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Overview

ID MAG01766
Name HKD1_bin.86
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus DAHUXD01
Species
Assembly information
Completeness (%) 65.37
Contamination (%) 0.01
GC content (%) 71.0
N50 (bp) 29,873
Genome size (bp) 2,973,286

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2455

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1041644_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.534e-269 854.0
HKD1_k127_1041644_1 Succinyl-CoA ligase like flavodoxin domain - - - 1.26e-265 849.0
HKD1_k127_1041644_10 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 384.0
HKD1_k127_1041644_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 381.0
HKD1_k127_1041644_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 371.0
HKD1_k127_1041644_13 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 362.0
HKD1_k127_1041644_14 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 356.0
HKD1_k127_1041644_15 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 377.0
HKD1_k127_1041644_16 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HKD1_k127_1041644_17 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 353.0
HKD1_k127_1041644_18 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 316.0
HKD1_k127_1041644_19 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 310.0
HKD1_k127_1041644_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.5e-198 648.0
HKD1_k127_1041644_20 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001153 286.0
HKD1_k127_1041644_21 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003749 292.0
HKD1_k127_1041644_22 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004728 295.0
HKD1_k127_1041644_23 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001126 289.0
HKD1_k127_1041644_24 Pfam ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004539 282.0
HKD1_k127_1041644_25 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002148 266.0
HKD1_k127_1041644_26 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001625 271.0
HKD1_k127_1041644_27 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000002823 254.0
HKD1_k127_1041644_28 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000002364 248.0
HKD1_k127_1041644_29 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000002081 236.0
HKD1_k127_1041644_3 Erythromycin esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 573.0
HKD1_k127_1041644_30 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000007215 229.0
HKD1_k127_1041644_31 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000002301 226.0
HKD1_k127_1041644_32 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000005412 214.0
HKD1_k127_1041644_33 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000005039 195.0
HKD1_k127_1041644_34 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000000000009757 154.0
HKD1_k127_1041644_35 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000001021 162.0
HKD1_k127_1041644_36 antibiotic catabolic process - - - 0.000000000000000000000000000000000000001611 169.0
HKD1_k127_1041644_37 - - - - 0.0000000000000000000000000000000000001312 157.0
HKD1_k127_1041644_38 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000006909 156.0
HKD1_k127_1041644_39 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000003156 155.0
HKD1_k127_1041644_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 526.0
HKD1_k127_1041644_40 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000002434 130.0
HKD1_k127_1041644_41 Yqey-like protein K09117 - - 0.0000000000000000000000000000004859 126.0
HKD1_k127_1041644_42 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000003157 135.0
HKD1_k127_1041644_43 4Fe-4S dicluster domain - - - 0.0000000000000000000000000003637 117.0
HKD1_k127_1041644_44 Reverse transcriptase-like K03469,K06864,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000001068 121.0
HKD1_k127_1041644_45 PFAM CBS domain containing protein K07168 - - 0.0000000000000000000000005772 117.0
HKD1_k127_1041644_46 CYTH domain K01768,K05873 - 4.6.1.1 0.000000000000000000000001292 116.0
HKD1_k127_1041644_47 Pas domain - - - 0.000000000000000000000057 107.0
HKD1_k127_1041644_48 Universal stress protein - - - 0.000000000000000000001289 100.0
HKD1_k127_1041644_49 Pas domain - - - 0.00000000000000000003058 106.0
HKD1_k127_1041644_5 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 488.0
HKD1_k127_1041644_50 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000004955 95.0
HKD1_k127_1041644_51 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000005391 94.0
HKD1_k127_1041644_52 DivIVA protein K04074 - - 0.000000000000000002731 95.0
HKD1_k127_1041644_53 Universal stress protein - - - 0.000000000000000002955 91.0
HKD1_k127_1041644_54 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002013 90.0
HKD1_k127_1041644_55 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000005148 91.0
HKD1_k127_1041644_56 Universal stress protein - - - 0.0000000000000005327 86.0
HKD1_k127_1041644_57 Helix-hairpin-helix motif K02237 - - 0.000000000000005657 81.0
HKD1_k127_1041644_58 C4-type zinc ribbon domain K07164 - - 0.000000000003723 76.0
HKD1_k127_1041644_59 Tyrosine phosphatase family - - - 0.0000000001933 72.0
HKD1_k127_1041644_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 451.0
HKD1_k127_1041644_60 DNA-templated transcription, termination K02600,K02945 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000008817 66.0
HKD1_k127_1041644_61 Family of unknown function (DUF5335) - - - 0.0000004912 59.0
HKD1_k127_1041644_62 TIGRFAM DNA binding domain protein, excisionase family - - - 0.000001752 59.0
HKD1_k127_1041644_63 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000004726 55.0
HKD1_k127_1041644_64 ABC transporter transmembrane region K06147 - - 0.00008356 55.0
HKD1_k127_1041644_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 454.0
HKD1_k127_1041644_8 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 429.0
HKD1_k127_1041644_9 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 405.0
HKD1_k127_1044659_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 526.0
HKD1_k127_1044659_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 397.0
HKD1_k127_1044659_2 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 404.0
HKD1_k127_1044659_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000008379 168.0
HKD1_k127_1044659_4 Pyruvate phosphate dikinase - - - 0.00002307 56.0
HKD1_k127_1065663_0 Malate synthase - - - 1.317e-224 707.0
HKD1_k127_1065663_1 isocitrate lyase activity K01637 GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700 4.1.3.1 3.3e-210 682.0
HKD1_k127_1065663_10 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.00000000000000000000000000000000000000000000000000000000000001794 236.0
HKD1_k127_1065663_11 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000000000003757 158.0
HKD1_k127_1065663_12 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000004436 155.0
HKD1_k127_1065663_13 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000003095 156.0
HKD1_k127_1065663_14 Redoxin - - - 0.0000000000000003288 88.0
HKD1_k127_1065663_2 Extracellular solute-binding protein K02027 - - 1.733e-195 619.0
HKD1_k127_1065663_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 579.0
HKD1_k127_1065663_4 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 563.0
HKD1_k127_1065663_5 Pfam:DUF955 K07110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 540.0
HKD1_k127_1065663_6 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 422.0
HKD1_k127_1065663_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 398.0
HKD1_k127_1065663_8 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 382.0
HKD1_k127_1065663_9 Binding-protein-dependent transport system inner membrane component K02025,K10118,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 395.0
HKD1_k127_1118215_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1046.0
HKD1_k127_1118215_1 Pyruvate phosphate dikinase K01006 - 2.7.9.1 2.269e-316 999.0
HKD1_k127_1118215_10 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 532.0
HKD1_k127_1118215_11 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 458.0
HKD1_k127_1118215_12 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 459.0
HKD1_k127_1118215_13 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 457.0
HKD1_k127_1118215_14 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 401.0
HKD1_k127_1118215_15 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 402.0
HKD1_k127_1118215_16 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 372.0
HKD1_k127_1118215_17 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 370.0
HKD1_k127_1118215_18 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 367.0
HKD1_k127_1118215_19 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 358.0
HKD1_k127_1118215_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.258e-283 899.0
HKD1_k127_1118215_20 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 331.0
HKD1_k127_1118215_21 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 338.0
HKD1_k127_1118215_22 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 319.0
HKD1_k127_1118215_23 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 326.0
HKD1_k127_1118215_24 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 316.0
HKD1_k127_1118215_25 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 316.0
HKD1_k127_1118215_26 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009263 290.0
HKD1_k127_1118215_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009 276.0
HKD1_k127_1118215_28 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001378 255.0
HKD1_k127_1118215_29 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000001626 255.0
HKD1_k127_1118215_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 8.228e-251 787.0
HKD1_k127_1118215_30 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000027 258.0
HKD1_k127_1118215_31 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000003832 238.0
HKD1_k127_1118215_32 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000007782 221.0
HKD1_k127_1118215_33 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000003061 239.0
HKD1_k127_1118215_34 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000007395 204.0
HKD1_k127_1118215_35 - - - - 0.0000000000000000000000000000000000000000000000005253 186.0
HKD1_k127_1118215_36 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000002963 198.0
HKD1_k127_1118215_37 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000004024 179.0
HKD1_k127_1118215_38 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000006699 180.0
HKD1_k127_1118215_39 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000002142 173.0
HKD1_k127_1118215_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 6.967e-231 728.0
HKD1_k127_1118215_40 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000007355 157.0
HKD1_k127_1118215_41 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000009851 138.0
HKD1_k127_1118215_43 Mg(2 ) transporter K07507 - - 0.0000000000000000000000000000001609 139.0
HKD1_k127_1118215_44 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000000000002026 125.0
HKD1_k127_1118215_46 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000001113 117.0
HKD1_k127_1118215_47 - - - - 0.00000000000000000000000003486 121.0
HKD1_k127_1118215_48 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000006463 110.0
HKD1_k127_1118215_49 hydroperoxide reductase activity - - - 0.00000000000000004873 96.0
HKD1_k127_1118215_5 solute:proton antiporter activity K03455 - - 1.154e-215 683.0
HKD1_k127_1118215_51 Protein of unknown function (DUF1697) - - - 0.0000000000009318 70.0
HKD1_k127_1118215_52 - K01822 - 5.3.3.1 0.00000006011 64.0
HKD1_k127_1118215_53 - - - - 0.0000003499 59.0
HKD1_k127_1118215_6 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 7.071e-213 669.0
HKD1_k127_1118215_7 Peptidase dimerisation domain - - - 2.65e-203 658.0
HKD1_k127_1118215_8 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.287e-195 622.0
HKD1_k127_1118215_9 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 584.0
HKD1_k127_1126877_0 Large extracellular alpha-helical protein - - - 0.0 2023.0
HKD1_k127_1126877_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1092.0
HKD1_k127_1126877_10 - - - - 0.0000000000000000000000004557 114.0
HKD1_k127_1126877_11 Belongs to the UPF0312 family - - - 0.0000000000000000000000005532 120.0
HKD1_k127_1126877_12 Protein of unknown function (DUF1761) - - - 0.0000000000000007912 82.0
HKD1_k127_1126877_13 AMP binding - - - 0.0000000003721 72.0
HKD1_k127_1126877_2 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 574.0
HKD1_k127_1126877_3 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 351.0
HKD1_k127_1126877_4 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 363.0
HKD1_k127_1126877_5 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 351.0
HKD1_k127_1126877_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006408 280.0
HKD1_k127_1126877_7 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001523 280.0
HKD1_k127_1126877_8 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000001677 213.0
HKD1_k127_1126877_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000002287 149.0
HKD1_k127_1194737_0 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 361.0
HKD1_k127_1194737_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 349.0
HKD1_k127_1194737_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 298.0
HKD1_k127_1194737_3 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000002694 269.0
HKD1_k127_1194737_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000003468 213.0
HKD1_k127_1194737_5 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000008087 175.0
HKD1_k127_1194737_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000001683 136.0
HKD1_k127_1194737_7 Pfam Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000001069 126.0
HKD1_k127_1194737_8 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000003669 121.0
HKD1_k127_1328325_0 OPT oligopeptide transporter protein - - - 6.071e-303 945.0
HKD1_k127_1328325_1 Beta-lactamase - - - 8.934e-205 659.0
HKD1_k127_1328325_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000004318 232.0
HKD1_k127_1328325_11 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000001527 192.0
HKD1_k127_1328325_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000006201 184.0
HKD1_k127_1328325_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000002625 140.0
HKD1_k127_1328325_14 - - - - 0.000000000000000000000000004841 130.0
HKD1_k127_1328325_16 DoxX family K16937 - 1.8.5.2 0.0008459 49.0
HKD1_k127_1328325_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 571.0
HKD1_k127_1328325_3 RNB K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 488.0
HKD1_k127_1328325_4 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 458.0
HKD1_k127_1328325_5 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 384.0
HKD1_k127_1328325_6 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 319.0
HKD1_k127_1328325_7 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004097 308.0
HKD1_k127_1328325_8 PFAM alanine racemase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006872 293.0
HKD1_k127_1328325_9 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000001068 245.0
HKD1_k127_1385612_0 outer membrane efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003827 257.0
HKD1_k127_1385612_1 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000007166 178.0
HKD1_k127_1385612_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000001464 153.0
HKD1_k127_1385612_3 YjbR - - - 0.0000000000000000000004135 103.0
HKD1_k127_1385612_4 Transcriptional regulator PadR-like family - - - 0.00000000000000000805 91.0
HKD1_k127_1385612_5 Domain of unknown function (DUF4410) - - - 0.000000000006337 75.0
HKD1_k127_1385612_6 Aspartyl protease - - - 0.0000000002832 64.0
HKD1_k127_145940_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 475.0
HKD1_k127_145940_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001254 295.0
HKD1_k127_145940_10 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000005117 164.0
HKD1_k127_145940_11 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000000315 111.0
HKD1_k127_145940_12 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.000000000000000000000004699 117.0
HKD1_k127_145940_13 antisigma factor binding - - - 0.00000000000000000000006494 106.0
HKD1_k127_145940_14 Acetyltransferase (GNAT) domain - - - 0.0000000003184 71.0
HKD1_k127_145940_15 Tetratricopeptide repeat - - - 0.0001746 54.0
HKD1_k127_145940_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000891 252.0
HKD1_k127_145940_3 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000003703 230.0
HKD1_k127_145940_4 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000525 232.0
HKD1_k127_145940_5 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000002042 206.0
HKD1_k127_145940_6 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000002777 185.0
HKD1_k127_145940_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000001845 189.0
HKD1_k127_145940_8 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000476 177.0
HKD1_k127_145940_9 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000001995 165.0
HKD1_k127_1493950_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 476.0
HKD1_k127_1493950_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000006078 274.0
HKD1_k127_1493950_2 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000001888 196.0
HKD1_k127_1493950_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000007276 63.0
HKD1_k127_1580193_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 1.539e-221 716.0
HKD1_k127_1580193_1 Response regulator receiver - - - 1.289e-197 625.0
HKD1_k127_1580193_10 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 349.0
HKD1_k127_1580193_11 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 354.0
HKD1_k127_1580193_12 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003632 284.0
HKD1_k127_1580193_13 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000003747 231.0
HKD1_k127_1580193_14 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
HKD1_k127_1580193_15 surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000009222 240.0
HKD1_k127_1580193_16 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
HKD1_k127_1580193_17 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000004011 192.0
HKD1_k127_1580193_18 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000003951 216.0
HKD1_k127_1580193_19 DinB family - - - 0.000000000000000000000000000000000000000000000000002889 186.0
HKD1_k127_1580193_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 625.0
HKD1_k127_1580193_20 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000004668 195.0
HKD1_k127_1580193_21 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000614 160.0
HKD1_k127_1580193_22 Histidine kinase - - - 0.00000000000000000000000000000000000000006 175.0
HKD1_k127_1580193_23 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000001396 153.0
HKD1_k127_1580193_24 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000001253 133.0
HKD1_k127_1580193_25 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000005355 138.0
HKD1_k127_1580193_26 - - - - 0.00000000000000000000000001224 114.0
HKD1_k127_1580193_27 Regulatory protein, FmdB family - - - 0.00000000000000000002845 92.0
HKD1_k127_1580193_28 ThiS family K03636 - - 0.0000000000000002234 88.0
HKD1_k127_1580193_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 633.0
HKD1_k127_1580193_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 602.0
HKD1_k127_1580193_5 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 522.0
HKD1_k127_1580193_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 493.0
HKD1_k127_1580193_7 Y_Y_Y domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 512.0
HKD1_k127_1580193_8 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 483.0
HKD1_k127_1580193_9 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 484.0
HKD1_k127_165071_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 495.0
HKD1_k127_165071_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 462.0
HKD1_k127_165071_10 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000004577 203.0
HKD1_k127_165071_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000004227 169.0
HKD1_k127_165071_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000007388 168.0
HKD1_k127_165071_13 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000002428 139.0
HKD1_k127_165071_14 PFAM Peptidase M23 K21471 - - 0.000000000000000000000000000002587 141.0
HKD1_k127_165071_15 Thioesterase superfamily K10806 - - 0.00000000000000000000000000002591 136.0
HKD1_k127_165071_16 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000009587 126.0
HKD1_k127_165071_17 Protein of unknown function, DUF393 - - - 0.00000000000097 81.0
HKD1_k127_165071_18 - - - - 0.0000000005082 72.0
HKD1_k127_165071_19 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.0000001722 64.0
HKD1_k127_165071_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 424.0
HKD1_k127_165071_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 393.0
HKD1_k127_165071_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 387.0
HKD1_k127_165071_5 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 325.0
HKD1_k127_165071_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002926 271.0
HKD1_k127_165071_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000006219 263.0
HKD1_k127_165071_8 - - - - 0.000000000000000000000000000000000000000000000000000000185 217.0
HKD1_k127_165071_9 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000004374 218.0
HKD1_k127_1654988_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1232.0
HKD1_k127_1654988_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.427e-298 935.0
HKD1_k127_1654988_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 373.0
HKD1_k127_1654988_11 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 367.0
HKD1_k127_1654988_12 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 310.0
HKD1_k127_1654988_13 KR domain K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001037 284.0
HKD1_k127_1654988_14 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005082 285.0
HKD1_k127_1654988_15 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008391 263.0
HKD1_k127_1654988_16 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000006794 252.0
HKD1_k127_1654988_17 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000132 231.0
HKD1_k127_1654988_18 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000001415 241.0
HKD1_k127_1654988_19 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000006549 224.0
HKD1_k127_1654988_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 569.0
HKD1_k127_1654988_20 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000007911 227.0
HKD1_k127_1654988_21 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000001686 214.0
HKD1_k127_1654988_22 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000009347 188.0
HKD1_k127_1654988_23 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000115 194.0
HKD1_k127_1654988_24 Histidine kinase K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001357 196.0
HKD1_k127_1654988_25 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000001744 191.0
HKD1_k127_1654988_26 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000005377 172.0
HKD1_k127_1654988_27 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000006109 183.0
HKD1_k127_1654988_28 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000005207 156.0
HKD1_k127_1654988_29 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000005279 168.0
HKD1_k127_1654988_3 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 548.0
HKD1_k127_1654988_30 HemY domain protein - - - 0.00000000000000000000000000000000000008749 164.0
HKD1_k127_1654988_31 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000003498 153.0
HKD1_k127_1654988_32 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000009616 154.0
HKD1_k127_1654988_33 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000004116 143.0
HKD1_k127_1654988_34 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000495 126.0
HKD1_k127_1654988_35 PFAM RNA recognition motif - - - 0.000000000000000000000000001641 117.0
HKD1_k127_1654988_36 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000618 124.0
HKD1_k127_1654988_37 - - - - 0.0000000000000000004102 100.0
HKD1_k127_1654988_38 DinB superfamily - - - 0.000000000000000003538 91.0
HKD1_k127_1654988_39 Metallo-beta-lactamase superfamily K05555 - - 0.00000000000000004179 93.0
HKD1_k127_1654988_4 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 510.0
HKD1_k127_1654988_40 Tellurite resistance protein TerB - - - 0.00000000000000009386 93.0
HKD1_k127_1654988_41 Mo-molybdopterin cofactor metabolic process K03636,K03637,K03752,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12,4.6.1.17 0.00000000001655 67.0
HKD1_k127_1654988_42 Protein of unknown function (DUF2892) - - - 0.000000006253 60.0
HKD1_k127_1654988_43 AraC-like ligand binding domain - - - 0.00001405 51.0
HKD1_k127_1654988_5 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 421.0
HKD1_k127_1654988_6 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 417.0
HKD1_k127_1654988_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 409.0
HKD1_k127_1654988_8 Acts as a magnesium transporter K04767,K06213,K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 402.0
HKD1_k127_1654988_9 Pyridoxal-dependent decarboxylase conserved domain K00486,K01593 - 1.14.13.9,4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 392.0
HKD1_k127_174662_0 PFAM Amidase - - - 2.503e-266 832.0
HKD1_k127_174662_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 2.527e-233 751.0
HKD1_k127_174662_10 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 390.0
HKD1_k127_174662_11 NAD-dependent histone deacetylase activity (H3-K14 specific) K11407 - 3.5.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 340.0
HKD1_k127_174662_12 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 310.0
HKD1_k127_174662_13 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 301.0
HKD1_k127_174662_14 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001919 304.0
HKD1_k127_174662_15 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002789 267.0
