity K02487,K03832,K06596 - - 0.000001839 61.0
HKD1_k127_6516618_23 Belongs to the peptidase S8 family K14645 - - 0.00001278 57.0
HKD1_k127_6516618_24 Tetratricopeptide repeat - - - 0.0000594 56.0
HKD1_k127_6516618_25 - - - - 0.0002697 54.0
HKD1_k127_6516618_26 phosphorelay signal transduction system K07712 - - 0.0003798 44.0
HKD1_k127_6516618_3 3-oxoacid CoA-transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 332.0
HKD1_k127_6516618_4 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 332.0
HKD1_k127_6516618_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 311.0
HKD1_k127_6516618_6 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003548 304.0
HKD1_k127_6516618_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000001925 226.0
HKD1_k127_6516618_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.000000000000000000000000000000000000000000000000000000007701 209.0
HKD1_k127_6516618_9 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000008261 178.0
HKD1_k127_6564745_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1602.0
HKD1_k127_6564745_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 389.0
HKD1_k127_6564745_10 Beta-lactamase - - - 0.000000000000000009446 85.0
HKD1_k127_6564745_11 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000027 78.0
HKD1_k127_6564745_12 PFAM SMP-30 Gluconolaconase - - - 0.00000635 55.0
HKD1_k127_6564745_13 Sigma-70, region 4 K03088 - - 0.0002922 49.0
HKD1_k127_6564745_2 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001831 250.0
HKD1_k127_6564745_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000004691 263.0
HKD1_k127_6564745_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000001826 234.0
HKD1_k127_6564745_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000478 188.0
HKD1_k127_6564745_6 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000876 171.0
HKD1_k127_6564745_7 - - - - 0.000000000000000000000000000000000000001187 153.0
HKD1_k127_6564745_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000003433 151.0
HKD1_k127_6564745_9 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000287 121.0
HKD1_k127_6574927_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 2899.0
HKD1_k127_6574927_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.182e-240 778.0
HKD1_k127_6574927_10 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000005565 220.0
HKD1_k127_6574927_11 PFAM sugar transferase K13012 - - 0.000000000000000000000000000000000000000000000000000000296 213.0
HKD1_k127_6574927_12 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000223 171.0
HKD1_k127_6574927_13 permease K03548 - - 0.000000000000000000000000000000000000000722 163.0
HKD1_k127_6574927_14 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000007541 129.0
HKD1_k127_6574927_15 phosphorelay signal transduction system - - - 0.0000000000000000000000009538 111.0
HKD1_k127_6574927_16 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000005344 98.0
HKD1_k127_6574927_17 Glycosyl transferases group 1 K00786 - - 0.0000000000000001766 94.0
HKD1_k127_6574927_18 - - - - 0.000000000000001725 78.0
HKD1_k127_6574927_19 Protein conserved in bacteria - - - 0.0000000000002561 85.0
HKD1_k127_6574927_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 543.0
HKD1_k127_6574927_20 Protein conserved in bacteria - - - 0.000000000001337 82.0
HKD1_k127_6574927_21 - - - - 0.00000000001119 79.0
HKD1_k127_6574927_22 RDD family - - - 0.00000000001541 78.0
HKD1_k127_6574927_23 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000004856 70.0
HKD1_k127_6574927_24 COG1716 FOG FHA domain - - - 0.00000001181 68.0
HKD1_k127_6574927_25 Glycosyl transferase family group 2 - - - 0.00000008892 64.0
HKD1_k127_6574927_26 SMART Transport-associated and nodulation region K04065 - - 0.00006949 51.0
HKD1_k127_6574927_3 Sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 409.0
HKD1_k127_6574927_4 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 372.0
HKD1_k127_6574927_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001774 287.0
HKD1_k127_6574927_6 CHASE - - - 0.000000000000000000000000000000000000000000000000000000000000000001642 249.0
HKD1_k127_6574927_7 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000001794 231.0
HKD1_k127_6574927_8 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000006523 242.0
HKD1_k127_6574927_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000006014 217.0
HKD1_k127_6667026_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 341.0
HKD1_k127_6667026_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 355.0
HKD1_k127_6667026_10 Sporulation and spore germination - - - 0.00000000006739 72.0
HKD1_k127_6667026_11 - - - - 0.0000000007026 70.0
HKD1_k127_6667026_12 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000003593 61.0
HKD1_k127_6667026_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000004636 254.0
HKD1_k127_6667026_3 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.000000000000000000000000000000000000000000000000000000000000004721 237.0
HKD1_k127_6667026_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000005533 240.0
HKD1_k127_6667026_5 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000003105 192.0
HKD1_k127_6667026_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000001808 143.0
HKD1_k127_6667026_7 HemY domain protein - - - 0.000000000000000000000004954 118.0
HKD1_k127_6667026_8 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000001018 106.0
HKD1_k127_6667026_9 Alpha beta hydrolase - - - 0.000000000000000001321 100.0
HKD1_k127_6688220_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.609e-280 887.0
HKD1_k127_6688220_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.529e-266 864.0
HKD1_k127_6688220_10 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000004213 126.0
HKD1_k127_6688220_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000003473 102.0
HKD1_k127_6688220_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000261 68.0
HKD1_k127_6688220_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000004335 68.0
HKD1_k127_6688220_14 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000007388 58.0
HKD1_k127_6688220_15 hemolysin activation secretion protein - - - 0.00001975 55.0
HKD1_k127_6688220_16 Protein of unknown function (DUF507) K09804 - - 0.0004719 48.0
HKD1_k127_6688220_2 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 416.0
HKD1_k127_6688220_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 380.0
