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Overview

ID MAG01768
Name HKD1_bin.88
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order UBA7656
Family UBA7656
Genus JADGNW01
Species
Assembly information
Completeness (%) 61.84
Contamination (%) 0.87
GC content (%) 58.0
N50 (bp) 4,323
Genome size (bp) 3,469,023

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2994

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1008956_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 303.0
HKD1_k127_1008956_1 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000004766 149.0
HKD1_k127_1017849_0 cellulose binding - - - 9.289e-209 662.0
HKD1_k127_1023771_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 1.612e-318 998.0
HKD1_k127_1023771_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 485.0
HKD1_k127_1023771_2 SnoaL-like domain - - - 0.00000000005294 68.0
HKD1_k127_1023771_3 Chaperone protein dnaJ K03686 - - 0.000003382 59.0
HKD1_k127_1033667_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000008167 68.0
HKD1_k127_1033667_1 signal transduction histidine kinase - - - 0.00001617 50.0
HKD1_k127_1034122_0 Carboxypeptidase regulatory-like domain - - - 0.0 1502.0
HKD1_k127_1034122_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 381.0
HKD1_k127_1034122_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 354.0
HKD1_k127_1034122_3 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000003766 137.0
HKD1_k127_1034122_4 Pyruvate phosphate dikinase - - - 0.0000000000000000000331 94.0
HKD1_k127_1035499_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 372.0
HKD1_k127_1038529_0 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004118 271.0
HKD1_k127_1038529_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
HKD1_k127_1038529_2 CarD-like/TRCF domain K07736 - - 0.0000000000000000001122 93.0
HKD1_k127_1038992_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 582.0
HKD1_k127_1038992_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 372.0
HKD1_k127_1038992_2 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 377.0
HKD1_k127_1038992_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 318.0
HKD1_k127_1052233_0 ASPIC and UnbV - - - 1.525e-245 766.0
HKD1_k127_1052233_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 367.0
HKD1_k127_1053244_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001674 310.0
HKD1_k127_1053244_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000001438 175.0
HKD1_k127_1053244_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000001573 152.0
HKD1_k127_1053244_3 PDZ DHR GLGF domain protein - - - 0.000000000000000000000004305 115.0
HKD1_k127_1053244_4 Ion transport 2 domain protein K10716 - - 0.000000000000001298 80.0
HKD1_k127_105795_0 PFAM NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 423.0
HKD1_k127_105795_1 AntiSigma factor - - - 0.0000000000000000000000000000000000000001664 163.0
HKD1_k127_105795_2 DoxX-like family - - - 0.0000000000000000000000000000000002785 138.0
HKD1_k127_105795_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000001225 51.0
HKD1_k127_1068054_0 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 335.0
HKD1_k127_1068054_1 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000006856 66.0
HKD1_k127_1070198_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 353.0
HKD1_k127_1070198_1 Serine aminopeptidase, S33 K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 312.0
HKD1_k127_1070198_2 Metalloenzyme superfamily K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 297.0
HKD1_k127_1070198_3 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 299.0
HKD1_k127_1070198_4 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000008517 267.0
HKD1_k127_1070198_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000009595 212.0
HKD1_k127_1070198_6 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000004638 131.0
HKD1_k127_1070198_7 - - - - 0.00003698 55.0
HKD1_k127_1091423_0 PFAM Type II secretion system protein E K02652 - - 1.013e-209 665.0
HKD1_k127_1091423_1 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009857 267.0
HKD1_k127_1091423_2 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000003297 214.0
HKD1_k127_1091423_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000009569 187.0
HKD1_k127_1091423_4 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000005078 153.0
HKD1_k127_1091423_5 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000002998 113.0
HKD1_k127_1091423_6 Belongs to the GSP D family - - - 0.00000000000000000001131 108.0
HKD1_k127_1091423_7 Protein of unknown function (DUF465) - - - 0.00000006821 57.0
HKD1_k127_1091423_8 Pilus assembly protein - - - 0.0000002389 62.0
HKD1_k127_1091423_9 Metallo-peptidase family M12B Reprolysin-like - - - 0.0002569 51.0
HKD1_k127_1098522_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 554.0
HKD1_k127_1098522_1 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 324.0
HKD1_k127_1098522_2 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
HKD1_k127_1098522_3 Sporulation initiation inhibitor Soj K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000001327 130.0
HKD1_k127_1098522_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00006825 53.0
HKD1_k127_11019_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 580.0
HKD1_k127_11019_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 424.0
HKD1_k127_11019_2 competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008015 231.0
HKD1_k127_11019_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000003256 206.0
HKD1_k127_11019_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000002137 189.0
HKD1_k127_11019_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000989 176.0
HKD1_k127_11019_6 dUTPase K01494 - 3.5.4.13 0.0000000000000003482 78.0
HKD1_k127_1113670_0 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 470.0
HKD1_k127_1113670_1 Coagulation factor 5 8 type domain protein K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 408.0
HKD1_k127_1116004_0 Peptidase dimerisation domain - - - 1.243e-205 652.0
HKD1_k127_1116004_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 342.0
HKD1_k127_1116004_2 myo-inosose-2 dehydratase activity - - - 0.00000002456 59.0
HKD1_k127_1119143_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 603.0
HKD1_k127_1119143_1 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 569.0
HKD1_k127_1119143_2 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 369.0
HKD1_k127_1119143_3 Peptidase M16 inactive domain K07263 - - 0.00009476 53.0
HKD1_k127_1120288_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 371.0
HKD1_k127_1120288_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000009769 233.0
HKD1_k127_1120288_2 DinB superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000003992 188.0
HKD1_k127_1120288_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000007132 164.0
HKD1_k127_1120288_4 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000026 115.0
HKD1_k127_1122261_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 342.0
HKD1_k127_1123877_0 CHASE3 domain - - - 1.319e-247 786.0
HKD1_k127_1123877_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 311.0
HKD1_k127_1123877_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000003362 193.0
HKD1_k127_1123877_4 - - - - 0.0005553 49.0
HKD1_k127_1132425_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 496.0
HKD1_k127_1132425_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000505 205.0
HKD1_k127_1132425_2 regulation of DNA repair K03565 - - 0.0000000005413 68.0
HKD1_k127_1132425_3 in signal transduction K08482 - - 0.00000002829 66.0
HKD1_k127_1132425_4 Domain of unknown function (DUF4388) - - - 0.000009616 55.0
HKD1_k127_1142081_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006602 288.0
HKD1_k127_1142081_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000006655 119.0
HKD1_k127_1150431_0 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 289.0
HKD1_k127_1150431_1 Domain of unknown function (DUF1287) K09974 - - 0.0000000000000000000000000000000000000000000000000000000000004576 218.0
HKD1_k127_1150431_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000006976 79.0
HKD1_k127_1151344_0 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 602.0
HKD1_k127_1151344_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 600.0
HKD1_k127_1155833_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 548.0
HKD1_k127_1155833_1 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 286.0
HKD1_k127_1156258_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1145.0
HKD1_k127_1168109_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 403.0
HKD1_k127_1168109_1 - - - - 0.0000000000000000000000000000000000000000009979 162.0
HKD1_k127_1168109_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000004859 154.0
HKD1_k127_116965_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000008283 241.0
HKD1_k127_1170722_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000001097 177.0
HKD1_k127_1170722_1 deoxyhypusine monooxygenase activity K05385 - - 0.000000000000000000000000000000000000000000002562 179.0
HKD1_k127_1170722_2 HEAT repeats - - - 0.00000000000000000000000000000000000000000001534 181.0
HKD1_k127_1175580_0 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000125 124.0
HKD1_k127_1176088_0 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 468.0
HKD1_k127_1176088_1 PAS domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000008225 220.0
HKD1_k127_1226015_0 symbiont process K00612 - - 0.0000000000000000000000000000000000006681 148.0
HKD1_k127_1249624_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 394.0
HKD1_k127_1249624_2 amine dehydrogenase activity - - - 0.00000000000000000000000000002133 124.0
HKD1_k127_1249624_3 YCII-related domain - - - 0.000000000000000000001355 104.0
HKD1_k127_1249624_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000002923 90.0
HKD1_k127_1281929_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 395.0
HKD1_k127_1281929_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000002041 180.0
HKD1_k127_1281929_2 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000005436 180.0
HKD1_k127_1281929_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000006098 146.0
HKD1_k127_1298579_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 431.0
HKD1_k127_1298579_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
HKD1_k127_1298579_2 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001337 245.0
HKD1_k127_1298579_3 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000001348 139.0
HKD1_k127_1299973_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 419.0
HKD1_k127_1299973_1 Peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 348.0
HKD1_k127_1299973_2 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000007616 215.0
HKD1_k127_1299973_3 MobA-like NTP transferase domain - - - 0.0000000000000000000000000005284 119.0
HKD1_k127_1299973_4 COG0526 Thiol-disulfide isomerase and thioredoxins - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0003186 50.0
HKD1_k127_130734_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 549.0
HKD1_k127_130734_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 461.0
HKD1_k127_130734_2 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 435.0
HKD1_k127_130734_3 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 299.0
HKD1_k127_130734_4 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000003928 155.0
HKD1_k127_130734_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000008515 88.0
HKD1_k127_1313782_0 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 313.0
HKD1_k127_1313782_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003752 277.0
HKD1_k127_1313782_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000003149 249.0
HKD1_k127_1313782_3 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000003398 196.0
HKD1_k127_1314588_0 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 406.0
HKD1_k127_1314588_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 417.0
HKD1_k127_1314588_2 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 286.0
HKD1_k127_1318535_0 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000754 175.0
HKD1_k127_1321304_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 472.0
HKD1_k127_1321304_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001152 287.0
HKD1_k127_1321304_2 Ribonucleotide reductase, all-alpha domain K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000179 248.0
HKD1_k127_1326916_0 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 428.0
HKD1_k127_1326916_1 cAMP biosynthetic process - - - 0.00000000001631 66.0
HKD1_k127_1326916_2 Belongs to the peptidase S16 family K07177 - - 0.00004968 51.0
HKD1_k127_1328254_0 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 566.0
HKD1_k127_1328254_1 Pfam Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 544.0
HKD1_k127_1328254_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 439.0
HKD1_k127_1328254_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000005329 176.0
HKD1_k127_1328254_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000004632 140.0
HKD1_k127_1341043_0 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000001678 153.0
HKD1_k127_1341043_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000007634 64.0
HKD1_k127_1341043_2 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000001288 66.0
HKD1_k127_1342094_0 DEAD DEAH box helicase K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 503.0
HKD1_k127_1342094_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 402.0
HKD1_k127_1342094_2 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000003477 64.0
HKD1_k127_1342094_3 - - - - 0.0000000007846 66.0
HKD1_k127_1342094_4 - - - - 0.0009594 44.0
HKD1_k127_1347320_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000001298 182.0
HKD1_k127_1347320_1 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.00000000000000000000000000000118 130.0
HKD1_k127_1357348_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 414.0
HKD1_k127_1357348_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 385.0
HKD1_k127_1357348_2 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000004714 93.0
HKD1_k127_1357348_3 NosL - - - 0.000000000000947 76.0
HKD1_k127_1369458_0 Oligogalacturonate lyase K01730 - 4.2.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 425.0
HKD1_k127_1369458_1 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 0.000000000000000000000000000000000000000000000000002023 184.0
HKD1_k127_1369458_2 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.0000000000000000000000000000000000000000001229 169.0
HKD1_k127_1369458_3 hydrolase, family 65, central catalytic - - - 0.0000000000000000000000000000004659 126.0
HKD1_k127_1370389_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003444 235.0
HKD1_k127_1381135_0 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000009831 211.0
HKD1_k127_1381135_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000004043 188.0
HKD1_k127_1381135_2 Methyltransferase domain - - - 0.00000000000000000000000008473 115.0
HKD1_k127_1395556_0 - - - - 0.00000000000000000000000000000000000004114 159.0
HKD1_k127_1395556_1 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000009853 132.0
HKD1_k127_1395556_2 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000233 116.0
HKD1_k127_1400333_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 538.0
HKD1_k127_1400333_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 340.0
HKD1_k127_1400333_2 Protein of unknown function (DUF1175) K09934 - - 0.00000000000000000000000000000000000000000000000000000001175 210.0
HKD1_k127_1400333_3 - - - - 0.0000000000000001958 87.0
HKD1_k127_1400333_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000012 76.0
HKD1_k127_1400333_5 Tetratricopeptide repeat - - - 0.0000009179 55.0
HKD1_k127_1404512_0 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000272 199.0
HKD1_k127_1417201_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000142 178.0
HKD1_k127_1425898_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007894 272.0
HKD1_k127_1432580_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 406.0
HKD1_k127_1432580_1 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000009789 115.0
HKD1_k127_1435097_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007043 277.0
HKD1_k127_1435097_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000008875 244.0
HKD1_k127_1435097_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000001423 217.0
HKD1_k127_1435097_3 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000000000000000000000000000000000000005639 180.0
HKD1_k127_1435097_4 chaperone-mediated protein folding - - - 0.00000000000000000000000000000001176 145.0
HKD1_k127_1435097_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000008318 128.0
HKD1_k127_144597_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 601.0
HKD1_k127_144597_1 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000001644 86.0
HKD1_k127_1457119_0 Putative glucoamylase K13688 - - 0.0 1509.0
HKD1_k127_1457119_1 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 1.666e-255 805.0
HKD1_k127_1457119_2 PFAM sulfatase - - - 0.0003671 48.0
HKD1_k127_1469788_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 434.0
HKD1_k127_1469788_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000009301 179.0
HKD1_k127_1469788_2 Phosphocarrier protein HPr K08485,K11189 - - 0.000000000000000000001109 98.0
HKD1_k127_1520297_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 410.0
HKD1_k127_1520297_1 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000001085 171.0
HKD1_k127_1545483_0 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 394.0
HKD1_k127_1545483_1 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 298.0
HKD1_k127_1545483_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000004962 206.0
HKD1_k127_1545483_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000001969 135.0
HKD1_k127_154932_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000682 144.0
HKD1_k127_154932_1 AntiSigma factor - - - 0.0002773 49.0
HKD1_k127_1564615_0 ATPase associated with K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000001217 234.0
HKD1_k127_1564615_1 DinB superfamily - - - 0.0000000000000000005266 93.0
HKD1_k127_1565742_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 344.0
HKD1_k127_1565742_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 310.0
HKD1_k127_1565742_2 CYTH - - - 0.0003947 51.0
HKD1_k127_1571007_0 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 392.0
HKD1_k127_1576879_0 Spermidine putrescine-binding periplasmic protein K11069,K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 340.0
HKD1_k127_1577298_0 PFAM Prolyl oligopeptidase family - - - 7.951e-279 871.0
HKD1_k127_1577298_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 417.0
HKD1_k127_1577298_2 - - - - 0.000000000000000000000000000000000000000000000000001983 188.0
HKD1_k127_1579276_0 Radical SAM - - - 0.0 1219.0
HKD1_k127_1579276_1 (ABC) transporter K06147,K18890 - - 1.014e-203 651.0
HKD1_k127_1579276_2 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 564.0
HKD1_k127_1579276_3 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 473.0
HKD1_k127_1580162_0 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005307 279.0
HKD1_k127_1580162_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
HKD1_k127_1580162_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000287 168.0
HKD1_k127_1587836_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 4.957e-200 636.0
HKD1_k127_1587836_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001385 214.0
HKD1_k127_1587836_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000002377 97.0
HKD1_k127_1614586_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1401.0
HKD1_k127_1614586_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 413.0
HKD1_k127_1614586_2 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 362.0
HKD1_k127_1614586_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000971 207.0
HKD1_k127_1614586_4 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000155 179.0
HKD1_k127_1614586_5 lysyltransferase activity K07027 - - 0.000000000000000000002501 106.0
HKD1_k127_1614586_6 GYD domain - - - 0.000000005864 62.0
HKD1_k127_1618944_0 Psort location Cytoplasmic, score 8.96 K03653 - 4.2.99.18 0.000000000000000000000000000000000002761 146.0
HKD1_k127_1618944_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000001046 91.0
HKD1_k127_1618944_2 Aspartyl protease - - - 0.00000000000000001288 97.0
HKD1_k127_1621270_0 efflux transmembrane transporter activity K02004 - - 2.637e-196 640.0
HKD1_k127_1621270_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 437.0
HKD1_k127_1624995_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1199.0
HKD1_k127_1642551_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
HKD1_k127_1642551_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000001794 66.0
HKD1_k127_1642551_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000000006333 65.0
HKD1_k127_1649533_0 N-acetylglucosaminylinositol deacetylase activity K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 497.0
HKD1_k127_1649533_1 von Willebrand factor, type A - - - 0.000003925 57.0
HKD1_k127_1654129_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 401.0
HKD1_k127_1654129_1 efflux transmembrane transporter activity K02004 - - 0.0000003704 53.0
HKD1_k127_1655970_0 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000001194 172.0
HKD1_k127_1655970_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000001041 90.0
HKD1_k127_1658973_0 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 7.317e-202 638.0
HKD1_k127_1658973_1 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 445.0
HKD1_k127_1658973_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000004546 195.0
HKD1_k127_1658973_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000003523 193.0
HKD1_k127_1658973_4 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000000002267 136.0
HKD1_k127_1662951_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1027.0
HKD1_k127_1662951_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000001736 108.0
HKD1_k127_1671906_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 334.0
HKD1_k127_1671906_1 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000003343 219.0
HKD1_k127_1671906_2 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000002892 175.0
HKD1_k127_1671906_3 - K12065 - - 0.0000000000000000000000000000002058 142.0
HKD1_k127_1671906_4 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000376 122.0
HKD1_k127_1671906_5 Two component regulator propeller - - - 0.00000000002493 75.0
HKD1_k127_1673216_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1022.0
HKD1_k127_1673216_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 389.0
HKD1_k127_1673216_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 352.0
HKD1_k127_1673216_3 peptidoglycan-binding domain-containing protein K17733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001662 280.0
HKD1_k127_1673216_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000001802 246.0
HKD1_k127_1673216_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001371 211.0
HKD1_k127_1673216_6 succinate dehydrogenase K00241,K00247 - - 0.00000000000000000000000000000000000000000000000000005785 194.0
HKD1_k127_1681458_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 2.195e-227 712.0
HKD1_k127_1681458_1 TROVE domain - - - 1.91e-210 665.0
HKD1_k127_1681458_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 381.0
HKD1_k127_1681458_3 - - - - 0.00009429 51.0
HKD1_k127_1681510_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 569.0
HKD1_k127_1681510_1 - - - - 0.000000000000000000000000000000000000003985 153.0
HKD1_k127_1681510_2 PFAM microcompartments protein K04027 - - 0.00000000000000000000000000000000001 139.0
HKD1_k127_1681510_3 Helix-turn-helix domain - - - 0.000000000000008696 85.0
HKD1_k127_1681510_4 TIGRFAM acetaldehyde dehydrogenase (acetylating) - - - 0.0000000001513 63.0
HKD1_k127_1688598_0 NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 428.0
HKD1_k127_1688598_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 381.0
HKD1_k127_1688598_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 371.0
HKD1_k127_1702945_0 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 460.0
HKD1_k127_1702945_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 262.0
HKD1_k127_1705713_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 600.0
HKD1_k127_1719229_0 Belongs to the peptidase M16 family K07263 - - 1.452e-253 814.0
HKD1_k127_1725076_0 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 310.0
HKD1_k127_1725076_1 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000136 250.0
HKD1_k127_1725076_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001885 219.0
HKD1_k127_1740197_0 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 2.668e-222 703.0
HKD1_k127_1740197_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000995 194.0
HKD1_k127_1740197_2 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000002074 181.0
HKD1_k127_1744380_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 292.0
HKD1_k127_1744380_1 thiolester hydrolase activity K07000 - - 0.0000000000000000000000000000000000000000000000172 181.0
HKD1_k127_1744380_2 DinB family - - - 0.00000000000000000000000007941 115.0
HKD1_k127_1744380_3 Beta-lactamase - - - 0.000000000004723 74.0
HKD1_k127_1744380_4 hyperosmotic response - - - 0.000000008747 64.0
HKD1_k127_1748028_0 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 490.0
HKD1_k127_1748028_1 PFAM peptidase C14, caspase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 396.0
HKD1_k127_175280_0 cellulose binding - - - 4.74e-229 718.0
HKD1_k127_175280_1 Protein tyrosine kinase - - - 5.805e-210 682.0
HKD1_k127_175280_2 HsdM N-terminal domain K03427 - 2.1.1.72 0.000000000001086 70.0
HKD1_k127_1754321_0 alpha-galactosidase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 308.0
HKD1_k127_1754321_1 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009208 273.0
HKD1_k127_1754321_2 Glycerophosphoryl diester phosphodiesterase family K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000003424 199.0
HKD1_k127_1755802_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000034 173.0
HKD1_k127_1769286_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 579.0
HKD1_k127_1769286_1 C-terminal, D2-small domain, of ClpB protein K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 375.0
HKD1_k127_1769286_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000001229 184.0
HKD1_k127_1769286_3 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000004634 147.0
HKD1_k127_1769286_4 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000008988 106.0
HKD1_k127_1769286_5 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000001822 107.0
HKD1_k127_1777941_0 Belongs to the ompA family - - - 0.00000000000000000000000000000004977 138.0
HKD1_k127_178396_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 1.486e-198 624.0
HKD1_k127_178396_1 Thioredoxin domain - - - 0.0000000000000000000000000000000000000002539 155.0
HKD1_k127_178396_2 - - - - 0.00000000000000000000000000000000000001669 149.0
HKD1_k127_178396_3 oxidoreductase activity - - - 0.0000000000000000000000000000000000004707 144.0
HKD1_k127_178396_4 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.0000000000000000000003111 102.0
HKD1_k127_178396_5 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000261 96.0
HKD1_k127_178396_6 Thioredoxin domain - - - 0.0000000000000000001575 89.0
HKD1_k127_178396_7 - - - - 0.000000000000000000516 96.0
HKD1_k127_1793124_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 2.246e-285 885.0
HKD1_k127_1793124_1 PFAM Type II IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 429.0
HKD1_k127_1793124_2 PFAM Type II IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 380.0
HKD1_k127_1832174_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1208.0
HKD1_k127_1832174_1 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 393.0
HKD1_k127_1832174_2 F5 8 type C domain protein K01206 - 3.2.1.51 0.000000000000000000000000000000000001003 142.0
HKD1_k127_1839977_0 Histidine kinase K02660,K03406,K11525 - - 0.0000000000000000000000000000000000000000000000000000000000003128 222.0
HKD1_k127_1839977_1 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000005166 135.0
HKD1_k127_1862949_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 452.0
