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Overview

ID MAG01767
Name HKD1_bin.87
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class BSN033
Order BSN033
Family UBA1163
Genus UBA1163
Species
Assembly information
Completeness (%) 85.24
Contamination (%) 5.8
GC content (%) 45.0
N50 (bp) 17,625
Genome size (bp) 3,577,592

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3333

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1008200_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.504e-201 643.0
HKD1_k127_1008200_1 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 405.0
HKD1_k127_1008200_2 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 294.0
HKD1_k127_1008200_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 269.0
HKD1_k127_1008200_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008558 254.0
HKD1_k127_1008200_5 - - - - 0.0000000000000000000000000002591 120.0
HKD1_k127_1008200_6 sterol carrier protein - - - 0.00000000000000000000000002271 111.0
HKD1_k127_1009535_0 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 2.545e-198 623.0
HKD1_k127_1009535_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 482.0
HKD1_k127_1009535_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 296.0
HKD1_k127_1009535_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000000000000463 139.0
HKD1_k127_1009535_4 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000004376 138.0
HKD1_k127_1009535_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000002961 74.0
HKD1_k127_1020100_0 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 349.0
HKD1_k127_1020100_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 353.0
HKD1_k127_1020100_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 338.0
HKD1_k127_1020100_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 329.0
HKD1_k127_1020100_4 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 317.0
HKD1_k127_1020100_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001039 200.0
HKD1_k127_1020100_6 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000009749 123.0
HKD1_k127_1020100_7 - - - - 0.00000000000000000004427 91.0
HKD1_k127_1023958_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 3.471e-208 675.0
HKD1_k127_1023958_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 375.0
HKD1_k127_1023958_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 332.0
HKD1_k127_1023958_3 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000925 269.0
HKD1_k127_1023958_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001578 212.0
HKD1_k127_1023958_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000001578 163.0
HKD1_k127_1023958_6 PilZ domain - - - 0.00001139 54.0
HKD1_k127_1042980_0 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 479.0
HKD1_k127_1042980_1 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 - 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 385.0
HKD1_k127_1042980_10 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000005196 232.0
HKD1_k127_1042980_11 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000003196 158.0
HKD1_k127_1042980_12 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000009829 107.0
HKD1_k127_1042980_13 EamA-like transporter family - - - 0.00000000000000009543 85.0
HKD1_k127_1042980_14 COG0500 SAM-dependent methyltransferases - - - 0.0000000000004556 78.0
HKD1_k127_1042980_15 inositol 2-dehydrogenase activity - - - 0.000000000805 70.0
HKD1_k127_1042980_16 Tyrosine phosphatase family - - - 0.000000003029 62.0
HKD1_k127_1042980_17 PAP2 superfamily K19302 - 3.6.1.27 0.000002842 59.0
HKD1_k127_1042980_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 363.0
HKD1_k127_1042980_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 316.0
HKD1_k127_1042980_4 glycosyl transferase family 39 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 312.0
HKD1_k127_1042980_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K10011 - 1.1.1.305,2.1.2.13,2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 298.0
HKD1_k127_1042980_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 304.0
HKD1_k127_1042980_7 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 298.0
HKD1_k127_1042980_8 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004841 284.0
HKD1_k127_1042980_9 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000008277 258.0
HKD1_k127_106781_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.36e-282 884.0
HKD1_k127_106781_1 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 554.0
HKD1_k127_106781_10 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005657 246.0
HKD1_k127_106781_11 - - - - 0.00000000000000000000000000000000000000006005 158.0
HKD1_k127_106781_12 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000004276 149.0
HKD1_k127_106781_13 Lysin motif - - - 0.000000000000000000000000000000008835 138.0
HKD1_k127_106781_14 transcriptional regulator - - - 0.00000000000000000000000000001051 126.0
HKD1_k127_106781_15 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.00000000000000000000000007008 110.0
HKD1_k127_106781_16 phosphorelay signal transduction system K07658 - - 0.0000000000000000000003779 100.0
HKD1_k127_106781_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000001798 100.0
HKD1_k127_106781_18 Tetratricopeptide repeat - - - 0.000000000000000000002069 106.0
HKD1_k127_106781_19 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000001488 87.0
HKD1_k127_106781_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 526.0
HKD1_k127_106781_20 sodium-dependent phosphate transmembrane transporter activity - - - 0.000000000000000009958 91.0
HKD1_k127_106781_3 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 476.0
HKD1_k127_106781_4 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 469.0
HKD1_k127_106781_5 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 443.0
HKD1_k127_106781_6 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 347.0
HKD1_k127_106781_7 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 323.0
HKD1_k127_106781_8 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 312.0
HKD1_k127_106781_9 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001108 287.0
HKD1_k127_1073745_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 7.343e-225 703.0
HKD1_k127_1073745_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.492e-218 684.0
HKD1_k127_1073745_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000368 237.0
HKD1_k127_1073745_11 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000007408 187.0
HKD1_k127_1073745_12 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000001664 168.0
HKD1_k127_1073745_13 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.00000000000000000000000000000000000008333 144.0
HKD1_k127_1073745_14 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000002568 144.0
HKD1_k127_1073745_15 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000001374 135.0
HKD1_k127_1073745_16 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.000000000000001822 79.0
HKD1_k127_1073745_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 578.0
HKD1_k127_1073745_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 509.0
HKD1_k127_1073745_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 480.0
HKD1_k127_1073745_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 450.0
HKD1_k127_1073745_6 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 422.0
HKD1_k127_1073745_7 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 330.0
HKD1_k127_1073745_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 312.0
HKD1_k127_1073745_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001246 230.0
HKD1_k127_1088227_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 460.0
HKD1_k127_1088227_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 402.0
HKD1_k127_1088227_10 sAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000003681 194.0
HKD1_k127_1088227_11 DsbA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001162 183.0
HKD1_k127_1088227_12 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000002287 188.0
HKD1_k127_1088227_13 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000001544 180.0
HKD1_k127_1088227_14 Histidine kinase - - - 0.000000000000000000000000000000000000002717 168.0
HKD1_k127_1088227_15 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000005235 143.0
HKD1_k127_1088227_16 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000001569 135.0
HKD1_k127_1088227_17 Peptidase family M28 - - - 0.0000000000000000000001867 100.0
HKD1_k127_1088227_18 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000002454 100.0
HKD1_k127_1088227_19 - - - - 0.000000000000000000003625 96.0
HKD1_k127_1088227_2 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 364.0
HKD1_k127_1088227_20 Polymer-forming cytoskeletal - - - 0.000000000000000003832 90.0
HKD1_k127_1088227_21 - - - - 0.0000000000000006905 92.0
HKD1_k127_1088227_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 351.0
HKD1_k127_1088227_4 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004364 272.0
HKD1_k127_1088227_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002403 263.0
HKD1_k127_1088227_6 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001225 244.0
HKD1_k127_1088227_7 3-hydroxyacyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000015 238.0
HKD1_k127_1088227_8 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000006294 205.0
HKD1_k127_1088227_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000001085 196.0
HKD1_k127_1091982_0 extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002272 282.0
HKD1_k127_1091982_1 PFAM AIR synthase related protein K07123 - - 0.000000000000135 72.0
HKD1_k127_1113695_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 2.694e-195 616.0
HKD1_k127_1113695_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 509.0
HKD1_k127_1113695_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000002922 246.0
HKD1_k127_1113695_11 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000001972 244.0
HKD1_k127_1113695_12 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000005743 233.0
HKD1_k127_1113695_13 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000002594 231.0
HKD1_k127_1113695_14 Lipocalin-like domain - - - 0.0000000000000000000000000000000000005461 145.0
HKD1_k127_1113695_15 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000005966 116.0
HKD1_k127_1113695_16 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000006286 111.0
HKD1_k127_1113695_17 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000001253 109.0
HKD1_k127_1113695_18 PFAM thioesterase superfamily K02614 - - 0.0000000000000000005943 91.0
HKD1_k127_1113695_19 - - - - 0.0000000000000002135 85.0
HKD1_k127_1113695_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 455.0
HKD1_k127_1113695_20 Regulatory protein, FmdB family - - - 0.0000000000000006209 81.0
HKD1_k127_1113695_21 Plasmid stability protein K21495 - - 0.00000000002171 68.0
HKD1_k127_1113695_22 Transglycosylase SLT domain - - - 0.00000006203 62.0
HKD1_k127_1113695_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 396.0
HKD1_k127_1113695_4 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 372.0
HKD1_k127_1113695_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 330.0
HKD1_k127_1113695_6 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 300.0
HKD1_k127_1113695_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 288.0
HKD1_k127_1113695_8 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
HKD1_k127_1113695_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001166 248.0
HKD1_k127_11179_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 566.0
HKD1_k127_11179_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 511.0
HKD1_k127_11179_10 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K04488 - - 0.000000000000000000000000000000000000000000000008498 174.0
HKD1_k127_11179_11 domain protein - - - 0.00000000000000000000000000000000000000000000005665 174.0
HKD1_k127_11179_12 PFAM GAF domain - - - 0.0000000000000000000000000000000000000000000005692 171.0
HKD1_k127_11179_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000002977 168.0
HKD1_k127_11179_14 AhpC/TSA family - - - 0.000000000000000000000000000000000000003143 154.0
HKD1_k127_11179_15 Transcriptional regulatory protein, C terminal K07668,K07775 - - 0.000000000000000001358 90.0
HKD1_k127_11179_16 Class III cytochrome C family - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000001691 70.0
HKD1_k127_11179_17 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.0006191 46.0
HKD1_k127_11179_2 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 469.0
HKD1_k127_11179_3 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 368.0
HKD1_k127_11179_4 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 321.0
HKD1_k127_11179_5 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000221 284.0
HKD1_k127_11179_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007897 285.0
HKD1_k127_11179_7 Fe-S-cluster-containing hydrogenase K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004078 263.0
HKD1_k127_11179_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 248.0
HKD1_k127_11179_9 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000007367 211.0
HKD1_k127_11195_0 epimerase dehydratase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 341.0
HKD1_k127_11195_1 glycosyl transferase family 2 K10211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 314.0
HKD1_k127_11195_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003016 284.0
HKD1_k127_11195_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003472 253.0
HKD1_k127_11195_4 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000105 200.0
HKD1_k127_11195_5 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000001124 164.0
HKD1_k127_11195_6 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000008016 148.0
HKD1_k127_11195_7 carotenoid biosynthetic process K10212 - - 0.0000000000000000000000000000000000244 141.0
HKD1_k127_1127182_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 6.019e-213 675.0
HKD1_k127_1127182_1 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 465.0
HKD1_k127_1135491_0 AMP-binding enzyme K01897 - 6.2.1.3 3.712e-215 685.0
HKD1_k127_1135491_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 507.0
HKD1_k127_1135491_10 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000000000000000001421 121.0
HKD1_k127_1135491_12 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000854 124.0
HKD1_k127_1135491_13 lipoprotein involved in nitrous oxide reduction K21601 - - 0.00000000000000000000149 100.0
HKD1_k127_1135491_14 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000002168 81.0
HKD1_k127_1135491_15 - - - - 0.00000000000001073 87.0
HKD1_k127_1135491_17 ABC transporter substrate-binding protein K15551 - - 0.00000003395 66.0
HKD1_k127_1135491_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 471.0
HKD1_k127_1135491_3 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 356.0
HKD1_k127_1135491_4 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 340.0
HKD1_k127_1135491_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 323.0
HKD1_k127_1135491_6 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 259.0
HKD1_k127_1135491_7 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000155 245.0
HKD1_k127_1135491_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.000000000000000000000000000000000000000000000000000000000000007789 224.0
HKD1_k127_1135491_9 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000008314 143.0
HKD1_k127_1147983_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.549e-273 861.0
HKD1_k127_1147983_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 568.0
HKD1_k127_1147983_10 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000002103 203.0
HKD1_k127_1147983_11 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000000000000005434 153.0
HKD1_k127_1147983_12 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000000001085 144.0
HKD1_k127_1147983_13 - - - - 0.000000000000000000000000000000001901 135.0
HKD1_k127_1147983_14 Thioredoxin-like - - - 0.00000000000000000000000002164 115.0
HKD1_k127_1147983_15 PFAM glycine cleavage H-protein - - - 0.00000000000000000000001809 109.0
HKD1_k127_1147983_16 PFAM Excinuclease ABC, C subunit, N-terminal K07461 - - 0.000000000000000004397 86.0
HKD1_k127_1147983_17 Domain of unknown function (DUF4115) - - - 0.00000000000001182 85.0
HKD1_k127_1147983_18 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000001108 57.0
HKD1_k127_1147983_19 rod shape-determining protein MreD K03571 - - 0.00000002482 62.0
HKD1_k127_1147983_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 513.0
HKD1_k127_1147983_3 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 490.0
HKD1_k127_1147983_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 397.0
HKD1_k127_1147983_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 365.0
HKD1_k127_1147983_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 335.0
HKD1_k127_1147983_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
HKD1_k127_1147983_8 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 330.0
HKD1_k127_1147983_9 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 328.0
HKD1_k127_1169734_0 BadF BadG BcrA BcrD - - - 0.0 1537.0
HKD1_k127_1169734_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 508.0
HKD1_k127_1169734_2 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000000003039 121.0
HKD1_k127_1169734_3 Protein of unknown function (DUF3047) - - - 0.000000000000000000004727 96.0
HKD1_k127_1169734_4 amine dehydrogenase activity - - - 0.000006772 52.0
HKD1_k127_1184897_0 Belongs to the glycosyl hydrolase 57 family - - - 1.398e-211 685.0
HKD1_k127_1184897_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 560.0
HKD1_k127_1184897_10 DoxX K15977 - - 0.000000000000000000000000008504 114.0
HKD1_k127_1184897_11 response to heat - - - 0.00000000000000002416 85.0
HKD1_k127_1184897_12 4Fe-4S single cluster domain - - - 0.000000000004931 67.0
HKD1_k127_1184897_13 Transcriptional regulator - - - 0.00001774 47.0
HKD1_k127_1184897_14 CBS domain K07182 - - 0.00003278 52.0
HKD1_k127_1184897_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 501.0
HKD1_k127_1184897_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 416.0
HKD1_k127_1184897_4 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 343.0
HKD1_k127_1184897_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 317.0
HKD1_k127_1184897_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 303.0
HKD1_k127_1184897_7 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000008031 267.0
HKD1_k127_1184897_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000005447 211.0
HKD1_k127_1184897_9 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000001369 192.0
HKD1_k127_1190538_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1017.0
HKD1_k127_1190538_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000004927 212.0
HKD1_k127_1190538_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000003351 201.0
HKD1_k127_1190538_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000009306 199.0
HKD1_k127_1198177_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 379.0
HKD1_k127_1198177_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 307.0
HKD1_k127_1198177_2 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000001745 148.0
HKD1_k127_1198177_3 chromosome segregation K03497 - - 0.000000000000000000000000001433 124.0
HKD1_k127_1198177_4 - - - - 0.000000000000000001922 89.0
HKD1_k127_122854_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.06e-244 773.0
HKD1_k127_122854_1 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 2.366e-198 627.0
HKD1_k127_122854_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 376.0
HKD1_k127_122854_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 355.0
HKD1_k127_122854_12 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 341.0
HKD1_k127_122854_13 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 275.0
HKD1_k127_122854_14 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000001018 253.0
HKD1_k127_122854_15 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000004277 164.0
HKD1_k127_122854_16 Essential cell division protein K03589 - - 0.0000000000000000000000000000000000007324 149.0
HKD1_k127_122854_17 Prolyl oligopeptidase family K06889,K07397 - - 0.0000000001335 64.0
HKD1_k127_122854_18 Cell division protein FtsL - - - 0.0000000002202 66.0
HKD1_k127_122854_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 610.0
HKD1_k127_122854_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 614.0
HKD1_k127_122854_4 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 554.0
HKD1_k127_122854_5 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 481.0
HKD1_k127_122854_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 480.0
HKD1_k127_122854_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 477.0
HKD1_k127_122854_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 435.0
HKD1_k127_122854_9 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 378.0
HKD1_k127_126737_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.946e-271 842.0
HKD1_k127_126737_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.239e-197 632.0
HKD1_k127_126737_10 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009783 309.0
HKD1_k127_126737_11 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 308.0
HKD1_k127_126737_12 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 306.0
HKD1_k127_126737_13 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 301.0
HKD1_k127_126737_14 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003728 276.0
HKD1_k127_126737_15 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000003813 207.0
HKD1_k127_126737_16 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000001915 211.0
HKD1_k127_126737_17 CHAT domain - - - 0.0000000000000000000000000000007767 141.0
HKD1_k127_126737_18 KR domain K00059 - 1.1.1.100 0.00000000000000000001489 101.0
HKD1_k127_126737_19 Psort location Cytoplasmic, score 9.98 K04069,K20037 - 1.97.1.4 0.00000000006654 66.0
HKD1_k127_126737_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 602.0
HKD1_k127_126737_20 Receptor family ligand binding region K01999 - - 0.0000000005582 72.0
HKD1_k127_126737_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 372.0
HKD1_k127_126737_4 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 366.0
HKD1_k127_126737_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
HKD1_k127_126737_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 346.0
HKD1_k127_126737_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 346.0
HKD1_k127_126737_8 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 336.0
HKD1_k127_126737_9 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 329.0
HKD1_k127_1273392_0 Neisseria PilC beta-propeller domain K02674 - - 0.00000000000000000000000000000000000000000000000000000002858 226.0
HKD1_k127_1273392_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000001382 220.0
HKD1_k127_1273392_2 Tetratricopeptide repeats - - - 0.0000000000000000000002099 108.0
HKD1_k127_1273392_3 pilus assembly protein PilW - - - 0.000000000000000000000902 106.0
HKD1_k127_1273392_4 peptidyl-tyrosine sulfation - - - 0.000000000000001604 87.0
HKD1_k127_1273392_5 PilX N-terminal - - - 0.0000000001135 68.0
HKD1_k127_1273392_6 Prokaryotic N-terminal methylation motif K08084 - - 0.0000001105 59.0
HKD1_k127_1273392_7 PilX N-terminal - - - 0.000003923 56.0
HKD1_k127_1273392_8 Prokaryotic N-terminal methylation motif K02671 - - 0.000007195 53.0
HKD1_k127_1274495_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 2.785e-291 914.0
HKD1_k127_1274495_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 514.0
HKD1_k127_1274495_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 410.0
HKD1_k127_1274495_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
HKD1_k127_1274495_4 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000003142 185.0
HKD1_k127_1274495_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000001321 125.0
HKD1_k127_1295502_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1141.0
HKD1_k127_1295502_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 575.0
HKD1_k127_1295502_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000003534 220.0
HKD1_k127_1295502_11 SAM-dependent RNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000455 205.0
HKD1_k127_1295502_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000583 168.0
HKD1_k127_1295502_13 S23 ribosomal protein - - - 0.000000000000000000000000000000000000005102 148.0
HKD1_k127_1295502_14 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000002894 130.0
HKD1_k127_1295502_15 KH domain K06960 - - 0.00000000000000000000000000001788 119.0
HKD1_k127_1295502_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000001872 123.0
HKD1_k127_1295502_17 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000009194 106.0
HKD1_k127_1295502_18 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000007312 51.0
HKD1_k127_1295502_19 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00003126 50.0
HKD1_k127_1295502_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 557.0
HKD1_k127_1295502_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 518.0
HKD1_k127_1295502_4 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 494.0
HKD1_k127_1295502_5 Thiamine-phosphate synthase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 458.0
HKD1_k127_1295502_6 Thi4 family K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 361.0
HKD1_k127_1295502_7 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 314.0
HKD1_k127_1295502_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
HKD1_k127_1295502_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000005035 244.0
HKD1_k127_1315370_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 1.249e-197 642.0
HKD1_k127_1315370_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 466.0
HKD1_k127_1315370_10 membrane-associated protein K03975 - - 0.0000000000000000000000002341 113.0
HKD1_k127_1315370_11 branched-chain amino acid - - - 0.00000000000000000002646 93.0
HKD1_k127_1315370_12 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000002777 80.0
HKD1_k127_1315370_13 AzlC protein - - - 0.00000000000005779 75.0
HKD1_k127_1315370_14 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.000000000001072 77.0
HKD1_k127_1315370_2 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 313.0
HKD1_k127_1315370_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008578 276.0
HKD1_k127_1315370_4 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001919 243.0
HKD1_k127_1315370_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000221 205.0
HKD1_k127_1315370_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000002182 205.0
HKD1_k127_1315370_7 membrane K08978 - - 0.0000000000000000000000000000000000002654 145.0
HKD1_k127_1315370_8 PFAM AzlC family protein - - - 0.00000000000000000000000000000000001383 141.0
HKD1_k127_1315370_9 - - - - 0.0000000000000000000000001516 108.0
HKD1_k127_1322443_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.914e-298 950.0
HKD1_k127_1322443_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.899e-216 682.0
HKD1_k127_1322443_10 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 471.0
HKD1_k127_1322443_11 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 465.0
HKD1_k127_1322443_12 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 457.0
HKD1_k127_1322443_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 464.0
HKD1_k127_1322443_14 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 430.0
HKD1_k127_1322443_15 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 396.0
HKD1_k127_1322443_16 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 392.0
HKD1_k127_1322443_17 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 379.0
HKD1_k127_1322443_18 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 378.0
HKD1_k127_1322443_19 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 366.0
HKD1_k127_1322443_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 8.188e-216 687.0
HKD1_k127_1322443_20 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 347.0
HKD1_k127_1322443_21 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 332.0
HKD1_k127_1322443_22 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 323.0
HKD1_k127_1322443_23 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 312.0
HKD1_k127_1322443_24 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 314.0
HKD1_k127_1322443_25 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 302.0
HKD1_k127_1322443_26 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 302.0
HKD1_k127_1322443_27 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 296.0
HKD1_k127_1322443_28 Radical_SAM C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 299.0
HKD1_k127_1322443_29 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 293.0
HKD1_k127_1322443_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 3.464e-215 710.0
HKD1_k127_1322443_30 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 293.0
HKD1_k127_1322443_31 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000897 299.0
HKD1_k127_1322443_32 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002215 279.0
HKD1_k127_1322443_33 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000211 280.0
HKD1_k127_1322443_34 PFAM 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001805 272.0
HKD1_k127_1322443_35 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004922 261.0
HKD1_k127_1322443_36 ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005272 253.0
HKD1_k127_1322443_37 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004142 254.0
HKD1_k127_1322443_38 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000317 253.0
HKD1_k127_1322443_39 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000001079 245.0
HKD1_k127_1322443_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.278e-198 627.0
HKD1_k127_1322443_40 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000001877 248.0
HKD1_k127_1322443_41 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000007063 237.0
HKD1_k127_1322443_42 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000001014 241.0
HKD1_k127_1322443_43 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000001487 219.0
HKD1_k127_1322443_44 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000001232 224.0
HKD1_k127_1322443_45 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.000000000000000000000000000000000000000000000000000006708 205.0
HKD1_k127_1322443_46 - - - - 0.00000000000000000000000000000000000000000000000000003853 190.0
HKD1_k127_1322443_47 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000003981 195.0
HKD1_k127_1322443_48 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000006646 199.0
HKD1_k127_1322443_49 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001898 197.0
HKD1_k127_1322443_5 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.035e-195 621.0
HKD1_k127_1322443_50 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000046 187.0
HKD1_k127_1322443_51 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000001982 193.0
HKD1_k127_1322443_52 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000003729 188.0
HKD1_k127_1322443_53 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000001178 186.0
HKD1_k127_1322443_54 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000001366 193.0
HKD1_k127_1322443_55 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000008253 172.0
HKD1_k127_1322443_56 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000263 152.0
HKD1_k127_1322443_57 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000002733 149.0
HKD1_k127_1322443_58 Cysteine-rich domain - - - 0.00000000000000000000000000005878 135.0
HKD1_k127_1322443_59 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000007246 128.0
HKD1_k127_1322443_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 602.0
HKD1_k127_1322443_60 - - - - 0.0000000000000000000000002129 117.0
HKD1_k127_1322443_61 Rhodanese Homology Domain - - - 0.000000000000000000000005438 102.0
HKD1_k127_1322443_62 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000001112 99.0
HKD1_k127_1322443_63 electron transfer activity K00428 - 1.11.1.5 0.00000000000000000000005749 102.0
HKD1_k127_1322443_64 - - - - 0.00000000000000000000007225 104.0
HKD1_k127_1322443_65 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000008535 97.0
HKD1_k127_1322443_66 Universal stress protein family - - - 0.0000000000000000000009198 102.0
HKD1_k127_1322443_67 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000001559 94.0
HKD1_k127_1322443_68 protein conserved in archaea - - - 0.0000000000000000005449 93.0
HKD1_k127_1322443_69 Putative ATP-dependant zinc protease - - - 0.000000000000000007164 89.0
HKD1_k127_1322443_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 564.0
HKD1_k127_1322443_70 Protein of unknown function (DUF3426) - - - 0.0000000000000001247 91.0
HKD1_k127_1322443_73 prohibitin homologues - - - 0.000000001309 62.0
HKD1_k127_1322443_74 Outer membrane protein (OmpH-like) K06142 - - 0.00000004959 61.0
HKD1_k127_1322443_75 PFAM GGDEF domain containing protein - - - 0.000001949 58.0
HKD1_k127_1322443_8 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 535.0
HKD1_k127_1322443_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 514.0
HKD1_k127_1330533_0 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 464.0
HKD1_k127_1330533_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001394 241.0
HKD1_k127_1330533_2 Ser Thr phosphatase family protein K07098 - - 0.000000003717 58.0
HKD1_k127_1396161_0 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 560.0
HKD1_k127_1396161_1 PFAM inner-membrane translocator K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 521.0
HKD1_k127_1396161_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 476.0
HKD1_k127_1396161_3 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 423.0
HKD1_k127_1396161_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000563 207.0
HKD1_k127_1396161_5 Archaebacterial flagellin - - - 0.00000000000000000000000000000000000000001205 160.0
HKD1_k127_1396161_6 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000003977 143.0
HKD1_k127_1403098_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 7.455e-234 736.0
HKD1_k127_1403098_1 PFAM Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 400.0
HKD1_k127_1403098_2 rubredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 - 0.0000000000000000001121 94.0
HKD1_k127_1403098_3 PFAM Nitroreductase - - - 0.00000000000000004404 83.0
HKD1_k127_1403098_4 PFAM ThiamineS - - - 0.000000005297 62.0
HKD1_k127_1403098_5 PFAM Nitroreductase - - - 0.00000189 50.0
HKD1_k127_1414704_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 330.0
HKD1_k127_1414704_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000001578 133.0
HKD1_k127_15163_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 4.419e-203 649.0
HKD1_k127_15163_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 486.0
HKD1_k127_15163_10 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000003349 96.0
HKD1_k127_15163_11 LppC putative lipoprotein - - - 0.00002136 52.0
HKD1_k127_15163_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 431.0
HKD1_k127_15163_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 402.0
HKD1_k127_15163_4 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 333.0
HKD1_k127_15163_5 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000009126 165.0
HKD1_k127_15163_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000001634 151.0
HKD1_k127_15163_7 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000004254 151.0
HKD1_k127_15163_8 Ribonuclease H K03469 - 3.1.26.4 0.000000000000000000000000000000006137 132.0
HKD1_k127_15163_9 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000004436 129.0
HKD1_k127_151902_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1171.0
HKD1_k127_151902_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 568.0
HKD1_k127_151902_10 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 349.0