HKD1_k127_6688220_4 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000006996 244.0
HKD1_k127_6688220_5 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000002759 231.0
HKD1_k127_6688220_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000002987 220.0
HKD1_k127_6688220_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000006871 218.0
HKD1_k127_6688220_8 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000002025 183.0
HKD1_k127_6688220_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000002359 132.0
HKD1_k127_6696644_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 597.0
HKD1_k127_6696644_1 Short-chain dehydrogenase reductase sdr K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.0000000001243 62.0
HKD1_k127_6736831_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 563.0
HKD1_k127_6736831_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 368.0
HKD1_k127_6736831_10 DUF167 K09131 - - 0.0001167 56.0
HKD1_k127_6736831_2 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 306.0
HKD1_k127_6736831_3 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
HKD1_k127_6736831_4 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000001861 214.0
HKD1_k127_6736831_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000006971 201.0
HKD1_k127_6736831_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000193 205.0
HKD1_k127_6736831_7 DNA-binding transcription factor activity - - - 0.000000000000000000000000007299 116.0
HKD1_k127_6736831_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000000002275 90.0
HKD1_k127_6736831_9 - - - - 0.0000102 49.0
HKD1_k127_6788705_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 434.0
HKD1_k127_6788705_1 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 424.0
HKD1_k127_6788705_10 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000001287 119.0
HKD1_k127_6788705_11 to the N-terminal domain of Lon protease K07157 - - 0.00000000000000000000000000009923 124.0
HKD1_k127_6788705_12 Pentapeptide repeat K15352 - - 0.000000000000000002951 99.0
HKD1_k127_6788705_13 Domain of unknown function (DUF4340) - - - 0.0000000000000132 87.0
HKD1_k127_6788705_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 404.0
HKD1_k127_6788705_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 343.0
HKD1_k127_6788705_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 319.0
HKD1_k127_6788705_5 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000001685 235.0
HKD1_k127_6788705_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000003889 195.0
HKD1_k127_6788705_7 - - - - 0.000000000000000000000000000000000000000002257 178.0
HKD1_k127_6788705_8 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000001149 156.0
HKD1_k127_6788705_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000002378 147.0
HKD1_k127_6836582_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 312.0
HKD1_k127_6836582_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000001751 236.0
HKD1_k127_6836582_2 MOSC domain - - - 0.00000000000000000000000000000000000000000000001497 191.0
HKD1_k127_6836582_3 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000009969 183.0
HKD1_k127_691376_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 6.328e-210 676.0
HKD1_k127_691376_1 Transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 570.0
HKD1_k127_691376_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 526.0
HKD1_k127_691376_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 383.0
HKD1_k127_691376_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 374.0
HKD1_k127_691376_5 PFAM Aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 320.0
HKD1_k127_691376_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000003483 146.0
HKD1_k127_691376_7 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000007763 138.0
HKD1_k127_691376_8 - - - - 0.00000000000000000000000000002379 132.0
HKD1_k127_691376_9 lyase activity - - - 0.00000000009428 74.0
HKD1_k127_6971147_0 choline dehydrogenase activity - - - 4.048e-267 830.0
HKD1_k127_6971147_1 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 615.0
HKD1_k127_6971147_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001421 190.0
HKD1_k127_6971147_11 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000002007 186.0
HKD1_k127_6971147_12 DoxX K15977 - - 0.000000000000000000000000000000000000009791 151.0
HKD1_k127_6971147_13 pyridoxamine 5-phosphate - - - 0.00000000000000000000003807 105.0
HKD1_k127_6971147_14 Putative zinc-finger - - - 0.0000000002658 70.0
HKD1_k127_6971147_15 Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000007245 63.0
HKD1_k127_6971147_16 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000009123 59.0
HKD1_k127_6971147_2 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 526.0
HKD1_k127_6971147_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 392.0
HKD1_k127_6971147_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 370.0
HKD1_k127_6971147_5 virion core protein, lumpy skin disease virus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 357.0
HKD1_k127_6971147_6 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
HKD1_k127_6971147_7 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005654 276.0
HKD1_k127_6971147_8 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001214 255.0
HKD1_k127_6971147_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000001028 216.0
HKD1_k127_7045204_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 623.0
HKD1_k127_7045204_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 503.0
HKD1_k127_7045204_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 377.0
HKD1_k127_7045204_3 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 302.0
HKD1_k127_7045204_4 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000103 175.0
HKD1_k127_7045204_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000004548 155.0
HKD1_k127_7050037_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 589.0
HKD1_k127_7050037_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 411.0
HKD1_k127_7050037_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000003074 171.0
HKD1_k127_7050037_11 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000005726 169.0
HKD1_k127_7050037_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000004073 145.0
HKD1_k127_7050037_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000005221 119.0
HKD1_k127_7050037_14 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00004089 48.0
