Overview

ID MAG01765
Name HKD1_bin.85
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Rariloculales
Family Rariloculaceae
Genus FEN-1219
Species
Assembly information
Completeness (%) 88.45
Contamination (%) 6.33
GC content (%) 68.0
N50 (bp) 28,365
Genome size (bp) 3,915,525

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3427

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1005422_0 TonB dependent receptor - - - 3.995e-225 714.0
HKD1_k127_1005422_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 376.0
HKD1_k127_1005422_10 NmrA-like family K19267 - 1.6.5.2 0.00000003844 55.0
HKD1_k127_1005422_11 CAAX protease self-immunity - - - 0.0006831 50.0
HKD1_k127_1005422_2 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 321.0
HKD1_k127_1005422_3 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002828 280.0
HKD1_k127_1005422_4 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000004295 203.0
HKD1_k127_1005422_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000035 195.0
HKD1_k127_1005422_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000000000436 179.0
HKD1_k127_1005422_7 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000000000003892 162.0
HKD1_k127_1005422_8 Anp1 - - - 0.00000000000000000000000001893 123.0
HKD1_k127_101064_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 515.0
HKD1_k127_101064_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 463.0
HKD1_k127_101064_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000008506 200.0
HKD1_k127_101064_11 STAS-like domain of unknown function (DUF4325) - - - 0.000000000000000000000000000000000000001099 154.0
HKD1_k127_101064_12 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000001138 154.0
HKD1_k127_101064_13 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000171 139.0
HKD1_k127_101064_14 SnoaL-like domain - - - 0.000000000000000000000000000000002577 132.0
HKD1_k127_101064_15 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000008526 120.0
HKD1_k127_101064_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 407.0
HKD1_k127_101064_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 370.0
HKD1_k127_101064_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 311.0
HKD1_k127_101064_5 PhoPQ-activated pathogenicity-related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 302.0
HKD1_k127_101064_6 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000185 288.0
HKD1_k127_101064_7 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002202 258.0
HKD1_k127_101064_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000001013 218.0
HKD1_k127_101064_9 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000004869 214.0
HKD1_k127_107095_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 3.482e-288 919.0
HKD1_k127_107095_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.91e-282 889.0
HKD1_k127_107095_10 PFAM GPR1 FUN34 yaaH family protein K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008754 276.0
HKD1_k127_107095_11 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000007638 210.0
HKD1_k127_107095_12 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000001239 156.0
HKD1_k127_107095_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000001423 129.0
HKD1_k127_107095_14 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000003197 97.0
HKD1_k127_107095_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.819e-244 769.0
HKD1_k127_107095_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 503.0
HKD1_k127_107095_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 450.0
HKD1_k127_107095_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 417.0
HKD1_k127_107095_6 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 405.0
HKD1_k127_107095_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 316.0
HKD1_k127_107095_8 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 298.0
HKD1_k127_107095_9 PFAM Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 289.0
HKD1_k127_1094741_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 577.0
HKD1_k127_1094741_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 568.0
HKD1_k127_1094741_10 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000002578 141.0
HKD1_k127_1094741_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000000000000000000001875 158.0
HKD1_k127_1094741_12 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000008518 132.0
HKD1_k127_1094741_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000002924 81.0
HKD1_k127_1094741_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 421.0
HKD1_k127_1094741_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 396.0
HKD1_k127_1094741_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 407.0
HKD1_k127_1094741_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 397.0
HKD1_k127_1094741_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 375.0
HKD1_k127_1094741_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 348.0
HKD1_k127_1094741_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 319.0
HKD1_k127_1094741_9 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 316.0
HKD1_k127_1095306_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.824e-213 694.0
HKD1_k127_1095306_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 6.722e-196 634.0
HKD1_k127_1095306_10 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002223 293.0
HKD1_k127_1095306_11 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 280.0
HKD1_k127_1095306_12 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000004988 265.0
HKD1_k127_1095306_13 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000001906 242.0
HKD1_k127_1095306_14 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000001628 236.0
HKD1_k127_1095306_15 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000002969 198.0
HKD1_k127_1095306_16 low molecular weight K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000002443 190.0
HKD1_k127_1095306_17 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.000000000000000000000000000000000000000000000146 177.0
HKD1_k127_1095306_18 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000501 127.0
HKD1_k127_1095306_19 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000001334 100.0
HKD1_k127_1095306_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 516.0
HKD1_k127_1095306_20 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000001892 93.0
HKD1_k127_1095306_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 433.0
HKD1_k127_1095306_4 Competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 451.0
HKD1_k127_1095306_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 379.0
HKD1_k127_1095306_6 ErfK YbiS YcfS YnhG family protein K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 323.0
HKD1_k127_1095306_7 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 319.0
HKD1_k127_1095306_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 311.0
HKD1_k127_1095306_9 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 301.0
HKD1_k127_1149884_0 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 492.0
HKD1_k127_1149884_1 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 468.0
HKD1_k127_1149884_2 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 441.0
HKD1_k127_1149884_3 PrpF protein K16514 - 5.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 325.0
HKD1_k127_1149884_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005564 269.0
HKD1_k127_1149884_5 Amidohydrolase K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000000000000000003364 220.0
HKD1_k127_1201856_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 480.0
HKD1_k127_1201856_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 443.0
HKD1_k127_1201856_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 368.0
HKD1_k127_1201856_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 330.0
HKD1_k127_1201856_4 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 331.0
HKD1_k127_1201856_5 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002439 255.0
HKD1_k127_1201856_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000001043 194.0
HKD1_k127_1201856_7 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000000000000008012 145.0
HKD1_k127_122749_0 PhoQ Sensor K12257 - - 0.0 1692.0
HKD1_k127_122749_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1183.0
HKD1_k127_122749_10 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 347.0
HKD1_k127_122749_11 Tetratricopeptide repeats K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 350.0
HKD1_k127_122749_12 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 310.0
HKD1_k127_122749_13 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 312.0
HKD1_k127_122749_14 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000973 275.0
HKD1_k127_122749_15 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003481 259.0
HKD1_k127_122749_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006411 255.0
HKD1_k127_122749_17 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004017 253.0
HKD1_k127_122749_18 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000008064 214.0
HKD1_k127_122749_19 MucB/RseB C-terminal domain K03598 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - 0.0000000000000000000000000000000000000000000000000000001793 207.0
HKD1_k127_122749_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.045e-302 942.0
HKD1_k127_122749_20 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000005683 213.0
HKD1_k127_122749_21 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000004231 198.0
HKD1_k127_122749_22 CYTH K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000008089 191.0
HKD1_k127_122749_23 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000659 191.0
HKD1_k127_122749_24 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000005972 182.0
HKD1_k127_122749_25 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000002689 192.0
HKD1_k127_122749_26 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000002873 173.0
HKD1_k127_122749_27 phosphoribosyltransferase K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000005835 164.0
HKD1_k127_122749_28 cellulase activity - - - 0.000000000000000000000000000000000000001398 165.0
HKD1_k127_122749_29 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000002259 155.0
HKD1_k127_122749_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.02e-281 875.0
HKD1_k127_122749_30 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000004921 136.0
HKD1_k127_122749_31 succinate dehydrogenase K00241 - - 0.0000000000000000000000000004787 118.0
HKD1_k127_122749_32 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0016740,GO:0016772,GO:0016780,GO:0044238,GO:0071704,GO:1901576 2.7.8.7 0.0000000000000000000000003984 115.0
HKD1_k127_122749_33 succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.00000000000000000000003184 104.0
HKD1_k127_122749_34 cell redox homeostasis K00384 - 1.8.1.9 0.0000000000005601 75.0
HKD1_k127_122749_35 Flavinator of succinate dehydrogenase K09159 - - 0.000000000002002 70.0
HKD1_k127_122749_36 Peptidoglycan-binding protein, CsiV - - - 0.000000000119 72.0
HKD1_k127_122749_37 Protein of unknown function (DUF1674) - - - 0.00000002354 62.0
HKD1_k127_122749_38 Transposase - - - 0.0000002889 53.0
HKD1_k127_122749_39 Domain of unknown function (DUF4845) - - - 0.0000004409 57.0
HKD1_k127_122749_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 503.0
HKD1_k127_122749_40 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E K03597 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000001376 57.0
HKD1_k127_122749_41 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0002263 49.0
HKD1_k127_122749_5 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 509.0
HKD1_k127_122749_6 two-component system sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 467.0
HKD1_k127_122749_7 COG4257 Streptogramin lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 442.0
HKD1_k127_122749_8 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 423.0
HKD1_k127_122749_9 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 426.0
HKD1_k127_1228527_0 acetolactate synthase K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 2.839e-285 889.0
HKD1_k127_1228527_1 receptor - - - 1.809e-231 743.0
HKD1_k127_1228527_10 acetolactate synthase, small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000005135 171.0
HKD1_k127_1228527_11 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000002681 166.0
HKD1_k127_1228527_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.000000000003149 67.0
HKD1_k127_1228527_13 - - - - 0.0000000000252 67.0
HKD1_k127_1228527_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 540.0
HKD1_k127_1228527_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 467.0
HKD1_k127_1228527_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 447.0
HKD1_k127_1228527_5 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 425.0
HKD1_k127_1228527_6 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 383.0
HKD1_k127_1228527_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 314.0
HKD1_k127_1228527_8 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 262.0
HKD1_k127_1228527_9 AAA-like domain - - - 0.00000000000000000000000000000000000000000000000000000004134 226.0
HKD1_k127_1265952_0 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 435.0
HKD1_k127_1265952_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 428.0
HKD1_k127_1265952_2 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 376.0
HKD1_k127_1265952_3 sulfate ABC transporter, inner membrane subunit CysT K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 339.0
HKD1_k127_1265952_4 Glutathione-dependent formaldehyde-activating enzyme K03396 - 4.4.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
HKD1_k127_1265952_5 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000538 242.0
HKD1_k127_1265952_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000008185 71.0
HKD1_k127_1265952_7 - - - - 0.000009184 55.0
HKD1_k127_1265952_8 ATPase activity K02045 - 3.6.3.25 0.000009277 57.0
HKD1_k127_127923_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.69e-268 837.0
HKD1_k127_127923_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.124e-231 723.0
HKD1_k127_127923_10 zinc-ribbon domain - - - 0.0000000003214 61.0
HKD1_k127_127923_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 623.0
HKD1_k127_127923_3 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000285 251.0
HKD1_k127_127923_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000003038 236.0
HKD1_k127_127923_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000003518 188.0
HKD1_k127_127923_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000003405 168.0
HKD1_k127_127923_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000009258 165.0
HKD1_k127_127923_8 Thioredoxin-like - - - 0.00000000000000000000000001042 119.0
HKD1_k127_127923_9 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000003289 106.0
HKD1_k127_12930_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1234.0
HKD1_k127_12930_1 Belongs to the ABC transporter superfamily K02031,K02032 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 8.549e-306 951.0
HKD1_k127_12930_10 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 476.0
HKD1_k127_12930_11 N-terminal TM domain of oligopeptide transport permease C K02034 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 396.0
HKD1_k127_12930_12 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 389.0
HKD1_k127_12930_13 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 384.0
HKD1_k127_12930_14 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 364.0
HKD1_k127_12930_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 302.0
HKD1_k127_12930_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 289.0
HKD1_k127_12930_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001863 275.0
HKD1_k127_12930_18 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009498 270.0
HKD1_k127_12930_19 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002713 289.0
HKD1_k127_12930_2 - - - - 9.512e-298 930.0
HKD1_k127_12930_20 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008424 259.0
HKD1_k127_12930_21 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000005162 223.0
HKD1_k127_12930_22 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000006841 195.0
HKD1_k127_12930_23 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000001197 192.0
HKD1_k127_12930_24 Prolyl 4-hydroxylase alpha subunit homologues. K07336 - - 0.00000000000000000000000000000000000000000000000002615 188.0
HKD1_k127_12930_25 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000001979 192.0
HKD1_k127_12930_26 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000001144 196.0
HKD1_k127_12930_27 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000006563 182.0
HKD1_k127_12930_28 - - - - 0.000000000000000000000000000000000000000000003832 180.0
HKD1_k127_12930_29 cellulase activity - - - 0.00000000000000000000000000000000000000001048 169.0
HKD1_k127_12930_3 Peptidase family M49 K01277 - 3.4.14.4 9.253e-253 797.0
HKD1_k127_12930_30 DNA-templated transcription, initiation K03088,K03091 - - 0.00000000000000000000000000000000000000002743 160.0
HKD1_k127_12930_31 MarC family integral membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000008009 166.0
HKD1_k127_12930_32 Exopolysaccharide synthesis, ExoD - - - 0.000000000000000000000000000000000000003066 162.0
HKD1_k127_12930_33 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000001765 155.0
HKD1_k127_12930_34 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000005616 140.0
HKD1_k127_12930_35 - - - - 0.0000000000000000000000000001199 131.0
HKD1_k127_12930_36 phosphoenolpyruvate carboxylase activity K01595 - 4.1.1.31 0.0000000000000000000000000001438 118.0
HKD1_k127_12930_37 - - - - 0.0000000000000000000000000004673 124.0
HKD1_k127_12930_38 - - - - 0.00000000000000000000000001744 115.0
HKD1_k127_12930_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043295,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072341,GO:1900750,GO:1901681,GO:1904680 - 3.729e-208 661.0
HKD1_k127_12930_40 - - - - 0.000000000000000007696 100.0
HKD1_k127_12930_41 transport system, permease component K01992 - - 0.0000000000000003375 93.0
HKD1_k127_12930_44 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000207 68.0
HKD1_k127_12930_45 Protein of unknown function (DUF2845) - - - 0.0000001259 62.0
HKD1_k127_12930_5 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 578.0
HKD1_k127_12930_6 Glycosyl transferase family group 2 K03669 GO:0005575,GO:0016020 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 609.0
HKD1_k127_12930_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 524.0
HKD1_k127_12930_8 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 515.0
HKD1_k127_12930_9 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 473.0
HKD1_k127_1293042_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1505.0
HKD1_k127_1293042_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1285.0
HKD1_k127_1293042_10 Dehydrogenase K00117 - 1.1.5.2 1.128e-209 676.0
HKD1_k127_1293042_100 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0002575 49.0
HKD1_k127_1293042_101 - - - - 0.0002654 48.0
HKD1_k127_1293042_102 Metallo-beta-lactamase superfamily - - - 0.0004289 53.0
HKD1_k127_1293042_11 Sugar phosphate isomerases epimerases - - - 8.128e-204 637.0
HKD1_k127_1293042_12 Belongs to the peptidase S1B family - - - 6.345e-196 632.0
HKD1_k127_1293042_13 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 615.0
HKD1_k127_1293042_14 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 628.0
HKD1_k127_1293042_15 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 601.0
HKD1_k127_1293042_16 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 578.0
HKD1_k127_1293042_17 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 570.0
HKD1_k127_1293042_18 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 550.0
HKD1_k127_1293042_19 Short chain fatty acid transporter K02106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 519.0
HKD1_k127_1293042_2 Dehydrogenase E1 component K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.0 1097.0
HKD1_k127_1293042_20 Belongs to the citrate synthase family K01659 GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 511.0
HKD1_k127_1293042_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 505.0
HKD1_k127_1293042_22 Carbohydrate-selective porin, OprB family K16079,K16080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 511.0
HKD1_k127_1293042_23 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 482.0
HKD1_k127_1293042_24 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 432.0
HKD1_k127_1293042_25 FAD binding domain K00480 - 1.14.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 418.0
HKD1_k127_1293042_26 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 399.0
HKD1_k127_1293042_27 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 411.0
HKD1_k127_1293042_28 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 411.0
HKD1_k127_1293042_29 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 386.0
HKD1_k127_1293042_3 synthetase K01908 - 6.2.1.17 3.865e-275 859.0
HKD1_k127_1293042_30 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 362.0
HKD1_k127_1293042_31 cytochrome K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
HKD1_k127_1293042_32 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 318.0
HKD1_k127_1293042_33 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 316.0
HKD1_k127_1293042_34 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 333.0
HKD1_k127_1293042_35 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 334.0
HKD1_k127_1293042_36 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 309.0
HKD1_k127_1293042_37 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 307.0
HKD1_k127_1293042_38 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 292.0
HKD1_k127_1293042_39 outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 295.0
HKD1_k127_1293042_4 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 3.128e-268 847.0
HKD1_k127_1293042_40 PFAM NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 262.0
HKD1_k127_1293042_41 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
HKD1_k127_1293042_42 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003438 268.0
HKD1_k127_1293042_43 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000002164 250.0
HKD1_k127_1293042_44 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002064 251.0
HKD1_k127_1293042_45 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002345 246.0
HKD1_k127_1293042_46 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004218 254.0
HKD1_k127_1293042_47 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000003494 243.0
HKD1_k127_1293042_48 aldo-keto reductase (NADP) activity K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000001276 248.0
HKD1_k127_1293042_49 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001869 241.0
HKD1_k127_1293042_5 DNA helicase K03654 - 3.6.4.12 3.165e-248 782.0
HKD1_k127_1293042_50 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000002192 233.0
HKD1_k127_1293042_51 protein conserved in bacteria K09966 - - 0.0000000000000000000000000000000000000000000000000000000001152 206.0
HKD1_k127_1293042_52 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000009216 207.0
HKD1_k127_1293042_53 - - - - 0.000000000000000000000000000000000000000000000000000000002238 210.0
HKD1_k127_1293042_54 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000003494 210.0
HKD1_k127_1293042_55 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.00000000000000000000000000000000000000000000000000000008726 204.0
HKD1_k127_1293042_56 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000007271 198.0
HKD1_k127_1293042_57 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000003539 190.0
HKD1_k127_1293042_58 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000000000000000000000000005744 185.0
HKD1_k127_1293042_59 ABC transporter substrate-binding protein - - - 0.000000000000000000000000000000000000000000000009698 175.0
HKD1_k127_1293042_6 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 3.472e-244 780.0
HKD1_k127_1293042_60 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000001638 179.0
HKD1_k127_1293042_61 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000002494 172.0
HKD1_k127_1293042_62 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000002358 164.0
HKD1_k127_1293042_63 Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000000001601 158.0
HKD1_k127_1293042_64 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000003205 155.0
HKD1_k127_1293042_65 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000001038 167.0
HKD1_k127_1293042_66 - - - - 0.000000000000000000000000000000000000001093 161.0
HKD1_k127_1293042_67 transcriptional regulator - - - 0.00000000000000000000000000000000000006379 151.0
HKD1_k127_1293042_68 - - - - 0.00000000000000000000000000000000000032 155.0
HKD1_k127_1293042_69 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000004173 132.0
HKD1_k127_1293042_7 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 8.271e-225 700.0
HKD1_k127_1293042_70 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000001162 141.0
HKD1_k127_1293042_71 - - - - 0.0000000000000000000000000000001962 139.0
HKD1_k127_1293042_72 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000004173 135.0
HKD1_k127_1293042_73 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000005865 125.0
HKD1_k127_1293042_74 MAPEG family - - - 0.0000000000000000000000000001111 123.0
HKD1_k127_1293042_75 - - - - 0.0000000000000000000000000005485 119.0
HKD1_k127_1293042_77 - - - - 0.000000000000000000000000001283 121.0
HKD1_k127_1293042_78 phospholipase Carboxylesterase - - - 0.00000000000000000000000001042 121.0
HKD1_k127_1293042_79 Ankyrin repeat and kinase domain containing 1 K16289 - 2.7.11.1 0.00000000000000000000000004144 124.0
HKD1_k127_1293042_8 2-methylcitrate dehydratase K01720 - 4.2.1.79 5.84e-223 706.0
HKD1_k127_1293042_80 acetyltransferase - - - 0.0000000000000000000000002851 114.0
HKD1_k127_1293042_81 COG3474 Cytochrome c2 K08738 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - 0.00000000000000000000002209 115.0
HKD1_k127_1293042_82 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000007766 107.0
HKD1_k127_1293042_84 - - - - 0.00000000000000000002632 98.0
HKD1_k127_1293042_85 general secretion pathway protein K02450 - - 0.00000000000000000142 101.0
HKD1_k127_1293042_86 - - - - 0.0000000000000004994 89.0
HKD1_k127_1293042_87 - - - - 0.000000000000001174 88.0
HKD1_k127_1293042_88 - - - - 0.000000000000002549 90.0
HKD1_k127_1293042_89 transposition K07483,K07497 - - 0.000000000000002961 77.0
HKD1_k127_1293042_9 DNA topological change K03168 - 5.99.1.2 4.995e-213 689.0
HKD1_k127_1293042_90 - - - - 0.000000000001245 73.0
HKD1_k127_1293042_91 TonB C terminal K03646 - - 0.00000000003165 74.0
HKD1_k127_1293042_92 - - - - 0.00000000003239 74.0
HKD1_k127_1293042_93 - - - - 0.00000000007052 70.0
HKD1_k127_1293042_95 - - - - 0.0000000009617 66.0
HKD1_k127_1293042_96 - - - - 0.000000009597 63.0
HKD1_k127_1293042_97 SnoaL-like domain - - - 0.0000001177 61.0
HKD1_k127_1293042_98 - - - - 0.00004721 48.0
HKD1_k127_1413487_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1056.0
HKD1_k127_1413487_1 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 1.005e-244 784.0
HKD1_k127_1413487_10 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 346.0
HKD1_k127_1413487_11 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 331.0
HKD1_k127_1413487_12 ABC-type molybdate transport system, permease component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 302.0
HKD1_k127_1413487_13 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 302.0
HKD1_k127_1413487_14 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001065 267.0
HKD1_k127_1413487_15 COG3103 SH3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001177 246.0
HKD1_k127_1413487_16 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000001608 229.0
HKD1_k127_1413487_17 XdhC and CoxI family - - - 0.000000000000000000000000000000000000000000000000000000000000002487 234.0
HKD1_k127_1413487_18 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000002338 192.0
HKD1_k127_1413487_19 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.000000000000000000000000000000000003912 145.0
HKD1_k127_1413487_2 Concanavalin A-like lectin/glucanases superfamily - - - 4.882e-244 781.0
HKD1_k127_1413487_20 Pilin (bacterial filament) K02650,K02655 - - 0.00000000000000000000000000000000001105 147.0
HKD1_k127_1413487_22 Domain of unknown function (DUF4266) - - - 0.000000000000000000000009952 102.0
HKD1_k127_1413487_23 ABC transporter K02003 - - 0.0000000000000000000006752 95.0
HKD1_k127_1413487_24 SOCS_box - - - 0.00000004412 62.0
HKD1_k127_1413487_25 Tetratricopeptide repeat - - - 0.000006179 55.0
HKD1_k127_1413487_26 Biopolymer transporter TonB K03832 - - 0.0006241 51.0
HKD1_k127_1413487_3 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.241e-237 747.0
HKD1_k127_1413487_4 - - - - 1.06e-199 636.0
HKD1_k127_1413487_5 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 431.0
HKD1_k127_1413487_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 424.0
HKD1_k127_1413487_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 406.0
HKD1_k127_1413487_8 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 405.0
HKD1_k127_1413487_9 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 352.0
HKD1_k127_1472316_0 Dehydrogenase E1 component K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.0 1108.0
HKD1_k127_1472316_1 Aminotransferase class-III K00823 - 2.6.1.19 5.737e-233 728.0
HKD1_k127_1472316_10 MltA-interacting protein MipA K07274 - - 0.0000000000000000000000000000000000008169 150.0
HKD1_k127_1472316_11 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000003538 154.0
HKD1_k127_1472316_12 COG3474 Cytochrome c2 K08738 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000001392 123.0
HKD1_k127_1472316_13 Multidrug Resistance protein K03297 - - 0.00000000000000000007599 94.0
HKD1_k127_1472316_14 Multidrug Resistance protein K12962 - - 0.0000000000000006815 87.0
HKD1_k127_1472316_15 Phosphopantetheine attachment site K02078 - - 0.000000000001633 70.0
HKD1_k127_1472316_16 - - - - 0.00000000003239 74.0
HKD1_k127_1472316_17 - - - - 0.0000000397 63.0
HKD1_k127_1472316_18 O-methyltransferase - - - 0.0006341 44.0
HKD1_k127_1472316_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 556.0
HKD1_k127_1472316_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 482.0
HKD1_k127_1472316_4 Peptidogalycan biosysnthesis/recognition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 416.0
HKD1_k127_1472316_5 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 413.0
HKD1_k127_1472316_6 Belongs to the arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 349.0
HKD1_k127_1472316_7 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 317.0
HKD1_k127_1472316_8 Putative Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000003359 211.0
HKD1_k127_1472316_9 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000000000000000000000000007826 185.0
HKD1_k127_157068_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18299 - - 0.0 1428.0
HKD1_k127_157068_1 M13 family peptidase K01415,K07386 - 3.4.24.71 7.043e-213 684.0
HKD1_k127_157068_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001436 278.0
HKD1_k127_157068_11 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001303 280.0
HKD1_k127_157068_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001441 256.0
HKD1_k127_157068_13 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000000000000000000000000000001202 223.0
HKD1_k127_157068_14 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000006413 220.0
HKD1_k127_157068_15 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000001283 205.0
HKD1_k127_157068_16 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000006087 192.0
HKD1_k127_157068_17 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000005912 185.0
HKD1_k127_157068_18 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000001334 177.0
HKD1_k127_157068_19 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000007747 160.0
HKD1_k127_157068_2 PQQ enzyme repeat K00117 - 1.1.5.2 5.618e-204 656.0
HKD1_k127_157068_20 SnoaL-like domain - - - 0.00000000000000000000000000000000000003575 151.0
HKD1_k127_157068_21 Flavodoxin-like fold - - - 0.00000000000000000000000000000000002346 141.0
HKD1_k127_157068_22 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000003513 138.0
HKD1_k127_157068_23 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000453 147.0
HKD1_k127_157068_24 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000005088 134.0
HKD1_k127_157068_25 YCII-related domain - - - 0.000000000000000000000000000000001306 146.0
HKD1_k127_157068_26 amine dehydrogenase activity K12287 - - 0.00000000000003636 85.0
HKD1_k127_157068_27 thiolester hydrolase activity K06889 - - 0.000000000008187 78.0
HKD1_k127_157068_28 - - - - 0.000000000009779 76.0
HKD1_k127_157068_29 decarboxylase K01607 - 4.1.1.44 0.00000000003599 74.0
HKD1_k127_157068_3 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 392.0
HKD1_k127_157068_30 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000437 71.0
HKD1_k127_157068_32 - K01992 - - 0.00000007101 63.0
HKD1_k127_157068_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 398.0
HKD1_k127_157068_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 381.0
HKD1_k127_157068_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 378.0
HKD1_k127_157068_7 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 358.0
HKD1_k127_157068_8 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 295.0
HKD1_k127_157068_9 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 284.0
HKD1_k127_1637503_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000185 289.0
HKD1_k127_1717669_0 Nitric oxide reductase large subunit K04561 - 1.7.2.5 0.0 1172.0
HKD1_k127_1717669_1 TonB dependent receptor K02014 - - 1.353e-280 888.0
HKD1_k127_1717669_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004379 227.0
HKD1_k127_1717669_11 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000003088 216.0
HKD1_k127_1717669_12 deacetylase K06986 - - 0.00000000000000000000000000000000000000000000000000000006322 209.0
HKD1_k127_1717669_13 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000000000144 198.0
HKD1_k127_1717669_14 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000000004695 200.0
HKD1_k127_1717669_15 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000005672 142.0
HKD1_k127_1717669_16 RNA recognition motif - - - 0.00000000000000000000000000000004313 126.0
HKD1_k127_1717669_17 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000006275 128.0
HKD1_k127_1717669_19 - - - - 0.0000000000000000000000002285 119.0
HKD1_k127_1717669_2 ABC transporter transmembrane region K06147,K11085 - - 5.62e-204 651.0
HKD1_k127_1717669_20 - - - - 0.0000000000000000000000007519 117.0
HKD1_k127_1717669_21 YCII-related domain - - - 0.000000000000000000000002399 106.0
HKD1_k127_1717669_22 - - - - 0.000000000000000000000002665 117.0
HKD1_k127_1717669_23 - - - - 0.0000000000000000000000587 108.0
HKD1_k127_1717669_25 - - - - 0.0000000419 63.0
HKD1_k127_1717669_26 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0004353 44.0
HKD1_k127_1717669_3 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 501.0
HKD1_k127_1717669_4 metallo-beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 418.0
HKD1_k127_1717669_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 339.0
HKD1_k127_1717669_6 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 327.0
HKD1_k127_1717669_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 327.0
HKD1_k127_1717669_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005869 255.0
HKD1_k127_1717669_9 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004335 241.0
HKD1_k127_1719437_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 587.0
HKD1_k127_1719437_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 308.0
HKD1_k127_1719437_2 - - - - 0.00000000000000000000000000000000001689 145.0
HKD1_k127_1719437_3 - - - - 0.0000000000000000002376 102.0
HKD1_k127_1719437_4 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000007926 82.0
HKD1_k127_1719437_5 SCP-2 sterol transfer family - - - 0.00000000000001326 83.0
HKD1_k127_1719437_6 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000001588 81.0
HKD1_k127_1719437_8 Haloacid dehalogenase-like hydrolase - - - 0.00000007026 65.0
HKD1_k127_173962_0 ABC transporter K06147,K18893 - - 2.954e-242 766.0
HKD1_k127_173962_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 424.0
HKD1_k127_173962_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 389.0
HKD1_k127_173962_3 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 323.0
HKD1_k127_173962_4 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 312.0
HKD1_k127_173962_5 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001059 258.0
HKD1_k127_173962_7 Phosphopantetheine attachment site - - - 0.00000000004746 66.0
HKD1_k127_177504_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1452.0