HKD1_k127_151902_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 334.0
HKD1_k127_151902_12 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
HKD1_k127_151902_13 ThiS-like ubiquitin K03148 - 2.7.7.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 319.0
HKD1_k127_151902_14 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 302.0
HKD1_k127_151902_15 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 312.0
HKD1_k127_151902_16 Nucleotidyl transferase K00966,K21210 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001742 263.0
HKD1_k127_151902_17 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002685 275.0
HKD1_k127_151902_18 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000147 264.0
HKD1_k127_151902_19 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000003661 237.0
HKD1_k127_151902_2 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 549.0
HKD1_k127_151902_20 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000004178 230.0
HKD1_k127_151902_21 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000006553 224.0
HKD1_k127_151902_22 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000615 216.0
HKD1_k127_151902_23 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000003767 208.0
HKD1_k127_151902_24 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000004669 202.0
HKD1_k127_151902_25 lysyltransferase activity K07027,K20468 - - 0.000000000000000000000000000000001673 142.0
HKD1_k127_151902_26 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000001419 113.0
HKD1_k127_151902_27 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000001239 115.0
HKD1_k127_151902_28 23S rRNA-intervening sequence protein - - - 0.000000000000000000000002702 106.0
HKD1_k127_151902_29 Glycine cleavage H-protein - - - 0.000000000000000000000009618 102.0
HKD1_k127_151902_3 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 441.0
HKD1_k127_151902_30 Tetratricopeptide repeat - - - 0.0000000000000000000002476 106.0
HKD1_k127_151902_31 Protein involved in cellulose biosynthesis - - - 0.000000000003105 78.0
HKD1_k127_151902_32 ubiE/COQ5 methyltransferase family - - - 0.000000000005515 75.0
HKD1_k127_151902_33 - - - - 0.00008611 53.0
HKD1_k127_151902_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 426.0
HKD1_k127_151902_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 415.0
HKD1_k127_151902_6 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 417.0
HKD1_k127_151902_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 411.0
HKD1_k127_151902_8 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 396.0
HKD1_k127_151902_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 364.0
HKD1_k127_1522395_0 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 338.0
HKD1_k127_1522395_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 329.0
HKD1_k127_1522395_2 Yip1 domain - - - 0.00000000000000000000000008443 120.0
HKD1_k127_1522395_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000004317 61.0
HKD1_k127_1522622_0 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 402.0
HKD1_k127_1522622_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007079 251.0
HKD1_k127_1522622_2 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000006041 124.0
HKD1_k127_1522622_3 PFAM ResB family protein K07399 - - 0.0000000000000005932 79.0
HKD1_k127_1522824_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.815e-254 799.0
HKD1_k127_1522824_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 614.0
HKD1_k127_1522824_10 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000001113 129.0
HKD1_k127_1522824_2 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 479.0
HKD1_k127_1522824_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 419.0
HKD1_k127_1522824_4 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 362.0
HKD1_k127_1522824_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 353.0
HKD1_k127_1522824_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 336.0
HKD1_k127_1522824_7 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002554 284.0
HKD1_k127_1522824_8 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005441 276.0
HKD1_k127_1522824_9 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000004968 220.0
HKD1_k127_1550874_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1060.0
HKD1_k127_1550874_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.92e-313 973.0
HKD1_k127_1550874_10 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.398e-194 614.0
HKD1_k127_1550874_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 538.0
HKD1_k127_1550874_12 PFAM AMP-dependent synthetase and ligase K00666,K01897,K12508 - 6.2.1.3,6.2.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 451.0
HKD1_k127_1550874_13 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 432.0
HKD1_k127_1550874_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 412.0
HKD1_k127_1550874_15 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 378.0
HKD1_k127_1550874_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 319.0
HKD1_k127_1550874_17 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 311.0
HKD1_k127_1550874_18 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 297.0
HKD1_k127_1550874_19 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 291.0
HKD1_k127_1550874_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.679e-288 913.0
HKD1_k127_1550874_20 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001474 276.0
HKD1_k127_1550874_21 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001902 277.0
HKD1_k127_1550874_22 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000007564 225.0
HKD1_k127_1550874_23 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
HKD1_k127_1550874_24 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000001137 215.0
HKD1_k127_1550874_25 GntR family - - - 0.000000000000000000000000000000000000000000000000000000000002667 216.0
HKD1_k127_1550874_26 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000003634 181.0
HKD1_k127_1550874_27 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000002834 191.0
HKD1_k127_1550874_28 Protease prsW family - - - 0.00000000000000000000000000000000000000000000004275 180.0
HKD1_k127_1550874_29 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000000000000000000000001369 176.0
HKD1_k127_1550874_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.569e-259 807.0
HKD1_k127_1550874_30 Involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000001444 176.0
HKD1_k127_1550874_31 overlaps another CDS with the same product name K07112 - - 0.000000000000000000000000000000000000000000005651 166.0
HKD1_k127_1550874_32 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000001046 153.0
HKD1_k127_1550874_33 Methyltransferase domain - - - 0.0000000000000000000000000000000000000558 160.0
HKD1_k127_1550874_34 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000003902 145.0
HKD1_k127_1550874_35 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000001834 149.0
HKD1_k127_1550874_36 NMT1-like family K02051 - - 0.00000000000000000000000000000000001135 148.0
HKD1_k127_1550874_37 - - - - 0.0000000000000000000000000000000009994 132.0
HKD1_k127_1550874_38 - - - - 0.0000000000000000000000000000309 125.0
HKD1_k127_1550874_39 - - - - 0.00000000000000000000000001732 111.0
HKD1_k127_1550874_4 Cytochrome c - - - 1.308e-258 806.0
HKD1_k127_1550874_40 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000008666 112.0
HKD1_k127_1550874_41 Sulphur transport K07112 - - 0.0000000000001066 70.0
HKD1_k127_1550874_42 glutaredoxin-like protein, YruB-family - - - 0.0000000000007462 70.0
HKD1_k127_1550874_43 DNA excision K02806 - - 0.00000000001582 67.0
HKD1_k127_1550874_44 - - - - 0.000000124 59.0
HKD1_k127_1550874_45 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0005693 43.0
HKD1_k127_1550874_46 - - - - 0.0006343 43.0
HKD1_k127_1550874_5 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 3.557e-251 786.0
HKD1_k127_1550874_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.506e-220 705.0
HKD1_k127_1550874_7 PFAM Enoyl-CoA hydratase isomerase - - - 1.941e-214 685.0
HKD1_k127_1550874_8 von Willebrand factor, type A K07114 - - 2.559e-207 659.0
HKD1_k127_1550874_9 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.537e-204 641.0
HKD1_k127_1561895_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 2.162e-271 854.0
HKD1_k127_1561895_1 fatty acid transporter K02106 - - 1.11e-197 626.0
HKD1_k127_1561895_10 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 344.0
HKD1_k127_1561895_11 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 317.0
HKD1_k127_1561895_12 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 309.0
HKD1_k127_1561895_13 Amino acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 293.0
HKD1_k127_1561895_14 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003194 251.0
HKD1_k127_1561895_15 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001249 249.0
HKD1_k127_1561895_16 Thymidylate synthase K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000003778 240.0
HKD1_k127_1561895_17 Alpha beta hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000009854 232.0
HKD1_k127_1561895_18 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K20445 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000003212 221.0
HKD1_k127_1561895_19 - - - - 0.000000000000000000000000000000000000000000000000000000000001575 220.0
HKD1_k127_1561895_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K20449 - 1.3.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 607.0
HKD1_k127_1561895_20 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000003459 216.0
HKD1_k127_1561895_21 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000000000005813 209.0
HKD1_k127_1561895_22 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K09740 - - 0.00000000000000000000000000000000000000000000000000000003274 207.0
HKD1_k127_1561895_23 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000002552 151.0
HKD1_k127_1561895_24 PFAM methyltransferase K15460 - 2.1.1.223 0.000000000000000000000000000000000000004011 151.0
HKD1_k127_1561895_25 Thioredoxin-like - - - 0.000000000000000000000000000000004028 134.0
HKD1_k127_1561895_26 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000006617 123.0
HKD1_k127_1561895_28 PFAM peptidase - - - 0.0000006707 57.0
HKD1_k127_1561895_29 Zinc dependent phospholipase C - - - 0.00000112 60.0
HKD1_k127_1561895_3 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 516.0
HKD1_k127_1561895_30 - - - - 0.0003415 49.0
HKD1_k127_1561895_4 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 525.0
HKD1_k127_1561895_5 Amidohydrolase family K15358 - 3.5.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 504.0
HKD1_k127_1561895_6 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 433.0
HKD1_k127_1561895_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 425.0
HKD1_k127_1561895_8 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 346.0
HKD1_k127_1561895_9 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 332.0
HKD1_k127_1571412_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 387.0
HKD1_k127_1571412_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 356.0
HKD1_k127_1571412_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000005093 75.0
HKD1_k127_1571412_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 325.0
HKD1_k127_1571412_3 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
HKD1_k127_1571412_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001101 278.0
HKD1_k127_1571412_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
HKD1_k127_1571412_6 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001775 244.0
HKD1_k127_1571412_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000002928 178.0
HKD1_k127_1571412_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000008364 150.0
HKD1_k127_1571412_9 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000001796 84.0
HKD1_k127_1587566_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 335.0
HKD1_k127_1587566_1 alpha/beta hydrolase fold K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 305.0
HKD1_k127_1587566_10 AsmA-like C-terminal region K07289 - - 0.00000000007054 75.0
HKD1_k127_1587566_11 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000211 61.0
HKD1_k127_1587566_2 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004128 282.0
HKD1_k127_1587566_3 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001936 243.0
HKD1_k127_1587566_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000168 228.0
HKD1_k127_1587566_5 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000002119 212.0
HKD1_k127_1587566_6 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000191 189.0
HKD1_k127_1587566_7 Helix-hairpin-helix motif - - - 0.00000000000000000000000000000000000000008925 158.0
HKD1_k127_1587566_8 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000001264 139.0
HKD1_k127_1587566_9 - - - - 0.00000000000000000000004124 101.0
HKD1_k127_1644167_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 283.0
HKD1_k127_1644167_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001447 259.0
HKD1_k127_1644167_2 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000114 191.0
HKD1_k127_1644167_3 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000002433 187.0
HKD1_k127_1644167_4 Cytochrome c mono- and diheme variants - - - 0.00000000000000000000000000000000000000001454 159.0
HKD1_k127_1644167_5 membrane - - - 0.0000000000000000000000000000000004646 134.0
HKD1_k127_1644167_6 YtxH-like protein - - - 0.0000000000000000000000000009593 115.0
HKD1_k127_1644167_7 Smr domain - - - 0.0000000000000000000000001441 108.0
HKD1_k127_1644167_8 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000621 99.0
HKD1_k127_1644167_9 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000005955 82.0
HKD1_k127_1708685_0 BadF BadG BcrA BcrD - - - 0.0 1083.0
HKD1_k127_1708685_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.939e-259 815.0
HKD1_k127_1708685_2 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 521.0
HKD1_k127_1729588_0 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 396.0
HKD1_k127_1729588_1 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 394.0
HKD1_k127_1729588_2 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000003423 209.0
HKD1_k127_1729588_3 COG COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000241 205.0
HKD1_k127_1729588_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000001579 195.0
HKD1_k127_1770199_0 Domain of unknown function (DUF362) - - - 2.154e-196 620.0
HKD1_k127_1770199_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
HKD1_k127_1770199_2 PFAM 2-nitropropane dioxygenase NPD - - - 0.000000000000000000000000234 106.0
HKD1_k127_17731_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.461e-206 648.0
HKD1_k127_17731_1 glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 371.0
HKD1_k127_17731_2 Histidine kinase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000003372 240.0
HKD1_k127_17731_3 PFAM response regulator receiver K02481,K07712 - - 0.0000001021 57.0
HKD1_k127_177724_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.275e-256 796.0
HKD1_k127_177724_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124,K07307 - - 0.000000000000000000000000000000000000000000000000009522 185.0
HKD1_k127_177724_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000003499 117.0
HKD1_k127_177724_3 - - - - 0.0000000000000000000000000777 112.0
HKD1_k127_177724_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000002891 109.0
HKD1_k127_180935_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1082.0
HKD1_k127_180935_1 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 9.969e-204 643.0
HKD1_k127_180935_2 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 452.0
HKD1_k127_180935_3 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003135 247.0
HKD1_k127_180935_4 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000002086 205.0
HKD1_k127_1873300_0 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 367.0
HKD1_k127_1873300_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 346.0
HKD1_k127_1873300_10 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000002341 183.0
HKD1_k127_1873300_11 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000004867 170.0
HKD1_k127_1873300_12 GDP-mannose 4,6 dehydratase K15789 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008743,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.103 0.00000000000000000000000000000000000000000001159 175.0
HKD1_k127_1873300_13 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000006541 92.0
HKD1_k127_1873300_14 Putative regulatory protein - - - 0.00000000000172 68.0
HKD1_k127_1873300_2 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
HKD1_k127_1873300_3 branched-chain amino acid transmembrane transporter activity K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 281.0
HKD1_k127_1873300_4 ABC transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001516 264.0
HKD1_k127_1873300_5 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004522 271.0
HKD1_k127_1873300_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000005459 229.0
HKD1_k127_1873300_7 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000002456 218.0
HKD1_k127_1873300_8 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000001972 203.0
HKD1_k127_1873300_9 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000000009285 184.0
HKD1_k127_188219_0 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 598.0
HKD1_k127_188219_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 460.0
HKD1_k127_188219_2 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 401.0
HKD1_k127_188219_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 311.0
HKD1_k127_189642_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000303 247.0
HKD1_k127_189642_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 0.0000000000000000000000000000000000000000275 159.0
HKD1_k127_189642_2 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000007841 101.0
HKD1_k127_1941984_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004192 278.0
HKD1_k127_1941984_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000004123 156.0
HKD1_k127_1941984_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000001515 95.0
HKD1_k127_2012595_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10,2.2.1.8 0.0 1020.0
HKD1_k127_2012595_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 1.89e-252 807.0
HKD1_k127_2012595_10 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 348.0
HKD1_k127_2012595_11 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 343.0
HKD1_k127_2012595_12 Urea transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 347.0
HKD1_k127_2012595_13 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 329.0
HKD1_k127_2012595_14 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 319.0
HKD1_k127_2012595_15 aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 314.0
HKD1_k127_2012595_16 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009565 276.0
HKD1_k127_2012595_17 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001308 269.0
HKD1_k127_2012595_18 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008757 264.0
HKD1_k127_2012595_19 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001688 270.0
HKD1_k127_2012595_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.617e-229 719.0
HKD1_k127_2012595_20 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 261.0
HKD1_k127_2012595_21 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.0000000000000000000000000000000000000000000000000000000000000000001559 250.0
HKD1_k127_2012595_22 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000005332 201.0
HKD1_k127_2012595_23 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000009697 207.0
HKD1_k127_2012595_24 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000005929 210.0
HKD1_k127_2012595_25 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000008005 185.0
HKD1_k127_2012595_26 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000001441 184.0
HKD1_k127_2012595_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000692 152.0
HKD1_k127_2012595_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003914 133.0
HKD1_k127_2012595_29 YhhN family - - - 0.00000000000000000000000003273 116.0
HKD1_k127_2012595_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.188e-223 699.0
HKD1_k127_2012595_30 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000006594 110.0
HKD1_k127_2012595_31 Polymer-forming cytoskeletal - - - 0.0000000000000000000000561 104.0
HKD1_k127_2012595_32 - - - - 0.000000000000000000004524 96.0
HKD1_k127_2012595_33 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000001761 89.0
HKD1_k127_2012595_34 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000009582 79.0
HKD1_k127_2012595_35 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000005779 75.0
HKD1_k127_2012595_36 Tetratricopeptide repeats - - - 0.0000005351 61.0
HKD1_k127_2012595_37 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000008271 54.0
HKD1_k127_2012595_38 Domain of unknown function (DUF4124) - - - 0.000001979 57.0
HKD1_k127_2012595_39 Pfam:DUF1049 - - - 0.0000205 50.0
HKD1_k127_2012595_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 548.0
HKD1_k127_2012595_40 Domain of unknown function (DUF4124) - - - 0.0003118 51.0
HKD1_k127_2012595_5 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 505.0
HKD1_k127_2012595_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 488.0
HKD1_k127_2012595_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 486.0
HKD1_k127_2012595_8 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 469.0
HKD1_k127_2012595_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 367.0
HKD1_k127_201665_0 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 3.738e-220 692.0
HKD1_k127_201665_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 481.0
HKD1_k127_201665_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000004202 191.0
HKD1_k127_2051040_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.726e-247 781.0
HKD1_k127_2051040_1 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 390.0
HKD1_k127_2051040_2 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 374.0
HKD1_k127_2051040_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 344.0
HKD1_k127_2051040_4 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 318.0
HKD1_k127_2051040_5 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 316.0
HKD1_k127_2051040_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 309.0
HKD1_k127_2051040_7 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000001503 244.0
HKD1_k127_2051040_8 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000007617 198.0
HKD1_k127_2051040_9 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000001965 175.0
HKD1_k127_210558_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 5.09e-244 767.0
HKD1_k127_210558_1 DNA polymerase family A - - - 3.443e-213 677.0
HKD1_k127_210558_10 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000002046 222.0
HKD1_k127_210558_11 - - - - 0.000000000000000000000000000000000000000000000000000000009281 204.0
HKD1_k127_210558_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000005932 176.0
HKD1_k127_210558_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.00000000000000000000000000000000000000000000003937 173.0
HKD1_k127_210558_14 Pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.000000000000000000000000000000000000001664 148.0
HKD1_k127_210558_15 YbaB/EbfC DNA-binding family K09747 - - 0.000000000000000000000000000000000000004365 147.0
HKD1_k127_210558_16 Thioredoxin-like - - - 0.000000000000000000000005296 108.0
HKD1_k127_210558_17 Lipocalin-like domain - - - 0.0000000000000000000001796 106.0
HKD1_k127_210558_18 - - - - 0.0000000000000004836 85.0
HKD1_k127_210558_19 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.0000000000004212 68.0
HKD1_k127_210558_2 Phage terminase large subunit (GpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 522.0
HKD1_k127_210558_20 Helix-turn-helix domain - - - 0.00000004086 60.0
HKD1_k127_210558_23 PFAM IstB domain protein ATP-binding protein - - - 0.000006093 48.0
HKD1_k127_210558_24 - - - - 0.00001278 53.0
HKD1_k127_210558_25 chloride channel K03281 - - 0.00004127 47.0
HKD1_k127_210558_26 Phage integrase family - - - 0.0004335 46.0
HKD1_k127_210558_3 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 462.0
HKD1_k127_210558_4 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 464.0
HKD1_k127_210558_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 462.0
HKD1_k127_210558_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 410.0
HKD1_k127_210558_7 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 387.0
HKD1_k127_210558_8 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 317.0
HKD1_k127_210558_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007383 264.0
HKD1_k127_2136116_0 AMP-binding enzyme K01897 - 6.2.1.3 3.844e-212 676.0
HKD1_k127_2136116_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.593e-201 637.0
HKD1_k127_2136116_10 PFAM acyl-CoA dehydrogenase domain protein K00249,K11731 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 445.0
HKD1_k127_2136116_11 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 465.0
HKD1_k127_2136116_12 Terminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 421.0
HKD1_k127_2136116_13 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 412.0
HKD1_k127_2136116_14 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 398.0
HKD1_k127_2136116_15 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 400.0
HKD1_k127_2136116_16 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 394.0
HKD1_k127_2136116_17 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 397.0
HKD1_k127_2136116_18 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 374.0
HKD1_k127_2136116_19 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 360.0
HKD1_k127_2136116_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 2.641e-196 631.0
HKD1_k127_2136116_20 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 355.0
HKD1_k127_2136116_21 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 344.0
HKD1_k127_2136116_22 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
HKD1_k127_2136116_23 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 328.0
HKD1_k127_2136116_24 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 305.0
HKD1_k127_2136116_25 PFAM Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 303.0
HKD1_k127_2136116_26 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 292.0
HKD1_k127_2136116_27 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 297.0
HKD1_k127_2136116_28 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001201 273.0
HKD1_k127_2136116_29 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000435 261.0
HKD1_k127_2136116_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 564.0
HKD1_k127_2136116_30 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005272 253.0
HKD1_k127_2136116_31 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000003947 245.0
HKD1_k127_2136116_32 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000005737 237.0
HKD1_k127_2136116_33 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000004797 248.0
HKD1_k127_2136116_34 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000001064 227.0
HKD1_k127_2136116_35 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000001984 196.0
HKD1_k127_2136116_36 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000004308 177.0
HKD1_k127_2136116_37 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000004926 180.0
HKD1_k127_2136116_38 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000003538 174.0
HKD1_k127_2136116_39 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000002468 162.0
HKD1_k127_2136116_4 Aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 523.0
HKD1_k127_2136116_40 MaoC like domain - - - 0.00000000000000000000000000000000000000008843 157.0
HKD1_k127_2136116_41 binding domain protein - - - 0.000000000000000000000000000000000003577 147.0
HKD1_k127_2136116_42 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000002701 149.0
HKD1_k127_2136116_43 Histidine phosphatase superfamily (branch 1) K08296 - - 0.0000000000000000000000000000000002165 137.0
HKD1_k127_2136116_44 RNA recognition motif - - - 0.000000000000000000000000000002135 124.0
HKD1_k127_2136116_45 Thiamine-binding protein - - - 0.0000000000000000000000000003894 116.0
HKD1_k127_2136116_46 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000009488 124.0
HKD1_k127_2136116_47 - - - - 0.000000000000000000000000002914 115.0
HKD1_k127_2136116_48 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000001505 109.0
HKD1_k127_2136116_5 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 509.0
HKD1_k127_2136116_50 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000368 102.0
HKD1_k127_2136116_51 Glycosyl transferase, family 2 - - - 0.000000000000000001408 98.0
HKD1_k127_2136116_52 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.000000000001434 78.0
HKD1_k127_2136116_54 Belongs to the 'phage' integrase family - - - 0.000000007994 61.0
HKD1_k127_2136116_57 PilZ domain K03406 - - 0.00005384 51.0
HKD1_k127_2136116_59 Probable zinc-ribbon domain - - - 0.0002316 45.0
HKD1_k127_2136116_6 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 505.0
HKD1_k127_2136116_60 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0004793 45.0
HKD1_k127_2136116_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 510.0
HKD1_k127_2136116_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 494.0
HKD1_k127_2136116_9 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 491.0
HKD1_k127_2156762_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 570.0
HKD1_k127_2156762_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 449.0
HKD1_k127_2156762_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 391.0
HKD1_k127_2156762_3 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 388.0
HKD1_k127_2156762_4 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 342.0
HKD1_k127_2156762_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 315.0
HKD1_k127_2156762_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000024 168.0
HKD1_k127_2156762_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000008043 160.0
HKD1_k127_2156762_8 - - - - 0.00000000000000001431 88.0
HKD1_k127_2156762_9 PFAM asparagine synthase K06864 - - 0.00000000001826 65.0
HKD1_k127_2167066_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 8.383e-213 670.0
HKD1_k127_2167066_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 503.0
HKD1_k127_2167066_3 Glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000004564 246.0
HKD1_k127_2167066_4 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000007589 190.0
HKD1_k127_2167066_5 Belongs to the P(II) protein family K04751 - - 0.000000000000001798 76.0
HKD1_k127_2197804_0 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 349.0
HKD1_k127_2197804_1 GAF domain K01768 - 4.6.1.1 0.0000000000000000000000000000004487 128.0
HKD1_k127_2204135_0 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 403.0
HKD1_k127_2204135_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 309.0
HKD1_k127_2204135_2 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000006778 265.0
HKD1_k127_2204135_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000002688 125.0
HKD1_k127_2204135_4 Lipopolysaccharide-assembly - - - 0.0000000002111 68.0
HKD1_k127_2220612_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 424.0
HKD1_k127_2220612_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 350.0
HKD1_k127_2220612_2 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000002909 198.0
HKD1_k127_2226457_0 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 429.0
HKD1_k127_2226457_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 394.0
HKD1_k127_2226457_2 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 317.0
HKD1_k127_2226457_3 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 294.0
HKD1_k127_2226457_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 276.0
HKD1_k127_2226457_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007804 251.0
HKD1_k127_2226457_6 Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000006175 239.0
HKD1_k127_2226457_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000202 154.0
HKD1_k127_2226457_8 - - - - 0.0000000000000000000000000005115 122.0
HKD1_k127_2226457_9 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000001905 74.0
HKD1_k127_2233733_0 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000002517 209.0
HKD1_k127_2233733_1 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000001638 172.0
HKD1_k127_2233733_2 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000001136 139.0
HKD1_k127_2233733_3 GUN4-like - - - 0.000000000000000003233 89.0
HKD1_k127_2267306_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 370.0
HKD1_k127_2267306_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000008122 233.0
HKD1_k127_2267306_10 Protein of unknown function (DUF1018) - - - 0.0008164 48.0
HKD1_k127_2267306_2 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001052 236.0
HKD1_k127_2267306_3 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000001493 214.0
HKD1_k127_2267306_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000001069 144.0
HKD1_k127_2267306_5 nitrite reductase (NAD(P)H) large subunit K00362 - 1.7.1.15 0.00000000000000000000000000000000001093 139.0
HKD1_k127_2267306_6 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.000000000000000000000000000000000025 136.0
HKD1_k127_2267306_7 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000004021 135.0
HKD1_k127_2267306_8 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000001469 147.0
HKD1_k127_2267306_9 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000003057 134.0
HKD1_k127_2282577_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000003016 162.0
HKD1_k127_2282577_1 iron ion binding - - - 0.000000000000000004181 87.0
HKD1_k127_2282577_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000009533 63.0
HKD1_k127_2282577_3 - - - - 0.0000000001314 67.0
HKD1_k127_228712_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 511.0
HKD1_k127_228712_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 479.0
HKD1_k127_228712_10 Poly-gamma-glutamate hydrolase - - - 0.00000000000000000000000000000000000000000001021 169.0
HKD1_k127_228712_11 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000005608 145.0
HKD1_k127_228712_12 PFAM Class I peptide chain release factor - - - 0.000000000000000000000000000000000003817 141.0
HKD1_k127_228712_13 TatD related DNase K03424 - - 0.00000000000000000000000000000007955 133.0
HKD1_k127_228712_14 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000002703 125.0
HKD1_k127_228712_15 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000004085 110.0
HKD1_k127_228712_16 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000163 88.0
HKD1_k127_228712_17 Domain of unknown function (DUF4410) - - - 0.00006845 52.0
HKD1_k127_228712_19 SPW repeat - - - 0.0005623 44.0
HKD1_k127_228712_2 Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 476.0
HKD1_k127_228712_3 Rhodanese Homology Domain K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 475.0
HKD1_k127_228712_4 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 456.0
HKD1_k127_228712_5 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 412.0
HKD1_k127_228712_6 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 386.0
HKD1_k127_228712_7 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
HKD1_k127_228712_8 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000713 263.0
HKD1_k127_228712_9 HD domain K07023 - - 0.00000000000000000000000000000000000000000000002256 177.0
HKD1_k127_2296444_0 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006918 268.0
HKD1_k127_2296444_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001759 262.0
HKD1_k127_2296444_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004886 269.0
HKD1_k127_2296444_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000002869 233.0