HKD1_k127_174662_16 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001267 261.0
HKD1_k127_174662_17 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005451 263.0
HKD1_k127_174662_18 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000001161 217.0
HKD1_k127_174662_19 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000004468 228.0
HKD1_k127_174662_2 Prolyl oligopeptidase family - - - 4.166e-211 665.0
HKD1_k127_174662_20 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000009793 203.0
HKD1_k127_174662_21 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000002558 205.0
HKD1_k127_174662_22 - - - - 0.00000000000000000000000000000000000000000000000000002075 200.0
HKD1_k127_174662_23 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000000000000005813 184.0
HKD1_k127_174662_24 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000000000000004495 170.0
HKD1_k127_174662_25 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000001827 165.0
HKD1_k127_174662_26 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000004767 162.0
HKD1_k127_174662_27 4Fe-4S binding domain - - - 0.0000000000000000000000000000005669 128.0
HKD1_k127_174662_28 Thioredoxin-like - - - 0.0000000000000000000000001166 113.0
HKD1_k127_174662_29 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000001916 121.0
HKD1_k127_174662_3 Protein of unknown function, DUF255 K06888 - - 1.947e-197 636.0
HKD1_k127_174662_30 FAD dependent oxidoreductase - - - 0.00000000000005804 85.0
HKD1_k127_174662_31 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000000002638 77.0
HKD1_k127_174662_32 PBS lyase HEAT-like repeat - - - 0.000000001307 70.0
HKD1_k127_174662_33 - - - - 0.00000001946 62.0
HKD1_k127_174662_34 - - - - 0.000002408 53.0
HKD1_k127_174662_35 - - - - 0.00005705 54.0
HKD1_k127_174662_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0004295 47.0
HKD1_k127_174662_4 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 625.0
HKD1_k127_174662_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 556.0
HKD1_k127_174662_6 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 499.0
HKD1_k127_174662_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 435.0
HKD1_k127_174662_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 425.0
HKD1_k127_174662_9 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 401.0
HKD1_k127_17897_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 8.83e-283 909.0
HKD1_k127_17897_1 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 419.0
HKD1_k127_17897_10 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 315.0
HKD1_k127_17897_11 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 311.0
HKD1_k127_17897_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001006 281.0
HKD1_k127_17897_13 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000001659 271.0
HKD1_k127_17897_14 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006229 270.0
HKD1_k127_17897_15 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000002886 260.0
HKD1_k127_17897_16 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000001034 247.0
HKD1_k127_17897_17 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000001885 241.0
HKD1_k127_17897_18 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000005294 219.0
HKD1_k127_17897_19 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000003138 208.0
HKD1_k127_17897_2 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 392.0
HKD1_k127_17897_20 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000115 202.0
HKD1_k127_17897_21 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000005402 220.0
HKD1_k127_17897_22 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000003195 185.0
HKD1_k127_17897_23 - K07018 - - 0.000000000000000000000000000000000000000000004357 171.0
HKD1_k127_17897_24 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000001498 170.0
HKD1_k127_17897_25 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000009653 153.0
HKD1_k127_17897_26 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000001042 139.0
HKD1_k127_17897_27 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000004418 145.0
HKD1_k127_17897_28 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000007142 128.0
HKD1_k127_17897_29 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000001366 135.0
HKD1_k127_17897_3 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008713 354.0
HKD1_k127_17897_30 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000228 126.0
HKD1_k127_17897_31 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000001961 116.0
HKD1_k127_17897_32 Outer membrane lipoprotein - - - 0.00000000000000000000000007596 119.0
HKD1_k127_17897_33 EamA-like transporter family - - - 0.0000000000000000000000001703 123.0
HKD1_k127_17897_34 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000007528 106.0
HKD1_k127_17897_35 thiolester hydrolase activity K17362 - - 0.0000000000000000407 87.0
HKD1_k127_17897_36 TonB C terminal K03646,K03832 - - 0.00000000006456 72.0
HKD1_k127_17897_37 Ribosomal protein S20 K02968 - - 0.0000000001615 65.0
HKD1_k127_17897_38 outer membrane chaperone Skp (OmpH) K06142 - - 0.000000002694 66.0
HKD1_k127_17897_39 PFAM Transglutaminase-like - - - 0.000000003142 71.0
HKD1_k127_17897_4 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 342.0
HKD1_k127_17897_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 366.0
HKD1_k127_17897_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 344.0
HKD1_k127_17897_7 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 330.0
HKD1_k127_17897_8 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 333.0
HKD1_k127_17897_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 335.0
HKD1_k127_1829049_0 metallopeptidase activity K01179 - 3.2.1.4 1.957e-231 779.0
HKD1_k127_1829049_1 PFAM amidohydrolase - - - 7.664e-202 652.0
HKD1_k127_1829049_10 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000005715 241.0
HKD1_k127_1829049_11 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000001662 209.0
HKD1_k127_1829049_12 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000004253 198.0
HKD1_k127_1829049_13 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000000005372 194.0
HKD1_k127_1829049_14 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000000002002 179.0
HKD1_k127_1829049_15 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000000005054 160.0
HKD1_k127_1829049_16 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000004564 174.0
HKD1_k127_1829049_17 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000001332 170.0
HKD1_k127_1829049_18 SPTR Conserved repeat domain protein - - - 0.00000000000000000000000000000000000000313 171.0
HKD1_k127_1829049_19 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000003791 123.0
HKD1_k127_1829049_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 573.0
HKD1_k127_1829049_21 glyoxalase III activity - - - 0.0000000000000001576 85.0
HKD1_k127_1829049_23 domain, Protein K20276,K21449 - - 0.0000000000007638 81.0
HKD1_k127_1829049_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 569.0
HKD1_k127_1829049_4 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 552.0
HKD1_k127_1829049_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 435.0
HKD1_k127_1829049_6 Putative zinc-finger K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 344.0
HKD1_k127_1829049_7 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 272.0
HKD1_k127_1829049_8 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000515 252.0
HKD1_k127_1829049_9 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000005436 221.0
HKD1_k127_1839263_0 Belongs to the aldehyde dehydrogenase family K00128,K00138,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 605.0
HKD1_k127_1839263_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 578.0
HKD1_k127_1839263_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 549.0
HKD1_k127_1839263_3 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 361.0
HKD1_k127_1839263_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000006589 207.0
HKD1_k127_1839263_5 - - - - 0.00000000000000000000000008494 117.0
HKD1_k127_1839263_6 ThiS family K03154 - - 0.0000000000002608 81.0
HKD1_k127_1910266_0 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000003601 239.0
HKD1_k127_1910266_1 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000006921 194.0
HKD1_k127_2051221_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 419.0
HKD1_k127_2051221_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 325.0
HKD1_k127_2051221_10 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000009549 117.0
HKD1_k127_2051221_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000575 111.0
HKD1_k127_2051221_12 Could be involved in septation K06412 - - 0.00000000000000000000000138 117.0
HKD1_k127_2051221_13 Ribosomal protein S18 K02963 - - 0.000000000000000000000003853 111.0
HKD1_k127_2051221_14 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000003541 87.0
HKD1_k127_2051221_15 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000007874 68.0
HKD1_k127_2051221_16 Predicted membrane protein (DUF2232) - - - 0.00006864 54.0
HKD1_k127_2051221_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000001795 185.0
HKD1_k127_2051221_3 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000001792 190.0
HKD1_k127_2051221_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000796 165.0
HKD1_k127_2051221_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000001938 166.0
HKD1_k127_2051221_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000001723 153.0
HKD1_k127_2051221_7 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000001145 151.0
HKD1_k127_2051221_8 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000007834 143.0
HKD1_k127_2051221_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000501 138.0
HKD1_k127_2070682_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1088.0
HKD1_k127_2070682_1 Dehydrogenase E1 component K11381 - 1.2.4.4 3.5e-323 1000.0
HKD1_k127_2070682_10 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000007943 239.0
HKD1_k127_2070682_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000194 211.0
HKD1_k127_2070682_12 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000001726 195.0
HKD1_k127_2070682_13 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000002987 170.0
HKD1_k127_2070682_14 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000000000000000000000000000000007526 168.0
HKD1_k127_2070682_15 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000008066 152.0
HKD1_k127_2070682_16 - - - - 0.00000000000000000000000000000009252 138.0
HKD1_k127_2070682_17 PFAM response regulator receiver K07657 - - 0.000000000000000000000000007428 128.0
HKD1_k127_2070682_18 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000005505 115.0
HKD1_k127_2070682_19 Radical SAM superfamily - - - 0.000000000000000000003407 107.0
HKD1_k127_2070682_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 7.813e-316 981.0
HKD1_k127_2070682_20 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000001719 95.0
HKD1_k127_2070682_21 TIGRFAM DNA binding domain protein, excisionase family - - - 0.00000000135 66.0
HKD1_k127_2070682_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 3.508e-223 698.0
HKD1_k127_2070682_4 Cytochrome c - - - 5.924e-198 624.0
HKD1_k127_2070682_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 609.0
HKD1_k127_2070682_6 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 352.0
HKD1_k127_2070682_7 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003024 291.0
HKD1_k127_2070682_8 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005931 275.0
HKD1_k127_2070682_9 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000254 264.0
HKD1_k127_2078751_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 587.0
HKD1_k127_2078751_1 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 573.0
HKD1_k127_2078751_10 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000002896 213.0
HKD1_k127_2078751_11 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000002704 195.0
HKD1_k127_2078751_12 - - - - 0.0000000000000000000000000000000000000000000001966 183.0
HKD1_k127_2078751_13 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000003264 179.0
HKD1_k127_2078751_14 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000002239 143.0
HKD1_k127_2078751_15 Metallo-peptidase family M12 - - - 0.0000000000000000000000000001256 134.0
HKD1_k127_2078751_16 PFAM Outer membrane efflux protein - - - 0.000000000000001915 89.0
HKD1_k127_2078751_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000001004 83.0
HKD1_k127_2078751_18 PQQ enzyme repeat - - - 0.00000000005068 76.0
HKD1_k127_2078751_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 414.0
HKD1_k127_2078751_20 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000129 58.0
HKD1_k127_2078751_21 PFAM blue (type 1) copper domain protein - - - 0.00005533 55.0
HKD1_k127_2078751_3 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 391.0
HKD1_k127_2078751_4 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 394.0
HKD1_k127_2078751_5 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 361.0
HKD1_k127_2078751_6 Peptidase family S51 K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002347 271.0
HKD1_k127_2078751_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004811 267.0
HKD1_k127_2078751_8 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000008566 239.0
HKD1_k127_2078751_9 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000002796 207.0
HKD1_k127_210932_0 B12 binding domain K00548 - 2.1.1.13 0.0 1304.0
HKD1_k127_210932_1 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 635.0
HKD1_k127_210932_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 272.0
HKD1_k127_210932_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000228 243.0
HKD1_k127_210932_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
HKD1_k127_210932_13 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000001072 199.0
HKD1_k127_210932_14 sequence-specific DNA binding K03719 - - 0.000000000000000000000000000000000000000000000105 173.0
HKD1_k127_210932_15 DinB family - - - 0.00000000000000000000000000000000009725 145.0
HKD1_k127_210932_16 Alpha beta hydrolase - - - 0.000000000000000000000000001367 127.0
HKD1_k127_210932_17 helix_turn_helix, Lux Regulon - - - 0.00000000000000000002212 103.0
HKD1_k127_210932_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 452.0
HKD1_k127_210932_3 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 392.0
HKD1_k127_210932_4 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 349.0
HKD1_k127_210932_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 333.0
HKD1_k127_210932_6 4-hydroxy-tetrahydrodipicolinate reductase K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 301.0
HKD1_k127_210932_7 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002725 281.0
HKD1_k127_210932_8 TOBE domain K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000961 280.0
HKD1_k127_210932_9 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006566 288.0
HKD1_k127_2125156_0 Heat shock 70 kDa protein K04043 - - 5.64e-303 939.0
HKD1_k127_2125156_1 Flavin containing amine oxidoreductase - - - 8.541e-279 865.0
HKD1_k127_2125156_10 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000001756 242.0
HKD1_k127_2125156_11 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000005188 216.0
HKD1_k127_2125156_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000001817 196.0
HKD1_k127_2125156_13 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000008034 181.0
HKD1_k127_2125156_14 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000001405 166.0
HKD1_k127_2125156_15 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000006295 121.0
HKD1_k127_2125156_16 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000001684 106.0
HKD1_k127_2125156_17 oxidoreductase activity - - - 0.0000000000000009983 91.0
HKD1_k127_2125156_18 Domain of unknown function (DUF1844) - - - 0.000000000503 66.0
HKD1_k127_2125156_19 Domain of unknown function (DUF4388) - - - 0.0000001374 64.0
HKD1_k127_2125156_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.083e-209 665.0
HKD1_k127_2125156_20 chaperone-mediated protein folding - - - 0.00003587 57.0
HKD1_k127_2125156_21 CHAD - - - 0.00007119 53.0
HKD1_k127_2125156_22 Signal transduction protein - - - 0.0002534 53.0
HKD1_k127_2125156_23 protein N-acetylglucosaminyltransferase activity - - - 0.0008453 53.0
HKD1_k127_2125156_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 554.0
HKD1_k127_2125156_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 567.0
HKD1_k127_2125156_5 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 466.0
HKD1_k127_2125156_6 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 380.0
HKD1_k127_2125156_7 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 364.0
HKD1_k127_2125156_8 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 334.0
HKD1_k127_2125156_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000008189 249.0
HKD1_k127_2156815_0 B12 binding domain - - - 2.895e-223 702.0
HKD1_k127_2156815_1 IgA Peptidase M64 - - - 2.08e-206 670.0
HKD1_k127_2156815_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 497.0
HKD1_k127_2156815_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009729 249.0
HKD1_k127_2156815_4 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002797 256.0
HKD1_k127_2156815_5 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000005797 175.0
HKD1_k127_2156815_6 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000002593 124.0
HKD1_k127_2156815_7 - - - - 0.000000000000000007631 99.0
HKD1_k127_2179441_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 5.239e-240 767.0
HKD1_k127_2179441_1 Prolyl oligopeptidase family - - - 3.989e-195 630.0
HKD1_k127_2179441_10 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 332.0
HKD1_k127_2179441_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 317.0
HKD1_k127_2179441_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000262 265.0
HKD1_k127_2179441_13 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
HKD1_k127_2179441_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000007313 229.0
HKD1_k127_2179441_15 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000008993 251.0
HKD1_k127_2179441_16 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000004153 237.0
HKD1_k127_2179441_17 GTP cyclohydrolase 1 K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000001412 195.0
HKD1_k127_2179441_18 PFAM PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000008236 190.0
HKD1_k127_2179441_19 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000228 185.0
HKD1_k127_2179441_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 497.0
HKD1_k127_2179441_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000003193 156.0
HKD1_k127_2179441_21 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000005568 149.0
HKD1_k127_2179441_22 COGs COG0110 Acetyltransferase (isoleucine patch superfamily) K00633 - 2.3.1.18 0.0000000000000000000000000000000000002891 147.0
HKD1_k127_2179441_23 Protein of unknown function with PCYCGC motif - - - 0.0000000009344 66.0
HKD1_k127_2179441_24 Thioredoxin-like - - - 0.0000153 57.0
HKD1_k127_2179441_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 446.0
HKD1_k127_2179441_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 456.0
HKD1_k127_2179441_5 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 428.0
HKD1_k127_2179441_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 407.0
HKD1_k127_2179441_7 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 403.0
HKD1_k127_2179441_8 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 410.0
HKD1_k127_2179441_9 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 357.0
HKD1_k127_2191783_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 561.0
HKD1_k127_2191783_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 419.0
HKD1_k127_2191783_10 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000003737 87.0
HKD1_k127_2191783_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 430.0
HKD1_k127_2191783_3 Dihydroxyacetone kinase family K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 437.0
HKD1_k127_2191783_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000006018 195.0
HKD1_k127_2191783_5 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000003071 180.0
HKD1_k127_2191783_6 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000002865 179.0
HKD1_k127_2191783_7 lipase activity K15349 - - 0.00000000000000000000000000000000000000001161 171.0
HKD1_k127_2191783_8 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000006575 154.0
HKD1_k127_2191783_9 - - - - 0.00000000000000007292 83.0
HKD1_k127_2220349_0 MacB-like periplasmic core domain - - - 3.902e-275 869.0
HKD1_k127_2220349_1 Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 628.0
HKD1_k127_2220349_10 Cytochrome c - - - 0.000000000000000000000000000000000000000000009743 173.0
HKD1_k127_2220349_11 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000002715 179.0
HKD1_k127_2220349_12 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000102 151.0
HKD1_k127_2220349_15 alginic acid biosynthetic process K12287 - - 0.000000000000008715 89.0
HKD1_k127_2220349_19 domain, Protein K20276 - - 0.0003229 52.0
HKD1_k127_2220349_2 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 609.0
HKD1_k127_2220349_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 507.0
HKD1_k127_2220349_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 339.0
HKD1_k127_2220349_5 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000003365 246.0
HKD1_k127_2220349_6 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
HKD1_k127_2220349_7 Psort location CytoplasmicMembrane, score K09792 - - 0.00000000000000000000000000000000000000000000000002176 190.0
HKD1_k127_2220349_9 cytochrome C oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000002554 172.0
HKD1_k127_2258427_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 585.0
HKD1_k127_2258427_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 554.0
HKD1_k127_2258427_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006104 253.0
HKD1_k127_2258427_3 - - - - 0.00000000000000000000000000000000000000000000000000000001016 207.0
HKD1_k127_2258427_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000001764 153.0
HKD1_k127_2262504_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 8.235e-211 674.0
HKD1_k127_2262504_1 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 512.0
HKD1_k127_2262504_10 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 312.0
HKD1_k127_2262504_11 Cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 314.0
HKD1_k127_2262504_12 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000007715 257.0
HKD1_k127_2262504_13 Formyl transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000001361 220.0
HKD1_k127_2262504_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000007967 205.0
HKD1_k127_2262504_15 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000001093 190.0
HKD1_k127_2262504_16 Polysaccharide export protein K01991,K20988 - - 0.000000000000000000000000000000000000000000000000009321 204.0
HKD1_k127_2262504_17 transferase activity, transferring glycosyl groups K01784 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 5.1.3.2 0.00000000000000000000000000000000000000000000000005199 195.0
HKD1_k127_2262504_18 Pfam Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000095 202.0
HKD1_k127_2262504_19 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000497 185.0
HKD1_k127_2262504_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 447.0
HKD1_k127_2262504_20 PFAM Transcription termination factor nusG K05785 - - 0.0000000000000000000000003461 113.0
HKD1_k127_2262504_21 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.0000000000000000000000009235 123.0
HKD1_k127_2262504_22 Glycosyl transferase family 2 - - - 0.000000000000000000000004986 115.0
HKD1_k127_2262504_23 polysaccharide deacetylase - - - 0.000000000000000000003844 108.0
HKD1_k127_2262504_24 Glycosyl transferase 4-like domain - - - 0.00000000000000006018 96.0
HKD1_k127_2262504_25 O-antigen ligase like membrane protein - - - 0.0000000000000005557 93.0
HKD1_k127_2262504_26 O-Antigen ligase K02847 - - 0.00000001009 68.0
HKD1_k127_2262504_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 420.0
HKD1_k127_2262504_4 PFAM N-acetylneuraminic acid synthase K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 404.0
HKD1_k127_2262504_5 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 403.0
HKD1_k127_2262504_6 NAD-dependent epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 355.0
HKD1_k127_2262504_7 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 350.0
HKD1_k127_2262504_8 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 341.0
HKD1_k127_2262504_9 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 339.0
HKD1_k127_2339430_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 442.0
HKD1_k127_2339430_1 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 415.0
HKD1_k127_2339430_2 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 342.0
HKD1_k127_2339430_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005971 262.0
HKD1_k127_2339430_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000003831 224.0
HKD1_k127_2339430_5 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000001435 208.0
HKD1_k127_2339430_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000004547 193.0
HKD1_k127_2339430_7 Tetratricopeptide repeat - - - 0.00000000000000005834 91.0
HKD1_k127_2339430_8 lactoylglutathione lyase activity - - - 0.000000001943 65.0
HKD1_k127_2339430_9 - - - - 0.0000143 51.0
HKD1_k127_2359267_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 551.0
HKD1_k127_2359267_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 363.0
HKD1_k127_2359267_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000996 122.0
HKD1_k127_2359267_3 - - - - 0.000000000000000000000151 108.0
HKD1_k127_2359267_4 Protein of unknown function (DUF962) - - - 0.0000001228 61.0
HKD1_k127_2389955_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 564.0
HKD1_k127_2389955_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 508.0
HKD1_k127_2389955_10 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000009354 144.0
HKD1_k127_2389955_11 - - - - 0.000000000000000000008716 100.0