HKD1_k127_1862949_1 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 433.0
HKD1_k127_1862949_2 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.0000000000000000000000009107 111.0
HKD1_k127_1866391_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000001575 220.0
HKD1_k127_1866391_1 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000002529 212.0
HKD1_k127_1879114_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 499.0
HKD1_k127_1879114_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 379.0
HKD1_k127_1879114_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000001518 142.0
HKD1_k127_1896093_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 290.0
HKD1_k127_1896093_1 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000008729 145.0
HKD1_k127_1896093_2 chlorophyll binding - - - 0.000000000000000000000001347 112.0
HKD1_k127_1913263_0 - - - - 0.0000000000000000000000000000000000000000000000001468 195.0
HKD1_k127_1929747_0 Stage II sporulation D domain protein K06381 - - 0.00000000000000000000000000000000000000000000000000006926 211.0
HKD1_k127_1929747_1 Alpha-2-Macroglobulin K06894 - - 0.0000000000000000000000000003686 119.0
HKD1_k127_1950481_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 327.0
HKD1_k127_1950481_1 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000005224 222.0
HKD1_k127_1950481_2 ABC-type uncharacterized transport system - - - 0.000000000000000000000002991 109.0
HKD1_k127_1963227_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 442.0
HKD1_k127_1963227_1 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006911 284.0
HKD1_k127_1963681_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 398.0
HKD1_k127_1963681_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 302.0
HKD1_k127_1963681_2 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000004832 151.0
HKD1_k127_1967174_0 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 436.0
HKD1_k127_1967174_1 - - - - 0.000000000000000000000000000000000000000000000003323 188.0
HKD1_k127_1967174_2 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000003527 177.0
HKD1_k127_1967174_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001452 155.0
HKD1_k127_196723_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000002177 159.0
HKD1_k127_196723_1 - - - - 0.00000000000000000000000000000000000000001297 161.0
HKD1_k127_196723_2 - - - - 0.00000000000000000000000000000000000000002541 153.0
HKD1_k127_196723_3 - - - - 0.00000000000000000000000000000000000000005496 159.0
HKD1_k127_196723_4 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000002425 142.0
HKD1_k127_196723_5 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000003427 130.0
HKD1_k127_196723_6 BNR repeat-like domain K05989 - 3.2.1.40 0.00000001881 57.0
HKD1_k127_1975000_0 Domain of unknown function (DUF4252) - - - 0.0000000000000000000000000000000001177 141.0
HKD1_k127_1983022_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 605.0
HKD1_k127_1983022_1 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 312.0
HKD1_k127_1983022_2 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000008363 136.0
HKD1_k127_1983022_3 Redoxin - - - 0.0000001286 56.0
HKD1_k127_1993431_0 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 535.0
HKD1_k127_1993431_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 531.0
HKD1_k127_1993431_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001919 202.0
HKD1_k127_2000592_0 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 503.0
HKD1_k127_2000592_1 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000008068 243.0
HKD1_k127_2000592_2 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000003781 212.0
HKD1_k127_2000592_3 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000001917 151.0
HKD1_k127_2000592_4 PFAM TfoX N-terminal domain K07343 - - 0.00000000000000000000000000000008356 127.0
HKD1_k127_2000592_5 - - - - 0.00000001143 61.0
HKD1_k127_2004379_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 4.059e-254 796.0
HKD1_k127_2011656_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1061.0
HKD1_k127_2011656_1 transcriptional regulator K21900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 303.0
HKD1_k127_2011656_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000005866 239.0
HKD1_k127_2011656_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000391 123.0
HKD1_k127_2011656_4 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000006792 84.0
HKD1_k127_2014559_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000002416 241.0
HKD1_k127_2014559_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000002151 71.0
HKD1_k127_2024413_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 510.0
HKD1_k127_2024413_1 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.00000000000000000000000000000000000001039 147.0
HKD1_k127_2024413_2 EthD domain - - - 0.0000000000000000000000000000000000001642 143.0
HKD1_k127_2024413_3 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.00000000000000000000000001273 114.0
HKD1_k127_2047201_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 509.0
HKD1_k127_204742_0 Elongator protein 3, MiaB family, Radical SAM K04034 - 1.21.98.3 7.276e-220 689.0
HKD1_k127_204742_1 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 496.0
HKD1_k127_204742_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000001338 173.0
HKD1_k127_204742_3 DNA-templated transcription, initiation - - - 0.000000005532 59.0
HKD1_k127_2060375_0 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 319.0
HKD1_k127_2060375_1 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000002242 215.0
HKD1_k127_2060375_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000002408 115.0
HKD1_k127_208053_0 Protein of unknown function (DUF1553) - - - 7.377e-218 695.0
HKD1_k127_208053_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000001592 100.0
HKD1_k127_2088284_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 309.0
HKD1_k127_2088284_1 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000007842 224.0
HKD1_k127_2088284_2 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000006574 190.0
HKD1_k127_2088284_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000001367 164.0
HKD1_k127_2088284_4 thiolester hydrolase activity K17362 - - 0.0000000000005695 70.0
HKD1_k127_2088284_5 PFAM sigma-70 region 2 domain protein K03088 - - 0.00001474 53.0
HKD1_k127_2089088_0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 400.0
HKD1_k127_2089088_1 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 295.0
HKD1_k127_2089088_2 Belongs to the UPF0102 family K07460 - - 0.00000000000009381 78.0
HKD1_k127_2092986_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.195e-224 706.0
HKD1_k127_2092986_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 424.0
HKD1_k127_2092986_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 392.0
HKD1_k127_2092986_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 356.0
HKD1_k127_2092986_4 Yip1 domain - - - 0.0000001645 62.0
HKD1_k127_2099408_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 561.0
HKD1_k127_2099408_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 521.0
HKD1_k127_2099408_2 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 398.0
HKD1_k127_2099408_3 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000001576 166.0
HKD1_k127_2099408_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000001295 130.0
HKD1_k127_2124539_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 314.0
HKD1_k127_2124539_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000001969 269.0
HKD1_k127_2124539_2 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.0001026 48.0
HKD1_k127_213830_0 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 451.0
HKD1_k127_213830_1 PFAM glycosyl transferase, family 28 K05841 - 2.4.1.173 0.000000000000000000000000003684 115.0
HKD1_k127_213830_2 - - - - 0.00000000008065 72.0
HKD1_k127_213830_3 Domain of unknown function (DUF4136) - - - 0.00001349 55.0
HKD1_k127_2146525_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000008499 148.0
HKD1_k127_2146525_1 Pathogenicity locus - - - 0.00000000000000000000008836 101.0
HKD1_k127_2146525_2 acetyltransferase - - - 0.00000000000000000004452 96.0
HKD1_k127_2146525_3 Transcriptional regulator PadR-like family - - - 0.000000004741 66.0
HKD1_k127_2147349_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 333.0
HKD1_k127_2147349_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000001248 61.0
HKD1_k127_2150313_0 Phosphate acetyl/butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 353.0
HKD1_k127_2150313_1 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000001422 218.0
HKD1_k127_2150313_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000002552 128.0
HKD1_k127_2151706_0 Amidase K01426 - 3.5.1.4 2.157e-235 740.0
HKD1_k127_2151706_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.908e-231 734.0
HKD1_k127_2172886_0 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.000000000000000000000000000000000000000000000000000000001194 227.0
HKD1_k127_2185326_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 311.0
HKD1_k127_2219403_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 321.0
HKD1_k127_2219403_1 PFAM extracellular solute-binding protein, family 5 K02035,K15580 - - 0.0000000000000000000000000009023 133.0
HKD1_k127_2219403_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000005959 121.0
HKD1_k127_2224244_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 366.0
HKD1_k127_2224244_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000008939 57.0
HKD1_k127_2225048_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1233.0
HKD1_k127_2225048_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000003504 85.0
HKD1_k127_2227307_0 surface antigen variable number - - - 0.000000000000000000000000000005898 136.0
HKD1_k127_2227307_1 protein secretion K09800 - - 0.000000000000000000007573 98.0
HKD1_k127_2239310_0 radical SAM domain protein - - - 3.928e-228 717.0
HKD1_k127_2239310_1 zinc metalloprotease K11749 - - 0.000000000000000000000573 101.0
HKD1_k127_2239771_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 371.0
HKD1_k127_2239771_1 O-Antigen ligase K02847 - - 0.00000000000000000000000000000000000000000000001675 188.0
HKD1_k127_2239771_2 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000159 148.0
HKD1_k127_2239771_3 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000003951 85.0
HKD1_k127_2239771_4 Sodium/hydrogen exchanger family K03316 - - 0.0000000000008957 71.0
HKD1_k127_2239771_5 PFAM lipopolysaccharide biosynthesis protein K16554,K16692 - - 0.0009651 49.0
HKD1_k127_2269804_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 571.0
HKD1_k127_2269804_1 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 395.0
HKD1_k127_2273471_0 Ribosomal protein S1 K02945 - - 1.134e-204 655.0
HKD1_k127_2273471_1 PFAM peptidase S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 264.0
HKD1_k127_2273471_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000001027 217.0
HKD1_k127_2273471_3 oxidoreductase activity K12511 - - 0.0000000000000000000000003521 117.0
HKD1_k127_227623_0 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000001152 213.0
HKD1_k127_227623_1 ribose 5-phosphate isomerase B K00761,K01808 - 2.4.2.9,5.3.1.6 0.000000000000000000000000000000000000000000009555 170.0
HKD1_k127_227623_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000004989 141.0
HKD1_k127_227623_3 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0003331 51.0
HKD1_k127_2289484_0 polysaccharide biosynthetic process K06409 - - 0.00000000000000000000000000000000000000000000000000000000000000001957 242.0
HKD1_k127_2289484_1 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000001152 198.0
HKD1_k127_2289484_2 glycosyl transferase group 1 - - - 0.00000000000000000004926 100.0
HKD1_k127_2308143_0 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 342.0
HKD1_k127_2308143_1 Metalloenzyme superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001309 228.0
HKD1_k127_2308143_2 Soluble NSF attachment protein, SNAP - - - 0.00000000000000000000000000000000000000006172 175.0
HKD1_k127_2308143_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000017 50.0
HKD1_k127_231571_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 304.0
HKD1_k127_2325000_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 438.0
HKD1_k127_2325000_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 416.0
HKD1_k127_2325000_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 366.0
HKD1_k127_2325000_3 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 368.0
HKD1_k127_2325000_4 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000002038 68.0
HKD1_k127_2329597_0 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
HKD1_k127_2329597_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000002834 113.0
HKD1_k127_2331208_0 Penicillin-binding Protein K05364 - - 0.00000000000000000000000000000000000000000000000003417 199.0
HKD1_k127_2331208_1 Inner membrane component of T3SS, cytoplasmic domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000000005236 68.0
HKD1_k127_2338421_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 508.0
HKD1_k127_2338421_1 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000000003111 205.0
HKD1_k127_2338421_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000005858 108.0
HKD1_k127_2340581_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 554.0
HKD1_k127_2340581_1 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 525.0
HKD1_k127_2340581_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 309.0
HKD1_k127_2340581_3 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000006609 195.0
HKD1_k127_2341644_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 383.0
HKD1_k127_2341644_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000001173 155.0
HKD1_k127_2341644_2 hydrolase activity, hydrolyzing N-glycosyl compounds - - - 0.000000000000000000000000000000001709 133.0
HKD1_k127_2341644_3 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000001179 89.0
HKD1_k127_2341644_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000001413 90.0
HKD1_k127_2354676_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000001522 237.0
HKD1_k127_2354676_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000002357 91.0
HKD1_k127_2354676_2 Tetratricopeptide repeats - - - 0.0000000000005105 82.0
HKD1_k127_2366376_0 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 297.0
HKD1_k127_2366376_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000006832 181.0
HKD1_k127_2366376_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000002433 190.0
HKD1_k127_2366376_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000001441 144.0
HKD1_k127_2366376_4 Hep Hag repeat protein K21449 - - 0.00000000000000000000000001296 113.0
HKD1_k127_2367097_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 9.898e-288 904.0
HKD1_k127_2401974_0 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.00000000000000000000000000000000000000000000000006259 193.0
HKD1_k127_2401974_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000007223 143.0
HKD1_k127_2402229_0 Secretion system protein K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 528.0
HKD1_k127_2402229_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 310.0
HKD1_k127_2402229_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
HKD1_k127_2402229_3 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000002387 246.0
HKD1_k127_2402229_4 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000009672 221.0
HKD1_k127_2402229_5 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000001096 214.0
HKD1_k127_2402229_6 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000001474 212.0
HKD1_k127_2402229_7 - - - - 0.00000000000000000000000000000000000000005225 160.0
HKD1_k127_2402229_8 - - - - 0.0007057 48.0
HKD1_k127_2411848_0 PFAM Helix-turn-helix, type 11 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 370.0
HKD1_k127_2411848_1 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 263.0
HKD1_k127_2411848_2 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000009346 151.0
HKD1_k127_2411848_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000008207 126.0
HKD1_k127_2411848_4 ribosomal large subunit export from nucleus - - - 0.000000000000000000000006655 110.0
HKD1_k127_2411848_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000004606 71.0
HKD1_k127_2411848_6 Family of unknown function (DUF5335) - - - 0.00000000007519 67.0
HKD1_k127_2411848_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000003614 63.0
HKD1_k127_2423437_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000323 251.0
HKD1_k127_2423437_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002098 257.0
HKD1_k127_2434399_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 460.0
HKD1_k127_2434399_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000551 247.0
HKD1_k127_2434399_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000001135 244.0
HKD1_k127_2434399_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000009621 246.0
HKD1_k127_2434399_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000009464 131.0
HKD1_k127_2434399_5 transmembrane transport K02035,K15580 - - 0.000000000000000000001291 111.0
HKD1_k127_2438097_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000002942 76.0
HKD1_k127_2438097_1 Polysaccharide biosynthesis protein - - - 0.00000008451 63.0
HKD1_k127_2445275_0 Aldo Keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 480.0
HKD1_k127_2445275_1 HEAT repeat - - - 0.0000000000000003543 85.0
HKD1_k127_2445275_2 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000004701 70.0
HKD1_k127_2445275_3 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.0001095 54.0
HKD1_k127_2445952_0 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 564.0
HKD1_k127_2449765_0 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000003363 251.0
HKD1_k127_2449765_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000003485 231.0
HKD1_k127_2449765_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000003414 143.0
HKD1_k127_24518_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 7.492e-311 975.0
HKD1_k127_24518_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 355.0
HKD1_k127_24518_2 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 314.0
HKD1_k127_24518_3 Belongs to the universal stress protein A family - - - 0.000000001559 64.0
HKD1_k127_2459784_0 protein trimerization - - - 0.00000003454 66.0
HKD1_k127_2466286_0 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 424.0
HKD1_k127_2466286_1 transglycosylase associated protein - - - 0.00000000000000000001124 94.0
HKD1_k127_2472223_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.623e-311 971.0
HKD1_k127_2472223_1 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000001241 214.0
HKD1_k127_2472223_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000000000008218 117.0
HKD1_k127_2472223_3 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.000000000000000000000005854 107.0
HKD1_k127_2472223_4 Outer membrane lipoprotein - - - 0.0000001381 63.0
HKD1_k127_2485300_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1755.0
HKD1_k127_2485300_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000005575 161.0
HKD1_k127_2485300_2 Evidence 4 Homologs of previously reported genes of K21440 - - 0.00000000000000000001379 98.0
HKD1_k127_2495558_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000293 211.0
HKD1_k127_2495558_1 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000002795 209.0
HKD1_k127_2495558_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000007078 173.0
HKD1_k127_2495558_3 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000009978 157.0
HKD1_k127_2504898_0 ADP-glyceromanno-heptose 6-epimerase activity K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 499.0
HKD1_k127_2504898_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 338.0
HKD1_k127_2504898_2 NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000003095 188.0
HKD1_k127_2504898_3 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.000000000001785 70.0
HKD1_k127_2504898_4 Glycosyl transferase 4-like - - - 0.00000000002648 70.0
HKD1_k127_2506744_0 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 385.0
HKD1_k127_2506744_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001007 202.0
HKD1_k127_2506744_2 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000009873 160.0
HKD1_k127_2506744_3 Parallel beta-helix repeats - - - 0.00000002909 63.0
HKD1_k127_2518982_0 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 365.0
HKD1_k127_2518982_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000001883 159.0
HKD1_k127_2519712_0 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 308.0
HKD1_k127_2519712_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001074 181.0
HKD1_k127_2519712_2 metallopeptidase activity - - - 0.0000000000000000000000000003498 124.0
HKD1_k127_2519712_3 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000001573 113.0
HKD1_k127_2529599_0 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 346.0
HKD1_k127_2529599_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005348 263.0
HKD1_k127_2539437_0 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 404.0
HKD1_k127_2539437_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 337.0
HKD1_k127_2539437_2 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000004777 222.0
HKD1_k127_2539437_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000009697 186.0
HKD1_k127_2540167_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 571.0
HKD1_k127_2540167_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 468.0
HKD1_k127_2540167_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000004483 269.0
HKD1_k127_2540167_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000004179 179.0
HKD1_k127_2540167_4 Chorismate mutase type II K03856,K04092,K04093,K04516,K13853 - 2.5.1.54,5.4.99.5 0.000000000000000000003164 98.0
HKD1_k127_2569695_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000115 221.0
HKD1_k127_2569695_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000001997 190.0
HKD1_k127_2569695_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000002018 175.0
HKD1_k127_2569695_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000005438 102.0
HKD1_k127_2569695_4 AntiSigma factor - GO:0005575,GO:0016020 - 0.0000004166 57.0
HKD1_k127_2594993_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 322.0
HKD1_k127_2594993_1 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000009132 154.0
HKD1_k127_2598173_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 332.0
HKD1_k127_2598173_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 316.0
HKD1_k127_2598173_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 305.0
HKD1_k127_2598173_3 Peptidase family M28 - - - 0.000000000001438 68.0
HKD1_k127_2602425_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 3.943e-282 885.0
HKD1_k127_2602425_1 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000005177 135.0
HKD1_k127_2602425_2 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.000000000000000000000004222 106.0
HKD1_k127_2609205_0 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 2.502e-242 768.0
HKD1_k127_2609205_1 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000006904 196.0
HKD1_k127_2624339_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 405.0
HKD1_k127_2624339_1 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000001689 116.0
HKD1_k127_2629843_0 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 465.0
HKD1_k127_2629843_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 351.0
HKD1_k127_2640448_0 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000006589 133.0
HKD1_k127_2640448_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000001579 104.0
HKD1_k127_2656634_0 metallocarboxypeptidase activity K14054 - - 0.0 1137.0
HKD1_k127_2663945_0 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000512 90.0
HKD1_k127_2663956_0 FtsX-like permease family - - - 7.824e-253 807.0
HKD1_k127_2673052_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 605.0
HKD1_k127_2673052_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 567.0
HKD1_k127_2673052_2 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000007762 190.0
HKD1_k127_2679843_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 589.0
HKD1_k127_2679843_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000004041 138.0
HKD1_k127_2679843_2 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000001618 115.0
HKD1_k127_2679843_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000007459 69.0
HKD1_k127_2692736_0 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 485.0
HKD1_k127_2692736_1 sugar phosphate isomerase involved in capsule formation K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000009276 221.0
HKD1_k127_2692736_2 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000003454 98.0
HKD1_k127_2712116_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 310.0
HKD1_k127_2712116_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 302.0
HKD1_k127_2712116_2 - - - - 0.0000000000000000000000000000000000000000000000001963 182.0
HKD1_k127_2712116_3 Cytochrome c - - - 0.000000000000000000000000000000486 124.0
HKD1_k127_2712116_4 TIGRFAM endoribonuclease L-PSP - - - 0.00000000000000000000000006265 108.0
HKD1_k127_271321_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 391.0
HKD1_k127_271321_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000008912 212.0
HKD1_k127_271321_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000001217 120.0
HKD1_k127_2738401_0 Peptidase S46 - - - 1.04e-228 729.0
HKD1_k127_2738401_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.054e-204 654.0
HKD1_k127_2738401_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000225 116.0
HKD1_k127_2738401_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000002137 105.0
HKD1_k127_2747152_0 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 6.652e-211 667.0
HKD1_k127_2747152_1 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001485 273.0
HKD1_k127_274729_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.481e-316 997.0
HKD1_k127_274729_1 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 477.0
HKD1_k127_274729_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 392.0
HKD1_k127_274729_3 protein histidine kinase activity K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 401.0
HKD1_k127_274729_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
HKD1_k127_274729_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000008298 87.0
HKD1_k127_2759810_0 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 416.0
HKD1_k127_2759810_1 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 390.0
HKD1_k127_2759810_2 Uncharacterized protein family (UPF0051) K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004467 267.0
HKD1_k127_2759810_3 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000002004 93.0
HKD1_k127_2780320_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 605.0
HKD1_k127_2780320_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 338.0
HKD1_k127_2780320_2 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000004384 53.0
HKD1_k127_2787127_0 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 431.0
HKD1_k127_2795593_0 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000003992 186.0
HKD1_k127_2816993_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007006 261.0
HKD1_k127_2816993_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000001591 235.0
HKD1_k127_2816993_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000006589 130.0
HKD1_k127_2816993_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000003709 111.0
HKD1_k127_2816993_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000001821 112.0
HKD1_k127_2816993_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000003429 78.0
HKD1_k127_2816993_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000001187 71.0
HKD1_k127_2819953_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 305.0
HKD1_k127_2819953_1 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000009281 248.0
HKD1_k127_2819953_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000002012 211.0
HKD1_k127_282150_0 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 355.0
HKD1_k127_282150_1 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000442 232.0
HKD1_k127_2832744_0 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 430.0