HKD1_k127_7050037_15 PFAM aminoacyl-tRNA synthetase class Ib K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0001393 44.0
HKD1_k127_7050037_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 352.0
HKD1_k127_7050037_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000001314 256.0
HKD1_k127_7050037_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000001531 224.0
HKD1_k127_7050037_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000001087 231.0
HKD1_k127_7050037_6 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000002774 216.0
HKD1_k127_7050037_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000001097 204.0
HKD1_k127_7050037_8 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000004516 198.0
HKD1_k127_7050037_9 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000009099 187.0
HKD1_k127_7055809_0 Polyphosphate kinase 2 (PPK2) - - - 2.72e-209 661.0
HKD1_k127_7055809_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 560.0
HKD1_k127_7055809_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 480.0
HKD1_k127_7055809_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 344.0
HKD1_k127_7055809_4 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 360.0
HKD1_k127_7055809_5 acyl-CoA dehydrogenase - - - 0.000000000000000000000000007609 113.0
HKD1_k127_7097390_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1226.0
HKD1_k127_7097390_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 604.0
HKD1_k127_7097390_10 polysaccharide deacetylase - - - 0.0000000000000000001894 103.0
HKD1_k127_7097390_2 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 458.0
HKD1_k127_7097390_3 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 376.0
HKD1_k127_7097390_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 376.0
HKD1_k127_7097390_5 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000000003084 246.0
HKD1_k127_7097390_6 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000009426 183.0
HKD1_k127_7097390_7 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000003539 156.0
HKD1_k127_7097390_8 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000001273 141.0
HKD1_k127_7097390_9 long-chain fatty acid transport protein - - - 0.00000000000000000000009 108.0
HKD1_k127_7109157_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 561.0
HKD1_k127_7109157_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 472.0
HKD1_k127_7109157_10 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000003817 208.0
HKD1_k127_7109157_11 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000005768 216.0
HKD1_k127_7109157_12 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000005347 194.0
HKD1_k127_7109157_13 Hep Hag repeat protein K09942,K21449 - - 0.0000000000000000000000000000000000000000006234 180.0
HKD1_k127_7109157_14 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000007227 146.0
HKD1_k127_7109157_15 serine threonine protein kinase - - - 0.00000000000000000000000004838 125.0
HKD1_k127_7109157_16 polysaccharide deacetylase - - - 0.00000000002845 77.0
HKD1_k127_7109157_17 - - - - 0.00000008886 58.0
HKD1_k127_7109157_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 416.0
HKD1_k127_7109157_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 422.0
HKD1_k127_7109157_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 304.0
HKD1_k127_7109157_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 312.0
HKD1_k127_7109157_6 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005266 278.0
HKD1_k127_7109157_7 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000005351 263.0
HKD1_k127_7109157_8 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000001899 259.0
HKD1_k127_7109157_9 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000001468 233.0
HKD1_k127_7112777_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 574.0
HKD1_k127_7112777_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000001461 226.0
HKD1_k127_7112777_2 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000004177 206.0
HKD1_k127_7112777_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000002598 184.0
HKD1_k127_7112777_4 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000001973 120.0
HKD1_k127_7112777_5 - - - - 0.0000000008509 71.0
HKD1_k127_7123719_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.409e-208 656.0
HKD1_k127_7123719_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000105 225.0
HKD1_k127_7123719_2 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000000000000002945 191.0
HKD1_k127_7125513_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 7.337e-217 694.0
HKD1_k127_7125513_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.65e-211 676.0
HKD1_k127_7125513_10 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000312 231.0
HKD1_k127_7125513_11 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000009231 222.0
HKD1_k127_7125513_12 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000007434 228.0
HKD1_k127_7125513_13 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000001103 160.0
HKD1_k127_7125513_14 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000006606 155.0
HKD1_k127_7125513_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.00000000000000000000000000000001088 144.0
HKD1_k127_7125513_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000151 111.0
HKD1_k127_7125513_17 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000001669 66.0
HKD1_k127_7125513_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 612.0
HKD1_k127_7125513_3 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 597.0
HKD1_k127_7125513_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 427.0
HKD1_k127_7125513_5 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 410.0
HKD1_k127_7125513_6 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001692 278.0
HKD1_k127_7125513_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001339 267.0
HKD1_k127_7125513_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 250.0
HKD1_k127_7125513_9 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000009091 246.0
HKD1_k127_7140910_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.223e-267 847.0
HKD1_k127_7140910_1 copper-translocating P-type ATPase K17686 - 3.6.3.54 5.376e-252 807.0
HKD1_k127_7140910_10 Domain of unknown function (DUF4412) - - - 0.000000000000000000000000000000000000000000008775 172.0
HKD1_k127_7140910_12 phosphoserine phosphatase activity K07052,K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000001477 183.0