HKD1_k127_2389955_12 FR47-like protein K03789 - 2.3.1.128 0.000000000000000002649 96.0
HKD1_k127_2389955_14 - - - - 0.00000003014 66.0
HKD1_k127_2389955_15 Domain of unknown function DUF11 - - - 0.0005322 47.0
HKD1_k127_2389955_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 381.0
HKD1_k127_2389955_3 Glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 356.0
HKD1_k127_2389955_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000001342 255.0
HKD1_k127_2389955_5 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000007667 206.0
HKD1_k127_2389955_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000004936 179.0
HKD1_k127_2389955_8 regulation of ruffle assembly - - - 0.0000000000000000000000000000000000000002599 173.0
HKD1_k127_2389955_9 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000003382 145.0
HKD1_k127_2486737_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 602.0
HKD1_k127_2486737_1 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 330.0
HKD1_k127_2486737_2 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 297.0
HKD1_k127_2486737_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001536 257.0
HKD1_k127_2486737_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000004272 225.0
HKD1_k127_2486737_6 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.000003771 58.0
HKD1_k127_2494060_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000006989 211.0
HKD1_k127_2494060_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000002855 183.0
HKD1_k127_2494060_2 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000005791 168.0
HKD1_k127_2494060_3 arylsulfatase activity K01133 - 3.1.6.6 0.000000000000000000000000000000000000005188 163.0
HKD1_k127_2494060_4 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.000000000000000000000000000000002202 139.0
HKD1_k127_2496385_0 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 406.0
HKD1_k127_2496385_1 Domain of unknown function (DUF1972) K12996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
HKD1_k127_2496385_2 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000004937 251.0
HKD1_k127_2496385_3 domain protein - - - 0.00000000000000000000000000000000000000000000002771 175.0
HKD1_k127_2496385_4 Hfq protein - - - 0.00000000000000000000000000000115 125.0
HKD1_k127_2496385_5 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000009351 130.0
HKD1_k127_2496385_6 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000002814 121.0
HKD1_k127_260613_0 4Fe-4S single cluster domain K06937 - - 1.054e-248 782.0
HKD1_k127_260613_1 GTP-binding protein TypA K06207 - - 1.442e-204 654.0
HKD1_k127_260613_10 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000589 231.0
HKD1_k127_260613_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000007859 201.0
HKD1_k127_260613_12 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000003057 158.0
HKD1_k127_260613_13 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000003886 157.0
HKD1_k127_260613_14 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000008736 151.0
HKD1_k127_260613_15 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000001393 150.0
HKD1_k127_260613_16 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000305 139.0
HKD1_k127_260613_17 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000001894 126.0
HKD1_k127_260613_18 phosphotransferase related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.00000000000000000000000001037 127.0
HKD1_k127_260613_19 PFAM CBS domain containing protein - - - 0.000000000000000000000003594 108.0
HKD1_k127_260613_2 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 606.0
HKD1_k127_260613_20 Bacterial membrane protein YfhO - - - 0.000000000000000005686 99.0
HKD1_k127_260613_21 Translation initiation factor SUI1 K03113 - - 0.000000000000000009237 98.0
HKD1_k127_260613_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001075 70.0
HKD1_k127_260613_23 LysM domain - - - 0.000000000004779 76.0
HKD1_k127_260613_24 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000003227 66.0
HKD1_k127_260613_25 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0009014 46.0
HKD1_k127_260613_3 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 414.0
HKD1_k127_260613_4 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 308.0
HKD1_k127_260613_5 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006086 299.0
HKD1_k127_260613_6 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008721 291.0
HKD1_k127_260613_7 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000005241 273.0
HKD1_k127_260613_8 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001754 264.0
HKD1_k127_260613_9 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000001305 248.0
HKD1_k127_2617985_0 Sortilin, neurotensin receptor 3, - - - 0.0 1333.0
HKD1_k127_2617985_1 Dehydrogenase E1 component K11381 - 1.2.4.4 3.473e-289 905.0
HKD1_k127_2617985_10 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 332.0
HKD1_k127_2617985_11 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 336.0
HKD1_k127_2617985_12 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 336.0
HKD1_k127_2617985_13 Allophanate hydrolase subunit 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 316.0
HKD1_k127_2617985_14 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 300.0
HKD1_k127_2617985_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 300.0
HKD1_k127_2617985_16 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005132 299.0
HKD1_k127_2617985_17 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001193 284.0
HKD1_k127_2617985_18 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000147 289.0
HKD1_k127_2617985_19 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001519 267.0
HKD1_k127_2617985_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.099e-260 837.0
HKD1_k127_2617985_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001594 267.0
HKD1_k127_2617985_21 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001367 272.0
HKD1_k127_2617985_22 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000001502 255.0
HKD1_k127_2617985_23 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001002 263.0
HKD1_k127_2617985_24 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000002951 249.0
HKD1_k127_2617985_25 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000008015 231.0
HKD1_k127_2617985_26 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000003666 230.0
HKD1_k127_2617985_27 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000001121 206.0
HKD1_k127_2617985_28 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000001136 206.0
HKD1_k127_2617985_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000002245 209.0
HKD1_k127_2617985_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00244,K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 602.0
HKD1_k127_2617985_30 KR domain K07535 - - 0.000000000000000000000000000000000000000000000002469 198.0
HKD1_k127_2617985_31 Oxidoreductase NAD-binding domain K02823 - - 0.00000000000000000000000000000000000000000000004941 179.0
HKD1_k127_2617985_32 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000000001616 173.0
HKD1_k127_2617985_33 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000002232 170.0
HKD1_k127_2617985_34 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000005041 162.0
HKD1_k127_2617985_35 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000003224 162.0
HKD1_k127_2617985_36 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000001235 149.0
HKD1_k127_2617985_37 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000002939 143.0
HKD1_k127_2617985_38 Membrane domain of glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000006414 126.0
HKD1_k127_2617985_39 esterase K01070 - 3.1.2.12 0.0000000000000000000000000002682 128.0
HKD1_k127_2617985_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 581.0
HKD1_k127_2617985_40 membrane transporter protein K07090 - - 0.000000000000000000000000002347 115.0
HKD1_k127_2617985_41 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000001421 124.0
HKD1_k127_2617985_42 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000009409 111.0
HKD1_k127_2617985_43 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000618 63.0
HKD1_k127_2617985_44 - K03646 - - 0.00002944 56.0
HKD1_k127_2617985_45 AntiSigma factor - - - 0.00007059 52.0
HKD1_k127_2617985_46 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0001251 51.0
HKD1_k127_2617985_5 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 556.0
HKD1_k127_2617985_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 447.0
HKD1_k127_2617985_7 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 415.0
HKD1_k127_2617985_8 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 359.0
HKD1_k127_2617985_9 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 324.0
HKD1_k127_2620970_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1275.0
HKD1_k127_2620970_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.287e-202 650.0
HKD1_k127_2620970_10 Protein of unknown function (DUF2384) - - - 0.0000000000000000000003744 102.0
HKD1_k127_2620970_11 PFAM Peptidase M23 - - - 0.00000000000000005721 93.0
HKD1_k127_2620970_12 - - - - 0.000000000000002458 86.0
HKD1_k127_2620970_13 Heavy-metal resistance - - - 0.0000001776 59.0
HKD1_k127_2620970_14 O-Antigen ligase - - - 0.0003248 54.0
HKD1_k127_2620970_15 phosphatase 2C K01090 GO:0003674,GO:0003824,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050408,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.1.3.16 0.0003573 49.0
HKD1_k127_2620970_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 477.0
HKD1_k127_2620970_3 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 432.0
HKD1_k127_2620970_4 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 390.0
HKD1_k127_2620970_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 369.0
HKD1_k127_2620970_6 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000004467 219.0
HKD1_k127_2620970_7 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000001163 156.0
HKD1_k127_2620970_8 RES - - - 0.0000000000000000000000000000000000007695 151.0
HKD1_k127_2620970_9 - - - - 0.0000000000000000000001184 114.0
HKD1_k127_2625449_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.613e-288 909.0
HKD1_k127_2625449_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.989e-228 730.0
HKD1_k127_2625449_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000001947 240.0
HKD1_k127_2625449_11 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000004881 221.0
HKD1_k127_2625449_12 Peptidase S53 propeptide K08677 - - 0.00000000000000000000000000000000000000000000000000000004332 216.0
HKD1_k127_2625449_13 L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000002014 211.0
HKD1_k127_2625449_14 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000007915 198.0
HKD1_k127_2625449_15 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.000000000000000000000000000000000000000000000000003397 191.0
HKD1_k127_2625449_16 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000001301 188.0
HKD1_k127_2625449_17 Transmembrane and - - - 0.000000000000000000000000000000000000009766 168.0
HKD1_k127_2625449_18 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000008495 147.0
HKD1_k127_2625449_19 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000911 109.0
HKD1_k127_2625449_2 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 336.0
HKD1_k127_2625449_20 - - - - 0.0000000000000000000298 104.0
HKD1_k127_2625449_21 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000002638 93.0
HKD1_k127_2625449_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000000006805 82.0
HKD1_k127_2625449_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000005512 79.0
HKD1_k127_2625449_24 SNARE associated Golgi protein K03975 - - 0.0000000003092 62.0
HKD1_k127_2625449_25 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000006405 56.0
HKD1_k127_2625449_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 350.0
HKD1_k127_2625449_4 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 323.0
HKD1_k127_2625449_5 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001476 289.0
HKD1_k127_2625449_6 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001602 290.0
HKD1_k127_2625449_7 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003663 297.0
HKD1_k127_2625449_8 Transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001357 272.0
HKD1_k127_2625449_9 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000001029 250.0
HKD1_k127_2643037_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 561.0
HKD1_k127_2643037_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002958 289.0
HKD1_k127_2643037_2 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000306 179.0
HKD1_k127_2643037_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000005052 59.0
HKD1_k127_2643037_5 Protein kinase domain - - - 0.00000002919 59.0
HKD1_k127_264960_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 4.823e-218 689.0
HKD1_k127_264960_1 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 587.0
HKD1_k127_264960_10 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 366.0
HKD1_k127_264960_11 COG1879 ABC-type sugar transport system, periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 328.0
HKD1_k127_264960_12 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 343.0
HKD1_k127_264960_13 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 304.0
HKD1_k127_264960_14 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005567 282.0
HKD1_k127_264960_15 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001533 275.0
HKD1_k127_264960_16 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001464 273.0
HKD1_k127_264960_17 zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000001797 229.0
HKD1_k127_264960_18 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000000002789 208.0
HKD1_k127_264960_19 - - - - 0.000000000000000000000000000000000000000000000000000000004291 211.0
HKD1_k127_264960_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 596.0
HKD1_k127_264960_20 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000005208 203.0
HKD1_k127_264960_21 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000001019 211.0
HKD1_k127_264960_22 alpha beta - - - 0.000000000000000000000000000000000000000000000000000396 194.0
HKD1_k127_264960_23 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000005144 202.0
HKD1_k127_264960_24 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000002235 194.0
HKD1_k127_264960_25 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000000000000000000005108 160.0
HKD1_k127_264960_26 Haem-binding domain - - - 0.0000000000000000000000000000000000000000006876 162.0
HKD1_k127_264960_27 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000003997 162.0
HKD1_k127_264960_28 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000001271 158.0
HKD1_k127_264960_29 bleomycin resistance protein K01759 - 4.4.1.5 0.000000000000000000000000000000000000006402 148.0
HKD1_k127_264960_3 Belongs to the ribulokinase family K00853 - 2.7.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 570.0
HKD1_k127_264960_30 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000004484 163.0
HKD1_k127_264960_31 - - - - 0.000000000000000000000000000000000008494 148.0
HKD1_k127_264960_32 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000004046 144.0
HKD1_k127_264960_33 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000000000008077 150.0
HKD1_k127_264960_34 ester cyclase - - - 0.000000000000000000000000000000005337 143.0
HKD1_k127_264960_35 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000007905 129.0
HKD1_k127_264960_36 TfoX N-terminal domain - - - 0.0000000000000000000000001692 109.0
HKD1_k127_264960_37 - - - - 0.0000000000000003817 92.0
HKD1_k127_264960_38 Acetyltransferase (GNAT) domain - - - 0.0000000000000004617 83.0
HKD1_k127_264960_39 - - - - 0.000000000003232 69.0
HKD1_k127_264960_4 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 539.0
HKD1_k127_264960_42 - - - - 0.00008163 55.0
HKD1_k127_264960_43 Outer membrane protein beta-barrel family - - - 0.0002154 52.0
HKD1_k127_264960_5 COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent) K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 439.0
HKD1_k127_264960_6 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 436.0
HKD1_k127_264960_7 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 413.0
HKD1_k127_264960_8 protein conserved in bacteria K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 406.0
HKD1_k127_264960_9 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 368.0
HKD1_k127_2706008_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 9.515e-249 789.0
HKD1_k127_2706008_1 PFAM Leukotriene A4 hydrolase, C-terminal - - - 1.977e-213 683.0
HKD1_k127_2706008_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000001465 64.0
HKD1_k127_2706008_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 490.0
HKD1_k127_2706008_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 445.0
HKD1_k127_2706008_4 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 383.0
HKD1_k127_2706008_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006257 293.0
HKD1_k127_2706008_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001108 267.0
HKD1_k127_2706008_7 cation efflux K16264 - - 0.0000000000000000000000000000000000000000000000000000001132 223.0
HKD1_k127_2706008_8 Cytochrome c - - - 0.0000000000000000000000000001874 133.0
HKD1_k127_2706008_9 Outer membrane protein beta-barrel family K02014 - - 0.000000000000000000000009751 118.0
HKD1_k127_2714489_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 511.0
HKD1_k127_2714489_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 285.0
HKD1_k127_2714489_2 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000085 275.0
HKD1_k127_2714489_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
HKD1_k127_2714489_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000006318 115.0
HKD1_k127_2714489_5 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0006314 45.0
HKD1_k127_2780185_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 391.0
HKD1_k127_2780185_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 306.0
HKD1_k127_2780185_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003579 287.0
HKD1_k127_2780185_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001763 257.0
HKD1_k127_2780185_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001329 239.0
HKD1_k127_2780185_5 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000002885 196.0
HKD1_k127_2780185_6 Ketosteroid K06893 - - 0.0000000000000000000000000002496 123.0
HKD1_k127_2780185_7 - - - - 0.000000000000000000000002169 110.0
HKD1_k127_2780185_8 - - - - 0.000000000000000000000004114 107.0
HKD1_k127_2802388_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 587.0
HKD1_k127_2802388_1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009492 566.0
HKD1_k127_2802388_10 Thioesterase superfamily K18014 - 4.3.1.14 0.0000000000000000000000000000000000000008414 165.0
HKD1_k127_2802388_11 stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000001438 168.0
HKD1_k127_2802388_12 - - - - 0.000000000006152 76.0
HKD1_k127_2802388_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 443.0
HKD1_k127_2802388_3 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 347.0
HKD1_k127_2802388_4 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 360.0
HKD1_k127_2802388_5 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 332.0
HKD1_k127_2802388_6 alcohol dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 317.0
HKD1_k127_2802388_7 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 313.0
HKD1_k127_2802388_8 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000001305 263.0
HKD1_k127_2802388_9 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000001579 237.0
HKD1_k127_282831_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.174e-244 782.0
HKD1_k127_282831_1 Heat shock 70 kDa protein K04043 - - 3.628e-236 745.0
HKD1_k127_282831_10 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002879 280.0
HKD1_k127_282831_11 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001742 283.0
HKD1_k127_282831_12 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004919 272.0
HKD1_k127_282831_13 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
HKD1_k127_282831_14 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000002236 240.0
HKD1_k127_282831_15 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000001193 237.0
HKD1_k127_282831_16 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001497 246.0
HKD1_k127_282831_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000009385 233.0
HKD1_k127_282831_18 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000002872 211.0
HKD1_k127_282831_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000003091 198.0
HKD1_k127_282831_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 535.0
HKD1_k127_282831_20 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000329 188.0
HKD1_k127_282831_21 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000003506 178.0
HKD1_k127_282831_22 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000135 182.0
HKD1_k127_282831_23 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000003293 157.0
HKD1_k127_282831_24 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000001872 158.0
HKD1_k127_282831_25 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000001715 141.0
HKD1_k127_282831_26 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000000000000005303 134.0
HKD1_k127_282831_27 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000002879 136.0
HKD1_k127_282831_28 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000001379 129.0
HKD1_k127_282831_29 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000005723 124.0
HKD1_k127_282831_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 474.0
HKD1_k127_282831_30 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000004114 112.0
HKD1_k127_282831_31 RNA methyltransferase K09761 - 2.1.1.193 0.000000000000000001778 99.0
HKD1_k127_282831_32 Domain of unknown function (DUF2520) - - - 0.00000000000000002244 92.0
HKD1_k127_282831_33 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000181 81.0
HKD1_k127_282831_34 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.000000000000001142 80.0
HKD1_k127_282831_35 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000001093 80.0
HKD1_k127_282831_36 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.0000001432 59.0
HKD1_k127_282831_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 412.0
HKD1_k127_282831_5 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 401.0
HKD1_k127_282831_6 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 402.0
HKD1_k127_282831_7 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 359.0
HKD1_k127_282831_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 356.0
HKD1_k127_282831_9 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002164 300.0
HKD1_k127_3001029_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1144.0
HKD1_k127_3034710_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.201e-255 814.0
HKD1_k127_3034710_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.324e-252 804.0
HKD1_k127_3034710_10 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002416 239.0
HKD1_k127_3034710_11 Domain of unknown function (DUF4136) - - - 0.00000004472 67.0
HKD1_k127_3034710_12 Domain of unknown function (DUF4136) - - - 0.000000257 59.0
HKD1_k127_3034710_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 4.56e-242 777.0
HKD1_k127_3034710_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 625.0
HKD1_k127_3034710_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 564.0
HKD1_k127_3034710_5 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 576.0
HKD1_k127_3034710_6 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 531.0
HKD1_k127_3034710_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 509.0
HKD1_k127_3034710_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 358.0
HKD1_k127_3034710_9 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
HKD1_k127_3034736_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 391.0
HKD1_k127_3034736_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007998 263.0
HKD1_k127_3078172_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.449e-247 796.0
HKD1_k127_3078172_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 9.137e-243 760.0
HKD1_k127_3078172_10 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 315.0
HKD1_k127_3078172_11 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 293.0
HKD1_k127_3078172_12 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004741 272.0
HKD1_k127_3078172_13 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
HKD1_k127_3078172_14 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000004144 252.0
HKD1_k127_3078172_15 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000006933 247.0
HKD1_k127_3078172_16 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000198 220.0
HKD1_k127_3078172_17 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000002153 223.0
HKD1_k127_3078172_18 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000002326 197.0
HKD1_k127_3078172_19 - - - - 0.00000000000000000000000000000000000000000000000001181 198.0
HKD1_k127_3078172_2 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 529.0
HKD1_k127_3078172_20 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000005245 190.0
HKD1_k127_3078172_21 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000002016 173.0
HKD1_k127_3078172_22 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000006271 155.0
HKD1_k127_3078172_23 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000000002642 156.0
HKD1_k127_3078172_24 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000002063 138.0
HKD1_k127_3078172_25 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000002596 139.0
HKD1_k127_3078172_26 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000007733 129.0
HKD1_k127_3078172_27 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000004392 115.0
HKD1_k127_3078172_28 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000002003 128.0
HKD1_k127_3078172_29 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.000000000000000000000000009457 119.0
HKD1_k127_3078172_3 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 512.0