HKD1_k127_2833483_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 444.0
HKD1_k127_2833483_1 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000005427 118.0
HKD1_k127_2833483_2 PAS domain - - - 0.00002705 47.0
HKD1_k127_2837885_0 inositol monophosphate 1-phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 418.0
HKD1_k127_2837885_1 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 394.0
HKD1_k127_2837885_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 336.0
HKD1_k127_2843392_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.562e-197 637.0
HKD1_k127_2843392_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000001761 116.0
HKD1_k127_2843392_2 -O-antigen K02847 - - 0.0000000002594 73.0
HKD1_k127_2845902_0 exo-alpha-(2->6)-sialidase activity - - - 0.0005468 51.0
HKD1_k127_2870170_0 Belongs to the ClpA ClpB family K03696 - - 3.893e-294 915.0
HKD1_k127_2870170_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000001077 107.0
HKD1_k127_2877124_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000008194 157.0
HKD1_k127_2878150_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 417.0
HKD1_k127_2878150_1 - - - - 0.0000000001653 69.0
HKD1_k127_2879049_0 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000007592 86.0
HKD1_k127_2882002_0 FtsX-like permease family - - - 4.987e-200 656.0
HKD1_k127_2882002_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 324.0
HKD1_k127_2882002_2 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000001173 155.0
HKD1_k127_2882002_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000757 147.0
HKD1_k127_2893037_0 phosphoesterases, related to the Icc protein - - - 0.00000000000000000000000000000000000000000000000000000000000002863 220.0
HKD1_k127_2893037_1 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000003993 183.0
HKD1_k127_2893037_2 - - - - 0.0000000000006089 78.0
HKD1_k127_2893037_3 - - - - 0.0000000001942 68.0
HKD1_k127_2893037_4 - - - - 0.00000001312 61.0
HKD1_k127_2896579_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000009874 218.0
HKD1_k127_2896579_1 - - - - 0.000000000000000000000000000000000000000000000000000133 196.0
HKD1_k127_2896579_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000003266 162.0
HKD1_k127_2896579_3 Protein of unknown function (DUF3108) - - - 0.0000000000114 72.0
HKD1_k127_2935200_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 394.0
HKD1_k127_2935200_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006578 293.0
HKD1_k127_2935200_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005795 275.0
HKD1_k127_2935200_3 Major facilitator superfamily - - - 0.000000000000000000000000404 117.0
HKD1_k127_2949747_0 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 330.0
HKD1_k127_2949747_1 AMP binding - - - 0.000000000000000000000003841 113.0
HKD1_k127_2949747_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000000000000000002093 102.0
HKD1_k127_2949747_3 Universal stress protein family - - - 0.000000004702 67.0
HKD1_k127_2949747_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00007105 46.0
HKD1_k127_2959809_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002226 283.0
HKD1_k127_2959809_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000005335 123.0
HKD1_k127_2960339_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000002432 211.0
HKD1_k127_2985439_0 RNB K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 516.0
HKD1_k127_2987761_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006471 259.0
HKD1_k127_2987761_1 - - - - 0.000000000000000000000000000000000000000000000001503 179.0
HKD1_k127_2987761_2 Amino acid kinase family K00930 - 2.7.2.8 0.0000000000000000000000000001316 117.0
HKD1_k127_2993223_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 389.0
HKD1_k127_2993223_1 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 347.0
HKD1_k127_2993223_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000547 253.0
HKD1_k127_2993223_4 Ftsk_gamma K03466 - - 0.0000004346 54.0
HKD1_k127_2996234_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 400.0
HKD1_k127_2996234_1 Flavin reductase like domain - - - 0.0000000000000000000000003239 107.0
HKD1_k127_3000635_0 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 351.0
HKD1_k127_3000635_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 341.0
HKD1_k127_3000635_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 307.0
HKD1_k127_3000635_3 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000001634 199.0
HKD1_k127_3000635_4 NUDIX domain K03574 - 3.6.1.55 0.00000000000002188 75.0
HKD1_k127_300337_0 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000001537 250.0
HKD1_k127_300337_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000001348 184.0
HKD1_k127_300337_2 Integrin alpha (beta-propellor repeats). - - - 0.0002909 51.0
HKD1_k127_3006959_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 479.0
HKD1_k127_3006959_1 - - - - 0.0000000000000000000000000000000000000000000004819 173.0
HKD1_k127_3006959_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000001277 179.0
HKD1_k127_3006959_3 HEPN domain - - - 0.0000000000000000000537 93.0
HKD1_k127_3006959_4 nucleotidyltransferase activity K07076 - - 0.0000000000000005708 81.0
HKD1_k127_3006959_5 - - - - 0.0000000000006775 77.0
HKD1_k127_3019367_0 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 535.0
HKD1_k127_3019367_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 497.0
HKD1_k127_3033761_0 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 439.0
HKD1_k127_3033761_1 Pfam:Methyltransf_26 - - - 0.0000000000000000000000000000000000000000000000000005984 190.0
HKD1_k127_3035793_0 Tetratricopeptide repeats K12132 - 2.7.11.1 5.585e-200 649.0
HKD1_k127_3035793_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 530.0
HKD1_k127_3035793_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000005801 67.0
HKD1_k127_3035793_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000009988 59.0
HKD1_k127_3035793_4 Protein kinase domain K12132 - 2.7.11.1 0.0000003612 55.0
HKD1_k127_3043100_0 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 575.0
HKD1_k127_3043100_1 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 317.0
HKD1_k127_3043100_2 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000001101 227.0
HKD1_k127_3043100_3 Methenyl tetrahydrofolate cyclohydrolase - - - 0.000000000000000000000000000000000001382 148.0
HKD1_k127_3043100_4 Protein of unknown function (DUF971) - - - 0.000000000000000000003129 97.0
HKD1_k127_3043820_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 494.0
HKD1_k127_3043820_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 461.0
HKD1_k127_305117_0 choline dehydrogenase activity - - - 7.094e-234 735.0
HKD1_k127_305117_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 397.0
HKD1_k127_305117_2 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000000000005207 156.0
HKD1_k127_305117_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000001663 100.0
HKD1_k127_305117_4 PFAM Endoribonuclease L-PSP - - - 0.0000009533 56.0
HKD1_k127_3066583_0 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 290.0
HKD1_k127_3066583_1 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000581 270.0
HKD1_k127_3066583_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000003217 147.0
HKD1_k127_3066583_3 Transcriptional regulator - - - 0.000000000000000000000000000000001485 133.0
HKD1_k127_3066583_4 PFAM Sporulation and spore germination - - - 0.0001527 46.0
HKD1_k127_3070614_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
HKD1_k127_3070614_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001223 234.0
HKD1_k127_3070614_2 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000009303 195.0
HKD1_k127_3070614_3 alkylhydroperoxidase like protein, AhpD family - - - 0.000000003394 63.0
HKD1_k127_3072227_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 434.0
HKD1_k127_3077812_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 378.0
HKD1_k127_3077812_1 proteins of the AP superfamily K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 340.0
HKD1_k127_3077812_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000004098 230.0
HKD1_k127_3077812_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000002034 131.0
HKD1_k127_3077812_4 Domain of unknown function (DUF3488) - - - 0.00000000000000000004591 102.0
HKD1_k127_3089261_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 343.0
HKD1_k127_3117831_0 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000002181 153.0
HKD1_k127_3117831_1 lytic transglycosylase activity K03194 - - 0.000000000000000003399 96.0
HKD1_k127_3117831_2 - - - - 0.00000002482 62.0
HKD1_k127_3147403_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 501.0
HKD1_k127_3147403_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005534 285.0
HKD1_k127_3147403_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001317 248.0
HKD1_k127_3147403_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000002738 150.0
HKD1_k127_3147403_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000002066 82.0
HKD1_k127_3150895_0 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 296.0
HKD1_k127_3199067_0 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000004135 182.0
HKD1_k127_3199067_1 alpha beta - - - 0.00000000000000002239 95.0
HKD1_k127_3199067_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0001136 52.0
HKD1_k127_3199480_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003517 247.0
HKD1_k127_3199480_1 membrane - - - 0.0000000000000000000000000000000000000002299 154.0
HKD1_k127_3199480_2 - - - - 0.00000000000000000000000000004409 130.0
HKD1_k127_3199480_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000007909 69.0
HKD1_k127_3218048_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 605.0
HKD1_k127_3218048_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000008932 189.0
HKD1_k127_3218048_2 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000836 130.0
HKD1_k127_3218048_3 Domain of Unknown Function (DUF350) - - - 0.0000000000000009364 81.0
HKD1_k127_3218048_4 Domain of unknown function (DUF4178) - - - 0.000000000008768 68.0
HKD1_k127_3218303_0 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002447 261.0
HKD1_k127_3218303_1 hyperosmotic response - - - 0.000000000000000000000000000000006321 135.0
HKD1_k127_3218303_2 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000002002 117.0
HKD1_k127_3218303_3 - - - - 0.000000000000000000000009764 113.0
HKD1_k127_3234416_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 391.0
HKD1_k127_3234416_1 Major Facilitator Superfamily - - - 0.00006612 46.0
HKD1_k127_3244961_0 xylan catabolic process - - - 0.0000000000000000000000000000004147 128.0
HKD1_k127_3250997_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 552.0
HKD1_k127_3250997_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 316.0
HKD1_k127_3259145_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 581.0
HKD1_k127_3259145_1 Domain of unknown function (DUF3471) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 542.0
HKD1_k127_3259145_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000001769 247.0
HKD1_k127_3259145_3 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000002142 182.0
HKD1_k127_3259145_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000000005063 169.0
HKD1_k127_3259145_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000001316 106.0
HKD1_k127_3281964_0 OmpA family K02557,K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 389.0
HKD1_k127_3281964_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001249 168.0
HKD1_k127_3285165_0 class II (D K K01893 - 6.1.1.22 6.279e-195 616.0
HKD1_k127_3285165_1 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000006795 128.0
HKD1_k127_3289349_0 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 372.0
HKD1_k127_3289349_1 cytochrome - - - 0.0000000000000000000000000000000000000000001275 168.0
HKD1_k127_3289349_2 MerR, DNA binding - - - 0.0000000000000000000000000000000000000000006015 162.0
HKD1_k127_3294490_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 371.0
HKD1_k127_3294490_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000002713 201.0
HKD1_k127_3294490_2 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000003097 168.0
HKD1_k127_3294490_3 Protein of unknown function DUF84 - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.0000000000000000000000000000938 123.0
HKD1_k127_3294490_4 DinB family - - - 0.000000000003091 73.0
HKD1_k127_3294490_5 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0004594 51.0
HKD1_k127_3302021_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 429.0
HKD1_k127_3302021_1 Protein involved in hydrolase activity K06889 - - 0.00000000000000000000000000000000001867 149.0
HKD1_k127_3302021_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000003223 131.0
HKD1_k127_3337868_0 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 294.0
HKD1_k127_3337868_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000004133 142.0
HKD1_k127_3340510_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 548.0
HKD1_k127_3340510_1 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 496.0
HKD1_k127_3340510_2 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 390.0
HKD1_k127_3340510_3 positive regulation of MDA-5 signaling pathway - - - 0.00000000000000006754 91.0
HKD1_k127_3341711_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 442.0
HKD1_k127_3341711_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 358.0
HKD1_k127_3341711_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 295.0
HKD1_k127_3341711_3 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000000004578 244.0
HKD1_k127_3341711_4 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000003765 222.0
HKD1_k127_3341711_5 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000008147 207.0
HKD1_k127_3341711_6 Small Multidrug Resistance protein K03297,K11741 - - 0.000000000000000000000000000000000000000004087 157.0
HKD1_k127_3341711_7 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000000000000000001896 158.0
HKD1_k127_3341711_8 Pyridoxamine 5'-phosphate oxidase - - - 0.000182 49.0
HKD1_k127_3349250_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 333.0
HKD1_k127_3349250_1 Caulimovirus viroplasmin K06993 - - 0.000000000000000000000000000000000000000000000000000000000000000003342 241.0
HKD1_k127_3349250_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000006162 85.0
HKD1_k127_3372209_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 380.0
HKD1_k127_3372209_1 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 326.0
HKD1_k127_3372209_2 oxidoreductase activity - - - 0.000000000000000000000000000000002689 149.0
HKD1_k127_3373700_0 SnoaL-like domain - - - 0.0003843 49.0
HKD1_k127_3374997_0 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 581.0
HKD1_k127_3374997_1 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000005809 210.0
HKD1_k127_3374997_2 OmpA family - - - 0.000000000000008372 81.0
HKD1_k127_3377876_0 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000006783 176.0
HKD1_k127_3377876_1 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000001386 130.0
HKD1_k127_3377876_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000002817 55.0
HKD1_k127_338650_0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000002681 171.0
HKD1_k127_338650_1 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000001809 168.0
HKD1_k127_338650_2 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006045 94.0
HKD1_k127_338650_3 Ribosomal L29 protein K02904 - - 0.00000000001283 68.0
HKD1_k127_3411729_0 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 584.0
HKD1_k127_3411729_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 359.0
HKD1_k127_3411729_2 Predicted membrane protein (DUF2238) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 335.0
HKD1_k127_3411729_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 316.0
HKD1_k127_3411729_4 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003175 266.0
HKD1_k127_3411729_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000013 158.0
HKD1_k127_3411729_6 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000007729 103.0
HKD1_k127_3411729_7 HemY domain protein - - - 0.0000000000000005244 81.0
HKD1_k127_3411729_8 Protein of unknown function DUF58 - - - 0.0000000000002325 72.0
HKD1_k127_341383_1 - - - - 0.000000000000000000000000000002702 123.0
HKD1_k127_341383_2 - - - - 0.00000000000000000000000002129 110.0
HKD1_k127_3415608_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000003803 200.0
HKD1_k127_3415608_1 oxidoreductase activity K12511 - - 0.000000000000000000000000000000000000000000000002494 188.0
HKD1_k127_3415608_2 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000001366 157.0
HKD1_k127_3415608_3 PFAM von Willebrand factor type A - - - 0.000000000000001068 83.0
HKD1_k127_3427394_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 610.0
HKD1_k127_3427394_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 452.0
HKD1_k127_3427394_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000002883 246.0
HKD1_k127_3427394_3 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000007887 199.0
HKD1_k127_3430925_0 membrane - - - 0.0000000000000001166 94.0
HKD1_k127_344185_0 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 1.46e-255 802.0
HKD1_k127_344185_1 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 7.014e-215 678.0
HKD1_k127_344185_2 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 361.0
HKD1_k127_344185_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 300.0
HKD1_k127_344185_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000002062 160.0
HKD1_k127_3442640_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005436 267.0
HKD1_k127_3442640_1 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000001933 211.0
HKD1_k127_3443505_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 535.0
HKD1_k127_3443505_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000005521 220.0
HKD1_k127_3455602_0 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001362 276.0
HKD1_k127_3455602_1 Belongs to the BshC family K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005285 254.0
HKD1_k127_3455602_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000001175 77.0
HKD1_k127_3455602_3 Multicopper oxidase K22348 - 1.16.3.3 0.00000006203 62.0
HKD1_k127_3459367_0 Class II Aldolase and Adducin N-terminal domain K00001,K01629 - 1.1.1.1,4.1.2.19 2.463e-317 985.0
HKD1_k127_3459367_1 isomerase K01820 - 5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 597.0
HKD1_k127_3459367_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 373.0
HKD1_k127_3459367_3 Alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 329.0
HKD1_k127_3459367_4 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001511 241.0
HKD1_k127_3459367_5 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.000000000000000000000000000000000000002166 149.0
HKD1_k127_3463717_0 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001084 278.0
HKD1_k127_3463717_1 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000002539 144.0
HKD1_k127_3475343_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 574.0
HKD1_k127_3475343_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 279.0
HKD1_k127_3475343_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003259 261.0
HKD1_k127_3475343_3 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007161 254.0
HKD1_k127_3480951_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 343.0
HKD1_k127_3480951_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000345 279.0
HKD1_k127_3480951_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000001719 224.0
HKD1_k127_3480951_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000014 116.0
HKD1_k127_3487054_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 458.0
HKD1_k127_3487054_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000006271 143.0
HKD1_k127_3487372_0 Probable molybdopterin binding domain K03742 - 3.5.1.42 0.000000000000000000000000000000000002091 142.0
HKD1_k127_3487372_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000005303 79.0
HKD1_k127_3487372_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001154 72.0
HKD1_k127_3510112_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 554.0
HKD1_k127_3510112_1 - K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 481.0
HKD1_k127_3510112_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 297.0
HKD1_k127_3522021_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 585.0
HKD1_k127_3522021_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 472.0
HKD1_k127_3522021_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 295.0
HKD1_k127_3522021_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009854 274.0
HKD1_k127_3536364_0 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 333.0
HKD1_k127_3536364_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 309.0
HKD1_k127_3536364_2 Peptidase, M16 K07263 - - 0.00000000000000000000000000001439 128.0
HKD1_k127_3550838_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 505.0
HKD1_k127_3582773_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1140.0
HKD1_k127_3582773_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000118 116.0
HKD1_k127_3586498_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 591.0
HKD1_k127_3586498_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 444.0
HKD1_k127_3586498_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 293.0
HKD1_k127_3586498_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000009083 238.0
HKD1_k127_3586498_4 outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000001302 145.0
HKD1_k127_3586498_5 nucleotide catabolic process - - - 0.00000000000000000000000000000002307 141.0
HKD1_k127_3586498_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000001086 74.0
HKD1_k127_3586498_7 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000009965 56.0
HKD1_k127_3595348_0 cellulose binding - - - 0.0 1015.0
HKD1_k127_3595348_1 - - - - 0.00000000000000000000000000000000000000000000000000002034 196.0
HKD1_k127_3595348_2 - - - - 0.000000000000000000000000001513 117.0
HKD1_k127_3595348_3 oligosaccharyl transferase activity - - - 0.0005723 46.0
HKD1_k127_3603529_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 509.0
HKD1_k127_361137_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000001769 160.0
HKD1_k127_361137_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000001504 138.0
HKD1_k127_361137_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00001823 57.0
HKD1_k127_3617506_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.477e-218 688.0
HKD1_k127_3617506_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 348.0
HKD1_k127_3617506_2 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000000000000000005407 190.0
HKD1_k127_3617506_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000074 155.0
HKD1_k127_3617506_4 Hypothetical methyltransferase - - - 0.000000000000000000000000000000275 132.0
HKD1_k127_3620332_0 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000001976 144.0
HKD1_k127_3620332_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000001131 134.0
HKD1_k127_3621422_0 Cupin - - - 0.00000000000000000004024 97.0
HKD1_k127_3621422_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000008303 78.0
HKD1_k127_3625586_0 Prolyl oligopeptidase family - - - 3.173e-247 782.0
HKD1_k127_3625586_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000001655 111.0
HKD1_k127_3625586_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000001813 111.0
HKD1_k127_3625802_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 577.0
HKD1_k127_3625802_1 - - - - 0.000007447 57.0
HKD1_k127_3674795_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 460.0
HKD1_k127_3674795_1 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 398.0
HKD1_k127_3674795_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000001221 181.0
HKD1_k127_3674795_3 Domain of unknown function (DUF4159) - - - 0.0004482 48.0
HKD1_k127_3678728_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.408e-223 711.0
HKD1_k127_3688120_0 iron ion homeostasis - - - 0.00000000000000000000000000000000000008746 160.0
HKD1_k127_3688120_1 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000009537 134.0
HKD1_k127_3688120_2 von Willebrand factor, type A - - - 0.000000000000000000008024 105.0
HKD1_k127_3688120_3 Domain of unknown function (DUF4870) - - - 0.0000003603 59.0
HKD1_k127_3692601_0 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 422.0
HKD1_k127_3692601_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 310.0
HKD1_k127_3696338_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 459.0
HKD1_k127_3696338_1 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 308.0
HKD1_k127_3696338_2 - - - - 0.000000000000000000000000000000000000000000000000001602 189.0
HKD1_k127_3696338_3 Protein of unknown function (DUF4242) - - - 0.000000000000000001188 88.0
HKD1_k127_3701696_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 442.0
HKD1_k127_3701696_1 - - - - 0.00000000000000000000000000000000000000000000000000000001463 208.0
HKD1_k127_3701696_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000004197 118.0
HKD1_k127_3705256_0 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 516.0
HKD1_k127_3705256_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 330.0
HKD1_k127_3705256_2 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002507 279.0
HKD1_k127_3705256_3 Protein of unknown function (DUF3311) - - - 0.00000000001273 70.0
HKD1_k127_3737251_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K00982,K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016020,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15,2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000002255 198.0
HKD1_k127_3737251_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000004192 197.0
HKD1_k127_3746756_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000005673 81.0
HKD1_k127_3746756_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000001713 60.0
HKD1_k127_3746756_2 sigma54 specific, transcriptional regulator, Fis family - - - 0.00003723 56.0
HKD1_k127_3763881_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 449.0
HKD1_k127_3763881_1 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000000000000000000000000000000000000853 179.0
HKD1_k127_3764119_0 Alkaline phosphatase K01113 - 3.1.3.1 1.599e-198 634.0
HKD1_k127_3764119_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 506.0
HKD1_k127_3765858_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001709 302.0
HKD1_k127_3767542_0 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000001326 205.0
HKD1_k127_3767542_1 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000003734 64.0
HKD1_k127_3767542_2 energy transducer activity K02487,K03832,K06596 - - 0.0000002027 63.0
HKD1_k127_3786288_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000001505 167.0
HKD1_k127_3786288_1 BlaR1 peptidase M56 - - - 0.00000000002229 73.0
HKD1_k127_3794642_0 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 1.651e-224 706.0
HKD1_k127_3794642_1 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 394.0
HKD1_k127_3794642_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000001283 174.0
HKD1_k127_3800366_0 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000354 204.0
HKD1_k127_3800366_1 photosynthesis - - - 0.0000000000000000000000000000000000000000000003007 169.0
HKD1_k127_3800366_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000002351 169.0
HKD1_k127_3800366_3 PFAM peptidase K01438 - 3.5.1.16 0.00000000000000000000000004675 110.0
HKD1_k127_3802192_0 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 348.0
HKD1_k127_3802192_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 343.0
HKD1_k127_3802192_2 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 303.0
HKD1_k127_3802192_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000007218 203.0
HKD1_k127_3802192_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000006633 173.0
HKD1_k127_3802192_5 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000006103 159.0
HKD1_k127_3802192_6 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000003082 154.0
HKD1_k127_3806197_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 426.0
HKD1_k127_3806197_1 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 292.0
HKD1_k127_3806197_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000005794 156.0