HKD1_k127_7140910_13 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 - 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000004056 139.0
HKD1_k127_7140910_14 - - - - 0.0000000000000000000000000000008115 133.0
HKD1_k127_7140910_15 - - - - 0.0000000000000000002 95.0
HKD1_k127_7140910_16 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000005735 79.0
HKD1_k127_7140910_17 - - - - 0.00000000004708 74.0
HKD1_k127_7140910_2 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 505.0
HKD1_k127_7140910_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 485.0
HKD1_k127_7140910_4 ABC transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 489.0
HKD1_k127_7140910_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 344.0
HKD1_k127_7140910_6 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 320.0
HKD1_k127_7140910_7 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 336.0
HKD1_k127_7140910_8 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003026 288.0
HKD1_k127_7140910_9 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000003175 239.0
HKD1_k127_7156039_0 ABC transporter transmembrane K11085 - - 1.154e-258 833.0
HKD1_k127_7156039_1 Amino acid permease - - - 1.942e-229 728.0
HKD1_k127_7156039_10 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 374.0
HKD1_k127_7156039_11 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
HKD1_k127_7156039_12 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 361.0
HKD1_k127_7156039_13 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 349.0
HKD1_k127_7156039_14 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 359.0
HKD1_k127_7156039_15 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 353.0
HKD1_k127_7156039_16 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 345.0
HKD1_k127_7156039_17 Binding-protein-dependent transport system inner membrane component K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 352.0
HKD1_k127_7156039_18 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 346.0
HKD1_k127_7156039_19 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 306.0
HKD1_k127_7156039_2 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 501.0
HKD1_k127_7156039_20 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02017,K02045,K15497 - 3.6.3.25,3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002069 293.0
HKD1_k127_7156039_21 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001163 274.0
HKD1_k127_7156039_22 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003864 286.0
HKD1_k127_7156039_24 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000007988 234.0
HKD1_k127_7156039_25 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001102 244.0
HKD1_k127_7156039_26 ABC transporter, phosphonate, periplasmic substrate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000002732 226.0
HKD1_k127_7156039_27 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000009861 227.0
HKD1_k127_7156039_28 E1-E2 ATPase K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000001328 199.0
HKD1_k127_7156039_29 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000004366 197.0
HKD1_k127_7156039_3 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 503.0
HKD1_k127_7156039_30 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000001421 198.0
HKD1_k127_7156039_31 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000007648 194.0
HKD1_k127_7156039_32 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000002516 190.0
HKD1_k127_7156039_33 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000968 180.0
HKD1_k127_7156039_34 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000001567 139.0
HKD1_k127_7156039_35 pfam nudix - - - 0.000000000000000000000000000000002932 135.0
HKD1_k127_7156039_36 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000102 125.0
HKD1_k127_7156039_37 RNA recognition motif - - - 0.000000000000000000000000001004 115.0
HKD1_k127_7156039_38 Putative DNA-binding domain - - - 0.000000000000000000000000006836 121.0
HKD1_k127_7156039_39 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000005153 105.0
HKD1_k127_7156039_4 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 480.0
HKD1_k127_7156039_40 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000001867 98.0
HKD1_k127_7156039_41 Phospholipid methyltransferase - - - 0.0000000000000000000003591 102.0
HKD1_k127_7156039_43 Membrane - - - 0.000000000000001093 93.0
HKD1_k127_7156039_45 - - - - 0.00000000000001597 78.0
HKD1_k127_7156039_46 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000001986 83.0
HKD1_k127_7156039_47 Membrane - - - 0.0000000000004264 83.0
HKD1_k127_7156039_48 ACT domain - - - 0.0000000000156 71.0
HKD1_k127_7156039_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 457.0
HKD1_k127_7156039_50 protein-disulfide reductase activity K01829,K04084 - 1.8.1.8,5.3.4.1 0.000000003883 70.0
HKD1_k127_7156039_6 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 445.0
HKD1_k127_7156039_7 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 439.0
HKD1_k127_7156039_8 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 430.0
HKD1_k127_7156039_9 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 443.0
HKD1_k127_7160228_0 ABC transporter related K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000001721 237.0
HKD1_k127_7160228_1 PFAM ABC-2 type transporter K01992,K09690 - - 0.00000000000000000000000000000000000000000006329 173.0
HKD1_k127_7160228_2 - - - - 0.00000000000001721 79.0
HKD1_k127_7160228_3 PFAM Methyltransferase type 11 K03892 - - 0.00000003408 67.0
HKD1_k127_7160228_4 PFAM glycosyl transferase group 1 - - - 0.0000001203 61.0
HKD1_k127_7202602_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 603.0
HKD1_k127_7202602_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 469.0
HKD1_k127_7202602_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 488.0
HKD1_k127_7202602_3 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 331.0
HKD1_k127_7202602_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000002356 154.0
HKD1_k127_7202602_5 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000769 100.0
HKD1_k127_7219822_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 1.55e-201 665.0
HKD1_k127_7219822_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000003801 236.0
HKD1_k127_7219822_10 polysaccharide deacetylase - - - 0.000000000002565 80.0
HKD1_k127_7219822_11 amine dehydrogenase activity - - - 0.0002932 45.0
HKD1_k127_7219822_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000406 213.0