HKD1_k127_2296444_4 ABC transporter K01996 - - 0.0000000000000000000001428 98.0
HKD1_k127_2296444_5 Receptor family ligand binding region K01999 - - 0.00000000000000001053 87.0
HKD1_k127_2296444_6 Receptor family ligand binding region K01999 - - 0.0001659 47.0
HKD1_k127_2328571_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 422.0
HKD1_k127_2328571_1 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 320.0
HKD1_k127_2328571_2 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000006899 192.0
HKD1_k127_2328571_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00001148 48.0
HKD1_k127_2330934_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K12955 - 3.6.3.6 0.0 1092.0
HKD1_k127_2330934_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 612.0
HKD1_k127_2330934_10 Responsible for energy coupling to the transport system K16784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 329.0
HKD1_k127_2330934_11 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 321.0
HKD1_k127_2330934_12 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000009766 237.0
HKD1_k127_2330934_13 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002366 239.0
HKD1_k127_2330934_14 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
HKD1_k127_2330934_15 ISXO2-like transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001578 227.0
HKD1_k127_2330934_16 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000000000002885 209.0
HKD1_k127_2330934_17 BioY family K03523 - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
HKD1_k127_2330934_18 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000004081 209.0
HKD1_k127_2330934_19 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000002323 161.0
HKD1_k127_2330934_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 523.0
HKD1_k127_2330934_20 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000001352 151.0
HKD1_k127_2330934_21 Rubrerythrin - - - 0.000000000000000000000000000003046 121.0
HKD1_k127_2330934_22 Cobalt transport protein K16783,K16785 - - 0.00000000000000000000000000004326 127.0
HKD1_k127_2330934_23 amidohydrolase - - - 0.00000000000000000000000000004581 127.0
HKD1_k127_2330934_24 PFAM membrane protein of K08972 - - 0.000000000000000000000000002058 115.0
HKD1_k127_2330934_25 DsrE/DsrF-like family - - - 0.0000000000000000000000002797 109.0
HKD1_k127_2330934_26 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000009477 106.0
HKD1_k127_2330934_28 pilus assembly protein PilW K02459 - - 0.0000000000000000003095 97.0
HKD1_k127_2330934_29 Domain of unknown function (DUF362) - - - 0.00000000000000001782 84.0
HKD1_k127_2330934_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 492.0
HKD1_k127_2330934_30 type IV pilus modification protein PilV K02458 - - 0.0000000000000004137 85.0
HKD1_k127_2330934_31 DsrE/DsrF-like family - - - 0.000000000000641 69.0
HKD1_k127_2330934_32 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000002221 66.0
HKD1_k127_2330934_33 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.000000000347 66.0
HKD1_k127_2330934_34 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.0000000003991 69.0
HKD1_k127_2330934_36 general secretion pathway protein - - - 0.00000002683 62.0
HKD1_k127_2330934_37 PFAM Fimbrial assembly family protein K02461 - - 0.00000003406 66.0
HKD1_k127_2330934_38 - - - - 0.000001714 59.0
HKD1_k127_2330934_39 Sulfite exporter TauE/SafE K07090 - - 0.0005555 44.0
HKD1_k127_2330934_4 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 449.0
HKD1_k127_2330934_5 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 421.0
HKD1_k127_2330934_6 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 419.0
HKD1_k127_2330934_7 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 379.0
HKD1_k127_2330934_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 366.0
HKD1_k127_2330934_9 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 371.0
HKD1_k127_2352349_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.299e-219 693.0
HKD1_k127_2352349_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 494.0
HKD1_k127_2352349_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 413.0
HKD1_k127_2352349_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 407.0
HKD1_k127_2352349_4 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 334.0
HKD1_k127_2352349_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004936 263.0
HKD1_k127_2352349_6 - - - - 0.0000000108 56.0
HKD1_k127_2352349_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000005093 59.0
HKD1_k127_2353088_0 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 349.0
HKD1_k127_2353088_1 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000005723 214.0
HKD1_k127_2353088_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003604 173.0
HKD1_k127_2353088_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000001394 165.0
HKD1_k127_2353088_4 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.000000000000000000000000000000000000001744 154.0
HKD1_k127_2353088_6 B12 binding domain K01849 - 5.4.99.2 0.000000000000006772 74.0
HKD1_k127_2353088_7 - - - - 0.00000000000001899 75.0
HKD1_k127_2368006_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.179e-195 626.0
HKD1_k127_2368006_1 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
HKD1_k127_2368006_2 aminopeptidase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000001939 137.0
HKD1_k127_2368006_3 Evidence 4 Homologs of previously reported genes of K03975 - - 0.000000000608 61.0
HKD1_k127_2368006_4 Evidence 4 Homologs of previously reported genes of K03975 - - 0.00000006489 53.0
HKD1_k127_2414694_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 1.094e-194 613.0
HKD1_k127_2414694_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 430.0
HKD1_k127_2414694_2 Cold shock protein K03704 - - 0.00000000000000000000000002725 108.0
HKD1_k127_2414694_3 radical SAM domain protein - - - 0.00000000001074 70.0
HKD1_k127_2439257_0 Alpha amylase, catalytic domain K00700,K01236 - 2.4.1.18,3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 543.0
HKD1_k127_2439257_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000001727 227.0
HKD1_k127_2505473_0 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 498.0
HKD1_k127_2505473_1 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 419.0
HKD1_k127_2505473_2 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 412.0
HKD1_k127_2505473_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 423.0
HKD1_k127_2505473_4 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 382.0
HKD1_k127_2505473_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 333.0
HKD1_k127_2505473_6 Peptidase family U32 - - - 0.00000000000000000000000000000000000000001669 158.0
HKD1_k127_2505473_7 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000574 117.0
HKD1_k127_2505473_8 - - - - 0.000005224 55.0
HKD1_k127_2624942_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 578.0
HKD1_k127_2624942_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000918 171.0
HKD1_k127_2624942_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000009791 136.0
HKD1_k127_2624942_3 Band 7 protein - - - 0.0000000000000001013 83.0
HKD1_k127_2624942_4 - - - - 0.000001603 56.0
HKD1_k127_2641311_0 AMP-binding enzyme K01897 - 6.2.1.3 1.224e-223 702.0
HKD1_k127_2641311_1 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 444.0
HKD1_k127_2641311_2 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 430.0
HKD1_k127_2641311_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 372.0
HKD1_k127_2641311_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 372.0
HKD1_k127_2641311_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004932 238.0
HKD1_k127_2641311_6 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000002775 96.0
HKD1_k127_2641311_7 - - - - 0.00004455 53.0
HKD1_k127_2647210_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 7.342e-196 617.0
HKD1_k127_2647210_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 600.0
HKD1_k127_2647210_10 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000037 229.0
HKD1_k127_2647210_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
HKD1_k127_2647210_12 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000001203 198.0
HKD1_k127_2647210_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000001759 160.0
HKD1_k127_2647210_14 NusB family K03625 - - 0.00000000000000000000000000000000000001978 149.0
HKD1_k127_2647210_15 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000008163 131.0
HKD1_k127_2647210_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000005611 111.0
HKD1_k127_2647210_17 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000008089 96.0
HKD1_k127_2647210_18 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.0000000000000000001944 90.0
HKD1_k127_2647210_19 Cytosol aminopeptidase family, N-terminal domain - - - 0.00000009592 61.0
HKD1_k127_2647210_2 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 571.0
HKD1_k127_2647210_3 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 480.0
HKD1_k127_2647210_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 404.0
HKD1_k127_2647210_5 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 386.0
HKD1_k127_2647210_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 379.0
HKD1_k127_2647210_7 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 304.0
HKD1_k127_2647210_8 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
HKD1_k127_2647210_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000315 235.0
HKD1_k127_2653955_0 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 598.0
HKD1_k127_2653955_1 CoA binding domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 584.0
HKD1_k127_2653955_10 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000009846 205.0
HKD1_k127_2653955_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000185 190.0
HKD1_k127_2653955_12 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000000000000000000000000000000000000002609 158.0
HKD1_k127_2653955_13 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000004809 141.0
HKD1_k127_2653955_14 Cytochrome c K19713 - 1.8.2.2 0.0000000000000000000000005105 109.0
HKD1_k127_2653955_15 - - - - 0.0000000000000000002017 102.0
HKD1_k127_2653955_16 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000006313 62.0
HKD1_k127_2653955_2 Metallo-beta-lactamase domain protein K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 527.0
HKD1_k127_2653955_3 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 468.0
HKD1_k127_2653955_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 359.0
HKD1_k127_2653955_5 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 312.0
HKD1_k127_2653955_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 293.0
HKD1_k127_2653955_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HKD1_k127_2653955_8 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000004729 237.0
HKD1_k127_2653955_9 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) K03386,K13279 GO:0000122,GO:0000187,GO:0000302,GO:0000303,GO:0000305,GO:0001775,GO:0001932,GO:0001934,GO:0002237,GO:0002252,GO:0002376,GO:0002520,GO:0002532,GO:0002536,GO:0002679,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002831,GO:0002832,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0006801,GO:0006950,GO:0006952,GO:0006954,GO:0006979,GO:0007162,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008283,GO:0008340,GO:0008379,GO:0008430,GO:0009056,GO:0009266,GO:0009408,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010259,GO:0010286,GO:0010310,GO:0010468,GO:0010556,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019430,GO:0022407,GO:0022408,GO:0023051,GO:0023056,GO:0023057,GO:0030155,GO:0030193,GO:0030194,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031401,GO:0031664,GO:0031665,GO:0032088,GO:0032101,GO:0032102,GO:0032147,GO:0032268,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032943,GO:0033554,GO:0033674,GO:0033993,GO:0034599,GO:0034614,GO:0042098,GO:0042110,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042542,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043207,GO:0043209,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043433,GO:0043523,GO:0043524,GO:0043549,GO:0043900,GO:0043901,GO:0044092,GO:0044093,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0045580,GO:0045581,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0045730,GO:0045859,GO:0045860,GO:0045892,GO:0045934,GO:0045937,GO:0046649,GO:0046651,GO:0046677,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048538,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0048872,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050878,GO:0050896,GO:0051090,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051186,GO:0051187,GO:0051193,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051338,GO:0051347,GO:0051704,GO:0051707,GO:0051716,GO:0051920,GO:0055114,GO:0060255,GO:0060548,GO:0061041,GO:0065007,GO:0065008,GO:0065009,GO:0070661,GO:0070887,GO:0071450,GO:0071451,GO:0071900,GO:0071902,GO:0072593,GO:0080090,GO:0080134,GO:0090303,GO:0097237,GO:0098754,GO:0098869,GO:1900046,GO:1900048,GO:1901099,GO:1901214,GO:1901215,GO:1901700,GO:1901701,GO:1902105,GO:1902106,GO:1902531,GO:1902533,GO:1902679,GO:1903034,GO:1903036,GO:1903037,GO:1903038,GO:1903506,GO:1903507,GO:1903706,GO:1903707,GO:1990748,GO:2000026,GO:2000112,GO:2000113,GO:2000377,GO:2000378,GO:2001141,GO:2001233,GO:2001234,GO:2001236,GO:2001237,GO:2001239,GO:2001240 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
HKD1_k127_2737_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 1.932e-290 902.0
HKD1_k127_2737_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 6.602e-262 811.0
HKD1_k127_2737_10 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000005021 244.0
HKD1_k127_2737_11 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009217 250.0
HKD1_k127_2737_12 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000004976 240.0
HKD1_k127_2737_13 - - - - 0.0000000000000000000000000000000000000000000000000000000009484 206.0
HKD1_k127_2737_14 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000000000000000001028 160.0
HKD1_k127_2737_15 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000009182 158.0
HKD1_k127_2737_16 FecR protein - - - 0.00000000000000000000000000000000006566 138.0
HKD1_k127_2737_17 Domain of unknown function DUF120 K01091 - 3.1.3.18 0.000000000000000000000007303 105.0
HKD1_k127_2737_18 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.000000000000000004033 86.0
HKD1_k127_2737_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 1.996e-249 776.0
HKD1_k127_2737_3 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 547.0
HKD1_k127_2737_4 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 549.0
HKD1_k127_2737_5 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 381.0
HKD1_k127_2737_6 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 340.0
HKD1_k127_2737_7 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 308.0
HKD1_k127_2737_8 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 314.0
HKD1_k127_2737_9 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 288.0
HKD1_k127_282927_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 510.0
HKD1_k127_282927_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 451.0
HKD1_k127_282927_2 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 392.0
HKD1_k127_282927_3 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000003816 223.0
HKD1_k127_282927_4 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000001547 221.0
HKD1_k127_2832388_0 Serine aminopeptidase, S33 K06889,K07397 - - 0.00000000000000000000000000000000000000000002861 168.0
HKD1_k127_2832388_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000007767 161.0
HKD1_k127_2832388_2 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.00000002883 59.0
HKD1_k127_2832388_3 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000003925 58.0
HKD1_k127_29317_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 556.0
HKD1_k127_29317_1 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002813 271.0
HKD1_k127_29317_2 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000000001224 165.0
HKD1_k127_29317_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000001187 150.0
HKD1_k127_29317_4 ABC transporter K01996 - - 0.0000000000000002497 79.0
HKD1_k127_2955647_0 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
HKD1_k127_2955647_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000001503 132.0
HKD1_k127_2955647_2 Domain of unknown function (DUF4388) - - - 0.000000004841 61.0
HKD1_k127_2986059_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002265 278.0
HKD1_k127_2986059_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006607 243.0
HKD1_k127_2986059_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000001977 201.0
HKD1_k127_2986059_3 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000001746 181.0
HKD1_k127_2986059_4 phosphodiesterase 10A K18438 GO:0000166,GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0004118,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0010738,GO:0010752,GO:0010754,GO:0016020,GO:0016787,GO:0016788,GO:0017076,GO:0018130,GO:0019001,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0023051,GO:0023052,GO:0023057,GO:0030551,GO:0030552,GO:0030553,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0036477,GO:0042578,GO:0043025,GO:0043167,GO:0043168,GO:0043204,GO:0043949,GO:0043951,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044424,GO:0044444,GO:0044464,GO:0046058,GO:0046068,GO:0046069,GO:0046434,GO:0046483,GO:0046700,GO:0047555,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055086,GO:0065007,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:0097458,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902531,GO:1902532 3.1.4.17,3.1.4.35 0.00000000172 69.0
HKD1_k127_30058_0 FecR protein - - - 0.0 1219.0
HKD1_k127_30058_1 CHASE2 K01768 - 4.6.1.1 3.062e-240 764.0
HKD1_k127_30058_10 PFAM Thioredoxin K03671 - - 0.00000000000000000000003212 111.0
HKD1_k127_30058_11 AraC-like ligand binding domain - - - 0.0000000000000003509 81.0
HKD1_k127_30058_12 PFAM Bile acid sodium symporter K03325 - - 0.0007442 43.0
HKD1_k127_30058_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 430.0
HKD1_k127_30058_3 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002607 281.0
HKD1_k127_30058_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004443 271.0
HKD1_k127_30058_5 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007383 264.0
HKD1_k127_30058_6 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000005989 211.0
HKD1_k127_30058_7 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000002962 194.0
HKD1_k127_30058_8 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000004845 174.0
HKD1_k127_30058_9 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000001383 156.0
HKD1_k127_3018573_0 Alpha amylase, catalytic domain - - - 0.0 1432.0
HKD1_k127_3018573_1 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 575.0
HKD1_k127_3018573_10 Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 339.0
HKD1_k127_3018573_11 nitrite reductase (NAD(P)H) large subunit K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 294.0
HKD1_k127_3018573_12 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 287.0
HKD1_k127_3018573_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004258 285.0
HKD1_k127_3018573_14 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000002298 269.0
HKD1_k127_3018573_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001785 250.0
HKD1_k127_3018573_16 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000001544 242.0
HKD1_k127_3018573_17 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000001293 237.0
HKD1_k127_3018573_18 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000007911 232.0
HKD1_k127_3018573_19 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000001267 210.0
HKD1_k127_3018573_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 488.0
HKD1_k127_3018573_20 - - - - 0.000000000000000000000000000000000000000000000000005108 183.0
HKD1_k127_3018573_21 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000002314 176.0
HKD1_k127_3018573_22 HNH nucleases - - - 0.000000000000000000000000000000000000001045 150.0
HKD1_k127_3018573_23 Calcineurin-like phosphoesterase superfamily domain K03269 - 3.6.1.54 0.000000000000000000000000000000000000001148 157.0
HKD1_k127_3018573_24 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000005786 105.0
HKD1_k127_3018573_25 - - - - 0.00000000000000000000003926 101.0
HKD1_k127_3018573_26 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000002098 97.0
HKD1_k127_3018573_27 DNA-sulfur modification-associated - - - 0.0000000000000000001164 101.0
HKD1_k127_3018573_29 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000006907 86.0
HKD1_k127_3018573_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 474.0
HKD1_k127_3018573_4 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 412.0
HKD1_k127_3018573_5 Electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 402.0
HKD1_k127_3018573_6 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 375.0
HKD1_k127_3018573_7 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 381.0
HKD1_k127_3018573_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 352.0
HKD1_k127_3018573_9 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 340.0
HKD1_k127_3033201_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 367.0
HKD1_k127_3033201_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 332.0
HKD1_k127_3033201_10 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000001368 154.0
HKD1_k127_3033201_11 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000002712 149.0
HKD1_k127_3033201_12 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000004254 143.0
HKD1_k127_3033201_13 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000004354 94.0
HKD1_k127_3033201_2 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 337.0
HKD1_k127_3033201_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 326.0
HKD1_k127_3033201_4 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 284.0
HKD1_k127_3033201_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008738 266.0
HKD1_k127_3033201_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
HKD1_k127_3033201_7 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000009988 257.0
HKD1_k127_3033201_8 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000002008 210.0
HKD1_k127_3033201_9 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000004243 207.0
HKD1_k127_3039061_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 527.0
HKD1_k127_3039061_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 477.0
HKD1_k127_3039061_2 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 346.0
HKD1_k127_3039061_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008921 258.0
HKD1_k127_3039061_4 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000006926 191.0
HKD1_k127_3039061_5 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.00000000000001009 80.0
HKD1_k127_3039061_6 Isochorismatase family - - - 0.00000000001654 64.0
HKD1_k127_3039061_7 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.0000001609 59.0
HKD1_k127_3039061_8 Protein of unknown function DUF72 - - - 0.000003635 50.0
HKD1_k127_30513_0 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 395.0
HKD1_k127_30513_1 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 359.0
HKD1_k127_30513_10 lipolytic protein G-D-S-L family K20306 - - 0.000000000005988 77.0
HKD1_k127_30513_11 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000008953 62.0
HKD1_k127_30513_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 346.0
HKD1_k127_30513_3 asparagine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 349.0
HKD1_k127_30513_4 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 314.0
HKD1_k127_30513_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000001286 216.0
HKD1_k127_30513_6 - - - - 0.000000000000000000000000000000000000000000000008003 183.0
HKD1_k127_30513_7 PFAM response regulator receiver - - - 0.000000000000000000000000000001818 125.0
HKD1_k127_30513_8 TOBE domain - - - 0.0000000000000000008476 87.0
HKD1_k127_30513_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000001724 74.0
HKD1_k127_3091388_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0 1035.0
HKD1_k127_3091388_1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 7.372e-226 713.0
HKD1_k127_3091388_10 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 342.0
HKD1_k127_3091388_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 325.0
HKD1_k127_3091388_12 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000003697 227.0
HKD1_k127_3091388_13 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000008106 225.0
HKD1_k127_3091388_14 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000001357 221.0
HKD1_k127_3091388_15 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000107 207.0
HKD1_k127_3091388_16 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000004041 196.0
HKD1_k127_3091388_17 - - - - 0.000000000000000000000000000000000000000000007404 173.0
HKD1_k127_3091388_18 TPR Domain containing protein - - - 0.0000000000000000000000000000000000000001856 165.0
HKD1_k127_3091388_19 - - - - 0.0000000000000000000000007482 111.0
HKD1_k127_3091388_2 Molybdate transporter of MFS superfamily - - - 3.752e-196 617.0
HKD1_k127_3091388_20 Transcriptional regulator, LysR family K02019 - - 0.00000000000000000000003057 103.0
HKD1_k127_3091388_21 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000001014 110.0
HKD1_k127_3091388_22 radical SAM domain protein - - - 0.000000000000000000001526 95.0
HKD1_k127_3091388_25 pilus assembly protein major pilin PilA K02650,K02655 - - 0.0000000001273 68.0
HKD1_k127_3091388_26 ABC-2 family transporter protein - - - 0.00000005286 63.0
HKD1_k127_3091388_28 SNARE associated Golgi protein - - - 0.000003583 49.0
HKD1_k127_3091388_29 - - - - 0.000004417 56.0
HKD1_k127_3091388_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 558.0
HKD1_k127_3091388_30 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0005231 44.0
HKD1_k127_3091388_4 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 507.0
HKD1_k127_3091388_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 494.0
HKD1_k127_3091388_6 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 443.0
HKD1_k127_3091388_7 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 430.0
HKD1_k127_3091388_8 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 402.0
HKD1_k127_3091388_9 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 365.0
HKD1_k127_309239_0 Integrase core domain - - - 0.0000000000001097 83.0
HKD1_k127_309239_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000001182 74.0
HKD1_k127_309239_2 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0004888 47.0
HKD1_k127_3105663_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 375.0
HKD1_k127_3105663_1 Transglycosylase - - - 0.000000000000000000000000000000000000003072 148.0
HKD1_k127_3105663_2 HD domain - - - 0.00000000000000000000000000000000000001849 167.0
HKD1_k127_3105663_3 phosphorelay signal transduction system - - - 0.00000000000000000000003824 100.0
HKD1_k127_3105663_4 - - - - 0.00000001061 59.0
HKD1_k127_3105663_5 GGDEF domain K13069 - 2.7.7.65 0.000003432 61.0
HKD1_k127_3125956_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 7.974e-287 890.0
HKD1_k127_3125956_1 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000001164 87.0
HKD1_k127_3125956_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000001986 71.0
HKD1_k127_3125956_3 PIN domain K07063 - - 0.000000000155 67.0
HKD1_k127_3125956_4 nuclease activity K06218 - - 0.00003153 47.0
HKD1_k127_3130406_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 415.0
HKD1_k127_3130406_1 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 279.0
HKD1_k127_3130406_2 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008536 249.0
HKD1_k127_3130406_3 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000001379 192.0
HKD1_k127_3130406_4 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000001791 193.0
HKD1_k127_3130406_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000001538 168.0
HKD1_k127_3130406_6 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000142 127.0
HKD1_k127_3130406_7 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000005706 67.0
HKD1_k127_3144967_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1259.0
HKD1_k127_3144967_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 428.0
HKD1_k127_3144967_10 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000000001848 121.0
HKD1_k127_3144967_11 mRNA binding - - - 0.0000000000000000000000000004044 115.0
HKD1_k127_3144967_2 photosystem II stabilization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 426.0
HKD1_k127_3144967_3 COG1363 Cellulase M and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 386.0
HKD1_k127_3144967_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 353.0
HKD1_k127_3144967_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 307.0
HKD1_k127_3144967_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005396 252.0
HKD1_k127_3144967_7 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000004418 180.0
HKD1_k127_3144967_8 NTPase - - - 0.0000000000000000000000000000000000000000000001133 174.0
HKD1_k127_3144967_9 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000000000000004902 134.0
HKD1_k127_316094_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 297.0
HKD1_k127_316094_1 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000001475 91.0
HKD1_k127_316094_2 HEAT repeat - - - 0.000000006763 66.0
HKD1_k127_316094_4 Domain of unknown function (DUF4124) - - - 0.000417 49.0
HKD1_k127_3188842_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 360.0
HKD1_k127_3188842_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000144 283.0
HKD1_k127_3188842_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006283 275.0
HKD1_k127_3188842_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000001713 213.0
HKD1_k127_3188842_4 sequence-specific DNA binding K18830 - - 0.00000000000000000000000000000000000000000004904 163.0
HKD1_k127_3188842_5 Serine hydrolase involved in the detoxification of formaldehyde K03930,K17076 - - 0.0000000205 66.0
HKD1_k127_3188842_7 - - - - 0.00000006473 55.0
HKD1_k127_3213813_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 384.0
HKD1_k127_3213813_1 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005368 288.0
HKD1_k127_3213813_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000002962 246.0
HKD1_k127_3213813_3 PFAM Nitroreductase - - - 0.00000000000000000000000000003312 121.0
HKD1_k127_3213813_4 6-phospho-beta-galactosidase activity - - - 0.00000000000000001656 94.0
HKD1_k127_325083_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.804e-258 810.0
HKD1_k127_325083_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 444.0
HKD1_k127_325083_10 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000003418 104.0
HKD1_k127_325083_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000008586 86.0
HKD1_k127_325083_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000004089 80.0
HKD1_k127_325083_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 424.0
HKD1_k127_325083_3 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 365.0
HKD1_k127_325083_4 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 289.0
HKD1_k127_325083_5 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000001767 237.0
HKD1_k127_325083_6 tigr00255 - - - 0.000000000000000000000000000000000000000000000000000000000000001215 230.0
HKD1_k127_325083_7 ATPase associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000186 226.0
HKD1_k127_325083_8 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000002018 201.0
HKD1_k127_325083_9 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000001393 190.0
HKD1_k127_3251044_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 1.849e-246 766.0
HKD1_k127_3251044_1 Sigma-54 interaction domain K07714,K07715 - - 7.438e-222 695.0
HKD1_k127_3251044_10 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
HKD1_k127_3251044_11 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001302 269.0
HKD1_k127_3251044_12 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005263 246.0
HKD1_k127_3251044_13 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000000009704 249.0
HKD1_k127_3251044_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001603 238.0
HKD1_k127_3251044_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000002758 235.0
HKD1_k127_3251044_16 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000007608 223.0
HKD1_k127_3251044_17 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000005917 230.0
HKD1_k127_3251044_18 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000002418 181.0
HKD1_k127_3251044_19 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000003283 171.0
HKD1_k127_3251044_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 554.0
HKD1_k127_3251044_20 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000002754 156.0
HKD1_k127_3251044_21 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000009025 151.0
HKD1_k127_3251044_22 A G-specific K03575 - - 0.0000000000000000000000000000000000001081 143.0
HKD1_k127_3251044_23 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000001038 139.0
HKD1_k127_3251044_24 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000004886 123.0
HKD1_k127_3251044_25 Thioesterase - - - 0.0000000000000000000000000007772 117.0
HKD1_k127_3251044_26 nuclear chromosome segregation - - - 0.000000000000000000000000006653 121.0
HKD1_k127_3251044_27 PFAM Rubrerythrin - - - 0.000000000000000000000001949 108.0
HKD1_k127_3251044_28 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000001373 103.0
HKD1_k127_3251044_29 nuclear chromosome segregation - - - 0.0000000000000000001775 98.0
HKD1_k127_3251044_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 545.0
HKD1_k127_3251044_30 Acetyltransferase K03789 - 2.3.1.128 0.00000000000000003631 88.0
HKD1_k127_3251044_31 cheY-homologous receiver domain - - - 0.0000000000000009384 81.0
HKD1_k127_3251044_32 CDP-alcohol phosphatidyltransferase. Source PGD - - - 0.00000000000005274 78.0
HKD1_k127_3251044_33 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000001982 75.0
HKD1_k127_3251044_34 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate - - - 0.0000000006331 68.0
HKD1_k127_3251044_36 - - - - 0.000001756 53.0
HKD1_k127_3251044_37 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000001854 60.0
HKD1_k127_3251044_38 Protein of unknown function (DUF2723) - - - 0.00007283 48.0
HKD1_k127_3251044_4 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 539.0
HKD1_k127_3251044_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 527.0
HKD1_k127_3251044_6 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 485.0
HKD1_k127_3251044_7 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 409.0
HKD1_k127_3251044_8 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 403.0
HKD1_k127_3251044_9 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006178 280.0
HKD1_k127_3257885_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.979e-277 867.0
HKD1_k127_3257885_1 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 1.76e-270 856.0
HKD1_k127_3257885_10 PFAM formylmethanofuran dehydrogenase subunit E region K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000001154 203.0
HKD1_k127_3257885_11 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000006273 191.0
HKD1_k127_3257885_12 RNA methyltransferase K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000004941 179.0
HKD1_k127_3257885_13 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000005515 170.0
HKD1_k127_3257885_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.0000000000000000000000000000000000002778 147.0
HKD1_k127_3257885_15 translation initiation factor activity - - - 0.00000008492 63.0
HKD1_k127_3257885_2 Domain of unknown function (DUF3394) - - - 1.009e-257 811.0
HKD1_k127_3257885_3 Belongs to the ClpX chaperone family - - - 1.258e-213 679.0
HKD1_k127_3257885_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 526.0