HKD1_k127_3078172_30 DSBA-like thioredoxin domain - - - 0.00000000000001188 85.0
HKD1_k127_3078172_31 Thioredoxin - - - 0.000000000002198 74.0
HKD1_k127_3078172_32 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000002302 55.0
HKD1_k127_3078172_33 Domain of unknown function (DUF4340) - - - 0.00001382 57.0
HKD1_k127_3078172_34 O-antigen ligase - - - 0.0002124 53.0
HKD1_k127_3078172_4 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 488.0
HKD1_k127_3078172_5 COG0464 ATPases of the AAA class - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 417.0
HKD1_k127_3078172_6 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 432.0
HKD1_k127_3078172_7 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 394.0
HKD1_k127_3078172_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 363.0
HKD1_k127_3078172_9 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 343.0
HKD1_k127_3110425_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 383.0
HKD1_k127_3110425_1 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 358.0
HKD1_k127_3110425_10 Type II transport protein GspH K08084 - - 0.0001116 51.0
HKD1_k127_3110425_2 twitching motility protein K02669 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 354.0
HKD1_k127_3110425_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 342.0
HKD1_k127_3110425_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000004318 220.0
HKD1_k127_3110425_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000009188 148.0
HKD1_k127_3110425_6 Type IV fimbrial biogenesis protein PilY1 K02674 - - 0.00000000000000000000000000000031 145.0
HKD1_k127_3110425_7 Bacterial membrane protein, YfhO - - - 0.0000000000001484 84.0
HKD1_k127_3110425_8 Est1 DNA/RNA binding domain - GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377 - 0.00000006064 66.0
HKD1_k127_3110425_9 Pilus assembly protein PilX K02673 - - 0.00008575 55.0
HKD1_k127_3152217_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 583.0
HKD1_k127_3152217_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 362.0
HKD1_k127_3152217_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.00000000000000000000005019 104.0
HKD1_k127_3152217_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000002199 67.0
HKD1_k127_3152217_12 DNA polymerase III, delta' K02340 - 2.7.7.7 0.000003097 59.0
HKD1_k127_3152217_2 transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 334.0
HKD1_k127_3152217_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000654 259.0
HKD1_k127_3152217_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000456 248.0
HKD1_k127_3152217_5 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000009561 216.0
HKD1_k127_3152217_6 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000003594 201.0
HKD1_k127_3152217_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000258 175.0
HKD1_k127_3152217_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000001368 137.0
HKD1_k127_3152217_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000374 110.0
HKD1_k127_3154287_0 Carboxypeptidase regulatory-like domain - - - 8.484e-198 650.0
HKD1_k127_3154287_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 524.0
HKD1_k127_3154287_10 - - - - 0.0000000000000000000000000000000000000000001414 167.0
HKD1_k127_3154287_11 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000079 124.0
HKD1_k127_3154287_12 DREV methyltransferase - - - 0.00000000000000000000000001206 118.0
HKD1_k127_3154287_13 antibiotic catabolic process K18235 - - 0.0000003145 64.0
HKD1_k127_3154287_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0002944 52.0
HKD1_k127_3154287_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 493.0
HKD1_k127_3154287_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 363.0
HKD1_k127_3154287_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 361.0
HKD1_k127_3154287_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001142 285.0
HKD1_k127_3154287_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004755 275.0
HKD1_k127_3154287_7 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000002773 246.0
HKD1_k127_3154287_8 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000003404 228.0
HKD1_k127_3154287_9 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000003635 184.0
HKD1_k127_3167474_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 434.0
HKD1_k127_3167474_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 389.0
HKD1_k127_3187034_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 426.0
HKD1_k127_3187034_1 MOSC domain - - - 0.000000000000000000000000000000000000000000000000005315 188.0
HKD1_k127_3187034_2 Thioesterase K01075 - 3.1.2.23 0.00000000000000000000001593 104.0
HKD1_k127_3187034_3 - - - - 0.00000000000000001038 91.0
HKD1_k127_3187034_4 - - - - 0.00000000115 60.0
HKD1_k127_3187034_5 Bacterial regulatory proteins, tetR family - - - 0.00000007177 59.0
HKD1_k127_3187034_6 PilZ domain - - - 0.000003847 53.0
HKD1_k127_320410_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 605.0
HKD1_k127_320410_1 ERAP1-like C-terminal domain K01263 - 3.4.11.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 385.0
HKD1_k127_320410_2 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000003605 155.0
HKD1_k127_3213182_0 Involved in the tonB-independent uptake of proteins - - - 3.691e-233 749.0
HKD1_k127_3213182_1 Involved in the tonB-independent uptake of proteins - - - 1.602e-221 715.0
HKD1_k127_3213182_10 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002347 277.0
HKD1_k127_3213182_11 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000682 244.0
HKD1_k127_3213182_12 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000001592 204.0
HKD1_k127_3213182_13 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000002492 207.0
HKD1_k127_3213182_14 CGNR zinc finger - - - 0.000000000000000000000000000003859 127.0
HKD1_k127_3213182_15 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.0000000000000000000000000001098 132.0
HKD1_k127_3213182_16 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000005419 117.0
HKD1_k127_3213182_17 Sodium:solute symporter family K03307 - - 0.000000000000000000002329 108.0
HKD1_k127_3213182_18 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000001283 108.0
HKD1_k127_3213182_19 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000006413 98.0
HKD1_k127_3213182_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 1.635e-201 653.0
HKD1_k127_3213182_20 Virulence activator alpha C-term - - - 0.0000000000000009014 84.0
HKD1_k127_3213182_21 - - - - 0.000000000000004488 85.0
HKD1_k127_3213182_22 Putative zinc-finger - - - 0.00000261 58.0
HKD1_k127_3213182_23 Domain of unknown function (DUF4149) - - - 0.00001842 54.0
HKD1_k127_3213182_3 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 349.0
HKD1_k127_3213182_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 318.0
HKD1_k127_3213182_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 324.0
HKD1_k127_3213182_6 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 313.0
HKD1_k127_3213182_7 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 291.0
HKD1_k127_3213182_8 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000006927 270.0
HKD1_k127_3213182_9 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001637 280.0
HKD1_k127_3267297_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 371.0
HKD1_k127_3267297_1 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 350.0
HKD1_k127_3267297_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001419 297.0
HKD1_k127_3267297_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000004924 68.0
HKD1_k127_3267297_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000003532 70.0
HKD1_k127_3267297_5 MFS/sugar transport protein K03292 - - 0.00003797 55.0
HKD1_k127_3275774_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.175e-286 904.0
HKD1_k127_3275774_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.105e-244 783.0
HKD1_k127_3275774_10 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006908 263.0
HKD1_k127_3275774_11 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000002928 231.0
HKD1_k127_3275774_12 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000456 233.0
HKD1_k127_3275774_13 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000001755 236.0
HKD1_k127_3275774_14 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000003651 218.0
HKD1_k127_3275774_15 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000001785 210.0
HKD1_k127_3275774_16 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway - - - 0.000000000000000000000000000000000000000000000000002287 188.0
HKD1_k127_3275774_17 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000007579 196.0
HKD1_k127_3275774_18 Doxx family K15977 - - 0.000000000000000000000000000000000000000000000006876 181.0
HKD1_k127_3275774_19 Doxx family K15977 - - 0.0000000000000000000000000000000000000000000001273 172.0
HKD1_k127_3275774_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 5.841e-196 618.0
HKD1_k127_3275774_20 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000003905 153.0
HKD1_k127_3275774_21 Radical SAM superfamily - - - 0.00000000000000000000000000000000004444 154.0
HKD1_k127_3275774_22 Protein conserved in bacteria - - - 0.0000000000000000000000000000000002978 136.0
HKD1_k127_3275774_23 Iron-sulfur cluster-binding domain - - - 0.00000000000000000001789 106.0
HKD1_k127_3275774_24 Glycosyl transferase, family 2 - - - 0.0000000000000001424 90.0
HKD1_k127_3275774_26 methyltransferase - - - 0.00000000003361 72.0
HKD1_k127_3275774_28 - - - - 0.00000002334 61.0
HKD1_k127_3275774_3 Major facilitator superfamily K08167 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 589.0
HKD1_k127_3275774_4 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 543.0
HKD1_k127_3275774_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 469.0
HKD1_k127_3275774_6 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 415.0
HKD1_k127_3275774_7 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 438.0
HKD1_k127_3275774_8 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 356.0
HKD1_k127_3283738_0 phosphoserine phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 455.0
HKD1_k127_3283738_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000005919 126.0
HKD1_k127_3327587_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 525.0
HKD1_k127_3327587_1 Oligoendopeptidase f - - - 0.00000000000000000000000000000000000000000005858 162.0
HKD1_k127_3553587_0 Involved in the tonB-independent uptake of proteins - - - 1.915e-232 747.0
HKD1_k127_3553587_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005773 273.0
HKD1_k127_362709_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.777e-237 760.0
HKD1_k127_362709_1 Peptidase family M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 611.0
HKD1_k127_362709_10 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003181 295.0
HKD1_k127_362709_11 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006064 298.0
HKD1_k127_362709_12 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000005656 255.0
HKD1_k127_362709_13 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000002081 265.0
HKD1_k127_362709_14 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000002501 265.0
HKD1_k127_362709_15 Belongs to the FPG family K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000007676 232.0
HKD1_k127_362709_16 sugar phosphatases of the HAD superfamily K02566 - - 0.000000000000000000000000000000000000000000000000000000000001276 233.0
HKD1_k127_362709_17 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000001401 203.0
HKD1_k127_362709_18 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000001087 202.0
HKD1_k127_362709_19 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000001701 196.0
HKD1_k127_362709_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 607.0
HKD1_k127_362709_20 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000006297 196.0
HKD1_k127_362709_21 prohibitin homologues - - - 0.000000000000000000000000000000000000000000007629 189.0
HKD1_k127_362709_22 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000003019 154.0
HKD1_k127_362709_23 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000063 159.0
HKD1_k127_362709_24 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000005602 155.0
HKD1_k127_362709_25 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000002829 134.0
HKD1_k127_362709_26 Metallo-peptidase family M12 - - - 0.000000000000000000000000000001043 141.0
HKD1_k127_362709_27 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.000000000000000000000000000007766 134.0
HKD1_k127_362709_28 Dienelactone hydrolase family - - - 0.00000000000000000000000000003833 135.0
HKD1_k127_362709_29 - - - - 0.0000000000000000000000000002686 117.0
HKD1_k127_362709_3 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 585.0
HKD1_k127_362709_30 domain protein - - - 0.0000000000000003554 91.0
HKD1_k127_362709_31 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000003919 87.0
HKD1_k127_362709_32 Sporulation and spore germination - - - 0.00000000000007609 85.0
HKD1_k127_362709_34 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00004284 57.0
HKD1_k127_362709_35 AsmA family K07289 - - 0.0002769 49.0
HKD1_k127_362709_36 BlaR1 peptidase M56 - - - 0.00036 52.0
HKD1_k127_362709_4 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 505.0
HKD1_k127_362709_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 481.0
HKD1_k127_362709_6 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 389.0
HKD1_k127_362709_7 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 382.0
HKD1_k127_362709_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 374.0
HKD1_k127_362709_9 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 376.0
HKD1_k127_3748242_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 579.0
HKD1_k127_3748242_1 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 351.0
HKD1_k127_3748242_10 - - - - 0.0000000000000000000000000000000000000000000000000005249 193.0
HKD1_k127_3748242_11 - - - - 0.000000000000000000000000000000000000000000000003032 176.0
HKD1_k127_3748242_12 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000001098 141.0
HKD1_k127_3748242_13 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000004045 143.0
HKD1_k127_3748242_14 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000000000172 131.0
HKD1_k127_3748242_15 - - - - 0.0000000000000000000000000000002052 126.0
HKD1_k127_3748242_17 - - - - 0.00000000000000004779 86.0
HKD1_k127_3748242_18 Domain of unknown function (DU1801) - - - 0.0000000000000000876 83.0
HKD1_k127_3748242_19 Glyoxalase-like domain - - - 0.00000000000001597 78.0
HKD1_k127_3748242_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 331.0
HKD1_k127_3748242_20 Acetyltransferase (GNAT) family K03395 - 2.3.1.60 0.000000000009081 72.0
HKD1_k127_3748242_21 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000009969 71.0
HKD1_k127_3748242_22 Cupin domain K21700 - - 0.00009136 53.0
HKD1_k127_3748242_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 308.0
HKD1_k127_3748242_4 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 289.0
HKD1_k127_3748242_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000001003 241.0
HKD1_k127_3748242_6 - - - - 0.00000000000000000000000000000000000000000000000000000000002607 208.0
HKD1_k127_3748242_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001012 211.0
HKD1_k127_3748242_8 DoxX-like family - - - 0.0000000000000000000000000000000000000000000000000000003556 197.0
HKD1_k127_3748242_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000001555 186.0
HKD1_k127_3827932_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 407.0
HKD1_k127_3827932_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000491 236.0
HKD1_k127_3827932_2 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009783 254.0
HKD1_k127_3827932_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000001234 255.0
HKD1_k127_3961237_0 Zinc carboxypeptidase - - - 7.469e-229 744.0
HKD1_k127_3961237_1 lysine biosynthetic process via aminoadipic acid - - - 8.113e-228 727.0
HKD1_k127_3961237_10 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 344.0
HKD1_k127_3961237_11 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 314.0
HKD1_k127_3961237_12 PFAM ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 314.0
HKD1_k127_3961237_13 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005571 299.0
HKD1_k127_3961237_14 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001643 298.0
HKD1_k127_3961237_15 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007923 274.0
HKD1_k127_3961237_16 Protein of unknown function (DUF4243) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003417 252.0
HKD1_k127_3961237_17 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000001238 233.0
HKD1_k127_3961237_18 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000001475 202.0
HKD1_k127_3961237_19 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000003538 207.0
HKD1_k127_3961237_2 Insulinase (Peptidase family M16) - - - 7.207e-194 638.0
HKD1_k127_3961237_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000003059 193.0
HKD1_k127_3961237_21 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000001046 195.0
HKD1_k127_3961237_22 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000002667 153.0
HKD1_k127_3961237_23 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000006772 174.0
HKD1_k127_3961237_24 DinB superfamily - - - 0.000000000000000000000000000000000002508 144.0
HKD1_k127_3961237_25 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000006378 141.0
HKD1_k127_3961237_26 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000009442 154.0
HKD1_k127_3961237_27 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000003327 138.0
HKD1_k127_3961237_28 - K01992,K19341 - - 0.000000000000000000000000000000000296 151.0
HKD1_k127_3961237_29 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000007759 145.0
HKD1_k127_3961237_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K21624 - 4.2.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 583.0
HKD1_k127_3961237_30 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000000000001055 141.0
HKD1_k127_3961237_31 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000000000000000000001062 120.0
HKD1_k127_3961237_32 STAS domain K04749 - - 0.00000000007252 72.0
HKD1_k127_3961237_33 - - - - 0.00071 52.0
HKD1_k127_3961237_4 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 459.0
HKD1_k127_3961237_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 404.0
HKD1_k127_3961237_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
HKD1_k127_3961237_7 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 367.0
HKD1_k127_3961237_8 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
HKD1_k127_3961237_9 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 345.0
HKD1_k127_3975894_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1066.0
HKD1_k127_3975894_1 gluconolactonase activity K01053,K13735 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 581.0
HKD1_k127_3975894_10 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000000000000004473 196.0
HKD1_k127_3975894_11 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000002984 209.0
HKD1_k127_3975894_12 Activator of hsp90 atpase 1 family protein - - - 0.00000000000000000000000000000000000000000000001725 178.0
HKD1_k127_3975894_14 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000002456 166.0
HKD1_k127_3975894_15 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000008405 166.0
HKD1_k127_3975894_16 methyltransferase activity - - - 0.000000000000000000000000000000000000004638 153.0
HKD1_k127_3975894_17 DinB family - - - 0.000000000000000000000000000000000000007451 162.0
HKD1_k127_3975894_18 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000007677 141.0
HKD1_k127_3975894_19 OsmC-like protein - - - 0.00000000000000000000000000000000003705 141.0
HKD1_k127_3975894_2 Cystathionine beta-synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 422.0
HKD1_k127_3975894_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000005466 126.0
HKD1_k127_3975894_21 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000007538 124.0
HKD1_k127_3975894_22 Methyltransferase domain - - - 0.0000000000000000000000000001485 127.0
HKD1_k127_3975894_23 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000006363 112.0
HKD1_k127_3975894_24 acetyltransferase - - - 0.000000000000000000004985 101.0
HKD1_k127_3975894_25 - - - - 0.0000000000000000005311 87.0
HKD1_k127_3975894_26 DinB family - - - 0.00000000000001436 81.0
HKD1_k127_3975894_27 Domain of unknown function (DUF4440) - - - 0.0003329 49.0
HKD1_k127_3975894_3 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 391.0
HKD1_k127_3975894_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 287.0
HKD1_k127_3975894_5 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000271 264.0
HKD1_k127_3975894_6 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002716 267.0
HKD1_k127_3975894_7 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008247 252.0
HKD1_k127_3975894_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
HKD1_k127_3975894_9 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000005173 227.0
HKD1_k127_4017128_0 PFAM peptidase M13 K01415 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 390.0
HKD1_k127_4017128_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003812 259.0
HKD1_k127_4017128_2 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000542 239.0
HKD1_k127_4017128_3 AsmA family K07289 - - 0.0000000348 65.0
HKD1_k127_4031406_0 Phosphoesterase family - - - 1.368e-218 709.0
HKD1_k127_4031406_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 5.784e-217 682.0
HKD1_k127_4031406_10 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000003131 158.0
HKD1_k127_4031406_11 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000002624 147.0
HKD1_k127_4031406_12 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.000000000000000000000004696 108.0
HKD1_k127_4031406_13 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000001885 104.0
HKD1_k127_4031406_14 - - - - 0.0000000000006545 75.0
HKD1_k127_4031406_15 PFAM secretion protein HlyD family protein K01993 - - 0.000000000007133 79.0
HKD1_k127_4031406_16 - - - - 0.0000003988 56.0
HKD1_k127_4031406_17 peptidyl-tyrosine sulfation - - - 0.000001845 60.0
HKD1_k127_4031406_2 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 406.0
HKD1_k127_4031406_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 293.0
HKD1_k127_4031406_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002998 267.0
HKD1_k127_4031406_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 246.0
HKD1_k127_4031406_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000002499 257.0
HKD1_k127_4031406_7 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000004638 220.0
HKD1_k127_4031406_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000002635 199.0
HKD1_k127_4031406_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000002341 194.0
HKD1_k127_4037376_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 483.0
HKD1_k127_4037376_1 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000000000000139 209.0
HKD1_k127_4037376_2 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000009288 145.0
HKD1_k127_4092444_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 622.0
HKD1_k127_4092444_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 559.0
HKD1_k127_4092444_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 420.0
HKD1_k127_4092444_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 345.0
HKD1_k127_4092444_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000475 219.0
HKD1_k127_4092444_5 Response regulator receiver domain - - - 0.0000000000000004699 90.0
HKD1_k127_4092444_6 Protein of unknown function (DUF3309) - - - 0.000000000000001014 81.0
HKD1_k127_4092444_7 peptidase inhibitor activity - - - 0.000000000000002603 91.0
HKD1_k127_4174400_0 PFAM 4Fe-4S K00184,K21308 - - 0.0 1062.0
HKD1_k127_4174400_1 Polysulphide reductase, NrfD K00185 - - 2.506e-202 682.0
HKD1_k127_4174400_10 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000001122 160.0
HKD1_k127_4174400_11 Iron--sulfur cluster insertion protein erpA K15724 - - 0.0000000000000000000000004953 108.0
HKD1_k127_4174400_14 Peptidase M56 - - - 0.0000000000000002108 94.0
HKD1_k127_4174400_15 Peptidase M56 - - - 0.0000000000000009042 92.0
HKD1_k127_4174400_16 Peptidase M56 - - - 0.00000000000006483 83.0
HKD1_k127_4174400_17 Peptidase M56 - - - 0.000000000001591 81.0
HKD1_k127_4174400_18 - - - - 0.000000004959 64.0
HKD1_k127_4174400_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 425.0
HKD1_k127_4174400_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 400.0
HKD1_k127_4174400_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 399.0
HKD1_k127_4174400_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 372.0
HKD1_k127_4174400_6 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 325.0
HKD1_k127_4174400_7 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 302.0
HKD1_k127_4174400_8 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000003861 247.0
HKD1_k127_4174400_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000002721 215.0
HKD1_k127_4200593_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 383.0
HKD1_k127_4200593_1 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001311 279.0
HKD1_k127_4200593_2 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000005167 121.0
HKD1_k127_4221524_0 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 361.0
HKD1_k127_4221524_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 333.0
HKD1_k127_4221524_10 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000001975 122.0
HKD1_k127_4221524_11 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000000007342 98.0
HKD1_k127_4221524_12 chaperone-mediated protein folding - - - 0.0000000000001462 85.0
HKD1_k127_4221524_13 Tetratricopeptide repeat - - - 0.0000000000001505 85.0
HKD1_k127_4221524_14 Protein of unknown function (FYDLN_acid) - - - 0.000000000001675 71.0
HKD1_k127_4221524_15 'glutamate synthase - - - 0.00001184 51.0
HKD1_k127_4221524_16 long-chain fatty acid transporting porin activity K06076 - - 0.0001816 53.0
HKD1_k127_4221524_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 314.0
HKD1_k127_4221524_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