HKD1_k127_3806197_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000464 137.0
HKD1_k127_3806197_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000001836 135.0
HKD1_k127_3806197_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001333 131.0
HKD1_k127_3806197_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000002447 126.0
HKD1_k127_3806197_7 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000001134 122.0
HKD1_k127_3808795_0 PFAM YdjC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000002047 222.0
HKD1_k127_3815991_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 590.0
HKD1_k127_3815991_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000001975 227.0
HKD1_k127_3815991_2 response regulator K02282,K07705 - - 0.000000000000000000000000000005335 123.0
HKD1_k127_3815991_3 YceI-like domain - - - 0.0000000000000000000000003245 112.0
HKD1_k127_3821308_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 581.0
HKD1_k127_3821308_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000005851 150.0
HKD1_k127_3821308_2 GDP-mannose mannosyl hydrolase activity K00974,K03574,K18445 - 2.7.7.72,3.6.1.55,3.6.1.61 0.000000000000000000000000001519 118.0
HKD1_k127_3830547_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 1.829e-315 978.0
HKD1_k127_3830547_1 DEAD DEAH box helicase K03724 - - 0.000000000007473 67.0
HKD1_k127_3833320_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.903e-276 871.0
HKD1_k127_3833320_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 325.0
HKD1_k127_3833320_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 291.0
HKD1_k127_3833320_3 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 293.0
HKD1_k127_3833320_4 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000001956 226.0
HKD1_k127_3833320_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000476 102.0
HKD1_k127_3837448_0 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 451.0
HKD1_k127_3837448_1 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 375.0
HKD1_k127_3837448_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001733 237.0
HKD1_k127_3837448_3 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.00000000000000000000000000000000000000000002618 170.0
HKD1_k127_3837448_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000006917 102.0
HKD1_k127_3837448_5 PFAM YkuD domain K16291 - - 0.00000000000000005011 94.0
HKD1_k127_3868660_0 activity. It is involved in the biological process described with metabolic process K00615 GO:0000287,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005777,GO:0005783,GO:0005789,GO:0005829,GO:0005975,GO:0005996,GO:0005997,GO:0005999,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009058,GO:0009117,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0012505,GO:0016020,GO:0016051,GO:0016604,GO:0016607,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019321,GO:0019322,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030246,GO:0030976,GO:0031323,GO:0031326,GO:0031935,GO:0031974,GO:0031981,GO:0031984,GO:0033043,GO:0033044,GO:0034641,GO:0036094,GO:0040008,GO:0042175,GO:0042579,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046166,GO:0046184,GO:0046364,GO:0046390,GO:0046483,GO:0046496,GO:0046872,GO:0046983,GO:0048029,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051128,GO:0051156,GO:0051171,GO:0051186,GO:0051252,GO:0055086,GO:0060255,GO:0060968,GO:0065007,GO:0070013,GO:0071704,GO:0072524,GO:0080090,GO:0090407,GO:0097159,GO:0098827,GO:1901135,GO:1901137,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681,GO:1902275,GO:1903506,GO:2000112,GO:2001141 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002899 245.0
HKD1_k127_3868660_1 PFAM Cupin domain - - - 0.0000000000000000000000000000000000000000000000000265 181.0
HKD1_k127_3868660_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000308 59.0
HKD1_k127_3868660_3 Bacterial transcriptional activator domain - - - 0.000006316 59.0
HKD1_k127_3869151_0 PFAM NAD-dependent epimerase dehydratase - - - 1.338e-195 621.0
HKD1_k127_3869151_1 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000000000000000001913 187.0
HKD1_k127_3869151_2 PFAM Fasciclin domain - - - 0.0000000000000000000000000000000000000000000000001478 180.0
HKD1_k127_3869151_3 TspO/MBR family - - - 0.0000000000000000000000000000000000000000001343 168.0
HKD1_k127_3869151_4 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000004632 147.0
HKD1_k127_3869151_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000003113 135.0
HKD1_k127_387885_0 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000006186 245.0
HKD1_k127_387885_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000002402 205.0
HKD1_k127_387885_2 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000003762 185.0
HKD1_k127_387885_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000008002 175.0
HKD1_k127_389322_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000003353 227.0
HKD1_k127_389322_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000002041 180.0
HKD1_k127_389322_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000004217 171.0
HKD1_k127_389322_3 Transcriptional regulator, LysR family - - - 0.000000000002389 73.0
HKD1_k127_390147_0 amidohydrolase K07045 - - 0.000000000000000000000000000000000003312 152.0
HKD1_k127_390147_1 - - - - 0.000000000000000000000000000000002725 139.0
HKD1_k127_390147_2 Peptidase family M28 - - - 0.0001373 54.0
HKD1_k127_3902603_0 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 354.0
HKD1_k127_3902603_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 354.0
HKD1_k127_3902603_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000006681 196.0
HKD1_k127_3902603_3 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.00000000000000000000000000000000000001015 157.0
HKD1_k127_3902603_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000002969 130.0
HKD1_k127_3902603_6 Two component signalling adaptor domain K03408 - - 0.0002366 51.0
HKD1_k127_3911590_0 surface antigen variable number - - - 0.00000000000000001001 90.0
HKD1_k127_3911590_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000000003075 71.0
HKD1_k127_3916774_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000001907 143.0
HKD1_k127_3921395_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.438e-274 874.0
HKD1_k127_3921395_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 434.0
HKD1_k127_3921395_2 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 337.0
HKD1_k127_3921395_3 - - - - 0.00000000000000000000000000000000000000000000000000000000006634 219.0
HKD1_k127_3921395_4 Penicillinase repressor - - - 0.0000000000000000000000000000000000000001309 154.0
HKD1_k127_3921395_5 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000001264 162.0
HKD1_k127_3921395_6 PPIC-type PPIASE domain K03769,K03770,K03771,K07533 - 5.2.1.8 0.000000000009322 76.0
HKD1_k127_392623_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 355.0
HKD1_k127_392623_1 Mechanosensitive ion channel K05802,K22051 - - 0.0000000000000000000000000000000000000000000000000000000000005304 221.0
HKD1_k127_392623_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000001158 160.0
HKD1_k127_392623_3 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000001586 130.0
HKD1_k127_392623_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000002047 56.0
HKD1_k127_3929016_0 serine-type peptidase activity K01278 - 3.4.14.5 2.594e-321 997.0
HKD1_k127_3929016_1 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 383.0
HKD1_k127_3929016_2 Glutathione peroxidase K02199 - - 0.0000000000000000000000009884 112.0
HKD1_k127_3929016_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000006417 81.0
HKD1_k127_3929016_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000002577 88.0
HKD1_k127_393213_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 437.0
HKD1_k127_393213_1 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 364.0
HKD1_k127_393213_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 268.0
HKD1_k127_393213_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003854 241.0
HKD1_k127_393213_4 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000003592 205.0
HKD1_k127_393213_5 oxidoreductase activity - - - 0.00000000000000000000000000001011 136.0
HKD1_k127_393213_6 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000007136 80.0
HKD1_k127_3933075_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 351.0
HKD1_k127_3933075_1 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000000000007907 199.0
HKD1_k127_3933075_2 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000000000000000000000000000000000004198 151.0
HKD1_k127_3934179_0 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 271.0
HKD1_k127_3934179_1 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
HKD1_k127_3936250_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 562.0
HKD1_k127_3936250_1 - - - - 0.0000000000000174 84.0
HKD1_k127_3936250_2 - - - - 0.00000000005006 73.0
HKD1_k127_394980_0 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009126 272.0
HKD1_k127_394980_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000001885 194.0
HKD1_k127_3949897_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000009448 205.0
HKD1_k127_3949897_1 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 0.0000000000000000000000000000000000000000002468 162.0
HKD1_k127_3949897_2 RDD family - - - 0.00000000000000000000000000000000000000002915 162.0
HKD1_k127_3949897_3 positive regulation of translation, ncRNA-mediated K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.00000000000000000000000604 105.0
HKD1_k127_3963037_0 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 289.0
HKD1_k127_3963037_1 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
HKD1_k127_3963037_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000004544 140.0
HKD1_k127_3972238_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 315.0
HKD1_k127_3972238_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000009777 273.0
HKD1_k127_3976969_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1505.0
HKD1_k127_3976969_1 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 8.279e-234 731.0
HKD1_k127_3976969_2 Oxidoreductase K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 319.0
HKD1_k127_3976969_3 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000004865 216.0
HKD1_k127_3976969_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000005314 199.0
HKD1_k127_3976969_5 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000347 179.0
HKD1_k127_3976969_6 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000426 100.0
HKD1_k127_3977776_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 380.0
HKD1_k127_3977901_0 argininosuccinate lyase K01755,K14681 - 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 480.0
HKD1_k127_3977901_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000004123 115.0
HKD1_k127_3977901_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.00000000000000000000001408 101.0
HKD1_k127_3977901_3 PD-(D/E)XK nuclease superfamily - - - 0.000000001595 63.0
HKD1_k127_3985913_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 568.0
HKD1_k127_3985913_1 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 385.0
HKD1_k127_3985913_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 334.0
HKD1_k127_3985913_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000009047 229.0
HKD1_k127_3985913_4 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000002483 225.0
HKD1_k127_3985913_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000001128 185.0
HKD1_k127_3985913_6 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000001593 160.0
HKD1_k127_3985913_7 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000002914 134.0
HKD1_k127_3985913_8 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000001109 113.0
HKD1_k127_3996390_1 Possible lysine decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 297.0
HKD1_k127_3996390_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 298.0
HKD1_k127_3996390_3 CHAD - - - 0.0000000000000000000000000000000000000000000000004001 188.0
HKD1_k127_3996390_4 Ion channel - - - 0.0000000000000000000000000000001959 132.0
HKD1_k127_3996390_5 Beta-Casp domain K07576 - - 0.000000000000000000000000000001591 122.0
HKD1_k127_4016310_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.556e-273 854.0
HKD1_k127_4016310_1 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 299.0
HKD1_k127_4029508_0 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000008521 179.0
HKD1_k127_4029508_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000004563 160.0
HKD1_k127_4032939_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000003701 183.0
HKD1_k127_4032939_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000001811 138.0
HKD1_k127_4032939_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000007749 64.0
HKD1_k127_4033636_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 353.0
HKD1_k127_4033636_1 ATPases associated with a variety of cellular activities K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 327.0
HKD1_k127_4033636_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 293.0
HKD1_k127_4033636_3 - - - - 0.0000000000001226 74.0
HKD1_k127_4035746_0 SLBB domain K01991 - - 0.000000000000000000000000000001815 134.0
HKD1_k127_4035746_1 extracellular polysaccharide biosynthetic process K08252,K13661,K16554 - 2.7.10.1 0.000184 51.0
HKD1_k127_4038565_0 lysine biosynthesis protein LysW K05826 - - 0.000000003272 62.0
HKD1_k127_4054466_0 Forkhead associated domain - - - 0.000000000000000000000000000000006319 145.0
HKD1_k127_4061754_0 ABC transporter K06020 - 3.6.3.25 2.347e-303 936.0
HKD1_k127_4061754_1 (ABC) transporter K06147,K06148 - - 6.485e-212 679.0
HKD1_k127_4061754_2 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 427.0
HKD1_k127_4061754_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 415.0
HKD1_k127_4061754_4 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000008928 218.0
HKD1_k127_4071647_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000009304 177.0
HKD1_k127_4071647_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000002012 185.0
HKD1_k127_4071647_2 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000004502 150.0
HKD1_k127_4071647_3 'Cold-shock' DNA-binding domain K03704 - - 0.00001681 48.0
HKD1_k127_4086448_0 Elongation factor G, domain IV K02355 - - 7.208e-228 722.0
HKD1_k127_4086448_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 285.0
HKD1_k127_4086448_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
HKD1_k127_4086448_3 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000002666 141.0
HKD1_k127_4086448_4 Domain of unknown function (DUF4129) - - - 0.00000000002295 75.0
HKD1_k127_4086448_5 pathogenesis - - - 0.00002168 54.0
HKD1_k127_4094191_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 4.222e-202 641.0
HKD1_k127_4094191_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 488.0
HKD1_k127_4094191_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000003843 234.0
HKD1_k127_4094191_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000853 185.0
HKD1_k127_4095931_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 358.0
HKD1_k127_4095931_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000224 266.0
HKD1_k127_4099727_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000002501 232.0
HKD1_k127_4100640_0 Zinc carboxypeptidase - - - 3.93e-235 752.0
HKD1_k127_4100640_1 aminopeptidase - - - 6.999e-213 675.0
HKD1_k127_4100640_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 580.0
HKD1_k127_4100640_3 succinyl-diaminopimelate desuccinylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 512.0
HKD1_k127_4100640_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 476.0
HKD1_k127_4100640_5 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 341.0
HKD1_k127_4100640_6 RNA-binding protein - - - 0.0000000000000000000000000006349 116.0
HKD1_k127_4100640_7 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000005839 109.0
HKD1_k127_4100640_8 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000006773 87.0
HKD1_k127_4100867_0 Beta-lactamase K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 342.0
HKD1_k127_4100867_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003231 258.0
HKD1_k127_4100867_2 Protein of unknown function (DUF983) - - - 0.0000000000000000005727 94.0
HKD1_k127_4103365_0 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 287.0
HKD1_k127_4103365_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007031 269.0
HKD1_k127_4115911_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 501.0
HKD1_k127_4115911_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000002646 91.0
HKD1_k127_4115911_2 - - - - 0.00000001873 58.0
HKD1_k127_4137835_0 Peptidase family M1 domain - - - 1.36e-229 723.0
HKD1_k127_4137835_1 serine threonine protein kinase K12132 - 2.7.11.1 6.728e-227 734.0
HKD1_k127_4137835_2 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 330.0
HKD1_k127_4137835_3 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 304.0
HKD1_k127_4137835_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000003112 233.0
HKD1_k127_4137835_5 Encoded by - - - 0.0000000000000000000000000000000000000000000000006254 191.0
HKD1_k127_4137835_6 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000004082 136.0
HKD1_k127_4138936_0 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000001429 194.0
HKD1_k127_4138936_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000006297 181.0
HKD1_k127_4142720_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001601 290.0
HKD1_k127_4142720_1 - - - - 0.00000000000000000000000000000000000381 146.0
HKD1_k127_4142720_2 PFAM regulatory protein, MerR K13640 - - 0.0000000000000000000000000000000001308 136.0
HKD1_k127_4142720_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000001197 55.0
HKD1_k127_4142720_4 proteolysis K07059 - - 0.0000002782 62.0
HKD1_k127_4143741_0 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 596.0
HKD1_k127_4143741_1 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 340.0
HKD1_k127_4143741_2 Tyrosine phosphatase family - - - 0.00000000000000000000000001957 116.0
HKD1_k127_4152320_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 322.0
HKD1_k127_4152320_1 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007533 276.0
HKD1_k127_4152320_2 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000003581 93.0
HKD1_k127_4163545_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 299.0
HKD1_k127_4163545_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000005137 138.0
HKD1_k127_4197255_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.617e-211 676.0
HKD1_k127_4197255_1 Universal bacterial protein YeaZ K14742 - - 0.00000000000000006777 90.0
HKD1_k127_4200406_0 Tricorn protease C1 domain K08676 - - 0.0 1255.0
HKD1_k127_4200406_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000009549 181.0
HKD1_k127_4200406_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000000000000000000000000007569 123.0
HKD1_k127_4203624_0 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000004948 168.0
HKD1_k127_4203624_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000004592 155.0
HKD1_k127_4207442_0 DNA polymerase Ligase (LigD) - - - 6.493e-300 938.0
HKD1_k127_4207442_1 Dna alkylation repair - - - 0.00000000000000000000000000004852 119.0
HKD1_k127_4207442_2 - - - - 0.00000000000000000000000000009347 121.0
HKD1_k127_4211933_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000005146 78.0
HKD1_k127_4211933_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.0009201 45.0
HKD1_k127_4212648_0 Uncharacterized conserved protein (DUF2075) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 295.0
HKD1_k127_4212648_1 Protein of unknown function (DUF1294) - - - 0.000000000000000003681 85.0
HKD1_k127_4219722_0 PFAM peptidase - - - 1.881e-218 693.0
HKD1_k127_4219722_1 Domain of unknown function (DUF1990) - - - 0.000000000000000000000000000000000000000000000000001123 189.0
HKD1_k127_4219722_2 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.0000000000000000000000000000000000000004996 162.0
HKD1_k127_4221937_0 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000174 277.0
HKD1_k127_4221937_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000004261 248.0
HKD1_k127_4221937_2 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000007301 164.0
HKD1_k127_4221937_3 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.000000000000000000000000000000000000000001094 160.0
HKD1_k127_422682_0 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001568 228.0
HKD1_k127_422682_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000007227 190.0
HKD1_k127_4240099_0 serine-type peptidase activity - - - 0.0 1117.0
HKD1_k127_4241597_0 response to abiotic stimulus - - - 2.458e-257 807.0
HKD1_k127_4241597_1 response to abiotic stimulus K03086 - - 0.0001758 50.0
HKD1_k127_4245075_0 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 422.0
HKD1_k127_4245075_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001222 293.0
HKD1_k127_4245075_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000004592 198.0
HKD1_k127_4245075_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000006217 173.0
HKD1_k127_4245075_4 Alpha beta K06889 - - 0.000000000000000000000000000001623 132.0
HKD1_k127_4245075_5 TPR repeat-containing thioredoxin - GO:0001101,GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009787,GO:0009789,GO:0009966,GO:0009967,GO:0010033,GO:0010646,GO:0010647,GO:0023051,GO:0023056,GO:0033993,GO:0042221,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0097305,GO:1901419,GO:1901421,GO:1901700,GO:1905957,GO:1905959 - 0.00000002412 66.0
HKD1_k127_4249909_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 449.0
HKD1_k127_4249909_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 346.0
HKD1_k127_4249909_2 - - - - 0.00000000000002868 83.0
HKD1_k127_4249909_3 - - - - 0.000000000003144 78.0
HKD1_k127_4249909_4 Protein of unknown function (DUF3341) - - - 0.00005108 51.0
HKD1_k127_4254674_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 614.0
HKD1_k127_4254674_1 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 340.0
HKD1_k127_4254674_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009177 286.0
HKD1_k127_4254674_3 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000479 284.0
HKD1_k127_4254674_4 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.00000000000000000000000000000000000000000000000000000000000000002843 238.0
HKD1_k127_4254674_6 PFAM Abortive infection protein K07052 - - 0.00000000000000000002667 100.0
HKD1_k127_4254838_0 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 490.0
HKD1_k127_4254838_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 321.0
HKD1_k127_4254838_2 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000206 279.0
HKD1_k127_4254838_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000004674 248.0
HKD1_k127_4254838_4 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000008861 247.0
HKD1_k127_4254838_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000172 244.0
HKD1_k127_4254838_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000001053 234.0
HKD1_k127_4254838_7 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000000663 203.0
HKD1_k127_4262800_0 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000001878 221.0
HKD1_k127_4262800_1 Putative peptidoglycan binding domain - - - 0.0000001505 64.0
HKD1_k127_4270207_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.511e-270 860.0
HKD1_k127_4270207_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 518.0
HKD1_k127_4270207_2 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 396.0
HKD1_k127_4270207_3 Cupredoxin-like domain - - - 0.000000000000000000000000000000000000002166 149.0
HKD1_k127_4270207_4 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000005017 145.0
HKD1_k127_4270207_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000005937 114.0
HKD1_k127_4306282_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000003037 224.0
HKD1_k127_4322116_0 Tricorn protease C1 domain K08676 - - 7.714e-198 628.0
HKD1_k127_4322116_1 COG1228 Imidazolonepropionase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000007467 229.0
HKD1_k127_4322116_2 - - - - 0.0000000000000000000000000000000000000000001208 162.0
HKD1_k127_4333102_0 FtsX-like permease family - - - 3.116e-213 695.0
HKD1_k127_4333102_1 Peptidase family S41 - - - 0.00000003319 61.0
HKD1_k127_4333102_2 Peptidase family S41 - - - 0.0002844 47.0
HKD1_k127_436509_0 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 295.0
HKD1_k127_436509_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000003499 186.0
HKD1_k127_436509_2 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000402 139.0
HKD1_k127_436509_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000003987 88.0
HKD1_k127_4390580_0 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000008605 244.0
HKD1_k127_4404962_0 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 376.0
HKD1_k127_4404962_1 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 322.0
HKD1_k127_4404962_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000035 143.0
HKD1_k127_4407113_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 514.0
HKD1_k127_4407113_1 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000006335 66.0
HKD1_k127_442755_0 Putative adhesin - - - 0.000000172 63.0
HKD1_k127_4437877_0 - - - - 0.000000000000000000000000000000000000000000000000002712 197.0
HKD1_k127_4437877_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000006504 51.0
HKD1_k127_4451715_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 491.0
HKD1_k127_4451715_1 Major facilitator superfamily K08191 - - 0.000000000000000000000000000001571 123.0
HKD1_k127_4459773_0 histone H2A K63-linked ubiquitination K03220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 497.0
HKD1_k127_4459773_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 322.0
HKD1_k127_4459773_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 278.0
HKD1_k127_4459773_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007179 285.0
HKD1_k127_4459773_4 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002553 198.0
HKD1_k127_4460354_0 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000183 162.0
HKD1_k127_4460354_1 two-component system sensor-response regulator hybrid protein - - - 0.0000000006864 68.0
HKD1_k127_4465764_0 cell shape determining protein, MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000004966 222.0
HKD1_k127_4465764_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.000000000000000000005698 102.0
HKD1_k127_4503677_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 617.0
HKD1_k127_4503677_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005461 307.0
HKD1_k127_4503677_2 COG3209 Rhs family protein - - - 0.000000000005742 75.0
HKD1_k127_4506234_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000005343 76.0
HKD1_k127_452579_0 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 402.0
HKD1_k127_452579_1 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 311.0
HKD1_k127_452579_2 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 243.0
HKD1_k127_452579_3 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000000000000000000001447 180.0
HKD1_k127_452579_4 - - - - 0.000000000000000000000006497 109.0
HKD1_k127_4527526_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.145e-218 695.0
HKD1_k127_4527526_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000001804 120.0
HKD1_k127_4530664_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 345.0
HKD1_k127_4530664_1 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002795 268.0
HKD1_k127_4530664_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001722 251.0
HKD1_k127_4530664_3 Dna alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000008633 226.0
HKD1_k127_4530664_4 EVE domain - - - 0.000000000000000000000000000000000000000000000000007174 184.0
HKD1_k127_4530664_5 DinB family - - - 0.0000000000000000000000000000000000000000000005597 170.0
HKD1_k127_4530664_6 - - - - 0.0000000000000000000000002026 112.0
HKD1_k127_4545570_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000001485 217.0
HKD1_k127_4545570_1 Nitroreductase family - - - 0.00000000000000000000000001551 110.0
HKD1_k127_4552456_0 COGs COG1432 conserved - - - 0.000000000000000000000000000000000000000000000000000000000005308 214.0
HKD1_k127_4552456_1 Tetratricopeptide repeat - - - 0.000000003447 65.0
HKD1_k127_4552456_2 - - - - 0.00014 47.0