HKD1_k127_177504_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 1.541e-221 696.0
HKD1_k127_177504_10 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
HKD1_k127_177504_11 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000006848 244.0
HKD1_k127_177504_12 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000003152 238.0
HKD1_k127_177504_13 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000297 193.0
HKD1_k127_177504_14 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000007408 168.0
HKD1_k127_177504_15 Membrane - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000009803 109.0
HKD1_k127_177504_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 617.0
HKD1_k127_177504_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 437.0
HKD1_k127_177504_4 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 430.0
HKD1_k127_177504_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 407.0
HKD1_k127_177504_6 Major facilitator K05819,K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 401.0
HKD1_k127_177504_7 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 338.0
HKD1_k127_177504_8 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 340.0
HKD1_k127_177504_9 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 326.0
HKD1_k127_1937596_0 - - - - 1.152e-230 737.0
HKD1_k127_1937596_1 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 512.0
HKD1_k127_1937596_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000007603 172.0
HKD1_k127_1937596_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000848 170.0
HKD1_k127_1937596_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001607 158.0
HKD1_k127_1937596_13 Thioredoxin-like - - - 0.0000000000000000000000000000006303 128.0
HKD1_k127_1937596_14 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000002708 104.0
HKD1_k127_1937596_15 - - - - 0.000000000000001848 88.0
HKD1_k127_1937596_16 - - - - 0.0000000003858 73.0
HKD1_k127_1937596_17 - - - - 0.000003744 58.0
HKD1_k127_1937596_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 316.0
HKD1_k127_1937596_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007171 283.0
HKD1_k127_1937596_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000006665 248.0
HKD1_k127_1937596_6 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000003432 243.0
HKD1_k127_1937596_7 peptidase - - - 0.000000000000000000000000000000000000000000000000000000006556 220.0
HKD1_k127_1937596_8 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000002737 199.0
HKD1_k127_1961754_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 574.0
HKD1_k127_1961754_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 402.0
HKD1_k127_1961754_2 heptosyltransferase II K02843 - - 0.000000000000000000000000001587 117.0
HKD1_k127_1961754_3 protein conserved in bacteria - - - 0.00000000000000000006695 91.0
HKD1_k127_201334_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1292.0
HKD1_k127_201334_1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K20940 - 1.14.13.218 1.448e-221 695.0
HKD1_k127_201334_10 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 522.0
HKD1_k127_201334_11 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
HKD1_k127_201334_12 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 451.0
HKD1_k127_201334_13 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 435.0
HKD1_k127_201334_14 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 407.0
HKD1_k127_201334_15 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 416.0
HKD1_k127_201334_16 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 355.0
HKD1_k127_201334_17 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 359.0
HKD1_k127_201334_18 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
HKD1_k127_201334_19 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 329.0
HKD1_k127_201334_2 SbmA/BacA-like family - - - 4.218e-220 700.0
HKD1_k127_201334_20 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 281.0
HKD1_k127_201334_21 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000011 271.0
HKD1_k127_201334_22 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000002981 258.0
HKD1_k127_201334_23 KDPG and KHG aldolase K01631 - 4.1.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000005762 258.0
HKD1_k127_201334_24 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000003829 243.0
HKD1_k127_201334_25 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000006894 229.0
HKD1_k127_201334_26 - - - - 0.000000000000000000000000000000000000000000000000002081 203.0
HKD1_k127_201334_27 Phosphatidylethanolamine-binding protein - - - 0.0000000000000000000000000000000000000000001959 166.0
HKD1_k127_201334_28 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000138 171.0
HKD1_k127_201334_29 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000001506 164.0
HKD1_k127_201334_3 SbmA/BacA-like family - - - 2.716e-216 689.0
HKD1_k127_201334_30 - - - - 0.000000000000000000000000000000000008094 149.0
HKD1_k127_201334_31 - - - - 0.0000000000000000000000000000003163 137.0
HKD1_k127_201334_33 - - - - 0.000000000000000000000000002846 117.0
HKD1_k127_201334_34 - - - - 0.00000000000000002249 88.0
HKD1_k127_201334_35 intracellular protease amidase K05520 - 3.5.1.124 0.0000000000009754 74.0
HKD1_k127_201334_4 Putative glucoamylase - - - 1.678e-210 665.0
HKD1_k127_201334_5 Protein of unknown function (DUF1587) - - - 6.133e-194 631.0
HKD1_k127_201334_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 623.0
HKD1_k127_201334_7 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 525.0
HKD1_k127_201334_8 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 512.0
HKD1_k127_201334_9 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 529.0
HKD1_k127_2029444_1 Cytochrome C biogenesis protein transmembrane region - - - 3.798e-244 775.0
HKD1_k127_2029444_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 295.0
HKD1_k127_2029444_11 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001311 285.0
HKD1_k127_2029444_12 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006838 278.0
HKD1_k127_2029444_13 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002863 274.0
HKD1_k127_2029444_14 regulation of cobalamin metabolic process K11390 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008169 259.0
HKD1_k127_2029444_15 IclR helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002598 248.0
HKD1_k127_2029444_16 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 244.0
HKD1_k127_2029444_17 hopanoid biosynthesis associated protein HpnK K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000005595 262.0
HKD1_k127_2029444_18 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001152 235.0
HKD1_k127_2029444_19 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000003566 227.0
HKD1_k127_2029444_2 belongs to the aldehyde dehydrogenase family K00146 - 1.2.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 574.0
HKD1_k127_2029444_20 COG2015, Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000001925 241.0
HKD1_k127_2029444_21 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000000008484 222.0
HKD1_k127_2029444_22 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000000000000000000000000000000000000001412 208.0
HKD1_k127_2029444_23 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000002998 177.0
HKD1_k127_2029444_24 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000002667 157.0
HKD1_k127_2029444_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000003614 166.0
HKD1_k127_2029444_26 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000009036 143.0
HKD1_k127_2029444_27 Methyltransferase domain - - - 0.00000000000000000000000000002121 130.0
HKD1_k127_2029444_28 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000001047 121.0
HKD1_k127_2029444_29 - - - - 0.0000000000000000000000001765 109.0
HKD1_k127_2029444_3 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 465.0
HKD1_k127_2029444_30 Domain of unknown function (DUF4136) - - - 0.00000000002526 72.0
HKD1_k127_2029444_31 Predicted membrane protein (DUF2231) - - - 0.0000000004127 70.0
HKD1_k127_2029444_32 PFAM GtrA-like protein - - - 0.00000001135 62.0
HKD1_k127_2029444_33 Polysaccharide biosynthesis protein - - - 0.0005371 52.0
HKD1_k127_2029444_4 SMP-30/Gluconolaconase/LRE-like region K01053,K13735 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 437.0
HKD1_k127_2029444_5 Aspartate tyrosine aromatic aminotransferase K00813,K00832 - 2.6.1.1,2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 438.0
HKD1_k127_2029444_6 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 403.0
HKD1_k127_2029444_7 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 374.0
HKD1_k127_2029444_8 NADPH:quinone reductase activity K00344 GO:0000166,GO:0003674,GO:0003824,GO:0003960,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0010941,GO:0016491,GO:0016651,GO:0016655,GO:0019362,GO:0019637,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0042981,GO:0043067,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0048038,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0051186,GO:0055086,GO:0055114,GO:0065007,GO:0070402,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 370.0
HKD1_k127_2029444_9 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 319.0
HKD1_k127_2033188_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1108.0
HKD1_k127_2033188_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.293e-249 784.0
HKD1_k127_2033188_10 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 313.0
HKD1_k127_2033188_11 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 297.0
HKD1_k127_2033188_12 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006939 278.0
HKD1_k127_2033188_13 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004998 263.0
HKD1_k127_2033188_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000007312 201.0
HKD1_k127_2033188_17 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.00000000000000000000000000000000000000000000003427 172.0
HKD1_k127_2033188_19 Cytochrome c - - - 0.00000000000000000000000000003122 123.0
HKD1_k127_2033188_2 L-lactate permease K03303 - - 4.681e-195 622.0
HKD1_k127_2033188_20 Universal stress protein K14055 GO:0000302,GO:0001539,GO:0006928,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0033554,GO:0034599,GO:0034614,GO:0034644,GO:0035690,GO:0040011,GO:0042221,GO:0042493,GO:0042542,GO:0042710,GO:0044010,GO:0044764,GO:0046677,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071478,GO:0071482,GO:0071973,GO:0097237,GO:0097588,GO:0104004,GO:1901700,GO:1901701 - 0.000000000000000000000000001176 125.0
HKD1_k127_2033188_21 Universal stress protein K14055 GO:0000302,GO:0001539,GO:0006928,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0033554,GO:0034599,GO:0034614,GO:0034644,GO:0035690,GO:0040011,GO:0042221,GO:0042493,GO:0042542,GO:0042710,GO:0044010,GO:0044764,GO:0046677,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071478,GO:0071482,GO:0071973,GO:0097237,GO:0097588,GO:0104004,GO:1901700,GO:1901701 - 0.000000000000000000000002803 115.0
HKD1_k127_2033188_22 MerR HTH family regulatory protein K18997 - - 0.0000000000000000001303 92.0
HKD1_k127_2033188_23 - - - - 0.00000000003912 70.0
HKD1_k127_2033188_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000002308 58.0
HKD1_k127_2033188_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 526.0
HKD1_k127_2033188_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 491.0
HKD1_k127_2033188_5 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 487.0
HKD1_k127_2033188_6 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 464.0
HKD1_k127_2033188_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 441.0
HKD1_k127_2033188_8 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 346.0
HKD1_k127_2033188_9 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 343.0
HKD1_k127_2041577_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.125e-223 703.0
HKD1_k127_2041577_1 PQQ enzyme repeat K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 621.0
HKD1_k127_2041577_10 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005827 271.0
HKD1_k127_2041577_11 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.000000000000000000000000000000000000000000000000000000000000001557 233.0
HKD1_k127_2041577_12 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000008233 228.0
HKD1_k127_2041577_13 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000007917 174.0
HKD1_k127_2041577_14 - - - - 0.00000000000000000000000000000000000001838 160.0
HKD1_k127_2041577_15 - - - - 0.00000000000000000000000000000000000006699 156.0
HKD1_k127_2041577_16 FMN-binding domain protein - - - 0.0000000000000000000000000000000000004972 151.0
HKD1_k127_2041577_17 - - - - 0.0000000000000000000000000000000000013 142.0
HKD1_k127_2041577_18 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000001529 138.0
HKD1_k127_2041577_19 ApbE family - - - 0.0000000000000000000000000000164 128.0
HKD1_k127_2041577_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 630.0
HKD1_k127_2041577_20 (twin-arginine translocation) pathway signal - - - 0.00000000000000000001831 98.0
HKD1_k127_2041577_21 - - - - 0.00000008229 64.0
HKD1_k127_2041577_3 PQQ-like domain K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 593.0
HKD1_k127_2041577_4 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 530.0
HKD1_k127_2041577_5 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 389.0
HKD1_k127_2041577_6 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 367.0
HKD1_k127_2041577_7 Dihydroxyacetone kinase K00863 - 2.7.1.28,2.7.1.29,4.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 351.0
HKD1_k127_2041577_8 FAD linked K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001164 281.0
HKD1_k127_2041577_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001339 271.0
HKD1_k127_2047896_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 2.432e-251 803.0
HKD1_k127_2047896_1 FtsX-like permease family K02004 - - 6.044e-195 640.0
HKD1_k127_2047896_10 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 416.0
HKD1_k127_2047896_11 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 405.0
HKD1_k127_2047896_12 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 392.0
HKD1_k127_2047896_13 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 394.0
HKD1_k127_2047896_14 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 388.0
HKD1_k127_2047896_15 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 344.0
HKD1_k127_2047896_16 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 351.0
HKD1_k127_2047896_17 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 309.0
HKD1_k127_2047896_18 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 309.0
HKD1_k127_2047896_19 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005041 243.0
HKD1_k127_2047896_2 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 611.0
HKD1_k127_2047896_20 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000001307 203.0
HKD1_k127_2047896_21 TonB-dependent receptor, beta-barrel - - - 0.0000000000000000000000000000000000000000000001943 183.0
HKD1_k127_2047896_22 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000002978 179.0
HKD1_k127_2047896_23 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000003019 163.0
HKD1_k127_2047896_24 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000005552 158.0
HKD1_k127_2047896_25 - - - - 0.00000000000000002351 96.0
HKD1_k127_2047896_26 Transcriptional regulator K18301 - - 0.0000000000002302 79.0
HKD1_k127_2047896_27 - - - - 0.000000000001497 75.0
HKD1_k127_2047896_28 - - - - 0.00000007173 63.0
HKD1_k127_2047896_29 peptidyl-tyrosine sulfation - - - 0.0001025 53.0
HKD1_k127_2047896_3 Protein involved in UDP-N-acetylmuramate dehydrogenase activity and amino sugar metabolic process K05797 - 1.17.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 599.0
HKD1_k127_2047896_30 Bacterial regulatory proteins, tetR family - - - 0.0001409 52.0
HKD1_k127_2047896_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 595.0
HKD1_k127_2047896_5 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 521.0
HKD1_k127_2047896_6 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 501.0
HKD1_k127_2047896_7 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 430.0
HKD1_k127_2047896_8 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 412.0
HKD1_k127_2047896_9 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 402.0
HKD1_k127_2054661_0 PQQ enzyme repeat - - - 5.402e-211 672.0
HKD1_k127_2054661_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 366.0
HKD1_k127_2054661_2 MFP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 386.0
HKD1_k127_2054661_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002471 275.0
HKD1_k127_2054661_4 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000291 129.0
HKD1_k127_2054661_5 MacB-like periplasmic core domain - - - 0.00000000000000000000001028 107.0
HKD1_k127_2092699_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.539e-208 657.0
HKD1_k127_2092699_1 DUF218 domain - - - 0.00000000000000000000000000000000000000000000003871 178.0
HKD1_k127_2092699_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000007132 164.0
HKD1_k127_2092699_3 SnoaL-like domain - - - 0.00000000005244 69.0
HKD1_k127_2092699_4 Calcium and calcium calmodulin-dependent serine threonine-protein K08794,K13412 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004683,GO:0005488,GO:0005515,GO:0005516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009608,GO:0009877,GO:0009931,GO:0009987,GO:0010857,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.11.1,2.7.11.17 0.0003573 48.0
HKD1_k127_2115130_0 Pyruvate kinase K00873 - 2.7.1.40 1.987e-244 770.0
HKD1_k127_2115130_1 FMN-dependent dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 398.0
HKD1_k127_2115130_2 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000009909 220.0
HKD1_k127_2115130_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000002912 192.0
HKD1_k127_2115130_4 BON domain - - - 0.000000000000000000000000000000000000000000000001651 184.0
HKD1_k127_2115130_5 - - - - 0.00000000000000000000000000000000000000000004115 164.0
HKD1_k127_2115130_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001192 138.0
HKD1_k127_2115130_7 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000001859 93.0
HKD1_k127_212123_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 523.0
HKD1_k127_212123_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 467.0
HKD1_k127_212123_10 PFAM RNP-1 like RNA-binding protein - - - 0.0000001068 60.0
HKD1_k127_212123_2 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 392.0
HKD1_k127_212123_3 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000157 217.0
HKD1_k127_212123_4 Ribosomal protein L17 K02879 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000007174 184.0
HKD1_k127_212123_5 RNA recognition motif - - - 0.00000000000000000000000000006383 118.0
HKD1_k127_212123_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000001485 115.0
HKD1_k127_212123_7 methyltransferase activity - - - 0.000000000000000000000000003559 118.0
HKD1_k127_212123_8 protein kinase activity - - - 0.00000000000000000004462 102.0
HKD1_k127_212123_9 YjbR - - - 0.00000000000000001574 89.0
HKD1_k127_2143903_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1489.0
HKD1_k127_2143903_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1349.0
HKD1_k127_2143903_10 Exporters of the RND superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 495.0
HKD1_k127_2143903_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 437.0
HKD1_k127_2143903_12 Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 394.0
HKD1_k127_2143903_13 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 402.0
HKD1_k127_2143903_14 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 370.0
HKD1_k127_2143903_15 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 351.0
HKD1_k127_2143903_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 310.0
HKD1_k127_2143903_17 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 301.0
HKD1_k127_2143903_18 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 308.0
HKD1_k127_2143903_19 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 295.0
HKD1_k127_2143903_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123,K22015 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.9,1.17.99.7 0.0 1116.0
HKD1_k127_2143903_20 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007613 290.0
HKD1_k127_2143903_21 ATPase activity K02013,K05776 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008575 299.0
HKD1_k127_2143903_22 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
HKD1_k127_2143903_23 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006407 258.0
HKD1_k127_2143903_24 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001905 249.0
HKD1_k127_2143903_25 Inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000007249 237.0
HKD1_k127_2143903_26 Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
HKD1_k127_2143903_27 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000586 225.0
HKD1_k127_2143903_28 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000567 215.0
HKD1_k127_2143903_29 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.0000000000000000000000000000000000000000000000000000000000009202 217.0
HKD1_k127_2143903_3 Hydroxymethylglutaryl-coenzyme A reductase K00054 - 1.1.1.88 1.858e-313 978.0
HKD1_k127_2143903_30 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000001403 215.0
HKD1_k127_2143903_31 - - - - 0.00000000000000000000000000000000000000000000000000000001893 203.0
HKD1_k127_2143903_32 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000002302 198.0
HKD1_k127_2143903_33 TPR repeat - - - 0.00000000000000000000000000000000000000000000000005311 191.0
HKD1_k127_2143903_34 nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000007447 177.0
HKD1_k127_2143903_35 GHMP kinases N terminal domain K00938 - 2.7.4.2 0.00000000000000000000000000000000000000000002437 174.0
HKD1_k127_2143903_36 TPR repeat - - - 0.0000000000000000000000000000000000002376 152.0
HKD1_k127_2143903_37 Thioredoxin-like - - - 0.0000000000000000000000000000000009795 136.0
HKD1_k127_2143903_38 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000001392 134.0
HKD1_k127_2143903_39 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000006176 125.0
HKD1_k127_2143903_4 DNA ligase (ATP) activity K01971 - 6.5.1.1 4.603e-270 856.0
HKD1_k127_2143903_40 MlaC protein K07323 - - 0.000000000000000000000000004216 119.0
HKD1_k127_2143903_41 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000002655 115.0
HKD1_k127_2143903_42 Transcriptional regulator K07729 - - 0.00000000000000000000183 97.0
HKD1_k127_2143903_44 DnaK suppressor protein - - - 0.000000000000001337 85.0
HKD1_k127_2143903_45 - - - - 0.0000000000003146 80.0
HKD1_k127_2143903_46 Phosphorylase superfamily - - - 0.00004194 54.0
HKD1_k127_2143903_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 3.634e-231 725.0
HKD1_k127_2143903_6 Tetratricopeptide repeat - - - 3.954e-224 730.0
HKD1_k127_2143903_7 Ammonium Transporter K03320 - - 4.532e-199 630.0
HKD1_k127_2143903_8 Domain of unknown function (DUF3463) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 598.0
HKD1_k127_2143903_9 synthase K01641,K15311 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 524.0
HKD1_k127_2145732_0 Aldehyde dehydrogenase family K13922,K18119 - 1.2.1.76,1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 540.0
HKD1_k127_2145732_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005008 284.0
HKD1_k127_2145732_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003748 267.0
HKD1_k127_2145732_3 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000579 245.0
HKD1_k127_2145732_4 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000003501 218.0
HKD1_k127_2145732_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000001498 175.0
HKD1_k127_2145732_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000003875 126.0
HKD1_k127_2146608_0 Flavin containing amine oxidoreductase - - - 1.454e-215 687.0
HKD1_k127_2146608_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 500.0
HKD1_k127_2146608_2 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 485.0
HKD1_k127_2146608_3 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 446.0
HKD1_k127_2146608_4 MatE - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 474.0
HKD1_k127_2146608_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 355.0
HKD1_k127_2146608_6 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000006623 135.0
HKD1_k127_2146608_7 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000003634 124.0
HKD1_k127_2146608_9 - - - - 0.0008097 47.0
HKD1_k127_2170937_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.993e-204 660.0
HKD1_k127_2170937_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 528.0
HKD1_k127_2170937_10 membrane - - - 0.0001138 53.0
HKD1_k127_2170937_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000009155 238.0
HKD1_k127_2170937_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000002335 227.0
HKD1_k127_2170937_4 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000003987 182.0
HKD1_k127_2170937_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000001312 162.0
HKD1_k127_2170937_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000008106 139.0
HKD1_k127_2170937_8 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000001557 57.0
HKD1_k127_2170937_9 Site-specific recombinase, DNA invertase Pin - - - 0.00008835 48.0
HKD1_k127_2173715_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 3.143e-276 865.0
HKD1_k127_2173715_1 Circularly permuted ATP-grasp type 2 - - - 3.278e-256 799.0
HKD1_k127_2173715_10 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.0000000000000000000000000000000001312 135.0
HKD1_k127_2173715_11 Role in flagellar biosynthesis K02420 - - 0.00000000000000000000000000558 112.0
HKD1_k127_2173715_12 Flagellar basal body-associated protein FliL - - - 0.000000000000000000005832 100.0
HKD1_k127_2173715_13 Flagellar hook-length control protein FliK K02414 - - 0.000000000009227 77.0
HKD1_k127_2173715_14 Flagellar biosynthesis protein, FliO K02418 - - 0.00006736 54.0
HKD1_k127_2173715_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 427.0
HKD1_k127_2173715_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 310.0
HKD1_k127_2173715_4 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007851 293.0
HKD1_k127_2173715_5 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009024 288.0
HKD1_k127_2173715_6 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001755 243.0
HKD1_k127_2173715_7 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000000000000000000000000000000000006205 225.0
HKD1_k127_2173715_8 Macro domain - - - 0.00000000000000000000000000000000000000000000000000003835 193.0
HKD1_k127_2173715_9 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000004143 202.0
HKD1_k127_2200008_0 Belongs to the IlvD Edd family - - - 7.303e-211 679.0
HKD1_k127_2200008_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 493.0
HKD1_k127_2200008_10 arsenate reductase K00537 - 1.20.4.1 0.0000000000000000000000000000000000001797 148.0
HKD1_k127_2200008_11 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.00000000000000000006804 104.0
HKD1_k127_2200008_12 - - - - 0.000000008808 65.0
HKD1_k127_2200008_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
HKD1_k127_2200008_3 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 439.0
HKD1_k127_2200008_4 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 391.0
HKD1_k127_2200008_5 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 357.0
HKD1_k127_2200008_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000004754 263.0
HKD1_k127_2200008_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000593 259.0
HKD1_k127_2200008_8 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000001413 198.0
HKD1_k127_2200008_9 Sh3 type 3 domain protein K01361 - 3.4.21.96 0.000000000000000000000000000000000000001287 158.0
HKD1_k127_2226582_0 Elongation factor SelB, winged helix K03833 - - 2.472e-205 678.0
HKD1_k127_2226582_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 561.0
HKD1_k127_2226582_10 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
HKD1_k127_2226582_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000995 224.0
HKD1_k127_2226582_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001284 154.0
HKD1_k127_2226582_13 Elongation factor SelB, winged helix K03833 - - 0.00000005106 63.0
HKD1_k127_2226582_2 NADPH quinone reductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 540.0
HKD1_k127_2226582_3 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 565.0
HKD1_k127_2226582_4 alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 486.0
HKD1_k127_2226582_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 477.0
HKD1_k127_2226582_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 457.0
HKD1_k127_2226582_7 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 443.0
HKD1_k127_2226582_8 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 318.0
HKD1_k127_2226582_9 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 301.0
HKD1_k127_2236255_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.783e-210 666.0
HKD1_k127_2236255_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 554.0
HKD1_k127_2236255_10 - - - - 0.000000000000000000002434 104.0
HKD1_k127_2236255_11 Protein of unknown function (DUF1161) - - - 0.000000000000000008422 89.0
HKD1_k127_2236255_12 - - - - 0.0000000000005639 81.0
HKD1_k127_2236255_13 - - - - 0.0000000003746 68.0
HKD1_k127_2236255_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006074 249.0
HKD1_k127_2236255_3 - - - - 0.000000000000000000000000000000000000000000000000000002727 211.0
HKD1_k127_2236255_4 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000007224 206.0
HKD1_k127_2236255_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000009144 186.0
HKD1_k127_2236255_6 COG2030 Acyl dehydratase - - - 0.00000000000000000000000000000000000000000000001779 179.0
HKD1_k127_2236255_7 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.000000000000000000000000001665 119.0
HKD1_k127_2236255_8 Response regulator receiver K15012 - - 0.0000000000000000000000000405 112.0
HKD1_k127_2236255_9 - - - - 0.00000000000000000000000141 108.0
HKD1_k127_2236341_0 MacB-like periplasmic core domain - - - 6.519e-219 704.0
HKD1_k127_2236341_1 ABC-type antimicrobial peptide transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 630.0
HKD1_k127_2236341_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007511 249.0
HKD1_k127_2236341_3 MacB-like periplasmic core domain - - - 0.0000000000000000000006285 100.0
HKD1_k127_2238420_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1184.0
HKD1_k127_2238420_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1004.0
HKD1_k127_2238420_10 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 420.0
HKD1_k127_2238420_11 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 405.0
HKD1_k127_2238420_12 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 401.0
HKD1_k127_2238420_13 DNA recombination protein RmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 403.0
HKD1_k127_2238420_14 Psort location Cytoplasmic, score 8.96 K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 372.0
HKD1_k127_2238420_15 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 364.0
HKD1_k127_2238420_16 methyltransferase K10218 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 317.0
HKD1_k127_2238420_17 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 322.0
HKD1_k127_2238420_18 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 299.0
HKD1_k127_2238420_19 PFAM Helix-turn-helix, type 11 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001239 282.0
HKD1_k127_2238420_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.207e-271 844.0
HKD1_k127_2238420_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006154 263.0
HKD1_k127_2238420_21 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 254.0
HKD1_k127_2238420_22 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000001412 252.0
HKD1_k127_2238420_23 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000003322 248.0
HKD1_k127_2238420_24 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000005658 235.0
HKD1_k127_2238420_25 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000001803 223.0
HKD1_k127_2238420_26 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000008703 195.0
HKD1_k127_2238420_27 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000008017 176.0
HKD1_k127_2238420_28 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000003372 157.0
HKD1_k127_2238420_29 Ion channel - - - 0.000000000000000000000000000000000001905 145.0
HKD1_k127_2238420_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 508.0
HKD1_k127_2238420_30 protein import - - - 0.000000000000000000000000004887 123.0
HKD1_k127_2238420_31 - - - - 0.000000000000000000000000005622 120.0
HKD1_k127_2238420_32 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000005096 81.0
HKD1_k127_2238420_33 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.00000000000001563 77.0
HKD1_k127_2238420_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 498.0
HKD1_k127_2238420_5 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 485.0
HKD1_k127_2238420_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 472.0
HKD1_k127_2238420_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 467.0
HKD1_k127_2238420_8 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 423.0
HKD1_k127_2238420_9 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 421.0
HKD1_k127_2263647_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1013.0
HKD1_k127_2263647_1 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 552.0
HKD1_k127_2263647_2 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 528.0
HKD1_k127_2263647_3 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000001141 172.0
HKD1_k127_2263647_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000003478 155.0
HKD1_k127_2274234_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5e-324 1003.0
HKD1_k127_2274234_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.468e-246 772.0
HKD1_k127_2274234_10 - - - - 0.0000000000000000002129 90.0
HKD1_k127_2274234_11 - - - - 0.0000000000000003216 85.0
HKD1_k127_2274234_12 TonB dependent receptor - - - 0.0000001146 59.0
HKD1_k127_2274234_13 - - - - 0.0003132 49.0
HKD1_k127_2274234_2 FAD binding domain - - - 6.965e-194 618.0
HKD1_k127_2274234_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 569.0
HKD1_k127_2274234_4 Uncharacterised MFS-type transporter YbfB K05548,K05819,K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 463.0
HKD1_k127_2274234_5 - - - - 0.000000000000000000000000000004923 127.0
HKD1_k127_2274234_6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000005767 111.0
HKD1_k127_2274234_7 - - - - 0.0000000000000000000000001209 113.0
HKD1_k127_2274234_8 - - - - 0.00000000000000000000009799 110.0
HKD1_k127_2274234_9 - - - - 0.0000000000000000000007383 104.0
HKD1_k127_2295631_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 314.0
HKD1_k127_2295631_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
HKD1_k127_2295631_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000001723 147.0
HKD1_k127_2295631_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000006616 135.0
HKD1_k127_2295631_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000002949 114.0
HKD1_k127_2295631_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000004102 106.0
HKD1_k127_2295631_14 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000009534 83.0
HKD1_k127_2295631_15 Carboxypeptidase regulatory-like domain - - - 0.000000001871 59.0
HKD1_k127_2295631_16 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000498 65.0
HKD1_k127_2295631_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001797 250.0
HKD1_k127_2295631_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000002347 248.0
HKD1_k127_2295631_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000011 228.0
HKD1_k127_2295631_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000001269 226.0
HKD1_k127_2295631_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003151 208.0
HKD1_k127_2295631_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000001659 169.0
HKD1_k127_2295631_8 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000006639 161.0
HKD1_k127_2295631_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000001687 157.0
HKD1_k127_2312594_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1116.0
HKD1_k127_2312594_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 7.052e-274 856.0
HKD1_k127_2312594_10 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 451.0
HKD1_k127_2312594_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 422.0
HKD1_k127_2312594_12 transporter, permease K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 411.0
HKD1_k127_2312594_13 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 406.0
HKD1_k127_2312594_14 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 388.0
HKD1_k127_2312594_15 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 366.0
HKD1_k127_2312594_16 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 349.0