HKD1_k127_4221524_4 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000007026 175.0
HKD1_k127_4221524_5 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000004698 153.0
HKD1_k127_4221524_6 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.0000000000000000000000000000000006233 144.0
HKD1_k127_4221524_7 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000004327 140.0
HKD1_k127_4221524_8 Diguanylate cyclase - - - 0.000000000000000000000000007513 128.0
HKD1_k127_4221524_9 Belongs to the Fur family K09825 - - 0.0000000000000000000000001101 111.0
HKD1_k127_4222146_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 336.0
HKD1_k127_4222146_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007035 292.0
HKD1_k127_4222146_2 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000007957 248.0
HKD1_k127_4222146_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004677 255.0
HKD1_k127_4222146_4 Peptidase, M16 - - - 0.000000000000000000000000000000000000000000000000000000445 196.0
HKD1_k127_4222146_5 HlyD membrane-fusion protein of T1SS K01993 - - 0.000000000000000000000000000000000000000000008212 188.0
HKD1_k127_4222146_6 outer membrane efflux protein - - - 0.00000000000000000000000000000006379 144.0
HKD1_k127_4222146_7 Bacterial regulatory proteins, tetR family - - - 0.000004417 56.0
HKD1_k127_4231774_0 Belongs to the GPI family K01810 - 5.3.1.9 1.448e-270 842.0
HKD1_k127_4231774_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.329e-200 632.0
HKD1_k127_4231774_10 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001689 265.0
HKD1_k127_4231774_11 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) K00851,K01807 - 2.7.1.12,5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000006272 279.0
HKD1_k127_4231774_12 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000008975 252.0
HKD1_k127_4231774_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001947 237.0
HKD1_k127_4231774_14 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000008651 123.0
HKD1_k127_4231774_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000001008 102.0
HKD1_k127_4231774_16 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000002534 104.0
HKD1_k127_4231774_17 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000002113 90.0
HKD1_k127_4231774_18 PFAM regulatory protein, MerR - - - 0.000000000000006783 81.0
HKD1_k127_4231774_19 Aminotransferase class-III K09251 - 2.6.1.82 0.0000000000008059 70.0
HKD1_k127_4231774_2 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 608.0
HKD1_k127_4231774_20 - - - - 0.00000000001343 72.0
HKD1_k127_4231774_21 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000001781 58.0
HKD1_k127_4231774_22 COG3794 Plastocyanin - - - 0.0001948 53.0
HKD1_k127_4231774_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 602.0
HKD1_k127_4231774_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 571.0
HKD1_k127_4231774_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 376.0
HKD1_k127_4231774_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 347.0
HKD1_k127_4231774_7 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 311.0
HKD1_k127_4231774_8 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000495 280.0
HKD1_k127_4231774_9 soluble inorganic K01507 GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0008150,GO:0010035,GO:0010038,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005179 261.0
HKD1_k127_4239559_0 esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 441.0
HKD1_k127_4239559_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 304.0
HKD1_k127_4239559_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008016 291.0
HKD1_k127_4239559_3 PFAM Beta-propeller repeat - - - 0.000000000000001053 90.0
HKD1_k127_4239559_6 Domain of unknown function DUF302 - - - 0.0000009853 51.0
HKD1_k127_4239559_7 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00002292 57.0
HKD1_k127_4267437_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 511.0
HKD1_k127_4267437_1 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 469.0
HKD1_k127_4267437_2 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 452.0
HKD1_k127_4267437_3 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 419.0
HKD1_k127_4267437_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 378.0
HKD1_k127_4267437_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 372.0
HKD1_k127_4267437_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000001235 231.0
HKD1_k127_4267437_7 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.000000000000000000000000000000000000005274 157.0
HKD1_k127_4267437_8 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000001459 161.0
HKD1_k127_4348516_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 6e-238 746.0
HKD1_k127_4348516_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.751e-199 635.0
HKD1_k127_4348516_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 515.0
HKD1_k127_4348516_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 355.0
HKD1_k127_4348516_4 PFAM Serine threonine protein kinase-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008556 298.0
HKD1_k127_4348516_5 Molybdopterin oxidoreductase - - - 0.0000000000000000000000000000001646 126.0
HKD1_k127_4422487_0 choline dehydrogenase activity - - - 3.737e-252 805.0
HKD1_k127_4422487_1 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 603.0
HKD1_k127_4422487_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000002262 205.0
HKD1_k127_4422487_11 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000007435 188.0
HKD1_k127_4422487_12 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000004401 159.0
HKD1_k127_4422487_13 TonB dependent receptor K02014,K16087 - - 0.00000000000000000000000000000001624 147.0
HKD1_k127_4422487_14 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000001311 134.0
HKD1_k127_4422487_15 Putative DNA-binding domain - - - 0.0000000000000000000000003546 119.0
HKD1_k127_4422487_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000004196 94.0
HKD1_k127_4422487_17 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.00000000000001426 87.0
HKD1_k127_4422487_18 Putative DNA-binding domain - - - 0.00000000000006514 83.0
HKD1_k127_4422487_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000001065 76.0
HKD1_k127_4422487_2 transcription factor binding K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 468.0
HKD1_k127_4422487_20 - - - - 0.0000000007329 69.0
HKD1_k127_4422487_21 Putative zinc-finger - - - 0.000000003385 61.0
HKD1_k127_4422487_22 - - - - 0.000001259 60.0
HKD1_k127_4422487_3 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 418.0
HKD1_k127_4422487_4 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 370.0
HKD1_k127_4422487_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 387.0
HKD1_k127_4422487_6 gluconolactonase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 387.0
HKD1_k127_4422487_7 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 338.0
HKD1_k127_4422487_8 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 328.0
HKD1_k127_4422487_9 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008837 298.0
HKD1_k127_4839444_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1380.0
HKD1_k127_4839444_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.226e-287 894.0
HKD1_k127_4839444_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 339.0
HKD1_k127_4839444_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 342.0
HKD1_k127_4839444_12 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 319.0
HKD1_k127_4839444_13 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 304.0
HKD1_k127_4839444_14 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001525 281.0
HKD1_k127_4839444_15 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005071 258.0
HKD1_k127_4839444_16 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
HKD1_k127_4839444_17 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000005326 223.0
HKD1_k127_4839444_18 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000001099 187.0
HKD1_k127_4839444_19 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000002943 198.0
HKD1_k127_4839444_2 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.198e-275 871.0
HKD1_k127_4839444_20 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000000002041 185.0
HKD1_k127_4839444_21 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000001052 179.0
HKD1_k127_4839444_22 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000003501 171.0
HKD1_k127_4839444_23 Membrane - - - 0.00000000000000000000000000000000000000003595 171.0
HKD1_k127_4839444_24 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000006971 156.0
HKD1_k127_4839444_25 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000002592 147.0
HKD1_k127_4839444_27 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000001951 155.0
HKD1_k127_4839444_28 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000002101 154.0
HKD1_k127_4839444_29 DinB family - - - 0.00000000000000000000000000000000006338 141.0
HKD1_k127_4839444_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 621.0
HKD1_k127_4839444_30 Transcriptional regulator - - - 0.000000000000000000000000000002352 129.0
HKD1_k127_4839444_31 Protein of unknown function (DUF1272) K09984 - - 0.000000000000000000000000000006134 138.0
HKD1_k127_4839444_32 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000125 130.0
HKD1_k127_4839444_33 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000004081 128.0
HKD1_k127_4839444_35 Alpha beta hydrolase - - - 0.00000000000000000002323 103.0
HKD1_k127_4839444_37 Transcriptional regulator, AraC family K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.000000000000000009107 90.0
HKD1_k127_4839444_38 gluconolactonase activity - - - 0.0000000000000002987 92.0
HKD1_k127_4839444_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 599.0
HKD1_k127_4839444_40 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000001656 73.0
HKD1_k127_4839444_41 peptidyl-tyrosine sulfation - - - 0.000001066 63.0
HKD1_k127_4839444_5 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 479.0
HKD1_k127_4839444_6 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 399.0
HKD1_k127_4839444_7 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 408.0
HKD1_k127_4839444_8 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 398.0
HKD1_k127_4839444_9 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 349.0
HKD1_k127_4840588_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.024e-266 835.0
HKD1_k127_4840588_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 521.0
HKD1_k127_4840588_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 501.0
HKD1_k127_485131_0 Hydrolase CocE NonD family - - - 9.609e-312 972.0
HKD1_k127_485131_1 tRNA synthetases class I (K) K01870 - 6.1.1.5 6.364e-280 889.0
HKD1_k127_485131_10 Pfam:Arch_ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
HKD1_k127_485131_11 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009692 285.0
HKD1_k127_485131_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000002488 260.0
HKD1_k127_485131_13 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000974 271.0
HKD1_k127_485131_14 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000122 226.0
HKD1_k127_485131_15 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000005042 228.0
HKD1_k127_485131_16 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000003743 217.0
HKD1_k127_485131_17 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000002084 227.0
HKD1_k127_485131_18 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000008317 220.0
HKD1_k127_485131_19 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000004553 180.0
HKD1_k127_485131_2 Peptidase family M13 K07386 - - 3.81e-253 801.0
HKD1_k127_485131_20 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000004575 176.0
HKD1_k127_485131_21 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000001251 178.0
HKD1_k127_485131_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000002335 159.0
HKD1_k127_485131_23 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000003086 163.0
HKD1_k127_485131_24 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000009255 138.0
HKD1_k127_485131_25 FecR protein - - - 0.000000000000000000000000000008868 138.0
HKD1_k127_485131_26 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000003569 114.0
HKD1_k127_485131_27 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000004955 104.0
HKD1_k127_485131_28 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000996 83.0
HKD1_k127_485131_29 - - - - 0.000000000000001024 92.0
HKD1_k127_485131_3 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.842e-194 614.0
HKD1_k127_485131_30 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000004056 84.0
HKD1_k127_485131_31 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.00000000000005288 72.0
HKD1_k127_485131_32 NUDIX domain - - - 0.0000000000006545 75.0
HKD1_k127_485131_34 Transcriptional regulatory protein, C terminal - - - 0.000001894 53.0
HKD1_k127_485131_35 Putative adhesin - - - 0.000007279 57.0
HKD1_k127_485131_4 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 553.0
HKD1_k127_485131_5 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 479.0
HKD1_k127_485131_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 469.0
HKD1_k127_485131_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 460.0
HKD1_k127_485131_8 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 412.0
HKD1_k127_485131_9 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 302.0
HKD1_k127_4858152_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 9.563e-294 927.0
HKD1_k127_4858152_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.969e-238 759.0
HKD1_k127_4858152_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002746 263.0
HKD1_k127_4858152_11 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002071 246.0
HKD1_k127_4858152_12 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000001109 236.0
HKD1_k127_4858152_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000004647 195.0
HKD1_k127_4858152_14 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000001519 140.0
HKD1_k127_4858152_15 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000006452 121.0
HKD1_k127_4858152_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000001081 124.0
HKD1_k127_4858152_17 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000005335 99.0
HKD1_k127_4858152_18 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000007842 86.0
HKD1_k127_4858152_19 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000003687 80.0
HKD1_k127_4858152_2 AMP-binding enzyme C-terminal domain K00666 - - 2.118e-233 733.0
HKD1_k127_4858152_20 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.00000000002376 75.0
HKD1_k127_4858152_22 semaphorin-plexin signaling pathway - - - 0.0002739 53.0
HKD1_k127_4858152_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 589.0
HKD1_k127_4858152_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 442.0
HKD1_k127_4858152_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 379.0
HKD1_k127_4858152_6 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 340.0
HKD1_k127_4858152_7 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 342.0
HKD1_k127_4858152_8 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 297.0
HKD1_k127_4858152_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001125 285.0
HKD1_k127_4899267_0 PFAM Na-Ca exchanger integrin-beta4 - - - 3.57e-237 792.0
HKD1_k127_4899267_1 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 603.0
HKD1_k127_4899267_10 Amidohydrolase - - - 0.00000000000000000000000000001694 132.0
HKD1_k127_4899267_11 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000008793 126.0
HKD1_k127_4899267_12 - - - - 0.00000002049 64.0
HKD1_k127_4899267_13 Phospholipase_D-nuclease N-terminal - - - 0.0000003315 56.0
HKD1_k127_4899267_2 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 514.0
HKD1_k127_4899267_3 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 486.0
HKD1_k127_4899267_4 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 403.0
HKD1_k127_4899267_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 385.0
HKD1_k127_4899267_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 305.0
HKD1_k127_4899267_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006382 279.0
HKD1_k127_4899267_8 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000002476 244.0
HKD1_k127_4899267_9 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000001438 138.0
HKD1_k127_5044026_0 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 381.0
HKD1_k127_5044026_1 PFAM ASPIC and UnbV - - - 0.000000000000000000000000000000000008246 151.0
HKD1_k127_5046820_0 Polysaccharide biosynthesis protein CapD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 519.0
HKD1_k127_5046820_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 478.0
HKD1_k127_5046820_10 methyltransferase K15471 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.000000000000000000000000000000002739 148.0
HKD1_k127_5046820_11 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000889 147.0
HKD1_k127_5046820_12 - - - - 0.0000000526 64.0
HKD1_k127_5046820_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 456.0
HKD1_k127_5046820_3 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 441.0
HKD1_k127_5046820_4 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 318.0
HKD1_k127_5046820_5 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005094 274.0
HKD1_k127_5046820_6 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000005684 256.0
HKD1_k127_5046820_7 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000002149 179.0
HKD1_k127_5046820_8 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000002854 176.0
HKD1_k127_5046820_9 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000006225 155.0
HKD1_k127_5050351_0 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 617.0
HKD1_k127_5050351_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 486.0
HKD1_k127_5050351_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 475.0
HKD1_k127_5050351_3 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 350.0
HKD1_k127_5050351_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
HKD1_k127_5050351_5 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002809 244.0
HKD1_k127_5050351_6 Domain of unknown function (DUF4412) - - - 0.00000000000000000000000000000000000001279 158.0
HKD1_k127_5050351_7 Por secretion system C-terminal sorting domain-containing protein - - - 0.000000000000000000000000000000000009463 158.0
HKD1_k127_5050351_8 amine oxidase K00276 - 1.4.3.21 0.00000000000000000000000000000009386 139.0
HKD1_k127_5050351_9 Protein of unknown function (DUF1646) - - - 0.000000000000000000000000000005438 135.0
HKD1_k127_5078042_0 metalloendopeptidase activity K01283 - 3.4.15.1 1.825e-253 802.0
HKD1_k127_5078042_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.207e-218 697.0
HKD1_k127_5078042_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 377.0
HKD1_k127_5078042_11 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 380.0
HKD1_k127_5078042_12 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 387.0
HKD1_k127_5078042_13 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 330.0
HKD1_k127_5078042_14 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 325.0
HKD1_k127_5078042_15 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 304.0
HKD1_k127_5078042_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 278.0
HKD1_k127_5078042_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002772 273.0
HKD1_k127_5078042_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000923 265.0
HKD1_k127_5078042_19 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000003832 254.0
HKD1_k127_5078042_2 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 2.568e-207 664.0
HKD1_k127_5078042_20 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004603 243.0
HKD1_k127_5078042_21 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002682 249.0
HKD1_k127_5078042_22 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000009717 223.0
HKD1_k127_5078042_23 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000003844 239.0
HKD1_k127_5078042_24 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000000000005637 224.0
HKD1_k127_5078042_25 - - - - 0.000000000000000000000000000000000000000000000000000000000008079 221.0
HKD1_k127_5078042_26 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000000000212 220.0
HKD1_k127_5078042_27 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000003247 224.0
HKD1_k127_5078042_28 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000002607 205.0
HKD1_k127_5078042_29 response regulator - - - 0.0000000000000000000000000000000000000000000000000000003126 200.0
HKD1_k127_5078042_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.641e-199 628.0
HKD1_k127_5078042_30 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000000009754 195.0
HKD1_k127_5078042_31 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000001241 181.0
HKD1_k127_5078042_32 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000006607 196.0
HKD1_k127_5078042_33 DNA-templated transcription, initiation K03088,K07263 - - 0.00000000000000000000000000000000000000001103 163.0
HKD1_k127_5078042_35 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000001627 156.0
HKD1_k127_5078042_36 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000000108 136.0
HKD1_k127_5078042_37 Cytochrome C oxidase, cbb3-type, subunit III K19713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 0.00000000000000000000000000001443 131.0
HKD1_k127_5078042_38 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000009619 124.0
HKD1_k127_5078042_39 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000002512 111.0
HKD1_k127_5078042_4 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 609.0
HKD1_k127_5078042_40 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000004413 91.0
HKD1_k127_5078042_41 - - - - 0.000000391 63.0
HKD1_k127_5078042_42 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000601 57.0
HKD1_k127_5078042_5 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 614.0
HKD1_k127_5078042_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 589.0
HKD1_k127_5078042_7 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 426.0
HKD1_k127_5078042_8 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 432.0
HKD1_k127_5078042_9 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 403.0
HKD1_k127_5112585_0 peptidase K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 617.0
HKD1_k127_5112585_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 556.0
HKD1_k127_5112585_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000002666 182.0
HKD1_k127_5188896_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.802e-227 715.0
HKD1_k127_5188896_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 505.0
HKD1_k127_5188896_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000009512 111.0
HKD1_k127_5188896_3 Putative modulator of DNA gyrase K03568 - - 0.000000000000000007643 98.0
HKD1_k127_5188896_4 CoA carboxylase activity K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.000000000000000268 85.0
HKD1_k127_5201919_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 9.41e-298 929.0
HKD1_k127_5201919_1 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 605.0
HKD1_k127_5201919_10 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000002096 150.0
HKD1_k127_5201919_11 TIGRFAM TonB K03832 - - 0.0000000000000000000000001838 115.0
HKD1_k127_5201919_12 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000002447 106.0
HKD1_k127_5201919_13 biopolymer transport protein K03559,K03560 - - 0.00000000000000000000008855 103.0
HKD1_k127_5201919_14 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000005414 103.0
HKD1_k127_5201919_15 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000007147 100.0
HKD1_k127_5201919_16 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000003511 99.0
HKD1_k127_5201919_17 Outer membrane protein beta-barrel domain - - - 0.00000000005176 72.0
HKD1_k127_5201919_18 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000005486 72.0
HKD1_k127_5201919_19 Tetratricopeptide repeat K09553 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0012505,GO:0031072,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051879,GO:0101031 - 0.00000008123 64.0
HKD1_k127_5201919_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 339.0
HKD1_k127_5201919_20 DNA primase - - - 0.00005724 46.0
HKD1_k127_5201919_21 DNA integration - - - 0.0001415 48.0
HKD1_k127_5201919_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 308.0
HKD1_k127_5201919_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 311.0
HKD1_k127_5201919_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003855 289.0
HKD1_k127_5201919_6 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005562 270.0
HKD1_k127_5201919_7 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
HKD1_k127_5201919_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000005544 236.0
HKD1_k127_5201919_9 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000002098 171.0
HKD1_k127_5267568_0 oligopeptide transporter, OPT family - - - 2.438e-220 703.0
HKD1_k127_5267568_1 ABC transporter transmembrane region K11085 - - 4.958e-205 661.0
HKD1_k127_5267568_10 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.000000003482 59.0
HKD1_k127_5267568_11 - - - - 0.00000002436 66.0
HKD1_k127_5267568_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 421.0
HKD1_k127_5267568_3 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 395.0
HKD1_k127_5267568_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 313.0
HKD1_k127_5267568_5 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000008622 207.0
HKD1_k127_5267568_6 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000001005 147.0
HKD1_k127_5267568_7 Peptidase, M16 K07263 - - 0.000000000000000000003858 98.0
HKD1_k127_5267568_8 Putative porin - - - 0.00000000005636 77.0
HKD1_k127_5267568_9 cellulose binding - - - 0.000000001595 69.0
HKD1_k127_5277833_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.229e-291 906.0
HKD1_k127_5277833_1 Prolyl oligopeptidase K01322 - 3.4.21.26 2.846e-234 747.0
HKD1_k127_5277833_10 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000288 222.0
HKD1_k127_5277833_11 Aspartyl protease - - - 0.000000000000000000000000000000000000000000005176 173.0