HKD1_k127_4567855_0 Carbon starvation protein K06200 - - 2.132e-217 694.0
HKD1_k127_4567855_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 373.0
HKD1_k127_4575576_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 2.757e-200 641.0
HKD1_k127_4575576_1 Zn-dependent hydrolase, glyoxylase - - - 0.000000000000000000000000000000000000000000000001283 183.0
HKD1_k127_4585674_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.989e-320 996.0
HKD1_k127_4585674_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 3.304e-204 644.0
HKD1_k127_4585674_2 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 454.0
HKD1_k127_4585674_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000002101 211.0
HKD1_k127_4585674_4 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000001236 207.0
HKD1_k127_4585674_5 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000001113 145.0
HKD1_k127_4597393_0 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000001092 271.0
HKD1_k127_4597393_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000004897 254.0
HKD1_k127_4597393_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000002483 158.0
HKD1_k127_4597393_3 Domain of unknown function (DUF1844) - - - 0.0000000000009113 76.0
HKD1_k127_4610533_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 472.0
HKD1_k127_4610533_1 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000001618 124.0
HKD1_k127_4610533_2 YwiC-like protein - - - 0.0000000000000000001255 98.0
HKD1_k127_4611892_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 482.0
HKD1_k127_4611892_1 Domain of unknown function (DUF4922) - - - 0.000000000000000000000000002618 116.0
HKD1_k127_4611892_2 Protein of unknown function (DUF1460) - - - 0.0000000000000000000189 98.0
HKD1_k127_461716_0 HD domain - - - 0.0000000000000000000000005622 119.0
HKD1_k127_4621136_0 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000255 223.0
HKD1_k127_4621136_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000004172 168.0
HKD1_k127_4621136_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000004742 106.0
HKD1_k127_4632590_0 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
HKD1_k127_4632590_1 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000008311 236.0
HKD1_k127_4632590_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000006693 237.0
HKD1_k127_4632590_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000005747 166.0
HKD1_k127_4634741_0 - - - - 1.98e-213 689.0
HKD1_k127_4634741_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 428.0
HKD1_k127_4634741_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
HKD1_k127_4634741_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000002342 202.0
HKD1_k127_4634741_4 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000004447 173.0
HKD1_k127_4634741_5 - - - - 0.0000000000000000000000000000008066 128.0
HKD1_k127_4634741_6 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000001499 111.0
HKD1_k127_4634741_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000002905 78.0
HKD1_k127_4663743_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 360.0
HKD1_k127_4663743_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 348.0
HKD1_k127_4663743_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 317.0
HKD1_k127_467091_0 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000001088 83.0
HKD1_k127_467091_1 Fibronectin type 3 domain - - - 0.0000000000001053 79.0
HKD1_k127_4675228_0 - - - - 0.00000000000000000000000000000000000000000000000000000000005822 218.0
HKD1_k127_4675228_1 TFIIS helical bundle-like domain - - - 0.000000000004039 78.0
HKD1_k127_4679891_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 362.0
HKD1_k127_4679891_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006196 280.0
HKD1_k127_470486_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000002323 240.0
HKD1_k127_470486_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000007339 171.0
HKD1_k127_470486_2 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000004008 123.0
HKD1_k127_470486_3 - - - - 0.0000000000000003822 81.0
HKD1_k127_470486_4 nuclease activity K06218 - - 0.0000001897 53.0
HKD1_k127_470486_5 General secretion pathway protein G K02456 - - 0.0001564 51.0
HKD1_k127_4709614_0 PFAM Protein kinase domain K12132 - 2.7.11.1 3.073e-227 730.0
HKD1_k127_4711657_0 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 472.0
HKD1_k127_4711657_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 309.0
HKD1_k127_4730680_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 344.0
HKD1_k127_4730680_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 330.0
HKD1_k127_4730680_2 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 252.0
HKD1_k127_4730680_3 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.0000000000000000000000000000000000000001608 157.0
HKD1_k127_4730680_4 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000003023 123.0
HKD1_k127_4740634_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 550.0
HKD1_k127_4740634_1 Cytochrome c K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 436.0
HKD1_k127_4740634_2 Domain of unknown function (DU1801) - - - 0.000000000004641 72.0
HKD1_k127_4741494_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 495.0
HKD1_k127_4741494_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 397.0
HKD1_k127_4741494_2 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 316.0
HKD1_k127_4741494_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000002373 234.0
HKD1_k127_4741494_4 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000002449 79.0
HKD1_k127_474165_0 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 538.0
HKD1_k127_474165_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 486.0
HKD1_k127_474165_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000004715 78.0
HKD1_k127_4748800_0 cellulose binding - - - 4.512e-216 680.0
HKD1_k127_4748800_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 287.0
HKD1_k127_4748800_2 Response regulator, receiver - - - 0.000000000000000004791 88.0
HKD1_k127_4774873_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 532.0
HKD1_k127_4774873_1 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 318.0
HKD1_k127_4780384_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 482.0
HKD1_k127_4800241_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 554.0
HKD1_k127_4800241_1 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007211 260.0
HKD1_k127_4800241_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003209 263.0
HKD1_k127_4800241_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001152 208.0
HKD1_k127_480271_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000103 235.0
HKD1_k127_480271_1 esterase - - - 0.00000000000000000000000000000000000000000000000008229 181.0
HKD1_k127_480271_2 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000001861 188.0
HKD1_k127_480271_3 sensor histidine kinase response - - - 0.000000000000000000000000000008928 131.0
HKD1_k127_480271_4 PFAM Response regulator receiver domain - - - 0.0000000000000000000000163 105.0
HKD1_k127_480271_5 Putative NAD(P)-binding K03499 - - 0.00000000000000000000002278 113.0
HKD1_k127_4804947_0 cellulose binding - - - 0.0 1284.0
HKD1_k127_4805312_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 610.0
HKD1_k127_4810113_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 363.0
HKD1_k127_4812069_0 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443,K16786,K16787 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000008893 228.0
HKD1_k127_4812069_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000001692 169.0
HKD1_k127_4812069_2 Protein of unknown function (DUF2911) - - - 0.0000001262 57.0
HKD1_k127_4817529_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006654 247.0
HKD1_k127_4817529_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000001502 102.0
HKD1_k127_482509_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366 - 1.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 355.0
HKD1_k127_482509_1 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000002526 214.0
HKD1_k127_482509_2 Belongs to the PAPS reductase family. CysH subfamily K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000006737 202.0
HKD1_k127_4827807_0 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 313.0
HKD1_k127_4827807_1 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000001573 208.0
HKD1_k127_4827807_2 - - - - 0.000000000068 68.0
HKD1_k127_4836743_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 455.0
HKD1_k127_4836743_1 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 431.0
HKD1_k127_4836743_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 290.0
HKD1_k127_4836743_3 Belongs to the MraZ family K03925 - - 0.0000000000000000000008417 96.0
HKD1_k127_4836743_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000001726 86.0
HKD1_k127_4836743_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0006633 47.0
HKD1_k127_4838957_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 376.0
HKD1_k127_4838957_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 283.0
HKD1_k127_4838957_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000003617 132.0
HKD1_k127_4838957_3 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000001103 57.0
HKD1_k127_4854706_0 PFAM Tetratricopeptide repeat - - - 0.000000000001127 81.0
HKD1_k127_4854706_1 COG0457 FOG TPR repeat - - - 0.000392 44.0
HKD1_k127_4854706_2 Gram-negative bacterial TonB protein C-terminal - - - 0.0007861 52.0
HKD1_k127_4865311_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000003147 243.0
HKD1_k127_4877012_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 439.0
HKD1_k127_4877012_1 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 321.0
HKD1_k127_4877012_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 318.0
HKD1_k127_4877012_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 295.0
HKD1_k127_4877012_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000275 263.0
HKD1_k127_4878744_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 465.0
HKD1_k127_4878744_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 350.0
HKD1_k127_4878744_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 313.0
HKD1_k127_4878744_3 PFAM ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001686 268.0
HKD1_k127_4878744_4 desaturase K00507 - 1.14.19.1 0.0000000000000000007781 86.0
HKD1_k127_4878744_5 Lipase (class 3) - - - 0.000000000000002371 82.0
HKD1_k127_4878744_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000001099 72.0
HKD1_k127_4879871_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000002228 85.0
HKD1_k127_4887515_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 353.0
HKD1_k127_4887515_1 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 317.0
HKD1_k127_4887515_2 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
HKD1_k127_4888197_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 393.0
HKD1_k127_4888197_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000001467 191.0
HKD1_k127_4888197_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000004451 181.0
HKD1_k127_4888197_3 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000002378 147.0
HKD1_k127_4888197_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000001954 138.0
HKD1_k127_4888197_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000001262 111.0
HKD1_k127_4888197_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000008983 113.0
HKD1_k127_4888197_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000004693 77.0
HKD1_k127_4893220_0 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000003364 196.0
HKD1_k127_4893220_1 electron transfer activity - - - 0.0000000000000000000000000000002312 134.0
HKD1_k127_4893220_2 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000001935 94.0
HKD1_k127_4893220_3 Di-haem oxidoreductase, putative peroxidase - - - 0.000001104 50.0
HKD1_k127_4893255_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 301.0
HKD1_k127_4893255_1 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001699 252.0
HKD1_k127_4893255_2 Protein conserved in bacteria K07011 - - 0.00000000000000000000000000000000000000000000000000000008506 200.0
HKD1_k127_4893255_3 - - - - 0.00000000000000000000000000000000000000000000000007732 188.0
HKD1_k127_4893255_4 Carboxypeptidase regulatory-like domain - - - 0.000006353 50.0
HKD1_k127_4893255_5 Copper binding periplasmic protein CusF K07810 - - 0.0001466 53.0
HKD1_k127_4894641_0 MFS/sugar transport protein K16211 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 609.0
HKD1_k127_4894641_1 Glycogen debranching enzyme, glucanotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 317.0
HKD1_k127_4894641_2 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 284.0
HKD1_k127_4906794_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 537.0
HKD1_k127_4906794_1 Thioesterase-like superfamily - - - 0.00000000000000000000000000000004779 131.0
HKD1_k127_4913825_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 466.0
HKD1_k127_4918499_0 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 373.0
HKD1_k127_4918499_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001235 223.0
HKD1_k127_4918499_2 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000005138 188.0
HKD1_k127_4918499_3 ThiS family K03154 - - 0.000000000002792 68.0
HKD1_k127_4918584_0 Fibronectin-binding A domain protein - - - 0.00000000000000000000000000000000000000000000005075 189.0
HKD1_k127_4918584_1 RDD family - - - 0.00000000002586 76.0
HKD1_k127_4918926_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.545e-300 932.0
HKD1_k127_4918926_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 434.0
HKD1_k127_4918926_2 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 400.0
HKD1_k127_4918926_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000003405 183.0
HKD1_k127_4918926_4 Thioredoxin-like - - - 0.000000000000000000000279 104.0
HKD1_k127_4918926_5 Colicin V production protein K03558 - - 0.0000000000000000001564 95.0
HKD1_k127_4918926_6 Bacterial regulatory protein, Fis family - - - 0.0000000000737 66.0
HKD1_k127_4919787_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.978e-296 918.0
HKD1_k127_4919787_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.289e-210 663.0
HKD1_k127_4919787_2 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 262.0
HKD1_k127_4922383_0 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 297.0
HKD1_k127_4922383_1 - - - - 0.000000005577 63.0
HKD1_k127_4922383_2 PFAM Tetratricopeptide - - - 0.00002509 54.0
HKD1_k127_4926364_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 419.0
HKD1_k127_4926364_1 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000234 155.0
HKD1_k127_4929495_0 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 324.0
HKD1_k127_4929495_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000005621 65.0
HKD1_k127_493370_0 PD-(D/E)XK nuclease superfamily - - - 5.485e-288 920.0
HKD1_k127_493370_1 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000001752 173.0
HKD1_k127_4936321_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 483.0
HKD1_k127_4936321_1 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006808 250.0
HKD1_k127_4936321_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000001088 209.0
HKD1_k127_4936321_3 Binds the 23S rRNA K02909 - - 0.00000000000000138 76.0
HKD1_k127_493784_0 WD40-like Beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000003949 239.0
HKD1_k127_493784_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000004991 167.0
HKD1_k127_493784_2 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000002851 141.0
HKD1_k127_4940914_0 Tricorn protease homolog - - - 6.634e-215 679.0
HKD1_k127_4957080_0 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 479.0
HKD1_k127_4957080_1 Protein of unknown function (DUF1232) - - - 0.00000000000000000000001388 105.0
HKD1_k127_4962782_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 568.0
HKD1_k127_4962782_1 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 438.0
HKD1_k127_4971124_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 2.398e-219 689.0
HKD1_k127_4971124_1 PFAM Transketolase central region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 425.0
HKD1_k127_4971124_2 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 389.0
HKD1_k127_4971124_3 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 393.0
HKD1_k127_4971124_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002529 241.0
HKD1_k127_4971124_5 OsmC-like protein - - - 0.00000000000000000000000000000000000114 143.0
HKD1_k127_4971124_6 Pectinesterase K01051 - 3.1.1.11 0.000000000000000004605 89.0
HKD1_k127_4971124_7 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000003557 70.0
HKD1_k127_497264_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 453.0
HKD1_k127_4977248_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 317.0
HKD1_k127_4977296_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 511.0
HKD1_k127_4977296_1 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 445.0
HKD1_k127_4977296_2 SpoIID LytB domain protein K06381 - - 0.00000000000003529 83.0
HKD1_k127_4979676_0 Peptidase family M49 - - - 5.318e-201 640.0
HKD1_k127_4979676_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 348.0
HKD1_k127_4979676_2 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 331.0
HKD1_k127_4979676_3 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000006131 162.0
HKD1_k127_4979676_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000004383 117.0
HKD1_k127_4988309_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 474.0
HKD1_k127_4988309_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000002622 260.0
HKD1_k127_4988309_2 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000007079 251.0
HKD1_k127_4988309_3 PFAM Major Facilitator Superfamily K08223 - - 0.0000000000007706 76.0
HKD1_k127_4990684_0 GMC oxidoreductase - - - 2.132e-231 729.0
HKD1_k127_4990684_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 337.0
HKD1_k127_4990684_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 298.0
HKD1_k127_4990684_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000005357 189.0
HKD1_k127_4990684_4 BMC K04025 - - 0.00000000000000000000000000000000000000548 152.0
HKD1_k127_4990684_5 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000000001449 153.0
HKD1_k127_4990684_6 - - - - 0.0000000000000000000000000003927 114.0
HKD1_k127_4991324_0 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 468.0
HKD1_k127_4991324_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000009595 193.0
HKD1_k127_4991324_2 RDD family - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000001278 98.0
HKD1_k127_5005014_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000001394 210.0
HKD1_k127_5005014_1 - - - - 0.000000000772 69.0
HKD1_k127_500636_0 Peptidase M14, carboxypeptidase A - - - 2.758e-247 784.0
HKD1_k127_500636_1 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
HKD1_k127_5015653_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 7.08e-209 662.0
HKD1_k127_5015653_1 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002167 283.0
HKD1_k127_5015653_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000002248 164.0
HKD1_k127_5015653_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000008143 170.0
HKD1_k127_5015653_4 Tetratricopeptide repeat - - - 0.0000000000000032 89.0
HKD1_k127_5016947_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 554.0
HKD1_k127_5016947_1 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000004913 149.0
HKD1_k127_5016947_2 - - - - 0.00000000000000000000000000000000001141 138.0
HKD1_k127_5016947_3 Fatty acid desaturase - - - 0.00000000000000000003673 103.0
HKD1_k127_5025972_0 Carboxyl transferase domain - - - 1.192e-219 693.0
HKD1_k127_5025972_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000006118 65.0
HKD1_k127_5044468_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
HKD1_k127_5044468_1 Lipopolysaccharide-assembly - - - 0.00000000000000000000000208 111.0
HKD1_k127_5044468_2 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.0000000000009967 76.0
HKD1_k127_5060308_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 586.0
HKD1_k127_5060308_1 Zn-dependent peptidases K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 488.0
HKD1_k127_5060308_2 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 450.0
HKD1_k127_5060308_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 407.0
HKD1_k127_5060308_4 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 364.0
HKD1_k127_5071101_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.529e-280 872.0
HKD1_k127_5071101_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 466.0
HKD1_k127_5071101_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000004937 231.0
HKD1_k127_5071101_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000002768 170.0
HKD1_k127_5071101_4 SNARE associated Golgi protein - - - 0.0000000000000000000001493 107.0
HKD1_k127_5071101_5 BlaR1 peptidase M56 - - - 0.000000000005197 76.0
HKD1_k127_5071101_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000005574 72.0
HKD1_k127_5071101_7 Putative zinc-finger - GO:0005575,GO:0016020 - 0.00001253 56.0
HKD1_k127_5087652_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000016 289.0
HKD1_k127_5087652_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002371 255.0
HKD1_k127_5087652_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000007808 61.0
HKD1_k127_5089626_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 364.0
HKD1_k127_5089626_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 337.0
HKD1_k127_5089626_2 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 300.0
HKD1_k127_5089626_3 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000001172 141.0
HKD1_k127_5103323_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 3.031e-224 713.0
HKD1_k127_5103323_1 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 469.0
HKD1_k127_5103323_2 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.00000000000006296 79.0
HKD1_k127_5108156_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 468.0
HKD1_k127_5108156_1 virulence factor MVIN family protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 469.0
HKD1_k127_5108156_2 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000001026 177.0
HKD1_k127_5108156_3 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000218 160.0
HKD1_k127_5108156_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000001421 109.0
HKD1_k127_5114494_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002091 271.0
HKD1_k127_5114494_1 threonine synthase activity K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000001626 219.0
HKD1_k127_5114494_2 WD-40 repeat protein - - - 0.0000000000000000000000000000000000000000000000000001041 213.0
HKD1_k127_5114494_3 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000001394 99.0
HKD1_k127_5114494_4 von Willebrand factor, type A - - - 0.000000000000000001716 96.0
HKD1_k127_5114494_5 Ankyrin repeats (many copies) K06867 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - 0.0000259 58.0
HKD1_k127_5127186_0 iron-nicotianamine transmembrane transporter activity - - - 2.882e-285 900.0
HKD1_k127_5127186_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 441.0
HKD1_k127_5127186_2 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 317.0
HKD1_k127_5127186_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000001844 259.0
HKD1_k127_5127186_4 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000001312 139.0
HKD1_k127_5135405_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 3.749e-275 876.0
HKD1_k127_5138174_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 614.0
HKD1_k127_5138174_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 442.0
HKD1_k127_5138174_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 354.0
HKD1_k127_5138174_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000004497 227.0
HKD1_k127_515542_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 433.0
HKD1_k127_515542_1 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001063 286.0
HKD1_k127_515542_2 Methyltransferase type 11 K01990,K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000009763 173.0
HKD1_k127_515542_3 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000000000000000004374 102.0
HKD1_k127_515542_4 enterobactin catabolic process K07214 - - 0.0000000000000005566 83.0
HKD1_k127_515542_5 enterobactin catabolic process K07214 - - 0.0000008514 52.0
HKD1_k127_515542_6 transcription factor binding K02584,K11914 - - 0.00001681 48.0
HKD1_k127_5159041_0 Amidohydrolase family - - - 2.113e-271 861.0
HKD1_k127_5159041_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
HKD1_k127_5159649_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003199 264.0
HKD1_k127_5159649_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000004021 175.0
HKD1_k127_5159649_2 Thioredoxin - - - 0.0000000000000000000002948 111.0
HKD1_k127_5162440_0 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 456.0
HKD1_k127_5162440_1 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 447.0
HKD1_k127_5162440_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 301.0
HKD1_k127_5162440_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004753 227.0
HKD1_k127_5162978_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 433.0
HKD1_k127_5162978_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000008084 111.0
HKD1_k127_5162978_2 Caspase domain K04771 - 3.4.21.107 0.0000000000000000000004216 112.0
HKD1_k127_5162978_3 Tetratricopeptide repeat - - - 0.0005106 53.0
HKD1_k127_5184201_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000002801 255.0
HKD1_k127_5184201_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000277 215.0
HKD1_k127_5184201_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000008893 111.0
HKD1_k127_5184201_3 glucan 1,4-alpha-glucosidase activity K05989,K20541 - 3.2.1.40 0.000000005892 62.0
HKD1_k127_5192076_0 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 301.0
HKD1_k127_5192076_1 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.00000000000000000000000000000007592 125.0
HKD1_k127_519675_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 396.0
HKD1_k127_519675_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 321.0
HKD1_k127_519675_2 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000863 262.0
HKD1_k127_5197644_0 gluconolactonase activity K01053 - 3.1.1.17 2.551e-204 649.0
HKD1_k127_5197644_1 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 334.0
HKD1_k127_5197644_2 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 313.0
HKD1_k127_5197644_3 Haem-degrading - - - 0.00000000000000000000000000000000000001288 150.0
HKD1_k127_5197644_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000116 100.0
HKD1_k127_5204358_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 512.0
HKD1_k127_5204358_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 371.0
HKD1_k127_5204358_2 SMART Transport-associated and nodulation - - - 0.000000000000000000001103 105.0
HKD1_k127_5204358_3 Prokaryotic N-terminal methylation motif K02650 - - 0.0005024 51.0
HKD1_k127_5214137_0 efflux transmembrane transporter activity - - - 8.026e-213 688.0
HKD1_k127_5214137_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000003399 188.0
HKD1_k127_5215095_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 357.0
HKD1_k127_5215095_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000013 211.0
HKD1_k127_5215095_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000002049 92.0
HKD1_k127_5215095_3 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000004147 95.0
HKD1_k127_5240818_0 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000008126 201.0
HKD1_k127_5240818_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000444 198.0
HKD1_k127_5240818_2 Polynucleotide kinase 3 phosphatase - - - 0.000000000000000000000000000000000000000000005982 169.0
HKD1_k127_5247613_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 395.0
HKD1_k127_5247613_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 328.0
HKD1_k127_5247613_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000008785 264.0
HKD1_k127_5247613_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000002056 203.0
HKD1_k127_5247613_4 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000006504 194.0
HKD1_k127_5247613_5 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000003237 66.0
HKD1_k127_5283148_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000002353 231.0