HKD1_k127_3257885_5 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 374.0
HKD1_k127_3257885_6 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 362.0
HKD1_k127_3257885_7 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 331.0
HKD1_k127_3257885_8 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 301.0
HKD1_k127_3257885_9 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003774 288.0
HKD1_k127_3260181_0 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 537.0
HKD1_k127_3260181_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 450.0
HKD1_k127_3260181_10 PFAM Roadblock LC7 - - - 0.000000000000000000000000000000002014 134.0
HKD1_k127_3260181_11 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000006198 142.0
HKD1_k127_3260181_12 Tetratricopeptide repeats - - - 0.00000000000000000000007789 109.0
HKD1_k127_3260181_13 Pilus assembly protein, PilP K02665 - - 0.000000000000000000001472 102.0
HKD1_k127_3260181_14 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000001482 102.0
HKD1_k127_3260181_15 pilus assembly protein PilW K02672 - - 0.00000000000000001048 93.0
HKD1_k127_3260181_16 PFAM Fimbrial assembly K02663 - - 0.00000000000000004155 89.0
HKD1_k127_3260181_17 alginic acid biosynthetic process - - - 0.000000000000001386 88.0
HKD1_k127_3260181_18 Tetratricopeptide repeat - - - 0.00000000000007026 82.0
HKD1_k127_3260181_19 Prokaryotic N-terminal methylation motif K02671 - - 0.000000000006946 72.0
HKD1_k127_3260181_2 Neisseria PilC beta-propeller domain K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 430.0
HKD1_k127_3260181_20 pilus assembly protein PilW K02672 - - 0.0000000002494 69.0
HKD1_k127_3260181_21 type IV pilus modification protein PilV K02671 - - 0.000004553 55.0
HKD1_k127_3260181_22 PilX N-terminal - - - 0.000009741 57.0
HKD1_k127_3260181_23 Type II transport protein GspH K08084 - - 0.0001658 50.0
HKD1_k127_3260181_3 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 367.0
HKD1_k127_3260181_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 310.0
HKD1_k127_3260181_5 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002317 291.0
HKD1_k127_3260181_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003175 265.0
HKD1_k127_3260181_7 Ras family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009678 262.0
HKD1_k127_3260181_8 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000005655 254.0
HKD1_k127_3260181_9 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000001608 141.0
HKD1_k127_3270184_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.471e-301 936.0
HKD1_k127_3270184_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.737e-286 887.0
HKD1_k127_3270184_10 acetyl coenzyme A synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 301.0
HKD1_k127_3270184_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004217 274.0
HKD1_k127_3270184_12 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001542 250.0
HKD1_k127_3270184_13 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001801 240.0
HKD1_k127_3270184_14 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003222 243.0
HKD1_k127_3270184_15 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000001019 190.0
HKD1_k127_3270184_16 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000003073 162.0
HKD1_k127_3270184_17 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000003044 144.0
HKD1_k127_3270184_18 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000000000000000002602 134.0
HKD1_k127_3270184_19 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000002295 124.0
HKD1_k127_3270184_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.022e-273 849.0
HKD1_k127_3270184_20 Y_Y_Y domain - - - 0.000000000000000000000006147 114.0
HKD1_k127_3270184_21 - - - - 0.000000000000000000003555 106.0
HKD1_k127_3270184_22 - - - - 0.000001204 51.0
HKD1_k127_3270184_23 Peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.0001385 46.0
HKD1_k127_3270184_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 584.0
HKD1_k127_3270184_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 555.0
HKD1_k127_3270184_5 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 497.0
HKD1_k127_3270184_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
HKD1_k127_3270184_7 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 354.0
HKD1_k127_3270184_8 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 338.0
HKD1_k127_3270184_9 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 309.0
HKD1_k127_3284301_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 2.304e-241 762.0
HKD1_k127_3284301_1 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000005465 203.0
HKD1_k127_3284301_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000001844 177.0
HKD1_k127_3328228_0 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 7.429e-274 850.0
HKD1_k127_3328228_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 616.0
HKD1_k127_3328228_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 341.0
HKD1_k127_3328228_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 305.0
HKD1_k127_3328228_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 249.0
HKD1_k127_3328228_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000001014 229.0
HKD1_k127_3330642_0 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 403.0
HKD1_k127_3330642_1 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 392.0
HKD1_k127_3330642_11 Helix-turn-helix domain K07219 - - 0.0000315 50.0
HKD1_k127_3330642_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 340.0
HKD1_k127_3330642_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 327.0
HKD1_k127_3330642_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 324.0
HKD1_k127_3330642_5 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 330.0
HKD1_k127_3330642_6 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000002718 248.0
HKD1_k127_3330642_7 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000009079 208.0
HKD1_k127_3330642_8 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000002706 163.0
HKD1_k127_3330642_9 PFAM response regulator receiver - - - 0.00000000000000000000000003786 112.0
HKD1_k127_3331733_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 592.0
HKD1_k127_3331733_1 BFD-like [2Fe-2S] binding domain K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 499.0
HKD1_k127_3331733_10 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 312.0
HKD1_k127_3331733_11 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000001451 172.0
HKD1_k127_3331733_12 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000001029 167.0
HKD1_k127_3331733_13 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000023 173.0
HKD1_k127_3331733_14 GAF domain - - - 0.0000000000000000000000000000000000001746 165.0
HKD1_k127_3331733_15 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000006233 117.0
HKD1_k127_3331733_16 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000001581 111.0
HKD1_k127_3331733_17 SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000003637 108.0
HKD1_k127_3331733_18 PLD-like domain K17717 - 3.1.4.4 0.000000000000000006264 91.0
HKD1_k127_3331733_19 - - - - 0.000000003667 59.0
HKD1_k127_3331733_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 452.0
HKD1_k127_3331733_20 Tetratricopeptide repeat - - - 0.00001542 50.0
HKD1_k127_3331733_21 Resolvase, N terminal domain K07450 - - 0.00001817 49.0
HKD1_k127_3331733_23 Glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000395 46.0
HKD1_k127_3331733_24 ammonia-lyase activity K01745 - 4.3.1.3 0.00004733 48.0
HKD1_k127_3331733_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 452.0
HKD1_k127_3331733_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 394.0
HKD1_k127_3331733_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 374.0
HKD1_k127_3331733_6 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 350.0
HKD1_k127_3331733_7 peptidyl-tyrosine sulfation K03217,K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 355.0
HKD1_k127_3331733_8 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 349.0
HKD1_k127_3331733_9 ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 334.0
HKD1_k127_3336025_0 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 4.636e-208 649.0
HKD1_k127_3336025_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 489.0
HKD1_k127_3336025_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000002273 56.0
HKD1_k127_3345658_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004232 299.0
HKD1_k127_3345658_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000002034 71.0
HKD1_k127_3358588_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.286e-226 711.0
HKD1_k127_3358588_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 1.657e-210 659.0
HKD1_k127_3358588_10 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000004759 182.0
HKD1_k127_3358588_11 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000005411 186.0
HKD1_k127_3358588_12 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000008037 164.0
HKD1_k127_3358588_13 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000509 147.0
HKD1_k127_3358588_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000003502 124.0
HKD1_k127_3358588_15 Predicted membrane protein (DUF2231) - - - 0.000000000000000007164 89.0
HKD1_k127_3358588_16 Competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00000000000000006549 89.0
HKD1_k127_3358588_17 - - - - 0.0000000002642 66.0
HKD1_k127_3358588_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.866e-200 633.0
HKD1_k127_3358588_3 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 562.0
HKD1_k127_3358588_4 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 527.0
HKD1_k127_3358588_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 484.0
HKD1_k127_3358588_6 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 373.0
HKD1_k127_3358588_7 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 345.0
HKD1_k127_3358588_8 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 299.0
HKD1_k127_3358588_9 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000009477 228.0
HKD1_k127_3374064_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 539.0
HKD1_k127_3374064_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 476.0
HKD1_k127_3374064_2 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 353.0
HKD1_k127_3377302_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000146 260.0
HKD1_k127_3377302_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
HKD1_k127_3377302_2 HIT domain K02503 - - 0.0000000000000000000000000000000000000001313 153.0
HKD1_k127_3377302_3 PFAM TatD-related deoxyribonuclease K03424 - - 0.0000000000000000000000000000000004967 141.0
HKD1_k127_3377302_4 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000001422 124.0
HKD1_k127_3377302_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000002847 57.0
HKD1_k127_3379689_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 469.0
HKD1_k127_3379689_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 425.0
HKD1_k127_3379689_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 411.0
HKD1_k127_3379689_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 382.0
HKD1_k127_3379689_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 371.0
HKD1_k127_3379689_5 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.00000000000000000000000000000000000000008417 154.0
HKD1_k127_3379689_6 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000006685 148.0
HKD1_k127_3379689_7 PFAM Binding-protein-dependent transport K02033 - - 0.000000000000000000000000000103 116.0
HKD1_k127_3393203_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.03e-197 642.0
HKD1_k127_3393203_1 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 400.0
HKD1_k127_3393203_2 binding domain protein - - - 0.0000000000000000000000000001025 125.0
HKD1_k127_3393203_3 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000008812 119.0
HKD1_k127_3393203_4 aspartate kinase activity K00928,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000001448 92.0
HKD1_k127_3393203_5 - - - - 0.00000000000000002147 85.0
HKD1_k127_3393203_6 PFAM Bile acid sodium symporter K03453 - - 0.00000263 54.0
HKD1_k127_3400522_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 540.0
HKD1_k127_3400522_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001502 268.0
HKD1_k127_3400522_2 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009475 253.0
HKD1_k127_3400522_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000003701 117.0
HKD1_k127_3406407_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 308.0
HKD1_k127_3406407_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000007909 225.0
HKD1_k127_3406407_2 Major Facilitator Superfamily - - - 0.000001624 53.0
HKD1_k127_340800_0 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 564.0
HKD1_k127_340800_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 543.0
HKD1_k127_340800_10 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000005863 214.0
HKD1_k127_340800_11 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000001863 196.0
HKD1_k127_340800_12 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000005511 197.0
HKD1_k127_340800_13 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000002805 188.0
HKD1_k127_340800_14 spore germination K16928 - - 0.000000000000000000000000000000000000000000000000007476 190.0
HKD1_k127_340800_15 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.00000000000000000000006187 108.0
HKD1_k127_340800_16 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.00000000000000002737 81.0
HKD1_k127_340800_17 cheY-homologous receiver domain - - - 0.000000000000004912 80.0
HKD1_k127_340800_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 426.0
HKD1_k127_340800_3 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 409.0
HKD1_k127_340800_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 428.0
HKD1_k127_340800_5 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 353.0
HKD1_k127_340800_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 324.0
HKD1_k127_340800_7 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006872 293.0
HKD1_k127_340800_8 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001629 282.0
HKD1_k127_340800_9 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002366 239.0
HKD1_k127_3408901_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 609.0
HKD1_k127_3408901_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 608.0
HKD1_k127_3408901_10 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 302.0
HKD1_k127_3408901_11 ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000003194 235.0
HKD1_k127_3408901_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000232 189.0
HKD1_k127_3408901_13 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000703 170.0
HKD1_k127_3408901_14 PTS system fructose IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000000000001383 149.0
HKD1_k127_3408901_15 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000001467 142.0
HKD1_k127_3408901_16 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000744 136.0
HKD1_k127_3408901_17 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000000001617 122.0
HKD1_k127_3408901_18 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000001641 119.0
HKD1_k127_3408901_19 PAC2 family - - - 0.0000006275 54.0
HKD1_k127_3408901_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 603.0
HKD1_k127_3408901_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 590.0
HKD1_k127_3408901_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 548.0
HKD1_k127_3408901_5 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 519.0
HKD1_k127_3408901_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 437.0
HKD1_k127_3408901_7 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 413.0
HKD1_k127_3408901_8 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 362.0
HKD1_k127_3408901_9 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 310.0
HKD1_k127_3409783_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1100.0
HKD1_k127_3409783_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.278e-198 625.0
HKD1_k127_3409783_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003409 282.0
HKD1_k127_3409783_11 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 267.0
HKD1_k127_3409783_12 Glycosyltransferase family 17 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005184 259.0
HKD1_k127_3409783_13 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000001035 246.0
HKD1_k127_3409783_14 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000000000000000000000000000000007328 148.0
HKD1_k127_3409783_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002447 132.0
HKD1_k127_3409783_16 Dodecin K09165 - - 0.0000000000000000000005317 97.0
HKD1_k127_3409783_17 Methionine biosynthesis protein MetW - - - 0.000000000000003418 83.0
HKD1_k127_3409783_18 PFAM Methyltransferase type 11 - - - 0.000000000006871 74.0
HKD1_k127_3409783_19 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000001781 58.0
HKD1_k127_3409783_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 611.0
HKD1_k127_3409783_20 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.0001022 54.0
HKD1_k127_3409783_3 membrane protein involved in D-alanine export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 584.0
HKD1_k127_3409783_4 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 523.0
HKD1_k127_3409783_5 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 402.0
HKD1_k127_3409783_6 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 367.0
HKD1_k127_3409783_7 glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 326.0
HKD1_k127_3409783_8 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 320.0
HKD1_k127_3409783_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 312.0
HKD1_k127_34389_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002064 271.0
HKD1_k127_34389_1 Ras family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002159 259.0
HKD1_k127_34389_2 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000006153 251.0
HKD1_k127_34389_3 PFAM Roadblock LC7 - - - 0.000000000000000000000000000000002647 134.0
HKD1_k127_3441940_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.275e-306 958.0
HKD1_k127_3441940_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 502.0
HKD1_k127_3441940_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 320.0
HKD1_k127_3441940_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000001261 178.0
HKD1_k127_3441940_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000006743 69.0
HKD1_k127_3455928_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.534e-199 648.0
HKD1_k127_3455928_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 602.0
HKD1_k127_3455928_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 344.0
HKD1_k127_3455928_3 ACT domain K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 349.0
HKD1_k127_3455928_4 PFAM Bile acid sodium symporter K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002092 249.0
HKD1_k127_3455928_5 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000002224 189.0
HKD1_k127_3455928_6 PIN domain - - - 0.00000000000004565 78.0
HKD1_k127_3455928_7 Transcriptional regulator, AbrB family - - - 0.000000000009485 69.0
HKD1_k127_3468254_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1647.0
HKD1_k127_3468254_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 420.0
HKD1_k127_3468254_10 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000002099 81.0
HKD1_k127_3468254_11 - - - - 0.00000000000001568 80.0
HKD1_k127_3468254_12 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.0000000003857 62.0
HKD1_k127_3468254_13 Domain of unknown function (DUF4124) - - - 0.0003385 50.0
HKD1_k127_3468254_2 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 375.0
HKD1_k127_3468254_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 333.0
HKD1_k127_3468254_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 301.0
HKD1_k127_3468254_5 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000002967 186.0
HKD1_k127_3468254_6 Sodium hydrogen exchanger - - - 0.000000000000000000000000008168 124.0
HKD1_k127_3468254_7 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.00000000000000000000000001075 113.0
HKD1_k127_3468254_8 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000001587 96.0
HKD1_k127_3468254_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000008798 87.0
HKD1_k127_3469095_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 364.0
HKD1_k127_3469095_1 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000002018 265.0
HKD1_k127_3469095_2 Oxidoreductase molybdopterin binding domain K07147 - - 0.00000000000000000000000000000000000000000000000003425 185.0
HKD1_k127_3469095_3 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.0000000000000000000000000000000000000001299 156.0
HKD1_k127_3469095_4 - - - - 0.0000001919 57.0
HKD1_k127_3475831_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 335.0
HKD1_k127_3475831_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000006967 155.0
HKD1_k127_3475831_2 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000001016 146.0
HKD1_k127_3475831_3 bacterial-type flagellum-dependent cell motility - - - 0.00000000000001612 86.0
HKD1_k127_3485734_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1357.0
HKD1_k127_3485734_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 450.0
HKD1_k127_3485734_10 cheY-homologous receiver domain - - - 0.000002197 54.0
HKD1_k127_3485734_11 - - - - 0.00003865 49.0
HKD1_k127_3485734_2 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 409.0
HKD1_k127_3485734_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 355.0
HKD1_k127_3485734_4 outer membrane efflux - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 320.0
HKD1_k127_3485734_5 Psort location Cytoplasmic, score K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000003259 245.0
HKD1_k127_3485734_6 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000003541 128.0
HKD1_k127_3485734_7 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000009582 79.0
HKD1_k127_3485734_8 - - - - 0.000000000000003576 77.0
HKD1_k127_3506929_0 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000001933 188.0
HKD1_k127_3506929_1 Forkhead associated domain - - - 0.000000000000000000000001968 115.0
HKD1_k127_3506929_2 - - - - 0.00000000000000000000002423 109.0
HKD1_k127_3525436_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000002686 249.0
HKD1_k127_3525436_1 PFAM Bacterial regulatory proteins, gntR family - - - 0.00000000000000000000000000000000000000000000000000001739 198.0
HKD1_k127_3525436_2 - - - - 0.000000000000000000000000000000000000000000000001762 176.0
HKD1_k127_3525436_3 Haem-degrading - - - 0.0000000000000000000000000004128 120.0
HKD1_k127_3525436_4 Nitroreductase family - - - 0.0000000000000000000002164 97.0
HKD1_k127_353224_0 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 343.0
HKD1_k127_353224_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 314.0
HKD1_k127_353224_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005504 265.0
HKD1_k127_353224_3 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000002771 183.0
HKD1_k127_353224_4 - - - - 0.00000000000000000000000000000003481 138.0
HKD1_k127_353224_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000007935 104.0
HKD1_k127_353224_6 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000007366 93.0
HKD1_k127_353224_7 regulatory protein, FmdB family - - - 0.0000000000000002567 80.0
HKD1_k127_353224_8 AAA domain K07028 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 - 0.0000008651 59.0
HKD1_k127_3561998_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.712e-303 953.0
HKD1_k127_3561998_1 Required for chromosome condensation and partitioning K03529 - - 2.304e-211 699.0
HKD1_k127_3561998_10 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
HKD1_k127_3561998_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000004625 172.0
HKD1_k127_3561998_12 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000002503 125.0
HKD1_k127_3561998_13 Competence-damaged protein K03743 - 3.5.1.42 0.000000000000000000000001436 106.0
HKD1_k127_3561998_2 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 593.0
HKD1_k127_3561998_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 547.0
HKD1_k127_3561998_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 509.0
HKD1_k127_3561998_5 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 496.0
HKD1_k127_3561998_6 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 338.0
HKD1_k127_3561998_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 335.0
HKD1_k127_3561998_8 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 325.0
HKD1_k127_3561998_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001567 274.0
HKD1_k127_35732_0 Glycosyl hydrolases family 15 - - - 9.344e-197 627.0
HKD1_k127_35732_1 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 598.0
HKD1_k127_35732_10 Protein of unknown function (DUF2769) - - - 0.000000000000004472 77.0
HKD1_k127_35732_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 386.0
HKD1_k127_35732_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 384.0
HKD1_k127_35732_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 383.0
HKD1_k127_35732_5 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000004356 220.0
HKD1_k127_35732_6 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000002411 162.0
HKD1_k127_35732_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000000002564 131.0
HKD1_k127_35732_8 Plasmid stabilization system K19092 - - 0.00000000000000000000000000000004779 129.0
HKD1_k127_35732_9 MjaI restriction endonuclease - - - 0.00000000000000004639 81.0
HKD1_k127_3584728_0 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 376.0
HKD1_k127_3584728_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 320.0
HKD1_k127_36558_0 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 513.0
HKD1_k127_36558_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 376.0
HKD1_k127_36558_10 Bacterial transferase hexapeptide (six repeats) K08280 - - 0.000000000000000000000000002128 119.0
HKD1_k127_36558_11 PFAM Tetratricopeptide - - - 0.00000000000000000000000003784 121.0
HKD1_k127_36558_12 Methyltransferase domain - - - 0.0000000000000000000000002 113.0
HKD1_k127_36558_13 energy transducer activity K03832,K08086 - - 0.000000000000000000000001782 113.0
HKD1_k127_36558_14 Methionine biosynthesis protein MetW - - - 0.0000000000000000002634 96.0
HKD1_k127_36558_15 Methyltransferase domain - - - 0.000000000000004287 83.0
HKD1_k127_36558_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000002416 67.0
HKD1_k127_36558_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 360.0
HKD1_k127_36558_3 PFAM DegT DnrJ EryC1 StrS aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 362.0
HKD1_k127_36558_4 PFAM Glycosyl transferase, group 1 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 293.0
HKD1_k127_36558_5 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
HKD1_k127_36558_6 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 266.0
HKD1_k127_36558_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
HKD1_k127_36558_8 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003316 258.0
HKD1_k127_36558_9 Thioesterase superfamily K07107 - - 0.0000000000000000000000000000002184 127.0
HKD1_k127_3725792_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1106.0
HKD1_k127_3725792_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 6.357e-232 743.0
HKD1_k127_3725792_10 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000361 261.0
HKD1_k127_3725792_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001063 244.0
HKD1_k127_3725792_12 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000002837 220.0
HKD1_k127_3725792_13 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000003802 216.0
HKD1_k127_3725792_14 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000002171 209.0
HKD1_k127_3725792_15 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000005508 190.0
HKD1_k127_3725792_16 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000001008 186.0
HKD1_k127_3725792_17 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000001208 172.0
HKD1_k127_3725792_18 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000001375 160.0
HKD1_k127_3725792_19 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000042 141.0
HKD1_k127_3725792_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 564.0
HKD1_k127_3725792_20 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000003548 140.0
HKD1_k127_3725792_21 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000003105 117.0
HKD1_k127_3725792_22 RNA polymerase-binding protein DksA K06204 - - 0.0000000000000000000000002327 111.0
HKD1_k127_3725792_23 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000008176 106.0
HKD1_k127_3725792_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 556.0
HKD1_k127_3725792_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 421.0
HKD1_k127_3725792_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 409.0
HKD1_k127_3725792_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 314.0
HKD1_k127_3725792_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 308.0
HKD1_k127_3725792_8 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 331.0
HKD1_k127_3725792_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 296.0
HKD1_k127_3775499_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 607.0
HKD1_k127_3775499_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 520.0
HKD1_k127_3775499_2 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000004396 214.0
HKD1_k127_380509_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 2.159e-215 676.0
HKD1_k127_380509_1 Family membership - - - 3.699e-204 676.0
HKD1_k127_380509_10 Domain of unknown function (DUF1287) K09974 - - 0.0000000000000000000000000000000000000000000000000000000000000001267 227.0
HKD1_k127_380509_11 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000001284 224.0
HKD1_k127_380509_12 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000002112 213.0
HKD1_k127_380509_13 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000001853 200.0
HKD1_k127_380509_14 Putative TM nitroreductase - - - 0.000000000000000000000000000000007491 133.0
HKD1_k127_380509_15 - - - - 0.00000000000000000000000000000001607 130.0
HKD1_k127_380509_17 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000002023 65.0
HKD1_k127_380509_18 nucleoside 2-deoxyribosyltransferase - - - 0.00000005568 64.0
HKD1_k127_380509_2 Psort location CytoplasmicMembrane, score K07793 - - 6.12e-197 625.0
HKD1_k127_380509_3 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 410.0
HKD1_k127_380509_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 374.0
HKD1_k127_380509_5 FIST C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 319.0
HKD1_k127_380509_6 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 316.0
HKD1_k127_380509_7 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007978 269.0
HKD1_k127_380509_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000001851 252.0
HKD1_k127_380509_9 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000003678 242.0
HKD1_k127_380555_0 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 366.0
HKD1_k127_380555_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 326.0
HKD1_k127_380555_2 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 327.0
HKD1_k127_380555_3 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000001067 174.0
HKD1_k127_3872170_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.8e-254 794.0
HKD1_k127_3872170_1 Family membership - - - 1.586e-200 659.0
HKD1_k127_3872170_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000002986 147.0
HKD1_k127_3874589_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789,K18138 - - 2.201e-308 958.0
HKD1_k127_3874589_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 398.0
HKD1_k127_3874589_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000002156 269.0
HKD1_k127_3874589_3 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000008603 221.0
HKD1_k127_3874589_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000001238 136.0
HKD1_k127_3874589_5 methyltransferase - - - 0.0000000000000000000004308 104.0
HKD1_k127_3874589_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000001098 82.0
HKD1_k127_39677_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 554.0
HKD1_k127_39677_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 462.0
HKD1_k127_39677_10 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 325.0
HKD1_k127_39677_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
HKD1_k127_39677_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000002711 134.0
HKD1_k127_39677_13 S23 ribosomal protein - - - 0.000000000000000000000001542 107.0
HKD1_k127_39677_2 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 456.0
HKD1_k127_39677_3 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 452.0
HKD1_k127_39677_4 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 426.0
HKD1_k127_39677_5 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 414.0
HKD1_k127_39677_6 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 368.0
HKD1_k127_39677_7 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 366.0
HKD1_k127_39677_8 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 346.0
HKD1_k127_39677_9 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 336.0
HKD1_k127_4000_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 595.0
HKD1_k127_4000_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 522.0
HKD1_k127_4000_10 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000002383 245.0
HKD1_k127_4000_11 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
HKD1_k127_4000_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000004529 208.0
HKD1_k127_4000_13 nicotinamidase activity - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009117,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000002689 201.0
HKD1_k127_4000_14 Major Facilitator Superfamily K03535 - - 0.00000000000000000000000000000000000000000000000003418 190.0
HKD1_k127_4000_15 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000002332 151.0
HKD1_k127_4000_16 GYD domain - - - 0.0000000000000000000000000002156 117.0
HKD1_k127_4000_17 - - - - 0.0000000001466 67.0
HKD1_k127_4000_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 514.0
HKD1_k127_4000_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 500.0
HKD1_k127_4000_4 succinyl-diaminopimelate desuccinylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 448.0
HKD1_k127_4000_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 407.0
HKD1_k127_4000_6 Belongs to the D-glutamate cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 367.0
HKD1_k127_4000_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 286.0
HKD1_k127_4000_8 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002493 281.0
HKD1_k127_4000_9 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000002477 267.0
HKD1_k127_4020068_0 Aconitase C-terminal domain K01681 - 4.2.1.3 5.369e-278 868.0
HKD1_k127_4020068_1 Fumarase C C-terminus K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 562.0
HKD1_k127_4020068_2 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 539.0
HKD1_k127_4020068_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 455.0
HKD1_k127_4020068_4 PFAM AAA ATPase central domain protein K06027 - 3.6.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 385.0
HKD1_k127_4020068_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 339.0
HKD1_k127_4020068_6 PFAM transport-associated - - - 0.000000000000000000000000000000000000000000000001646 184.0
HKD1_k127_4030130_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K07469 - 1.2.99.7 0.0 1240.0
HKD1_k127_4030130_1 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 578.0
HKD1_k127_4030130_2 COG1233 Phytoene dehydrogenase and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 574.0
HKD1_k127_4030130_3 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 502.0
HKD1_k127_4030130_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 338.0