HKD1_k127_2312594_17 signal transduction histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 336.0
HKD1_k127_2312594_18 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 317.0
HKD1_k127_2312594_19 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 301.0
HKD1_k127_2312594_2 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 1.047e-238 745.0
HKD1_k127_2312594_20 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002681 281.0
HKD1_k127_2312594_21 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007998 291.0
HKD1_k127_2312594_22 ABC transporter K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000004632 267.0
HKD1_k127_2312594_23 COG1668 ABC-type Na efflux pump, permease component K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003998 262.0
HKD1_k127_2312594_24 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000001091 255.0
HKD1_k127_2312594_25 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000006349 240.0
HKD1_k127_2312594_26 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000007201 236.0
HKD1_k127_2312594_27 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000003043 218.0
HKD1_k127_2312594_28 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000005665 199.0
HKD1_k127_2312594_29 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000002523 160.0
HKD1_k127_2312594_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.245e-224 704.0
HKD1_k127_2312594_30 cytochrome - - - 0.00000000000000000000000000000000000000004271 160.0
HKD1_k127_2312594_31 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000001153 155.0
HKD1_k127_2312594_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000008356 145.0
HKD1_k127_2312594_33 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000001173 113.0
HKD1_k127_2312594_34 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000006171 98.0
HKD1_k127_2312594_35 Putative diguanylate phosphodiesterase - - - 0.0000000000000000002165 96.0
HKD1_k127_2312594_36 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002777 80.0
HKD1_k127_2312594_37 Domain of unknown function (DUF4124) - - - 0.000000000000001889 83.0
HKD1_k127_2312594_38 atp synthase K02116 GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000001414 68.0
HKD1_k127_2312594_4 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 2.613e-205 653.0
HKD1_k127_2312594_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 611.0
HKD1_k127_2312594_6 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 618.0
HKD1_k127_2312594_7 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 593.0
HKD1_k127_2312594_8 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 559.0
HKD1_k127_2312594_9 Belongs to the dihydroorotate dehydrogenase family K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 480.0
HKD1_k127_2345689_0 Belongs to the Orn Lys Arg decarboxylase class-II family K00928,K12526 - 2.7.2.4,4.1.1.20 8.373e-299 940.0
HKD1_k127_2345689_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.105e-254 796.0
HKD1_k127_2345689_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000279 242.0
HKD1_k127_2345689_11 - - - - 0.00000000000000000000000000000000000000000004299 164.0
HKD1_k127_2345689_12 COG4635 Flavodoxin K00230 - 1.3.5.3 0.0000000000000000000000000000000000000002195 157.0
HKD1_k127_2345689_13 - - - - 0.0000000000000000000000000000000005294 148.0
HKD1_k127_2345689_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000006875 123.0
HKD1_k127_2345689_15 protein, YerC YecD - - - 0.00000000000000000000000001052 112.0
HKD1_k127_2345689_16 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000000000000000000005354 102.0
HKD1_k127_2345689_17 Type II secretory pathway component ExeA K02450,K12283 - - 0.000000000000000003554 98.0
HKD1_k127_2345689_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00004824 51.0
HKD1_k127_2345689_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 497.0
HKD1_k127_2345689_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 431.0
HKD1_k127_2345689_4 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 411.0
HKD1_k127_2345689_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 377.0
HKD1_k127_2345689_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 330.0
HKD1_k127_2345689_7 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 324.0
HKD1_k127_2345689_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 317.0
HKD1_k127_2345689_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000005829 238.0
HKD1_k127_2356787_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 8.062e-222 713.0
HKD1_k127_2356787_1 'PFAM Alpha amylase, catalytic K00690 GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.7 1.026e-209 662.0
HKD1_k127_2356787_10 Transcriptional regulator sugar kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 315.0
HKD1_k127_2356787_11 COG0477 Permeases of the major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001187 258.0
HKD1_k127_2356787_12 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000001594 239.0
HKD1_k127_2356787_13 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000001104 222.0
HKD1_k127_2356787_14 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000001113 224.0
HKD1_k127_2356787_15 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000471 192.0
HKD1_k127_2356787_16 transcriptional regulator - - - 0.0000000000000000000000000000001483 127.0
HKD1_k127_2356787_17 protein conserved in bacteria K01790 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 0.0000000000000000000001029 102.0
HKD1_k127_2356787_18 Sugar (and other) transporter - - - 0.0000000000003462 72.0
HKD1_k127_2356787_19 Prolyl oligopeptidase family - - - 0.0008566 51.0
HKD1_k127_2356787_2 Feruloyl esterase K21105 - 3.1.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 560.0
HKD1_k127_2356787_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 470.0
HKD1_k127_2356787_4 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 469.0
HKD1_k127_2356787_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
HKD1_k127_2356787_7 periplasmic binding protein LacI transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 347.0
HKD1_k127_2356787_8 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 344.0
HKD1_k127_2356787_9 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 337.0
HKD1_k127_236749_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 433.0
HKD1_k127_236749_1 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 316.0
HKD1_k127_236749_2 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000003291 208.0
HKD1_k127_236749_3 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000002146 132.0
HKD1_k127_236749_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000002453 132.0
HKD1_k127_236749_5 - - - - 0.0000000000000000000000119 108.0
HKD1_k127_2377594_0 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 384.0
HKD1_k127_2377594_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 395.0
HKD1_k127_2377594_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 377.0
HKD1_k127_2377594_3 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 292.0
HKD1_k127_2377594_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004698 270.0
HKD1_k127_2377594_5 Glutathione S-transferase, N-terminal domain - - - 0.00000000000001982 79.0
HKD1_k127_2377594_6 membrane - - - 0.00000009913 58.0
HKD1_k127_2377594_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00002496 49.0
HKD1_k127_2435792_0 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 508.0
HKD1_k127_2435792_1 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 462.0
HKD1_k127_2435792_2 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 408.0
HKD1_k127_2435792_3 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 307.0
HKD1_k127_2435792_4 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
HKD1_k127_2435792_5 - - - - 0.000000000000000000000000000000000000000000000003182 186.0
HKD1_k127_2435792_6 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000001701 178.0
HKD1_k127_2435792_7 TonB dependent receptor K02014 - - 0.00000000000000000000000105 112.0
HKD1_k127_2474366_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1454.0
HKD1_k127_2474366_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 324.0
HKD1_k127_2474366_2 outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 300.0
HKD1_k127_2603692_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1202.0
HKD1_k127_2603692_1 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 601.0
HKD1_k127_2603692_10 TPM domain K08988 - - 0.00000000000000000000000000000000000000003692 162.0
HKD1_k127_2603692_11 Domain of unknown function (DUF4185) - - - 0.0000000000000000000000000000000002887 150.0
HKD1_k127_2603692_13 histone acetyltransferase HPA2 and related acetyltransferases - GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.0000000000000000004135 98.0
HKD1_k127_2603692_2 alcohol dehydrogenase K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 530.0
HKD1_k127_2603692_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 297.0
HKD1_k127_2603692_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 297.0
HKD1_k127_2603692_6 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000001481 248.0
HKD1_k127_2603692_7 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006048 233.0
HKD1_k127_2603692_8 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000002605 213.0
HKD1_k127_2603692_9 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000001617 188.0
HKD1_k127_2636264_0 Major Facilitator Superfamily - - - 2.35e-255 799.0
HKD1_k127_2636264_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 352.0
HKD1_k127_2636264_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 326.0
HKD1_k127_2636264_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000001982 257.0
HKD1_k127_2636264_4 Haem-degrading - - - 0.00000000000000000000000000000000000005533 150.0
HKD1_k127_270291_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1065.0
HKD1_k127_270291_1 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 2.087e-235 735.0
HKD1_k127_270291_2 PFAM glycine cleavage T protein (aminomethyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000001198 225.0
HKD1_k127_270291_3 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000002616 72.0
HKD1_k127_2806946_0 Peptidase M16 - - - 0.0 1041.0
HKD1_k127_2806946_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1038.0
HKD1_k127_2806946_10 SpoVR like protein K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 606.0
HKD1_k127_2806946_11 PFAM Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 550.0
HKD1_k127_2806946_12 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 527.0
HKD1_k127_2806946_13 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 520.0
HKD1_k127_2806946_14 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 485.0
HKD1_k127_2806946_15 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 460.0
HKD1_k127_2806946_16 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 459.0
HKD1_k127_2806946_17 Aminotransferase class-V K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 474.0
HKD1_k127_2806946_18 TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 447.0
HKD1_k127_2806946_19 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 462.0
HKD1_k127_2806946_2 PFAM PrkA AAA K07180 - - 2.543e-302 940.0
HKD1_k127_2806946_20 Transcriptional regulator K06714,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 445.0
HKD1_k127_2806946_21 Sigma-54 interaction domain K03974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 426.0
HKD1_k127_2806946_22 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 430.0
HKD1_k127_2806946_23 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 418.0
HKD1_k127_2806946_24 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 431.0
HKD1_k127_2806946_25 Reductase C-terminal K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 415.0
HKD1_k127_2806946_26 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 409.0
HKD1_k127_2806946_27 COG1131 ABC-type multidrug transport system, ATPase component K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 407.0
HKD1_k127_2806946_28 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 394.0
HKD1_k127_2806946_29 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 393.0
HKD1_k127_2806946_3 Domain of unknown function (DUF1974) K06445 - - 5.832e-282 888.0
HKD1_k127_2806946_30 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 391.0
HKD1_k127_2806946_31 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 388.0
HKD1_k127_2806946_32 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 358.0
HKD1_k127_2806946_33 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 318.0
HKD1_k127_2806946_34 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 310.0
HKD1_k127_2806946_35 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 301.0
HKD1_k127_2806946_36 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 308.0
HKD1_k127_2806946_37 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 292.0
HKD1_k127_2806946_38 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005842 294.0
HKD1_k127_2806946_39 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009284 263.0
HKD1_k127_2806946_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 1.212e-281 876.0
HKD1_k127_2806946_40 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001469 265.0
HKD1_k127_2806946_41 Diguanylate cyclase phosphodiesterase with PAS PAC K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003172 280.0
HKD1_k127_2806946_42 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000006072 259.0
HKD1_k127_2806946_43 Phospholipase/Carboxylesterase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000001646 251.0
HKD1_k127_2806946_44 Two component transcriptional regulator, winged helix family K07662,K19610 GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010810,GO:0019219,GO:0019222,GO:0030155,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
HKD1_k127_2806946_45 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004098 241.0
HKD1_k127_2806946_46 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000001156 233.0
HKD1_k127_2806946_47 PFAM PspA IM30 family protein K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000001601 233.0
HKD1_k127_2806946_48 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000001124 231.0
HKD1_k127_2806946_49 PFAM cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000002636 216.0
HKD1_k127_2806946_5 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 1.741e-265 829.0
HKD1_k127_2806946_50 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000003978 189.0
HKD1_k127_2806946_51 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000005045 187.0
HKD1_k127_2806946_52 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000002177 200.0
HKD1_k127_2806946_53 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000063 185.0
HKD1_k127_2806946_54 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000003381 185.0
HKD1_k127_2806946_55 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000007397 183.0
HKD1_k127_2806946_56 - - - - 0.000000000000000000000000000000000000000000003438 171.0
HKD1_k127_2806946_57 proteolysis - - - 0.000000000000000000000000000000000000000001431 168.0
HKD1_k127_2806946_58 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000003992 162.0
HKD1_k127_2806946_59 - - - - 0.0000000000000000000000000000000004391 140.0
HKD1_k127_2806946_6 transporter - - - 4.129e-263 841.0
HKD1_k127_2806946_60 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000003198 134.0
HKD1_k127_2806946_61 Protein of unknown function (DUF3775) - - - 0.00000000000000000000000001799 112.0
HKD1_k127_2806946_62 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000007573 98.0
HKD1_k127_2806946_63 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000007583 102.0
HKD1_k127_2806946_64 - - - - 0.000000000000000001063 91.0
HKD1_k127_2806946_65 Phage shock protein B K03970 - - 0.000000000000000004623 86.0
HKD1_k127_2806946_66 phage shock protein C K03973 - - 0.0000000000000001583 84.0
HKD1_k127_2806946_67 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000001723 72.0
HKD1_k127_2806946_68 - - - - 0.0000000006347 72.0
HKD1_k127_2806946_69 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03425 GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000007844 62.0
HKD1_k127_2806946_7 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.617e-250 788.0
HKD1_k127_2806946_70 - - - - 0.000000009253 64.0
HKD1_k127_2806946_71 Protein of unknown function (DUF2845) - - - 0.000000009939 64.0
HKD1_k127_2806946_72 SH3 domain protein K07184 - - 0.000004233 58.0
HKD1_k127_2806946_74 Type II secretion system protein B K02451 - - 0.00002599 55.0
HKD1_k127_2806946_76 - - - - 0.0001879 47.0
HKD1_k127_2806946_8 Pyruvate kinase K00873 - 2.7.1.40 1.242e-227 721.0
HKD1_k127_2806946_9 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 1.409e-208 660.0
HKD1_k127_288576_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 412.0
HKD1_k127_288576_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000001427 267.0
HKD1_k127_288576_3 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000004901 210.0
HKD1_k127_288576_4 Glutathione peroxidase K02199 - - 0.000000000000000000000000000000001259 140.0
HKD1_k127_288576_5 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000004042 130.0
HKD1_k127_2935120_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.233e-219 690.0
HKD1_k127_2935120_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000973 220.0
HKD1_k127_2935120_2 Colicin v production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.00000000000000000000000001761 116.0
HKD1_k127_2935120_3 PFAM Sporulation K03749 - - 0.00000000008467 70.0
HKD1_k127_2954576_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 4.711e-202 636.0
HKD1_k127_2954576_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 505.0
HKD1_k127_2954576_10 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002269 287.0
HKD1_k127_2954576_11 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001362 259.0
HKD1_k127_2954576_12 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003616 250.0
HKD1_k127_2954576_13 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000002182 236.0
HKD1_k127_2954576_14 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000002008 249.0
HKD1_k127_2954576_15 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000004103 218.0
HKD1_k127_2954576_16 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000001015 154.0
HKD1_k127_2954576_17 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000002465 123.0
HKD1_k127_2954576_18 Domain of unknown function (DUF4124) - - - 0.0000000000000000000004723 104.0
HKD1_k127_2954576_19 there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc K02913 - - 0.0000000000000000002851 87.0
HKD1_k127_2954576_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 460.0
HKD1_k127_2954576_3 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 402.0
HKD1_k127_2954576_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 359.0
HKD1_k127_2954576_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 331.0
HKD1_k127_2954576_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 325.0
HKD1_k127_2954576_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 303.0
HKD1_k127_2954576_8 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 300.0
HKD1_k127_2954576_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001093 276.0
HKD1_k127_3022442_0 Major Facilitator Superfamily K02429 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 530.0
HKD1_k127_3022442_1 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 470.0
HKD1_k127_3022442_10 AntiSigma factor - - - 0.00000000000000000000003694 114.0
HKD1_k127_3022442_2 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 461.0
HKD1_k127_3022442_3 DNA polymerase type-B family K02336 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 349.0
HKD1_k127_3022442_4 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 332.0
HKD1_k127_3022442_5 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 299.0
HKD1_k127_3022442_6 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000002357 215.0
HKD1_k127_3022442_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000004029 178.0
HKD1_k127_3022442_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000864 183.0
HKD1_k127_3022442_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000003627 168.0
HKD1_k127_3059746_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 580.0
HKD1_k127_3059746_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 540.0
HKD1_k127_3059746_10 - - - - 0.0000000000000000000000000000012 134.0
HKD1_k127_3059746_11 - - - - 0.0000000000000000000001753 105.0
HKD1_k127_3059746_12 ABC-2 family transporter protein - - - 0.00000000000000000001131 107.0
HKD1_k127_3059746_13 - - - - 0.000000000000000000579 95.0
HKD1_k127_3059746_14 Bacterial protein of unknown function (DUF945) - - - 0.00000000000000002672 96.0
HKD1_k127_3059746_15 - - - - 0.0000000000000001063 91.0
HKD1_k127_3059746_16 Calcineurin-like phosphoesterase K07098 - - 0.0000000000001616 72.0
HKD1_k127_3059746_17 - - - - 0.0004132 43.0
HKD1_k127_3059746_18 Glyoxalase-like domain - - - 0.0005956 51.0
HKD1_k127_3059746_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 470.0
HKD1_k127_3059746_3 Glucose / Sorbosone dehydrogenase K00117,K21430 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 417.0
HKD1_k127_3059746_4 ABC-type multidrug transport system, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 343.0
HKD1_k127_3059746_5 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003122 270.0
HKD1_k127_3059746_6 - - - - 0.00000000000000000000000000000000000000000000000000002741 197.0
HKD1_k127_3059746_7 Putative FMN-binding domain - - - 0.0000000000000000000000000000000000000000000000000003746 194.0
HKD1_k127_3059746_8 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000006211 150.0
HKD1_k127_3059746_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000003717 150.0
HKD1_k127_3063215_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 443.0
HKD1_k127_3063215_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001881 264.0
HKD1_k127_3063215_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000002322 242.0
HKD1_k127_3063215_3 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000002096 158.0
HKD1_k127_3128373_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 489.0
HKD1_k127_3128373_1 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 466.0
HKD1_k127_3128373_10 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000004608 196.0
HKD1_k127_3128373_11 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000000006991 183.0
HKD1_k127_3128373_12 Conserved TM helix - - - 0.000000000000000000000000000000000000000002019 173.0
HKD1_k127_3128373_13 MgtE intracellular N domain - - - 0.000000000000000000000001737 115.0
HKD1_k127_3128373_14 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000127 93.0
HKD1_k127_3128373_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 412.0
HKD1_k127_3128373_3 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 403.0
HKD1_k127_3128373_4 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 372.0
HKD1_k127_3128373_5 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 349.0
HKD1_k127_3128373_6 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 336.0
HKD1_k127_3128373_7 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007368 274.0
HKD1_k127_3128373_8 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
HKD1_k127_3128373_9 involved in outer membrane biogenesis K07289 - - 0.000000000000000000000000000000000000000000000000000000000003246 239.0
HKD1_k127_3132597_0 secondary active sulfate transmembrane transporter activity K03321 - - 1.049e-271 847.0
HKD1_k127_3132597_1 Sodium/hydrogen exchanger family K03316 - - 3.966e-202 644.0
HKD1_k127_3132597_10 PFAM OmpA domain protein transmembrane region-containing protein K03286 - - 0.0000007086 58.0
HKD1_k127_3132597_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 451.0
HKD1_k127_3132597_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 455.0
HKD1_k127_3132597_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003415 258.0
HKD1_k127_3132597_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000002267 183.0
HKD1_k127_3132597_6 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000000000000000000000000000000000003518 147.0
HKD1_k127_3132597_7 CsbD-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000007096 100.0
HKD1_k127_3132597_8 Transcriptional regulatory protein, C terminal - - - 0.00000000000000001225 87.0
HKD1_k127_3132597_9 UPF0391 membrane protein - - - 0.000000000000001725 78.0
HKD1_k127_3147549_0 AcrB/AcrD/AcrF family - - - 0.0 1265.0
HKD1_k127_3147549_1 DNA topological change K03168 - 5.99.1.2 1.859e-200 651.0
HKD1_k127_3147549_10 Ankyrin repeat domain protein - - - 0.000000000000000000000000000003822 137.0
HKD1_k127_3147549_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000002919 84.0
HKD1_k127_3147549_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 402.0
HKD1_k127_3147549_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 391.0
HKD1_k127_3147549_4 Transcriptional regulatory protein, C terminal K07669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003476 244.0
HKD1_k127_3147549_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000002418 177.0
HKD1_k127_3147549_6 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000002705 190.0
HKD1_k127_3147549_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000001965 176.0
HKD1_k127_3147549_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000002167 164.0
HKD1_k127_3147549_9 - - - - 0.00000000000000000000000000000000000004608 147.0
HKD1_k127_3153526_0 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 340.0
HKD1_k127_3153526_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002449 245.0
HKD1_k127_3153526_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004809 250.0
HKD1_k127_3153526_3 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000005764 130.0
HKD1_k127_3153526_5 Receptor K02014,K16087 - - 0.000000000000000039 81.0
HKD1_k127_3153526_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000009368 86.0
HKD1_k127_3153526_7 - - - - 0.0000000000000001264 91.0
HKD1_k127_3167029_0 PUA-like domain K00958 - 2.7.7.4 1.517e-275 857.0
HKD1_k127_3167029_1 Sulfite reductase K00381 - 1.8.1.2 4.523e-227 717.0
HKD1_k127_3167029_10 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 308.0
HKD1_k127_3167029_11 D-arabinono-1,4-lactone oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004358 291.0
HKD1_k127_3167029_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003472 280.0
HKD1_k127_3167029_13 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001004 252.0
HKD1_k127_3167029_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000008556 232.0
HKD1_k127_3167029_15 protein conserved in bacteria K09958 - - 0.0000000000000000000000000000000000000000000000000000000000004758 217.0
HKD1_k127_3167029_16 Molybdopterin binding K17225 - - 0.000000000000000000000000000000000000000000000000000000001534 210.0
HKD1_k127_3167029_17 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000001128 185.0
HKD1_k127_3167029_18 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000003105 178.0
HKD1_k127_3167029_19 - - - - 0.000000000001924 78.0
HKD1_k127_3167029_2 MFS/sugar transport protein K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 511.0
HKD1_k127_3167029_20 Protein of unknown function (DUF2849) - - - 0.00000000001109 71.0
HKD1_k127_3167029_21 - - - - 0.00000000007622 71.0
HKD1_k127_3167029_3 phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 509.0
HKD1_k127_3167029_4 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 448.0
HKD1_k127_3167029_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
HKD1_k127_3167029_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 374.0
HKD1_k127_3167029_7 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 370.0
HKD1_k127_3167029_8 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 377.0
HKD1_k127_3167029_9 malonyl CoA-acyl carrier protein transacylase K00645,K13935 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 333.0
HKD1_k127_3186216_0 Acetyl-coenzyme A synthetase N-terminus - - - 2.296e-252 797.0
HKD1_k127_3186216_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 8.435e-209 664.0
HKD1_k127_3186216_10 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 327.0
HKD1_k127_3186216_11 Membrane protein TerC, possibly involved in tellurium resistance - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 302.0
HKD1_k127_3186216_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 302.0
HKD1_k127_3186216_13 carbonate dehydratase activity K01674 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008614 282.0
HKD1_k127_3186216_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001408 231.0
HKD1_k127_3186216_15 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000008595 222.0
HKD1_k127_3186216_16 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000001272 221.0
HKD1_k127_3186216_17 type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000006819 182.0
HKD1_k127_3186216_18 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.000000000000000000000000000000000000000005019 156.0
HKD1_k127_3186216_19 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000849 161.0
HKD1_k127_3186216_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 592.0
HKD1_k127_3186216_20 Reduces the stability of FtsZ polymers in the presence of ATP K06916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - 0.0000000000000000000000000000000002191 140.0
HKD1_k127_3186216_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000002139 138.0
HKD1_k127_3186216_22 protein conserved in bacteria - - - 0.00000000000000000000000000000033 132.0
HKD1_k127_3186216_23 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000324 122.0
HKD1_k127_3186216_24 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000006582 108.0
HKD1_k127_3186216_25 DoxX K15977 - - 0.0000000000000000000001159 107.0
HKD1_k127_3186216_26 PDZ domain - - - 0.0000000000000001842 91.0
HKD1_k127_3186216_27 Domain of unknown function (DUF4115) K15539 - - 0.00000000001338 76.0
HKD1_k127_3186216_28 HAD-hyrolase-like K07025 - - 0.00000000001965 77.0
HKD1_k127_3186216_29 NifU-like N terminal domain - - - 0.00000000002061 69.0
HKD1_k127_3186216_3 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 496.0
HKD1_k127_3186216_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 497.0
HKD1_k127_3186216_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 427.0
HKD1_k127_3186216_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 425.0
HKD1_k127_3186216_7 essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 390.0
HKD1_k127_3186216_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 396.0
HKD1_k127_3186216_9 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 355.0
HKD1_k127_3202237_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 2.369e-268 841.0
HKD1_k127_3202237_1 DNA topological change K03168 - 5.99.1.2 1.215e-235 754.0
HKD1_k127_3202237_10 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 417.0
HKD1_k127_3202237_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 404.0
HKD1_k127_3202237_12 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 360.0
HKD1_k127_3202237_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 334.0
HKD1_k127_3202237_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 319.0
HKD1_k127_3202237_15 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 324.0
HKD1_k127_3202237_16 bacteriocin export ABC transporter, lactococcin 972 group K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 292.0
HKD1_k127_3202237_17 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 295.0
HKD1_k127_3202237_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 275.0
HKD1_k127_3202237_19 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001018 254.0
HKD1_k127_3202237_2 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 1.107e-215 693.0
HKD1_k127_3202237_20 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001029 252.0
HKD1_k127_3202237_21 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001072 254.0
HKD1_k127_3202237_22 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001176 249.0
HKD1_k127_3202237_23 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000001588 234.0
HKD1_k127_3202237_24 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000001616 197.0
HKD1_k127_3202237_25 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000001731 179.0
HKD1_k127_3202237_26 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000001438 168.0
HKD1_k127_3202237_27 methyltransferase - - - 0.0000000000000000000000000000000000000001172 157.0
HKD1_k127_3202237_28 GntR family transcriptional regulator K07979 - - 0.00000000000000000000000000001235 123.0
HKD1_k127_3202237_29 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000006425 126.0
HKD1_k127_3202237_3 PQQ-like domain K00117 - 1.1.5.2 3.937e-211 675.0
HKD1_k127_3202237_30 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.00000000000000002355 94.0
HKD1_k127_3202237_31 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000007195 81.0
HKD1_k127_3202237_32 EF-hand domain pair - - - 0.0000001953 64.0
HKD1_k127_3202237_33 Bacterial virulence protein (VirJ) - - - 0.000003124 58.0
HKD1_k127_3202237_34 Tetratricopeptide repeat - - - 0.00008002 55.0
HKD1_k127_3202237_4 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 596.0
HKD1_k127_3202237_5 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 530.0
HKD1_k127_3202237_6 Multicopper oxidase K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 506.0
HKD1_k127_3202237_7 Amino acid permease K11735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 494.0
HKD1_k127_3202237_8 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 446.0
HKD1_k127_3202237_9 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 452.0
HKD1_k127_3238466_0 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 374.0
HKD1_k127_3238466_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003045 286.0
HKD1_k127_3238466_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002225 255.0
HKD1_k127_3238466_3 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002082 253.0
HKD1_k127_3241018_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.675e-203 642.0
HKD1_k127_3241018_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 567.0
HKD1_k127_3241018_2 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002261 284.0
HKD1_k127_3241018_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003193 285.0
HKD1_k127_3241018_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000004059 165.0
HKD1_k127_3241018_5 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000001648 160.0
HKD1_k127_3241018_6 protein acetylation - - - 0.000000000000009863 81.0
HKD1_k127_3247336_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.617e-318 991.0
HKD1_k127_3247336_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.606e-248 777.0
HKD1_k127_3247336_10 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000002617 140.0
HKD1_k127_3247336_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000002569 85.0
HKD1_k127_3247336_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 5.665e-234 755.0
HKD1_k127_3247336_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 403.0
HKD1_k127_3247336_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006547 252.0
HKD1_k127_3247336_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
HKD1_k127_3247336_6 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000009263 218.0
HKD1_k127_3247336_7 universal stress protein K14055 - - 0.00000000000000000000000000000000000000000000000007841 189.0
HKD1_k127_3247336_8 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000002175 161.0
HKD1_k127_3247336_9 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000003613 142.0
HKD1_k127_329599_0 Peptidase C39 family K13409 - - 1.018e-258 819.0
HKD1_k127_329599_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 612.0
HKD1_k127_329599_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 304.0
HKD1_k127_329599_11 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 319.0
HKD1_k127_329599_12 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000329 306.0
HKD1_k127_329599_13 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001692 243.0
HKD1_k127_329599_14 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000183 203.0
HKD1_k127_329599_15 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000001663 203.0
HKD1_k127_329599_17 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000001646 140.0
HKD1_k127_329599_18 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000006346 137.0
HKD1_k127_329599_19 Adenylate cyclase - - - 0.000000000000000000000000000000001622 147.0
HKD1_k127_329599_2 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 564.0
HKD1_k127_329599_20 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000009142 139.0
HKD1_k127_329599_21 - - - - 0.000000000000000000000000000005677 135.0
HKD1_k127_329599_22 Phospholipid methyltransferase - - - 0.0000000000000000000001102 105.0
HKD1_k127_329599_23 Protein of unknown function (DUF2905) - - - 0.000000000000000000002547 94.0
HKD1_k127_329599_24 Beta-lactamase - - - 0.0000000005257 72.0