HKD1_k127_5283148_1 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.0000000000000000003916 87.0
HKD1_k127_5283148_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0003855 43.0
HKD1_k127_5284104_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 607.0
HKD1_k127_5284104_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007588 265.0
HKD1_k127_5284104_2 TIGRFAM TonB K03832 - - 0.00000000000000000000000000002387 126.0
HKD1_k127_5284104_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000002381 119.0
HKD1_k127_5284104_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000006226 87.0
HKD1_k127_5284104_5 Tetratricopeptide repeat - - - 0.0000000000695 72.0
HKD1_k127_5286556_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004075 275.0
HKD1_k127_5286556_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000005132 127.0
HKD1_k127_5286556_2 TIGRFAM TonB K03832 - - 0.00003019 56.0
HKD1_k127_5286556_3 Belongs to the peptidase S8 family K01361,K08652,K14647 - 3.4.21.110,3.4.21.96 0.0006313 48.0
HKD1_k127_529672_0 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 416.0
HKD1_k127_529672_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000248 201.0
HKD1_k127_529672_2 Tetratricopeptide repeat - - - 0.0000002794 62.0
HKD1_k127_5296983_0 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 300.0
HKD1_k127_5296983_1 phosphoglycerate mutase - - - 0.00000000000000000000000000003866 125.0
HKD1_k127_5296983_2 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000001062 55.0
HKD1_k127_5298819_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 467.0
HKD1_k127_5298819_1 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
HKD1_k127_5298819_2 Alternative locus ID - - - 0.00000000000000000000000000000000000000000000000000000001855 207.0
HKD1_k127_5298819_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000007027 175.0
HKD1_k127_5298819_4 PHP domain protein K02347 - - 0.000000000000000000000000000000000002394 143.0
HKD1_k127_5302315_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 504.0
HKD1_k127_5302315_1 YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 348.0
HKD1_k127_5302315_2 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000002147 243.0
HKD1_k127_5302315_3 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000003036 188.0
HKD1_k127_5302315_4 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000007024 63.0
HKD1_k127_5303261_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 453.0
HKD1_k127_5303261_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000144 122.0
HKD1_k127_5303261_2 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000005368 113.0
HKD1_k127_5310983_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 2.067e-232 728.0
HKD1_k127_5310983_1 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 580.0
HKD1_k127_5310983_2 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 412.0
HKD1_k127_5320348_0 radical SAM domain protein - - - 1.263e-235 737.0
HKD1_k127_5320348_1 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 323.0
HKD1_k127_5324547_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 421.0
HKD1_k127_5324547_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002239 235.0
HKD1_k127_5324547_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000006353 179.0
HKD1_k127_5324547_3 - - - - 0.000000001482 61.0
HKD1_k127_5331701_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001331 245.0
HKD1_k127_5331701_1 OsmC-like protein K07397 - - 0.00000000000000000000000000008332 121.0
HKD1_k127_5331701_2 Preprotein translocase SecG subunit K03075 - - 0.000001283 56.0
HKD1_k127_5333568_0 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000003344 200.0
HKD1_k127_5333568_1 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000001062 206.0
HKD1_k127_5333568_2 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000008518 132.0
HKD1_k127_5333568_3 Periplasmic or secreted lipoprotein - - - 0.0005274 48.0
HKD1_k127_5336553_0 peptidase M55 D-aminopeptidase K16203 - - 0.00000000000000000000429 97.0
HKD1_k127_5336553_1 - K07403 - - 0.00001405 51.0
HKD1_k127_534191_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008475 279.0
HKD1_k127_534191_1 cellulose binding - - - 0.0000000005691 63.0
HKD1_k127_5356049_0 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 524.0
HKD1_k127_5356049_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 427.0
HKD1_k127_5356049_2 PFAM Isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000004136 199.0
HKD1_k127_5356049_3 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000001949 147.0
HKD1_k127_5356049_4 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000002618 93.0
HKD1_k127_5357295_0 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002398 301.0
HKD1_k127_5357295_1 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 0.00000000000000000000000000000000000000000000000006826 185.0
HKD1_k127_5357295_2 Tetratricopeptide repeat - - - 0.00007004 55.0
HKD1_k127_5358534_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 6.842e-222 698.0
HKD1_k127_5358534_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 340.0
HKD1_k127_5358534_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 312.0
HKD1_k127_5358534_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000001513 256.0
HKD1_k127_537293_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 591.0
HKD1_k127_537293_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 397.0
HKD1_k127_537293_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000001374 197.0
HKD1_k127_5385554_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 480.0
HKD1_k127_5385554_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 341.0
HKD1_k127_5389250_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000085 255.0
HKD1_k127_5389250_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000005903 91.0
HKD1_k127_5389250_2 Molecular chaperone - - - 0.000000000002626 75.0
HKD1_k127_5389250_3 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000002477 67.0
HKD1_k127_5389250_4 - - - - 0.000001178 56.0
HKD1_k127_5390211_0 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000005666 149.0
HKD1_k127_5390211_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000007392 95.0
HKD1_k127_5390211_2 - - - - 0.000002752 54.0
HKD1_k127_5390211_3 chaperone-mediated protein folding - - - 0.00002177 48.0
HKD1_k127_54052_0 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 347.0
HKD1_k127_54052_1 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000002815 111.0
HKD1_k127_54052_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000009166 53.0
HKD1_k127_5408942_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001253 299.0
HKD1_k127_5408942_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000002502 261.0
HKD1_k127_5409538_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 482.0
HKD1_k127_5409538_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 444.0
HKD1_k127_5409538_2 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000003086 137.0
HKD1_k127_5409538_3 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000001508 81.0
HKD1_k127_5411274_0 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 367.0
HKD1_k127_5411274_1 - - - - 0.0000000000000000000000000000000000000000005302 159.0
HKD1_k127_5411274_2 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.00000000000000000000000000000000000000006141 156.0
HKD1_k127_5411274_3 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000001887 108.0
HKD1_k127_5435006_0 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 502.0
HKD1_k127_5435006_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000005768 143.0
HKD1_k127_5435006_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000006907 132.0
HKD1_k127_5436953_0 Cytosine-specific methyltransferase K00558 - 2.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 453.0
HKD1_k127_5436953_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000002259 174.0
HKD1_k127_5446034_0 PFAM Glycosyl hydrolases family 31 K01187 - 3.2.1.20 1.229e-203 665.0
HKD1_k127_5446034_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 397.0
HKD1_k127_5446034_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000035 258.0
HKD1_k127_5469639_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 2.388e-237 753.0
HKD1_k127_5469639_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 434.0
HKD1_k127_5469639_2 Forkhead associated domain - - - 0.000000000000000000000000000000000297 147.0
HKD1_k127_5469639_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000009848 91.0
HKD1_k127_5469639_4 - - - - 0.00000144 57.0
HKD1_k127_5473679_0 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 513.0
HKD1_k127_5473679_1 methyltransferase - - - 0.0000000001717 63.0
HKD1_k127_5475580_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 300.0
HKD1_k127_5475580_1 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000002759 190.0
HKD1_k127_5475580_2 Thioesterase superfamily - - - 0.000000000000000000000000000006548 123.0
HKD1_k127_5477929_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 484.0
HKD1_k127_5477929_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 477.0
HKD1_k127_5477929_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 459.0
HKD1_k127_5493744_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008079 258.0
HKD1_k127_5496796_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 540.0
HKD1_k127_5496796_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 428.0
HKD1_k127_5496796_10 - - - - 0.000008183 49.0
HKD1_k127_5496796_11 PFAM Integrase catalytic region K07497 - - 0.0006157 42.0
HKD1_k127_5496796_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001208 248.0
HKD1_k127_5496796_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008548 244.0
HKD1_k127_5496796_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000001824 150.0
HKD1_k127_5496796_5 Two component regulator propeller - - - 0.00000000000000000000000000001487 134.0
HKD1_k127_5496796_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000001098 105.0
HKD1_k127_5496796_7 - - - - 0.00000002403 55.0
HKD1_k127_5496796_9 COG2801 Transposase and inactivated derivatives K07497 - - 0.000002326 51.0
HKD1_k127_5506169_0 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 9.507e-212 666.0
HKD1_k127_5506169_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 519.0
HKD1_k127_5506169_2 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 414.0
HKD1_k127_5506169_3 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 370.0
HKD1_k127_5506169_4 - - - - 0.0000000000000000000000000000002362 126.0
HKD1_k127_5509426_0 Rossmann fold nucleotide-binding protein involved in DNA uptake - - - 0.0000000000000000000000000000000000000000000000000000000000000001431 237.0
HKD1_k127_5509426_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000000000000000000008001 145.0
HKD1_k127_5509426_2 HpcH/HpaI aldolase/citrate lyase family K08691 - 4.1.3.24,4.1.3.25 0.0000000000003384 76.0
HKD1_k127_551301_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 516.0
HKD1_k127_551301_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 421.0
HKD1_k127_551301_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 416.0
HKD1_k127_551301_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 346.0
HKD1_k127_551301_4 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 340.0
HKD1_k127_551301_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 325.0
HKD1_k127_551301_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001858 281.0
HKD1_k127_551301_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000001042 222.0
HKD1_k127_551301_8 Cell division protein FtsQ K03589 - - 0.000003146 59.0
HKD1_k127_5513196_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000009493 215.0
HKD1_k127_5513196_1 DoxX - - - 0.00000000000000000000000000000000000005097 146.0
HKD1_k127_553514_0 DNA polymerase K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 456.0
HKD1_k127_553514_1 Anti-sigma-K factor rskA - - - 0.0006876 51.0
HKD1_k127_5544924_0 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 609.0
HKD1_k127_5544924_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001226 259.0
HKD1_k127_5544924_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000004164 206.0
HKD1_k127_5554830_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 401.0
HKD1_k127_5554830_1 ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit K02049 - - 0.00000000000000003237 82.0
HKD1_k127_5571962_0 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000001131 196.0
HKD1_k127_5571962_1 Domain of unknown function (DUF4350) - - - 0.0000000000000000000000000000001097 138.0
HKD1_k127_5571962_2 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000004944 63.0
HKD1_k127_5583297_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 573.0
HKD1_k127_5583297_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000009462 154.0
HKD1_k127_5583297_2 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000938 138.0
HKD1_k127_5584760_0 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 306.0
HKD1_k127_5584760_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000001737 136.0
HKD1_k127_5595161_0 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 367.0
HKD1_k127_5599771_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 325.0
HKD1_k127_5599771_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000007373 213.0
HKD1_k127_5599771_2 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000002143 126.0
HKD1_k127_5602088_0 - - - - 0.0000000000000000000008152 99.0
HKD1_k127_5602088_1 Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins - GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.00000001538 65.0
HKD1_k127_5602088_2 Sh3 type 3 domain protein - - - 0.0000003598 62.0
HKD1_k127_5613195_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 443.0
HKD1_k127_5613195_1 HAD-superfamily hydrolase, subfamily IA K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000000000003277 128.0
HKD1_k127_5615048_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 497.0
HKD1_k127_5615048_1 - - - - 0.0000000533 61.0
HKD1_k127_5615442_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 4.405e-200 633.0
HKD1_k127_5615442_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000001675 94.0
HKD1_k127_5617015_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 506.0
HKD1_k127_5617015_1 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 333.0
HKD1_k127_5617015_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000001866 146.0
HKD1_k127_5617015_3 response regulator K22010 - - 0.00000000000000001635 92.0
HKD1_k127_5617015_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000003284 87.0
HKD1_k127_5623918_0 S-adenosylmethionine-dependent methyltransferase K06969,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.191,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000009296 238.0
HKD1_k127_5623918_1 DDE superfamily endonuclease - - - 0.000025 48.0
HKD1_k127_5625172_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.805e-219 704.0
HKD1_k127_5625172_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000005034 84.0
HKD1_k127_5634654_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 471.0
HKD1_k127_5634654_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000006866 184.0
HKD1_k127_5634654_2 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000001678 159.0
HKD1_k127_5636115_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002738 263.0
HKD1_k127_5636115_1 membrane - - - 0.00000000000000000000000000000000000000000000000000007212 211.0
HKD1_k127_565565_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 463.0
HKD1_k127_565565_1 COG1012 NAD-dependent aldehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 224.0
HKD1_k127_565565_2 toxin-antitoxin pair type II binding - - - 0.000000001549 64.0
HKD1_k127_5659294_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 597.0
HKD1_k127_5659294_1 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 383.0
HKD1_k127_5659294_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000001179 246.0
HKD1_k127_5660469_0 Amidohydrolase family - - - 2.075e-247 775.0
HKD1_k127_5660469_1 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 393.0
HKD1_k127_5660469_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000001043 134.0
HKD1_k127_5660469_3 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.0000000000000006139 87.0
HKD1_k127_5666230_0 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 456.0
HKD1_k127_5666230_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 416.0
HKD1_k127_5666230_2 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000009273 180.0
HKD1_k127_5666230_3 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000004237 153.0
HKD1_k127_5666230_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000002268 68.0
HKD1_k127_5666230_5 Protein of unknown function (DUF2889) - - - 0.00004539 53.0
HKD1_k127_5671965_0 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000002452 166.0
HKD1_k127_5671965_1 Alpha galactosidase A K07407 - 3.2.1.22 0.000000000000000000000000000000000000000001736 158.0
HKD1_k127_5676195_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 600.0
HKD1_k127_5676195_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000301 192.0
HKD1_k127_5679422_0 Belongs to the ABC transporter superfamily K10112,K17240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 389.0
HKD1_k127_5679422_1 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 297.0
HKD1_k127_5679422_2 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000004741 230.0
HKD1_k127_5679422_3 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000002217 173.0
HKD1_k127_5679422_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000001468 85.0
HKD1_k127_5680174_0 Peptidase family C25 - - - 0.000000000000002666 89.0
HKD1_k127_5688106_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000002453 153.0
HKD1_k127_5716550_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000003056 226.0
HKD1_k127_5716550_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000171 181.0
HKD1_k127_5716550_2 Tetratricopeptide repeat - - - 0.0001722 53.0
HKD1_k127_5721081_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 450.0
HKD1_k127_5721081_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000004015 188.0
HKD1_k127_5726171_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 372.0
HKD1_k127_5726171_1 Alternative locus ID - - - 0.000000000000000005439 92.0
HKD1_k127_5726793_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 353.0
HKD1_k127_5726793_1 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003847 282.0
HKD1_k127_5726793_2 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000003782 173.0
HKD1_k127_5726793_3 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000001232 113.0
HKD1_k127_5726793_4 - - - - 0.0000000000000000000000006488 109.0
HKD1_k127_572877_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 392.0
HKD1_k127_572877_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000001496 222.0
HKD1_k127_572877_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000004261 177.0
HKD1_k127_5733811_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.221e-236 742.0
HKD1_k127_5733811_1 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000002185 211.0
HKD1_k127_5733811_2 Trm112p-like protein K09791 - - 0.000000000000000000000003066 102.0
HKD1_k127_5733811_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000001133 64.0
HKD1_k127_5733811_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0001929 48.0
HKD1_k127_5742613_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 495.0
HKD1_k127_5742613_1 methyltransferase - - - 0.0000000000000000000000000000001614 130.0
HKD1_k127_5751867_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 439.0
HKD1_k127_5751867_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002801 252.0
HKD1_k127_5751867_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000006911 111.0
HKD1_k127_5751867_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000001261 108.0
HKD1_k127_5769143_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 463.0
HKD1_k127_5769143_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000001114 89.0
HKD1_k127_57719_0 SMART Elongator protein 3 MiaB NifB - - - 2.927e-228 740.0
HKD1_k127_57719_1 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 522.0
HKD1_k127_57719_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 502.0
HKD1_k127_57719_3 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 394.0
HKD1_k127_57719_4 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 297.0
HKD1_k127_57719_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000005869 238.0
HKD1_k127_57719_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000001703 177.0
HKD1_k127_57719_7 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000006787 159.0
HKD1_k127_57719_8 shape-determining protein MreD K03571 - - 0.0000000000287 70.0
HKD1_k127_57719_9 Putative peptidoglycan binding domain - - - 0.000000743 59.0
HKD1_k127_5801070_0 Pfam Cys Met metabolism K01758 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 341.0
HKD1_k127_5801070_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 305.0
HKD1_k127_5801070_2 AsnC family K03719 - - 0.00000000000000001087 85.0
HKD1_k127_582337_0 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 327.0
HKD1_k127_582337_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005539 267.0
HKD1_k127_5825798_0 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
HKD1_k127_5825798_1 COG2031 Short chain fatty acids transporter K02106 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000007376 65.0
HKD1_k127_5838430_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
HKD1_k127_5838430_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000001919 160.0
HKD1_k127_5838430_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000003778 85.0
HKD1_k127_5842213_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 297.0
HKD1_k127_5843932_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 599.0
HKD1_k127_5843932_1 Protoporphyrin IX K03403 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 520.0
HKD1_k127_5843932_2 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.0000000004764 73.0
HKD1_k127_5843932_3 Histidine kinase A domain protein - - - 0.00006867 56.0
HKD1_k127_5844269_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 413.0
HKD1_k127_5844269_1 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000001974 198.0
HKD1_k127_5844269_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000002497 180.0
HKD1_k127_5860057_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.245e-300 941.0
HKD1_k127_5860057_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000002866 216.0
HKD1_k127_5860057_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000001255 70.0
HKD1_k127_5868522_0 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 290.0
HKD1_k127_5868522_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007922 276.0
HKD1_k127_5868522_2 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000003518 196.0
HKD1_k127_5868522_3 Erythromycin esterase K06880 - - 0.00000000000000000001244 93.0
HKD1_k127_5873272_0 Tricorn protease C1 domain K08676 - - 1.619e-231 730.0
HKD1_k127_5873272_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 486.0
HKD1_k127_5873272_2 Predicted Zn-dependent protease (DUF2268) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005015 282.0
HKD1_k127_5873272_3 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000004958 184.0
HKD1_k127_5875914_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 316.0
HKD1_k127_5875914_1 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000374 203.0
HKD1_k127_5902208_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 547.0
HKD1_k127_5902208_1 Sodium/hydrogen exchanger family K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 527.0
HKD1_k127_5902208_10 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000009321 95.0
HKD1_k127_5902208_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009286 299.0
HKD1_k127_5902208_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
HKD1_k127_5902208_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009602 249.0
HKD1_k127_5902208_5 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008624 243.0
HKD1_k127_5902208_6 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000004132 225.0
HKD1_k127_5902208_7 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788 - - 0.0000000000000000000000000000000000000000000000000000008986 194.0
HKD1_k127_5902208_8 - - - - 0.0000000000000000000000000000000000000000000000003268 180.0
HKD1_k127_5902208_9 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000264 141.0
HKD1_k127_5905058_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.238e-320 1009.0
HKD1_k127_5905058_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 299.0
HKD1_k127_5905058_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000356 229.0
HKD1_k127_5905058_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000271 124.0
HKD1_k127_5928330_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 327.0
HKD1_k127_5928330_1 Peptidase family M28 - - - 0.000008291 56.0
HKD1_k127_5928330_2 integral membrane protein - - - 0.00007403 48.0
HKD1_k127_59356_0 protein histidine kinase activity - - - 1.327e-201 637.0
HKD1_k127_59356_1 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 545.0
HKD1_k127_59356_2 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 475.0
HKD1_k127_59356_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 441.0
HKD1_k127_5940606_0 Glycogen debranching enzyme - - - 1.595e-240 762.0
HKD1_k127_5940606_1 hemolysin - - - 0.00000000000000000000000000000000000000000000000000000000000000002705 235.0
HKD1_k127_5940606_2 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000001573 169.0
HKD1_k127_5940606_3 PFAM Mannosyl oligosaccharide glucosidase - - - 0.000000000000000000000000000000000002522 139.0
HKD1_k127_5940606_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000006543 131.0
HKD1_k127_5940606_5 DinB family - - - 0.0000000000000000000000002347 112.0
HKD1_k127_5940606_6 Transport and Golgi organisation 2 - - - 0.000000000000000000001903 99.0
HKD1_k127_5940606_7 Short chain dehydrogenase - - - 0.00000000000000017 80.0
HKD1_k127_5949219_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 418.0
HKD1_k127_5949219_1 Penicillin amidase - - - 0.0000000000000000000000000000000000000000000001251 174.0
HKD1_k127_5958675_0 PFAM Peptidase M20 - - - 0.0000000000000000000000000000000000000000000000000000000000007775 225.0
HKD1_k127_5958675_1 aminopeptidase activity - - - 0.0000000000000000000001724 103.0
HKD1_k127_5958675_2 PFAM von Willebrand factor type A - - - 0.000000000000000901 84.0
HKD1_k127_5958675_3 deoxyhypusine monooxygenase activity - - - 0.000002846 60.0
HKD1_k127_5958675_4 Ami_2 - - - 0.0001545 47.0
HKD1_k127_5969188_0 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 342.0
HKD1_k127_5969188_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 335.0
HKD1_k127_5969188_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 302.0
HKD1_k127_5969188_3 Pfam Glycosyl transferase family 2 K21366 - 2.4.1.122 0.0000000000000000000000000000000000000000000000000000000000000000000002359 248.0
HKD1_k127_5969188_4 Core-2/I-Branching enzyme - - - 0.0000000000000000000000000000000000000226 155.0
HKD1_k127_5969775_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 603.0
HKD1_k127_5969775_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 359.0
HKD1_k127_5969775_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000003044 204.0
HKD1_k127_5974048_0 Sulfate permease family - - - 6.307e-240 755.0
HKD1_k127_5974048_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 468.0
HKD1_k127_5974048_2 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 393.0
HKD1_k127_5974048_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 253.0
HKD1_k127_5974048_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000002406 217.0
HKD1_k127_5986408_0 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 333.0
HKD1_k127_5986408_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000005609 171.0
HKD1_k127_5990532_0 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 338.0
HKD1_k127_5990532_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 309.0
HKD1_k127_5990532_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000002698 94.0
HKD1_k127_5999675_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 519.0
HKD1_k127_5999675_1 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 493.0