HKD1_k127_5277833_12 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000005397 165.0
HKD1_k127_5277833_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000005531 126.0
HKD1_k127_5277833_14 PFAM Glycosyl transferase family 2 - - - 0.0000000000000008522 91.0
HKD1_k127_5277833_15 Protein of unknown function (DUF2959) - - - 0.000000000008893 74.0
HKD1_k127_5277833_2 Involved in the tonB-independent uptake of proteins - - - 1.657e-209 679.0
HKD1_k127_5277833_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 591.0
HKD1_k127_5277833_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 539.0
HKD1_k127_5277833_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 453.0
HKD1_k127_5277833_6 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 399.0
HKD1_k127_5277833_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005919 282.0
HKD1_k127_5277833_8 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001918 258.0
HKD1_k127_5277833_9 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001995 259.0
HKD1_k127_5340170_0 Elongation factor G, domain IV K02355 - - 6.224e-211 676.0
HKD1_k127_5340170_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 419.0
HKD1_k127_5340170_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003831 278.0
HKD1_k127_5340170_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001427 259.0
HKD1_k127_5340170_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000003286 189.0
HKD1_k127_5418155_0 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 422.0
HKD1_k127_5418155_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 380.0
HKD1_k127_5488700_0 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 504.0
HKD1_k127_5488700_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 456.0
HKD1_k127_5488700_2 Amino acid permease K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 412.0
HKD1_k127_5488700_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 406.0
HKD1_k127_5488700_4 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000368 284.0
HKD1_k127_5488700_5 - - - - 0.00000000000000000000000000000000000000000000003523 195.0
HKD1_k127_5488700_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000003291 171.0
HKD1_k127_5488700_7 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00479 - - 0.0000000000000000000000000000000000000006248 156.0
HKD1_k127_5488700_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000008059 110.0
HKD1_k127_5523926_0 class II (D K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 545.0
HKD1_k127_5523926_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 518.0
HKD1_k127_5523926_10 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000003289 249.0
HKD1_k127_5523926_11 Thioredoxin K03671 - - 0.0000000000000000000000000000000004518 149.0
HKD1_k127_5523926_12 Probably functions as a manganese efflux pump - - - 0.000000000000000000241 104.0
HKD1_k127_5523926_13 Pfam Cation efflux - - - 0.0000000000001163 79.0
HKD1_k127_5523926_2 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 517.0
HKD1_k127_5523926_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 401.0
HKD1_k127_5523926_4 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 351.0
HKD1_k127_5523926_5 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 318.0
HKD1_k127_5523926_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004341 280.0
HKD1_k127_5523926_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003097 258.0
HKD1_k127_5523926_8 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000005091 245.0
HKD1_k127_5523926_9 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000159 232.0
HKD1_k127_5561238_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 506.0
HKD1_k127_5561238_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000005241 254.0
HKD1_k127_5561238_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000001815 121.0
HKD1_k127_5628282_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 328.0
HKD1_k127_5628282_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 332.0
HKD1_k127_5628282_10 Competence protein - - - 0.000000000000000000000000000284 124.0
HKD1_k127_5628282_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000002128 128.0
HKD1_k127_5628282_12 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000001315 98.0
HKD1_k127_5628282_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000001756 96.0
HKD1_k127_5628282_14 Glycosyl transferase, family 2 - - - 0.0000000000000006137 93.0
HKD1_k127_5628282_15 Helix-turn-helix - - - 0.000000004019 64.0
HKD1_k127_5628282_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00003914 58.0
HKD1_k127_5628282_17 Transcriptional regulator - - - 0.00005308 54.0
HKD1_k127_5628282_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 302.0
HKD1_k127_5628282_3 proline dehydrogenase activity K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005434 294.0
HKD1_k127_5628282_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005085 267.0
HKD1_k127_5628282_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
HKD1_k127_5628282_6 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000209 164.0
HKD1_k127_5628282_7 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000004169 169.0
HKD1_k127_5628282_8 Transport permease protein K09690 - - 0.000000000000000000000000000000002813 139.0
HKD1_k127_5628282_9 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000009839 127.0
HKD1_k127_5920911_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 531.0
HKD1_k127_5920911_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HKD1_k127_5920911_2 Transport permease protein - - - 0.0000000000000005968 92.0
HKD1_k127_5926898_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 348.0
HKD1_k127_5926898_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000001762 58.0
HKD1_k127_6078550_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 466.0
HKD1_k127_6078550_1 Glycosyl hydrolases family 32 N-terminal domain K01193 - 3.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 330.0
HKD1_k127_6078550_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003325 250.0
HKD1_k127_6078550_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000028 226.0
HKD1_k127_6078550_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000008313 190.0
HKD1_k127_6090263_0 Protein of unknown function (DUF1349) K09702 - - 0.000000000000000000000000000000000000000000000000000000000000856 216.0
HKD1_k127_6090263_1 O-methyltransferase activity - - - 0.00000000000000000000000001012 119.0
HKD1_k127_6095944_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.013e-203 666.0
HKD1_k127_6095944_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 536.0
HKD1_k127_6095944_10 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000003938 249.0
HKD1_k127_6095944_11 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000002836 248.0
HKD1_k127_6095944_12 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000004965 234.0
HKD1_k127_6095944_13 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000007204 228.0
HKD1_k127_6095944_14 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000002408 222.0
HKD1_k127_6095944_15 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000002523 222.0
HKD1_k127_6095944_16 general stress protein 26 - - - 0.00000000000000000000000000000000000000000000000001107 192.0
HKD1_k127_6095944_17 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000000000000000000000001839 192.0
HKD1_k127_6095944_18 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000004331 185.0
HKD1_k127_6095944_19 FAD binding domain - - - 0.0000000000000000000000000000000000000001766 170.0
HKD1_k127_6095944_2 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 472.0
HKD1_k127_6095944_20 Low affinity iron permease - - - 0.0000000000000000000000000000000000000009343 163.0
HKD1_k127_6095944_21 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000003494 156.0
HKD1_k127_6095944_22 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000001189 135.0
HKD1_k127_6095944_23 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000001626 124.0
HKD1_k127_6095944_24 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000001127 130.0
HKD1_k127_6095944_25 Sigma-70 region 2 K03088 - - 0.000000000000000000000001435 113.0
HKD1_k127_6095944_26 Methyltransferase domain - - - 0.000000000000000000003344 102.0
HKD1_k127_6095944_27 Predicted membrane protein (DUF2231) - - - 0.0000000000000000004216 98.0
HKD1_k127_6095944_28 Regulatory protein, FmdB - - - 0.000000000000004645 89.0
HKD1_k127_6095944_29 BON domain K04065 - - 0.00000009797 64.0
HKD1_k127_6095944_3 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 453.0
HKD1_k127_6095944_30 Serine aminopeptidase, S33 - - - 0.00003155 57.0
HKD1_k127_6095944_31 Protein of unknown function (DUF1328) - - - 0.00005153 47.0
HKD1_k127_6095944_4 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 348.0
HKD1_k127_6095944_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 284.0
HKD1_k127_6095944_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001252 271.0
HKD1_k127_6095944_7 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004689 278.0
HKD1_k127_6095944_8 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002964 251.0
HKD1_k127_6095944_9 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003353 264.0
HKD1_k127_6133510_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 4.46e-301 940.0
HKD1_k127_6133510_1 HI0933-like protein K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 608.0
HKD1_k127_6133510_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 361.0
HKD1_k127_6133510_3 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000005926 221.0
HKD1_k127_6133510_4 Uncharacterized conserved protein (DUF2075) K09384 - - 0.000000000000000000000000000000000000000000000001799 178.0
HKD1_k127_6133510_5 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000002161 183.0
HKD1_k127_6133510_7 - - - - 0.000004674 53.0
HKD1_k127_6133510_8 DinB family - - - 0.000009641 54.0
HKD1_k127_6167701_0 Amidohydrolase family - - - 6.3e-223 705.0
HKD1_k127_6167701_1 Amino acid permease - - - 4.986e-218 701.0
HKD1_k127_6167701_10 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000001356 228.0
HKD1_k127_6167701_11 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000212 232.0
HKD1_k127_6167701_12 Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
HKD1_k127_6167701_13 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000001481 215.0
HKD1_k127_6167701_14 response regulator, receiver K07667 - - 0.000000000000000000000000000000000000000000000000000003868 214.0
HKD1_k127_6167701_15 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000001296 214.0
HKD1_k127_6167701_16 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000002954 188.0
HKD1_k127_6167701_17 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000004182 184.0
HKD1_k127_6167701_18 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000007924 160.0
HKD1_k127_6167701_19 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000007714 169.0
HKD1_k127_6167701_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 572.0
HKD1_k127_6167701_20 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000009462 154.0
HKD1_k127_6167701_21 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000725 162.0
HKD1_k127_6167701_22 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000004827 159.0
HKD1_k127_6167701_23 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000003533 155.0
HKD1_k127_6167701_24 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000003226 128.0
HKD1_k127_6167701_25 CBS domain - - - 0.00000000000000000000005913 104.0
HKD1_k127_6167701_26 PQQ enzyme repeat - - - 0.000000000000000000001353 111.0
HKD1_k127_6167701_28 Belongs to the peptidase S8 family K11016 - - 0.000000000000000009677 99.0
HKD1_k127_6167701_29 Cupredoxin-like domain - - - 0.000000000000001629 81.0
HKD1_k127_6167701_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 587.0
HKD1_k127_6167701_30 Copper binding proteins, plastocyanin/azurin family - - - 0.00000008204 61.0
HKD1_k127_6167701_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 565.0
HKD1_k127_6167701_5 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 481.0
HKD1_k127_6167701_6 N,N-dimethylaniline monooxygenase activity K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 477.0
HKD1_k127_6167701_7 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 438.0
HKD1_k127_6167701_8 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 428.0
HKD1_k127_6167701_9 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 344.0
HKD1_k127_6190887_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 356.0
HKD1_k127_6190887_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 313.0
HKD1_k127_6190887_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000003411 157.0
HKD1_k127_6190887_3 pfam mofrl K11529 - 2.7.1.165 0.00000000000000000000000001185 116.0
HKD1_k127_6221464_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 535.0
HKD1_k127_6221464_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 406.0
HKD1_k127_6221464_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0003888 47.0
HKD1_k127_6221464_11 Domain of unknown function (DUF4149) - - - 0.0009375 51.0
HKD1_k127_6221464_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 312.0
HKD1_k127_6221464_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000583 226.0
HKD1_k127_6221464_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000003157 227.0
HKD1_k127_6221464_5 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000001279 192.0
HKD1_k127_6221464_6 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000003079 147.0
HKD1_k127_6221464_7 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000005304 132.0
HKD1_k127_6221464_8 Putative Fe-S cluster K00380 - 1.8.1.2 0.000000000000000000009408 100.0
HKD1_k127_6221464_9 - - - - 0.000000001001 72.0
HKD1_k127_6237152_0 Belongs to the peptidase M16 family K07263 - - 0.0 1038.0
HKD1_k127_6237152_1 Sortilin, neurotensin receptor 3, - - - 2.673e-263 861.0
HKD1_k127_6237152_10 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001166 269.0
HKD1_k127_6237152_11 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000178 192.0
HKD1_k127_6237152_12 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000003405 149.0
HKD1_k127_6237152_13 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000001151 138.0
HKD1_k127_6237152_14 Carbohydrate binding domain - - - 0.000000000000000000000000000003359 139.0
HKD1_k127_6237152_15 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000007535 122.0
HKD1_k127_6237152_16 Chromate resistance exported protein - - - 0.000000000000000000000001035 119.0
HKD1_k127_6237152_17 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000004355 107.0
HKD1_k127_6237152_18 polysaccharide deacetylase K15531 - 3.2.1.156 0.000000000006261 79.0
HKD1_k127_6237152_19 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.00000000003403 64.0
HKD1_k127_6237152_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 1.937e-260 820.0
HKD1_k127_6237152_20 ketosteroid isomerase - - - 0.0001013 51.0
HKD1_k127_6237152_21 FeoA K04758 - - 0.0002362 54.0
HKD1_k127_6237152_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.512e-204 655.0
HKD1_k127_6237152_4 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 1.422e-201 654.0
HKD1_k127_6237152_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 619.0
HKD1_k127_6237152_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 470.0
HKD1_k127_6237152_7 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 492.0
HKD1_k127_6237152_8 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 340.0
HKD1_k127_6237152_9 Zn-dependent protease contains TPR repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 308.0
HKD1_k127_6247392_0 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 572.0
HKD1_k127_6247392_1 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 342.0
HKD1_k127_6247392_2 Winged helix-turn helix K07497 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 313.0
HKD1_k127_6247392_3 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000001122 140.0
HKD1_k127_6268950_0 Prolyl oligopeptidase - - - 2.435e-254 825.0
HKD1_k127_6268950_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 6.921e-211 673.0
HKD1_k127_6268950_10 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 369.0
HKD1_k127_6268950_12 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 323.0
HKD1_k127_6268950_13 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003569 260.0
HKD1_k127_6268950_14 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000002988 259.0
HKD1_k127_6268950_15 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10036 - - 0.000000000000000000000000000000000000000000000000000000000000003791 247.0
HKD1_k127_6268950_16 SIS domain K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000183 233.0
HKD1_k127_6268950_17 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000007178 240.0
HKD1_k127_6268950_18 amine oxidase K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000000000000008535 224.0
HKD1_k127_6268950_19 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000159 207.0
HKD1_k127_6268950_2 imidazolonepropionase activity K01443 - 3.5.1.25 3.337e-202 662.0
HKD1_k127_6268950_20 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000005269 221.0
HKD1_k127_6268950_21 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000000000001604 202.0
HKD1_k127_6268950_22 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000003102 202.0
HKD1_k127_6268950_23 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.000000000000000000000000000000000000000000004333 183.0
HKD1_k127_6268950_24 EVE domain - - - 0.00000000000000000000000000000000000000002369 156.0
HKD1_k127_6268950_25 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.00000000000000000000000000000000000000154 158.0
HKD1_k127_6268950_26 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000197 164.0
HKD1_k127_6268950_27 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000001457 162.0
HKD1_k127_6268950_28 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000002215 142.0
HKD1_k127_6268950_29 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000104 151.0
HKD1_k127_6268950_3 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 617.0
HKD1_k127_6268950_30 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000989 118.0
HKD1_k127_6268950_31 YCII-related domain - - - 0.00000000000000000000000804 111.0
HKD1_k127_6268950_32 Protein of unknown function (DUF2911) - - - 0.0000000000000000001076 98.0
HKD1_k127_6268950_33 Transcriptional regulator - - - 0.0000000000000000008156 101.0
HKD1_k127_6268950_34 - - - - 0.000000000001769 74.0
HKD1_k127_6268950_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 588.0
HKD1_k127_6268950_5 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 512.0
HKD1_k127_6268950_6 PFAM DAHP synthetase I KDSA K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 452.0
HKD1_k127_6268950_7 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 444.0
HKD1_k127_6268950_8 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 431.0
HKD1_k127_6268950_9 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 352.0
HKD1_k127_6291897_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000002285 262.0
HKD1_k127_6291897_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000002966 185.0
HKD1_k127_6291897_2 - - - - 0.00000000000000000000000000000004183 143.0
HKD1_k127_6291897_3 - - - - 0.00000000000000000000000001038 121.0
HKD1_k127_6291897_4 Protein of unknown function (DUF4230) - - - 0.00000000002206 73.0
HKD1_k127_6424414_0 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 415.0
HKD1_k127_6424414_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 392.0
HKD1_k127_6424414_10 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000000001541 78.0
HKD1_k127_6424414_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 386.0
HKD1_k127_6424414_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 348.0
HKD1_k127_6424414_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002711 284.0
HKD1_k127_6424414_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009135 268.0
HKD1_k127_6424414_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000004212 224.0
HKD1_k127_6424414_7 CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000000000000000000000000000004586 233.0
HKD1_k127_6424414_8 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 - - 0.0000000000000000000000000000000000000000000000000000781 211.0
HKD1_k127_6424414_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000001506 104.0
HKD1_k127_6438401_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 464.0
HKD1_k127_6438401_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 419.0
HKD1_k127_6438401_10 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000002867 131.0
HKD1_k127_6438401_11 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000002461 121.0
HKD1_k127_6438401_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000001842 122.0
HKD1_k127_6438401_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000005415 108.0
HKD1_k127_6438401_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 392.0
HKD1_k127_6438401_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000913 66.0
HKD1_k127_6438401_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 338.0
HKD1_k127_6438401_4 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003585 271.0
HKD1_k127_6438401_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
HKD1_k127_6438401_6 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000004889 187.0
HKD1_k127_6438401_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000002208 181.0
HKD1_k127_6438401_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000006429 161.0
HKD1_k127_6438401_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.0000000000000000000000000000000001504 135.0
HKD1_k127_6440611_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 604.0
HKD1_k127_6440611_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 527.0
HKD1_k127_6440611_10 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 307.0
HKD1_k127_6440611_11 Domain of unknown function (DUF4331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 322.0
HKD1_k127_6440611_12 ABC transporter K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007485 270.0
HKD1_k127_6440611_13 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004479 281.0
HKD1_k127_6440611_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000001315 250.0
HKD1_k127_6440611_15 Calx-beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000089 243.0
HKD1_k127_6440611_16 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000001055 244.0
HKD1_k127_6440611_17 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000000000006576 226.0
HKD1_k127_6440611_18 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000000003409 199.0
HKD1_k127_6440611_19 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000000000000000000000000000000000000000000000005785 208.0
HKD1_k127_6440611_2 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 501.0
HKD1_k127_6440611_20 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000388 154.0
HKD1_k127_6440611_21 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000001437 162.0
HKD1_k127_6440611_22 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000006745 157.0
HKD1_k127_6440611_23 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000005395 131.0
HKD1_k127_6440611_24 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000025 124.0
HKD1_k127_6440611_25 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000397 136.0
HKD1_k127_6440611_26 endo-1,4-beta-xylanase activity - GO:0005575,GO:0005576 - 0.00000000000000000000002135 116.0
HKD1_k127_6440611_27 Alpha beta - - - 0.000000000000000000001802 106.0
HKD1_k127_6440611_28 Smr domain - - - 0.000000000000000000009614 101.0
HKD1_k127_6440611_29 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0000000000000000001184 102.0
HKD1_k127_6440611_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 481.0
HKD1_k127_6440611_30 Iron-binding zinc finger CDGSH type K05710 - - 0.0000000000000000007872 89.0
HKD1_k127_6440611_31 Anti-sigma-K factor rskA - - - 0.0000000000000001719 89.0
HKD1_k127_6440611_32 - - - - 0.0000000002006 66.0
HKD1_k127_6440611_33 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000435 64.0
HKD1_k127_6440611_34 OsmC-like protein - - - 0.0000009395 59.0
HKD1_k127_6440611_35 Immune inhibitor A peptidase M6 - - - 0.0001222 56.0
HKD1_k127_6440611_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 476.0
HKD1_k127_6440611_5 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 482.0
HKD1_k127_6440611_6 PFAM Na-Ca exchanger integrin-beta4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 456.0
HKD1_k127_6440611_7 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 378.0
HKD1_k127_6440611_8 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 340.0
HKD1_k127_6440611_9 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 313.0
HKD1_k127_6442022_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 463.0
HKD1_k127_6442022_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000001454 162.0
HKD1_k127_6442022_2 Pfam Methyltransferase - - - 0.000000000000005035 89.0
HKD1_k127_6442022_3 cellulose binding - - - 0.00000003345 65.0
HKD1_k127_6442022_4 glycosyl transferase family 2 K07011 - - 0.0009448 50.0
HKD1_k127_6450966_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1277.0
HKD1_k127_6450966_1 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 331.0
HKD1_k127_6450966_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 309.0
HKD1_k127_6450966_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006332 302.0
HKD1_k127_6450966_4 cytochrome C assembly protein - - - 0.00000000000000003257 92.0
HKD1_k127_6450966_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000004187 59.0
HKD1_k127_6505310_0 AAA ATPase domain - - - 5.813e-278 887.0
HKD1_k127_6505310_1 ABC transporter K06020 - 3.6.3.25 3.798e-262 817.0
HKD1_k127_6505310_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000001347 202.0
HKD1_k127_6505310_11 Protein of unknown function (DUF983) - - - 0.0000000000000001246 85.0
HKD1_k127_6505310_12 Protein of unknown function, DUF481 K07283 - - 0.0000000000428 75.0
HKD1_k127_6505310_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.346e-221 703.0
HKD1_k127_6505310_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005869 279.0