HKD1_k127_4030130_5 Protein of unknown function DUF89 K09680 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000001886 245.0
HKD1_k127_4030130_6 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002855 243.0
HKD1_k127_4030130_7 LysR substrate binding domain K21711 - - 0.0000000000000000000000000000000000000000000000000000000006302 213.0
HKD1_k127_4054350_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.368e-207 654.0
HKD1_k127_4054350_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 459.0
HKD1_k127_4054350_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003583 267.0
HKD1_k127_4054350_11 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002037 250.0
HKD1_k127_4054350_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000002264 227.0
HKD1_k127_4054350_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001897 216.0
HKD1_k127_4054350_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000005255 209.0
HKD1_k127_4054350_15 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001277 211.0
HKD1_k127_4054350_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001065 199.0
HKD1_k127_4054350_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000006833 183.0
HKD1_k127_4054350_18 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001131 178.0
HKD1_k127_4054350_19 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000888 169.0
HKD1_k127_4054350_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 419.0
HKD1_k127_4054350_20 Penicillin-binding protein, beta-lactamase class C - - - 0.00000000000000000000000000000000000000000007063 180.0
HKD1_k127_4054350_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001211 163.0
HKD1_k127_4054350_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000003603 156.0
HKD1_k127_4054350_23 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000003298 152.0
HKD1_k127_4054350_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000002165 152.0
HKD1_k127_4054350_25 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000001245 151.0
HKD1_k127_4054350_26 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002809 145.0
HKD1_k127_4054350_27 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000309 150.0
HKD1_k127_4054350_28 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000004043 136.0
HKD1_k127_4054350_29 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000001223 133.0
HKD1_k127_4054350_3 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 353.0
HKD1_k127_4054350_30 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000005473 121.0
HKD1_k127_4054350_31 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000007287 118.0
HKD1_k127_4054350_32 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001855 104.0
HKD1_k127_4054350_33 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000002603 78.0
HKD1_k127_4054350_34 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000006958 71.0
HKD1_k127_4054350_35 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001176 73.0
HKD1_k127_4054350_36 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000009955 68.0
HKD1_k127_4054350_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 329.0
HKD1_k127_4054350_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 312.0
HKD1_k127_4054350_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 319.0
HKD1_k127_4054350_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 297.0
HKD1_k127_4054350_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 289.0
HKD1_k127_4054350_9 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001868 278.0
HKD1_k127_4054871_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 8.965e-238 746.0
HKD1_k127_4054871_1 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 6.413e-216 688.0
HKD1_k127_4054871_10 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000001884 143.0
HKD1_k127_4054871_11 phosphorelay signal transduction system - - - 0.00000000000000000000000001502 118.0
HKD1_k127_4054871_12 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000003588 85.0
HKD1_k127_4054871_13 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000001533 76.0
HKD1_k127_4054871_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0005221 45.0
HKD1_k127_4054871_2 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.268e-202 643.0
HKD1_k127_4054871_3 PFAM formate nitrite transporter K06212,K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 606.0
HKD1_k127_4054871_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 543.0
HKD1_k127_4054871_5 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 354.0
HKD1_k127_4054871_6 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
HKD1_k127_4054871_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000006967 209.0
HKD1_k127_4054871_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001622 202.0
HKD1_k127_4054871_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000003903 174.0
HKD1_k127_4072210_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 566.0
HKD1_k127_4072210_1 AraC-like ligand binding domain - - - 0.000000000000000000000000008912 113.0
HKD1_k127_4072210_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000004149 85.0
HKD1_k127_4072210_3 PEP-CTERM motif - - - 0.000002147 57.0
HKD1_k127_4072210_4 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.000002597 53.0
HKD1_k127_4090527_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 9.174e-220 695.0
HKD1_k127_4090527_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 528.0
HKD1_k127_4090527_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000004357 226.0
HKD1_k127_4090527_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000002603 202.0
HKD1_k127_4090527_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000001749 188.0
HKD1_k127_4090527_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003485 177.0
HKD1_k127_4090527_14 Could be involved in septation K06412 - - 0.000000000000000000000000000000000002944 138.0
HKD1_k127_4090527_15 Orotidine 5''-phosphate decarboxylase K01591,K13421 - 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000002597 140.0
HKD1_k127_4090527_16 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000002085 124.0
HKD1_k127_4090527_17 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000001849 115.0
HKD1_k127_4090527_18 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000009198 112.0
HKD1_k127_4090527_19 Conserved carboxylase domain K01960 - 6.4.1.1 0.0000000001614 62.0
HKD1_k127_4090527_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 443.0
HKD1_k127_4090527_22 chaperone-mediated protein folding K08309,K19804 - - 0.000005096 55.0
HKD1_k127_4090527_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 421.0
HKD1_k127_4090527_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 406.0
HKD1_k127_4090527_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 379.0
HKD1_k127_4090527_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 367.0
HKD1_k127_4090527_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
HKD1_k127_4090527_8 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 349.0
HKD1_k127_4090527_9 DisA bacterial checkpoint controller nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004484 242.0
HKD1_k127_4104045_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 590.0
HKD1_k127_4104045_1 PFAM isocitrate isopropylmalate dehydrogenase K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 547.0
HKD1_k127_4104045_2 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 433.0
HKD1_k127_4104045_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 400.0
HKD1_k127_4104045_4 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.000000000000000000000000000000001397 130.0
HKD1_k127_4121777_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1190.0
HKD1_k127_4121777_1 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 565.0
HKD1_k127_4121777_10 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001049 247.0
HKD1_k127_4121777_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000000000000003567 155.0
HKD1_k127_4121777_12 PFAM Na H antiporter MnhB subunit-related protein K05566 - - 0.000000000000000000000000000000000000000512 153.0
HKD1_k127_4121777_13 PFAM cation antiporter K05569 - - 0.000000000000000000000000000000000001114 144.0
HKD1_k127_4121777_14 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.0000000000000000000000000000000001689 137.0
HKD1_k127_4121777_15 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000009139 130.0
HKD1_k127_4121777_16 Domain of unknown function (DUF4040) - - - 0.00000000000000000000000000000008519 126.0
HKD1_k127_4121777_17 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.0000000000000000000000000000001252 126.0
HKD1_k127_4121777_18 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000000000001286 94.0
HKD1_k127_4121777_19 - - - - 0.0000004342 53.0
HKD1_k127_4121777_2 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 505.0
HKD1_k127_4121777_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 497.0
HKD1_k127_4121777_4 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 464.0
HKD1_k127_4121777_5 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 454.0
HKD1_k127_4121777_6 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 318.0
HKD1_k127_4121777_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 322.0
HKD1_k127_4121777_8 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001 285.0
HKD1_k127_4121777_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000007068 267.0
HKD1_k127_4121839_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 1.167e-287 908.0
HKD1_k127_4121839_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.895e-259 816.0
HKD1_k127_4121839_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000004612 219.0
HKD1_k127_4121839_11 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
HKD1_k127_4121839_12 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000002 198.0
HKD1_k127_4121839_13 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000007559 194.0
HKD1_k127_4121839_14 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000003665 185.0
HKD1_k127_4121839_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000004675 156.0
HKD1_k127_4121839_16 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001494 132.0
HKD1_k127_4121839_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000006359 125.0
HKD1_k127_4121839_18 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000002679 109.0
HKD1_k127_4121839_19 DNA integration - - - 0.0000000000000000000001081 101.0
HKD1_k127_4121839_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.07e-253 807.0
HKD1_k127_4121839_20 von Willebrand factor (vWF) type A domain - - - 0.00000000000007336 85.0
HKD1_k127_4121839_22 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.0000000003885 65.0
HKD1_k127_4121839_23 formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.000000005576 63.0
HKD1_k127_4121839_24 - - - - 0.0000001141 58.0
HKD1_k127_4121839_28 Domain of unknown function (DUF4124) - - - 0.0006717 49.0
HKD1_k127_4121839_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 481.0
HKD1_k127_4121839_4 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 455.0
HKD1_k127_4121839_5 tyrosine recombinase K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 325.0
HKD1_k127_4121839_6 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002483 286.0
HKD1_k127_4121839_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
HKD1_k127_4121839_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000002779 252.0
HKD1_k127_4121839_9 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000001564 222.0
HKD1_k127_4199685_0 domain, Protein K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 552.0
HKD1_k127_4199685_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 301.0
HKD1_k127_4199685_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000001331 244.0
HKD1_k127_4199685_3 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000555 251.0
HKD1_k127_4199685_4 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000009617 228.0
HKD1_k127_4199685_5 Domain of unknown function (DUF4392) - - - 0.0000000000000000000000000000000000000001927 164.0
HKD1_k127_4199837_0 extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 359.0
HKD1_k127_4199837_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
HKD1_k127_4199837_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000006947 210.0
HKD1_k127_4199837_4 Membrane - - - 0.00000000000000000000008663 104.0
HKD1_k127_4199837_5 Diguanylate cyclase - - - 0.000000000000000000001319 98.0
HKD1_k127_4287104_0 DNA polymerase K02347 - - 6.96e-222 701.0
HKD1_k127_4287104_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 583.0
HKD1_k127_4287104_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 377.0
HKD1_k127_4287104_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000673 233.0
HKD1_k127_4287104_4 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000001265 51.0
HKD1_k127_4334675_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 316.0
HKD1_k127_4334675_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000007255 251.0
HKD1_k127_4336183_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 357.0
HKD1_k127_4336183_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006908 263.0
HKD1_k127_4336183_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000002732 222.0
HKD1_k127_4336183_3 NosL - - - 0.0000000000000000000000000000000000000000000000000006092 189.0
HKD1_k127_4336183_4 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000000000000000000000894 174.0
HKD1_k127_4336183_5 PFAM NosL family protein - - - 0.0000000000000000000000000000000002103 138.0
HKD1_k127_4336183_6 NADPH-dependent FMN reductase - - - 0.00000003057 58.0
HKD1_k127_4357703_0 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 463.0
HKD1_k127_4357703_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 359.0
HKD1_k127_4357703_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000007015 274.0
HKD1_k127_4357703_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000895 209.0
HKD1_k127_4357703_4 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000308 106.0
HKD1_k127_4357703_5 Alternative locus ID K09835 - 5.2.1.13 0.0000000004558 72.0
HKD1_k127_4357703_6 Addiction module antidote protein - - - 0.00009176 48.0
HKD1_k127_4367430_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008431 242.0
HKD1_k127_4367430_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005122 230.0
HKD1_k127_4367430_2 - - - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
HKD1_k127_4367430_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000008593 180.0
HKD1_k127_4367430_4 4Fe-4S dicluster domain - - - 0.0000000000000000000003197 97.0
HKD1_k127_4367430_5 Transcriptional regulator, AbrB family - - - 0.000695 46.0
HKD1_k127_4385598_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 9.64e-227 711.0
HKD1_k127_4385598_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 496.0
HKD1_k127_4385598_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 400.0
HKD1_k127_4385598_3 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 305.0
HKD1_k127_4385598_4 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000505 207.0
HKD1_k127_4385598_5 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000003688 117.0
HKD1_k127_4385598_6 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000001558 104.0
HKD1_k127_4385598_7 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000002709 57.0
HKD1_k127_4385598_8 Protein of unknown function (DUF1059) - - - 0.000004904 51.0
HKD1_k127_4396444_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
HKD1_k127_4396444_1 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004584 267.0
HKD1_k127_4396444_10 amine dehydrogenase activity - - - 0.0006086 52.0
HKD1_k127_4396444_2 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003528 256.0
HKD1_k127_4396444_3 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000003915 231.0
HKD1_k127_4396444_4 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000004077 237.0
HKD1_k127_4396444_5 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000001231 230.0
HKD1_k127_4396444_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000001737 143.0
HKD1_k127_4396444_7 Zn-dependent hydrolases including glyoxylases-like protein - - - 0.00000000000000000000000000001196 129.0
HKD1_k127_4396444_9 regulatory protein GntR HTH - - - 0.0000000000000000000000000001681 123.0
HKD1_k127_4428687_0 Enoyl-CoA hydratase/isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 9.99e-216 673.0
HKD1_k127_4428687_1 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 587.0
HKD1_k127_4428687_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 376.0
HKD1_k127_4428687_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 349.0
HKD1_k127_4428687_4 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000003039 270.0
HKD1_k127_4428687_5 Enoyl-(Acyl carrier protein) reductase K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
HKD1_k127_4428687_6 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000001481 143.0
HKD1_k127_4428687_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000233 79.0
HKD1_k127_4449804_0 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 542.0
HKD1_k127_4449804_1 Pfam:N_methyl_2 - - - 0.0000000000001577 80.0
HKD1_k127_4449804_2 type IV pilus modification protein PilV K02458,K02671 - - 0.0000000002001 66.0
HKD1_k127_4449804_3 PilX N-terminal - - - 0.000004447 55.0
HKD1_k127_4531244_0 AcrB/AcrD/AcrF family K03296 - - 3.073e-264 828.0
HKD1_k127_4531244_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.372e-247 773.0
HKD1_k127_4531244_2 Belongs to the aldehyde dehydrogenase family - - - 4.982e-206 651.0
HKD1_k127_4531244_3 hydroxyacid-oxoacid transhydrogenase activity K13954,K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.1,1.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 420.0
HKD1_k127_4531244_4 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 342.0
HKD1_k127_4531244_5 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000000000000005387 178.0
HKD1_k127_4531244_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000003381 173.0
HKD1_k127_4531244_7 - - - - 0.000000000000000001989 85.0
HKD1_k127_4531244_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0008114 50.0
HKD1_k127_4542036_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.492e-206 649.0
HKD1_k127_4542036_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 417.0
HKD1_k127_4542036_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 354.0
HKD1_k127_4542036_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 289.0
HKD1_k127_4542036_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000001224 155.0
HKD1_k127_4542036_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000002195 157.0
HKD1_k127_4542036_6 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000001406 116.0
HKD1_k127_455242_0 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000008235 161.0
HKD1_k127_455242_1 Flavodoxin K03809 - 1.6.5.2 0.00000000000000000000002722 104.0
HKD1_k127_455242_2 PFAM ATP-binding region ATPase domain protein - - - 0.0003961 46.0
HKD1_k127_4566944_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.616e-306 945.0
HKD1_k127_4566944_1 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 347.0
HKD1_k127_4566944_2 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 310.0
HKD1_k127_4566944_3 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000648 277.0
HKD1_k127_4566944_4 PFAM Alkaline phosphatase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 277.0
HKD1_k127_4566944_5 Glycerol-3-phosphate dehydrogenase K00112 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000408 241.0
HKD1_k127_4566944_6 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000001043 202.0
HKD1_k127_4566944_7 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000009226 157.0
HKD1_k127_4566944_8 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575 1.1.5.3 0.0000000001058 63.0
HKD1_k127_4627533_0 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 376.0
HKD1_k127_4627533_1 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001159 299.0
HKD1_k127_4627533_10 PilZ domain - - - 0.00006976 50.0
HKD1_k127_4627533_11 type IV pilus modification protein PilV K02458,K02671 - - 0.0004084 48.0
HKD1_k127_4627533_2 COG1082 Sugar phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000008671 244.0
HKD1_k127_4627533_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000726 170.0
HKD1_k127_4627533_4 HD domain - - - 0.0000000000000000000000000000000000000000508 163.0
HKD1_k127_4627533_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000007914 147.0
HKD1_k127_4627533_6 KduI/IolB family K03337 - 5.3.1.30 0.0000000000000000000000003881 117.0
HKD1_k127_4627533_7 Prokaryotic N-terminal methylation motif K02672 - - 0.000005085 57.0
HKD1_k127_4627533_8 PhoQ Sensor - - - 0.00001427 56.0
HKD1_k127_4627533_9 PilX N-terminal - - - 0.00004061 51.0
HKD1_k127_4682265_0 General secretory system II, protein E domain protein K02652 - - 3.675e-218 692.0
HKD1_k127_4682265_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 4.971e-216 691.0
HKD1_k127_4682265_10 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 379.0
HKD1_k127_4682265_11 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 388.0
HKD1_k127_4682265_12 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 336.0
HKD1_k127_4682265_13 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 341.0
HKD1_k127_4682265_14 ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 327.0
HKD1_k127_4682265_15 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 314.0
HKD1_k127_4682265_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 312.0
HKD1_k127_4682265_17 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 314.0
HKD1_k127_4682265_18 PFAM Glycosyl transferase family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000771 275.0
HKD1_k127_4682265_19 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000005679 269.0
HKD1_k127_4682265_2 PFAM asparagine synthase K01953 - 6.3.5.4 3.032e-194 625.0
HKD1_k127_4682265_20 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001289 259.0
HKD1_k127_4682265_21 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003018 266.0
HKD1_k127_4682265_22 PFAM ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006033 246.0
HKD1_k127_4682265_23 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000916 249.0
HKD1_k127_4682265_24 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000002669 238.0
HKD1_k127_4682265_25 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000001505 227.0
HKD1_k127_4682265_26 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000008669 194.0
HKD1_k127_4682265_27 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000001003 192.0
HKD1_k127_4682265_28 PFAM glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000000000000000000006775 193.0
HKD1_k127_4682265_29 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000155 179.0
HKD1_k127_4682265_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 618.0
HKD1_k127_4682265_30 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000003713 168.0
HKD1_k127_4682265_31 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000002842 156.0
HKD1_k127_4682265_32 Tetratricopeptide repeat - - - 0.000000000000000000000000000002032 129.0
HKD1_k127_4682265_33 protein-(glutamine-N5) methyltransferase activity K00571 - 2.1.1.72 0.00000000000000000000000000000478 132.0
HKD1_k127_4682265_34 Methyltransferase domain - - - 0.000000000000000000000001074 113.0
HKD1_k127_4682265_35 Methyltransferase FkbM domain - - - 0.0000000000000000000000251 105.0
HKD1_k127_4682265_36 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000009181 105.0
HKD1_k127_4682265_37 protein methyltransferase activity - - - 0.00000000000000001546 84.0
HKD1_k127_4682265_38 Methyltransferase domain - - - 0.00000000000000001625 93.0
HKD1_k127_4682265_39 DNA-binding transcription factor activity - - - 0.00000000000000002605 90.0
HKD1_k127_4682265_4 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 510.0
HKD1_k127_4682265_40 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000000000206 81.0
HKD1_k127_4682265_41 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000004693 77.0
HKD1_k127_4682265_42 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000002498 76.0
HKD1_k127_4682265_43 Membrane - - - 0.000000000007809 78.0
HKD1_k127_4682265_44 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000422 76.0
HKD1_k127_4682265_45 Nodulation protein S (NodS) - - - 0.00000003141 64.0
HKD1_k127_4682265_46 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000006901 59.0
HKD1_k127_4682265_47 Methionine biosynthesis protein MetW - - - 0.000009476 56.0
HKD1_k127_4682265_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 496.0
HKD1_k127_4682265_6 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 479.0
HKD1_k127_4682265_7 PFAM glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 451.0
HKD1_k127_4682265_8 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008962 401.0
HKD1_k127_4682265_9 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 386.0
HKD1_k127_4687221_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 5.365e-263 816.0
HKD1_k127_4687221_1 Cysteine-rich domain - - - 2.977e-215 674.0
HKD1_k127_4687221_10 Receptor family ligand binding region K01999 - - 0.0000000000000000000007701 96.0
HKD1_k127_4687221_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 385.0
HKD1_k127_4687221_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 384.0
HKD1_k127_4687221_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080,K14082 - 2.1.1.246,2.1.1.247,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 372.0
HKD1_k127_4687221_5 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 344.0
HKD1_k127_4687221_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 306.0
HKD1_k127_4687221_7 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000819 276.0
HKD1_k127_4687221_8 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001716 245.0
HKD1_k127_4687221_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.00000000000000000000000000000000000000000000000000000000000002735 222.0
HKD1_k127_4745783_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1228.0
HKD1_k127_4745783_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 592.0
HKD1_k127_4745783_2 membrane - - - 0.000000000000000000000000000004446 122.0
HKD1_k127_4745783_3 Sporulation and spore germination - - - 0.0000000000000000000000000002474 122.0
HKD1_k127_4745783_4 Endonuclease containing a URI domain K07461 - - 0.000000000000002502 78.0
HKD1_k127_4745783_5 Endonuclease containing a URI domain K07461 - - 0.00000000004256 66.0
HKD1_k127_4818337_0 Elongation factor Tu domain 2 K02355 - - 2.155e-265 834.0
HKD1_k127_4818337_1 Domain of unknown function (DUF362) K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 443.0
HKD1_k127_4818337_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 329.0
HKD1_k127_4818337_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000912 249.0
HKD1_k127_4818337_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000318 134.0
HKD1_k127_4818337_5 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000001866 52.0
HKD1_k127_48550_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.556e-208 659.0
HKD1_k127_48550_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 534.0
HKD1_k127_48550_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 496.0
HKD1_k127_48550_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000001504 117.0
HKD1_k127_48550_4 Ion channel - - - 0.000000000000162 71.0
HKD1_k127_4972287_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 372.0
HKD1_k127_4972287_1 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 339.0
HKD1_k127_4972287_2 Biotin-protein ligase, N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 343.0
HKD1_k127_4972287_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005212 241.0
HKD1_k127_4972287_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000004686 167.0
HKD1_k127_5034415_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.601e-277 864.0
HKD1_k127_5034415_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 438.0
HKD1_k127_5034415_2 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 380.0
HKD1_k127_5034415_3 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 357.0
HKD1_k127_5034415_4 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006194 275.0
HKD1_k127_5034415_5 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000002665 217.0
HKD1_k127_5034415_6 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000001007 159.0
HKD1_k127_5034415_7 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000009999 147.0
HKD1_k127_5034415_8 Ribbon-helix-helix protein, copG family - - - 0.00000000000000001369 85.0
HKD1_k127_5034415_9 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.0000000000001384 77.0
HKD1_k127_5036754_0 Aldehyde dehydrogenase family K22187 - - 1.246e-200 636.0
HKD1_k127_5036754_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 424.0
HKD1_k127_5036754_2 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 398.0
HKD1_k127_5036754_3 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000103 156.0
HKD1_k127_5036754_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000000008739 133.0
HKD1_k127_5036754_5 Cell Wall K01448 - 3.5.1.28 0.0000002636 62.0
HKD1_k127_5036754_6 PFAM response regulator receiver K07658,K07668 - - 0.0008562 43.0
HKD1_k127_5045430_0 PFAM Type II secretion system protein E K02283,K03609 - - 7.861e-196 621.0
HKD1_k127_5045430_1 Type II and III secretion system protein K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 492.0
HKD1_k127_5045430_10 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000001345 181.0
HKD1_k127_5045430_11 PFAM TadE family protein - - - 0.0000000000000000000000000000007552 126.0
HKD1_k127_5045430_12 COG3209 Rhs family protein - - - 0.0000000000000000000000000335 126.0
HKD1_k127_5045430_13 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000002621 107.0
HKD1_k127_5045430_14 domain, Protein K20276 - - 0.0000000000000000001378 105.0
HKD1_k127_5045430_15 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000002219 76.0
HKD1_k127_5045430_16 - - - - 0.0000000000001293 75.0
HKD1_k127_5045430_17 Flp/Fap pilin component K02651 - - 0.0000003704 53.0
HKD1_k127_5045430_2 PFAM TadE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 479.0
HKD1_k127_5045430_3 transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 444.0
HKD1_k127_5045430_4 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 405.0
HKD1_k127_5045430_5 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 367.0
HKD1_k127_5045430_6 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 297.0
HKD1_k127_5045430_7 PFAM type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004594 286.0
HKD1_k127_5045430_8 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000493 282.0
HKD1_k127_5045430_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000007117 244.0
HKD1_k127_5050209_0 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000009411 252.0
HKD1_k127_5050209_1 DoxX K15977 - - 0.00000000000000000000000000001045 123.0
HKD1_k127_5050209_2 cell redox homeostasis - - - 0.000000000000000005563 83.0
HKD1_k127_5050209_3 response to heat - - - 0.000000653 53.0
HKD1_k127_5063090_0 B-1 B cell differentiation - - - 0.0 1094.0
HKD1_k127_5063090_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.041e-242 759.0
HKD1_k127_5063090_2 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 5.101e-197 622.0
HKD1_k127_5063090_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 463.0
HKD1_k127_5063090_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 378.0
HKD1_k127_5063090_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 382.0
HKD1_k127_5063090_6 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000001253 154.0
HKD1_k127_5063090_7 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000003157 136.0
HKD1_k127_5063090_8 NADPH-dependent FMN reductase - - - 0.00000000000000000000004491 106.0
HKD1_k127_5063090_9 - - - - 0.00000000328 64.0
HKD1_k127_5078591_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.998e-233 735.0
HKD1_k127_5078591_1 Tripartite tricarboxylate transporter TctA family - - - 2.699e-218 687.0
HKD1_k127_5078591_10 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000001284 231.0
HKD1_k127_5078591_11 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000003173 220.0
HKD1_k127_5078591_12 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000002133 218.0
HKD1_k127_5078591_13 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000003041 194.0
HKD1_k127_5078591_14 Nitroreductase family - - - 0.0000000000000000000000000000000000000000002188 166.0
HKD1_k127_5078591_15 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000005607 134.0
HKD1_k127_5078591_16 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000742 106.0
HKD1_k127_5078591_17 amidohydrolase K01845 - 5.4.3.8 0.00000000000000000000001036 113.0
HKD1_k127_5078591_18 Cysteine-rich domain - - - 0.000000000000001997 78.0
HKD1_k127_5078591_19 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.000000001446 70.0
HKD1_k127_5078591_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 483.0
HKD1_k127_5078591_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 490.0
HKD1_k127_5078591_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 404.0
HKD1_k127_5078591_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 297.0
HKD1_k127_5078591_6 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004531 288.0
HKD1_k127_5078591_7 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006543 282.0
HKD1_k127_5078591_8 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000002368 249.0
HKD1_k127_5078591_9 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000001021 249.0
HKD1_k127_5109223_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000001971 187.0
HKD1_k127_5109223_1 FCD - - - 0.000000001796 62.0
HKD1_k127_5117343_0 denitrification pathway - - - 4.371e-225 715.0
HKD1_k127_5117343_1 Cytochrome c554 and c-prime - - - 0.000000000000000000361 95.0
HKD1_k127_5117343_2 Regulatory protein, FmdB - - - 0.00006021 50.0
HKD1_k127_5121791_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.753e-260 813.0
HKD1_k127_5121791_1 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
HKD1_k127_5121791_10 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000004053 175.0
HKD1_k127_5121791_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000002012 166.0
HKD1_k127_5121791_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000008348 124.0
HKD1_k127_5121791_13 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000001606 120.0
HKD1_k127_5121791_14 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.0000000000000000000000294 104.0
HKD1_k127_5121791_15 - - - - 0.000000000000000000002347 100.0
HKD1_k127_5121791_2 NnrS protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 360.0
HKD1_k127_5121791_3 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 342.0
HKD1_k127_5121791_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009434 252.0
HKD1_k127_5121791_5 Flavodoxin domain K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000008956 242.0
HKD1_k127_5121791_6 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000003211 212.0
HKD1_k127_5121791_7 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000003199 214.0
HKD1_k127_5121791_8 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000006346 200.0
HKD1_k127_5121791_9 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000001534 196.0
HKD1_k127_5122445_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009328 239.0
HKD1_k127_5122445_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000006647 211.0
HKD1_k127_5122445_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000003296 203.0
HKD1_k127_5131496_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 347.0
HKD1_k127_5131496_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 322.0
HKD1_k127_5131496_2 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000001834 163.0
HKD1_k127_5131496_3 Putative beta-barrel porin 2 - - - 0.000000000000001468 89.0
HKD1_k127_5131496_4 GGDEF domain K19707 - - 0.00000000808 63.0
HKD1_k127_5131496_5 response regulator K07315 - 3.1.3.3 0.0001576 49.0