HKD1_k127_329599_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 520.0
HKD1_k127_329599_4 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 503.0
HKD1_k127_329599_5 chorismate binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 501.0
HKD1_k127_329599_6 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 420.0
HKD1_k127_329599_7 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 405.0
HKD1_k127_329599_9 HlyD family secretion protein K13408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 336.0
HKD1_k127_3308311_0 - - - - 1.598e-212 682.0
HKD1_k127_3308311_1 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 465.0
HKD1_k127_3308311_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 376.0
HKD1_k127_3308311_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 367.0
HKD1_k127_3308311_4 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000004846 235.0
HKD1_k127_3308311_5 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000000000000000000000000000000000000000000004338 204.0
HKD1_k127_3308311_6 ABC transporter K02003 - - 0.00000000000000000003369 91.0
HKD1_k127_3308399_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 468.0
HKD1_k127_3308399_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 417.0
HKD1_k127_3308399_10 cytochrome - - - 0.00000000000000133 91.0
HKD1_k127_3308399_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000001778 72.0
HKD1_k127_3308399_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005301 287.0
HKD1_k127_3308399_3 helix-turn-helix- domain containing protein, AraC type K13653 - - 0.000000000000000000000000000000000000000000000000000003539 203.0
HKD1_k127_3308399_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000004231 209.0
HKD1_k127_3308399_5 helix-turn-helix- domain containing protein, AraC type K13653 - - 0.000000000000000000000000000000000000000000000000000183 195.0
HKD1_k127_3308399_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000005536 194.0
HKD1_k127_3308399_7 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000002662 123.0
HKD1_k127_3308399_8 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 - 2.4.1.250 0.000000000000000000004395 106.0
HKD1_k127_3308399_9 ABC transporter K02003 - - 0.00000000000000000002333 91.0
HKD1_k127_3308796_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 398.0
HKD1_k127_3308796_1 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003659 287.0
HKD1_k127_3308796_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007869 273.0
HKD1_k127_3308796_3 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000001565 133.0
HKD1_k127_3308796_4 - - - - 0.000000000000000000000000003135 121.0
HKD1_k127_3308796_5 Protein of unknown function (DUF2802) - - - 0.0001312 50.0
HKD1_k127_3312876_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1191.0
HKD1_k127_3312876_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 524.0
HKD1_k127_3312876_10 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000007643 130.0
HKD1_k127_3312876_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000004567 126.0
HKD1_k127_3312876_12 GtrA-like protein - - - 0.00000000000000000001469 97.0
HKD1_k127_3312876_13 COG2931 RTX toxins and related Ca2 -binding proteins K11005 - - 0.0000000000000000001286 99.0
HKD1_k127_3312876_14 - - - - 0.0000000000000000002874 93.0
HKD1_k127_3312876_15 PRC-barrel domain - - - 0.00000000000000001719 95.0
HKD1_k127_3312876_16 - - - - 0.000000000000001324 87.0
HKD1_k127_3312876_17 - - - - 0.0000000000004646 81.0
HKD1_k127_3312876_18 Forkhead associated domain - - - 0.000000000583 71.0
HKD1_k127_3312876_19 - - - - 0.0006186 51.0
HKD1_k127_3312876_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 492.0
HKD1_k127_3312876_3 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 313.0
HKD1_k127_3312876_4 Platelet-activating factor acetylhydrolase, plasma intracellular isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 301.0
HKD1_k127_3312876_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003518 283.0
HKD1_k127_3312876_6 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009466 263.0
HKD1_k127_3312876_7 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000005824 243.0
HKD1_k127_3312876_8 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000000000008261 169.0
HKD1_k127_3312876_9 - - - - 0.000000000000000000000000000000000002184 151.0
HKD1_k127_335321_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 610.0
HKD1_k127_335321_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 556.0
HKD1_k127_335321_10 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000008098 223.0
HKD1_k127_335321_11 phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000001542 213.0
HKD1_k127_335321_12 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000002564 218.0
HKD1_k127_335321_13 DSBA-like thioredoxin domain K07396 - - 0.00000000000000000000000000000000000000000000000000000004295 203.0
HKD1_k127_335321_14 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000009818 185.0
HKD1_k127_335321_15 Hemerythrin - - - 0.0000000000000000000000000000000000000002563 156.0
HKD1_k127_335321_16 PFAM DGPFAETKE family protein - - - 0.0000000000000000000000000000000000000005318 154.0
HKD1_k127_335321_17 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000001572 151.0
HKD1_k127_335321_19 Protein of unknown function (DUF1289) - - - 0.000000000000003941 78.0
HKD1_k127_335321_2 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 512.0
HKD1_k127_335321_20 - - - - 0.000000000000004139 81.0
HKD1_k127_335321_21 - - - - 0.0000000000003667 75.0
HKD1_k127_335321_22 Pilus assembly protein PilX K02673 - - 0.00000000001319 79.0
HKD1_k127_335321_23 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.00001578 52.0
HKD1_k127_335321_3 Retinal pigment epithelial membrane protein K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 383.0
HKD1_k127_335321_4 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 372.0
HKD1_k127_335321_5 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000535 280.0
HKD1_k127_335321_6 Belongs to the HpcH HpaI aldolase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000009598 257.0
HKD1_k127_335321_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000594 233.0
HKD1_k127_335321_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004352 234.0
HKD1_k127_335321_9 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000005513 229.0
HKD1_k127_3370823_0 Periplasmic glucan biosynthesis protein, MdoG K03670 - - 2.884e-210 666.0
HKD1_k127_3370823_1 Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 603.0
HKD1_k127_3370823_10 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000005706 192.0
HKD1_k127_3370823_11 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000004193 193.0
HKD1_k127_3370823_12 PFAM Sulfate transporter antisigma-factor antagonist STAS K17762 - - 0.0000000000000000000000000000000000000006678 151.0
HKD1_k127_3370823_13 Stage II sporulation protein - - - 0.00000000000000000000000000000000003678 147.0
HKD1_k127_3370823_14 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.0000000000000000000000000000000006392 144.0
HKD1_k127_3370823_15 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000004595 121.0
HKD1_k127_3370823_16 Zn-dependent - - - 0.000000000000000000000000001083 124.0
HKD1_k127_3370823_17 GGDEF domain - - - 0.0000000000000000000000007543 115.0
HKD1_k127_3370823_18 ATP-grasp - - - 0.000000008568 62.0
HKD1_k127_3370823_2 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 540.0
HKD1_k127_3370823_3 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 472.0
HKD1_k127_3370823_4 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 418.0
HKD1_k127_3370823_5 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 356.0
HKD1_k127_3370823_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004587 246.0
HKD1_k127_3370823_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000003099 236.0
HKD1_k127_3370823_8 Glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000002636 224.0
HKD1_k127_3370823_9 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000002191 201.0
HKD1_k127_337440_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - 4.138e-244 766.0
HKD1_k127_337440_1 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 594.0
HKD1_k127_337440_2 FAD linked oxidase domain protein K05797 - 1.17.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 544.0
HKD1_k127_337440_3 - - - - 0.00000000000000000008763 90.0
HKD1_k127_337440_4 - - - - 0.000000000000000002692 100.0
HKD1_k127_337440_5 - - - - 0.000000009144 69.0
HKD1_k127_3413229_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1269.0
HKD1_k127_3413229_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1065.0
HKD1_k127_3413229_10 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 533.0
HKD1_k127_3413229_11 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 552.0
HKD1_k127_3413229_12 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 506.0
HKD1_k127_3413229_13 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 435.0
HKD1_k127_3413229_14 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 436.0
HKD1_k127_3413229_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 440.0
HKD1_k127_3413229_16 SMART transcription factor jumonji jmjC K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 422.0
HKD1_k127_3413229_17 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 415.0
HKD1_k127_3413229_18 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 396.0
HKD1_k127_3413229_19 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 403.0
HKD1_k127_3413229_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.294e-295 919.0
HKD1_k127_3413229_20 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 352.0
HKD1_k127_3413229_21 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 321.0
HKD1_k127_3413229_22 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 321.0
HKD1_k127_3413229_23 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 322.0
HKD1_k127_3413229_24 signal transduction histidine kinase K07644,K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 306.0
HKD1_k127_3413229_25 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 302.0
HKD1_k127_3413229_26 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 295.0
HKD1_k127_3413229_27 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
HKD1_k127_3413229_28 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 312.0
HKD1_k127_3413229_29 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007127 284.0
HKD1_k127_3413229_3 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 1.159e-236 750.0
HKD1_k127_3413229_30 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 277.0
HKD1_k127_3413229_31 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000144 253.0
HKD1_k127_3413229_32 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000006453 239.0
HKD1_k127_3413229_33 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000167 233.0
HKD1_k127_3413229_34 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.000000000000000000000000000000000000000000000000000000000000000001736 230.0
HKD1_k127_3413229_35 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000003505 204.0
HKD1_k127_3413229_36 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
HKD1_k127_3413229_37 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000003038 203.0
HKD1_k127_3413229_38 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000006716 196.0
HKD1_k127_3413229_39 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000001516 168.0
HKD1_k127_3413229_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.592e-204 660.0
HKD1_k127_3413229_40 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000004706 163.0
HKD1_k127_3413229_41 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000001743 168.0
HKD1_k127_3413229_42 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000008087 171.0
HKD1_k127_3413229_43 Sporulation related domain - - - 0.000000000000000000000000000000000001564 145.0
HKD1_k127_3413229_44 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000001326 145.0
HKD1_k127_3413229_45 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000001341 122.0
HKD1_k127_3413229_46 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000001329 117.0
HKD1_k127_3413229_47 - - - - 0.0000000000000000000205 102.0
HKD1_k127_3413229_48 Protein of unknown function (DUF3106) - - - 0.0000000000000001283 89.0
HKD1_k127_3413229_49 HIT domain - - - 0.0000000000000002524 87.0
HKD1_k127_3413229_5 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 622.0
HKD1_k127_3413229_50 Outer membrane efflux protein K15725 - - 0.00000000000008811 86.0
HKD1_k127_3413229_52 YjbR - - - 0.0000000000006334 76.0
HKD1_k127_3413229_53 - - - - 0.0000000001091 74.0
HKD1_k127_3413229_54 Uncharacterised nucleotidyltransferase - - - 0.00002489 57.0
HKD1_k127_3413229_6 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 588.0
HKD1_k127_3413229_7 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 587.0
HKD1_k127_3413229_8 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 545.0
HKD1_k127_3413229_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 538.0
HKD1_k127_3415921_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.801e-320 989.0
HKD1_k127_3415921_1 Peptidase S46 - - - 1.508e-298 932.0
HKD1_k127_3415921_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000007733 151.0
HKD1_k127_3415921_11 Short C-terminal domain K08982 - - 0.0000000000000001943 79.0
HKD1_k127_3415921_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 605.0
HKD1_k127_3415921_3 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 377.0
HKD1_k127_3415921_4 PFAM AsmA family protein K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 332.0
HKD1_k127_3415921_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 306.0
HKD1_k127_3415921_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 300.0
HKD1_k127_3415921_7 DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003037 239.0
HKD1_k127_3415921_8 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000009749 211.0
HKD1_k127_3415921_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000002576 180.0
HKD1_k127_343979_0 Molecular chaperone. Has ATPase activity K04079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 2.106e-236 746.0
HKD1_k127_343979_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 593.0
HKD1_k127_343979_10 integral membrane protein K02221 - - 0.0000000000000000000000000000000002682 138.0
HKD1_k127_343979_11 Domain of unknown function (DUF4426) - - - 0.0000000000000000000000000003706 121.0
HKD1_k127_343979_12 - - - - 0.000000000000000000000000000501 124.0
HKD1_k127_343979_13 protein conserved in bacteria - - - 0.0000000000000000000006078 100.0
HKD1_k127_343979_14 SnoaL-like polyketide cyclase K06893 - - 0.0000003846 60.0
HKD1_k127_343979_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 384.0
HKD1_k127_343979_3 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002951 254.0
HKD1_k127_343979_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000004494 221.0
HKD1_k127_343979_5 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000002017 216.0
HKD1_k127_343979_6 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000001122 215.0
HKD1_k127_343979_7 Serine aminopeptidase, S33 K07018 - - 0.0000000000000000000000000000000000000000000000005455 182.0
HKD1_k127_343979_8 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000001403 170.0
HKD1_k127_343979_9 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000004154 141.0
HKD1_k127_3444575_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.222e-224 707.0
HKD1_k127_3444575_1 TonB-dependent receptor K02014 - - 1.063e-223 717.0
HKD1_k127_3444575_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 310.0
HKD1_k127_3444575_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003142 247.0
HKD1_k127_3444575_4 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000116 152.0
HKD1_k127_3444575_5 - - - - 0.0000000000000000000000008075 106.0
HKD1_k127_3444575_6 SNARE associated Golgi protein - - - 0.00000000000000000000003064 115.0
HKD1_k127_3444575_7 - - - - 0.000000000000000000001102 111.0
HKD1_k127_3444575_8 - - - - 0.000000000000000000113 91.0
HKD1_k127_3517330_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.9,1.17.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 501.0
HKD1_k127_3517330_1 L-lactate dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 435.0
HKD1_k127_3517330_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002163 262.0
HKD1_k127_3517330_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000002423 195.0
HKD1_k127_3517330_4 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.00000001195 59.0
HKD1_k127_3655678_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 358.0
HKD1_k127_3655678_1 Transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 343.0
HKD1_k127_3655678_2 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
HKD1_k127_3655678_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 314.0
HKD1_k127_3655678_4 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 299.0
HKD1_k127_3655678_5 peroxidase activity K00435 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004063 259.0
HKD1_k127_3655678_6 Belongs to the precorrin methyltransferase family K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000006769 165.0
HKD1_k127_3655678_7 phosphorelay signal transduction system - - - 0.00000005049 54.0
HKD1_k127_3737468_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1449.0
HKD1_k127_3737468_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 2.948e-223 702.0
HKD1_k127_3737468_10 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 345.0
HKD1_k127_3737468_11 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 334.0
HKD1_k127_3737468_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 329.0
HKD1_k127_3737468_13 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 328.0
HKD1_k127_3737468_14 Cbb3-type cytochrome oxidase cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000706 254.0
HKD1_k127_3737468_15 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000005445 248.0
HKD1_k127_3737468_16 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000002384 237.0
HKD1_k127_3737468_17 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000004809 244.0
HKD1_k127_3737468_18 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000001251 200.0
HKD1_k127_3737468_19 nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000001516 192.0
HKD1_k127_3737468_2 Belongs to the heme-copper respiratory oxidase family K00404 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 609.0
HKD1_k127_3737468_20 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000008491 171.0
HKD1_k127_3737468_21 Auxin binding protein - - - 0.00000000000000000000000000000001903 131.0
HKD1_k127_3737468_22 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000001736 119.0
HKD1_k127_3737468_23 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000004875 126.0
HKD1_k127_3737468_24 MobA-Related Protein K00087,K07141,K07402,K19190 - 1.1.1.328,1.17.1.4,2.7.7.76 0.00000000000000000000000008728 117.0
HKD1_k127_3737468_25 Yip1 domain - - - 0.00000000000000000009534 102.0
HKD1_k127_3737468_26 YKOF-related Family - - - 0.0000000000003939 72.0
HKD1_k127_3737468_27 Choline kinase - - - 0.000000000000876 81.0
HKD1_k127_3737468_3 TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 554.0
HKD1_k127_3737468_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 428.0
HKD1_k127_3737468_5 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 444.0
HKD1_k127_3737468_6 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 413.0
HKD1_k127_3737468_7 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 413.0
HKD1_k127_3737468_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 404.0
HKD1_k127_3737468_9 Major facilitator K05819,K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 398.0
HKD1_k127_383540_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1569.0
HKD1_k127_383540_1 Heat shock 70 kDa protein K04043 - - 6.03e-322 995.0
HKD1_k127_383540_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 550.0
HKD1_k127_383540_11 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 520.0
HKD1_k127_383540_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 512.0
HKD1_k127_383540_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 474.0
HKD1_k127_383540_14 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 450.0
HKD1_k127_383540_15 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 389.0
HKD1_k127_383540_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 304.0
HKD1_k127_383540_17 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
HKD1_k127_383540_18 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006861 272.0
HKD1_k127_383540_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001222 270.0
HKD1_k127_383540_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.415e-304 944.0
HKD1_k127_383540_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
HKD1_k127_383540_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001126 261.0
HKD1_k127_383540_22 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000007199 236.0
HKD1_k127_383540_23 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003143 233.0
HKD1_k127_383540_24 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000007873 216.0
HKD1_k127_383540_25 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000002514 219.0
HKD1_k127_383540_26 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000003045 215.0
HKD1_k127_383540_27 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000161 209.0
HKD1_k127_383540_28 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000003855 201.0
HKD1_k127_383540_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000005649 174.0
HKD1_k127_383540_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 3.488e-277 868.0
HKD1_k127_383540_30 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000001264 170.0
HKD1_k127_383540_31 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000001426 144.0
HKD1_k127_383540_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000001925 148.0
HKD1_k127_383540_33 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000009284 139.0
HKD1_k127_383540_34 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000419 104.0
HKD1_k127_383540_35 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000007088 89.0
HKD1_k127_383540_36 - - - - 0.000000000003508 73.0
HKD1_k127_383540_37 - - - - 0.000000003026 61.0
HKD1_k127_383540_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.001e-247 766.0
HKD1_k127_383540_41 - - - - 0.0005676 52.0
HKD1_k127_383540_5 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 2.193e-233 758.0
HKD1_k127_383540_6 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.492e-223 703.0
HKD1_k127_383540_7 Spermine/spermidine synthase domain - - - 2.003e-201 659.0
HKD1_k127_383540_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.663e-199 628.0
HKD1_k127_383540_9 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 548.0
HKD1_k127_38767_0 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 447.0
HKD1_k127_38767_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 409.0
HKD1_k127_38767_2 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 366.0
HKD1_k127_38767_3 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000002838 206.0
HKD1_k127_388907_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1356.0
HKD1_k127_388907_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788 - - 0.0 1160.0
HKD1_k127_388907_10 Asp Glu hydantoin racemase K01799,K06033 - 4.1.1.76,5.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002479 244.0
HKD1_k127_388907_11 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000001078 188.0
HKD1_k127_388907_12 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000003481 194.0
HKD1_k127_388907_13 - - - - 0.000000000000000000000000000000000000000000000007179 192.0
HKD1_k127_388907_14 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000001035 181.0
HKD1_k127_388907_15 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000006504 147.0
HKD1_k127_388907_16 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000000000000005129 132.0
HKD1_k127_388907_17 PepSY-associated TM region - - - 0.00000000000000000000000000005716 130.0
HKD1_k127_388907_18 Protein of unknown function (DUF3592) - - - 0.00000000000000000000000002783 128.0
HKD1_k127_388907_19 COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit - - - 0.00000000000000127 80.0
HKD1_k127_388907_2 Elongator protein 3, MiaB family, Radical SAM - - - 8.476e-248 782.0
HKD1_k127_388907_20 OmpA-like transmembrane domain K03286 - - 0.000005329 52.0
HKD1_k127_388907_21 Protein of unknown function (DUF1109) - - - 0.000024 55.0
HKD1_k127_388907_3 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 545.0
HKD1_k127_388907_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 491.0
HKD1_k127_388907_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 466.0
HKD1_k127_388907_6 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 430.0
HKD1_k127_388907_7 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 349.0
HKD1_k127_388907_8 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 343.0
HKD1_k127_388907_9 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000004944 267.0
HKD1_k127_389794_0 UPF0313 protein - - - 0.0 1075.0
HKD1_k127_389794_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 4.664e-209 666.0
HKD1_k127_389794_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 409.0
HKD1_k127_389794_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000308 169.0
HKD1_k127_389794_4 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000001974 147.0
HKD1_k127_389794_5 Protein conserved in bacteria - - - 0.00000000000000000000000004044 122.0
HKD1_k127_389794_6 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000369 103.0
HKD1_k127_389794_7 PA14 - - - 0.0000000008643 72.0
HKD1_k127_389794_8 NfeD-like C-terminal, partner-binding - - - 0.00000009931 59.0
HKD1_k127_3916304_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 4.495e-194 617.0
HKD1_k127_3916304_1 General secretion pathway protein K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 414.0
HKD1_k127_3916304_2 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 314.0
HKD1_k127_4028040_0 ATPase FliI YscN family K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 551.0
HKD1_k127_4028040_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 437.0
HKD1_k127_4028040_10 Flagellar assembly protein K02411 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000006959 88.0
HKD1_k127_4028040_11 FlaG protein K06603 - - 0.0000001378 59.0
HKD1_k127_4028040_12 bacterial-type flagellum organization K02413 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001717 58.0
HKD1_k127_4028040_13 - - - - 0.0000002518 54.0
HKD1_k127_4028040_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 442.0
HKD1_k127_4028040_3 sigma54 specific, transcriptional regulator, Fis family K10941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 362.0
HKD1_k127_4028040_4 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 342.0
HKD1_k127_4028040_5 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 300.0
HKD1_k127_4028040_6 Histidine kinase K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000002679 257.0
HKD1_k127_4028040_7 flagellar protein FliS K02422 - - 0.000000000000000000000000000001427 124.0
HKD1_k127_4028040_8 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000003961 118.0
HKD1_k127_4028040_9 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000009681 92.0
HKD1_k127_4104598_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 2.366e-303 946.0
HKD1_k127_4104598_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 546.0
HKD1_k127_4104598_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000001913 250.0
HKD1_k127_4104598_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000005203 252.0
HKD1_k127_4104598_12 FimV C-terminal K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000004381 251.0
HKD1_k127_4104598_13 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000001298 154.0
HKD1_k127_4104598_14 SnoaL-like domain - - - 0.0000000000000000000000000221 118.0
HKD1_k127_4104598_15 - - - - 0.00000000000000000009648 94.0
HKD1_k127_4104598_16 - - - - 0.0000000000000001052 92.0
HKD1_k127_4104598_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 395.0
HKD1_k127_4104598_3 Ankyrin repeats (3 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 376.0
HKD1_k127_4104598_4 lysine 2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 344.0
HKD1_k127_4104598_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 324.0
HKD1_k127_4104598_6 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 305.0
HKD1_k127_4104598_7 PFAM EAL domain K21025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 321.0
HKD1_k127_4104598_8 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000313 279.0
HKD1_k127_4104598_9 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000006959 265.0
HKD1_k127_4117166_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.366e-299 949.0
HKD1_k127_4117166_1 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10011 - 1.1.1.305,2.1.2.13 2e-293 919.0
HKD1_k127_4117166_10 Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10012 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0044464,GO:0071944,GO:0099621 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 383.0
HKD1_k127_4117166_11 response regulator K07776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 319.0
HKD1_k127_4117166_12 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 330.0
HKD1_k127_4117166_13 Putative ABC exporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 342.0
HKD1_k127_4117166_14 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 324.0
HKD1_k127_4117166_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008434 279.0
HKD1_k127_4117166_16 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004556 286.0
HKD1_k127_4117166_17 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001052 269.0
HKD1_k127_4117166_18 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000004647 260.0
HKD1_k127_4117166_19 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001292 246.0
HKD1_k127_4117166_2 TonB dependent receptor - - - 2.802e-207 684.0
HKD1_k127_4117166_20 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000001624 230.0
HKD1_k127_4117166_21 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000003227 211.0
HKD1_k127_4117166_22 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.00000000000000000000000000000000000000000000000000000001169 211.0
HKD1_k127_4117166_23 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000003944 209.0
HKD1_k127_4117166_24 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000004284 203.0
HKD1_k127_4117166_25 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000006476 179.0
HKD1_k127_4117166_26 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000155 179.0
HKD1_k127_4117166_27 S1/P1 Nuclease - - - 0.000000000000000000000000000000000000000006207 172.0
HKD1_k127_4117166_28 S1 P1 nuclease - - - 0.000000000000000000000000000000003433 144.0
HKD1_k127_4117166_29 PFAM PspA IM30 - - - 0.000000000000000000000000000000009527 134.0
HKD1_k127_4117166_3 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 533.0
HKD1_k127_4117166_30 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.00000000000000000000000000000003429 146.0
HKD1_k127_4117166_31 Signal transduction protein - - - 0.00000000000000000000000000000006505 131.0
HKD1_k127_4117166_32 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000005388 140.0
HKD1_k127_4117166_33 Diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000002565 122.0
HKD1_k127_4117166_34 - - - - 0.00000000000000000000000003815 117.0
HKD1_k127_4117166_35 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000006224 116.0
HKD1_k127_4117166_36 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000002111 105.0
HKD1_k127_4117166_37 Permeases of the drug metabolite transporter (DMT) superfamily K12962 - - 0.00000000000000001526 93.0
HKD1_k127_4117166_38 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000001019 86.0
HKD1_k127_4117166_39 COG0457 FOG TPR repeat - - - 0.0000000009299 71.0
HKD1_k127_4117166_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 522.0
HKD1_k127_4117166_40 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000007792 68.0
HKD1_k127_4117166_41 Small Multidrug Resistance protein - - - 0.0000004173 61.0
HKD1_k127_4117166_42 DnaJ molecular chaperone homology domain K05516 - - 0.00005417 53.0
HKD1_k127_4117166_5 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 490.0
HKD1_k127_4117166_6 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 430.0
HKD1_k127_4117166_7 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 427.0
HKD1_k127_4117166_8 von Willebrand factor, type A K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 413.0
HKD1_k127_4117166_9 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 388.0
HKD1_k127_4122651_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 7.512e-293 905.0
HKD1_k127_4122651_1 COG4993 Glucose dehydrogenase - - - 4.459e-216 695.0
HKD1_k127_4122651_10 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 299.0
HKD1_k127_4122651_11 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 312.0
HKD1_k127_4122651_12 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006838 306.0
HKD1_k127_4122651_13 N-acetyltransferase K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001254 285.0
HKD1_k127_4122651_14 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 265.0
HKD1_k127_4122651_15 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000003019 234.0
HKD1_k127_4122651_16 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000001321 238.0
HKD1_k127_4122651_17 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000007029 197.0
HKD1_k127_4122651_18 - - - - 0.00000000000000000000000000000000000000000000000005786 193.0
HKD1_k127_4122651_19 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000008764 182.0
HKD1_k127_4122651_2 Dehydrogenase K00114 - 1.1.2.8 3.944e-203 648.0
HKD1_k127_4122651_20 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000001159 197.0
HKD1_k127_4122651_21 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000009974 170.0
HKD1_k127_4122651_22 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000001462 153.0
HKD1_k127_4122651_23 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.000000000000000000000000000000000000186 153.0
HKD1_k127_4122651_24 YceI-like domain - - - 0.000000000000000000000002434 113.0
HKD1_k127_4122651_25 - - - - 0.0000000000000000000001109 109.0
HKD1_k127_4122651_27 - - - - 0.00000000004825 72.0
HKD1_k127_4122651_28 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.00000001063 63.0
HKD1_k127_4122651_29 - - - - 0.00000001612 68.0
HKD1_k127_4122651_3 PQQ-like domain K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 584.0
HKD1_k127_4122651_30 - - - - 0.00000002777 67.0
HKD1_k127_4122651_31 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000008995 64.0
HKD1_k127_4122651_32 STAS domain K07122 - - 0.000002877 59.0
HKD1_k127_4122651_33 COG4235 Cytochrome c biogenesis factor K02200 - - 0.00006577 52.0
HKD1_k127_4122651_4 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 559.0
HKD1_k127_4122651_5 metal-dependent hydrolase of the TIM-barrel fold K03392,K10220 - 4.1.1.45,4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 527.0
HKD1_k127_4122651_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 525.0
HKD1_k127_4122651_7 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 486.0
HKD1_k127_4122651_8 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 331.0
HKD1_k127_4122651_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 322.0
HKD1_k127_4128415_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001037 284.0
HKD1_k127_4128415_1 PFAM LppC K07121 - - 0.000000000000000000000000000000000000000000000000000000001708 222.0
HKD1_k127_4128415_2 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000001512 148.0
HKD1_k127_4128415_3 - - - - 0.00000000000000000000000003026 113.0
HKD1_k127_4128620_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1300.0
HKD1_k127_4128620_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.391e-255 805.0
HKD1_k127_4128620_10 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 370.0
HKD1_k127_4128620_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 364.0
HKD1_k127_4128620_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 356.0
HKD1_k127_4128620_13 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 344.0
HKD1_k127_4128620_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 351.0
HKD1_k127_4128620_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 331.0
HKD1_k127_4128620_16 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 307.0
HKD1_k127_4128620_17 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 302.0
HKD1_k127_4128620_18 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006748 282.0
HKD1_k127_4128620_19 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004723 281.0
HKD1_k127_4128620_2 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 5.374e-224 709.0
HKD1_k127_4128620_20 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000005415 231.0
HKD1_k127_4128620_21 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000006576 222.0