HKD1_k127_7219822_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000008149 168.0
HKD1_k127_7219822_4 ECF sigma factor - - - 0.00000000000000000000000000000000000000003914 159.0
HKD1_k127_7219822_5 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.000000000000000000000000000000000002731 149.0
HKD1_k127_7219822_6 - - - - 0.0000000000000009919 92.0
HKD1_k127_7219822_7 Protein tyrosine kinase - - - 0.00000000000001171 86.0
HKD1_k127_7219822_8 - - - - 0.00000000000001416 89.0
HKD1_k127_7219822_9 - - - - 0.0000000000005853 83.0
HKD1_k127_7264847_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 426.0
HKD1_k127_7264847_1 Protein of unknown function - - - 0.00000000000000000000000000001444 136.0
HKD1_k127_7264847_2 Protein of unknown function K09800 - - 0.0000000000000000000000000382 125.0
HKD1_k127_7264847_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000001543 83.0
HKD1_k127_7264847_4 - - - - 0.000006211 52.0
HKD1_k127_7317358_0 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 491.0
HKD1_k127_7317358_1 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000002548 199.0
HKD1_k127_7317358_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis - - - 0.0000000000000000000000000001766 129.0
HKD1_k127_7317358_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000002536 123.0
HKD1_k127_7317358_4 - - - - 0.0000000000000000000003691 106.0
HKD1_k127_7317358_5 - - - - 0.0000000000000001566 87.0
HKD1_k127_7324334_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000001325 220.0
HKD1_k127_7324334_1 Glycosyltransferase like family 2 - - - 0.00000000000000000005488 101.0
HKD1_k127_7326368_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 299.0
HKD1_k127_7326368_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000004868 251.0
HKD1_k127_7326368_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000742 228.0
HKD1_k127_7326368_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000003426 195.0
HKD1_k127_7326368_5 Protein of unknown function (DUF420) - - - 0.000000000000000000000000000000000005091 154.0
HKD1_k127_7326368_6 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000001565 132.0
HKD1_k127_7326368_7 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000059 128.0
HKD1_k127_7326368_8 Hpt domain - - - 0.0000000000000000000006693 111.0
HKD1_k127_7330108_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 437.0
HKD1_k127_7330108_1 CoA-transferase activity K01027,K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 330.0
HKD1_k127_7330108_2 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
HKD1_k127_7330108_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133,5.1.3.13 0.000000000000000000000000000000000000000000000000000000008086 213.0
HKD1_k127_7330108_4 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000004089 176.0
HKD1_k127_7330108_5 Belongs to the peptidase S8 family K14645 - - 0.00000008844 64.0
HKD1_k127_7330108_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000001356 51.0
HKD1_k127_7346143_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 468.0
HKD1_k127_7346143_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000166 164.0
HKD1_k127_7346143_2 domain, Protein - - - 0.000000000000000000000000001317 130.0
HKD1_k127_7346143_3 cheY-homologous receiver domain - - - 0.000000000000004472 77.0
HKD1_k127_7346143_4 protein phosphatase 2C domain protein - - - 0.000000009717 64.0
HKD1_k127_7364202_0 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 423.0
HKD1_k127_7364202_1 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 316.0
HKD1_k127_7364202_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000001527 198.0
HKD1_k127_7364202_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000003447 170.0
HKD1_k127_7364202_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000006159 164.0
HKD1_k127_7364202_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 0.000000000000000000000000000000000002329 147.0
HKD1_k127_7364202_6 - - - - 0.000000000000000000000000000000000003763 141.0
HKD1_k127_7364202_7 Forkhead associated domain - - - 0.000000000008082 76.0
HKD1_k127_7364202_8 - - - - 0.00000000001814 78.0
HKD1_k127_7364202_9 oxidoreductase activity K07114 - - 0.0002465 55.0
HKD1_k127_7365107_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 337.0
HKD1_k127_7365107_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000006901 216.0
HKD1_k127_7365107_2 Pfam Glycosyl transferase family 2 - - - 0.000000001663 70.0
HKD1_k127_7366616_0 Glycogen debranching enzyme - - - 0.0 1460.0
HKD1_k127_7366616_1 Glycogen debranching enzyme - - - 0.0 1384.0
HKD1_k127_7366616_10 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 445.0
HKD1_k127_7366616_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 450.0
HKD1_k127_7366616_12 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 384.0
HKD1_k127_7366616_13 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 361.0
HKD1_k127_7366616_14 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 362.0
HKD1_k127_7366616_15 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 337.0
HKD1_k127_7366616_16 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 325.0
HKD1_k127_7366616_17 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 323.0
HKD1_k127_7366616_18 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 289.0
HKD1_k127_7366616_19 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002 280.0
HKD1_k127_7366616_2 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1286.0
HKD1_k127_7366616_20 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000008146 247.0
HKD1_k127_7366616_21 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000005433 229.0
HKD1_k127_7366616_22 ferric iron binding K02380 - - 0.00000000000000000000000000000000000000000000000000000003237 224.0
HKD1_k127_7366616_23 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000002227 204.0
HKD1_k127_7366616_24 protein secretion K15125 - - 0.00000000000000000000000000000000000000000005734 184.0
HKD1_k127_7366616_25 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000005354 142.0
HKD1_k127_7366616_26 - - - - 0.000000000000003244 90.0
HKD1_k127_7366616_27 Glyoxalase-like domain - - - 0.00000000003041 70.0
HKD1_k127_7366616_28 - K01992,K19341 - - 0.00003664 51.0
HKD1_k127_7366616_3 Polysulphide reductase, NrfD K00124 - - 1.436e-318 1002.0
HKD1_k127_7366616_4 Sulfate permease family - - - 6.842e-226 713.0
HKD1_k127_7366616_5 Fumarase C C-terminus K01744 - 4.3.1.1 3.807e-207 653.0