HKD1_k127_5133012_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 5.776e-321 989.0
HKD1_k127_5133012_1 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 360.0
HKD1_k127_5133012_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 336.0
HKD1_k127_5133012_3 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00000000000000000000000000004603 120.0
HKD1_k127_5137919_0 Psort location Cytoplasmic, score - - - 0.0 1590.0
HKD1_k127_5137919_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0 1020.0
HKD1_k127_5137919_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
HKD1_k127_5137919_11 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 306.0
HKD1_k127_5137919_12 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004644 274.0
HKD1_k127_5137919_13 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000001825 237.0
HKD1_k127_5137919_14 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000008252 246.0
HKD1_k127_5137919_15 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000003734 229.0
HKD1_k127_5137919_16 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000005144 220.0
HKD1_k127_5137919_17 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000008301 218.0
HKD1_k127_5137919_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000105 203.0
HKD1_k127_5137919_19 Glycine cleavage system H protein K02437 - - 0.00000000000000000000000000000000000000000000007438 172.0
HKD1_k127_5137919_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 1.307e-236 741.0
HKD1_k127_5137919_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000009306 175.0
HKD1_k127_5137919_21 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000007161 171.0
HKD1_k127_5137919_22 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000000002806 117.0
HKD1_k127_5137919_23 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000005902 115.0
HKD1_k127_5137919_24 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000003088 83.0
HKD1_k127_5137919_25 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000002109 74.0
HKD1_k127_5137919_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0002416 44.0
HKD1_k127_5137919_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 574.0
HKD1_k127_5137919_4 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 558.0
HKD1_k127_5137919_5 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 447.0
HKD1_k127_5137919_6 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 402.0
HKD1_k127_5137919_7 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 320.0
HKD1_k127_5137919_8 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 317.0
HKD1_k127_5137919_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 319.0
HKD1_k127_5155141_0 cog cog2801 K07497 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000005135 99.0
HKD1_k127_5158766_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 407.0
HKD1_k127_5158766_1 peptidyl-tyrosine sulfation - - - 0.0002437 51.0
HKD1_k127_5175609_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 8.944e-228 716.0
HKD1_k127_5175609_1 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 3.318e-227 715.0
HKD1_k127_5175609_10 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 286.0
HKD1_k127_5175609_11 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000007301 209.0
HKD1_k127_5175609_12 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000006727 207.0
HKD1_k127_5175609_13 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000077 194.0
HKD1_k127_5175609_14 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.0000000000000000000000000000002629 123.0
HKD1_k127_5175609_15 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000004063 94.0
HKD1_k127_5175609_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.008e-226 718.0
HKD1_k127_5175609_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.688e-206 666.0
HKD1_k127_5175609_4 acyl-coa dehydrogenase - - - 3.079e-194 611.0
HKD1_k127_5175609_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 621.0
HKD1_k127_5175609_6 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 539.0
HKD1_k127_5175609_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 495.0
HKD1_k127_5175609_8 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 379.0
HKD1_k127_5175609_9 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
HKD1_k127_5176064_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 615.0
HKD1_k127_5176064_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 604.0
HKD1_k127_5176064_10 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 359.0
HKD1_k127_5176064_11 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 344.0
HKD1_k127_5176064_12 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
HKD1_k127_5176064_13 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 332.0
HKD1_k127_5176064_14 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 317.0
HKD1_k127_5176064_15 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 313.0
HKD1_k127_5176064_16 transport system periplasmic component K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 314.0
HKD1_k127_5176064_17 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 313.0
HKD1_k127_5176064_18 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004119 259.0
HKD1_k127_5176064_19 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000004976 240.0
HKD1_k127_5176064_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 540.0
HKD1_k127_5176064_20 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001017 206.0
HKD1_k127_5176064_21 regulatory protein GntR HTH - - - 0.00000000000000000000000000000008822 132.0
HKD1_k127_5176064_22 4 iron, 4 sulfur cluster binding K00176,K05524 - 1.2.7.3 0.00000000000000000004326 93.0
HKD1_k127_5176064_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000004025 89.0
HKD1_k127_5176064_24 Tripartite tricarboxylate transporter TctB family - - - 0.0001133 50.0
HKD1_k127_5176064_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 469.0
HKD1_k127_5176064_4 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 453.0
HKD1_k127_5176064_5 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 445.0
HKD1_k127_5176064_6 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 445.0
HKD1_k127_5176064_7 proline dipeptidase activity K18829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 410.0
HKD1_k127_5176064_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 372.0
HKD1_k127_5176064_9 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 367.0
HKD1_k127_5180936_0 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006861 258.0
HKD1_k127_5180936_1 self proteolysis - - - 0.00000000000000000000000000000000000187 150.0
HKD1_k127_5180936_2 pilus assembly protein PilW - - - 0.0000000000007126 79.0
HKD1_k127_5180936_3 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000003245 65.0
HKD1_k127_5180936_4 Prokaryotic N-terminal methylation motif K08084 - - 0.00000003136 61.0
HKD1_k127_5180936_5 PilX N-terminal - - - 0.000006202 54.0
HKD1_k127_5181236_0 PFAM Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 2.886e-255 799.0
HKD1_k127_5181236_1 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 520.0
HKD1_k127_5181236_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 330.0
HKD1_k127_5181236_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005023 256.0
HKD1_k127_5181236_4 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000001406 84.0
HKD1_k127_5181236_5 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000001424 76.0
HKD1_k127_5182540_0 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 491.0
HKD1_k127_5182540_1 carboxylase K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000006234 90.0
HKD1_k127_5182540_2 PFAM Pyruvate carboxyltransferase - - - 0.000000004514 57.0
HKD1_k127_5200695_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 6.252e-290 907.0
HKD1_k127_5200695_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.547e-271 850.0
HKD1_k127_5200695_2 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 586.0
HKD1_k127_5200695_3 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 580.0
HKD1_k127_5200695_4 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 507.0
HKD1_k127_5200695_5 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 501.0
HKD1_k127_5200695_6 Mechanosensitive ion channel - - - 0.000000000000000000000000006208 125.0
HKD1_k127_5200695_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000007233 100.0
HKD1_k127_5200695_8 PEP-CTERM motif - - - 0.00001574 54.0
HKD1_k127_5200695_9 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 GO:0003674,GO:0003824,GO:0004805,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009507,GO:0009536,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0022603,GO:0030312,GO:0034637,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0048831,GO:0050789,GO:0050793,GO:0051239,GO:0060688,GO:0065007,GO:0071704,GO:0071944,GO:1900618,GO:1901576,GO:1905428,GO:2000026,GO:2000032 3.1.3.12 0.0000229 48.0
HKD1_k127_5210431_0 Domain of unknown function (DUF3842) - - - 0.00000000000000000000000000000000000000000001008 166.0
HKD1_k127_5210431_1 5'-nucleotidase, C-terminal domain K01081,K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000003216 139.0
HKD1_k127_5210431_2 - - - - 0.0000000000006978 73.0
HKD1_k127_5221622_0 Ammonium Transporter Family K03320 - - 4.375e-209 657.0
HKD1_k127_5221622_1 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 336.0
HKD1_k127_5221622_2 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000007137 219.0
HKD1_k127_5221622_3 - - - - 0.00000000000000000000000000000000000000000000000000000003056 207.0
HKD1_k127_5221622_4 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000002135 201.0
HKD1_k127_5221622_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000001327 187.0
HKD1_k127_5221622_6 Domain of unknown function (DUF362) - - - 0.000000000000000000000009985 104.0
HKD1_k127_5223443_0 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 459.0
HKD1_k127_5223443_1 extracellular ligand-binding receptor K01999 - - 0.000000000000003308 80.0
HKD1_k127_5230036_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 5.266e-312 987.0
HKD1_k127_5230036_1 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 9.162e-282 897.0
HKD1_k127_5230036_10 binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 368.0
HKD1_k127_5230036_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 336.0
HKD1_k127_5230036_12 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 354.0
HKD1_k127_5230036_13 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 327.0
HKD1_k127_5230036_14 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005309 256.0
HKD1_k127_5230036_15 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000001228 238.0
HKD1_k127_5230036_16 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000001405 223.0
HKD1_k127_5230036_17 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000002713 201.0
HKD1_k127_5230036_18 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000001344 165.0
HKD1_k127_5230036_19 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000001366 162.0
HKD1_k127_5230036_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 520.0
HKD1_k127_5230036_20 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000000000005504 160.0
HKD1_k127_5230036_21 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000008743 133.0
HKD1_k127_5230036_22 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000000000000000002275 134.0
HKD1_k127_5230036_23 Dodecin K09165 - - 0.00000000000000000000007774 99.0
HKD1_k127_5230036_24 Pfam Response regulator receiver - - - 0.0000000000000000000006079 100.0
HKD1_k127_5230036_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 493.0
HKD1_k127_5230036_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 459.0
HKD1_k127_5230036_5 CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 451.0
HKD1_k127_5230036_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 430.0
HKD1_k127_5230036_7 cell adhesion involved in biofilm formation K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 394.0
HKD1_k127_5230036_8 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 387.0
HKD1_k127_5230036_9 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 374.0
HKD1_k127_52385_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1056.0
HKD1_k127_52385_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 454.0
HKD1_k127_52385_10 - - - - 0.0000002295 54.0
HKD1_k127_52385_2 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 443.0
HKD1_k127_52385_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 369.0
HKD1_k127_52385_4 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000005015 264.0
HKD1_k127_52385_5 Jag_N K06346 - - 0.00000000000000000000000000000006436 130.0
HKD1_k127_52385_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000007789 98.0
HKD1_k127_52385_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000001122 78.0
HKD1_k127_52385_8 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000201 70.0
HKD1_k127_52385_9 Domain of unknown function (DUF362) - - - 0.00000000001145 68.0
HKD1_k127_5245420_0 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 1.342e-229 713.0
HKD1_k127_5245420_1 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 503.0
HKD1_k127_5245420_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 378.0
HKD1_k127_5245420_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 337.0
HKD1_k127_5245420_4 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 307.0
HKD1_k127_5245420_5 Belongs to the arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
HKD1_k127_5245420_6 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000001281 217.0
HKD1_k127_5245420_7 PFAM Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000001181 187.0
HKD1_k127_5245420_8 Protein of unknown function (DUF1571) - - - 0.00000000000000000000000000000000002625 144.0
HKD1_k127_5277263_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 396.0
HKD1_k127_5277263_1 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
HKD1_k127_5277263_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001175 240.0
HKD1_k127_5277263_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
HKD1_k127_5277263_5 dihydromethanopterin reductase activity - - - 0.00000000000000000000000000000000000002581 146.0
HKD1_k127_5277263_6 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000001384 108.0
HKD1_k127_5277263_7 - - - - 0.0000000000000000000000001469 107.0
HKD1_k127_5277263_8 Domain of unknown function (DUF4115) K15539 - - 0.00000004711 61.0
HKD1_k127_5277263_9 Protein of unknown function (DUF2914) - - - 0.0006183 48.0
HKD1_k127_5280435_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 469.0
HKD1_k127_5280435_1 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 440.0
HKD1_k127_5280435_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 426.0
HKD1_k127_5280435_3 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 389.0
HKD1_k127_5280435_4 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
HKD1_k127_5280435_5 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000002063 172.0
HKD1_k127_5280435_6 Transcription regulator MerR DNA binding K21902 - - 0.0000000000000000000000000000000000001453 146.0
HKD1_k127_5280435_7 DRTGG domain protein - - - 0.000000000000000000000000001194 115.0
HKD1_k127_5280459_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 596.0
HKD1_k127_5280459_1 dioxygenase K15777 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 332.0
HKD1_k127_5280459_10 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000003944 151.0
HKD1_k127_5280459_12 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000000000000000001887 121.0
HKD1_k127_5280459_13 Alkylmercury lyase - - - 0.00000000000000000000000000005966 116.0
HKD1_k127_5280459_14 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000001617 107.0
HKD1_k127_5280459_15 - - - - 0.000000000008565 72.0
HKD1_k127_5280459_16 - - - - 0.0000002911 56.0
HKD1_k127_5280459_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 335.0
HKD1_k127_5280459_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 256.0
HKD1_k127_5280459_4 PFAM metal-dependent phosphohydrolase HD sub - - - 0.000000000000000000000000000000000000000000000000000000000000000000001226 244.0
HKD1_k127_5280459_5 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000001384 220.0
HKD1_k127_5280459_6 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000006032 211.0
HKD1_k127_5280459_7 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000002402 180.0
HKD1_k127_5280459_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000003434 164.0
HKD1_k127_5280459_9 Alkylmercury lyase - - - 0.000000000000000000000000000000000000000006782 155.0
HKD1_k127_5284159_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 501.0
HKD1_k127_5284159_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 369.0
HKD1_k127_5284159_2 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000002402 138.0
HKD1_k127_5299894_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 501.0
HKD1_k127_5299894_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 476.0
HKD1_k127_5299894_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000001829 210.0
HKD1_k127_5299894_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000000000001156 183.0
HKD1_k127_5299894_12 ACT domain - - - 0.000000000000000000000000000000000000000000000001766 177.0
HKD1_k127_5299894_13 Male sterility protein - - - 0.00000000000000000000000000000000000000000000005889 181.0
HKD1_k127_5299894_14 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000002965 146.0
HKD1_k127_5299894_15 protein trimerization - - - 0.000000000000000000001704 110.0
HKD1_k127_5299894_16 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000003958 89.0
HKD1_k127_5299894_17 Putative regulatory protein - - - 0.0000000000103 69.0
HKD1_k127_5299894_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 463.0
HKD1_k127_5299894_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 458.0
HKD1_k127_5299894_4 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 447.0
HKD1_k127_5299894_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 413.0
HKD1_k127_5299894_6 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 429.0
HKD1_k127_5299894_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 387.0
HKD1_k127_5299894_8 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 355.0
HKD1_k127_5299894_9 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006433 263.0
HKD1_k127_5323587_0 (ABC) transporter K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 517.0
HKD1_k127_5323587_1 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000003714 188.0
HKD1_k127_5323587_2 SMART Cold shock protein K03704 - - 0.000000000000000000000005053 102.0
HKD1_k127_5323587_3 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.0000000000002841 74.0
HKD1_k127_5323587_4 HEAT repeats - - - 0.00003492 57.0
HKD1_k127_5329450_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002195 241.0
HKD1_k127_5329450_1 cheY-homologous receiver domain - - - 0.0000000000005092 75.0
HKD1_k127_5358919_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.455e-236 745.0
HKD1_k127_5358919_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 3.026e-214 674.0
HKD1_k127_5358919_10 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000002568 231.0
HKD1_k127_5358919_11 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000003706 209.0
HKD1_k127_5358919_13 Endonuclease containing a URI domain - - - 0.000004035 51.0
HKD1_k127_5358919_14 Helix-turn-helix domain - - - 0.0001057 49.0
HKD1_k127_5358919_2 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 1.055e-199 635.0
HKD1_k127_5358919_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 514.0
HKD1_k127_5358919_4 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 435.0
HKD1_k127_5358919_5 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 413.0
HKD1_k127_5358919_6 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 393.0
HKD1_k127_5358919_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000006975 273.0
HKD1_k127_5358919_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 259.0
HKD1_k127_5358919_9 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
HKD1_k127_5374230_0 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 5.216e-206 653.0
HKD1_k127_5374230_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 443.0
HKD1_k127_5374230_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000003416 209.0
HKD1_k127_5374230_11 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000002881 203.0
HKD1_k127_5374230_13 Protein of unknown function (DUF721) - - - 0.00000000000000001204 89.0
HKD1_k127_5374230_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.00000000000001796 81.0
HKD1_k127_5374230_15 amine dehydrogenase activity - - - 0.0001228 47.0
HKD1_k127_5374230_2 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 344.0
HKD1_k127_5374230_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 293.0
HKD1_k127_5374230_4 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002665 284.0
HKD1_k127_5374230_5 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 287.0
HKD1_k127_5374230_6 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003778 261.0
HKD1_k127_5374230_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001071 257.0
HKD1_k127_5374230_8 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000008899 249.0
HKD1_k127_5374230_9 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000009146 228.0
HKD1_k127_538270_0 Protein of unknown function, DUF255 K06888 - - 3.582e-221 707.0
HKD1_k127_538270_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 406.0
HKD1_k127_538270_10 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000005557 212.0
HKD1_k127_538270_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000002149 203.0
HKD1_k127_538270_12 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
HKD1_k127_538270_13 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000004171 164.0
HKD1_k127_538270_14 Belongs to the Fur family K03711 - - 0.00000000000000000000002607 104.0
HKD1_k127_538270_15 Universal stress protein family - - - 0.0000000000000000000172 96.0
HKD1_k127_538270_16 Membrane - - - 0.0000000000000002328 89.0
HKD1_k127_538270_18 Cobalt transport protein K02008 - - 0.000006047 57.0
HKD1_k127_538270_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 338.0
HKD1_k127_538270_3 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 326.0
HKD1_k127_538270_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 310.0
HKD1_k127_538270_5 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 295.0
HKD1_k127_538270_6 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003495 288.0
HKD1_k127_538270_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009532 246.0
HKD1_k127_538270_8 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000003906 236.0
HKD1_k127_538270_9 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001993 226.0
HKD1_k127_5389478_0 dEAD DEAH box helicase K06877 - - 2.262e-277 869.0
HKD1_k127_5389478_1 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 370.0
HKD1_k127_5389478_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 333.0
HKD1_k127_5389478_3 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 339.0
HKD1_k127_5389478_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001126 157.0
HKD1_k127_5389478_5 Putative transmembrane protein (PGPGW) - - - 0.000000000000129 73.0
HKD1_k127_5389478_6 - - - - 0.00000000001501 71.0
HKD1_k127_5390288_0 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 327.0
HKD1_k127_5390288_1 Glycine sarcosine betaine reductase K10671 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000000000432 226.0
HKD1_k127_5390288_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000007812 123.0
HKD1_k127_5390288_3 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672 - 1.21.4.2 0.00000000000000004867 83.0
HKD1_k127_5392828_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1212.0
HKD1_k127_5392828_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1036.0
HKD1_k127_5392828_10 small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 372.0
HKD1_k127_5392828_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 370.0
HKD1_k127_5392828_12 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 351.0
HKD1_k127_5392828_13 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 330.0
HKD1_k127_5392828_14 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 321.0
HKD1_k127_5392828_15 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 292.0
HKD1_k127_5392828_16 TAT (twin-arginine translocation) pathway signal sequence K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009959 272.0
HKD1_k127_5392828_17 thiamine-phosphate kinase activity K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000006688 260.0
HKD1_k127_5392828_18 PFAM Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000008232 228.0
HKD1_k127_5392828_19 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000001809 219.0
HKD1_k127_5392828_2 Heat shock 70 kDa protein K04043 - - 3.553e-314 972.0
HKD1_k127_5392828_20 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000004927 219.0
HKD1_k127_5392828_21 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000002246 192.0
HKD1_k127_5392828_22 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000004989 196.0
HKD1_k127_5392828_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000001753 171.0
HKD1_k127_5392828_24 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000004555 172.0
HKD1_k127_5392828_25 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000008565 158.0
HKD1_k127_5392828_26 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000001391 155.0
HKD1_k127_5392828_27 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000008523 140.0
HKD1_k127_5392828_28 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000004114 146.0
HKD1_k127_5392828_29 AhpC/TSA family - - - 0.00000000000000000000006187 100.0
HKD1_k127_5392828_3 Belongs to the carbamoyltransferase HypF family K04656 - - 1.379e-264 834.0
HKD1_k127_5392828_30 AhpC/TSA family - - - 0.00000000000000000004086 93.0
HKD1_k127_5392828_31 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000004592 94.0
HKD1_k127_5392828_32 DUF167 K09131 - - 0.0000000000000000002331 90.0
HKD1_k127_5392828_33 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000004961 87.0
HKD1_k127_5392828_34 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000001308 85.0
HKD1_k127_5392828_4 PFAM Nickel-dependent hydrogenase, large subunit K06281 - 1.12.99.6 2.768e-203 642.0
HKD1_k127_5392828_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 601.0
HKD1_k127_5392828_6 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 546.0
HKD1_k127_5392828_7 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 496.0
HKD1_k127_5392828_8 Hydrogenase expression formation protein hypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 441.0
HKD1_k127_5392828_9 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 416.0
HKD1_k127_5422935_0 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000191 256.0
HKD1_k127_5422935_1 HIT domain K02503 - - 0.0000000000000000000000000000000000000000001569 161.0
HKD1_k127_5422935_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000004627 165.0
HKD1_k127_5422935_3 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000661 164.0
HKD1_k127_5422935_4 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000001005 145.0
HKD1_k127_5436458_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001288 271.0
HKD1_k127_5436458_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000009537 199.0
HKD1_k127_5436458_2 HEAT repeats - - - 0.000000000000000000001676 102.0
HKD1_k127_5436458_3 PHP domain protein K02347 - - 0.000009705 49.0
HKD1_k127_5436458_4 Helix-turn-helix domain - - - 0.00004286 49.0
HKD1_k127_5471136_0 COG0330 Membrane protease subunits stomatin prohibitin - - - 0.00000000000000000000000000000000000000000000000001433 190.0
HKD1_k127_5471136_1 Domain of unknown function (DUF4404) - - - 0.00000000000000000000000000000000002581 137.0
HKD1_k127_5471136_2 RNA recognition motif - - - 0.00000000000000000000000001139 113.0
HKD1_k127_5471136_3 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000168 71.0
HKD1_k127_5471136_4 Probable zinc-ribbon domain - - - 0.0003852 45.0
HKD1_k127_5499272_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 389.0
HKD1_k127_5499272_1 LamB/YcsF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008901 274.0
HKD1_k127_5499272_2 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001753 270.0
HKD1_k127_5499272_3 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004114 240.0
HKD1_k127_5499272_4 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000001061 189.0
HKD1_k127_5499272_5 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000009311 117.0
HKD1_k127_5499272_6 Alkylmercury lyase - - - 0.000000000000000000108 91.0
HKD1_k127_5499272_8 Alkylmercury lyase - - - 0.000000000405 62.0
HKD1_k127_5513249_0 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 540.0
HKD1_k127_5513249_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 404.0
HKD1_k127_5513249_10 PFAM Class III cytochrome C family - - - 0.0000000000000002453 83.0
HKD1_k127_5513249_11 virion core protein, lumpy skin disease virus - - - 0.000003595 56.0
HKD1_k127_5513249_12 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00001105 57.0
HKD1_k127_5513249_13 - K06039,K07092 - - 0.00007705 51.0
HKD1_k127_5513249_14 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0005274 48.0
HKD1_k127_5513249_2 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 394.0
HKD1_k127_5513249_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 291.0
HKD1_k127_5513249_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000171 279.0
HKD1_k127_5513249_5 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001058 281.0
HKD1_k127_5513249_6 NOG31153 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004577 251.0
HKD1_k127_5513249_7 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000001325 227.0
HKD1_k127_5513249_8 Predicted membrane protein (DUF2318) K09005 - - 0.0000000000000000000000000000000000000002171 159.0
HKD1_k127_5513249_9 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000006291 134.0
HKD1_k127_5546084_0 HEAT repeats K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 541.0
HKD1_k127_5546084_1 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 524.0
HKD1_k127_5546084_10 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000007397 261.0
HKD1_k127_5546084_11 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 255.0
HKD1_k127_5546084_12 Glycine cleavage system H protein K02437 - - 0.0000000000000000000000000000000000000000000000005432 179.0
HKD1_k127_5546084_13 FCD K05799 - - 0.000000000000000000000000000000000000000000000000945 183.0
HKD1_k127_5546084_14 - - - - 0.000000000000000000000000000000002201 130.0
HKD1_k127_5546084_15 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000001201 114.0
HKD1_k127_5546084_16 4Fe-4S dicluster domain - - - 0.00000000000006636 82.0
HKD1_k127_5546084_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 519.0
HKD1_k127_5546084_3 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 443.0
HKD1_k127_5546084_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 424.0
HKD1_k127_5546084_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 430.0
HKD1_k127_5546084_6 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 417.0
HKD1_k127_5546084_7 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 345.0
HKD1_k127_5546084_8 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 321.0
HKD1_k127_5546084_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 310.0
HKD1_k127_5588048_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 1.319e-200 641.0
HKD1_k127_5588048_1 viral genome integration into host DNA K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 331.0
HKD1_k127_564092_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 361.0
HKD1_k127_564092_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 321.0
HKD1_k127_564092_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 307.0
HKD1_k127_564092_3 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 287.0
HKD1_k127_564092_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004186 267.0
HKD1_k127_564092_5 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001906 266.0
HKD1_k127_564092_6 Domain of unknown function (DUF296) K06934 - - 0.0000000000000004969 84.0
HKD1_k127_5703941_0 DNA photolyase K01669 - 4.1.99.3 4.33e-209 658.0
HKD1_k127_5703941_1 epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 306.0
HKD1_k127_5703941_2 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000001053 151.0
HKD1_k127_5703941_3 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.00000000001398 65.0
HKD1_k127_5703941_4 nucleoside-diphosphate sugar epimerase K07071 - - 0.00000002817 55.0
HKD1_k127_5745994_0 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 405.0
HKD1_k127_5745994_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007449 283.0
HKD1_k127_5800556_0 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 431.0
HKD1_k127_5800556_1 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 313.0
HKD1_k127_5800556_2 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000001789 188.0
HKD1_k127_5800556_3 Ethyl tert-butyl ether degradation EthD - - - 0.00000000000000000001535 94.0
HKD1_k127_5805430_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 550.0
HKD1_k127_5805430_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 379.0
HKD1_k127_5805430_2 Protein of unknown function (DUF2905) - - - 0.00000000000000007747 81.0
HKD1_k127_5874224_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 584.0
HKD1_k127_5874224_1 CoA binding domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 482.0
HKD1_k127_5874224_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 380.0
HKD1_k127_5874224_3 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.000000000000000000000000000000000000000000000000000000000004025 215.0
HKD1_k127_5890774_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.323e-236 746.0
HKD1_k127_5890774_1 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 370.0
HKD1_k127_5890774_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 315.0
HKD1_k127_5890774_3 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000002259 250.0
HKD1_k127_5890774_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004827 246.0
HKD1_k127_5890774_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000005741 190.0
HKD1_k127_5890774_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.00000000000003768 75.0
HKD1_k127_5890774_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000001906 59.0
HKD1_k127_5906613_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 1.734e-230 743.0
HKD1_k127_5906613_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.172e-223 714.0
HKD1_k127_5906613_10 Polysulphide reductase, NrfD - - - 0.000000000001072 79.0
HKD1_k127_5906613_11 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00006612 46.0
HKD1_k127_5906613_12 Bacterial antitoxin of type II TA system, VapB - - - 0.0004308 46.0
HKD1_k127_5906613_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 437.0
HKD1_k127_5906613_3 base-excision repair K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 317.0
HKD1_k127_5906613_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 304.0
HKD1_k127_5906613_5 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003104 286.0
HKD1_k127_5906613_6 4Fe-4S dicluster domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000001025 222.0
HKD1_k127_5906613_7 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000001223 145.0
HKD1_k127_5906613_8 PFAM response regulator receiver - - - 0.000000000000000000000000007834 114.0
HKD1_k127_5906613_9 PIN domain - - - 0.0000000000000002649 83.0
HKD1_k127_59333_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.628e-208 669.0
HKD1_k127_59333_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 514.0
HKD1_k127_59333_10 PFAM ABC transporter related K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 341.0
HKD1_k127_59333_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 291.0