HKD1_k127_4128620_22 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000002964 210.0
HKD1_k127_4128620_23 - - - - 0.0000000000000000000000000000000000000000000000000000000005157 205.0
HKD1_k127_4128620_24 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000007147 203.0
HKD1_k127_4128620_25 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000001095 193.0
HKD1_k127_4128620_26 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000002503 197.0
HKD1_k127_4128620_27 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000002914 194.0
HKD1_k127_4128620_28 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000000419 171.0
HKD1_k127_4128620_29 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000002145 163.0
HKD1_k127_4128620_3 Protein tyrosine kinase - - - 2.349e-212 687.0
HKD1_k127_4128620_30 Methyltransferase domain - - - 0.0000000000000000000000000000000000000008199 162.0
HKD1_k127_4128620_31 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000002466 150.0
HKD1_k127_4128620_32 - - - - 0.0000000000000000000000000000005868 126.0
HKD1_k127_4128620_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000003365 65.0
HKD1_k127_4128620_35 Beta-lactamase - - - 0.00000004323 62.0
HKD1_k127_4128620_36 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0004645 53.0
HKD1_k127_4128620_4 Diguanylate cyclase - - - 3.007e-195 640.0
HKD1_k127_4128620_5 PFAM Type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 515.0
HKD1_k127_4128620_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 499.0
HKD1_k127_4128620_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 431.0
HKD1_k127_4128620_8 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 425.0
HKD1_k127_4128620_9 L-2-hydroxyglutarate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 402.0
HKD1_k127_4136769_0 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 2.465e-275 864.0
HKD1_k127_4136769_1 Binding-protein-dependent transport systems inner membrane component K02050 - - 1.762e-223 707.0
HKD1_k127_4136769_10 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000002016 236.0
HKD1_k127_4136769_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000006273 233.0
HKD1_k127_4136769_12 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000009264 202.0
HKD1_k127_4136769_13 Domain of unknown function (DUF4399) - - - 0.0000000000000000000000000000000000000000001424 166.0
HKD1_k127_4136769_14 NlpC/P60 family - - - 0.000000000000000000000000007767 118.0
HKD1_k127_4136769_15 - - - - 0.00000000000000000000000005286 123.0
HKD1_k127_4136769_16 OmpA family - - - 0.000000000000000001269 96.0
HKD1_k127_4136769_17 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000008576 95.0
HKD1_k127_4136769_18 - - - - 0.0001219 55.0
HKD1_k127_4136769_19 COG1716 FOG FHA domain - - - 0.0001232 54.0
HKD1_k127_4136769_2 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 623.0
HKD1_k127_4136769_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 496.0
HKD1_k127_4136769_4 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 516.0
HKD1_k127_4136769_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 448.0
HKD1_k127_4136769_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 334.0
HKD1_k127_4136769_7 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 302.0
HKD1_k127_4136769_8 Secreted protein, containing von Willebrand factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003 296.0
HKD1_k127_4136769_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004157 267.0
HKD1_k127_4150390_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.068e-248 780.0
HKD1_k127_4150390_1 TonB dependent receptor K02014 - - 1.235e-197 647.0
HKD1_k127_4150390_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000008477 134.0
HKD1_k127_4150390_11 DoxX-like family - - - 0.000000000000000000000000000002037 121.0
HKD1_k127_4150390_12 - - - - 0.00000000000000000000000001353 113.0
HKD1_k127_4150390_13 PFAM amidohydrolase - - - 0.000000000000000000003198 107.0
HKD1_k127_4150390_14 endoribonuclease L-PSP - - - 0.00000000000000000001885 97.0
HKD1_k127_4150390_15 Domain of unknown function (DUF4404) - - - 0.0000001565 58.0
HKD1_k127_4150390_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 536.0
HKD1_k127_4150390_4 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004105 267.0
HKD1_k127_4150390_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000000001835 209.0
HKD1_k127_4150390_7 Protein of unknown function (DUF1097) - - - 0.00000000000000000000000000000000000000000000002102 178.0
HKD1_k127_4150390_8 - - - - 0.0000000000000000000000000000000000000000000478 166.0
HKD1_k127_4150390_9 - - - - 0.0000000000000000000000000000004147 128.0
HKD1_k127_4155956_0 response regulator receiver K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 590.0
HKD1_k127_4155956_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 567.0
HKD1_k127_4155956_2 acetoacetate metabolism regulatory protein AtoC K07714 K07715 GO:0000156,GO:0000160,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001130,GO:0001150,GO:0001151,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0035556,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 500.0
HKD1_k127_4155956_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 452.0
HKD1_k127_4155956_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 355.0
HKD1_k127_4155956_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 318.0
HKD1_k127_4155956_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000009174 170.0
HKD1_k127_4155956_7 HDOD domain - - - 0.000000000000000000000000000000000000000005639 167.0
HKD1_k127_4155956_8 Hep Hag repeat protein - - - 0.0000000000002715 77.0
HKD1_k127_4208178_0 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 438.0
HKD1_k127_4208178_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 430.0
HKD1_k127_4208178_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 384.0
HKD1_k127_4208178_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 377.0
HKD1_k127_4208178_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 291.0
HKD1_k127_4208178_5 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000135 181.0
HKD1_k127_4208178_6 - - - - 0.0000006885 59.0
HKD1_k127_4212495_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.909e-318 987.0
HKD1_k127_4212495_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.359e-208 655.0
HKD1_k127_4212495_10 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 302.0
HKD1_k127_4212495_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000002359 250.0
HKD1_k127_4212495_12 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000001853 243.0
HKD1_k127_4212495_13 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000002278 248.0
HKD1_k127_4212495_14 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000001972 218.0
HKD1_k127_4212495_15 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000001535 179.0
HKD1_k127_4212495_16 VIT family - - - 0.000000000000000000000000000000000000000000007382 174.0
HKD1_k127_4212495_17 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.45 0.0000000000000000000000000000000000003124 141.0
HKD1_k127_4212495_18 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000001394 143.0
HKD1_k127_4212495_19 Rhodanese Homology Domain - - - 0.000000000000000000000000002035 115.0
HKD1_k127_4212495_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 608.0
HKD1_k127_4212495_20 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000007367 104.0
HKD1_k127_4212495_22 - - - - 0.000000000301 69.0
HKD1_k127_4212495_23 cytochrome - - - 0.0000000009505 67.0
HKD1_k127_4212495_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 550.0
HKD1_k127_4212495_4 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 524.0
HKD1_k127_4212495_5 Sugar (and other) transporter K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 442.0
HKD1_k127_4212495_6 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 415.0
HKD1_k127_4212495_7 Helix-turn-helix domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 361.0
HKD1_k127_4212495_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 362.0
HKD1_k127_4212495_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 334.0
HKD1_k127_4229988_0 Glucoamylase and related glycosyl hydrolases - - - 6.057e-209 676.0
HKD1_k127_4229988_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 556.0
HKD1_k127_4229988_2 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697,K03692 - 2.4.1.15,2.4.1.213,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 436.0
HKD1_k127_4229988_3 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000001635 239.0
HKD1_k127_4229988_4 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000002221 181.0
HKD1_k127_4229988_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000005258 184.0
HKD1_k127_4229988_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000034 114.0
HKD1_k127_4253407_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.263e-220 691.0
HKD1_k127_4253407_1 PFAM ABC transporter related K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 412.0
HKD1_k127_4253407_10 - - - - 0.00003455 55.0
HKD1_k127_4253407_2 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 380.0
HKD1_k127_4253407_3 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007437 283.0
HKD1_k127_4253407_4 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000005101 241.0
HKD1_k127_4253407_5 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000003505 117.0
HKD1_k127_4253407_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000006332 112.0
HKD1_k127_4253407_7 Protein involved in outer membrane biogenesis - - - 0.000000000000000000002656 102.0
HKD1_k127_4253407_8 - - - - 0.00000000000001127 87.0
HKD1_k127_4264348_0 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 475.0
HKD1_k127_4264348_1 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 385.0
HKD1_k127_4264348_10 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000009105 126.0
HKD1_k127_4264348_11 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000007825 106.0
HKD1_k127_4264348_12 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000003638 92.0
HKD1_k127_4264348_13 sequence-specific DNA binding - - - 0.00000000000000003005 91.0
HKD1_k127_4264348_14 Fibronectin type III domain - - - 0.0000000000000008718 79.0
HKD1_k127_4264348_15 Small multidrug resistance protein K11741 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000001021 76.0
HKD1_k127_4264348_16 Universal stress protein family - - - 0.00000000000004371 83.0
HKD1_k127_4264348_17 - - - - 0.00000000002543 75.0
HKD1_k127_4264348_18 polyketide cyclase - - - 0.000000001686 65.0
HKD1_k127_4264348_19 methyltransferase - - - 0.000001426 51.0
HKD1_k127_4264348_2 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 331.0
HKD1_k127_4264348_20 domain protein - - - 0.00001396 59.0
HKD1_k127_4264348_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 326.0
HKD1_k127_4264348_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
HKD1_k127_4264348_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001096 214.0
HKD1_k127_4264348_6 PFAM SMP-30 Gluconolaconase K01179,K01181,K01218,K02014 - 3.2.1.4,3.2.1.78,3.2.1.8 0.0000000000000000000000000000000000000000009527 180.0
HKD1_k127_4264348_7 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000001321 155.0
HKD1_k127_4264348_8 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000186 148.0
HKD1_k127_4264348_9 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000682 148.0
HKD1_k127_4287802_0 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 295.0
HKD1_k127_4287802_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000217 295.0
HKD1_k127_4287802_2 ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006043 258.0
HKD1_k127_4287802_3 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002083 263.0
HKD1_k127_4287802_4 acetyltransferase - - - 0.0000000000000000000000000000000000000002965 169.0
HKD1_k127_4287802_5 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000008719 123.0
HKD1_k127_4287802_6 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000006414 87.0
HKD1_k127_4291956_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.266e-238 749.0
HKD1_k127_4291956_1 receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 606.0
HKD1_k127_4291956_2 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 421.0
HKD1_k127_4291956_3 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 402.0
HKD1_k127_4291956_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002457 272.0
HKD1_k127_4291956_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001095 274.0
HKD1_k127_4291956_6 - - - - 0.00000000000000000000000000000000000000001244 162.0
HKD1_k127_4294314_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 482.0
HKD1_k127_4294314_1 Catalyzes a key regulatory step in fatty acid biosynthesis K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 372.0
HKD1_k127_4294314_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002036 301.0
HKD1_k127_4294314_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000323 275.0
HKD1_k127_4294314_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000003311 231.0
HKD1_k127_4294314_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000615 152.0
HKD1_k127_4294314_6 - - - - 0.000000000505 61.0
HKD1_k127_4308705_0 TonB-dependent Receptor Plug K02014 - - 6.618e-316 988.0
HKD1_k127_4308705_1 Metallopeptidase family M24 - - - 3.074e-195 622.0
HKD1_k127_4308705_10 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001293 268.0
HKD1_k127_4308705_11 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000009476 204.0
HKD1_k127_4308705_12 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000001189 206.0
HKD1_k127_4308705_13 glyoxalase III activity K02005 - - 0.00000000000000000000000000000000000000000000000000001877 194.0
HKD1_k127_4308705_14 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000001629 183.0
HKD1_k127_4308705_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000004102 166.0
HKD1_k127_4308705_16 COG3764 Sortase (surface protein transpeptidase) K07284 - 3.4.22.70 0.000000000000000000000000000000000000003158 159.0
HKD1_k127_4308705_17 - - - - 0.0000000000000000000000000001099 122.0
HKD1_k127_4308705_19 metal cluster binding - - - 0.00000000003116 76.0
HKD1_k127_4308705_2 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 577.0
HKD1_k127_4308705_20 Domain of unknown function (DUF1905) - - - 0.00000000005406 69.0
HKD1_k127_4308705_21 Serine aminopeptidase, S33 - - - 0.00000002298 62.0
HKD1_k127_4308705_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 500.0
HKD1_k127_4308705_4 Dimerisation domain K09846 - 2.1.1.210 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 412.0
HKD1_k127_4308705_5 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 415.0
HKD1_k127_4308705_6 Aspartyl asparaginyl beta-hydroxylase and related dioxygenases K12979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 354.0
HKD1_k127_4308705_7 COG0501 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 328.0
HKD1_k127_4308705_8 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002645 271.0
HKD1_k127_4308705_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 266.0
HKD1_k127_4360059_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1566.0
HKD1_k127_4360059_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.366e-305 946.0
HKD1_k127_4360059_10 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 517.0
HKD1_k127_4360059_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 510.0
HKD1_k127_4360059_12 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 475.0
HKD1_k127_4360059_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 471.0
HKD1_k127_4360059_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 308.0
HKD1_k127_4360059_15 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
HKD1_k127_4360059_16 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002674 273.0
HKD1_k127_4360059_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 268.0
HKD1_k127_4360059_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002137 258.0
HKD1_k127_4360059_19 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000002807 237.0
HKD1_k127_4360059_2 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 2.07e-272 854.0
HKD1_k127_4360059_20 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
HKD1_k127_4360059_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000004173 214.0
HKD1_k127_4360059_22 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000002433 211.0
HKD1_k127_4360059_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000003001 174.0
HKD1_k127_4360059_24 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000001741 174.0
HKD1_k127_4360059_25 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000904 160.0
HKD1_k127_4360059_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000002616 147.0
HKD1_k127_4360059_27 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000004269 101.0
HKD1_k127_4360059_28 Bacterial transcription activator, effector binding domain - - - 0.000000000005078 72.0
HKD1_k127_4360059_29 - - - - 0.00000000001604 70.0
HKD1_k127_4360059_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.749e-244 757.0
HKD1_k127_4360059_30 - - - - 0.000003583 59.0
HKD1_k127_4360059_4 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 5.648e-230 744.0
HKD1_k127_4360059_5 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 4.765e-223 702.0
HKD1_k127_4360059_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.555e-201 634.0
HKD1_k127_4360059_7 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 633.0
HKD1_k127_4360059_8 carbamoyl-phosphate synthetase glutamine chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 546.0
HKD1_k127_4360059_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 546.0
HKD1_k127_4371167_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.194e-247 771.0
HKD1_k127_4371167_1 Radical SAM - - - 9.043e-201 648.0
HKD1_k127_4371167_10 Putative zinc-finger - - - 0.0000000000000000000000000000000000003057 157.0
HKD1_k127_4371167_11 Flagellar motor protein K02557 - - 0.00000000000000000000000000001565 129.0
HKD1_k127_4371167_12 MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000006523 122.0
HKD1_k127_4371167_13 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000014 106.0
HKD1_k127_4371167_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00001772 56.0
HKD1_k127_4371167_3 Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 401.0
HKD1_k127_4371167_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 370.0
HKD1_k127_4371167_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000173 220.0
HKD1_k127_4371167_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000001597 207.0
HKD1_k127_4371167_7 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000003018 200.0
HKD1_k127_4371167_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000539 164.0
HKD1_k127_4371167_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000009869 149.0
HKD1_k127_4399415_0 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 593.0
HKD1_k127_4399415_1 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 483.0
HKD1_k127_4399415_2 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000008674 247.0
HKD1_k127_4399415_3 COG0457 FOG TPR repeat - - - 0.00000000000000002532 96.0
HKD1_k127_4399415_4 - - - - 0.000000000001281 81.0
HKD1_k127_4399415_5 - - - - 0.0001433 55.0
HKD1_k127_44683_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 549.0
HKD1_k127_44683_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 505.0
HKD1_k127_44683_10 - - - - 0.0000003119 59.0
HKD1_k127_44683_11 FR47-like protein K06976 - - 0.000006591 58.0
HKD1_k127_44683_2 Major facilitator Superfamily K03762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 382.0
HKD1_k127_44683_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 333.0
HKD1_k127_44683_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 309.0
HKD1_k127_44683_5 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 311.0
HKD1_k127_44683_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000061 207.0
HKD1_k127_44683_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000003956 173.0
HKD1_k127_44683_8 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000005945 151.0
HKD1_k127_44683_9 Domain of unknown function (DUF4154) - - - 0.00000000000000000000001451 108.0
HKD1_k127_4491307_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1025.0
HKD1_k127_4491307_1 DNA topological change K03168 - 5.99.1.2 7.241e-198 644.0
HKD1_k127_4491307_10 serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000005544 254.0
HKD1_k127_4491307_11 Signal peptidase, peptidase S26 - - - 0.000000000000000000000000000000000000000000000000000000000000000008912 232.0
HKD1_k127_4491307_12 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000003237 244.0
HKD1_k127_4491307_13 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000002531 229.0
HKD1_k127_4491307_14 - - - - 0.00000000000000000000000000000000000000000000000000000000007161 214.0
HKD1_k127_4491307_15 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000003368 199.0
HKD1_k127_4491307_16 TraB family - - - 0.000000000000000000000000000000000000000000000000000004208 216.0
HKD1_k127_4491307_17 Redoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000008001 196.0
HKD1_k127_4491307_18 membrane protein domain - - - 0.000000000000000000000000000000000000000000000009874 180.0
HKD1_k127_4491307_19 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000001013 179.0
HKD1_k127_4491307_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 578.0
HKD1_k127_4491307_20 histone H4-K16 acetylation K07020 - - 0.0000000000000000000000000000000000000000000001886 175.0
HKD1_k127_4491307_21 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000004515 183.0
HKD1_k127_4491307_23 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000003537 160.0
HKD1_k127_4491307_24 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000005446 175.0
HKD1_k127_4491307_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001113 160.0
HKD1_k127_4491307_26 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000704 158.0
HKD1_k127_4491307_27 FtsX-like permease family K02004 - - 0.0000000000000000000000000000004136 130.0
HKD1_k127_4491307_28 Winged helix DNA-binding domain - - - 0.000000000000000000000000000003483 123.0
HKD1_k127_4491307_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 499.0
HKD1_k127_4491307_30 ankyrin repeat K21440 - - 0.0000000000000000000000001216 123.0
HKD1_k127_4491307_31 Protein conserved in bacteria K09796 - - 0.0000000000000000000004236 103.0
HKD1_k127_4491307_32 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000001126 102.0
HKD1_k127_4491307_34 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000004009 84.0
HKD1_k127_4491307_35 - - - - 0.00000000000001426 86.0
HKD1_k127_4491307_36 Polymer-forming cytoskeletal - - - 0.00000000000001776 87.0
HKD1_k127_4491307_37 NlpE C-terminal OB domain K06079 - - 0.00000006764 62.0
HKD1_k127_4491307_38 protein ubiquitination K09258,K15009,K20129 - - 0.000001548 61.0
HKD1_k127_4491307_4 Aldo/keto reductase family K00011 - 1.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 346.0
HKD1_k127_4491307_5 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 347.0
HKD1_k127_4491307_6 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 320.0
HKD1_k127_4491307_7 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
HKD1_k127_4491307_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006124 256.0
HKD1_k127_4491307_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000001759 243.0
HKD1_k127_4518663_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 3.529e-308 1006.0
HKD1_k127_4518663_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.055e-219 699.0
HKD1_k127_4518663_11 pyrophosphohydrolase K04765 - 3.6.1.9 0.000000237 53.0
HKD1_k127_4518663_12 Peptidase propeptide and YPEB domain - - - 0.00004878 52.0
HKD1_k127_4518663_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 603.0
HKD1_k127_4518663_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 321.0
HKD1_k127_4518663_4 signal transduction histidine kinase K07637 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 325.0
HKD1_k127_4518663_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000001098 227.0
HKD1_k127_4518663_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000003696 182.0
HKD1_k127_4518663_8 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000001006 99.0
HKD1_k127_4518663_9 outer membrane lipoprotein - - - 0.0000000000000000000001441 106.0
HKD1_k127_4661596_0 Glycogen debranching enzyme - - - 0.0 1432.0
HKD1_k127_4661596_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1050.0
HKD1_k127_4661596_10 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006841 284.0
HKD1_k127_4661596_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000008986 168.0
HKD1_k127_4661596_12 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000008703 156.0
HKD1_k127_4661596_13 Type II secretion system protein C - - - 0.00000000000000000000000000000000000000004585 166.0
HKD1_k127_4661596_14 Sugar efflux transporter for intercellular exchange - - - 0.00000000000000000000000000000000000000005841 155.0
HKD1_k127_4661596_15 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000002273 151.0
HKD1_k127_4661596_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000101 136.0
HKD1_k127_4661596_17 ABC transporter K02003 - - 0.0000000000000000000002113 98.0
HKD1_k127_4661596_18 PFAM VanZ - - - 0.0000000000001503 75.0
HKD1_k127_4661596_2 DNA segregation ATPase FtsK SpoIIIE K03466 - - 2.552e-272 857.0
HKD1_k127_4661596_3 A predicted alpha-helical domain with a conserved ER motif. - - - 2.451e-221 714.0
HKD1_k127_4661596_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 564.0
HKD1_k127_4661596_5 General Secretion Pathway protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 489.0
HKD1_k127_4661596_6 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 416.0
HKD1_k127_4661596_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 389.0
HKD1_k127_4661596_8 mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 346.0
HKD1_k127_4661596_9 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000157 310.0
HKD1_k127_4716926_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 614.0
HKD1_k127_4716926_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 550.0
HKD1_k127_4716926_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 344.0
HKD1_k127_4716926_3 Protein of unknown function (DUF4199) - - - 0.00000000000000000000000000000000000000001524 160.0
HKD1_k127_4716926_4 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000001783 151.0
HKD1_k127_4716926_5 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000006831 96.0
HKD1_k127_4716926_6 Protein of unknown function (DUF3426) - - - 0.000002284 57.0
HKD1_k127_477644_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.444e-285 890.0
HKD1_k127_477644_1 Flagellar hook protein FlgE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 485.0
HKD1_k127_477644_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005636 290.0
HKD1_k127_477644_11 Belongs to the flagella basal body rod proteins family K02391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008718 252.0
HKD1_k127_477644_12 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009323 244.0
HKD1_k127_477644_13 belongs to the bacterial solute-binding protein 3 family K02030,K02424,K10036 - - 0.00000000000000000000000000000000000000000000000000000000000000004123 235.0
HKD1_k127_477644_14 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
HKD1_k127_477644_15 COG3951 Rod binding protein K02395 GO:0003674,GO:0005198 - 0.0000000000000000000000000000000000000000000000000000000001024 216.0
HKD1_k127_477644_16 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000001104 209.0
HKD1_k127_477644_17 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000393 192.0
HKD1_k127_477644_18 domain protein - - - 0.0000000000000000000000000000000000000000000002419 181.0
HKD1_k127_477644_19 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000006017 174.0
HKD1_k127_477644_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 468.0
HKD1_k127_477644_20 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000000000005838 162.0
HKD1_k127_477644_21 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000002328 160.0
HKD1_k127_477644_22 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000006718 126.0
HKD1_k127_477644_23 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000326 111.0
HKD1_k127_477644_24 negative regulation of translational initiation - - - 0.0000000000000001153 89.0
HKD1_k127_477644_25 DsrE/DsrF-like family - - - 0.0000000000000006574 85.0
HKD1_k127_477644_26 PilZ domain - - - 0.0000000000001523 74.0
HKD1_k127_477644_27 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000002663 72.0
HKD1_k127_477644_28 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000001223 70.0
HKD1_k127_477644_29 FlgN protein - - - 0.000006589 54.0
HKD1_k127_477644_3 Belongs to the flagella basal body rod proteins family K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 440.0
HKD1_k127_477644_31 COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) K02398 - - 0.00008429 54.0
HKD1_k127_477644_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 420.0
HKD1_k127_477644_5 basal body rod K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 372.0
HKD1_k127_477644_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 361.0
HKD1_k127_477644_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 346.0
HKD1_k127_477644_8 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 316.0
HKD1_k127_477644_9 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 302.0
HKD1_k127_48038_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1155.0
HKD1_k127_48038_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 611.0
HKD1_k127_48038_2 PFAM response regulator receiver K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 539.0
HKD1_k127_48038_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 498.0
HKD1_k127_48038_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 439.0
HKD1_k127_48038_5 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 388.0
HKD1_k127_48038_6 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 361.0
HKD1_k127_48038_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001667 271.0
HKD1_k127_48038_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000002533 206.0
HKD1_k127_48038_9 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000000000002121 90.0
HKD1_k127_499077_0 Periplasmic glucan biosynthesis protein, MdoG K03670 - - 3.739e-212 674.0
HKD1_k127_499077_1 Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 603.0
HKD1_k127_499077_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000001038 235.0
HKD1_k127_499077_11 - - - - 0.00000000000000000000000000000000000000000000000000000000001123 221.0
HKD1_k127_499077_12 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000193 217.0
HKD1_k127_499077_13 - - - - 0.00000000000000000000000000000000000000000000000000000004031 214.0
HKD1_k127_499077_14 Glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000007299 202.0
HKD1_k127_499077_15 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000001009 213.0
HKD1_k127_499077_16 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000008005 197.0
HKD1_k127_499077_17 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000004877 192.0
HKD1_k127_499077_18 - - - - 0.00000000000000000000000000000000000000000000000009948 184.0
HKD1_k127_499077_19 - - - - 0.000000000000000000000000000000000000000000000004791 188.0
HKD1_k127_499077_2 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 580.0
HKD1_k127_499077_20 - - - - 0.00000000000000000000000000000000000000000008997 170.0
HKD1_k127_499077_21 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000008822 169.0
HKD1_k127_499077_22 PFAM Sulfate transporter antisigma-factor antagonist STAS K17762 - - 0.00000000000000000000000000000000000000146 152.0
HKD1_k127_499077_23 Stage II sporulation protein E K05518 - 3.1.3.3 0.00000000000000000000000000000000006988 146.0
HKD1_k127_499077_24 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000001503 137.0
HKD1_k127_499077_25 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.00000000000000000000000000008624 121.0
HKD1_k127_499077_26 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000001229 121.0
HKD1_k127_499077_27 (twin-arginine translocation) pathway signal - - - 0.0000000000000001612 87.0
HKD1_k127_499077_28 - - - - 0.000000000000003467 85.0
HKD1_k127_499077_29 - - - - 0.00000000000005093 75.0
HKD1_k127_499077_3 DNA topological change - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 544.0
HKD1_k127_499077_30 Cupin 2, conserved barrel domain protein - - - 0.0000000000001079 78.0
HKD1_k127_499077_4 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 415.0
HKD1_k127_499077_5 Thermolysin metallopeptidase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 411.0
HKD1_k127_499077_6 aspartyl asparaginyl beta-hydroxylase K12979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 355.0
HKD1_k127_499077_7 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 352.0
HKD1_k127_499077_8 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 350.0
HKD1_k127_499077_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000007213 240.0
HKD1_k127_5030596_0 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 465.0
HKD1_k127_5030596_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 410.0
HKD1_k127_5030596_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 304.0
HKD1_k127_5030596_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000006401 261.0
HKD1_k127_5030596_4 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000001513 194.0
HKD1_k127_5030596_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000216 181.0
HKD1_k127_5030596_6 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000006338 65.0
HKD1_k127_5048279_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 494.0
HKD1_k127_5048279_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 445.0
HKD1_k127_5048279_2 - - - - 0.000000000000000000000000000000000000006356 149.0
HKD1_k127_5048279_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000003549 49.0
HKD1_k127_5057612_0 Histidine kinase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 307.0
HKD1_k127_5057612_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005172 272.0
HKD1_k127_5057612_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000001447 228.0
HKD1_k127_5057612_3 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000641 196.0
HKD1_k127_5057612_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000004042 150.0
HKD1_k127_5057612_5 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000001668 135.0
HKD1_k127_5057612_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000005394 99.0
HKD1_k127_5057612_7 universal stress protein K14055 - - 0.0000000000005491 74.0
HKD1_k127_5066827_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 535.0
HKD1_k127_5066827_1 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 389.0
HKD1_k127_5066827_10 - - - - 0.00000000000000000000000000000000000000000000000000000814 201.0
HKD1_k127_5066827_11 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000419 184.0
HKD1_k127_5066827_12 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000001562 170.0
HKD1_k127_5066827_13 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000008243 144.0
HKD1_k127_5066827_14 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000219 143.0
HKD1_k127_5066827_15 - - - - 0.00000000000000000000000000000003969 134.0
HKD1_k127_5066827_16 Helix-turn-helix domain - - - 0.00000000000000000000000000000004752 130.0
HKD1_k127_5066827_17 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000004003 106.0
HKD1_k127_5066827_18 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000003664 100.0
HKD1_k127_5066827_19 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000007296 86.0
HKD1_k127_5066827_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 351.0
HKD1_k127_5066827_20 Planctomycete cytochrome C - - - 0.000000000000001269 89.0
HKD1_k127_5066827_21 Protein of unknown function (DUF1501) - - - 0.00000000000001089 73.0
HKD1_k127_5066827_3 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 346.0
HKD1_k127_5066827_4 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 346.0
HKD1_k127_5066827_5 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 287.0
HKD1_k127_5066827_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008992 254.0
HKD1_k127_5066827_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004533 250.0
HKD1_k127_5066827_8 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000000000000000001862 239.0
HKD1_k127_5066827_9 Pfam Cupin - - - 0.000000000000000000000000000000000000000000000000000000004465 201.0
HKD1_k127_5067483_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 4.597e-276 871.0
HKD1_k127_5067483_1 Multi-copper - - - 1.575e-242 782.0
HKD1_k127_5067483_10 - - - - 0.000001053 54.0
HKD1_k127_5067483_2 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 371.0
HKD1_k127_5067483_3 copper resistance K07233 - - 0.000000000000000000000000000000000000000000000000000000000000000000001481 248.0
HKD1_k127_5067483_4 helix_turn_helix, mercury resistance K19591 - - 0.0000000000000000000000000000000000000000004249 162.0