HKD1_k127_7366616_6 Predicted Permease Membrane Region K07085 - - 1.58e-204 650.0
HKD1_k127_7366616_7 Alpha amylase, catalytic domain - - - 7.559e-204 681.0
HKD1_k127_7366616_8 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 520.0
HKD1_k127_7366616_9 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 532.0
HKD1_k127_742666_0 Belongs to the peptidase M16 family K07263 - - 0.0 1057.0
HKD1_k127_742666_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.142e-257 824.0
HKD1_k127_742666_10 chlorophyll binding - - - 0.000000000000000000000000000000000000000001266 164.0
HKD1_k127_742666_11 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000005854 164.0
HKD1_k127_742666_12 Protein conserved in bacteria - - - 0.000000000000000000000000000000000005233 141.0
HKD1_k127_742666_13 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000003116 107.0
HKD1_k127_742666_14 Protein of unknown function, DUF481 K07283 - - 0.000000000000009052 85.0
HKD1_k127_742666_15 SCO1 SenC K07152 - - 0.0000000000008548 81.0
HKD1_k127_742666_16 Redoxin - - - 0.0000000642 61.0
HKD1_k127_742666_2 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 616.0
HKD1_k127_742666_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 566.0
HKD1_k127_742666_4 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 360.0
HKD1_k127_742666_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 317.0
HKD1_k127_742666_6 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000256 251.0
HKD1_k127_742666_7 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008999 271.0
HKD1_k127_742666_8 Cytochrome c oxidase subunit K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000004328 225.0
HKD1_k127_742666_9 Cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000113 186.0
HKD1_k127_7452132_0 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 362.0
HKD1_k127_7452132_1 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000133 170.0
HKD1_k127_7452132_2 Doxx family K15977 - - 0.00000000000000000000000000000000006598 153.0
HKD1_k127_7452132_3 PFAM Ion transport 2 domain protein - - - 0.000000000000000000001173 101.0
HKD1_k127_7486732_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1330.0
HKD1_k127_7486732_1 topoisomerase K02469 - 5.99.1.3 1.492e-270 853.0
HKD1_k127_7486732_10 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 295.0
HKD1_k127_7486732_11 selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002035 252.0
HKD1_k127_7486732_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000003685 252.0
HKD1_k127_7486732_13 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000001904 224.0
HKD1_k127_7486732_14 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000007511 181.0
HKD1_k127_7486732_15 homoserine K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000001571 179.0
HKD1_k127_7486732_16 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000007506 170.0
HKD1_k127_7486732_17 von Willebrand factor, type A - - - 0.000000000000000000000000000000002153 151.0
HKD1_k127_7486732_18 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000005161 132.0
HKD1_k127_7486732_19 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000001243 127.0
HKD1_k127_7486732_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 511.0
HKD1_k127_7486732_20 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000008428 124.0
HKD1_k127_7486732_21 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000002767 108.0
HKD1_k127_7486732_22 Pas domain - - - 0.000000000000000001274 95.0
HKD1_k127_7486732_23 Helix-hairpin-helix motif K02237 - - 0.000000000000003073 85.0
HKD1_k127_7486732_24 Peptidase M56 - - - 0.00000000000001924 88.0
HKD1_k127_7486732_25 Peptidase family M23 - - - 0.00000000000004591 85.0
HKD1_k127_7486732_26 Anti-sigma-K factor rskA - - - 0.00000000001855 74.0
HKD1_k127_7486732_27 Response regulator receiver - - - 0.0000000007689 66.0
HKD1_k127_7486732_28 Rieske [2Fe-2S] domain - - - 0.00000009961 65.0
HKD1_k127_7486732_29 LTXXQ motif family protein K06006 - - 0.000002466 57.0
HKD1_k127_7486732_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 473.0
HKD1_k127_7486732_30 COG1290 Cytochrome b subunit of the bc complex - - - 0.000005668 59.0
HKD1_k127_7486732_31 O-Antigen ligase - - - 0.00009896 57.0
HKD1_k127_7486732_32 O-Antigen ligase - - - 0.0003846 55.0
HKD1_k127_7486732_33 deoxyhypusine monooxygenase activity - - - 0.0007084 52.0
HKD1_k127_7486732_4 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 458.0
HKD1_k127_7486732_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 371.0
HKD1_k127_7486732_6 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 369.0
HKD1_k127_7486732_7 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 367.0
HKD1_k127_7486732_8 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 346.0
HKD1_k127_7486732_9 Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 324.0
HKD1_k127_7527460_0 WD-40 repeat K20332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 348.0
HKD1_k127_7527460_1 ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 319.0
HKD1_k127_7527460_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 312.0
HKD1_k127_7527460_3 PFAM ABC transporter related K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003613 286.0
HKD1_k127_7527460_4 glycine betaine transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005706 257.0
HKD1_k127_7527460_5 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K20333 - - 0.0000000000000000000000000000000000000000000000000000000000000002404 230.0
HKD1_k127_7553479_0 AcrB/AcrD/AcrF family K03296,K18138 - - 4.618e-263 826.0
HKD1_k127_7553479_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 572.0
HKD1_k127_7553479_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 497.0
HKD1_k127_7553479_3 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 361.0
HKD1_k127_7553479_4 Ferrous iron transport protein B K04759 - - 0.00000000000000000003086 90.0
HKD1_k127_7553479_5 response to abiotic stimulus K06867 - - 0.00000000000000000006341 98.0
HKD1_k127_7574236_0 Peptidase family M3 K01284,K01414 - 3.4.15.5,3.4.24.70 4.546e-253 800.0
HKD1_k127_7574236_1 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 381.0
HKD1_k127_7574236_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 340.0
HKD1_k127_7574236_3 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000002074 219.0
HKD1_k127_7574236_4 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000001787 93.0
HKD1_k127_7574236_5 glycosyl transferase family 39 K00721 - 2.4.1.83 0.000001415 62.0