HKD1_k127_59333_12 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009389 270.0
HKD1_k127_59333_13 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004348 249.0
HKD1_k127_59333_14 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000003236 238.0
HKD1_k127_59333_15 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000000000000000000000000000000000000001337 241.0
HKD1_k127_59333_16 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000159 233.0
HKD1_k127_59333_17 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000001929 224.0
HKD1_k127_59333_18 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000002562 209.0
HKD1_k127_59333_19 [acyl-carrier-protein] S-malonyltransferase activity - - - 0.00000000000000000000000000000000000006962 154.0
HKD1_k127_59333_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 501.0
HKD1_k127_59333_20 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000001858 141.0
HKD1_k127_59333_21 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000702 109.0
HKD1_k127_59333_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000006376 71.0
HKD1_k127_59333_3 B12 binding domain K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 488.0
HKD1_k127_59333_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 474.0
HKD1_k127_59333_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 434.0
HKD1_k127_59333_6 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 389.0
HKD1_k127_59333_7 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 392.0
HKD1_k127_59333_8 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 381.0
HKD1_k127_59333_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 359.0
HKD1_k127_6073934_0 GTP-binding protein TypA K06207 - - 5.422e-208 657.0
HKD1_k127_6078085_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.796e-220 687.0
HKD1_k127_6078085_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 613.0
HKD1_k127_6078085_10 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005256 254.0
HKD1_k127_6078085_11 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006219 261.0
HKD1_k127_6078085_12 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000002766 180.0
HKD1_k127_6078085_13 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000005779 171.0
HKD1_k127_6078085_14 Periplasmic binding protein K01999 - - 0.0000000000000000000000000022 126.0
HKD1_k127_6078085_15 Glycine cleavage H-protein - - - 0.0000000000000000000000008518 105.0
HKD1_k127_6078085_16 YsiA-like protein, C-terminal region - - - 0.0000000000000000000000444 108.0
HKD1_k127_6078085_17 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000008217 56.0
HKD1_k127_6078085_2 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 499.0
HKD1_k127_6078085_3 PFAM Acyl-CoA dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 434.0
HKD1_k127_6078085_4 acyl-coa dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 420.0
HKD1_k127_6078085_5 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 342.0
HKD1_k127_6078085_6 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 331.0
HKD1_k127_6078085_7 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 324.0
HKD1_k127_6078085_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 308.0
HKD1_k127_6078085_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000179 291.0
HKD1_k127_6080860_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.0 1090.0
HKD1_k127_6080860_1 PAS domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 585.0
HKD1_k127_6080860_2 4 iron, 4 sulfur cluster binding K03522,K13795,K15511,K19516 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 295.0
HKD1_k127_6080860_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001146 158.0
HKD1_k127_6080860_4 Putative transposon-encoded protein (DUF2080) - - - 0.000000000000003105 77.0
HKD1_k127_6080860_5 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000002497 70.0
HKD1_k127_6090615_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 6.523e-217 700.0
HKD1_k127_6090615_1 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 463.0
HKD1_k127_6090615_10 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000189 150.0
HKD1_k127_6090615_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000001409 141.0
HKD1_k127_6090615_12 - - - - 0.00000000000000000000000000000418 121.0
HKD1_k127_6090615_13 lysyltransferase activity K07027 - - 0.000000000000000000000002568 114.0
HKD1_k127_6090615_14 SH3 domain (SH3b1 type) - - - 0.000000000000000003392 94.0
HKD1_k127_6090615_16 Domain of unknown function (DUF4349) - - - 0.0001189 54.0
HKD1_k127_6090615_2 PFAM MscS Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 363.0
HKD1_k127_6090615_3 NlpC/P60 family K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003056 274.0
HKD1_k127_6090615_4 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 258.0
HKD1_k127_6090615_5 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001081 261.0
HKD1_k127_6090615_6 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000358 246.0
HKD1_k127_6090615_7 DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000000381 197.0
HKD1_k127_6090615_8 Cobalt ABC transporter K02008 - - 0.0000000000000000000000000000000000000000008444 166.0
HKD1_k127_6090615_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000004047 158.0
HKD1_k127_609264_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 594.0
HKD1_k127_609264_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 438.0
HKD1_k127_609264_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 317.0
HKD1_k127_609264_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 283.0
HKD1_k127_609264_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000004497 227.0
HKD1_k127_609264_5 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000005848 151.0
HKD1_k127_609264_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000001094 128.0
HKD1_k127_609264_7 PAC2 family - - - 0.000000000000000000000000001519 121.0
HKD1_k127_609264_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000002156 107.0
HKD1_k127_609264_9 oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000001209 74.0
HKD1_k127_6098696_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009946 295.0
HKD1_k127_6098696_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001513 278.0
HKD1_k127_6098696_2 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005467 267.0
HKD1_k127_6098696_3 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000002972 141.0
HKD1_k127_6098696_4 Belongs to the enoyl-CoA hydratase isomerase family K00074 - 1.1.1.157 0.0000000000000000000000000000001845 128.0
HKD1_k127_6098696_5 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000004061 129.0
HKD1_k127_6137762_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1129.0
HKD1_k127_6137762_1 Protein involved in outer membrane biogenesis - - - 5.385e-301 962.0
HKD1_k127_6137762_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000007956 111.0
HKD1_k127_6137762_11 Psort location CytoplasmicMembrane, score - - - 0.000002883 60.0
HKD1_k127_6137762_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.525e-209 660.0
HKD1_k127_6137762_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 600.0
HKD1_k127_6137762_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 464.0
HKD1_k127_6137762_5 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 439.0
HKD1_k127_6137762_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 402.0
HKD1_k127_6137762_7 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004961 287.0
HKD1_k127_6137762_8 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000005773 222.0
HKD1_k127_6137762_9 COGs COG0655 Multimeric flavodoxin WrbA - - - 0.000000000000000000000000000000000000000000000000007128 186.0
HKD1_k127_6192681_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 578.0
HKD1_k127_6192681_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 551.0
HKD1_k127_6192681_10 - - - - 0.0000000000000000000009729 105.0
HKD1_k127_6192681_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 367.0
HKD1_k127_6192681_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 333.0
HKD1_k127_6192681_4 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
HKD1_k127_6192681_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 313.0
HKD1_k127_6192681_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002147 251.0
HKD1_k127_6192681_7 TIGRFAM maf protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000007771 207.0
HKD1_k127_6192681_8 Fibronectin type 3 domain - - - 0.000000000000000000000000000000003187 142.0
HKD1_k127_6192681_9 Adenylate cyclase - - - 0.00000000000000000000000008409 112.0
HKD1_k127_6251931_0 carbon starvation protein CstA K06200 - - 8.445e-283 878.0
HKD1_k127_6251931_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 580.0
HKD1_k127_6251931_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 537.0
HKD1_k127_6251931_3 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 300.0
HKD1_k127_6251931_4 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000001352 223.0
HKD1_k127_6251931_5 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000003834 200.0
HKD1_k127_6251931_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000002108 186.0
HKD1_k127_6251931_7 - - - - 0.0000000000000000000000000000000000000000000006725 167.0
HKD1_k127_6251931_8 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.00000000000000001478 83.0
HKD1_k127_6251931_9 - - - - 0.0000000003152 63.0
HKD1_k127_6296273_0 PFAM cyclase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 461.0
HKD1_k127_6296273_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 298.0
HKD1_k127_6296273_2 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003412 262.0
HKD1_k127_6296273_3 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
HKD1_k127_6296273_4 - - - - 0.000000000000000000000000000000000000009318 158.0
HKD1_k127_6296273_5 tetratricopeptide repeat - - - 0.0000000000000005292 90.0
HKD1_k127_6296273_6 protein conserved in bacteria - - - 0.0000000000005985 74.0
HKD1_k127_6296273_7 Cytochrome c K00406,K08906 - - 0.000001727 54.0
HKD1_k127_6356405_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 299.0
HKD1_k127_6356405_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000001621 226.0
HKD1_k127_6356405_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000013 151.0
HKD1_k127_6356405_3 OmpA family - - - 0.000000000000000000002688 104.0
HKD1_k127_6356405_4 NADH dehydrogenase K00335 - 1.6.5.3 0.00000000000000000003645 91.0
HKD1_k127_6359486_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 434.0
HKD1_k127_6359486_1 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 391.0
HKD1_k127_6359486_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 305.0
HKD1_k127_6359486_3 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006329 279.0
HKD1_k127_6359486_4 Fumarate K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000102 261.0
HKD1_k127_6359486_5 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000003678 242.0
HKD1_k127_6359486_6 carboxylase K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000000000008816 159.0
HKD1_k127_6359486_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000002921 138.0
HKD1_k127_6376044_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 549.0
HKD1_k127_6376044_1 Alginate O-acetylation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 550.0
HKD1_k127_6376044_2 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 288.0
HKD1_k127_6376044_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 261.0
HKD1_k127_6376044_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000006239 227.0
HKD1_k127_6376044_5 PIN domain - - - 0.000000000000000000000000000000000000000000000009363 175.0
HKD1_k127_6376044_6 Thioesterase superfamily - - - 0.0000000000000000000000000000003324 127.0
HKD1_k127_6376044_8 Outer membrane lipoprotein - - - 0.00000000000000000000000134 119.0
HKD1_k127_6376044_9 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000002884 50.0
HKD1_k127_6405064_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
HKD1_k127_6405064_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 386.0
HKD1_k127_6405064_2 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 311.0
HKD1_k127_6405064_3 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000004521 259.0
HKD1_k127_6405064_4 transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000155 227.0
HKD1_k127_6405064_5 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000001544 79.0
HKD1_k127_6457942_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 490.0
HKD1_k127_6457942_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 480.0
HKD1_k127_6457942_2 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 329.0
HKD1_k127_6457942_3 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000003674 173.0
HKD1_k127_6457942_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000002256 140.0
HKD1_k127_6457942_5 Thioredoxin-like - - - 0.000000000000000000000000000000000005576 144.0
HKD1_k127_6457942_6 GDYXXLXY protein - - - 0.00000000000000001536 91.0
HKD1_k127_6471011_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 435.0
HKD1_k127_6471011_1 BadF BadG BcrA BcrD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 406.0
HKD1_k127_6471011_10 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000141 219.0
HKD1_k127_6471011_11 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000796 212.0
HKD1_k127_6471011_12 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000137 171.0
HKD1_k127_6471011_13 Domain of unknown function (DUF3842) - - - 0.000000000000000000000000000000000000000002062 162.0
HKD1_k127_6471011_14 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000001679 154.0
HKD1_k127_6471011_15 Membrane - - - 0.0000000000000000000000000000000000001627 151.0
HKD1_k127_6471011_16 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000000000001966 140.0
HKD1_k127_6471011_17 Predicted RNA-binding protein - - - 0.000000000000000006561 85.0
HKD1_k127_6471011_18 PDGLE domain K02009 - - 0.00000000000000003479 93.0
HKD1_k127_6471011_19 - - - - 0.000000000000005783 88.0
HKD1_k127_6471011_2 tungstate binding K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 361.0
HKD1_k127_6471011_20 4 iron, 4 sulfur cluster binding K00205,K02573 - - 0.000006727 48.0
HKD1_k127_6471011_21 transglycosylase K08307 - - 0.000007295 55.0
HKD1_k127_6471011_22 Transposase K07483 - - 0.00003284 48.0
HKD1_k127_6471011_3 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 358.0
HKD1_k127_6471011_4 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 308.0
HKD1_k127_6471011_5 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002126 274.0
HKD1_k127_6471011_6 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
HKD1_k127_6471011_7 molybdate abc transporter K02018,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
HKD1_k127_6471011_8 ATPase activity K02017,K15497 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000001964 254.0
HKD1_k127_6471011_9 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000002663 226.0
HKD1_k127_6476205_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 470.0
HKD1_k127_6476205_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 409.0
HKD1_k127_6476205_2 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.00000000000000000000000001252 115.0
HKD1_k127_6476205_3 cell redox homeostasis - - - 0.00000000000000000000000006582 108.0
HKD1_k127_6547079_0 7TM-HD extracellular K07037 - - 4.359e-195 634.0
HKD1_k127_6547079_1 AAA domain K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 439.0
HKD1_k127_6547079_2 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001333 267.0
HKD1_k127_6547079_3 PFAM Nitroreductase - - - 0.0000000000000000000000000000000009645 137.0
HKD1_k127_6547079_4 serine threonine protein kinase - - - 0.000000000000000000000000002907 119.0
HKD1_k127_6547079_5 Uncharacterized protein family UPF0054 K07042 - - 0.0000000000000000000000311 105.0
HKD1_k127_655458_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1114.0
HKD1_k127_655458_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 498.0
HKD1_k127_655458_11 PFAM carboxyl transferase K01615 - 4.1.1.70 0.00000000001306 66.0
HKD1_k127_655458_2 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 354.0
HKD1_k127_655458_3 PFAM iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 321.0
HKD1_k127_655458_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 280.0
HKD1_k127_655458_5 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001148 256.0
HKD1_k127_655458_6 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005583 250.0
HKD1_k127_655458_7 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000761 233.0
HKD1_k127_655458_8 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000001069 165.0
HKD1_k127_655458_9 SCP-2 sterol transfer family - - - 0.0000000000000000000000306 104.0
HKD1_k127_6555196_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 559.0
HKD1_k127_6555196_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 383.0
HKD1_k127_6555196_2 PIN domain - - - 0.000000000000000000000000000003892 124.0
HKD1_k127_6555196_3 PFAM SpoVT AbrB - - - 0.0000000000000000002748 89.0
HKD1_k127_6571978_0 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 358.0
HKD1_k127_6571978_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 351.0
HKD1_k127_6571978_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002002 259.0
HKD1_k127_6571978_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000003993 67.0
HKD1_k127_6571978_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.000001215 54.0
HKD1_k127_6571978_5 Protein of unknown function (DUF1059) - - - 0.000051 49.0
HKD1_k127_6571978_6 Periplasmic Protein K09914 - - 0.0001872 48.0
HKD1_k127_6583835_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 9.375e-320 985.0
HKD1_k127_6583835_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 464.0
HKD1_k127_6583835_2 Staphylopine dehydrogenase K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006464 276.0
HKD1_k127_6583835_3 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000002061 132.0
HKD1_k127_6595922_0 von Willebrand factor, type A K07114 - - 2.23e-308 962.0
HKD1_k127_6595922_1 CoA-transferase family III - - - 7.297e-200 629.0
HKD1_k127_6595922_10 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000002065 231.0
HKD1_k127_6595922_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000001273 182.0
HKD1_k127_6595922_12 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000007652 186.0
HKD1_k127_6595922_13 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000006971 156.0
HKD1_k127_6595922_14 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000001896 160.0
HKD1_k127_6595922_16 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000002815 125.0
HKD1_k127_6595922_17 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000127 122.0
HKD1_k127_6595922_19 Transcriptional regulatory protein, C terminal K02483,K07658,K07668 - - 0.000000000000000000000003008 117.0
HKD1_k127_6595922_2 Two component signalling adaptor domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 428.0
HKD1_k127_6595922_20 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000006891 99.0
HKD1_k127_6595922_21 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.0000000000000000005479 93.0
HKD1_k127_6595922_23 PHP domain protein - - - 0.0000008099 59.0
HKD1_k127_6595922_3 acetyltransferase K19113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 410.0
HKD1_k127_6595922_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 334.0
HKD1_k127_6595922_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 305.0
HKD1_k127_6595922_6 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 297.0
HKD1_k127_6595922_7 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000282 289.0
HKD1_k127_6595922_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004825 284.0
HKD1_k127_6595922_9 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000003155 248.0
HKD1_k127_6599830_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005999 278.0
HKD1_k127_6599830_1 4Fe-4S binding domain K02572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004373 250.0
HKD1_k127_6633420_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.666e-265 831.0
HKD1_k127_6633420_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.596e-225 711.0
HKD1_k127_6633420_10 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 317.0
HKD1_k127_6633420_11 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 312.0
HKD1_k127_6633420_12 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 294.0
HKD1_k127_6633420_13 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 289.0
HKD1_k127_6633420_14 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004084 278.0
HKD1_k127_6633420_15 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000003053 235.0
HKD1_k127_6633420_16 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000003106 221.0
HKD1_k127_6633420_17 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000537 210.0
HKD1_k127_6633420_18 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000003041 195.0
HKD1_k127_6633420_19 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000001265 175.0
HKD1_k127_6633420_2 Bacterial transcriptional activator domain - - - 4.566e-223 729.0
HKD1_k127_6633420_20 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000002945 159.0
HKD1_k127_6633420_21 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000007332 158.0
HKD1_k127_6633420_22 Belongs to the ComB family K05979 - 3.1.3.71 0.00000000000000000000000000000483 123.0
HKD1_k127_6633420_23 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000000006465 124.0
HKD1_k127_6633420_24 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000003224 119.0
HKD1_k127_6633420_25 PIN domain - - - 0.00000000000000000000000001012 113.0
HKD1_k127_6633420_27 hydrolase - - - 0.000000000000000001919 98.0
HKD1_k127_6633420_28 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000002346 76.0
HKD1_k127_6633420_29 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000003837 69.0
HKD1_k127_6633420_3 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 3.224e-216 696.0
HKD1_k127_6633420_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.238e-196 631.0
HKD1_k127_6633420_5 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 611.0
HKD1_k127_6633420_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 583.0
HKD1_k127_6633420_7 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 506.0
HKD1_k127_6633420_8 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 409.0
HKD1_k127_6633420_9 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 335.0
HKD1_k127_6637977_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.436e-213 667.0
HKD1_k127_6637977_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 476.0
HKD1_k127_6637977_2 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 315.0
HKD1_k127_6637977_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
HKD1_k127_6637977_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000206 194.0
HKD1_k127_6637977_5 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000007625 108.0
HKD1_k127_6659317_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01615 - 4.1.1.70 7.198e-298 919.0
HKD1_k127_6659317_1 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
HKD1_k127_6659317_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000005197 179.0
HKD1_k127_6659317_3 identical protein binding K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.000000000000000000000000000004687 126.0
HKD1_k127_6671786_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1087.0
HKD1_k127_6671786_1 ABC transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 462.0
HKD1_k127_6671786_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 314.0
HKD1_k127_6671786_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 307.0
HKD1_k127_6671786_4 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000001123 245.0
HKD1_k127_6671786_5 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000008938 211.0
HKD1_k127_6671786_6 exodeoxyribonuclease I activity - - - 0.0000000000000002567 80.0
HKD1_k127_6679695_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 442.0
HKD1_k127_6679695_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 363.0
HKD1_k127_6679695_10 4Fe-4S binding domain - - - 0.00000000000000006333 83.0
HKD1_k127_6679695_2 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 360.0
HKD1_k127_6679695_3 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 342.0
HKD1_k127_6679695_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 310.0
HKD1_k127_6679695_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 285.0
HKD1_k127_6679695_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002811 254.0
HKD1_k127_6679695_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000005016 221.0
HKD1_k127_6679695_8 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000002574 178.0
HKD1_k127_6679695_9 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000007693 181.0
HKD1_k127_6740901_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 416.0
HKD1_k127_6740901_1 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
HKD1_k127_6740901_10 Acetyltransferase (GNAT) domain - - - 0.0006317 43.0
HKD1_k127_6740901_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 321.0
HKD1_k127_6740901_3 transferase hexapeptide K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004857 274.0
HKD1_k127_6740901_4 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000007082 152.0
HKD1_k127_6740901_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000001599 147.0
HKD1_k127_6740901_6 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000001602 118.0
HKD1_k127_6740901_7 polysaccharide biosynthetic process - - - 0.000000000000000000001663 108.0
HKD1_k127_6740901_8 PFAM Glycosyl transferases group 1 - - - 0.00000000000001755 85.0
HKD1_k127_6740901_9 Acetyltransferase (GNAT) domain - - - 0.000003874 53.0
HKD1_k127_6756400_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 563.0
HKD1_k127_6756400_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 381.0
HKD1_k127_6756400_10 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000002578 104.0
HKD1_k127_6756400_11 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.0000000000000000000002603 98.0
HKD1_k127_6756400_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 332.0
HKD1_k127_6756400_3 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
HKD1_k127_6756400_4 amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 287.0
HKD1_k127_6756400_5 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004414 286.0
HKD1_k127_6756400_6 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
HKD1_k127_6756400_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000007602 209.0
HKD1_k127_6756400_8 Protein of unknown function (DUF1648) - - - 0.00000000000000000000000000000000000113 144.0
HKD1_k127_6756400_9 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000000000000000000001763 115.0
HKD1_k127_6780040_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 3.694e-235 747.0
HKD1_k127_6780040_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 554.0
HKD1_k127_6780040_10 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 364.0
HKD1_k127_6780040_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
HKD1_k127_6780040_12 COGs COG1144 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase delta subunit K00171,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000004343 208.0
HKD1_k127_6780040_13 Regulatory protein GntR HTH K05799 - - 0.000000000000000000000000000000000000000002088 164.0
HKD1_k127_6780040_14 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000008518 162.0
HKD1_k127_6780040_15 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000001104 158.0
HKD1_k127_6780040_16 regulatory protein GntR HTH - - - 0.000000000000000000000000000004592 131.0
HKD1_k127_6780040_17 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000001648 114.0
HKD1_k127_6780040_18 4Fe-4S dicluster domain - - - 0.00000000000000000000000001224 114.0
HKD1_k127_6780040_19 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000001007 106.0
HKD1_k127_6780040_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 545.0
HKD1_k127_6780040_20 Transglutaminase-like superfamily - - - 0.0000000000000000000001072 102.0
HKD1_k127_6780040_21 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000001326 89.0
HKD1_k127_6780040_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 515.0
HKD1_k127_6780040_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 466.0
HKD1_k127_6780040_5 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 468.0
HKD1_k127_6780040_6 ABC-type multidrug transport system ATPase and permease K06147,K06148,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 427.0
HKD1_k127_6780040_7 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 398.0
HKD1_k127_6780040_8 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 407.0
HKD1_k127_6780040_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 372.0
HKD1_k127_6921879_0 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 466.0
HKD1_k127_6921879_1 CHAT domain - - - 0.000000000000000000000000000000000000003472 154.0
HKD1_k127_6921879_2 CHAT domain - - - 0.0000000000000000000000000000000002569 152.0
HKD1_k127_6921879_3 - - - - 0.000000002741 69.0
HKD1_k127_7013990_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 375.0
HKD1_k127_7013990_1 Membrane - - - 0.0000000000000000000000000000000001097 142.0
HKD1_k127_7013990_2 PFAM OmpA MotB domain protein - - - 0.0000000000000000000000000000000007888 138.0
HKD1_k127_7013990_3 PFAM FecR protein - - - 0.00000000000000000000000000000001405 132.0
HKD1_k127_7013990_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000347 137.0
HKD1_k127_7013990_5 nucleotide-binding protein containing TIR -like domain - - - 0.0000000000000000000000000002001 127.0
HKD1_k127_7013990_7 3D domain - - - 0.000006919 55.0
HKD1_k127_7013990_8 Helix-turn-helix domain - - - 0.00004516 48.0
HKD1_k127_7018036_0 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 338.0
HKD1_k127_7018036_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 316.0
HKD1_k127_7018036_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
HKD1_k127_7018036_3 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000003087 125.0
HKD1_k127_7047146_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 265.0
HKD1_k127_7058268_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 524.0
HKD1_k127_7058268_1 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 506.0
HKD1_k127_7058268_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 501.0
HKD1_k127_7058268_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000001736 169.0
HKD1_k127_7058268_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000001486 142.0
HKD1_k127_7058770_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 594.0
HKD1_k127_7058770_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 471.0
HKD1_k127_7058770_10 LETM1-like protein - - - 0.00000009611 60.0
HKD1_k127_7058770_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009773 340.0
HKD1_k127_7058770_3 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 320.0
HKD1_k127_7058770_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 290.0
HKD1_k127_7058770_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000002583 236.0
HKD1_k127_7058770_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000001722 205.0
HKD1_k127_7058770_7 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000000629 197.0
HKD1_k127_7058770_8 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000002538 192.0
HKD1_k127_7058770_9 curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000008612 144.0
HKD1_k127_7070271_0 Major intrinsic protein K06188 - - 0.00000000000000000000005135 99.0
HKD1_k127_7070271_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000006458 60.0
HKD1_k127_7070271_2 - - - - 0.000005866 54.0
HKD1_k127_7070271_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00005972 45.0
HKD1_k127_7072582_0 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 454.0
HKD1_k127_7072582_1 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 381.0
HKD1_k127_7072582_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00395 - 1.8.99.2 0.000158 45.0
HKD1_k127_7095763_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 529.0
HKD1_k127_7095763_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 350.0
HKD1_k127_7095763_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 333.0
HKD1_k127_7095763_3 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 308.0
HKD1_k127_7095763_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
HKD1_k127_7095763_5 - - - - 0.000000000000000000000000009582 111.0
HKD1_k127_7095763_6 PFAM Class III cytochrome C family - - - 0.0000000000000002459 83.0
HKD1_k127_7113887_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 527.0
HKD1_k127_7113887_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 509.0
HKD1_k127_7113887_10 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002734 249.0
HKD1_k127_7113887_11 PFAM MaoC domain protein dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000109 192.0
HKD1_k127_7113887_12 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000005958 195.0
HKD1_k127_7113887_13 polynucleotide 5'-hydroxyl-kinase activity K06947 - - 0.00000000000000000000000000000000000001076 156.0
HKD1_k127_7113887_14 Coenzyme A transferase K01026 - 2.8.3.1 0.0007844 42.0
HKD1_k127_7113887_2 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 360.0
HKD1_k127_7113887_3 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 348.0
HKD1_k127_7113887_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 350.0
HKD1_k127_7113887_5 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 299.0
HKD1_k127_7113887_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 300.0
HKD1_k127_7113887_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002271 278.0
HKD1_k127_7113887_8 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 265.0
HKD1_k127_7113887_9 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002149 249.0
HKD1_k127_7119478_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1777.0
HKD1_k127_7119478_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000002712 213.0
HKD1_k127_7119478_2 Calcineurin-like phosphoesterase superfamily domain K07096 - - 0.00000000000000000000000000000000000000000000000004333 189.0
HKD1_k127_713411_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 424.0
HKD1_k127_713411_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001836 244.0
HKD1_k127_713411_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000007826 152.0
HKD1_k127_713411_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000001038 108.0
HKD1_k127_713411_4 Nitroreductase family - - - 0.0000000000000000000008028 96.0
HKD1_k127_7134841_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.766e-248 780.0
HKD1_k127_7134841_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 6.767e-209 660.0
HKD1_k127_7134841_10 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 448.0
HKD1_k127_7134841_11 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 407.0
HKD1_k127_7134841_12 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 380.0
HKD1_k127_7134841_13 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 368.0
HKD1_k127_7134841_14 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 342.0
HKD1_k127_7134841_15 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 340.0
HKD1_k127_7134841_16 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 336.0
HKD1_k127_7134841_17 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 311.0
HKD1_k127_7134841_18 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002447 285.0
HKD1_k127_7134841_19 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
HKD1_k127_7134841_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.696e-208 671.0
HKD1_k127_7134841_20 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001827 263.0
HKD1_k127_7134841_21 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000001975 269.0
HKD1_k127_7134841_22 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 266.0
HKD1_k127_7134841_23 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006293 259.0
HKD1_k127_7134841_24 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000002211 240.0