HKD1_k127_5067483_5 Thioesterase superfamily K19222 - 3.1.2.28 0.0000000000000000000000000000000000000126 147.0
HKD1_k127_5067483_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000002228 139.0
HKD1_k127_5067483_7 Protein of unknown function (DUF1090) - - - 0.00000000000000000000000001119 115.0
HKD1_k127_5067483_8 - - - - 0.0000000000000000000000009832 110.0
HKD1_k127_5067483_9 - - - - 0.0000009131 57.0
HKD1_k127_5077211_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 9.531e-260 812.0
HKD1_k127_5077211_1 ABC transporter C-terminal domain K15738 - - 2.74e-219 698.0
HKD1_k127_5077211_2 DNA topological change K03168 - 5.99.1.2 1.205e-206 668.0
HKD1_k127_5077211_3 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 9.517e-205 644.0
HKD1_k127_5077211_4 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 461.0
HKD1_k127_5077211_5 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 310.0
HKD1_k127_5077211_6 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002378 244.0
HKD1_k127_5077211_7 - - - - 0.000000000000000000004703 98.0
HKD1_k127_5077211_9 SnoaL-like domain - - - 0.000006697 56.0
HKD1_k127_5093063_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.049e-306 953.0
HKD1_k127_5093063_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 1.706e-267 849.0
HKD1_k127_5093063_10 RimK-like ATPgrasp N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 518.0
HKD1_k127_5093063_11 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 488.0
HKD1_k127_5093063_12 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 476.0
HKD1_k127_5093063_13 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 460.0
HKD1_k127_5093063_14 Surface antigen variable number K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 453.0
HKD1_k127_5093063_15 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 430.0
HKD1_k127_5093063_16 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04101,K05713 - 1.13.11.16,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 417.0
HKD1_k127_5093063_17 Glutamate-cysteine ligase family 2(GCS2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 421.0
HKD1_k127_5093063_18 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 413.0
HKD1_k127_5093063_19 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 388.0
HKD1_k127_5093063_2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01200,K01214 - 3.2.1.41,3.2.1.68 3.893e-244 771.0
HKD1_k127_5093063_20 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 403.0
HKD1_k127_5093063_21 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 376.0
HKD1_k127_5093063_22 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 340.0
HKD1_k127_5093063_23 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 337.0
HKD1_k127_5093063_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 335.0
HKD1_k127_5093063_25 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 328.0
HKD1_k127_5093063_26 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 301.0
HKD1_k127_5093063_27 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001211 274.0
HKD1_k127_5093063_28 Conserved Protein - - - 0.000000000000000000000000000000000000000000000000000000001263 206.0
HKD1_k127_5093063_29 SEC-C Motif Domain Protein - - - 0.0000000000000000000000000000000000000000000000000007457 192.0
HKD1_k127_5093063_3 PFAM Orn DAP Arg decarboxylase 2 K01585 - 4.1.1.19 5.416e-219 698.0
HKD1_k127_5093063_30 M56 family peptidase - - - 0.000000000000000000000000000000000000000000000007329 191.0
HKD1_k127_5093063_31 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.000000000000000000000000000000000000000000002749 167.0
HKD1_k127_5093063_33 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000002294 163.0
HKD1_k127_5093063_34 Penicillinase repressor - - - 0.0000000000000000000000000000000000003225 144.0
HKD1_k127_5093063_35 endonuclease activity - - - 0.0000000000000000000000000000000001089 144.0
HKD1_k127_5093063_36 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.0000000000000000000000000000001024 129.0
HKD1_k127_5093063_37 - - - - 0.0000000000000000000000000000004762 137.0
HKD1_k127_5093063_38 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.0000000000000000000000000002682 128.0
HKD1_k127_5093063_39 Uncharacterized ACR, COG1678 K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000004597 119.0
HKD1_k127_5093063_4 Belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 3.742e-218 691.0
HKD1_k127_5093063_40 COG3901 Regulator of nitric oxide reductase transcription K19339 - - 0.000000000000000000000000004773 127.0
HKD1_k127_5093063_41 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000001982 112.0
HKD1_k127_5093063_42 FMN_bind K19339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001852 86.0
HKD1_k127_5093063_43 Subtilase family - - - 0.0000002688 63.0
HKD1_k127_5093063_44 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000004895 55.0
HKD1_k127_5093063_45 - - - - 0.0002033 49.0
HKD1_k127_5093063_5 Peptidase dimerisation domain - - - 2.244e-197 625.0
HKD1_k127_5093063_6 Radical SAM superfamily K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 588.0
HKD1_k127_5093063_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 559.0
HKD1_k127_5093063_8 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 539.0
HKD1_k127_5093063_9 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 533.0
HKD1_k127_5093635_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1150.0
HKD1_k127_5093635_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 3.348e-234 737.0
HKD1_k127_5093635_10 Pilin (bacterial filament) K02650,K02655 - - 0.0000000000000000000000000000000000001608 145.0
HKD1_k127_5093635_11 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000009528 134.0
HKD1_k127_5093635_12 Pilin (bacterial filament) K02650 - - 0.0000000000000006957 84.0
HKD1_k127_5093635_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 516.0
HKD1_k127_5093635_3 Type II secretory pathway, component PulF K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 509.0
HKD1_k127_5093635_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 394.0
HKD1_k127_5093635_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02464,K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 326.0
HKD1_k127_5093635_6 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000223 282.0
HKD1_k127_5093635_7 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000004072 234.0
HKD1_k127_5093635_8 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000724 218.0
HKD1_k127_5093635_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000001348 186.0
HKD1_k127_5178684_0 GTP-binding protein TypA K06207 - - 1.567e-287 893.0
HKD1_k127_5178684_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003008 223.0
HKD1_k127_5178684_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000001277 211.0
HKD1_k127_5178684_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000004066 169.0
HKD1_k127_5178684_4 - - - - 0.00000000000000000000001377 111.0
HKD1_k127_5178684_5 - - - - 0.000000000003732 73.0
HKD1_k127_51857_0 Glucose / Sorbosone dehydrogenase - - - 5.733e-218 681.0
HKD1_k127_51857_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.918e-216 685.0
HKD1_k127_51857_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 491.0
HKD1_k127_51857_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000003785 169.0
HKD1_k127_51857_4 pfam nudix K08310 - 3.6.1.67 0.00000000000000000000000000000001904 143.0
HKD1_k127_5203973_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 7.638e-235 751.0
HKD1_k127_5203973_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058,K03778 - 1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 426.0
HKD1_k127_5203973_10 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000008083 149.0
HKD1_k127_5203973_11 - - - - 0.000000000000000000000005495 114.0
HKD1_k127_5203973_12 Peptidase family S51 - - - 0.0000000000000001726 91.0
HKD1_k127_5203973_13 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000001074 79.0
HKD1_k127_5203973_14 - - - - 0.000579 49.0
HKD1_k127_5203973_2 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 407.0
HKD1_k127_5203973_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 404.0
HKD1_k127_5203973_4 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 374.0
HKD1_k127_5203973_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008154 285.0
HKD1_k127_5203973_6 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002642 276.0
HKD1_k127_5203973_7 2Fe-2S -binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
HKD1_k127_5203973_8 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000005283 192.0
HKD1_k127_5203973_9 protein conserved in bacteria containing a divergent form of TPR repeats - - - 0.000000000000000000000000000000000000000000000002554 182.0
HKD1_k127_5204987_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 3.035e-197 624.0
HKD1_k127_5204987_1 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 521.0
HKD1_k127_5204987_10 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000005616 209.0
HKD1_k127_5204987_11 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000001786 198.0
HKD1_k127_5204987_12 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000912 147.0
HKD1_k127_5204987_13 protein conserved in bacteria K01814 - 5.3.1.16 0.0000000000000000000000000000000004188 146.0
HKD1_k127_5204987_14 enzyme of heme biosynthesis K02496 - 2.1.1.107 0.0000000000000000000000000002109 128.0
HKD1_k127_5204987_15 Membrane fusogenic activity K09806 - - 0.00000000000000002815 83.0
HKD1_k127_5204987_16 Domain of unknown function (DUF4124) - - - 0.000003301 55.0
HKD1_k127_5204987_17 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000258 54.0
HKD1_k127_5204987_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 336.0
HKD1_k127_5204987_3 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 316.0
HKD1_k127_5204987_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005049 285.0
HKD1_k127_5204987_5 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 286.0
HKD1_k127_5204987_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001931 256.0
HKD1_k127_5204987_7 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000006933 247.0
HKD1_k127_5204987_8 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000001799 234.0
HKD1_k127_5204987_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003559 236.0
HKD1_k127_5215761_0 Belongs to the peptidase M16 family K07263 - - 2.275e-299 948.0
HKD1_k127_5215761_1 E1-E2 ATPase K01535 - 3.6.3.6 6.081e-290 912.0
HKD1_k127_5215761_10 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 359.0
HKD1_k127_5215761_11 Enoyl-CoA hydratase/isomerase K18383 - 4.1.2.41,4.2.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 328.0
HKD1_k127_5215761_13 PRMT5 arginine-N-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000017 266.0
HKD1_k127_5215761_14 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001559 261.0
HKD1_k127_5215761_15 Serine threonine protein kinase - - - 0.0000000000000000000000000000000005378 151.0
HKD1_k127_5215761_16 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000006704 110.0
HKD1_k127_5215761_17 - - - - 0.000000000003529 72.0
HKD1_k127_5215761_18 - - - - 0.00002554 57.0
HKD1_k127_5215761_2 COG4993 Glucose dehydrogenase - - - 2.708e-230 733.0
HKD1_k127_5215761_3 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 1.101e-227 732.0
HKD1_k127_5215761_4 PQQ enzyme repeat - - - 1.873e-220 704.0
HKD1_k127_5215761_5 PQQ enzyme repeat - - - 5.363e-197 658.0
HKD1_k127_5215761_6 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 525.0
HKD1_k127_5215761_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 414.0
HKD1_k127_5215761_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 400.0
HKD1_k127_5215761_9 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 364.0
HKD1_k127_5233198_0 Outer membrane receptor K02014 - - 1.767e-214 690.0
HKD1_k127_5233198_1 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 517.0
HKD1_k127_5233198_2 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 439.0
HKD1_k127_5233198_3 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 437.0
HKD1_k127_5233198_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 371.0
HKD1_k127_5233198_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000691 219.0
HKD1_k127_5233198_6 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000001186 218.0
HKD1_k127_5233198_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000005123 232.0
HKD1_k127_5233198_8 Cytochrome c - - - 0.000000000000000000000000000001023 132.0
HKD1_k127_5233198_9 Peptidogalycan biosysnthesis/recognition - - - 0.00000000000000007931 93.0
HKD1_k127_5252564_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 402.0
HKD1_k127_5252564_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 314.0
HKD1_k127_5252564_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 295.0
HKD1_k127_5252564_3 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004233 295.0
HKD1_k127_5252564_4 PFAM RNA recognition motif - - - 0.000000000000000000000000000000009154 132.0
HKD1_k127_5252564_5 Yip1 domain - - - 0.000000008146 65.0
HKD1_k127_5252564_6 SnoaL-like domain - - - 0.00000479 55.0
HKD1_k127_5308916_0 Belongs to the peptidase M28 family - - - 0.0004539 54.0
HKD1_k127_5321224_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 3.062e-219 725.0
HKD1_k127_5321224_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.092e-201 638.0
HKD1_k127_5321224_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 330.0
HKD1_k127_5321224_11 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 334.0
HKD1_k127_5321224_12 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 336.0
HKD1_k127_5321224_13 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 323.0
HKD1_k127_5321224_14 electron transfer flavoprotein beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 316.0
HKD1_k127_5321224_15 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
HKD1_k127_5321224_16 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 302.0
HKD1_k127_5321224_17 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 295.0
HKD1_k127_5321224_18 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000419 282.0
HKD1_k127_5321224_19 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001782 276.0
HKD1_k127_5321224_2 Enoyl-CoA hydratase/isomerase - - - 4.587e-195 631.0
HKD1_k127_5321224_20 Alkyl hydroperoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
HKD1_k127_5321224_21 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000009748 241.0
HKD1_k127_5321224_22 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000008314 229.0
HKD1_k127_5321224_23 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000002137 232.0
HKD1_k127_5321224_24 Pilus assembly protein PilZ K02676 - - 0.0000000000000000000000000000000000000000000000001218 179.0
HKD1_k127_5321224_25 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000002531 180.0
HKD1_k127_5321224_26 General Secretion Pathway protein K02456 - - 0.0000000000000000000000000000000000000000000001547 175.0
HKD1_k127_5321224_27 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000005519 178.0
HKD1_k127_5321224_28 Thioredoxin-like - - - 0.000000000000000000000000000000000000002859 152.0
HKD1_k127_5321224_29 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000001075 142.0
HKD1_k127_5321224_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 574.0
HKD1_k127_5321224_30 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000004236 124.0
HKD1_k127_5321224_31 Type II secretion system (T2SS), protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000000009028 134.0
HKD1_k127_5321224_32 Transcriptional regulator K21747 - - 0.0000000000000000000000000002067 128.0
HKD1_k127_5321224_33 proteolysis - - - 0.0000000000000000000000000007974 121.0
HKD1_k127_5321224_34 Spore Coat Protein U domain - - - 0.0000000000000000000000001621 121.0
HKD1_k127_5321224_35 GspL periplasmic domain - - - 0.000000000000000000000003478 116.0
HKD1_k127_5321224_36 Domain of unknown function (DUF4266) - - - 0.00000000000000000000005303 103.0
HKD1_k127_5321224_37 Type II transport protein GspH K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000006439 104.0
HKD1_k127_5321224_38 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.00000000000000005443 93.0
HKD1_k127_5321224_39 secreted protein - - - 0.00000000000000007471 87.0
HKD1_k127_5321224_4 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 494.0
HKD1_k127_5321224_40 MTH538 TIR-like domain (DUF1863) - - - 0.00000000002488 70.0
HKD1_k127_5321224_41 Type II secretion system, protein N K02463 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000324 64.0
HKD1_k127_5321224_42 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.00000009765 64.0
HKD1_k127_5321224_43 PFAM type II secretion system protein I J K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000001114 60.0
HKD1_k127_5321224_44 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.00008771 51.0
HKD1_k127_5321224_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 437.0
HKD1_k127_5321224_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
HKD1_k127_5321224_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 394.0
HKD1_k127_5321224_8 outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 373.0
HKD1_k127_5321224_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 349.0
HKD1_k127_5359999_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 2.436e-242 795.0
HKD1_k127_5359999_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 7.744e-195 628.0
HKD1_k127_5359999_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 289.0
HKD1_k127_5359999_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 309.0
HKD1_k127_5359999_4 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000005135 229.0
HKD1_k127_5382214_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1686.0
HKD1_k127_5382214_1 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 1.25e-237 745.0
HKD1_k127_5382214_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000009003 254.0
HKD1_k127_5395167_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 555.0
HKD1_k127_5395167_1 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 544.0
HKD1_k127_5395167_2 PFAM Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 320.0
HKD1_k127_5395167_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003298 285.0
HKD1_k127_5395167_4 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000000000001483 128.0
HKD1_k127_5395167_5 Protein of unknown function (DUF3185) - - - 0.000000000005866 69.0
HKD1_k127_5395167_6 WD domain, G-beta repeat - - - 0.00000155 61.0
HKD1_k127_5407634_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009395 252.0
HKD1_k127_5407634_1 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000004855 230.0
HKD1_k127_5407634_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000006955 146.0
HKD1_k127_5407634_3 methyltransferase - - - 0.000000000000003705 79.0
HKD1_k127_5408545_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.241e-194 611.0
HKD1_k127_5408545_1 Belongs to the peptidase S1C family K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 291.0
HKD1_k127_5408545_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000005454 265.0
HKD1_k127_5408545_3 Stringent starvation protein A K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
HKD1_k127_5408545_4 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000282 273.0
HKD1_k127_5408545_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000002221 246.0
HKD1_k127_5408545_6 Stringent starvation protein B K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.0000000000000000000000000000000003241 143.0
HKD1_k127_5408545_7 Belongs to the UPF0102 family K07460 - - 0.0000000000000000001047 98.0
HKD1_k127_5408545_8 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000381 76.0
HKD1_k127_5431061_0 DNA helicase - - - 5.457e-309 991.0
HKD1_k127_5431061_1 ATP-dependent helicase K03579 - 3.6.4.13 8.677e-256 814.0
HKD1_k127_5431061_10 Cellulose biosynthesis protein BcsQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003989 254.0
HKD1_k127_5431061_11 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000004122 249.0
HKD1_k127_5431061_12 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000009915 245.0
HKD1_k127_5431061_13 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000001086 230.0
HKD1_k127_5431061_14 Domain of unknown function (DUF1971) - - - 0.000000000000000000000000000000000000000000000000000000003927 205.0
HKD1_k127_5431061_15 Oxalate decarboxylase - - - 0.00000000000000000000000000000000000000000026 162.0
HKD1_k127_5431061_16 endonuclease activity - - - 0.0000000000000000000000000000000000000127 150.0
HKD1_k127_5431061_17 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000005287 145.0
HKD1_k127_5431061_18 MazG-like family - - - 0.0000000000000000000000000000000000002811 149.0
HKD1_k127_5431061_19 metal cluster binding K06940 - - 0.0000000000000000000000000000000000006089 158.0
HKD1_k127_5431061_2 LVIVD repeat - - - 7.391e-213 669.0
HKD1_k127_5431061_20 - - - - 0.0000000000000000000000000000004052 134.0
HKD1_k127_5431061_21 Belongs to the UPF0237 family K07166 - - 0.000000000000000000000000000009146 121.0
HKD1_k127_5431061_22 CHAD domain containing protein - - - 0.0000000000000000000000000001194 128.0
HKD1_k127_5431061_23 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000006687 116.0
HKD1_k127_5431061_24 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000776 118.0
HKD1_k127_5431061_25 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000002597 103.0
HKD1_k127_5431061_26 - - - - 0.00000000000000000004278 98.0
HKD1_k127_5431061_27 - - - - 0.0000000000000000002179 93.0
HKD1_k127_5431061_28 Domain of unknown function (DUF1840) - - - 0.0000000000000000004468 92.0
HKD1_k127_5431061_29 - - - - 0.000000000000000004974 84.0
HKD1_k127_5431061_3 UPF0210 protein K09157 - - 2.371e-210 663.0
HKD1_k127_5431061_30 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000002212 90.0
HKD1_k127_5431061_31 - - - - 0.0000000000000007947 89.0
HKD1_k127_5431061_32 membrane - - - 0.000000000000003404 80.0
HKD1_k127_5431061_33 - - - - 0.0000000000001566 81.0
HKD1_k127_5431061_36 Glycine zipper 2TM domain - - - 0.0000000002417 68.0
HKD1_k127_5431061_4 RecA-superfamily ATPases implicated in signal transduction K08482 - - 1.577e-200 641.0
HKD1_k127_5431061_5 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 563.0
HKD1_k127_5431061_6 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 475.0
HKD1_k127_5431061_7 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 453.0
HKD1_k127_5431061_8 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 452.0
HKD1_k127_5431061_9 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 332.0
HKD1_k127_5502712_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.868e-264 823.0
HKD1_k127_5502712_1 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 608.0
HKD1_k127_5502712_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 589.0
HKD1_k127_5502712_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 443.0
HKD1_k127_5502712_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 336.0
HKD1_k127_5502712_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002481 289.0
HKD1_k127_5502712_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000008838 256.0
HKD1_k127_5502712_7 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000003839 200.0
HKD1_k127_5502712_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000001499 89.0
HKD1_k127_5502712_9 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000007451 85.0
HKD1_k127_5530652_0 PFAM glycoside hydrolase 15-related K01178 - 3.2.1.3 1.1e-322 1015.0
HKD1_k127_5530652_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 585.0
HKD1_k127_5530652_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009365 235.0
HKD1_k127_5530652_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000449 200.0
HKD1_k127_5530652_12 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000003008 186.0
HKD1_k127_5530652_13 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000002489 165.0
HKD1_k127_5530652_14 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000003043 152.0
HKD1_k127_5530652_15 - - - - 0.000000000000000000000000000000003233 132.0
HKD1_k127_5530652_2 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 375.0
HKD1_k127_5530652_3 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 361.0
HKD1_k127_5530652_4 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 363.0
HKD1_k127_5530652_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 351.0
HKD1_k127_5530652_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005952 301.0
HKD1_k127_5530652_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006289 282.0
HKD1_k127_5530652_8 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005013 273.0
HKD1_k127_5530652_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000852 254.0
HKD1_k127_5541062_0 Alpha-amylase domain K01187 - 3.2.1.20 0.0 1343.0
HKD1_k127_5541062_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 6.613e-240 752.0
HKD1_k127_5541062_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000002214 171.0
HKD1_k127_5547309_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.66e-321 1016.0
HKD1_k127_5547309_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.036e-230 726.0
HKD1_k127_5547309_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 309.0
HKD1_k127_5547309_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 287.0
HKD1_k127_5547309_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004048 275.0
HKD1_k127_5547309_13 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002898 243.0
HKD1_k127_5547309_14 Transcriptional K03719 - - 0.00000000000000000000000000000000000000000000000000000000000001131 220.0
HKD1_k127_5547309_15 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000004424 204.0
HKD1_k127_5547309_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000008059 171.0
HKD1_k127_5547309_17 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000058 140.0
HKD1_k127_5547309_18 Domain of unknown function (DUF4389) - - - 0.000000000000000000000183 100.0
HKD1_k127_5547309_19 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000006731 102.0
HKD1_k127_5547309_2 Aminotransferase class I and II K00812 - 2.6.1.1 1.406e-212 670.0
HKD1_k127_5547309_20 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000003028 82.0
HKD1_k127_5547309_21 - - - - 0.000000000000004009 80.0
HKD1_k127_5547309_22 - - - - 0.000000002296 62.0
HKD1_k127_5547309_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000001374 62.0
HKD1_k127_5547309_24 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000001414 68.0
HKD1_k127_5547309_3 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 562.0
HKD1_k127_5547309_4 Lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 549.0
HKD1_k127_5547309_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 495.0
HKD1_k127_5547309_6 glucose galactose transporter K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 464.0
HKD1_k127_5547309_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 435.0
HKD1_k127_5547309_8 Major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 372.0
HKD1_k127_5547309_9 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 314.0
HKD1_k127_555922_0 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 417.0
HKD1_k127_555922_1 Beta-lactamase K18988 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000001401 203.0
HKD1_k127_555922_2 - - - - 0.0000000000000000000000000000000000000000000000000001047 198.0
HKD1_k127_555922_3 FR47-like protein K06976 - - 0.0000000000000000000000000000000000002166 152.0
HKD1_k127_5587785_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 8.368e-210 657.0
HKD1_k127_5587785_1 DNA polymerase X family K02347 - - 7.009e-204 654.0
HKD1_k127_5587785_10 - - - - 0.000000000000000000000000000009838 126.0
HKD1_k127_5587785_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000001367 123.0
HKD1_k127_5587785_12 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000005922 122.0
HKD1_k127_5587785_13 - - - - 0.0000000000000000000000000193 119.0
HKD1_k127_5587785_14 GDSL-like Lipase/Acylhydrolase - - - 0.00000000001455 76.0
HKD1_k127_5587785_15 BON domain - - - 0.00001362 51.0
HKD1_k127_5587785_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 366.0
HKD1_k127_5587785_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 310.0
HKD1_k127_5587785_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
HKD1_k127_5587785_5 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 295.0
HKD1_k127_5587785_6 Belongs to the BI1 family K06890,K19416 - - 0.00000000000000000000000000000000000000000000000000000000006166 212.0
HKD1_k127_5587785_7 THUMP - - - 0.00000000000000000000000000000000000000000000000006773 184.0
HKD1_k127_5587785_8 Regulatory protein recX K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.00000000000000000000000000000000004765 140.0
HKD1_k127_5587785_9 YCII-related domain - - - 0.000000000000000000000000000000001696 135.0
HKD1_k127_5621355_0 FAD linked oxidase domain protein K05797 - 1.17.99.1 5.789e-215 681.0
HKD1_k127_5621355_1 DNA topological change - - - 2.025e-210 680.0
HKD1_k127_5621355_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 419.0
HKD1_k127_5621355_3 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 266.0
HKD1_k127_5621355_4 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000004659 218.0
HKD1_k127_5621355_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000001311 117.0
HKD1_k127_5621355_6 Belongs to the UPF0235 family K09131 - - 0.00000000003515 69.0
HKD1_k127_5621355_7 Bacterial regulatory proteins, tetR family - - - 0.00005236 53.0
HKD1_k127_5651425_0 GMC oxidoreductase K06151,K08261,K19813 - 1.1.5.9,1.1.99.21,1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 565.0
HKD1_k127_5651425_1 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 545.0
HKD1_k127_5651425_10 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001479 245.0
HKD1_k127_5651425_11 COG0811 Biopolymer transport proteins - - - 0.00000000000000000000000000000000000000000000000000000000004046 214.0
HKD1_k127_5651425_12 - - - - 0.000000000000000000000000000000000000000005278 166.0
HKD1_k127_5651425_13 Metal-sensitive transcriptional repressor K07807 - - 0.000000000000000000000000000000000005802 151.0
HKD1_k127_5651425_14 - - - - 0.000000000000000000000001029 108.0
HKD1_k127_5651425_15 - - - - 0.000000000000000000008707 105.0
HKD1_k127_5651425_16 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000889 87.0
HKD1_k127_5651425_17 - - - - 0.0000000000000002887 88.0
HKD1_k127_5651425_18 peptidase M23 - - - 0.0000000000001105 72.0
HKD1_k127_5651425_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 554.0
HKD1_k127_5651425_20 - - - - 0.00001096 50.0
HKD1_k127_5651425_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 360.0
HKD1_k127_5651425_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 344.0
HKD1_k127_5651425_5 Cytochrome C biogenesis protein transmembrane region K08970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 334.0
HKD1_k127_5651425_6 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 321.0
HKD1_k127_5651425_7 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 304.0
HKD1_k127_5651425_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008057 263.0
HKD1_k127_5651425_9 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000004306 229.0
HKD1_k127_57525_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 6.76e-226 716.0
HKD1_k127_57525_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 611.0
HKD1_k127_57525_10 HDOD domain - - - 0.000000000000000000000000000000000000000000002239 177.0
HKD1_k127_57525_11 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000001281 149.0
HKD1_k127_57525_12 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000007685 146.0
HKD1_k127_57525_13 Transcriptional regulator K07727 - - 0.000000000000000000000000002276 112.0
HKD1_k127_57525_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000005092 111.0
HKD1_k127_57525_15 FAD binding domain - - - 0.0000000000000000005476 98.0
HKD1_k127_57525_16 Protein of unknown function (DUF2975) - - - 0.0000000000000001236 87.0
HKD1_k127_57525_17 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0000000006291 61.0
HKD1_k127_57525_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 428.0
HKD1_k127_57525_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 421.0
HKD1_k127_57525_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 408.0
HKD1_k127_57525_5 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 370.0
HKD1_k127_57525_6 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 367.0
HKD1_k127_57525_7 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000001826 234.0
HKD1_k127_57525_8 - - - - 0.0000000000000000000000000000000000000000000000000000000004779 210.0
HKD1_k127_57525_9 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000004921 207.0
HKD1_k127_5765823_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - 4.546e-300 931.0
HKD1_k127_5765823_1 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 584.0
HKD1_k127_5765823_10 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000004845 160.0
HKD1_k127_5765823_11 SnoaL-like domain - - - 0.00000000000000000000000000001374 120.0
HKD1_k127_5765823_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000002727 116.0
HKD1_k127_5765823_13 - - - - 0.00000000000000000002059 98.0
HKD1_k127_5765823_14 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000000006333 83.0
HKD1_k127_5765823_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 456.0
HKD1_k127_5765823_3 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 366.0
HKD1_k127_5765823_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 317.0
HKD1_k127_5765823_5 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 291.0
HKD1_k127_5765823_6 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 265.0
HKD1_k127_5765823_7 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000549 230.0
HKD1_k127_5765823_8 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000007303 226.0
HKD1_k127_5765823_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000001181 208.0
HKD1_k127_580046_0 TonB dependent receptor K02014 - - 6.715e-310 970.0
HKD1_k127_580046_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 9.612e-297 931.0
HKD1_k127_580046_10 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007013 258.0
HKD1_k127_580046_11 Transcriptional regulatory protein, C terminal K07667 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000001192 255.0
HKD1_k127_580046_12 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000002947 228.0
HKD1_k127_580046_13 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000002513 171.0
HKD1_k127_580046_14 ATPase activity K02045 - 3.6.3.25 0.0006089 44.0
HKD1_k127_580046_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 2.126e-290 915.0
HKD1_k127_580046_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 4.885e-266 833.0
HKD1_k127_580046_4 Histidine kinase K07646 - 2.7.13.3 9.871e-253 807.0
HKD1_k127_580046_5 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 602.0
HKD1_k127_580046_6 Magnesium transport protein CorA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 567.0
HKD1_k127_580046_7 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 515.0
HKD1_k127_580046_8 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 483.0
HKD1_k127_580046_9 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 349.0
HKD1_k127_5980240_0 Major Facilitator Superfamily - - - 3.012e-205 657.0
HKD1_k127_5980240_1 Dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 612.0
HKD1_k127_5980240_10 Cytochrome c K17760 - 1.1.9.1 0.0000000000005094 74.0
HKD1_k127_5980240_2 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 318.0
HKD1_k127_5980240_3 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000001167 239.0
HKD1_k127_5980240_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000002751 237.0
HKD1_k127_5980240_5 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000001358 213.0
HKD1_k127_5980240_6 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
HKD1_k127_5980240_7 - - - - 0.00000000000000000000000000000000000000000000000000000005583 212.0
HKD1_k127_5980240_8 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000001234 163.0
HKD1_k127_5980240_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000001856 147.0
HKD1_k127_60091_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 445.0
HKD1_k127_60091_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 435.0
HKD1_k127_60091_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002211 260.0
HKD1_k127_60091_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000005256 166.0
HKD1_k127_60091_4 - - - - 0.000000000000000001142 98.0
HKD1_k127_60091_5 - - - - 0.00000000000001631 87.0
HKD1_k127_60091_6 - - - - 0.00000000001145 68.0
HKD1_k127_6080285_0 Cytochrome c K02198 - - 5.733e-226 718.0
HKD1_k127_6080285_1 Major facilitator superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 516.0
HKD1_k127_6080285_10 Protein of unknown function (DUF3450) - - - 0.000000000000000000000000000000000000000000000000000000000000006389 226.0
HKD1_k127_6080285_11 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000005372 232.0