HKD1_k127_6505310_4 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004112 264.0
HKD1_k127_6505310_5 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
HKD1_k127_6505310_6 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001399 261.0
HKD1_k127_6505310_7 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000003907 246.0
HKD1_k127_6505310_8 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000003886 232.0
HKD1_k127_6505310_9 antibiotic catabolic process - - - 0.000000000000000000000000000000000000000000000000000000001398 228.0
HKD1_k127_665142_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.002e-206 654.0
HKD1_k127_665142_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 594.0
HKD1_k127_665142_10 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000001156 121.0
HKD1_k127_665142_11 Biogenesis protein - - - 0.0000000000000000000000002329 120.0
HKD1_k127_665142_12 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000132 81.0
HKD1_k127_665142_13 - - - - 0.0000000003717 71.0
HKD1_k127_665142_2 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 475.0
HKD1_k127_665142_3 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 469.0
HKD1_k127_665142_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 332.0
HKD1_k127_665142_5 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000001853 243.0
HKD1_k127_665142_7 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000002071 164.0
HKD1_k127_665142_8 Rhodanese-like domain - - - 0.000000000000000000000000000000002165 143.0
HKD1_k127_665142_9 carbon dioxide binding K04653,K04654 - - 0.000000000000000000000000003038 128.0
HKD1_k127_6686566_0 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 465.0
HKD1_k127_6686566_1 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000005126 195.0
HKD1_k127_6686566_2 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000001658 201.0
HKD1_k127_6686566_3 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000005688 190.0
HKD1_k127_6686566_4 - - - - 0.0000000000000000000000000000000000000000000001048 188.0
HKD1_k127_6686566_5 transglycosylase K08309 - - 0.00000000000000000000000000000000004011 155.0
HKD1_k127_6686566_6 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000004168 120.0
HKD1_k127_6686566_7 nuclear chromosome segregation - - - 0.000000000000000000000107 111.0
HKD1_k127_6686566_8 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000003304 91.0
HKD1_k127_6717248_0 Acetamidase formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 336.0
HKD1_k127_6717248_1 PFAM Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007785 253.0
HKD1_k127_6717248_2 thyroxine 5'-deiodinase activity K01562 GO:0003674,GO:0003824,GO:0004800,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008430,GO:0009987,GO:0010817,GO:0016020,GO:0016491,GO:0018958,GO:0042403,GO:0042445,GO:0044237,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901360,GO:1901564,GO:1901615 1.21.99.4 0.00000000000000000000000000003765 121.0
HKD1_k127_6717248_3 Predicted membrane protein (DUF2127) - - - 0.00000002308 63.0
HKD1_k127_6717248_4 6-phosphogluconolactonase activity - - - 0.0000001614 58.0
HKD1_k127_6717248_5 Iodothyronine deiodinase - - - 0.00004342 49.0
HKD1_k127_6717248_6 cellulase activity - - - 0.000248 54.0
HKD1_k127_690652_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 561.0
HKD1_k127_690652_1 Aminotransferase class-III K09251 - 2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 543.0
HKD1_k127_690652_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000002451 147.0
HKD1_k127_690652_11 - - - - 0.000000000000000000000000000000000002637 143.0
HKD1_k127_690652_12 - - - - 0.0000000000000000000000000000005294 125.0
HKD1_k127_690652_13 Phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000558 111.0
HKD1_k127_690652_14 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.00000000000000000004867 100.0
HKD1_k127_690652_15 YXWGXW repeat (2 copies) - - - 0.000000000000000007161 99.0
HKD1_k127_690652_2 Peptidase family M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 499.0
HKD1_k127_690652_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 486.0
HKD1_k127_690652_4 amino acid K03293,K16238,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 455.0
HKD1_k127_690652_5 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 443.0
HKD1_k127_690652_6 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 354.0
HKD1_k127_690652_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 362.0
HKD1_k127_690652_8 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001029 267.0
HKD1_k127_690652_9 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000009135 177.0
HKD1_k127_6952631_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.314e-288 911.0
HKD1_k127_6952631_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 3.257e-249 780.0
HKD1_k127_6952631_10 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001273 252.0
HKD1_k127_6952631_11 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001349 211.0
HKD1_k127_6952631_12 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000002625 205.0
HKD1_k127_6952631_13 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000006679 201.0
HKD1_k127_6952631_14 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000000000006066 164.0
HKD1_k127_6952631_15 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000001416 158.0
HKD1_k127_6952631_16 Acetyl propionyl-CoA carboxylase alpha subunit K01968 - 6.4.1.4 0.00000000000000000006644 105.0
HKD1_k127_6952631_17 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000001136 98.0
HKD1_k127_6952631_18 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000002592 90.0
HKD1_k127_6952631_19 Ferric siderophore transporter, periplasmic energy transduction protein TonB K03832 - - 0.00000000005461 76.0
HKD1_k127_6952631_2 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 468.0
HKD1_k127_6952631_3 Aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 379.0
HKD1_k127_6952631_4 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 351.0
HKD1_k127_6952631_5 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 334.0
HKD1_k127_6952631_6 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 345.0
HKD1_k127_6952631_7 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 349.0
HKD1_k127_6952631_8 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 320.0
HKD1_k127_6952631_9 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 311.0
HKD1_k127_6975679_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 529.0
HKD1_k127_6975679_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 492.0
HKD1_k127_6975679_10 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 312.0
HKD1_k127_6975679_11 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 305.0
HKD1_k127_6975679_12 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 312.0
HKD1_k127_6975679_13 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 292.0
HKD1_k127_6975679_14 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000687 286.0
HKD1_k127_6975679_15 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000006015 242.0
HKD1_k127_6975679_16 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000004999 229.0
HKD1_k127_6975679_17 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000005868 209.0
HKD1_k127_6975679_18 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000005837 186.0
HKD1_k127_6975679_19 NmrA-like family - - - 0.000000000000000000000000000000000000000000168 182.0
HKD1_k127_6975679_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 483.0
HKD1_k127_6975679_20 transglycosylase K08309 - - 0.000000000000000000000000000000000011 155.0
HKD1_k127_6975679_21 NUDIX domain - - - 0.000000000000000000000000000000000217 139.0
HKD1_k127_6975679_22 peptidyl-tyrosine sulfation - - - 0.0000002673 65.0
HKD1_k127_6975679_24 Sporulation related domain - - - 0.00007821 53.0
HKD1_k127_6975679_3 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 428.0
HKD1_k127_6975679_4 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 406.0
HKD1_k127_6975679_5 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 421.0
HKD1_k127_6975679_6 Repeat of Unknown Function (DUF347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 377.0
HKD1_k127_6975679_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 363.0
HKD1_k127_6975679_8 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 329.0
HKD1_k127_6975679_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 323.0
HKD1_k127_7051506_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.205e-259 812.0
HKD1_k127_7051506_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 5.996e-232 734.0
HKD1_k127_7051506_10 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 359.0
HKD1_k127_7051506_11 Chalcone and stilbene synthases, N-terminal domain K16167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004723 276.0
HKD1_k127_7051506_12 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004583 260.0
HKD1_k127_7051506_13 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000001078 257.0
HKD1_k127_7051506_14 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000001454 248.0
HKD1_k127_7051506_15 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001026 236.0
HKD1_k127_7051506_16 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000009374 226.0
HKD1_k127_7051506_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000003199 239.0
HKD1_k127_7051506_18 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000002564 213.0
HKD1_k127_7051506_19 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000007975 217.0
HKD1_k127_7051506_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.371e-194 654.0
HKD1_k127_7051506_20 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000001275 218.0
HKD1_k127_7051506_21 response to pH - - - 0.000000000000000000000000000000000000000000000006799 182.0
HKD1_k127_7051506_22 Histidine kinase - - - 0.0000000000000000000000000000000000000000000003309 182.0
HKD1_k127_7051506_23 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000001316 150.0
HKD1_k127_7051506_24 DinB family - - - 0.00000000000000000000000000000000003219 141.0
HKD1_k127_7051506_25 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000003137 145.0
HKD1_k127_7051506_26 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000001116 128.0
HKD1_k127_7051506_27 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000003132 130.0
HKD1_k127_7051506_28 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000003678 117.0
HKD1_k127_7051506_29 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000005996 121.0
HKD1_k127_7051506_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 571.0
HKD1_k127_7051506_31 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000004008 105.0
HKD1_k127_7051506_32 Thioesterase-like superfamily K07107 - - 0.00000000000000007695 94.0
HKD1_k127_7051506_33 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000004386 85.0
HKD1_k127_7051506_34 acyl carrier protein K02078 - - 0.00000000001207 69.0
HKD1_k127_7051506_35 PFAM YbbR-like protein - - - 0.0000000003256 73.0
HKD1_k127_7051506_37 Integral membrane sensor hybrid histidine kinase - - - 0.00000246 60.0
HKD1_k127_7051506_38 Forkhead associated domain - - - 0.00009826 54.0
HKD1_k127_7051506_39 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0005282 52.0
HKD1_k127_7051506_4 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 567.0
HKD1_k127_7051506_5 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 525.0
HKD1_k127_7051506_6 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 522.0
HKD1_k127_7051506_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 461.0
HKD1_k127_7051506_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 367.0
HKD1_k127_7051506_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 353.0
HKD1_k127_7064137_0 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002498 269.0
HKD1_k127_7064137_1 Zinc metalloprotease (Elastase) K01400 - 3.4.24.28 0.0000000000000000000000000000000006671 142.0
HKD1_k127_7064137_2 - - - - 0.000000000003877 78.0
HKD1_k127_7064137_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000006321 63.0
HKD1_k127_7064137_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000002747 55.0
HKD1_k127_7083436_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 4.074e-236 751.0
HKD1_k127_7083436_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 4.569e-212 677.0
HKD1_k127_7083436_10 LuxR family transcriptional regulator K03424 - - 0.000000000000000000000000000000000000000000000000000000006013 208.0
HKD1_k127_7083436_11 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000006176 188.0
HKD1_k127_7083436_12 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000007023 183.0
HKD1_k127_7083436_13 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000002701 183.0
HKD1_k127_7083436_14 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000006097 143.0
HKD1_k127_7083436_15 Methyltransferase domain - - - 0.00000000000000000000000000000000001579 149.0
HKD1_k127_7083436_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000004704 123.0
HKD1_k127_7083436_17 CoA binding domain K06929 - - 0.000000000000000000000000000002073 138.0
HKD1_k127_7083436_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000001171 108.0
HKD1_k127_7083436_19 Zincin-like metallopeptidase - - - 0.00000000000000000000004061 112.0
HKD1_k127_7083436_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.474e-210 686.0
HKD1_k127_7083436_20 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000514 96.0
HKD1_k127_7083436_21 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000009174 86.0
HKD1_k127_7083436_22 Protein of unknown function (DUF503) K09764 - - 0.000000000001173 72.0
HKD1_k127_7083436_3 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 486.0
HKD1_k127_7083436_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 378.0
HKD1_k127_7083436_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 355.0
HKD1_k127_7083436_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 344.0
HKD1_k127_7083436_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 316.0
HKD1_k127_7083436_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 329.0
HKD1_k127_7083436_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000002291 220.0
HKD1_k127_7111513_0 Sulfatase K01130 - 3.1.6.1 5.6e-322 992.0
HKD1_k127_7111513_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 2.257e-267 864.0
HKD1_k127_7111513_10 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 381.0
HKD1_k127_7111513_11 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 370.0
HKD1_k127_7111513_12 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 343.0
HKD1_k127_7111513_13 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 339.0
HKD1_k127_7111513_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000255 261.0
HKD1_k127_7111513_15 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005808 266.0
HKD1_k127_7111513_16 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000009143 236.0
HKD1_k127_7111513_17 spore germination - - - 0.000000000000000000000000000000000000000000000000000006103 206.0
HKD1_k127_7111513_18 peptidase - - - 0.000000000000000000000000000000000000000000000000000006951 215.0
HKD1_k127_7111513_19 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000003994 212.0
HKD1_k127_7111513_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.698e-261 834.0
HKD1_k127_7111513_20 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000177 197.0
HKD1_k127_7111513_21 Domain of unknown function (DUF4405) - - - 0.0000000000000000000000000000000000000000000000001718 198.0
HKD1_k127_7111513_22 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000002062 141.0
HKD1_k127_7111513_23 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000002697 134.0
HKD1_k127_7111513_24 regulation of translation K03530 - - 0.0000000000000000000000000000001024 134.0
HKD1_k127_7111513_25 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000001717 133.0
HKD1_k127_7111513_26 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000001459 130.0
HKD1_k127_7111513_27 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.0000000000000000000000000007779 125.0
HKD1_k127_7111513_28 Thioesterase superfamily - - - 0.0000000000000000000000002923 111.0
HKD1_k127_7111513_29 cheY-homologous receiver domain - - - 0.0000000000000000000000003186 111.0
HKD1_k127_7111513_3 PFAM sulfatase K01130 - 3.1.6.1 1.155e-221 695.0
HKD1_k127_7111513_30 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000002281 93.0
HKD1_k127_7111513_31 peptidyl-tyrosine sulfation - - - 0.0000000001454 70.0
HKD1_k127_7111513_32 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000004239 55.0
HKD1_k127_7111513_33 SprT-like family - - - 0.0001326 51.0
HKD1_k127_7111513_34 Pilus assembly protein PilZ K02676 - - 0.0005669 51.0
HKD1_k127_7111513_4 Involved in the tonB-independent uptake of proteins - - - 1.1e-216 721.0
HKD1_k127_7111513_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.512e-213 679.0
HKD1_k127_7111513_6 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 569.0
HKD1_k127_7111513_7 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 469.0
HKD1_k127_7111513_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 463.0
HKD1_k127_7111513_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 411.0
HKD1_k127_7118913_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1253.0
HKD1_k127_7118913_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 379.0
HKD1_k127_7118913_10 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000001453 105.0
HKD1_k127_7118913_11 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000852 109.0
HKD1_k127_7118913_12 PFAM secretion protein HlyD K02005 - - 0.000000000000000000003422 105.0
HKD1_k127_7118913_13 Transcriptional regulator - - - 0.0000000000000000002291 94.0
HKD1_k127_7118913_14 Membrane - - - 0.00000000000000006851 96.0
HKD1_k127_7118913_15 Bacterial regulatory proteins, tetR family - - - 0.0000000000000002757 87.0
HKD1_k127_7118913_16 - - - - 0.00005235 51.0
HKD1_k127_7118913_2 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 348.0
HKD1_k127_7118913_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 314.0
HKD1_k127_7118913_4 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
HKD1_k127_7118913_5 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001276 263.0
HKD1_k127_7118913_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000002923 239.0
HKD1_k127_7118913_7 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000001759 194.0
HKD1_k127_7118913_8 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000004041 177.0
HKD1_k127_7118913_9 ggdef domain - - - 0.000000000000000000000000000000002508 143.0
HKD1_k127_7135902_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.126e-194 639.0
HKD1_k127_7135902_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 484.0
HKD1_k127_7135902_2 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 344.0
HKD1_k127_7135902_3 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 343.0
HKD1_k127_7135902_4 Amino acid permease K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 328.0
HKD1_k127_7135902_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 348.0
HKD1_k127_7135902_6 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000003529 109.0
HKD1_k127_7159729_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 510.0
HKD1_k127_7159729_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000003303 171.0
HKD1_k127_7159729_2 - - - - 0.000000000000000000000000000002509 132.0
HKD1_k127_7159729_3 Adenylate cyclase - - - 0.00000000000000000003041 100.0
HKD1_k127_7159729_4 PFAM peptidase M28 - - - 0.00000000009771 70.0
HKD1_k127_7168258_0 Oligoendopeptidase f - - - 2.182e-228 722.0
HKD1_k127_7168258_1 Peptidase family M1 domain K01256,K08776 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 457.0
HKD1_k127_7177708_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 484.0
HKD1_k127_7177708_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 490.0
HKD1_k127_7177708_10 DNA-sulfur modification-associated - - - 0.000001872 60.0
HKD1_k127_7177708_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 346.0
HKD1_k127_7177708_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000003237 231.0
HKD1_k127_7177708_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000001125 209.0
HKD1_k127_7177708_5 PFAM EAL domain - - - 0.000000000000000000000000000111 129.0
HKD1_k127_7177708_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000003415 114.0
HKD1_k127_7177708_7 S4 RNA-binding domain K04762 - - 0.0000000000000002466 84.0
HKD1_k127_7177708_8 - - - - 0.0000000000000004381 83.0
HKD1_k127_7177708_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000004586 84.0
HKD1_k127_7183662_0 A G-specific K03575 - - 0.0000000000000000000000000000000000003657 148.0
HKD1_k127_7183662_1 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000000000000005485 139.0
HKD1_k127_7194507_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 593.0
HKD1_k127_7194507_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 569.0
HKD1_k127_7194507_10 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.0000000000000000000000000004672 119.0
HKD1_k127_7194507_11 DoxX K15977 - - 0.00000000000000000000000009205 111.0
HKD1_k127_7194507_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 472.0
HKD1_k127_7194507_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 323.0
HKD1_k127_7194507_4 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 327.0
HKD1_k127_7194507_5 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003145 263.0
HKD1_k127_7194507_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000002478 239.0
HKD1_k127_7194507_7 Macro domain protein - - - 0.0000000000000000000000000000000000001092 159.0
HKD1_k127_7194507_8 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000000000000001118 150.0
HKD1_k127_7194507_9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000002368 123.0
HKD1_k127_726538_0 N-terminal domain of (some) glycogen debranching enzymes - - - 6.98e-219 732.0
HKD1_k127_726538_1 Glycosyl hydrolases family 15 - - - 1.08e-215 717.0
HKD1_k127_726538_10 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000004609 214.0
HKD1_k127_726538_11 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000005254 223.0
HKD1_k127_726538_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000001314 194.0
HKD1_k127_726538_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000001959 174.0
HKD1_k127_726538_15 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000553 133.0
HKD1_k127_726538_16 cheY-homologous receiver domain - - - 0.0000000000000000000000000000005921 141.0
HKD1_k127_726538_17 YMGG-like Gly-zipper - - - 0.000000000000000000000000000001459 132.0
HKD1_k127_726538_18 Cytochrome c - - - 0.00000000000000000000009534 107.0
HKD1_k127_726538_19 HWE histidine kinase - - - 0.0000000000000000000001238 111.0
HKD1_k127_726538_2 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 557.0
HKD1_k127_726538_20 phosphorelay signal transduction system - - - 0.000000000000000000001019 102.0
HKD1_k127_726538_21 - - - - 0.0000000000000000001395 100.0
HKD1_k127_726538_22 - - - - 0.0000000000000002271 83.0
HKD1_k127_726538_23 - - - - 0.00000000000008793 81.0
HKD1_k127_726538_24 Hemerythrin hhe cation binding - - - 0.000000003335 66.0
HKD1_k127_726538_25 Putative MetA-pathway of phenol degradation - - - 0.0000000479 60.0
HKD1_k127_726538_26 COG0642 Signal transduction histidine kinase - - - 0.0001283 47.0
HKD1_k127_726538_3 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 523.0
HKD1_k127_726538_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 449.0
HKD1_k127_726538_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 453.0
HKD1_k127_726538_6 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 383.0
HKD1_k127_726538_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 359.0
HKD1_k127_726538_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000008054 233.0
HKD1_k127_726538_9 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000001357 222.0
HKD1_k127_731587_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 425.0
HKD1_k127_731587_1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 311.0
HKD1_k127_731587_2 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000002355 225.0
HKD1_k127_731587_3 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000001344 166.0
HKD1_k127_7362376_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 418.0
HKD1_k127_7362376_1 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 354.0
HKD1_k127_7362376_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000001066 211.0
HKD1_k127_7362376_3 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000798 196.0
HKD1_k127_7362376_4 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000003886 190.0
HKD1_k127_7362376_5 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000001035 162.0
HKD1_k127_7362376_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000284 54.0
HKD1_k127_7362376_7 Putative zinc-finger - - - 0.000456 50.0
HKD1_k127_7398138_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 544.0
HKD1_k127_7398138_1 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 549.0
HKD1_k127_7398138_2 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 505.0
HKD1_k127_7398138_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 362.0
HKD1_k127_7398138_4 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 325.0
HKD1_k127_7398138_5 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 297.0
HKD1_k127_7398138_6 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000002068 247.0
HKD1_k127_7398138_7 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000005795 194.0
HKD1_k127_7398138_8 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000004028 158.0
HKD1_k127_7398138_9 - - - - 0.0000000000000000000000003463 109.0
HKD1_k127_7401316_0 Amino acid permease - - - 3.281e-209 672.0
HKD1_k127_7401316_1 PFAM NAD-dependent epimerase dehydratase - - - 1.888e-197 625.0
HKD1_k127_7401316_10 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 382.0
HKD1_k127_7401316_11 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 316.0
HKD1_k127_7401316_12 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000003499 276.0
HKD1_k127_7401316_13 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002673 248.0
HKD1_k127_7401316_14 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000002741 243.0