HKD1_k127_7134841_25 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519,K13479 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000952 240.0
HKD1_k127_7134841_26 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000004939 235.0
HKD1_k127_7134841_27 - K01992,K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000004684 229.0
HKD1_k127_7134841_28 PFAM Xylose - - - 0.0000000000000000000000000000000000000000000000000000000000004028 221.0
HKD1_k127_7134841_29 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000007047 202.0
HKD1_k127_7134841_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 8.487e-198 641.0
HKD1_k127_7134841_30 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000003379 195.0
HKD1_k127_7134841_31 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000004188 169.0
HKD1_k127_7134841_32 MFS transporter - - - 0.00000000000000000000000000000000000000000003208 173.0
HKD1_k127_7134841_33 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000001996 162.0
HKD1_k127_7134841_34 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000000000008747 154.0
HKD1_k127_7134841_35 - - - - 0.00000000000000000000000000000000005734 138.0
HKD1_k127_7134841_36 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000247 135.0
HKD1_k127_7134841_37 ParB-like nuclease domain - - - 0.00000000000000000000000000000001447 132.0
HKD1_k127_7134841_38 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000003587 125.0
HKD1_k127_7134841_39 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.00000000000000000000000000001765 125.0
HKD1_k127_7134841_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 614.0
HKD1_k127_7134841_40 Domain of unknown function (DUF5058) - - - 0.00000000000000000000000000003389 125.0
HKD1_k127_7134841_41 ACT domain - - - 0.0000000000000000000000000002157 122.0
HKD1_k127_7134841_42 - - - - 0.00000000000000000003278 100.0
HKD1_k127_7134841_43 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000002709 92.0
HKD1_k127_7134841_44 - - - - 0.0000000000000000004591 89.0
HKD1_k127_7134841_45 TonB C terminal K03832 - - 0.00000000000000001448 94.0
HKD1_k127_7134841_46 Tripartite tricarboxylate transporter TctB family - - - 0.0000000002551 67.0
HKD1_k127_7134841_47 Tautomerase enzyme K01821 - 5.3.2.6 0.00000001572 58.0
HKD1_k127_7134841_48 - - - - 0.0002298 44.0
HKD1_k127_7134841_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 601.0
HKD1_k127_7134841_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 499.0
HKD1_k127_7134841_7 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 487.0
HKD1_k127_7134841_8 4fe-4S ferredoxin, iron-sulfur binding domain protein K00244,K20449 - 1.3.5.4,1.3.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 477.0
HKD1_k127_7134841_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 456.0
HKD1_k127_7152629_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000001242 173.0
HKD1_k127_7152629_1 pfam nudix K03574 - 3.6.1.55 0.00000000000000000000000000000005233 130.0
HKD1_k127_7152629_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0004132 44.0
HKD1_k127_7165809_0 Bacterial extracellular solute-binding protein K02012 - - 5.698e-198 621.0
HKD1_k127_7165809_1 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 427.0
HKD1_k127_7165809_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 351.0
HKD1_k127_7165809_3 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
HKD1_k127_7165809_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000002479 187.0
HKD1_k127_7165809_5 molybdopterin binding domain - - - 0.0000000000002778 72.0
HKD1_k127_7176633_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 603.0
HKD1_k127_7176633_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006571 238.0
HKD1_k127_7176633_10 TIGRFAM redox-active disulfide protein 2 - - - 0.00000000000000000005365 91.0
HKD1_k127_7176633_11 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000003495 87.0
HKD1_k127_7176633_12 - - - - 0.00000000000000007318 83.0
HKD1_k127_7176633_13 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.000000000001243 70.0
HKD1_k127_7176633_2 DGC domain - - - 0.0000000000000000000000000000000000000000000000000000001098 198.0
HKD1_k127_7176633_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000006524 182.0
HKD1_k127_7176633_4 DGC domain - - - 0.00000000000000000000000000000000000000000000000652 175.0
HKD1_k127_7176633_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000009399 158.0
HKD1_k127_7176633_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.0000000000000000000000000000000001866 139.0
HKD1_k127_7176633_7 Putative Fe-S cluster - - - 0.000000000000000000000000000000001757 136.0
HKD1_k127_7176633_8 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.000000000000000000000000000001554 128.0
HKD1_k127_7176633_9 Thioredoxin domain - - - 0.0000000000000000000000004888 110.0
HKD1_k127_7183443_0 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 584.0
HKD1_k127_7183443_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000001751 152.0
HKD1_k127_7186894_0 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002073 254.0
HKD1_k127_7186894_1 Belongs to the protease inhibitor I11 (ecotin) family K08276 - - 0.000000000000000000000000000000000000000000000000000000000000002563 220.0
HKD1_k127_7186894_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000003722 168.0
HKD1_k127_7186894_3 - - - - 0.0000000000000000000000000000000000000009867 149.0
HKD1_k127_7186894_4 Methylamine utilisation protein MauE - - - 0.000000000001611 74.0
HKD1_k127_7186894_5 TIGRFAM C_GCAxxG_C_C family - - - 0.000000002643 63.0
HKD1_k127_7186894_6 general stress protein - - - 0.00006222 50.0
HKD1_k127_72072_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 547.0
HKD1_k127_72072_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 509.0
HKD1_k127_72072_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 367.0
HKD1_k127_72072_3 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 325.0
HKD1_k127_72072_4 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 300.0
HKD1_k127_72072_5 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000111 238.0
HKD1_k127_72072_6 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000005379 192.0
HKD1_k127_72072_7 pfam nlp p60 - - - 0.0000000000000000000000000000000000000000000000000658 187.0
HKD1_k127_72072_8 - - - - 0.000000002263 64.0
HKD1_k127_7212071_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.741e-239 752.0
HKD1_k127_7212071_1 PFAM Pyruvate carboxyltransferase - - - 7.026e-211 662.0
HKD1_k127_7212071_10 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002896 210.0
HKD1_k127_7212071_11 GAF domain - - - 0.00000000000000000000000000000000000000000000000000003499 211.0
HKD1_k127_7212071_12 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000001522 177.0
HKD1_k127_7212071_14 - - - - 0.000000000000000000000000007338 111.0
HKD1_k127_7212071_15 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000008632 124.0
HKD1_k127_7212071_16 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000007467 102.0
HKD1_k127_7212071_17 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000001546 101.0
HKD1_k127_7212071_18 Domain of unknown function (DUF1858) - - - 0.000000000000000000000589 96.0
HKD1_k127_7212071_19 - - - - 0.0000000000000000005499 91.0
HKD1_k127_7212071_2 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 461.0
HKD1_k127_7212071_20 Cupin domain - - - 0.000000000003032 71.0
HKD1_k127_7212071_21 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000002863 62.0
HKD1_k127_7212071_3 CoA binding domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 422.0
HKD1_k127_7212071_4 Bacterial regulatory protein, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 395.0
HKD1_k127_7212071_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 287.0
HKD1_k127_7212071_6 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001831 280.0
HKD1_k127_7212071_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000001253 226.0
HKD1_k127_7212071_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002928 220.0
HKD1_k127_7212071_9 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000001678 218.0
HKD1_k127_7215752_0 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 370.0
HKD1_k127_7215752_1 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 361.0
HKD1_k127_7215752_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000002409 242.0
HKD1_k127_7215752_3 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
HKD1_k127_7246283_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.822e-294 919.0
HKD1_k127_7246283_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 487.0
HKD1_k127_7246283_10 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002393 244.0
HKD1_k127_7246283_11 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000002664 201.0
HKD1_k127_7246283_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000008978 136.0
HKD1_k127_7246283_13 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000004746 99.0
HKD1_k127_7246283_14 nuclear chromosome segregation - - - 0.0000000009447 65.0
HKD1_k127_7246283_15 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000003503 58.0
HKD1_k127_7246283_2 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 387.0
HKD1_k127_7246283_3 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 374.0
HKD1_k127_7246283_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 364.0
HKD1_k127_7246283_5 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 360.0
HKD1_k127_7246283_6 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 342.0
HKD1_k127_7246283_7 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 333.0
HKD1_k127_7246283_8 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
HKD1_k127_7246283_9 PP-loop family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HKD1_k127_7246306_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.757e-216 680.0
HKD1_k127_7246306_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 389.0
HKD1_k127_7246306_10 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000004169 177.0
HKD1_k127_7246306_11 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000003206 157.0
HKD1_k127_7246306_2 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 347.0
HKD1_k127_7246306_3 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 309.0
HKD1_k127_7246306_4 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 297.0
HKD1_k127_7246306_5 antibiotic catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 304.0
HKD1_k127_7246306_6 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005788 244.0
HKD1_k127_7246306_8 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000005035 205.0
HKD1_k127_7246306_9 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000003619 173.0
HKD1_k127_728947_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 542.0
HKD1_k127_728947_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000007611 145.0
HKD1_k127_728947_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000004286 78.0
HKD1_k127_7302265_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 473.0
HKD1_k127_7302265_1 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 404.0
HKD1_k127_7302265_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000009548 181.0
HKD1_k127_7302265_11 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000354 152.0
HKD1_k127_7302265_13 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000001288 143.0
HKD1_k127_7302265_14 Sigma-54 interaction domain - - - 0.000000000000000000000000000343 119.0
HKD1_k127_7302265_15 - - - - 0.00000000000004755 80.0
HKD1_k127_7302265_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 367.0
HKD1_k127_7302265_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005841 287.0
HKD1_k127_7302265_4 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000765 257.0
HKD1_k127_7302265_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000005557 193.0
HKD1_k127_7302265_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000009292 210.0
HKD1_k127_7302265_7 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000004089 187.0
HKD1_k127_7302265_8 Diguanylate cyclase with GAF sensor - - - 0.000000000000000000000000000000000000000000000000197 190.0
HKD1_k127_7302265_9 COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.000000000000000000000000000000000000000000000001936 187.0
HKD1_k127_7304884_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 494.0
HKD1_k127_7304884_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
HKD1_k127_7304884_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007809 268.0
HKD1_k127_7341631_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 584.0
HKD1_k127_7341631_1 Arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 404.0
HKD1_k127_7341631_2 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 347.0
HKD1_k127_7341631_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000002937 188.0
HKD1_k127_7341631_4 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000007198 184.0
HKD1_k127_7341631_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000004095 146.0
HKD1_k127_7341631_6 ThiS family K03636 - - 0.0000000000000000000000000001893 121.0
HKD1_k127_7344119_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1232.0
HKD1_k127_7344119_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 2.048e-229 718.0
HKD1_k127_7344119_10 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 542.0
HKD1_k127_7344119_11 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 539.0
HKD1_k127_7344119_12 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 519.0
HKD1_k127_7344119_13 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 471.0
HKD1_k127_7344119_14 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 450.0
HKD1_k127_7344119_15 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 429.0
HKD1_k127_7344119_16 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 419.0
HKD1_k127_7344119_17 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 399.0
HKD1_k127_7344119_18 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 386.0
HKD1_k127_7344119_19 Glycosyl transferase family 2 K00721,K10012 - 2.4.1.83,2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 385.0
HKD1_k127_7344119_2 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 1.683e-225 717.0
HKD1_k127_7344119_20 histidine kinase, HAMP K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 387.0
HKD1_k127_7344119_21 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 352.0
HKD1_k127_7344119_22 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 355.0
HKD1_k127_7344119_23 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 338.0
HKD1_k127_7344119_24 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 346.0
HKD1_k127_7344119_25 response regulator K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 311.0
HKD1_k127_7344119_26 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
HKD1_k127_7344119_27 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 316.0
HKD1_k127_7344119_28 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007191 274.0
HKD1_k127_7344119_29 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001506 266.0
HKD1_k127_7344119_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.138e-217 691.0
HKD1_k127_7344119_30 tRNA 3'-trailer cleavage - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004006 253.0
HKD1_k127_7344119_31 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000497 243.0
HKD1_k127_7344119_32 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000004824 238.0
HKD1_k127_7344119_33 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
HKD1_k127_7344119_34 8-oxoguanine DNA glycosylase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000009259 221.0
HKD1_k127_7344119_35 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000002582 196.0
HKD1_k127_7344119_36 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000002016 175.0
HKD1_k127_7344119_37 Methyltransferase domain - - - 0.00000000000000000000000000000000000000009135 160.0
HKD1_k127_7344119_38 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000003574 157.0
HKD1_k127_7344119_39 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000003385 104.0
HKD1_k127_7344119_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.887e-215 680.0
HKD1_k127_7344119_40 Tetratricopeptide repeat-like domain - - - 0.000000000000001175 85.0
HKD1_k127_7344119_41 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000003676 71.0
HKD1_k127_7344119_42 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000005326 75.0
HKD1_k127_7344119_43 TPR repeat - - - 0.000001026 62.0
HKD1_k127_7344119_44 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000009226 58.0
HKD1_k127_7344119_45 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00002743 57.0
HKD1_k127_7344119_5 General secretory system II, protein E domain protein K02652 - - 3.095e-213 678.0
HKD1_k127_7344119_6 PFAM asparagine synthase K01953 - 6.3.5.4 4.548e-195 627.0
HKD1_k127_7344119_7 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 627.0
HKD1_k127_7344119_8 Elongation factor Tu domain 2 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 610.0
HKD1_k127_7344119_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 584.0
HKD1_k127_7358484_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1181.0
HKD1_k127_7358484_1 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 8.069e-275 857.0
HKD1_k127_7358484_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
HKD1_k127_7358484_11 heme binding - - - 0.00000000000000000000000000000000000000000004194 169.0
HKD1_k127_7358484_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000966 159.0
HKD1_k127_7358484_13 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000008758 151.0
HKD1_k127_7358484_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000005248 136.0
HKD1_k127_7358484_15 helix_turn_helix, mercury resistance - - - 0.000000000000000000000003576 106.0
HKD1_k127_7358484_16 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000002679 85.0
HKD1_k127_7358484_17 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.0000000000000002336 79.0
HKD1_k127_7358484_18 Belongs to the UPF0145 family - - - 0.000000000009171 71.0
HKD1_k127_7358484_2 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.097e-241 766.0
HKD1_k127_7358484_3 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 6.593e-240 765.0
HKD1_k127_7358484_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 460.0
HKD1_k127_7358484_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 400.0
HKD1_k127_7358484_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 297.0
HKD1_k127_7358484_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 286.0
HKD1_k127_7358484_9 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000004157 241.0
HKD1_k127_7373905_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 573.0
HKD1_k127_7373905_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 531.0
HKD1_k127_7373905_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 391.0
HKD1_k127_7373905_3 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000002435 159.0
HKD1_k127_7373905_4 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000002691 158.0
HKD1_k127_7373905_5 PFAM AAA ATPase central domain protein K06027 - 3.6.4.6 0.000000000000000000000000000000000001369 141.0
HKD1_k127_7373905_7 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000032 122.0
HKD1_k127_7373905_8 - - - - 0.000000000000829 82.0
HKD1_k127_7373936_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 589.0
HKD1_k127_7373936_1 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000004509 154.0
HKD1_k127_7373936_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000005524 149.0
HKD1_k127_7373936_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002958 122.0
HKD1_k127_7373936_4 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.000008642 52.0
HKD1_k127_7395817_0 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 376.0
HKD1_k127_7395817_1 Low affinity iron permease - - - 0.000000000000000000000000000000000000000000000002016 177.0
HKD1_k127_7395817_2 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000005237 159.0
HKD1_k127_7395817_3 Membrane - - - 0.000000000000000000000000000008197 124.0
HKD1_k127_7395817_4 - - - - 0.000000000000000006038 85.0
HKD1_k127_7395817_5 - - - - 0.000000000000002162 77.0
HKD1_k127_7395817_6 Protein of unknown function (DUF3568) - - - 0.00000000002897 70.0
HKD1_k127_7395817_8 Protein of unknown function (DUF3096) - - - 0.00000009838 55.0
HKD1_k127_742074_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001348 259.0
HKD1_k127_742074_1 Rubrerythrin - - - 0.000000000000000000000000001513 117.0
HKD1_k127_742074_2 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000007796 98.0
HKD1_k127_742074_3 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000858 68.0
HKD1_k127_7423230_0 AMP-binding enzyme C-terminal domain - - - 1.018e-227 709.0
HKD1_k127_7423230_1 Cys/Met metabolism PLP-dependent enzyme K01758,K01761 - 4.4.1.1,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 546.0
HKD1_k127_7423230_10 SpoVT / AbrB like domain K07172 - - 0.0000000000000000000000000003151 115.0
HKD1_k127_7423230_12 - - - - 0.000000000000000000001432 98.0
HKD1_k127_7423230_13 - - - - 0.000000000000000000007641 98.0
HKD1_k127_7423230_14 - - - - 0.0000002805 57.0
HKD1_k127_7423230_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 523.0
HKD1_k127_7423230_3 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 449.0
HKD1_k127_7423230_4 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 380.0
HKD1_k127_7423230_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 354.0
HKD1_k127_7423230_6 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004803 242.0
HKD1_k127_7423230_7 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002065 235.0
HKD1_k127_7423230_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000000000000000843 185.0
HKD1_k127_7423230_9 - - - - 0.0000000000000000000000000000000000008302 140.0
HKD1_k127_7450657_0 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1481.0
HKD1_k127_7450657_1 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 540.0
HKD1_k127_7450657_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 423.0
HKD1_k127_7450657_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 319.0
HKD1_k127_7450657_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 298.0
HKD1_k127_7450657_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 264.0
HKD1_k127_7450657_6 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000004254 197.0
HKD1_k127_7450657_7 B3 4 domain protein - - - 0.00000000000002583 81.0
HKD1_k127_7450657_8 Tautomerase enzyme K01821 - 5.3.2.6 0.0000002742 54.0
HKD1_k127_74555_0 6-phosphogluconate dehydrogenase-like protein K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 345.0
HKD1_k127_74555_1 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway K00068,K18124,K18125 GO:0000166,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005515,GO:0005534,GO:0005536,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006012,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019320,GO:0019388,GO:0019595,GO:0022607,GO:0030246,GO:0033498,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046430,GO:0046872,GO:0046914,GO:0046983,GO:0047910,GO:0047936,GO:0048029,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.140,1.1.1.359,1.1.1.360 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 310.0
HKD1_k127_74555_2 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000003591 209.0
HKD1_k127_74555_3 PFAM cyclase family protein K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000001358 178.0
HKD1_k127_747504_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 447.0
HKD1_k127_747504_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 364.0
HKD1_k127_747504_2 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000005416 155.0
HKD1_k127_747504_3 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000003744 100.0
HKD1_k127_7532180_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1028.0
HKD1_k127_7532180_1 Domain of unknown function (DUF4301) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 555.0
HKD1_k127_7532180_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000004226 235.0
HKD1_k127_7532180_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000003303 226.0
HKD1_k127_7532180_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
HKD1_k127_7532180_5 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000005641 213.0
HKD1_k127_7532180_6 Phosphodiester glycosidase - - - 0.00000000000000000003178 93.0
HKD1_k127_7571761_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 294.0
HKD1_k127_7571761_1 Domain of unknown function (DUF697) - - - 0.000000000000000000000000000000000000000000000000000002302 204.0
HKD1_k127_7571761_2 NUDIX hydrolase - - - 0.00000001956 58.0
HKD1_k127_7583454_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 461.0
HKD1_k127_7583454_1 RNA recognition motif - - - 0.00000000000000000000000000003103 119.0
HKD1_k127_7627483_0 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 306.0
HKD1_k127_7627483_1 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001009 252.0
HKD1_k127_7627483_10 PFAM response regulator receiver - - - 0.00000000000000000000000000002664 123.0
HKD1_k127_7627483_11 Protein of unknown function (DUF1059) - - - 0.000000000000000000000009071 101.0
HKD1_k127_7627483_12 cog cog2801 K07497 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000008921 96.0
HKD1_k127_7627483_13 endonuclease containing a URI domain K07461 - - 0.00000000000000000003019 93.0
HKD1_k127_7627483_14 - - - - 0.0000000001698 70.0
HKD1_k127_7627483_15 Lipocalin-like domain - - - 0.0000003329 55.0
HKD1_k127_7627483_2 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005143 246.0
HKD1_k127_7627483_3 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001108 239.0
HKD1_k127_7627483_4 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001578 227.0
HKD1_k127_7627483_5 serine-type peptidase activity K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000789 228.0
HKD1_k127_7627483_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000001773 192.0
HKD1_k127_7627483_7 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000005082 168.0
HKD1_k127_7627483_8 Haem-degrading - - - 0.00000000000000000000000000000000000000002564 156.0
HKD1_k127_7627483_9 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000001414 132.0
HKD1_k127_7640063_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 582.0
HKD1_k127_7640063_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 427.0
HKD1_k127_7640063_10 Universal stress protein family - - - 0.000000000000000000444 93.0
HKD1_k127_7640063_11 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000002815 78.0
HKD1_k127_7640063_12 - - - - 0.000002712 57.0
HKD1_k127_7640063_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 387.0
HKD1_k127_7640063_3 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 308.0
HKD1_k127_7640063_4 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 301.0
HKD1_k127_7640063_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000006211 246.0
HKD1_k127_7640063_6 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000006176 217.0
HKD1_k127_7640063_7 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000005117 192.0
HKD1_k127_7640063_8 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000000000000000000001559 196.0
HKD1_k127_7640063_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000009123 136.0
HKD1_k127_7686493_0 Large extracellular alpha-helical protein K06894 - - 0.0 2121.0
HKD1_k127_7686493_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.024e-207 667.0
HKD1_k127_7686493_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002551 255.0
HKD1_k127_7686493_3 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000001103 160.0
HKD1_k127_7686493_4 alpha-ribazole phosphatase activity K01834,K15634,K22306 - 3.1.3.85,5.4.2.11,5.4.2.12 0.00000000000000000000000000000000000001187 152.0
HKD1_k127_7743041_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 477.0
HKD1_k127_7743041_1 Hydrogenase expression formation protein (HypE) K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008653 278.0
HKD1_k127_7743041_2 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000001657 208.0
HKD1_k127_7743041_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000006233 198.0
HKD1_k127_7743041_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000005372 166.0
HKD1_k127_7743041_5 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000005565 178.0
HKD1_k127_7743041_6 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000769 104.0
HKD1_k127_7743041_7 - - - - 0.000000000000000001343 87.0
HKD1_k127_78008_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 5.023e-242 754.0
HKD1_k127_78008_1 CoA-substrate-specific enzyme activase - - - 1.57e-232 769.0
HKD1_k127_78008_10 Bax inhibitor 1 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 327.0
HKD1_k127_78008_11 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 304.0
HKD1_k127_78008_12 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003622 292.0
HKD1_k127_78008_13 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007793 258.0
HKD1_k127_78008_14 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006568 255.0
HKD1_k127_78008_15 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000002869 233.0
HKD1_k127_78008_18 dehydratase - - - 0.0000000001283 66.0
HKD1_k127_78008_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 1.277e-210 668.0
HKD1_k127_78008_3 Aminotransferase class-III K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 2.375e-206 649.0
HKD1_k127_78008_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 557.0
HKD1_k127_78008_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 451.0
HKD1_k127_78008_6 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 360.0
HKD1_k127_78008_7 Iron-containing alcohol dehydrogenase K19954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 359.0
HKD1_k127_78008_8 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 346.0
HKD1_k127_78008_9 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 346.0
HKD1_k127_7806014_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 480.0
HKD1_k127_7806014_1 carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 423.0
HKD1_k127_7806014_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 380.0
HKD1_k127_7806014_3 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000003852 204.0
HKD1_k127_7806014_4 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.0000000000000000000000005772 109.0
HKD1_k127_7806014_5 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000001006 99.0
HKD1_k127_7806014_6 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000006382 83.0
HKD1_k127_7854186_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 531.0
HKD1_k127_7854186_1 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 355.0
HKD1_k127_7854186_2 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000001247 171.0
HKD1_k127_7877195_0 Belongs to the glycosyl hydrolase 57 family K06044 - 5.4.99.15 0.0 1011.0
HKD1_k127_7877195_1 cell redox homeostasis - - - 4.283e-227 712.0
HKD1_k127_7877195_10 Protein of unknown function (DUF3309) - - - 0.00000000001644 67.0
HKD1_k127_7877195_11 ChaB K06197 - - 0.00000000004067 64.0
HKD1_k127_7877195_12 Protein of unknown function (DUF1328) - - - 0.00000000009301 63.0
HKD1_k127_7877195_2 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 554.0
HKD1_k127_7877195_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 304.0
HKD1_k127_7877195_4 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 294.0
HKD1_k127_7877195_5 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000893 274.0
HKD1_k127_7877195_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000001496 168.0
HKD1_k127_7877195_8 - - - - 0.00000000000000001087 85.0
HKD1_k127_7877195_9 - - - - 0.00000000000000001581 83.0
HKD1_k127_7925040_0 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 354.0
HKD1_k127_7925040_1 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001967 275.0
HKD1_k127_7925040_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000001296 229.0
HKD1_k127_7925040_3 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000001081 203.0
HKD1_k127_7925040_4 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000000000000000000103 161.0
HKD1_k127_7925040_5 PLD-like domain - - - 0.00000000000000000000001041 107.0
HKD1_k127_7925040_6 methyltransferase activity - - - 0.0000000000000000000003591 102.0
HKD1_k127_7925040_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000003478 86.0
HKD1_k127_79814_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 410.0
HKD1_k127_79814_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000009692 147.0
HKD1_k127_79814_2 diguanylate cyclase K02488 - 2.7.7.65 0.0000000006485 70.0
HKD1_k127_8028933_0 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 504.0
HKD1_k127_8028933_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003309 256.0
HKD1_k127_8028933_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000001271 168.0
HKD1_k127_8028933_3 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000000005726 147.0
HKD1_k127_83209_0 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 298.0
HKD1_k127_83209_1 response regulator - - - 0.0000000000000000000000000000000000000002168 153.0
HKD1_k127_83209_2 AhpC/TSA family - - - 0.000000000000000000000000000000000000004638 153.0
HKD1_k127_83209_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000003235 143.0
HKD1_k127_83209_4 PFAM GAF domain - - - 0.0000000000000000000000000000000002701 135.0
HKD1_k127_83209_5 cheY-homologous receiver domain - - - 0.000000000000000000004852 97.0
HKD1_k127_83209_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 - - 0.0009642 46.0
HKD1_k127_883217_0 Asparagine synthase K01953 - 6.3.5.4 2.679e-317 981.0
HKD1_k127_883217_1 COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 567.0
HKD1_k127_883217_10 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000001936 244.0
HKD1_k127_883217_11 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002719 246.0
HKD1_k127_883217_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000001198 232.0
HKD1_k127_883217_13 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000006009 203.0
HKD1_k127_883217_14 Methyltransferase domain - - - 0.00000000000000000000000000000000000000001202 161.0
HKD1_k127_883217_15 Sigma-54 interaction domain K07714 - - 0.0000001186 53.0
HKD1_k127_883217_2 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 486.0
HKD1_k127_883217_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 424.0
HKD1_k127_883217_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 415.0
HKD1_k127_883217_5 Membrane protein involved in the export of o-antigen and teichoic acid K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 326.0
HKD1_k127_883217_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 303.0
HKD1_k127_883217_7 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
HKD1_k127_883217_8 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004973 288.0
HKD1_k127_883217_9 transferase activity, transferring amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004724 278.0
HKD1_k127_94138_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1085.0
HKD1_k127_94138_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000001507 228.0
HKD1_k127_94138_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000008155 183.0
HKD1_k127_94138_3 23S rRNA-intervening sequence protein - - - 0.00000000000005045 77.0
HKD1_k127_94138_4 Protein of unknown function (DUF2905) - - - 0.0000001319 53.0
HKD1_k127_96295_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 317.0
HKD1_k127_96295_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000005513 181.0
HKD1_k127_96295_2 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.0000000000000000000000000000003379 139.0
HKD1_k127_96295_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000003475 90.0
HKD1_k127_96295_4 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000004958 55.0
HKD1_k127_96416_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 394.0
HKD1_k127_96416_1 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 351.0