HKD1_k127_6080285_12 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000002577 206.0
HKD1_k127_6080285_13 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000004112 190.0
HKD1_k127_6080285_14 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000002218 182.0
HKD1_k127_6080285_15 TIGRFAM periplasmic protein K02199 - - 0.00000000000000000000000000000000000000000000000007693 185.0
HKD1_k127_6080285_16 phosphate regulon transcriptional regulatory protein PhoB K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000001806 171.0
HKD1_k127_6080285_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000002961 165.0
HKD1_k127_6080285_18 Protein of unknown function (DUF3450) - - - 0.0000000000000000000000000000000000000000001363 169.0
HKD1_k127_6080285_19 - - - - 0.00000000000000000000000000000000000001711 148.0
HKD1_k127_6080285_2 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 407.0
HKD1_k127_6080285_20 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000001657 147.0
HKD1_k127_6080285_21 Cytochrome C biogenesis K02200 - - 0.0000000000000000000000000000000000185 148.0
HKD1_k127_6080285_22 Cytochrome C' - - - 0.00000000000000000000000000000000004989 141.0
HKD1_k127_6080285_23 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000002137 139.0
HKD1_k127_6080285_24 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000003153 130.0
HKD1_k127_6080285_25 subunit of a heme lyase K02200,K04017 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.00000000000000000000000000003205 129.0
HKD1_k127_6080285_26 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000004672 124.0
HKD1_k127_6080285_27 - - - - 0.000000000000000000000004053 112.0
HKD1_k127_6080285_28 PFAM Forkhead-associated protein - - - 0.000000003028 69.0
HKD1_k127_6080285_29 NAD ADP-ribosyltransferase activity. It is involved in the biological process described with protein ADP-ribosylation K10798 GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251 2.4.2.30 0.000002612 57.0
HKD1_k127_6080285_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 388.0
HKD1_k127_6080285_30 AAA domain - - - 0.00000607 58.0
HKD1_k127_6080285_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 377.0
HKD1_k127_6080285_5 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 380.0
HKD1_k127_6080285_6 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 366.0
HKD1_k127_6080285_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001606 290.0
HKD1_k127_6080285_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009593 289.0
HKD1_k127_6080285_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000945 262.0
HKD1_k127_6082549_0 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 7.087e-242 777.0
HKD1_k127_6082549_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.353e-199 634.0
HKD1_k127_6082549_10 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001355 232.0
HKD1_k127_6082549_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000005889 211.0
HKD1_k127_6082549_12 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000001072 196.0
HKD1_k127_6082549_13 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000003464 175.0
HKD1_k127_6082549_14 - - - - 0.00000000000000000000000000000000000000000001706 172.0
HKD1_k127_6082549_15 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000004462 164.0
HKD1_k127_6082549_16 - - - - 0.000000000000000000000000000000000000000002228 170.0
HKD1_k127_6082549_17 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000007411 156.0
HKD1_k127_6082549_18 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000009025 151.0
HKD1_k127_6082549_19 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000001056 119.0
HKD1_k127_6082549_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 584.0
HKD1_k127_6082549_20 - - - - 0.0000000000000000000000004039 110.0
HKD1_k127_6082549_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000001038 91.0
HKD1_k127_6082549_22 Protein kinase domain K12132 - 2.7.11.1 0.000000000000001984 80.0
HKD1_k127_6082549_23 secretion system protein K02453 - - 0.0000000000001412 79.0
HKD1_k127_6082549_24 COGs COG5616 integral membrane protein - - - 0.000002237 60.0
HKD1_k127_6082549_25 SnoaL-like domain - - - 0.0002885 53.0
HKD1_k127_6082549_3 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 522.0
HKD1_k127_6082549_4 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 473.0
HKD1_k127_6082549_5 Ferredoxin-fold anticodon binding domain K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 423.0
HKD1_k127_6082549_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 349.0
HKD1_k127_6082549_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 310.0
HKD1_k127_6082549_8 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001067 300.0
HKD1_k127_6082549_9 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000008764 250.0
HKD1_k127_6088645_0 Efflux pump membrane transporter K18299,K18902 - - 0.0 1206.0
HKD1_k127_6088645_1 xanthine dehydrogenase activity - - - 0.0 1045.0
HKD1_k127_6088645_10 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 324.0
HKD1_k127_6088645_11 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 301.0
HKD1_k127_6088645_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 294.0
HKD1_k127_6088645_13 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
HKD1_k127_6088645_14 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001157 258.0
HKD1_k127_6088645_15 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000673 266.0
HKD1_k127_6088645_16 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000002307 238.0
HKD1_k127_6088645_17 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000006953 235.0
HKD1_k127_6088645_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000112 214.0
HKD1_k127_6088645_19 - - - - 0.0000000000000000000000000000000000000000000000000003022 207.0
HKD1_k127_6088645_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 4.698e-318 1004.0
HKD1_k127_6088645_20 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000001435 175.0
HKD1_k127_6088645_21 Beta-lactamase - - - 0.000000000000000000000000000000000000000000006263 181.0
HKD1_k127_6088645_22 DnaK suppressor protein - - - 0.000000000000000000000000000000000001006 140.0
HKD1_k127_6088645_23 COG0457 FOG TPR repeat - - - 0.000000000000000000000000001842 128.0
HKD1_k127_6088645_24 - - - - 0.00000000000000000000003254 103.0
HKD1_k127_6088645_25 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000006978 108.0
HKD1_k127_6088645_26 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000002013 97.0
HKD1_k127_6088645_27 - - - - 0.0000000000000001094 93.0
HKD1_k127_6088645_28 PFAM Photosynthetic reaction centre cytochrome C subunit K13992 - - 0.0000000000000004314 92.0
HKD1_k127_6088645_29 Beta-lactamase - - - 0.00000000000001079 78.0
HKD1_k127_6088645_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.501e-266 837.0
HKD1_k127_6088645_31 - - - - 0.0000000000004312 81.0
HKD1_k127_6088645_4 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 8.107e-206 651.0
HKD1_k127_6088645_5 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 576.0
HKD1_k127_6088645_6 FAD linked oxidase domain protein K05797 - 1.17.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 552.0
HKD1_k127_6088645_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K18901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 370.0
HKD1_k127_6088645_8 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 339.0
HKD1_k127_6088645_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 317.0
HKD1_k127_6130662_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.993e-286 894.0
HKD1_k127_6130662_1 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 3.834e-266 905.0
HKD1_k127_6130662_10 Oxidoreductase FAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 355.0
HKD1_k127_6130662_11 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 340.0
HKD1_k127_6130662_12 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 356.0
HKD1_k127_6130662_13 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000007364 239.0
HKD1_k127_6130662_14 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000003223 220.0
HKD1_k127_6130662_15 response regulator receiver K02657 - - 0.000000000000000000000000000000000000000000000000000000000000539 217.0
HKD1_k127_6130662_16 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000003595 213.0
HKD1_k127_6130662_17 - - - - 0.000000000000000000000000000000000000000000000000000000000005461 217.0
HKD1_k127_6130662_18 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000008831 219.0
HKD1_k127_6130662_19 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000002762 209.0
HKD1_k127_6130662_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 495.0
HKD1_k127_6130662_20 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000009947 189.0
HKD1_k127_6130662_21 Iron-sulfur cluster insertion protein ErpA K15724 - - 0.00000000000000000000000000000000000000000000000005053 179.0
HKD1_k127_6130662_22 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000007803 171.0
HKD1_k127_6130662_23 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000116 162.0
HKD1_k127_6130662_24 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.00000000000000000000000000000000002477 147.0
HKD1_k127_6130662_25 Two component signalling adaptor domain K02659 - - 0.00000000000000000000000000000000004401 145.0
HKD1_k127_6130662_26 cell shape determination - - - 0.000000000000000000000000000001788 125.0
HKD1_k127_6130662_27 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000001285 111.0
HKD1_k127_6130662_28 - - - - 0.0000000000000000000008934 104.0
HKD1_k127_6130662_29 Two component signalling adaptor domain K06598 - - 0.000000000000000002611 97.0
HKD1_k127_6130662_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 419.0
HKD1_k127_6130662_30 Cysteine-rich CPXCG - - - 0.0000000000000233 79.0
HKD1_k127_6130662_31 - - - - 0.000000291 52.0
HKD1_k127_6130662_4 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
HKD1_k127_6130662_5 twitching motility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 419.0
HKD1_k127_6130662_6 chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 394.0
HKD1_k127_6130662_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 379.0
HKD1_k127_6130662_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 368.0
HKD1_k127_6130662_9 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 346.0
HKD1_k127_6134520_0 serine dehydratase beta chain K01752 - 4.3.1.17 7.487e-244 762.0
HKD1_k127_6134520_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 433.0
HKD1_k127_6134520_2 Asparaginase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 403.0
HKD1_k127_6134520_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 378.0
HKD1_k127_6134520_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001647 252.0
HKD1_k127_6134520_5 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000194 207.0
HKD1_k127_6134520_6 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000007741 101.0
HKD1_k127_6145126_0 Belongs to the peptidase M16 family K07263 - - 1.956e-298 945.0
HKD1_k127_6145126_1 E1-E2 ATPase K01535 - 3.6.3.6 1.93e-291 916.0
HKD1_k127_6145126_2 COG4993 Glucose dehydrogenase - - - 2.569e-219 700.0
HKD1_k127_6145126_3 glutathione s-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002151 277.0
HKD1_k127_6145126_4 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000001175 210.0
HKD1_k127_6145126_5 NHL repeat - - - 0.0000000000000000000000000000009768 133.0
HKD1_k127_6192886_0 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 527.0
HKD1_k127_6192886_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 508.0
HKD1_k127_6192886_2 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
HKD1_k127_6192886_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000006711 232.0
HKD1_k127_6192886_4 - - - - 0.000000000001275 75.0
HKD1_k127_6192886_5 PFAM PBS lyase HEAT domain protein - - - 0.000000000003791 76.0
HKD1_k127_6192886_6 Domain of unknown function DUF11 - - - 0.0000009882 60.0
HKD1_k127_6192886_7 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.00002989 55.0
HKD1_k127_6207337_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.961e-293 925.0
HKD1_k127_6207337_1 PQQ enzyme repeat K00114 - 1.1.2.8 5.917e-243 767.0
HKD1_k127_6207337_10 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 333.0
HKD1_k127_6207337_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 300.0
HKD1_k127_6207337_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 299.0
HKD1_k127_6207337_13 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000001594 238.0
HKD1_k127_6207337_14 - - - - 0.00000000000000000000000000000000000000000000000000000002932 213.0
HKD1_k127_6207337_15 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000009202 205.0
HKD1_k127_6207337_16 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000009334 197.0
HKD1_k127_6207337_17 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000007133 194.0
HKD1_k127_6207337_18 Belongs to the UPF0311 family - - - 0.000000000000000000000000000000000000000000000000001073 194.0
HKD1_k127_6207337_19 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000008243 188.0
HKD1_k127_6207337_2 Participates in both transcription termination and antitermination K02600 - - 1.65e-216 682.0
HKD1_k127_6207337_20 heme binding K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000001251 191.0
HKD1_k127_6207337_21 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000009205 144.0
HKD1_k127_6207337_22 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000009271 148.0
HKD1_k127_6207337_23 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000005268 93.0
HKD1_k127_6207337_24 Rieske [2Fe-2S] domain - - - 0.0000000000000001211 81.0
HKD1_k127_6207337_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 536.0
HKD1_k127_6207337_4 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 475.0
HKD1_k127_6207337_5 Belongs to the beta-ketoacyl-ACP synthases family K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 462.0
HKD1_k127_6207337_6 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 432.0
HKD1_k127_6207337_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 402.0
HKD1_k127_6207337_8 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 364.0
HKD1_k127_6207337_9 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 336.0
HKD1_k127_6211055_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1140.0
HKD1_k127_6211055_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 604.0
HKD1_k127_6211055_10 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001573 235.0
HKD1_k127_6211055_11 - - - - 0.00000000000000000000000000000000000000000000000000000118 214.0
HKD1_k127_6211055_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000007074 197.0
HKD1_k127_6211055_13 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000003286 154.0
HKD1_k127_6211055_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000002808 129.0
HKD1_k127_6211055_15 - - - - 0.0000000000000000000000012 115.0
HKD1_k127_6211055_2 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 511.0
HKD1_k127_6211055_3 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 474.0
HKD1_k127_6211055_4 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 477.0
HKD1_k127_6211055_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 446.0
HKD1_k127_6211055_6 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 416.0
HKD1_k127_6211055_7 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 326.0
HKD1_k127_6211055_8 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 299.0
HKD1_k127_6211055_9 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 270.0
HKD1_k127_6271081_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 8.514e-280 869.0
HKD1_k127_6271081_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 6.978e-261 831.0
HKD1_k127_6271081_10 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 379.0
HKD1_k127_6271081_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 353.0
HKD1_k127_6271081_12 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 350.0
HKD1_k127_6271081_13 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 338.0
HKD1_k127_6271081_14 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 336.0
HKD1_k127_6271081_15 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 342.0
HKD1_k127_6271081_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 311.0
HKD1_k127_6271081_17 Two component response regulator for the phosphate regulon K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 306.0
HKD1_k127_6271081_18 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 293.0
HKD1_k127_6271081_19 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 299.0
HKD1_k127_6271081_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 612.0
HKD1_k127_6271081_20 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000759 276.0
HKD1_k127_6271081_21 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000174 234.0
HKD1_k127_6271081_22 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001148 239.0
HKD1_k127_6271081_23 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.00000000000000000000000000000000000000000008399 164.0
HKD1_k127_6271081_24 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000001282 174.0
HKD1_k127_6271081_25 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000001733 164.0
HKD1_k127_6271081_26 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000005586 158.0
HKD1_k127_6271081_27 Belongs to the skp family K06142 - - 0.00000000000000000000000003145 117.0
HKD1_k127_6271081_28 TIGRFAM conserved repeat domain - - - 0.0000000000000003218 88.0
HKD1_k127_6271081_29 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000397 81.0
HKD1_k127_6271081_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 606.0
HKD1_k127_6271081_4 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 571.0
HKD1_k127_6271081_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 433.0
HKD1_k127_6271081_6 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 428.0
HKD1_k127_6271081_7 Belongs to the transferase hexapeptide repeat family K00674 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 419.0
HKD1_k127_6271081_8 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 406.0
HKD1_k127_6271081_9 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 404.0
HKD1_k127_6310720_0 Adenylate cyclase - - - 9.666e-237 750.0
HKD1_k127_6310720_1 oxidase, subunit K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 567.0
HKD1_k127_6310720_10 - - - - 0.000000000000000434 81.0
HKD1_k127_6310720_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 502.0
HKD1_k127_6310720_3 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 387.0
HKD1_k127_6310720_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 352.0
HKD1_k127_6310720_5 Lipoprotein releasing system transmembrane protein K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000406 226.0
HKD1_k127_6310720_6 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000001256 231.0
HKD1_k127_6310720_7 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000014 161.0
HKD1_k127_6310720_8 - - - - 0.00000000000000000000000000000001195 132.0
HKD1_k127_6310720_9 Winged helix DNA-binding domain - - - 0.0000000000000002013 85.0
HKD1_k127_6316265_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 606.0
HKD1_k127_6316265_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002266 246.0
HKD1_k127_6316265_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002743 216.0
HKD1_k127_6316265_3 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000002493 215.0
HKD1_k127_6316265_4 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000002703 174.0
HKD1_k127_6321799_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 3.503e-265 831.0
HKD1_k127_6321799_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 3.316e-241 752.0
HKD1_k127_6321799_10 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001351 259.0
HKD1_k127_6321799_11 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000001986 118.0
HKD1_k127_6321799_12 TIGRFAM methyltransferase FkbM family - - - 0.00000000000000000000008069 105.0
HKD1_k127_6321799_13 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000000000000006908 83.0
HKD1_k127_6321799_14 amidohydrolase - - - 0.00000000000004198 80.0
HKD1_k127_6321799_15 MarR family - - - 0.00002984 52.0
HKD1_k127_6321799_2 Protein of unknown function (DUF1593) - - - 1.511e-201 641.0
HKD1_k127_6321799_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 541.0
HKD1_k127_6321799_4 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 432.0
HKD1_k127_6321799_5 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 342.0
HKD1_k127_6321799_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 346.0
HKD1_k127_6321799_7 ATPases associated with a variety of cellular activities K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 323.0
HKD1_k127_6321799_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 334.0
HKD1_k127_6321799_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001715 250.0
HKD1_k127_6468602_0 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 539.0
HKD1_k127_6468602_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 464.0
HKD1_k127_6468602_10 decarboxylase K01607 - 4.1.1.44 0.000000000009323 74.0
HKD1_k127_6468602_2 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 394.0
HKD1_k127_6468602_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 376.0
HKD1_k127_6468602_4 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 348.0
HKD1_k127_6468602_5 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 336.0
HKD1_k127_6468602_6 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001043 281.0
HKD1_k127_6468602_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000008318 126.0
HKD1_k127_6468602_8 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000002801 123.0
HKD1_k127_6468602_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000007341 103.0
HKD1_k127_65001_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.205e-310 972.0
HKD1_k127_65001_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 624.0
HKD1_k127_65001_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 540.0
HKD1_k127_65001_3 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 406.0
HKD1_k127_6508400_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 574.0
HKD1_k127_6508400_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 309.0
HKD1_k127_6559046_0 ABC transporter K06147,K06148 - - 6.869e-247 779.0
HKD1_k127_6559046_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 400.0
HKD1_k127_6559046_2 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
HKD1_k127_6559046_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001368 266.0
HKD1_k127_6559046_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000001431 237.0
HKD1_k127_6559046_5 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000002777 117.0
HKD1_k127_6559046_6 - - - - 0.00000374 53.0
HKD1_k127_6575135_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1049.0
HKD1_k127_6575135_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 2.537e-300 962.0
HKD1_k127_6575135_10 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 302.0
HKD1_k127_6575135_11 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003927 271.0
HKD1_k127_6575135_12 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003599 254.0
HKD1_k127_6575135_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000002913 203.0
HKD1_k127_6575135_14 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000000002938 177.0
HKD1_k127_6575135_15 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000003456 165.0
HKD1_k127_6575135_16 - - - - 0.000000000000000000000000000000004634 137.0
HKD1_k127_6575135_17 Putative phage abortive infection protein - - - 0.000000000000000000000000000000004759 139.0
HKD1_k127_6575135_18 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000002473 110.0
HKD1_k127_6575135_19 Protein of unknown function (DUF1328) - - - 0.000000000001237 73.0
HKD1_k127_6575135_2 Glycosyl hydrolases family 15 - - - 1.815e-285 892.0
HKD1_k127_6575135_20 PFAM PRC-barrel domain - - - 0.0000733 53.0
HKD1_k127_6575135_21 PFAM Prokaryotic metallothionein K21904 - - 0.00008172 47.0
HKD1_k127_6575135_22 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 0.0003777 48.0
HKD1_k127_6575135_3 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 2.453e-228 734.0
HKD1_k127_6575135_4 Alpha amylase, catalytic domain K01236 - 3.2.1.141 2.209e-194 635.0
HKD1_k127_6575135_5 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 490.0
HKD1_k127_6575135_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 445.0
HKD1_k127_6575135_7 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 426.0
HKD1_k127_6575135_8 RHS Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 428.0
HKD1_k127_6575135_9 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 398.0
HKD1_k127_66119_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 287.0
HKD1_k127_66119_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HKD1_k127_66119_2 NHL repeat - - - 0.00000000000000000000000000001312 121.0
HKD1_k127_69230_0 2 iron, 2 sulfur cluster binding - - - 0.0 1627.0
HKD1_k127_69230_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1348.0
HKD1_k127_69230_10 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000008055 164.0
HKD1_k127_69230_2 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 0.0 1094.0
HKD1_k127_69230_3 Bacterial protein of unknown function (DUF885) - - - 2.056e-227 720.0
HKD1_k127_69230_4 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 535.0
HKD1_k127_69230_5 transmembrane transporter activity K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 435.0
HKD1_k127_69230_6 Putative vitamin uptake transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 360.0
HKD1_k127_69230_7 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000009008 210.0
HKD1_k127_69230_8 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000001415 196.0
HKD1_k127_69230_9 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000009022 183.0
HKD1_k127_7054580_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 6.022e-231 724.0
HKD1_k127_7054580_1 SMART Elongator protein 3 MiaB NifB - - - 1.273e-226 712.0
HKD1_k127_7054580_10 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006911 284.0
HKD1_k127_7054580_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
HKD1_k127_7054580_12 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001478 284.0
HKD1_k127_7054580_13 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000001264 250.0
HKD1_k127_7054580_14 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000001579 195.0
HKD1_k127_7054580_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000001279 178.0
HKD1_k127_7054580_17 SnoaL-like domain - - - 0.0000000000007739 81.0
HKD1_k127_7054580_18 Glycine-zipper domain - - - 0.000000000002097 76.0
HKD1_k127_7054580_19 Sh3 type 3 domain protein K01361 - 3.4.21.96 0.00000000001041 71.0
HKD1_k127_7054580_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 7.38e-226 722.0
HKD1_k127_7054580_20 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000001639 72.0
HKD1_k127_7054580_21 Bacterial regulatory proteins, tetR family - - - 0.0000005539 52.0
HKD1_k127_7054580_3 MacB-like periplasmic core domain - - - 1.268e-212 686.0
HKD1_k127_7054580_4 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 556.0
HKD1_k127_7054580_5 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 551.0
HKD1_k127_7054580_6 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 543.0
HKD1_k127_7054580_7 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 376.0
HKD1_k127_7054580_8 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 359.0
HKD1_k127_7054580_9 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 340.0
HKD1_k127_7055593_0 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 2.208e-205 651.0
HKD1_k127_7055593_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 620.0
HKD1_k127_7055593_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000001204 147.0
HKD1_k127_7071654_0 efflux transmembrane transporter activity - - - 7.867e-199 647.0
HKD1_k127_7071654_1 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 589.0
HKD1_k127_7071654_10 RNA-binding - - - 0.00000000000000000000000000000006509 126.0
HKD1_k127_7071654_11 Sulfurtransferase - - - 0.000000000000000000000000000003586 128.0
HKD1_k127_7071654_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000002444 116.0
HKD1_k127_7071654_13 COG3245 Cytochrome c5 K02277 - 1.9.3.1 0.000000000000000000000001954 109.0
HKD1_k127_7071654_14 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000001242 76.0
HKD1_k127_7071654_15 OmpA-like transmembrane domain - - - 0.0000000000000133 82.0
HKD1_k127_7071654_16 Protein of unknown function (DUF3012) - - - 0.00000000000003301 74.0
HKD1_k127_7071654_17 - - - - 0.00000002748 65.0
HKD1_k127_7071654_18 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00008006 51.0
HKD1_k127_7071654_2 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 482.0
HKD1_k127_7071654_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 336.0
HKD1_k127_7071654_4 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 330.0
HKD1_k127_7071654_5 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002256 244.0
HKD1_k127_7071654_6 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000003197 237.0
HKD1_k127_7071654_7 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000007054 151.0
HKD1_k127_7071654_8 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000001725 147.0
HKD1_k127_7071654_9 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000337 129.0
HKD1_k127_7090064_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 5.907e-290 910.0
HKD1_k127_7090064_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 591.0
HKD1_k127_7090064_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 548.0
HKD1_k127_7090064_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 494.0
HKD1_k127_7090064_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 466.0
HKD1_k127_7090064_5 cystathione gamma lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 446.0
HKD1_k127_7090064_6 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 317.0
HKD1_k127_7090064_7 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000001814 267.0
HKD1_k127_7090064_8 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000001127 192.0
HKD1_k127_7090064_9 - - - - 0.00000000009083 64.0
HKD1_k127_7098179_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1512.0
HKD1_k127_7098179_1 ATPase (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 517.0
HKD1_k127_7098179_10 Glutathione S-transferase, N-terminal domain K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 308.0
HKD1_k127_7098179_11 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000005542 223.0
HKD1_k127_7098179_12 - - - - 0.0000000000000000000000000000000000000000000000000000002352 204.0
HKD1_k127_7098179_13 homocysteine K00547 - 2.1.1.10 0.000000000000000000000000000000000000006008 158.0
HKD1_k127_7098179_14 - - - - 0.000000000000000000000000002437 116.0
HKD1_k127_7098179_15 oxidoreductase activity K07114 - - 0.00000000000000001431 88.0
HKD1_k127_7098179_2 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 501.0
HKD1_k127_7098179_3 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 480.0
HKD1_k127_7098179_4 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 445.0
HKD1_k127_7098179_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 411.0
HKD1_k127_7098179_6 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 381.0
HKD1_k127_7098179_7 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 411.0
HKD1_k127_7098179_8 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 368.0
HKD1_k127_7098179_9 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 322.0
HKD1_k127_7110415_0 Bacterial protein of unknown function (DUF885) - - - 7.409e-224 713.0
HKD1_k127_7110415_1 Pyridine nucleotide-disulphide oxidoreductase - - - 7.066e-194 617.0
HKD1_k127_7110415_10 Ribbon-helix-helix protein, copG family - - - 0.0004488 47.0
HKD1_k127_7110415_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 467.0
HKD1_k127_7110415_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 411.0
HKD1_k127_7110415_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 378.0
HKD1_k127_7110415_5 Binding-protein-dependent transport system inner membrane component K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 339.0
HKD1_k127_7110415_6 transposition K07497 - - 0.000000000000000000000000000000000000000000000000001913 187.0
HKD1_k127_7110415_7 transposition K07497 - - 0.000000000000000000000005495 108.0
HKD1_k127_7110415_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000003921 75.0
HKD1_k127_7110415_9 - - - - 0.000000002296 62.0
HKD1_k127_7113196_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - 1.717e-244 780.0
HKD1_k127_7113196_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 510.0
HKD1_k127_7113196_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 328.0
HKD1_k127_7113196_11 COG3202 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 334.0
HKD1_k127_7113196_12 PFAM ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
HKD1_k127_7113196_13 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 295.0
HKD1_k127_7113196_14 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 291.0
HKD1_k127_7113196_15 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 302.0
HKD1_k127_7113196_16 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
HKD1_k127_7113196_17 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006526 272.0
HKD1_k127_7113196_18 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003577 285.0
HKD1_k127_7113196_19 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002196 262.0
HKD1_k127_7113196_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 482.0
HKD1_k127_7113196_20 serine-type endopeptidase activity K13908,K21125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005404 261.0
HKD1_k127_7113196_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000005329 243.0
HKD1_k127_7113196_22 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002036 241.0
HKD1_k127_7113196_23 cellular modified histidine biosynthetic process K18802 - - 0.000000000000000000000000000000000000000000000000000000000000001995 229.0
HKD1_k127_7113196_24 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000007268 234.0
HKD1_k127_7113196_25 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000002696 218.0
HKD1_k127_7113196_26 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000009682 209.0
HKD1_k127_7113196_27 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000001783 199.0
HKD1_k127_7113196_28 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000005159 166.0
HKD1_k127_7113196_29 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000006672 174.0
HKD1_k127_7113196_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 456.0
HKD1_k127_7113196_30 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000002084 171.0
HKD1_k127_7113196_32 Type II secretory pathway, pseudopilin PulG K10924 - - 0.000000000000000000004889 98.0
HKD1_k127_7113196_34 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000003634 82.0
HKD1_k127_7113196_35 small protein containing a coiled-coil domain - - - 0.00000000000002202 76.0
HKD1_k127_7113196_4 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 488.0
HKD1_k127_7113196_5 MCM2/3/5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 438.0
HKD1_k127_7113196_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 466.0
HKD1_k127_7113196_7 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 406.0
HKD1_k127_7113196_8 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 367.0
HKD1_k127_7113196_9 PFAM peptidase K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 326.0
HKD1_k127_7123483_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.78e-262 824.0
HKD1_k127_7123483_1 Protein tyrosine kinase - - - 6.203e-209 679.0
HKD1_k127_7123483_10 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000218 202.0
HKD1_k127_7123483_11 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000003467 169.0
HKD1_k127_7123483_12 Ion channel - - - 0.000000000000000000000001142 107.0
HKD1_k127_7123483_2 PFAM Type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 525.0
HKD1_k127_7123483_3 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 449.0
HKD1_k127_7123483_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 423.0
HKD1_k127_7123483_5 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 420.0
HKD1_k127_7123483_6 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 367.0
HKD1_k127_7123483_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 325.0
HKD1_k127_7123483_8 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006492 283.0
HKD1_k127_7123483_9 Rnf-Nqr subunit, membrane protein K03617 - - 0.000000000000000000000000000000000000000000000000000001892 202.0
HKD1_k127_7158431_0 Carbon starvation protein K06200 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0 1077.0
HKD1_k127_7158431_1 TIGRFAM FeS assembly protein SufB K09014 - - 1.288e-270 837.0
HKD1_k127_7158431_10 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 464.0
HKD1_k127_7158431_11 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 451.0
HKD1_k127_7158431_12 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 438.0
HKD1_k127_7158431_13 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 445.0