HKD1_k127_7588299_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1071.0
HKD1_k127_7588299_1 ThiF family K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 437.0
HKD1_k127_7588299_10 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000004786 181.0
HKD1_k127_7588299_11 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000001271 134.0
HKD1_k127_7588299_13 Winged helix-turn-helix transcription repressor, HrcA DNA-binding - - - 0.00000000000000000000001388 105.0
HKD1_k127_7588299_14 Predicted membrane protein (DUF2339) - - - 0.000000000000000005049 91.0
HKD1_k127_7588299_15 FHA domain - - - 0.0000000000171 71.0
HKD1_k127_7588299_2 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 345.0
HKD1_k127_7588299_3 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 336.0
HKD1_k127_7588299_4 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 314.0
HKD1_k127_7588299_5 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 308.0
HKD1_k127_7588299_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001257 308.0
HKD1_k127_7588299_7 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000001561 246.0
HKD1_k127_7588299_8 Serine threonine protein kinase K07282,K12132,K15539 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000497 237.0
HKD1_k127_7588299_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000698 218.0
HKD1_k127_7625976_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 593.0
HKD1_k127_7625976_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 546.0
HKD1_k127_7625976_2 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 294.0
HKD1_k127_7625976_3 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008038 303.0
HKD1_k127_7625976_4 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000009599 209.0
HKD1_k127_7625976_5 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003309 173.0
HKD1_k127_7625976_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000003155 132.0
HKD1_k127_7625976_7 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000003286 124.0
HKD1_k127_7672215_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 599.0
HKD1_k127_7672215_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 472.0
HKD1_k127_7672215_10 - - - - 0.000000000000000000000003323 111.0
HKD1_k127_7672215_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 371.0
HKD1_k127_7672215_3 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 394.0
HKD1_k127_7672215_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 368.0
HKD1_k127_7672215_5 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000005306 198.0
HKD1_k127_7672215_6 - - - - 0.00000000000000000000000000000000000000000000206 189.0
HKD1_k127_7672215_7 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000009353 147.0
HKD1_k127_7672215_8 DinB family - - - 0.00000000000000000000000000000000000237 156.0
HKD1_k127_7672215_9 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000005435 124.0
HKD1_k127_77868_0 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 602.0
HKD1_k127_77868_1 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000009479 228.0
HKD1_k127_77868_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000001326 217.0
HKD1_k127_77868_3 Cytidylate kinase-like family - - - 0.00000000000000000000000000000159 130.0
HKD1_k127_77868_4 AAA ATPase domain - - - 0.00000000000000002967 97.0
HKD1_k127_77868_5 Vegetative incompatibility protein het-e-1 - - - 0.00000006935 66.0
HKD1_k127_7826545_0 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 521.0
HKD1_k127_7826545_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 403.0
HKD1_k127_7826545_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000002892 164.0
HKD1_k127_7826545_3 lipolytic protein G-D-S-L family - - - 0.000000000000000006256 97.0
HKD1_k127_7899308_0 Dehydrogenase E1 component K11381 - 1.2.4.4 4.302e-312 969.0
HKD1_k127_7899308_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 6.842e-289 903.0
HKD1_k127_7899308_10 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 363.0
HKD1_k127_7899308_11 PS-10 peptidase S37 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 361.0
HKD1_k127_7899308_12 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 351.0
HKD1_k127_7899308_13 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 330.0
HKD1_k127_7899308_14 Glutaminase K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 329.0
HKD1_k127_7899308_15 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HKD1_k127_7899308_16 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002394 295.0
HKD1_k127_7899308_17 TonB-dependent Receptor Plug Domain K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000004153 248.0
HKD1_k127_7899308_18 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
HKD1_k127_7899308_19 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000002421 214.0
HKD1_k127_7899308_2 Penicillin amidase K01434 - 3.5.1.11 3.593e-275 878.0
HKD1_k127_7899308_20 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000009799 189.0
HKD1_k127_7899308_21 - - - - 0.0000000000000000000000000000000000000000000004953 169.0
HKD1_k127_7899308_23 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000001007 185.0
HKD1_k127_7899308_24 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000003276 161.0
HKD1_k127_7899308_25 - - - - 0.00000000000000000000000000000000000000007405 168.0
HKD1_k127_7899308_26 Low affinity iron permease - - - 0.0000000000000000000000000000000000000003112 164.0
HKD1_k127_7899308_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.0000000000000000000000000000000000003662 154.0
HKD1_k127_7899308_28 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000005656 139.0
HKD1_k127_7899308_29 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000001382 130.0
HKD1_k127_7899308_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 5.417e-207 657.0
HKD1_k127_7899308_30 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000002649 128.0
HKD1_k127_7899308_31 Membrane - - - 0.000000000000000000001228 108.0
HKD1_k127_7899308_32 Domain of unknown function (DUF4136) - - - 0.00000000000000000009447 96.0
HKD1_k127_7899308_33 - - - - 0.00000000000000000604 91.0
HKD1_k127_7899308_34 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000001318 94.0
HKD1_k127_7899308_35 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000004069 86.0
HKD1_k127_7899308_36 - - - - 0.0000000009889 70.0
HKD1_k127_7899308_4 COG NOG10142 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 540.0