HKD1_k127_5999675_2 Serine threonine protein kinase involved in cell cycle control - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 398.0
HKD1_k127_5999675_3 lactoylglutathione lyase activity K11210,K21253,K21264,K21265 GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 2.5.1.18 0.0000000000000000000000000000000000000000000000004725 179.0
HKD1_k127_6028219_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 385.0
HKD1_k127_6028219_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 320.0
HKD1_k127_6028219_2 Hydrolase, P-loop family K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000002919 98.0
HKD1_k127_6030285_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.024e-228 715.0
HKD1_k127_6030285_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000003925 254.0
HKD1_k127_6047733_0 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000002144 238.0
HKD1_k127_6047733_1 PFAM Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000001731 185.0
HKD1_k127_6047733_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000001163 154.0
HKD1_k127_6047733_3 PFAM Major Facilitator Superfamily K08223 - - 0.0000000000216 67.0
HKD1_k127_604999_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000008101 191.0
HKD1_k127_604999_1 - - - - 0.00000000000000000000000219 110.0
HKD1_k127_604999_2 Putative adhesin - - - 0.00006956 54.0
HKD1_k127_6055132_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 394.0
HKD1_k127_6055132_1 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000002329 201.0
HKD1_k127_6055132_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000001042 153.0
HKD1_k127_6055132_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000003742 125.0
HKD1_k127_6055132_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000004405 116.0
HKD1_k127_6055132_5 Caspase domain - - - 0.000001407 61.0
HKD1_k127_605697_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 266.0
HKD1_k127_605697_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000276 119.0
HKD1_k127_605697_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0007327 51.0
HKD1_k127_6072406_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001429 281.0
HKD1_k127_6072406_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000005082 76.0
HKD1_k127_6072406_2 Amidohydrolase K07045 - - 0.0002643 43.0
HKD1_k127_6073777_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 476.0
HKD1_k127_6073777_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000205 241.0
HKD1_k127_6073777_2 Nudix hydrolase K03574 - 3.6.1.55 0.00000000000000000001844 94.0
HKD1_k127_6073777_3 Redoxin - - - 0.0000000000003052 73.0
HKD1_k127_6073777_4 Redoxin K03564 - 1.11.1.15 0.0000151 51.0
HKD1_k127_6084877_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.633e-219 685.0
HKD1_k127_6084877_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0001945 46.0
HKD1_k127_6098607_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 512.0
HKD1_k127_6098607_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 448.0
HKD1_k127_6098607_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000001016 79.0
HKD1_k127_6098607_3 Endonuclease Exonuclease Phosphatase K07004 - - 0.0006133 53.0
HKD1_k127_6098607_4 SMART Integrin alpha beta-propellor repeat protein K01127 - 3.1.4.50 0.0006133 53.0
HKD1_k127_6107850_0 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 382.0
HKD1_k127_6107850_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 344.0
HKD1_k127_6107850_2 A-macroglobulin receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 367.0
HKD1_k127_6107850_3 TIGRFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.000000000000000000000001416 107.0
HKD1_k127_6107850_4 PFAM TonB-dependent Receptor Plug - - - 0.000000007487 70.0
HKD1_k127_6114125_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 1.079e-290 910.0
HKD1_k127_6120995_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.549e-238 754.0
HKD1_k127_6120995_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 527.0
HKD1_k127_6122628_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 467.0
HKD1_k127_6122628_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000005618 78.0
HKD1_k127_6122791_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1043.0
HKD1_k127_6122791_1 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000003594 164.0
HKD1_k127_6122791_2 signal transduction histidine kinase - - - 0.0000000000000000000008409 106.0
HKD1_k127_6122791_3 efflux transmembrane transporter activity K02004 - - 0.000008339 49.0
HKD1_k127_6122791_4 Domain of unknown function (DUF4440) - - - 0.0007747 43.0
HKD1_k127_6130101_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 441.0
HKD1_k127_6130101_1 Peptidase, M28 - - - 0.00000000000000000000000003354 122.0
HKD1_k127_614329_0 Bacterial extracellular solute-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 409.0
HKD1_k127_614329_1 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 406.0
HKD1_k127_614329_2 TIGRFAM sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 295.0
HKD1_k127_614329_3 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001186 271.0
HKD1_k127_614329_4 phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000002747 189.0
HKD1_k127_6153567_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.342e-301 941.0
HKD1_k127_6153567_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000001593 237.0
HKD1_k127_6153567_2 Alpha beta hydrolase superfamily - - - 0.0000000000001791 78.0
HKD1_k127_6155239_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 400.0
HKD1_k127_6155239_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000001969 66.0
HKD1_k127_615667_0 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 409.0
HKD1_k127_615667_1 Protein of unknown function (DUF2911) - - - 0.00000000000001396 81.0
HKD1_k127_6160082_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 602.0
HKD1_k127_6160082_1 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 401.0
HKD1_k127_6176886_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 418.0
HKD1_k127_6176886_1 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 407.0
HKD1_k127_6183004_0 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000007068 210.0
HKD1_k127_6183004_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000005042 188.0
HKD1_k127_6191543_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000194 215.0
HKD1_k127_6191543_1 - - - - 0.0005219 53.0
HKD1_k127_621216_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000001044 186.0
HKD1_k127_621216_1 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000009955 103.0
HKD1_k127_621216_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000611 63.0
HKD1_k127_6222924_0 Cytochrome c K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 437.0
HKD1_k127_6222924_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 405.0
HKD1_k127_6222924_2 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 293.0
HKD1_k127_6222924_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000003639 225.0
HKD1_k127_6222924_4 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000001567 163.0
HKD1_k127_6222924_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000007653 50.0
HKD1_k127_6224703_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 490.0
HKD1_k127_6224703_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000009618 112.0
HKD1_k127_6224703_2 PFAM Tetratricopeptide repeat - - - 0.00000000008923 73.0
HKD1_k127_6227690_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 609.0
HKD1_k127_6227690_1 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 350.0
HKD1_k127_6227690_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 315.0
HKD1_k127_6227690_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000003012 233.0
HKD1_k127_6240470_0 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 3.734e-207 659.0
HKD1_k127_6240470_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 601.0
HKD1_k127_6240470_2 PFAM alpha-L-rhamnosidase K05989 - 3.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 582.0
HKD1_k127_6240470_3 xylulokinase activity K00848,K00851,K00854 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.12,2.7.1.17,2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 421.0
HKD1_k127_6240470_4 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 333.0
HKD1_k127_6240470_5 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000000009882 194.0
HKD1_k127_6267120_0 ABC transporter K15738 - - 1.693e-205 657.0
HKD1_k127_6267120_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 342.0
HKD1_k127_6267120_2 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000001914 96.0
HKD1_k127_6269077_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 571.0
HKD1_k127_6269077_1 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 570.0
HKD1_k127_6269077_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 508.0
HKD1_k127_6269077_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006662 248.0
HKD1_k127_6269077_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000004532 221.0
HKD1_k127_6269077_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000009786 211.0
HKD1_k127_6269077_6 Transcriptional regulator - - - 0.000000000000000000000000007606 115.0
HKD1_k127_6269400_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 542.0
HKD1_k127_6269400_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 297.0
HKD1_k127_6269400_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 296.0
HKD1_k127_6269400_3 Domain of unknown function (DUF1992) - - - 0.00000000000000005638 92.0
HKD1_k127_6269400_4 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000001774 80.0
HKD1_k127_6285944_0 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 362.0
HKD1_k127_6285944_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
HKD1_k127_6285944_2 - - - - 0.0002075 48.0
HKD1_k127_6286182_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.623e-314 978.0
HKD1_k127_6286182_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.405e-247 773.0
HKD1_k127_6286182_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 1.2e-201 636.0
HKD1_k127_6286182_3 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 342.0
HKD1_k127_6286182_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000001937 199.0
HKD1_k127_6286182_5 - - - - 0.0000000000000000000000000000000000000000000000001385 184.0
HKD1_k127_6286182_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000002029 148.0
HKD1_k127_6297501_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 411.0
HKD1_k127_6297501_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004312 243.0
HKD1_k127_6297501_2 Peptidoglycan-binding domain 1 protein - - - 0.0000009255 59.0
HKD1_k127_6297844_0 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000007849 221.0
HKD1_k127_6297844_1 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000002608 201.0
HKD1_k127_6297844_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000729 131.0
HKD1_k127_6297844_3 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.0000000000000000000001988 101.0
HKD1_k127_6297844_4 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.00000003916 61.0
HKD1_k127_632254_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 332.0
HKD1_k127_632254_1 oxidoreductase activity - - - 0.000000000000000000000000000000000001197 156.0
HKD1_k127_6322888_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 548.0
HKD1_k127_6322888_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 375.0
HKD1_k127_6325559_0 Sigma-54 dependent transcriptional regulator K14414 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009372 268.0
HKD1_k127_6325559_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000001915 126.0
HKD1_k127_6331026_0 choline dehydrogenase activity - - - 6.629e-271 841.0
HKD1_k127_6331026_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 465.0
HKD1_k127_6331026_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000002481 97.0
HKD1_k127_6333092_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 442.0
HKD1_k127_6333092_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 304.0
HKD1_k127_6333092_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001659 171.0
HKD1_k127_6333092_3 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000002087 83.0
HKD1_k127_6333092_4 membrane protein domain - - - 0.000000000005515 75.0
HKD1_k127_6337635_0 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 612.0
HKD1_k127_6337635_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000002438 155.0
HKD1_k127_6337635_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000008347 136.0
HKD1_k127_6337635_3 von Willebrand factor, type A - - - 0.00000000000000000000000000000001217 141.0
HKD1_k127_6345554_0 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 411.0
HKD1_k127_6345554_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 273.0
HKD1_k127_6364483_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 522.0
HKD1_k127_6364483_1 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000001638 71.0
HKD1_k127_6368209_0 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000001624 183.0
HKD1_k127_6368209_1 Tetratricopeptide repeat - - - 0.0000000000000001288 90.0
HKD1_k127_6381682_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000002364 91.0
HKD1_k127_6381682_1 outer membrane efflux protein K15725 - - 0.00000000000000006501 94.0
HKD1_k127_6383281_0 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000003813 162.0
HKD1_k127_6383281_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000009933 126.0
HKD1_k127_6388623_0 Sigma-70 region 2 K03088 - - 7.882e-194 611.0
HKD1_k127_6388623_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000003037 201.0
HKD1_k127_6388623_2 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000002417 181.0
HKD1_k127_6388623_3 AMP binding - - - 0.00000000000000000000000000003076 123.0
HKD1_k127_6388623_4 Universal stress protein - - - 0.0009281 50.0
HKD1_k127_6398765_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 426.0
HKD1_k127_6398765_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000002207 209.0
HKD1_k127_6409046_0 MacB-like periplasmic core domain - - - 2.113e-241 775.0
HKD1_k127_6416814_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.144e-206 655.0
HKD1_k127_6437298_0 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000005754 187.0
HKD1_k127_6437298_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000005146 86.0
HKD1_k127_6443801_0 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000001899 261.0
HKD1_k127_6443801_1 PFAM Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000003788 251.0
HKD1_k127_6443801_2 Beta-lactamase - - - 0.000000000000000000000000000000000001602 159.0
HKD1_k127_6462699_0 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 519.0
HKD1_k127_6475418_0 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 319.0
HKD1_k127_6475418_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007316 280.0
HKD1_k127_6475418_2 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000006862 231.0
HKD1_k127_6475418_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000003278 104.0
HKD1_k127_6493798_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1039.0
HKD1_k127_6493798_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 332.0
HKD1_k127_6493855_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 400.0
HKD1_k127_6493855_1 PFAM AraC-type transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001717 224.0
HKD1_k127_6497198_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 2.605e-213 690.0
HKD1_k127_6497198_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000203 230.0
HKD1_k127_6497198_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.00000000000000000000000000000000000000000000001004 188.0
HKD1_k127_6516379_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.135e-265 832.0
HKD1_k127_6516379_1 PFAM YdjC family protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 299.0
HKD1_k127_6516379_2 Ankyrin repeats (3 copies) K06867 - - 0.000000001325 71.0
HKD1_k127_6518546_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000002711 222.0
HKD1_k127_6518546_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000006159 78.0
HKD1_k127_6555451_0 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 501.0
HKD1_k127_6555451_1 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000001083 149.0
HKD1_k127_6591238_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 424.0
HKD1_k127_6591238_1 heat shock protein 70 K04043,K04044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 372.0
HKD1_k127_6591238_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000006687 147.0
HKD1_k127_6591238_3 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000421 118.0
HKD1_k127_6591238_4 Iron-sulphur cluster assembly - - - 0.0000000000000000000004288 96.0
HKD1_k127_6591238_5 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000002863 85.0
HKD1_k127_659633_0 MacB-like periplasmic core domain - - - 7.484e-239 764.0
HKD1_k127_659633_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 375.0
HKD1_k127_659633_2 efflux transmembrane transporter activity - - - 0.000000000000000000000004276 104.0
HKD1_k127_6599692_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 391.0
HKD1_k127_6599692_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 345.0
HKD1_k127_6599692_2 transcriptional regulator, RpiR family - - - 0.00000000000000000005221 102.0
HKD1_k127_6599692_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000002702 59.0
HKD1_k127_6601861_0 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002756 277.0
HKD1_k127_6601861_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000003307 141.0
HKD1_k127_6602545_0 N-4 methylation of cytosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 454.0
HKD1_k127_6602545_1 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 379.0
HKD1_k127_6602545_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000005439 228.0
HKD1_k127_6602545_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000002246 154.0
HKD1_k127_6602545_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0001318 46.0
HKD1_k127_6603742_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 506.0
HKD1_k127_6603742_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 327.0
HKD1_k127_6603742_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000004476 178.0
HKD1_k127_6603742_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000001064 112.0
HKD1_k127_6603742_4 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000001627 109.0
HKD1_k127_6603742_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000926 100.0
HKD1_k127_6604721_0 COGs COG3653 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 479.0
HKD1_k127_6604721_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 302.0
HKD1_k127_6606027_0 HD superfamily K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 301.0
HKD1_k127_6606027_1 PFAM Response regulator receiver domain K02483,K18344 - - 0.0000000000000000000000000000000000000000000000000000005089 200.0
HKD1_k127_6606027_2 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0004366 53.0
HKD1_k127_6606708_0 PAS domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000005825 222.0
HKD1_k127_6606708_1 Transcriptional regulatory protein, C terminal K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000005326 149.0
HKD1_k127_661672_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.556e-312 977.0
HKD1_k127_661672_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 316.0
HKD1_k127_661672_2 Luciferase-like monooxygenase - - - 0.00000000000008283 72.0
HKD1_k127_6617087_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 456.0
HKD1_k127_6617087_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 411.0
HKD1_k127_6617087_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000005033 227.0
HKD1_k127_6617087_3 bis(5'-adenosyl)-triphosphatase activity K02503 - - 0.000000000000000000000000000000000000000000000201 171.0
HKD1_k127_6617087_4 TIGRFAM TonB K03832 - - 0.0000000456 61.0
HKD1_k127_6619583_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000001588 186.0
HKD1_k127_6619583_1 PFAM Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000000000000000000000008288 166.0
HKD1_k127_6619583_2 Polysaccharide deacetylase - - - 0.00000005633 63.0
HKD1_k127_6626747_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 546.0
HKD1_k127_6626747_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000002657 215.0
HKD1_k127_6626747_2 efflux transmembrane transporter activity - - - 0.00000000006931 63.0
HKD1_k127_6626747_3 Tetratricopeptide repeat - - - 0.000002843 59.0
HKD1_k127_6626747_4 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00002675 56.0
HKD1_k127_6635757_0 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 391.0
HKD1_k127_6635757_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000003655 259.0
HKD1_k127_6635757_2 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000206 223.0
HKD1_k127_6635757_3 Domain of unknown function (DUF309) K09763 - - 0.000000000000002996 82.0
HKD1_k127_6635757_4 similarity to SP Q54513 - - - 0.000000000000006193 77.0
HKD1_k127_6643267_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 359.0
HKD1_k127_6643267_1 - - - - 0.00000000000000000000000000002413 124.0
HKD1_k127_6643267_2 Cold shock protein K03704 - - 0.00000000000000000000004964 102.0
HKD1_k127_6643267_3 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.000000000000003557 79.0
HKD1_k127_665085_0 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 308.0
HKD1_k127_665085_1 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000014 117.0
HKD1_k127_6654405_0 PFAM peptidase M16 domain protein K07263 - - 0.0000000000000000000000000001031 133.0
HKD1_k127_6654405_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000001367 97.0
HKD1_k127_6669423_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 409.0
HKD1_k127_6669423_2 general stress protein - - - 0.00001164 54.0
HKD1_k127_6673027_0 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 349.0
HKD1_k127_6673027_1 CarD-like/TRCF domain K07736 - - 0.000000000000000000007915 98.0
HKD1_k127_6677211_0 Domain of unknown function (DUF3536) - - - 7.405e-231 741.0
HKD1_k127_6677211_1 von Willebrand factor, type A - - - 0.000000000000000000000000000139 132.0
HKD1_k127_6677211_2 Beta-lactamase - - - 0.000000000000000000000000005719 114.0
HKD1_k127_6677211_3 peptidyl-tyrosine sulfation - - - 0.0002543 44.0
HKD1_k127_6691867_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 601.0
HKD1_k127_6691867_1 Xylose isomerase domain protein TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 290.0
HKD1_k127_6691867_2 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000001314 208.0
HKD1_k127_6691867_3 Methane oxygenase PmoA - - - 0.0000000000000000000000000000006039 125.0
HKD1_k127_6696962_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 389.0
HKD1_k127_6696962_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000238 208.0
HKD1_k127_6696962_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000001785 165.0
HKD1_k127_6696962_3 Bacterial membrane protein YfhO - - - 0.0000000000000000000003221 110.0
HKD1_k127_6696962_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000006403 86.0
HKD1_k127_6696962_5 TIGRFAM TonB family K03832 - - 0.0000032 51.0
HKD1_k127_6696962_6 SnoaL-like domain - - - 0.00002397 49.0
HKD1_k127_6697919_0 PrkA AAA domain protein K07180 - - 1.555e-298 927.0
HKD1_k127_6697919_1 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000002992 203.0
HKD1_k127_6698350_0 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 298.0
HKD1_k127_6720140_0 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000001211 205.0
HKD1_k127_6720140_1 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000000003049 156.0
HKD1_k127_6734219_0 AMP-binding enzyme K00666 - - 5.604e-225 710.0
HKD1_k127_6734219_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000007926 156.0
HKD1_k127_6734219_2 Transcription factor zinc-finger K09981 - - 0.000000000001378 72.0
HKD1_k127_6740454_0 Domain of unknown function (DUF1707) - - - 0.0000001495 60.0
HKD1_k127_6740454_1 Tetratricopeptide repeat - - - 0.0002861 52.0
HKD1_k127_6748895_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 503.0
HKD1_k127_6748895_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 310.0
HKD1_k127_6748895_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000009934 127.0
HKD1_k127_6748895_3 - - - - 0.0000000000162 69.0
HKD1_k127_6749155_0 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
HKD1_k127_6749155_2 Alpha/beta hydrolase family - - - 0.00000008294 59.0
HKD1_k127_675582_0 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000005462 73.0
HKD1_k127_675582_1 - - - - 0.000000002257 69.0
HKD1_k127_676240_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 479.0
HKD1_k127_676240_1 - - - - 0.00000000000004151 75.0
HKD1_k127_6772123_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.946e-201 657.0
HKD1_k127_6772123_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 459.0
HKD1_k127_6772123_2 response regulator K07685 - - 0.0000000000000000000000000000000000000000000000001365 186.0
HKD1_k127_6772123_3 Winged helix DNA-binding domain - - - 0.000000000000000000009095 97.0
HKD1_k127_6777058_0 PFAM Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002698 273.0
HKD1_k127_6777058_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000614 213.0
HKD1_k127_6777058_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000103 201.0
HKD1_k127_6777058_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000000000002932 149.0
HKD1_k127_6777058_4 Putative Ig domain - - - 0.0000000000000000000000000000004797 131.0
HKD1_k127_6780600_0 D-galactarate dehydratase Altronate K01685,K01708 - 4.2.1.42,4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 375.0
HKD1_k127_6786121_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 564.0
HKD1_k127_6786121_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 325.0
HKD1_k127_6786121_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000815 114.0
HKD1_k127_6795968_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1316.0
HKD1_k127_6795968_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 545.0
HKD1_k127_6795968_2 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001921 265.0
HKD1_k127_6795968_3 efflux transmembrane transporter activity - - - 0.00001551 48.0
HKD1_k127_6805106_0 Sortilin, neurotensin receptor 3, - - - 3.865e-216 688.0
HKD1_k127_6807455_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 387.0
HKD1_k127_6807455_1 Universal stress protein family - - - 0.0000000000000000000000000000000000000000001249 171.0
HKD1_k127_6807455_2 AMP binding K06149 - - 0.00000000000000000000000000004595 121.0
HKD1_k127_6807455_3 SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 - - 0.000000000000000000000001163 108.0
HKD1_k127_6810834_0 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 344.0
HKD1_k127_6810834_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 291.0
HKD1_k127_6810834_2 synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000001683 137.0
HKD1_k127_6818723_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 5.159e-271 856.0
HKD1_k127_6818723_1 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 534.0
HKD1_k127_6818723_2 COG3104 Dipeptide tripeptide permease K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 298.0
HKD1_k127_6818723_3 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000001863 188.0
HKD1_k127_6818723_4 PFAM Pyrrolo-quinoline quinone - - - 0.000000000000126 80.0
HKD1_k127_6818779_0 DEAD DEAH box helicase K03724 - - 1.615e-225 708.0
HKD1_k127_6819181_0 ABC-type molybdate transport system, ATPase component K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000009655 250.0
HKD1_k127_6819181_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000005517 201.0
HKD1_k127_6819181_2 Cytidylate kinase-like family K00760 - 2.4.2.8 0.0000000000000000000000000000000002422 141.0
HKD1_k127_6819181_3 molybdate ABC transporter, permease protein K02017,K02018 - 3.6.3.29 0.000000000000000006946 84.0
HKD1_k127_6831181_0 AAA domain - - - 4.533e-234 742.0
HKD1_k127_6831181_1 Phosphate acyltransferases K01897 - 6.2.1.3 4.825e-196 632.0
HKD1_k127_6840929_0 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000001478 218.0
HKD1_k127_6840929_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000002928 220.0
HKD1_k127_6840929_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000001045 50.0
HKD1_k127_6858639_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 416.0
HKD1_k127_6858639_1 methyltransferase activity K21310 - 2.1.1.334 0.0000001599 55.0