HKD1_k127_7158431_14 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 436.0
HKD1_k127_7158431_15 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 374.0
HKD1_k127_7158431_16 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 367.0
HKD1_k127_7158431_17 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 353.0
HKD1_k127_7158431_18 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 337.0
HKD1_k127_7158431_19 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 353.0
HKD1_k127_7158431_2 sulphate transporter - - - 2.259e-212 674.0
HKD1_k127_7158431_20 carbohydrate transport K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 313.0
HKD1_k127_7158431_21 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 306.0
HKD1_k127_7158431_22 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 311.0
HKD1_k127_7158431_23 PFAM MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 295.0
HKD1_k127_7158431_24 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005974 282.0
HKD1_k127_7158431_25 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009416 277.0
HKD1_k127_7158431_26 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002189 288.0
HKD1_k127_7158431_27 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008057 278.0
HKD1_k127_7158431_28 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003579 256.0
HKD1_k127_7158431_29 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002893 264.0
HKD1_k127_7158431_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 581.0
HKD1_k127_7158431_30 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002934 255.0
HKD1_k127_7158431_31 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006356 256.0
HKD1_k127_7158431_32 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009205 247.0
HKD1_k127_7158431_34 COG1360 Flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000983 228.0
HKD1_k127_7158431_35 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000008359 196.0
HKD1_k127_7158431_36 PFAM Amino acid-binding ACT K03567 - - 0.000000000000000000000000000000000000000000000000000002908 196.0
HKD1_k127_7158431_37 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000003057 184.0
HKD1_k127_7158431_38 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000001099 185.0
HKD1_k127_7158431_39 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000001295 183.0
HKD1_k127_7158431_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 543.0
HKD1_k127_7158431_40 - - - - 0.0000000000000000000000000000000000000000000000004746 186.0
HKD1_k127_7158431_41 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000000000000000000004387 149.0
HKD1_k127_7158431_42 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000009842 143.0
HKD1_k127_7158431_43 SH3 domain K07184 - - 0.000000000000000000000000000000000000401 148.0
HKD1_k127_7158431_44 HIT family K02503 - - 0.000000000000000000000000000000000003766 142.0
HKD1_k127_7158431_45 transcriptional regulator - - - 0.00000000000000000000000000000000001712 140.0
HKD1_k127_7158431_46 Protein of unknown function (DUF3302) - - - 0.00000000000000000000000000001205 127.0
HKD1_k127_7158431_47 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000002271 118.0
HKD1_k127_7158431_48 Universal stress protein K06149 - - 0.00000000000000000000000001179 115.0
HKD1_k127_7158431_49 - - - - 0.00000000000000000000000006644 116.0
HKD1_k127_7158431_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 536.0
HKD1_k127_7158431_50 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000007559 114.0
HKD1_k127_7158431_51 YceI-like domain - - - 0.00000000000000000000000007596 119.0
HKD1_k127_7158431_52 PFAM RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000006354 110.0
HKD1_k127_7158431_53 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000004758 102.0
HKD1_k127_7158431_54 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000172 96.0
HKD1_k127_7158431_55 Selenoprotein, putative - - - 0.00000000000000007963 83.0
HKD1_k127_7158431_56 Histidine kinase K02480 - 2.7.13.3 0.00000000000006192 81.0
HKD1_k127_7158431_57 ATP-binding region ATPase domain protein - - - 0.0000000000435 76.0
HKD1_k127_7158431_58 Recombinase zinc beta ribbon domain - - - 0.000000004486 61.0
HKD1_k127_7158431_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 533.0
HKD1_k127_7158431_7 Sodium/calcium exchanger protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 504.0
HKD1_k127_7158431_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 490.0
HKD1_k127_7158431_9 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 492.0
HKD1_k127_7208239_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.232e-283 886.0
HKD1_k127_7208239_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 604.0
HKD1_k127_7208239_10 ABC transporter ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 338.0
HKD1_k127_7208239_11 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 299.0
HKD1_k127_7208239_12 Trypsin K04691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004234 288.0
HKD1_k127_7208239_13 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001063 274.0
HKD1_k127_7208239_14 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000006296 247.0
HKD1_k127_7208239_15 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000001403 215.0
HKD1_k127_7208239_16 Stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000003648 182.0
HKD1_k127_7208239_17 TraB family K09973 - - 0.00000000000000000000000000000000000000000000006635 189.0
HKD1_k127_7208239_18 peptidase S16, lon K07157 - - 0.00000000000000000000000000000000000005652 162.0
HKD1_k127_7208239_19 COG1544 Ribosome-associated protein Y (PSrp-1) K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000001777 140.0
HKD1_k127_7208239_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 602.0
HKD1_k127_7208239_20 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000005288 108.0
HKD1_k127_7208239_21 Belongs to the BolA IbaG family - - - 0.00000000000000000005836 94.0
HKD1_k127_7208239_22 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.00000000000000002618 90.0
HKD1_k127_7208239_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 536.0
HKD1_k127_7208239_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 526.0
HKD1_k127_7208239_5 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 500.0
HKD1_k127_7208239_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 501.0
HKD1_k127_7208239_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 428.0
HKD1_k127_7208239_8 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 387.0
HKD1_k127_7208239_9 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 357.0
HKD1_k127_7273122_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.022e-213 674.0
HKD1_k127_7273122_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.251e-200 639.0
HKD1_k127_7273122_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 319.0
HKD1_k127_7273122_11 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000254 304.0
HKD1_k127_7273122_12 cell wall glycoprotein biosynthetic process K00344,K01809,K01840,K03431,K04035,K15778,K16881 GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,1.6.5.5,2.7.7.13,5.3.1.8,5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001372 275.0
HKD1_k127_7273122_13 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000005579 259.0
HKD1_k127_7273122_14 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004268 259.0
HKD1_k127_7273122_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001797 238.0
HKD1_k127_7273122_16 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000004071 238.0
HKD1_k127_7273122_17 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002007 253.0
HKD1_k127_7273122_18 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000006098 239.0
HKD1_k127_7273122_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000007535 224.0
HKD1_k127_7273122_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 564.0
HKD1_k127_7273122_20 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000007245 218.0
HKD1_k127_7273122_21 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000008147 229.0
HKD1_k127_7273122_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000003424 199.0
HKD1_k127_7273122_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000005453 200.0
HKD1_k127_7273122_24 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000001796 193.0
HKD1_k127_7273122_25 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000001905 193.0
HKD1_k127_7273122_26 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000003042 152.0
HKD1_k127_7273122_27 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.00000000000000000000000000001585 128.0
HKD1_k127_7273122_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000002576 103.0
HKD1_k127_7273122_29 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000002992 85.0
HKD1_k127_7273122_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 566.0
HKD1_k127_7273122_31 Belongs to the UPF0250 family K09158 - - 0.0000004221 63.0
HKD1_k127_7273122_32 belongs to the nudix hydrolase family K03574 - 3.6.1.55 0.0000005238 58.0
HKD1_k127_7273122_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 500.0
HKD1_k127_7273122_5 PCRF K02835 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 482.0
HKD1_k127_7273122_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 468.0
HKD1_k127_7273122_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 424.0
HKD1_k127_7273122_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 407.0
HKD1_k127_7273122_9 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 351.0
HKD1_k127_7283354_0 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 604.0
HKD1_k127_7283354_1 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 526.0
HKD1_k127_7283354_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000001663 199.0
HKD1_k127_7283354_11 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000002345 188.0
HKD1_k127_7283354_12 LysR substrate binding domain K05817 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000006041 192.0
HKD1_k127_7283354_13 Phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000003767 186.0
HKD1_k127_7283354_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000007131 166.0
HKD1_k127_7283354_15 - - - - 0.00000000000000000000000007456 121.0
HKD1_k127_7283354_17 Major Facilitator K02575 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0019222,GO:0031323,GO:0036293,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0062012,GO:0065007,GO:0070482,GO:0090352,GO:1903314 - 0.000000000000000001324 100.0
HKD1_k127_7283354_18 decarboxylase K01607 - 4.1.1.44 0.0000000000000004967 86.0
HKD1_k127_7283354_19 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000002045 76.0
HKD1_k127_7283354_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 463.0
HKD1_k127_7283354_20 - - - - 0.00000001187 58.0
HKD1_k127_7283354_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 380.0
HKD1_k127_7283354_4 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 358.0
HKD1_k127_7283354_5 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 347.0
HKD1_k127_7283354_6 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 360.0
HKD1_k127_7283354_7 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004617 277.0
HKD1_k127_7283354_8 ATP-binding protein K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000004706 246.0
HKD1_k127_7283354_9 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000002645 218.0
HKD1_k127_7294137_0 COG4993 Glucose dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 614.0
HKD1_k127_7294137_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 520.0
HKD1_k127_7294137_2 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 494.0
HKD1_k127_7294137_3 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 390.0
HKD1_k127_7294137_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 378.0
HKD1_k127_7294137_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003236 260.0
HKD1_k127_7294137_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000007312 188.0
HKD1_k127_7294137_7 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000001513 163.0
HKD1_k127_7294137_8 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000006801 135.0
HKD1_k127_7294137_9 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00007049 53.0
HKD1_k127_7359649_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1209.0
HKD1_k127_7359649_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 6.032e-239 749.0
HKD1_k127_7359649_10 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000009979 268.0
HKD1_k127_7359649_11 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004572 263.0
HKD1_k127_7359649_12 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000001982 241.0
HKD1_k127_7359649_13 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
HKD1_k127_7359649_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000004073 233.0
HKD1_k127_7359649_15 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000005181 198.0
HKD1_k127_7359649_16 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000004153 193.0
HKD1_k127_7359649_17 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000002596 171.0
HKD1_k127_7359649_18 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000003686 160.0
HKD1_k127_7359649_19 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000001423 168.0
HKD1_k127_7359649_2 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 9.792e-233 741.0
HKD1_k127_7359649_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000001913 150.0
HKD1_k127_7359649_21 COG2927 DNA polymerase III, chi subunit K02339 GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 0.000000000000000000000000000000000217 139.0
HKD1_k127_7359649_22 protein conserved in bacteria K09938 - - 0.00000000000000000000000002073 121.0
HKD1_k127_7359649_23 Protein of unknown function (DUF3108) - - - 0.000000000000000000000001012 113.0
HKD1_k127_7359649_24 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.0000000000000004942 85.0
HKD1_k127_7359649_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 556.0
HKD1_k127_7359649_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 475.0
HKD1_k127_7359649_5 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 432.0
HKD1_k127_7359649_6 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 435.0
HKD1_k127_7359649_7 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 398.0
HKD1_k127_7359649_8 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 372.0
HKD1_k127_7359649_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
HKD1_k127_7408711_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1442.0
HKD1_k127_7408711_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 584.0
HKD1_k127_7408711_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000003861 132.0
HKD1_k127_7408711_11 Protein of unknown function (DUF1244) K09948 - - 0.00000000000000000000000000000001927 133.0
HKD1_k127_7408711_12 belongs to the Fur family K09826 - - 0.0000000000000000000000000007069 119.0
HKD1_k127_7408711_13 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000000000000000000005719 110.0
HKD1_k127_7408711_14 Type II transport protein GspH K08084 - - 0.000000000000000000008461 99.0
HKD1_k127_7408711_15 - - - - 0.00000000000000000004359 101.0
HKD1_k127_7408711_16 - - - - 0.0000000000000000002799 99.0
HKD1_k127_7408711_17 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000008009 87.0
HKD1_k127_7408711_18 COG4967 Tfp pilus assembly protein PilV - - - 0.000000000001984 80.0
HKD1_k127_7408711_19 Type IV Pilus-assembly protein W K02672 - - 0.00000000000437 79.0
HKD1_k127_7408711_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 517.0
HKD1_k127_7408711_20 Type II transport protein GspH K08084 - - 0.0000001055 62.0
HKD1_k127_7408711_21 Pilus assembly protein PilX K02673 - - 0.00007566 55.0
HKD1_k127_7408711_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 473.0
HKD1_k127_7408711_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 434.0
HKD1_k127_7408711_5 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 389.0
HKD1_k127_7408711_6 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 346.0
HKD1_k127_7408711_7 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002093 274.0
HKD1_k127_7408711_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000004668 179.0
HKD1_k127_7408711_9 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000005809 132.0
HKD1_k127_7467540_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 4.593e-289 936.0
HKD1_k127_7467540_1 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 297.0
HKD1_k127_7467540_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001401 239.0
HKD1_k127_7480788_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.742e-278 864.0
HKD1_k127_7480788_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.213e-254 803.0
HKD1_k127_7480788_10 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 349.0
HKD1_k127_7480788_11 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 336.0
HKD1_k127_7480788_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 320.0
HKD1_k127_7480788_13 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 314.0
HKD1_k127_7480788_14 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
HKD1_k127_7480788_15 stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005173 230.0
HKD1_k127_7480788_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000001026 231.0
HKD1_k127_7480788_17 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000003215 218.0
HKD1_k127_7480788_18 Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000005983 213.0
HKD1_k127_7480788_19 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000003691 212.0
HKD1_k127_7480788_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.34e-221 709.0
HKD1_k127_7480788_20 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000003071 198.0
HKD1_k127_7480788_21 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000002416 176.0
HKD1_k127_7480788_22 COG3175 Cytochrome oxidase assembly factor K02258 - - 0.000000000000000000000000000000000000000000000003893 180.0
HKD1_k127_7480788_23 PFAM Fimbrial assembly K02663 - - 0.00000000000000000000000000000000000000000003484 168.0
HKD1_k127_7480788_24 pilus assembly protein pilp K02665 - - 0.0000000000000000000000000000000000000000001221 166.0
HKD1_k127_7480788_25 mRNA catabolic process - - - 0.000000000000000000000000000000004547 138.0
HKD1_k127_7480788_26 Competence protein - - - 0.0000000000000000000000000000000311 134.0
HKD1_k127_7480788_27 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000000144 126.0
HKD1_k127_7480788_28 SURF1-like protein K14998 - - 0.000000000000000000000000000008554 128.0
HKD1_k127_7480788_29 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000197 106.0
HKD1_k127_7480788_3 COG5009 Membrane carboxypeptidase penicillin-binding protein K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 2.08e-206 670.0
HKD1_k127_7480788_30 Protein of unknown function (DUF2909) - - - 0.0002447 49.0
HKD1_k127_7480788_31 signal sequence binding - - - 0.0004867 52.0
HKD1_k127_7480788_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 603.0
HKD1_k127_7480788_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 471.0
HKD1_k127_7480788_6 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 472.0
HKD1_k127_7480788_7 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 389.0
HKD1_k127_7480788_8 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 380.0
HKD1_k127_7480788_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 360.0
HKD1_k127_7486189_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.022e-226 711.0
HKD1_k127_7486189_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 561.0
HKD1_k127_7486189_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003921 284.0
HKD1_k127_7486189_3 SnoaL-like domain - - - 0.00000000000000000000000001941 124.0
HKD1_k127_7486189_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000001672 61.0
HKD1_k127_7623867_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K21133 - - 0.0 1066.0
HKD1_k127_7623867_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 5.609e-240 746.0
HKD1_k127_7623867_10 3-Demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003473 225.0
HKD1_k127_7623867_11 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000003546 171.0
HKD1_k127_7623867_12 COG3547 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000004249 125.0
HKD1_k127_7623867_13 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01077 - 3.1.3.1 0.0000000000000000000000003114 122.0
HKD1_k127_7623867_14 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000002826 103.0
HKD1_k127_7623867_15 - - - - 0.000000000006631 68.0
HKD1_k127_7623867_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 9.199e-201 632.0
HKD1_k127_7623867_3 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 575.0
HKD1_k127_7623867_4 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 426.0
HKD1_k127_7623867_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 406.0
HKD1_k127_7623867_6 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 376.0
HKD1_k127_7623867_7 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001057 262.0
HKD1_k127_7623867_8 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001221 262.0
HKD1_k127_7623867_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000002715 238.0
HKD1_k127_7629420_0 Sugar (and other) transporter - - - 3.866e-211 664.0
HKD1_k127_7629420_1 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 443.0
HKD1_k127_7629420_2 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 419.0
HKD1_k127_7629420_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 378.0
HKD1_k127_7629420_4 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 379.0
HKD1_k127_7629420_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000004426 194.0
HKD1_k127_7629420_6 LysE type translocator - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000143 166.0
HKD1_k127_7629420_7 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.0000000000000000000000000009092 123.0
HKD1_k127_7629420_8 Type III secretion system lipoprotein chaperone (YscW) - - - 0.00000000000000000000000002153 119.0
HKD1_k127_7629420_9 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000001252 110.0
HKD1_k127_7664735_0 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 366.0
HKD1_k127_7664735_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 375.0
HKD1_k127_7664735_2 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 319.0
HKD1_k127_7664735_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000003995 117.0
HKD1_k127_7664735_4 SnoaL-like domain - - - 0.000000000000000000000000006336 123.0
HKD1_k127_7664735_5 SnoaL-like domain - - - 0.00000000001587 76.0
HKD1_k127_7664735_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000008849 68.0
HKD1_k127_7798361_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 1.614e-233 747.0
HKD1_k127_7798361_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 512.0
HKD1_k127_7798361_2 Enoyl-CoA hydratase/isomerase K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 331.0
HKD1_k127_7798361_3 Ethyl tert-butyl ether degradation - - - 0.0000000000000000000000000000000000000003244 156.0
HKD1_k127_7811399_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1284.0
HKD1_k127_7811399_1 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 347.0
HKD1_k127_7811399_2 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 325.0
HKD1_k127_7811399_3 XRE family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 286.0
HKD1_k127_7811399_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000522 264.0
HKD1_k127_7811399_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000001215 217.0
HKD1_k127_7811399_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000006932 169.0
HKD1_k127_7811399_7 Protein of unknown function (DUF3240) - - - 0.000000000000000008997 87.0
HKD1_k127_7820767_0 Dehydrogenase K00117 - 1.1.5.2 1.838e-265 830.0
HKD1_k127_7820767_1 I - Lipid transport and metabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 485.0
HKD1_k127_7820767_2 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000004844 162.0
HKD1_k127_7988497_0 Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 592.0
HKD1_k127_7988497_1 protein-glutamate methylesterase K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 425.0
HKD1_k127_7988497_10 Alpha beta hydrolase fold-3 domain protein - - - 0.00000000000000000000000000001075 123.0
HKD1_k127_7988497_11 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000002961 126.0
HKD1_k127_7988497_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000008616 117.0
HKD1_k127_7988497_13 Dehydrogenase K00117 - 1.1.5.2 0.0000000000000000000000432 104.0
HKD1_k127_7988497_14 - - - - 0.000000000004316 78.0
HKD1_k127_7988497_15 - - - - 0.000001373 57.0
HKD1_k127_7988497_16 Glyoxalase-like domain - - - 0.0003742 52.0
HKD1_k127_7988497_2 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 385.0
HKD1_k127_7988497_3 receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 382.0
HKD1_k127_7988497_4 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 345.0
HKD1_k127_7988497_5 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 336.0
HKD1_k127_7988497_6 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000001793 235.0
HKD1_k127_7988497_7 Histidine kinase K01120,K07315 - 3.1.3.3,3.1.4.17 0.00000000000000000000000000000000000000000000003035 191.0
HKD1_k127_7988497_8 NUDIX domain - - - 0.000000000000000000000000000000000000000000001676 175.0
HKD1_k127_7988497_9 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000006386 126.0
HKD1_k127_90062_0 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 7.732e-251 789.0
HKD1_k127_90062_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 597.0
HKD1_k127_90062_10 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 428.0
HKD1_k127_90062_11 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 399.0
HKD1_k127_90062_12 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 325.0
HKD1_k127_90062_13 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 319.0
HKD1_k127_90062_14 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 316.0
HKD1_k127_90062_15 polyphosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 302.0
HKD1_k127_90062_16 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001162 287.0
HKD1_k127_90062_17 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 266.0
HKD1_k127_90062_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003717 256.0
HKD1_k127_90062_19 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000525 246.0
HKD1_k127_90062_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 562.0
HKD1_k127_90062_20 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005088 240.0
HKD1_k127_90062_21 TIGRFAM methyltransferase FkbM family - - - 0.000000000000000000000000000000000000000000000601 175.0
HKD1_k127_90062_22 Hydrolase - - - 0.0000000000000000000000000000000000003401 156.0
HKD1_k127_90062_23 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000001806 139.0
HKD1_k127_90062_24 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000002966 119.0
HKD1_k127_90062_25 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000002466 61.0
HKD1_k127_90062_26 FeoA K04758 - - 0.00000000773 60.0
HKD1_k127_90062_27 - - - - 0.0007228 51.0
HKD1_k127_90062_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 565.0
HKD1_k127_90062_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 476.0
HKD1_k127_90062_5 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 492.0
HKD1_k127_90062_6 Asparagine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 462.0
HKD1_k127_90062_7 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 452.0
HKD1_k127_90062_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 449.0
HKD1_k127_90062_9 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 445.0
HKD1_k127_90067_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1261.0
HKD1_k127_90067_1 COG4993 Glucose dehydrogenase - - - 5.396e-212 675.0
HKD1_k127_90067_10 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 284.0
HKD1_k127_90067_11 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000094 294.0
HKD1_k127_90067_12 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005471 272.0
HKD1_k127_90067_13 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003271 259.0
HKD1_k127_90067_14 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001569 240.0
HKD1_k127_90067_15 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000005373 232.0
HKD1_k127_90067_16 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003796 243.0
HKD1_k127_90067_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000001787 229.0
HKD1_k127_90067_18 MerR, DNA binding K13639 - - 0.0000000000000000000000000000000000000000000000000000004662 211.0
HKD1_k127_90067_19 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000002358 203.0
HKD1_k127_90067_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 9.267e-198 624.0
HKD1_k127_90067_20 PFAM branched-chain amino acid transport - - - 0.00000000000000000000000000000000000001955 146.0
HKD1_k127_90067_21 retrograde transport, endosome to plasma membrane K21440 - - 0.0000000000000000000000000000005816 141.0
HKD1_k127_90067_22 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000008773 125.0
HKD1_k127_90067_23 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 - - 0.00000000000000000000000008284 119.0
HKD1_k127_90067_24 - - - - 0.00000000000000000000000466 105.0
HKD1_k127_90067_25 Protein of unknown function (DUF2892) - - - 0.000000000000000000000007601 104.0
HKD1_k127_90067_26 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000003835 107.0
HKD1_k127_90067_27 Putative peptidoglycan binding domain - - - 0.0001219 48.0
HKD1_k127_90067_3 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 552.0
HKD1_k127_90067_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 468.0
HKD1_k127_90067_5 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 444.0
HKD1_k127_90067_6 FAD-NAD(P)-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 443.0
HKD1_k127_90067_7 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 350.0
HKD1_k127_90067_8 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 316.0
HKD1_k127_90067_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 302.0
HKD1_k127_97954_0 efflux pump K18138,K18322 - - 0.0 1385.0
HKD1_k127_97954_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1245.0
HKD1_k127_97954_10 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 500.0
HKD1_k127_97954_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 494.0
HKD1_k127_97954_12 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 466.0
HKD1_k127_97954_13 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 445.0
HKD1_k127_97954_14 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 459.0
HKD1_k127_97954_15 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 451.0
HKD1_k127_97954_16 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 433.0
HKD1_k127_97954_17 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 433.0
HKD1_k127_97954_18 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 427.0
HKD1_k127_97954_19 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 407.0
HKD1_k127_97954_2 negative regulation of hippo signaling - - - 6.792e-232 750.0
HKD1_k127_97954_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 408.0
HKD1_k127_97954_21 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 401.0
HKD1_k127_97954_22 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 389.0
HKD1_k127_97954_23 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 389.0
HKD1_k127_97954_24 FAD binding domain K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 395.0
HKD1_k127_97954_25 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 407.0
HKD1_k127_97954_26 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 383.0
HKD1_k127_97954_27 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 349.0
HKD1_k127_97954_28 SurA N-terminal domain K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 353.0
HKD1_k127_97954_29 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 366.0
HKD1_k127_97954_3 Protein of unknown function, DUF255 K06888 - - 5.319e-227 723.0
HKD1_k127_97954_30 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 323.0
HKD1_k127_97954_31 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 344.0
HKD1_k127_97954_32 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 323.0
HKD1_k127_97954_33 Type II secretory pathway component ExeA K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 316.0
HKD1_k127_97954_34 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 306.0
HKD1_k127_97954_35 PFAM Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 300.0
HKD1_k127_97954_36 Transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
HKD1_k127_97954_37 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 294.0
HKD1_k127_97954_38 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
HKD1_k127_97954_39 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001283 277.0
HKD1_k127_97954_4 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 5.002e-197 625.0
HKD1_k127_97954_40 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009457 285.0
HKD1_k127_97954_41 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000159 274.0
HKD1_k127_97954_42 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001085 266.0
HKD1_k127_97954_43 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002264 274.0
HKD1_k127_97954_44 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000003373 278.0
HKD1_k127_97954_45 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000001177 247.0
HKD1_k127_97954_46 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001858 269.0
HKD1_k127_97954_47 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000001773 248.0
HKD1_k127_97954_48 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000284 249.0
HKD1_k127_97954_49 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001065 236.0
HKD1_k127_97954_5 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 616.0
HKD1_k127_97954_50 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000001528 237.0
HKD1_k127_97954_51 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000001972 243.0
HKD1_k127_97954_52 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
HKD1_k127_97954_53 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000001101 227.0
HKD1_k127_97954_54 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000002582 224.0
HKD1_k127_97954_55 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000001011 216.0
HKD1_k127_97954_56 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000002811 204.0
HKD1_k127_97954_57 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005225 200.0
HKD1_k127_97954_58 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.000000000000000000000000000000000000000000000000000000005575 208.0
HKD1_k127_97954_59 - - - - 0.00000000000000000000000000000000000000000000000000002986 194.0
HKD1_k127_97954_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 601.0
HKD1_k127_97954_60 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000003996 194.0
HKD1_k127_97954_61 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000001925 192.0
HKD1_k127_97954_62 TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000002329 184.0
HKD1_k127_97954_63 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000005372 169.0
HKD1_k127_97954_64 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000442 168.0
HKD1_k127_97954_65 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000199 159.0
HKD1_k127_97954_66 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000006752 165.0
HKD1_k127_97954_67 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000001141 150.0
HKD1_k127_97954_68 transcriptional - - - 0.0000000000000000000000000000000001305 138.0
HKD1_k127_97954_69 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.000000000000000000000000000000001553 135.0
HKD1_k127_97954_7 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 556.0
HKD1_k127_97954_70 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000002627 128.0
HKD1_k127_97954_71 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000007956 111.0
HKD1_k127_97954_72 - - - - 0.0000000000000000000000001702 111.0
HKD1_k127_97954_73 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000001582 102.0
HKD1_k127_97954_74 Protein of unknown function, DUF255 K01829 - 5.3.4.1 0.00000000000000000000877 108.0
HKD1_k127_97954_75 Belongs to the UPF0149 family K09895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000007928 98.0
HKD1_k127_97954_76 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000003862 89.0
HKD1_k127_97954_77 Trm112p-like protein - - - 0.00000000000000004444 89.0
HKD1_k127_97954_78 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000008204 83.0
HKD1_k127_97954_79 COG0515 Serine threonine protein kinase K08884,K11912 - 2.7.11.1 0.000000000000009713 76.0
HKD1_k127_97954_8 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 544.0
HKD1_k127_97954_80 TIGRFAM TIGR02449 family protein K09892 - - 0.00000000008097 65.0
HKD1_k127_97954_81 salt-induced outer membrane protein K07283 - - 0.0000000008683 69.0
HKD1_k127_97954_82 WD-40 repeat-containing protein - - - 0.00003431 57.0
HKD1_k127_97954_9 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 522.0