HKD1_k127_7899308_5 cell wall organization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 531.0
HKD1_k127_7899308_6 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 499.0
HKD1_k127_7899308_7 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 512.0
HKD1_k127_7899308_8 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 486.0
HKD1_k127_7899308_9 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 393.0
HKD1_k127_7950226_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 527.0
HKD1_k127_7950226_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000004167 103.0
HKD1_k127_7979994_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 333.0
HKD1_k127_7979994_1 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 322.0
HKD1_k127_7979994_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001407 275.0
HKD1_k127_7979994_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000003846 143.0
HKD1_k127_7979994_4 DUF167 K09131 - - 0.000000000000000000000000000000001513 140.0
HKD1_k127_7979994_5 - - - - 0.0000000000000000000000000663 120.0
HKD1_k127_7984435_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.412e-270 859.0
HKD1_k127_7984435_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 6.713e-264 835.0
HKD1_k127_7984435_10 Universal stress protein - - - 0.0002362 49.0
HKD1_k127_7984435_2 Ferrous iron transport protein B K04759 - - 3.084e-262 831.0
HKD1_k127_7984435_3 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 387.0
HKD1_k127_7984435_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 336.0
HKD1_k127_7984435_5 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 306.0
HKD1_k127_7984435_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 288.0
HKD1_k127_7984435_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000008798 165.0
HKD1_k127_7984435_8 response to abiotic stimulus K06867 - - 0.0000000000000000007583 102.0
HKD1_k127_7984435_9 FeoA K04758 - - 0.000000000000000002238 87.0
HKD1_k127_811017_0 AAA ATPase domain - - - 0.0 1052.0
HKD1_k127_811017_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 462.0
HKD1_k127_811017_10 Ami_2 - - - 0.00002725 57.0
HKD1_k127_811017_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 424.0
HKD1_k127_811017_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 403.0
HKD1_k127_811017_4 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 344.0
HKD1_k127_811017_5 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 314.0
HKD1_k127_811017_6 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001332 263.0
HKD1_k127_811017_7 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000002165 225.0
HKD1_k127_811017_8 PFAM Peptidase M11 gametolysin - - - 0.00000000000000000000000000000000000000000004688 181.0
HKD1_k127_811017_9 - - - - 0.000007161 59.0
HKD1_k127_811743_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.666e-246 794.0
HKD1_k127_811743_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 615.0
HKD1_k127_811743_10 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000001882 240.0
HKD1_k127_811743_11 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000001228 239.0
HKD1_k127_811743_12 COG0147 Anthranilate para-aminobenzoate synthases component I K01665,K13950 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000001079 235.0
HKD1_k127_811743_13 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000008018 214.0
HKD1_k127_811743_14 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000379 201.0
HKD1_k127_811743_15 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000001517 209.0
HKD1_k127_811743_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000004995 196.0
HKD1_k127_811743_17 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000003248 183.0
HKD1_k127_811743_18 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000002005 185.0
HKD1_k127_811743_19 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000005723 169.0
HKD1_k127_811743_2 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 481.0
HKD1_k127_811743_20 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000001143 154.0
HKD1_k127_811743_21 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000002927 119.0
HKD1_k127_811743_22 Outer membrane lipoprotein - - - 0.0000000000000000000000003196 120.0
HKD1_k127_811743_23 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000007248 123.0
HKD1_k127_811743_24 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000001588 110.0
HKD1_k127_811743_25 Sigma-70 region 2 K03088 - - 0.000000000000000000001078 102.0
HKD1_k127_811743_26 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.000000000000000002881 94.0
HKD1_k127_811743_28 Lipopolysaccharide-assembly - - - 0.0000000000000006208 92.0
HKD1_k127_811743_29 - - - - 0.000000000000001326 88.0
HKD1_k127_811743_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 378.0
HKD1_k127_811743_30 Binds directly to 16S ribosomal RNA K02968 - - 0.00000236 59.0
HKD1_k127_811743_31 TIGRFAM TonB family K03832 - - 0.00001031 57.0
HKD1_k127_811743_4 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 351.0
HKD1_k127_811743_5 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 313.0
HKD1_k127_811743_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001881 305.0
HKD1_k127_811743_7 Phage shock protein A, PspA K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
HKD1_k127_811743_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000121 276.0
HKD1_k127_811743_9 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001673 259.0
HKD1_k127_857562_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 280.0
HKD1_k127_857562_1 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000001127 233.0
HKD1_k127_857562_2 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000003307 230.0
HKD1_k127_857562_3 Cupin domain - - - 0.00000000000000000000000000000000000000001311 166.0
HKD1_k127_857562_4 - - - - 0.0000000000000000000000000000000005835 138.0
HKD1_k127_857562_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K20276 - - 0.0000000004001 73.0
HKD1_k127_927548_0 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 301.0
HKD1_k127_927548_1 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
HKD1_k127_927548_2 ABC-type multidrug transport system ATPase K01990 - - 0.000000000000000000000000000000000000000002124 169.0
HKD1_k127_927548_3 - - - - 0.00000000000000000005326 103.0
HKD1_k127_927548_4 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000001824 93.0
HKD1_k127_927548_5 FR47-like protein - - - 0.000000000001898 68.0