HKD1_k127_7401316_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000003098 224.0
HKD1_k127_7401316_16 PFAM Glycosyl transferase family 2 K14597 - - 0.00000000000000000000000000000000000000000000000000215 201.0
HKD1_k127_7401316_17 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000003622 195.0
HKD1_k127_7401316_18 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000004127 168.0
HKD1_k127_7401316_19 iron-sulfur cluster assembly K07400 - - 0.000000000000000000000000000000000000000001279 164.0
HKD1_k127_7401316_2 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 582.0
HKD1_k127_7401316_20 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000001192 172.0
HKD1_k127_7401316_21 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000002352 129.0
HKD1_k127_7401316_22 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000004315 139.0
HKD1_k127_7401316_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000003554 128.0
HKD1_k127_7401316_24 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000002242 110.0
HKD1_k127_7401316_25 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000134 107.0
HKD1_k127_7401316_26 Protein of unknown function (DUF962) - - - 0.0000000000000000001677 93.0
HKD1_k127_7401316_27 - - - - 0.0000000000000000141 98.0
HKD1_k127_7401316_28 histidine kinase A domain protein - - - 0.000000000008742 67.0
HKD1_k127_7401316_29 Heavy-metal resistance - - - 0.00000000405 70.0
HKD1_k127_7401316_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 569.0
HKD1_k127_7401316_30 mRNA catabolic process K06950 - - 0.00000005132 61.0
HKD1_k127_7401316_31 Belongs to the HesB IscA family K13628 - - 0.0000005564 55.0
HKD1_k127_7401316_32 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.00006856 55.0
HKD1_k127_7401316_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 533.0
HKD1_k127_7401316_5 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 513.0
HKD1_k127_7401316_6 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 521.0
HKD1_k127_7401316_7 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 458.0
HKD1_k127_7401316_8 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 441.0
HKD1_k127_7401316_9 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 404.0
HKD1_k127_7450504_0 ABC transporter transmembrane region K11085 - - 6.804e-210 673.0
HKD1_k127_7450504_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.618e-198 642.0
HKD1_k127_7450504_10 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000005312 273.0
HKD1_k127_7450504_11 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000004866 267.0
HKD1_k127_7450504_12 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000008837 241.0
HKD1_k127_7450504_13 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000007532 249.0
HKD1_k127_7450504_14 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000002199 195.0
HKD1_k127_7450504_15 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000903 188.0
HKD1_k127_7450504_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000006571 183.0
HKD1_k127_7450504_17 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.0000000000000000000000000000000000000000000002472 179.0
HKD1_k127_7450504_18 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000006014 171.0
HKD1_k127_7450504_19 - - - - 0.00000000000000000000000000000000000000001621 173.0
HKD1_k127_7450504_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 561.0
HKD1_k127_7450504_20 photosynthesis - - - 0.000000000000000000000000000000000000007934 162.0
HKD1_k127_7450504_21 Helix-turn-helix domain - - - 0.0000000000000000000000000000000002691 140.0
HKD1_k127_7450504_22 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000008969 138.0
HKD1_k127_7450504_23 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002134 136.0
HKD1_k127_7450504_24 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.000000000000000000000000001204 125.0
HKD1_k127_7450504_27 PFAM Iron permease FTR1 K07243 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000004262 99.0
HKD1_k127_7450504_29 Protein of unknown function (DUF1475) - - - 0.000000000000000003995 98.0
HKD1_k127_7450504_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 424.0
HKD1_k127_7450504_32 Alg9-like mannosyltransferase family K05286 - - 0.00000000007775 74.0
HKD1_k127_7450504_33 desaturase K00507 - 1.14.19.1 0.0000000006939 66.0
HKD1_k127_7450504_34 - - - - 0.000009939 58.0
HKD1_k127_7450504_35 PFAM blue (type 1) copper domain protein - - - 0.00006875 55.0
HKD1_k127_7450504_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 409.0
HKD1_k127_7450504_5 NAD FAD-binding protein K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 394.0
HKD1_k127_7450504_6 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 369.0
HKD1_k127_7450504_7 - K12065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 347.0
HKD1_k127_7450504_8 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 289.0
HKD1_k127_7450504_9 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000004317 286.0
HKD1_k127_7471555_0 Beta-lactamase - - - 5.282e-290 904.0
HKD1_k127_7471555_1 Pyridine nucleotide-disulphide oxidoreductase - - - 2.57e-213 675.0
HKD1_k127_7471555_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 331.0
HKD1_k127_7471555_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 289.0
HKD1_k127_7471555_12 Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000813 280.0
HKD1_k127_7471555_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001167 269.0
HKD1_k127_7471555_14 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003083 267.0
HKD1_k127_7471555_15 membrane - - - 0.000000000000000000000000000000000000000000000000000006651 193.0
HKD1_k127_7471555_16 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000007768 178.0
HKD1_k127_7471555_17 radical SAM domain protein - - - 0.000000000000000000000000000000000000000001676 169.0
HKD1_k127_7471555_18 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000001349 134.0
HKD1_k127_7471555_19 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000007742 111.0
HKD1_k127_7471555_2 heat shock protein binding - - - 1.588e-212 717.0
HKD1_k127_7471555_21 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000001414 90.0
HKD1_k127_7471555_22 Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 K07006,K22343 - 1.14.13.238 0.0000000000006248 72.0
HKD1_k127_7471555_3 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 492.0
HKD1_k127_7471555_4 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 466.0
HKD1_k127_7471555_5 Cytochrome p450 K15468 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 419.0
HKD1_k127_7471555_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 407.0
HKD1_k127_7471555_7 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 411.0
HKD1_k127_7471555_8 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 372.0
HKD1_k127_7471555_9 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 369.0
HKD1_k127_7491007_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 428.0
HKD1_k127_7491007_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 371.0
HKD1_k127_7491007_2 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001937 282.0
HKD1_k127_7491007_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000002526 270.0
HKD1_k127_7491007_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000001239 210.0
HKD1_k127_7491007_5 PFAM ABC-2 type transporter K01992,K09690 - - 0.00000000000000000000000000000000000000000003625 175.0
HKD1_k127_7491007_6 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000005137 123.0
HKD1_k127_7491007_7 Protein of unknown function (DUF1254) - - - 0.00000000000000000000218 97.0
HKD1_k127_7524098_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.71e-202 655.0
HKD1_k127_7524098_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 382.0
HKD1_k127_7524098_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 310.0
HKD1_k127_7524098_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000355 281.0
HKD1_k127_7524098_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000009058 235.0
HKD1_k127_7524098_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000007627 200.0
HKD1_k127_7524098_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000899 165.0
HKD1_k127_7524098_7 Cupredoxin-like domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000001174 145.0
HKD1_k127_7524098_8 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000009401 129.0
HKD1_k127_7528252_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1120.0
HKD1_k127_7528252_1 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 1.357e-320 1002.0
HKD1_k127_7528252_10 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 352.0
HKD1_k127_7528252_11 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 313.0
HKD1_k127_7528252_12 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 313.0
HKD1_k127_7528252_13 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 331.0
HKD1_k127_7528252_14 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 284.0
HKD1_k127_7528252_15 NHL repeat K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003776 314.0
HKD1_k127_7528252_16 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001337 280.0
HKD1_k127_7528252_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004225 288.0
HKD1_k127_7528252_18 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004175 277.0
HKD1_k127_7528252_19 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004493 265.0
HKD1_k127_7528252_2 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 600.0
HKD1_k127_7528252_20 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001225 244.0
HKD1_k127_7528252_21 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002419 231.0
HKD1_k127_7528252_22 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000461 240.0
HKD1_k127_7528252_23 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000001535 228.0
HKD1_k127_7528252_24 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000001347 199.0
HKD1_k127_7528252_25 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000009328 188.0
HKD1_k127_7528252_26 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000003552 153.0
HKD1_k127_7528252_27 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000008008 146.0
HKD1_k127_7528252_28 NHL repeat - - - 0.000000000000000000000000000000001119 153.0
HKD1_k127_7528252_29 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000001808 127.0
HKD1_k127_7528252_3 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 538.0
HKD1_k127_7528252_30 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000003768 109.0
HKD1_k127_7528252_31 Outer membrane efflux protein - - - 0.00000000000000000000002447 115.0
HKD1_k127_7528252_32 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000001483 83.0
HKD1_k127_7528252_33 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000004705 63.0
HKD1_k127_7528252_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002384 61.0
HKD1_k127_7528252_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 563.0
HKD1_k127_7528252_5 PFAM amine oxidase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 427.0
HKD1_k127_7528252_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 424.0
HKD1_k127_7528252_7 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 416.0
HKD1_k127_7528252_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 372.0
HKD1_k127_7528252_9 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 350.0
HKD1_k127_7537821_0 polysaccharide catabolic process K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 363.0
HKD1_k127_7537821_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 343.0
HKD1_k127_7537821_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 305.0
HKD1_k127_7537821_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000001571 187.0
HKD1_k127_7537821_4 cytochrome - - - 0.000000000000000000000000000000000000000007175 167.0
HKD1_k127_7537821_5 Oxidoreductase FAD-binding domain K02613,K07140 - - 0.000000000000000000000000000000000000000007575 169.0
HKD1_k127_7537821_6 MerR, DNA binding - - - 0.00000000000000000000000000005203 122.0
HKD1_k127_7537821_7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000001446 60.0
HKD1_k127_7537821_8 Pfam:DUF1628 - - - 0.00001571 57.0
HKD1_k127_7655720_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 548.0
HKD1_k127_7655720_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 431.0
HKD1_k127_7655720_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000006892 209.0
HKD1_k127_7655720_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000008252 205.0
HKD1_k127_7655720_12 - - - - 0.00000000000000000000000000000000000000000000000002772 188.0
HKD1_k127_7655720_13 PFAM Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000002204 180.0
HKD1_k127_7655720_14 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000000000001573 169.0
HKD1_k127_7655720_15 DinB superfamily - - - 0.000000000000000000000000000000000001721 158.0
HKD1_k127_7655720_16 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000000005662 119.0
HKD1_k127_7655720_17 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000007721 115.0
HKD1_k127_7655720_18 - - - - 0.00000000000000000000000154 116.0
HKD1_k127_7655720_19 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000168 47.0
HKD1_k127_7655720_2 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286,K08641 - 3.4.13.22,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 393.0
HKD1_k127_7655720_3 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 379.0
HKD1_k127_7655720_4 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 343.0
HKD1_k127_7655720_5 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002502 272.0
HKD1_k127_7655720_6 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006521 272.0
HKD1_k127_7655720_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000328 261.0
HKD1_k127_7655720_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003777 235.0
HKD1_k127_7655720_9 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000269 207.0
HKD1_k127_7693713_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 518.0
HKD1_k127_7693713_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 451.0
HKD1_k127_7693713_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000003201 75.0
HKD1_k127_7693713_11 Involved in formation and maintenance of cell shape K03570 - - 0.0000000001853 71.0
HKD1_k127_7693713_2 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 435.0
HKD1_k127_7693713_3 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 416.0
HKD1_k127_7693713_4 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005321 288.0
HKD1_k127_7693713_5 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000009488 263.0
HKD1_k127_7693713_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001019 280.0
HKD1_k127_7693713_7 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000284 255.0
HKD1_k127_7693713_8 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000001004 143.0
HKD1_k127_7693713_9 PFAM FecR protein - - - 0.000000000000000000001187 109.0
HKD1_k127_7753005_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 526.0
HKD1_k127_7753005_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 396.0
HKD1_k127_7753005_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 357.0
HKD1_k127_7753005_3 Rhodanese Homology Domain K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000001399 262.0
HKD1_k127_7753005_4 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000002228 233.0
HKD1_k127_7753005_5 - - - - 0.00000000000000000000000000000000000000007484 166.0
HKD1_k127_7753005_7 Collagen, type IV, alpha 4 K06237 - - 0.00001045 57.0
HKD1_k127_7787952_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.019e-271 851.0
HKD1_k127_7787952_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 573.0
HKD1_k127_7787952_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000958 139.0
HKD1_k127_7787952_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000015 118.0
HKD1_k127_7787952_12 Protein of unknown function (DUF2662) - - - 0.00000000001039 78.0
HKD1_k127_7787952_13 Adenylate cyclase - - - 0.00000000002394 77.0
HKD1_k127_7787952_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 441.0
HKD1_k127_7787952_3 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 394.0
HKD1_k127_7787952_4 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 351.0
HKD1_k127_7787952_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 372.0
HKD1_k127_7787952_6 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006434 298.0
HKD1_k127_7787952_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006802 299.0
HKD1_k127_7787952_8 PFAM peptidase M24 K01262,K01271,K01274 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000116 245.0
HKD1_k127_7787952_9 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000002746 216.0
HKD1_k127_782837_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.841e-273 856.0
HKD1_k127_782837_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 3.943e-269 833.0
HKD1_k127_782837_10 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 381.0
HKD1_k127_782837_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 392.0
HKD1_k127_782837_12 Transcriptional regulator with HTH domain and aminotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 369.0
HKD1_k127_782837_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 355.0
HKD1_k127_782837_14 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 337.0
HKD1_k127_782837_15 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 340.0
HKD1_k127_782837_16 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 323.0
HKD1_k127_782837_17 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002656 291.0
HKD1_k127_782837_18 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000683 286.0
HKD1_k127_782837_19 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006761 250.0
HKD1_k127_782837_2 Histidine Phosphotransfer domain K11527 - 2.7.13.3 8.834e-267 874.0
HKD1_k127_782837_20 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000000000000000000000000000000000000000000000000000000000008225 255.0
HKD1_k127_782837_21 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000004888 200.0
HKD1_k127_782837_22 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000347 209.0
HKD1_k127_782837_23 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000002911 186.0
HKD1_k127_782837_24 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000002654 191.0
HKD1_k127_782837_25 Methyltransferase, chemotaxis proteins K00575 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564 2.1.1.80 0.00000000000000000000000000000000000001614 159.0
HKD1_k127_782837_26 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.00000000000000000000000000000000000001826 164.0
HKD1_k127_782837_27 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000005499 117.0
HKD1_k127_782837_28 RNA recognition motif - - - 0.000000000000000000000005284 119.0
HKD1_k127_782837_29 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000001914 94.0
HKD1_k127_782837_3 Insulinase (Peptidase family M16) - - - 1.542e-198 628.0
HKD1_k127_782837_30 response regulator - - - 0.000000000000147 82.0
HKD1_k127_782837_31 Protein tyrosine kinase K08884 - 2.7.11.1 0.00000000000292 79.0
HKD1_k127_782837_4 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 560.0
HKD1_k127_782837_5 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 561.0
HKD1_k127_782837_6 response regulator, receiver K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 529.0
HKD1_k127_782837_7 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 466.0
HKD1_k127_782837_8 Peptidase, M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 445.0
HKD1_k127_782837_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 424.0
HKD1_k127_7944332_0 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 2.577e-247 791.0
HKD1_k127_7944332_1 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 511.0
HKD1_k127_7944332_10 YCII-related domain - - - 0.0000000000000000000000000000000000000012 150.0
HKD1_k127_7944332_11 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000002059 165.0
HKD1_k127_7944332_12 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000002518 143.0
HKD1_k127_7944332_13 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.0000000000000000000000000000001154 136.0
HKD1_k127_7944332_14 - - - - 0.0000000005487 71.0
HKD1_k127_7944332_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000009941 63.0
HKD1_k127_7944332_16 Guanylyl transferase CofC like K09931 - - 0.00001208 48.0
HKD1_k127_7944332_2 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 447.0
HKD1_k127_7944332_3 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 413.0
HKD1_k127_7944332_4 radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 396.0
HKD1_k127_7944332_5 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 383.0
HKD1_k127_7944332_6 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000225 259.0
HKD1_k127_7944332_7 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005778 258.0
HKD1_k127_7944332_8 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001121 256.0
HKD1_k127_7944332_9 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000472 202.0
HKD1_k127_91011_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 5.684e-320 996.0
HKD1_k127_91011_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.592e-220 698.0
HKD1_k127_91011_10 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 303.0
HKD1_k127_91011_11 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 293.0
HKD1_k127_91011_12 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001889 278.0
HKD1_k127_91011_13 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 274.0
HKD1_k127_91011_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004387 270.0
HKD1_k127_91011_15 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006424 264.0
HKD1_k127_91011_16 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000009064 242.0
HKD1_k127_91011_17 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000001562 268.0
HKD1_k127_91011_18 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000007027 250.0
HKD1_k127_91011_19 Bacterial Ig-like domain (group 3) - - - 0.00000000000000000000000000000000000000000000000000000000001832 238.0
HKD1_k127_91011_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 527.0
HKD1_k127_91011_20 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000008936 188.0
HKD1_k127_91011_21 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000007864 165.0
HKD1_k127_91011_22 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000007294 168.0
HKD1_k127_91011_23 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000001774 171.0
HKD1_k127_91011_24 Molybdenum cofactor biosynthesis protein B - - - 0.0000000000000000000000000000000000004387 148.0
HKD1_k127_91011_25 membrane - - - 0.0000000000000000000000000000000000004845 151.0
HKD1_k127_91011_26 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000752 143.0
HKD1_k127_91011_27 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000005604 124.0
HKD1_k127_91011_28 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000001215 103.0
HKD1_k127_91011_29 Polyketide cyclase / dehydrase and lipid transport K09386 - - 0.000000000000000001001 94.0
HKD1_k127_91011_3 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 474.0
HKD1_k127_91011_30 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000009272 100.0
HKD1_k127_91011_31 Glycosyltransferase like family 2 - - - 0.00000000005362 76.0
HKD1_k127_91011_32 BON domain - - - 0.0004613 51.0
HKD1_k127_91011_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 415.0
HKD1_k127_91011_6 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 413.0
HKD1_k127_91011_7 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 380.0
HKD1_k127_91011_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 369.0
HKD1_k127_91011_9 Secretory lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 367.0
HKD1_k127_97218_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.087e-269 841.0
HKD1_k127_97218_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 485.0
HKD1_k127_97218_10 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001556 271.0
HKD1_k127_97218_11 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001577 241.0
HKD1_k127_97218_13 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000001063 211.0
HKD1_k127_97218_14 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000522 194.0
HKD1_k127_97218_15 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000001272 198.0
HKD1_k127_97218_16 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000508 181.0
HKD1_k127_97218_17 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000005931 197.0
HKD1_k127_97218_18 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000003099 184.0
HKD1_k127_97218_19 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000397 173.0
HKD1_k127_97218_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 446.0
HKD1_k127_97218_20 PFAM Helix-turn-helix, type 11 domain protein - - - 0.000000000000000000000000000000000008179 150.0
HKD1_k127_97218_21 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000008921 141.0
HKD1_k127_97218_22 - - - - 0.000000000000000000000000000002634 129.0
HKD1_k127_97218_23 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000004065 133.0
HKD1_k127_97218_24 Uncharacterized protein family UPF0029 - - - 0.000000000000000000000001726 119.0
HKD1_k127_97218_25 cell redox homeostasis - - - 0.00000000000000000000001942 107.0
HKD1_k127_97218_26 peptidyl-tyrosine sulfation - - - 0.0000000000000000000003569 108.0
HKD1_k127_97218_27 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000067 85.0
HKD1_k127_97218_28 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000004661 80.0
HKD1_k127_97218_29 DoxX K16937 - 1.8.5.2 0.0000000001508 68.0
HKD1_k127_97218_3 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 419.0
HKD1_k127_97218_30 MerR HTH family regulatory protein K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000001565 58.0
HKD1_k127_97218_31 TM2 domain - - - 0.00006586 51.0
HKD1_k127_97218_4 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 404.0
HKD1_k127_97218_5 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 390.0
HKD1_k127_97218_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 359.0
HKD1_k127_97218_7 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 325.0
HKD1_k127_97218_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000002948 291.0
HKD1_k127_97218_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 272.0