HKD1_k127_6865573_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 502.0
HKD1_k127_6865573_1 glutamate-cysteine ligase activity K00836 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000001434 201.0
HKD1_k127_6865573_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000001561 204.0
HKD1_k127_6874119_0 ThiC-associated domain K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.634e-312 967.0
HKD1_k127_6874119_1 Periplasmic binding protein K02016 - - 0.0000000000000000000001426 98.0
HKD1_k127_6874119_2 Putative restriction endonuclease - - - 0.00000000000000000007383 90.0
HKD1_k127_6874119_3 Putative restriction endonuclease - - - 0.000001096 54.0
HKD1_k127_6902324_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1017.0
HKD1_k127_6902324_1 ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 388.0
HKD1_k127_6902324_2 Redoxin - - - 0.000000000000000000000000000000000009568 150.0
HKD1_k127_6902324_3 - - - - 0.000105 52.0
HKD1_k127_6923859_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000002835 244.0
HKD1_k127_6923859_1 TonB-dependent receptor - - - 0.000007211 52.0
HKD1_k127_6924220_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 356.0
HKD1_k127_6924220_1 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000104 254.0
HKD1_k127_6924220_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000001595 112.0
HKD1_k127_6930958_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 334.0
HKD1_k127_6930958_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000002039 119.0
HKD1_k127_693255_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000003515 166.0
HKD1_k127_6933257_0 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 496.0
HKD1_k127_6933257_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 387.0
HKD1_k127_6940682_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 362.0
HKD1_k127_6940682_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 315.0
HKD1_k127_6940682_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000003388 51.0
HKD1_k127_6944432_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 364.0
HKD1_k127_6944432_1 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000004049 126.0
HKD1_k127_6944432_2 Thioesterase superfamily K07107 - - 0.00000000000000000000000585 106.0
HKD1_k127_6944432_3 Transcriptional regulator - - - 0.00000000000000718 76.0
HKD1_k127_6944432_4 RNA-binding S4 domain protein - - - 0.00000000000002565 77.0
HKD1_k127_6951584_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 331.0
HKD1_k127_6951584_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008516 267.0
HKD1_k127_6951584_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000001066 217.0
HKD1_k127_6951584_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000007641 74.0
HKD1_k127_6956610_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 419.0
HKD1_k127_6958739_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004095 295.0
HKD1_k127_6958739_1 Cupin - - - 0.00000000000000000000000000000005967 132.0
HKD1_k127_6958739_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000003725 113.0
HKD1_k127_6958973_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 501.0
HKD1_k127_6958973_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 415.0
HKD1_k127_6958973_2 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000001411 124.0
HKD1_k127_6963149_0 Peptidase M14, carboxypeptidase A - - - 3.351e-289 899.0
HKD1_k127_6964983_0 Large extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000000009851 176.0
HKD1_k127_6964983_1 - - - - 0.00000000002716 70.0
HKD1_k127_6966919_0 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 383.0
HKD1_k127_6966919_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 320.0
HKD1_k127_6966919_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002536 286.0
HKD1_k127_6966919_3 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000000002042 137.0
HKD1_k127_6966919_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K15583 - - 0.00000000000000000000000000000008746 127.0
HKD1_k127_6966919_5 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000006123 110.0
HKD1_k127_6966919_6 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0000000000000000000108 108.0
HKD1_k127_6973028_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 562.0
HKD1_k127_6973028_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.000000000002857 72.0
HKD1_k127_6973561_0 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 514.0
HKD1_k127_6973561_1 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 325.0
HKD1_k127_6973561_2 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 313.0
HKD1_k127_6973561_3 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000007933 199.0
HKD1_k127_6973561_4 Prolyl oligopeptidase family - - - 0.000000000000000000000000004731 122.0
HKD1_k127_6973561_5 - - - - 0.0000000004147 68.0
HKD1_k127_6973561_6 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0007044 46.0
HKD1_k127_6978032_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004348 238.0
HKD1_k127_6978032_1 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000111 223.0
HKD1_k127_6978032_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000001073 213.0
HKD1_k127_6978032_3 TipAS antibiotic-recognition domain - - - 0.0000000000000000000000000000000000000006013 154.0
HKD1_k127_6978032_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000004955 140.0
HKD1_k127_6989606_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 424.0
HKD1_k127_6989606_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 404.0
HKD1_k127_6991198_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 316.0
HKD1_k127_6991198_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 310.0
HKD1_k127_6991198_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.000000000000000000000000000000005641 147.0
HKD1_k127_6993637_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 506.0
HKD1_k127_6993637_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
HKD1_k127_6993637_2 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 324.0
HKD1_k127_6993637_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 295.0
HKD1_k127_6993637_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
HKD1_k127_6993637_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000005754 187.0
HKD1_k127_6993637_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000006769 180.0
HKD1_k127_6993637_7 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000001493 161.0
HKD1_k127_6993637_8 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000004863 142.0
HKD1_k127_6993749_0 Bacterial protein of unknown function (DUF885) - - - 6.043e-213 677.0
HKD1_k127_6993749_1 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 466.0
HKD1_k127_6993749_2 nucleoside-diphosphate sugar epimerase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 424.0
HKD1_k127_6993749_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000006611 164.0
HKD1_k127_7005391_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 2.781e-316 974.0
HKD1_k127_7005391_1 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 508.0
HKD1_k127_7005391_2 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 372.0
HKD1_k127_7005391_3 spore germination K03605 - - 0.0000000000000000000000000000000000000000006611 164.0
HKD1_k127_7005391_4 - - - - 0.000000000000000000000000000000000000000001266 160.0
HKD1_k127_7005391_5 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0005311 42.0
HKD1_k127_7008646_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 379.0
HKD1_k127_7008646_1 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.000000000000000000000000000000000000006853 162.0
HKD1_k127_7008646_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000002294 139.0
HKD1_k127_7015911_0 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 489.0
HKD1_k127_7015911_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 401.0
HKD1_k127_7018759_0 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 340.0
HKD1_k127_7018759_1 Cytochrome c - - - 0.00000000000000000000000000000000000006612 153.0
HKD1_k127_7018759_2 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000000004538 95.0
HKD1_k127_7018759_3 helix_turn_helix, Lux Regulon K07684 - - 0.00000008162 63.0
HKD1_k127_7018759_4 antisigma factor binding - - - 0.00003753 54.0
HKD1_k127_7019806_0 Cysteine-rich domain K00113 - 1.1.5.3 7.682e-211 665.0
HKD1_k127_7019806_1 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 496.0
HKD1_k127_7019806_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007357 256.0
HKD1_k127_7019806_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000001956 228.0
HKD1_k127_7019806_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000004779 138.0
HKD1_k127_7019806_5 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000001884 109.0
HKD1_k127_7061253_0 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 468.0
HKD1_k127_7061253_1 -O-antigen K18814 - - 0.00002651 54.0
HKD1_k127_7076227_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000008392 231.0
HKD1_k127_7076227_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000001204 156.0
HKD1_k127_7076227_2 acetyltransferase - - - 0.00000000000000000000000000008282 121.0
HKD1_k127_7076650_0 valine-tRNA ligase activity K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 1.141e-311 977.0
HKD1_k127_7076650_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003146 282.0
HKD1_k127_7076650_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000499 222.0
HKD1_k127_7083250_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000001009 139.0
HKD1_k127_7083250_1 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000001531 115.0
HKD1_k127_7083250_2 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000002114 79.0
HKD1_k127_7083250_3 smart pdz dhr glgf K04691,K04771,K08070 GO:0008150,GO:0009266,GO:0009628,GO:0050896 1.3.1.74,3.4.21.107 0.0006536 51.0
HKD1_k127_7092038_0 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 604.0
HKD1_k127_7092038_1 - - - - 0.00000000003362 74.0
HKD1_k127_7092038_2 Prokaryotic N-terminal methylation motif K02458,K02671 - - 0.0004976 51.0
HKD1_k127_7097869_0 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 429.0
HKD1_k127_7097869_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000001505 69.0
HKD1_k127_7101361_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000005556 234.0
HKD1_k127_7101361_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000009805 97.0
HKD1_k127_7102610_0 PFAM TonB-dependent Receptor - - - 0.0000000000000000000000000000000000000000000000000003937 205.0
HKD1_k127_7102610_1 TonB dependent receptor - - - 0.000000000000000000000008739 115.0
HKD1_k127_7102610_2 Protein of unknown function (DUF2911) - - - 0.00000000000000006056 88.0
HKD1_k127_7104589_0 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 610.0
HKD1_k127_7104589_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 298.0
HKD1_k127_7123774_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 618.0
HKD1_k127_7123774_1 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 408.0
HKD1_k127_7128730_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 509.0
HKD1_k127_7128730_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 447.0
HKD1_k127_7128730_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 414.0
HKD1_k127_7128730_3 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 394.0
HKD1_k127_7128730_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 307.0
HKD1_k127_7128730_5 iron-sulfur cluster assembly K07400 - - 0.000000000000000000000000000002632 128.0
HKD1_k127_7129798_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 351.0
HKD1_k127_7129798_1 response regulator K07685 - - 0.0000000000000000000000000009868 117.0
HKD1_k127_7138280_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 395.0
HKD1_k127_7138280_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001397 64.0
HKD1_k127_7142519_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 319.0
HKD1_k127_7142519_1 PFAM glutaredoxin K18917 - 1.20.4.3 0.000000000002582 71.0
HKD1_k127_7142519_2 cAMP biosynthetic process K12132 - 2.7.11.1 0.00008678 55.0
HKD1_k127_714512_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 348.0
HKD1_k127_714512_1 AI-2E family transporter - - - 0.0000000000000000000000000000000015 144.0
HKD1_k127_7147146_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 344.0
HKD1_k127_7147146_1 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000001968 84.0
HKD1_k127_7149335_0 - - - - 0.00000000000000000000000000000000001451 143.0
HKD1_k127_7149335_1 Putative esterase - - - 0.000000004361 60.0
HKD1_k127_7151088_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 504.0
HKD1_k127_7151088_1 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000001575 195.0
HKD1_k127_7151088_2 Xanthine and CO dehydrogenases maturation factor XdhC CoxF K07402 - - 0.0000000000000000000005198 100.0
HKD1_k127_7162395_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 405.0
HKD1_k127_7162395_1 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 327.0
HKD1_k127_7162395_2 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
HKD1_k127_7162395_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000001398 201.0
HKD1_k127_7162395_4 YjbR - - - 0.00000000000000000003827 91.0
HKD1_k127_7162395_5 NUDIX domain - - - 0.000000000001207 75.0
HKD1_k127_7162395_6 aspartic-type endopeptidase activity K06985 - - 0.00003229 52.0
HKD1_k127_7175393_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 527.0
HKD1_k127_7175393_1 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000004341 150.0
HKD1_k127_7175393_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000007249 102.0
HKD1_k127_7175393_3 - - - - 0.00000000000000006616 87.0
HKD1_k127_7177533_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 473.0
HKD1_k127_7177533_1 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000006386 123.0
HKD1_k127_7187580_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 431.0
HKD1_k127_7187580_1 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 419.0
HKD1_k127_7187580_2 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 332.0
HKD1_k127_7187580_3 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 319.0
HKD1_k127_7187580_4 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000165 178.0
HKD1_k127_7187580_5 - - - - 0.00000000000000000000000000000000000000000006348 175.0
HKD1_k127_7187580_6 - - - - 0.0000000000000000000000000000000000000000001227 169.0
HKD1_k127_7187580_7 dehydratase - - - 0.00000000000000000006567 94.0
HKD1_k127_7187580_8 dehydratase - - - 0.0000000000000006317 83.0
HKD1_k127_7202247_0 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 346.0
HKD1_k127_7202247_1 Belongs to the glycosyltransferase 26 family K05946,K13660 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000003821 220.0
HKD1_k127_7202247_2 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000002038 59.0
HKD1_k127_7205910_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 503.0
HKD1_k127_7205910_1 YtkA-like - - - 0.0001781 50.0
HKD1_k127_7215654_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.582e-226 712.0
HKD1_k127_7215654_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000001741 168.0
HKD1_k127_7215654_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000004805 117.0
HKD1_k127_7215654_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000007033 68.0
HKD1_k127_7227946_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 324.0
HKD1_k127_7227946_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000001344 182.0
HKD1_k127_7228133_0 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
HKD1_k127_7228133_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000003926 173.0
HKD1_k127_7228133_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000001846 152.0
HKD1_k127_7237315_0 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 333.0
HKD1_k127_7237315_1 Methyltransferase domain K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 298.0
HKD1_k127_7237315_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 287.0
HKD1_k127_7237315_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000009868 189.0
HKD1_k127_7237315_4 - - - - 0.000000000000000000000000000005448 126.0
HKD1_k127_7237315_5 - - - - 0.0000000000001536 76.0
HKD1_k127_7270631_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 283.0
HKD1_k127_7270631_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000352 191.0
HKD1_k127_7270631_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000001643 195.0
HKD1_k127_7270631_3 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000000000004984 181.0
HKD1_k127_7272861_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 3.385e-199 636.0
HKD1_k127_7272861_1 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000008512 237.0
HKD1_k127_7272861_2 BMC - - - 0.0000000000000000000000000000000001751 134.0
HKD1_k127_7272861_3 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000002969 114.0
HKD1_k127_7272861_4 Domain of unknown function (DUF4349) - - - 0.00000000000000000004293 96.0
HKD1_k127_7289087_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 425.0
HKD1_k127_7289087_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000002588 81.0
HKD1_k127_7290067_0 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004679 241.0
HKD1_k127_7290067_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000007108 136.0
HKD1_k127_7290067_2 Domain of unknown function (DUF5117) - - - 0.00000007723 56.0
HKD1_k127_7296058_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 448.0
HKD1_k127_7296058_1 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 336.0
HKD1_k127_7296058_2 conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003033 282.0
HKD1_k127_7296058_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000002978 153.0
HKD1_k127_7296058_4 Smr domain - - - 0.0000000000000000000000000007829 118.0
HKD1_k127_7296058_6 PQQ-like domain - - - 0.0000000000000002008 85.0
HKD1_k127_7296058_7 Protein of unknown function (DUF1573) - - - 0.0002758 45.0
HKD1_k127_7297397_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 389.0
HKD1_k127_7297397_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000002649 244.0
HKD1_k127_7297397_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000004437 115.0
HKD1_k127_7302511_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 483.0
HKD1_k127_7302511_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000003627 168.0
HKD1_k127_7302511_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000004445 137.0
HKD1_k127_7303713_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000005064 260.0
HKD1_k127_7303713_1 D-glucuronyl C5-epimerase C-terminus - - - 0.00005241 55.0
HKD1_k127_7307172_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 448.0
HKD1_k127_7307172_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 354.0
HKD1_k127_7307172_2 efflux transmembrane transporter activity - - - 0.0004391 44.0
HKD1_k127_7312473_0 efflux transmembrane transporter activity K02004 - - 1.843e-230 738.0
HKD1_k127_7312473_1 efflux transmembrane transporter activity - - - 1.28e-213 690.0
HKD1_k127_7312473_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 478.0
HKD1_k127_7312473_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000051 255.0
HKD1_k127_7312473_4 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000075 241.0
HKD1_k127_7312473_5 efflux transmembrane transporter activity - - - 0.0000009973 51.0
HKD1_k127_7331456_0 Transcriptional regulator K06921 - - 2.939e-220 715.0
HKD1_k127_7331456_1 B12 binding domain - - - 0.000000000001583 68.0
HKD1_k127_7341487_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 476.0
HKD1_k127_7341487_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 414.0
HKD1_k127_7342898_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000007625 217.0
HKD1_k127_7342898_1 Gaf domain K03832 - - 0.0000000001418 74.0
HKD1_k127_7343109_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006267 268.0
HKD1_k127_7343109_1 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000003915 221.0
HKD1_k127_7343109_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000005014 194.0
HKD1_k127_7343109_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000004576 94.0
HKD1_k127_7343109_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000467 74.0
HKD1_k127_7343109_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000003419 79.0
HKD1_k127_7344367_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 385.0
HKD1_k127_7344367_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 337.0
HKD1_k127_7344367_10 Prokaryotic N-terminal methylation motif K02650 - - 0.0000003744 58.0
HKD1_k127_7344367_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 329.0
HKD1_k127_7344367_3 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 310.0
HKD1_k127_7344367_4 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000000000000000000000000000000001324 206.0
HKD1_k127_7344367_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000001798 164.0
HKD1_k127_7344367_6 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000001774 164.0
HKD1_k127_7344367_7 - - - - 0.00000000000000000000000001962 119.0
HKD1_k127_7344367_8 YhhN family - - - 0.00000000000000000001723 96.0
HKD1_k127_7344367_9 PFAM cyclic nucleotide-binding K10914 - - 0.000000000000518 72.0
HKD1_k127_7348783_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 398.0
HKD1_k127_7348783_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000003014 139.0
HKD1_k127_7348783_2 nuclear chromosome segregation - - - 0.000000000000000000000416 110.0
HKD1_k127_7351709_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 375.0
HKD1_k127_7351709_1 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000001545 148.0
HKD1_k127_7351709_2 Regulatory protein, FmdB family - - - 0.0000000000000000003958 89.0
HKD1_k127_735789_0 Protein kinase domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000151 200.0
HKD1_k127_735789_1 PilZ domain K02676 - - 0.000001879 56.0
HKD1_k127_735789_2 Sporulation related domain - - - 0.0006761 51.0
HKD1_k127_7361283_0 Glycosyl transferase family 21 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 316.0
HKD1_k127_7361283_1 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003755 239.0
HKD1_k127_7361283_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000001542 199.0
HKD1_k127_7361283_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000118 179.0
HKD1_k127_7361283_4 GtrA-like protein - - - 0.0000000000000000000001332 108.0
HKD1_k127_7366267_0 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005939 280.0
HKD1_k127_7366267_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000006047 257.0
HKD1_k127_7366267_2 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000001423 226.0
HKD1_k127_7366267_3 Putative transmembrane protein (PGPGW) - - - 0.00000000000005421 77.0
HKD1_k127_7369792_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 484.0
HKD1_k127_7369792_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006205 265.0
HKD1_k127_7370245_0 Peptidase M14, carboxypeptidase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 509.0
HKD1_k127_7370245_1 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000000000000000000000000000000004645 190.0
HKD1_k127_7370245_2 PFAM Calcineurin-like phosphoesterase K07099 - - 0.00000000000000000000000004138 111.0
HKD1_k127_7370245_3 Anti-sigma-K factor rskA - - - 0.000000000000002027 87.0
HKD1_k127_7376026_0 lipid A biosynthetic process K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000002041 265.0
HKD1_k127_7376026_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000001443 201.0
HKD1_k127_7376026_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000006595 116.0
HKD1_k127_7392981_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 421.0
HKD1_k127_7392981_1 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 280.0
HKD1_k127_7392981_2 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000001265 162.0
HKD1_k127_7392981_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000002702 146.0
HKD1_k127_7392981_4 GrpB protein - - - 0.0000000000000000000000000000000002097 141.0
HKD1_k127_7392981_5 Domain of unknown function (DU1801) - - - 0.000000000000000000000003024 106.0
HKD1_k127_7392981_6 Sigma-70 region 2 K03088 - - 0.0000000000000000387 84.0
HKD1_k127_7392981_7 - - - - 0.00004461 53.0
HKD1_k127_7396403_0 G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000001546 216.0
HKD1_k127_7396403_1 carbohydrate transport K02027 - - 0.0000000000000005404 82.0
HKD1_k127_739664_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 314.0
HKD1_k127_739664_1 HD domain - - - 0.00000000000000000000000000000000000000000000000001485 196.0
HKD1_k127_739664_2 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000003712 77.0
HKD1_k127_739664_3 antisigma factor binding - - - 0.000000003183 64.0
HKD1_k127_7399454_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004505 273.0
HKD1_k127_7399454_1 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000001366 145.0
HKD1_k127_7400846_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 386.0
HKD1_k127_7400846_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000573 246.0
HKD1_k127_7401438_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
HKD1_k127_7401438_1 - - - - 0.00000000000000000000000000000000000001628 153.0
HKD1_k127_7401438_2 Domain of unknown function (DUF4956) - - - 0.000000005076 68.0
HKD1_k127_740977_0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000001208 129.0
HKD1_k127_7410574_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 494.0
HKD1_k127_7410574_1 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000001201 166.0
HKD1_k127_7415990_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 331.0
HKD1_k127_7415990_1 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000006868 260.0
HKD1_k127_7415990_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001003 258.0
HKD1_k127_7415990_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000001151 213.0
HKD1_k127_7415990_4 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.000000000000000005424 84.0
HKD1_k127_7421901_0 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 493.0
HKD1_k127_7421901_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000007221 202.0
HKD1_k127_7421901_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000003005 129.0
HKD1_k127_7425946_0 PFAM beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 306.0
HKD1_k127_7425946_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002098 257.0
HKD1_k127_7425946_2 COG1228 Imidazolonepropionase and related - - - 0.0000000000000000000000000000000000000000001005 166.0
HKD1_k127_7443147_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.022e-298 926.0
HKD1_k127_7443147_1 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 592.0
HKD1_k127_7443147_2 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 324.0
HKD1_k127_7443147_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000002478 254.0
HKD1_k127_7443147_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
HKD1_k127_7443147_5 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
HKD1_k127_7443147_6 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000004341 107.0
HKD1_k127_7443147_7 Fic/DOC family K07341 - - 0.0000000000000000002808 92.0
HKD1_k127_7443147_9 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.000001784 58.0
HKD1_k127_7450032_0 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 540.0
HKD1_k127_7452349_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 540.0
HKD1_k127_7452349_1 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 507.0
HKD1_k127_7456421_0 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 346.0
HKD1_k127_7456421_1 - - - - 0.00000000000000000000001375 108.0
HKD1_k127_7457315_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 440.0
HKD1_k127_7457315_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000001289 259.0
HKD1_k127_7457315_2 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366 - 1.7.7.1 0.000000000000000000000000000000000001762 145.0
HKD1_k127_7477064_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 422.0
HKD1_k127_7477064_1 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 383.0
HKD1_k127_749126_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 5.511e-216 687.0
HKD1_k127_749126_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 370.0
HKD1_k127_749126_2 Tetratricopeptide repeat - - - 0.000000002804 66.0
HKD1_k127_7499534_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 507.0
HKD1_k127_7499534_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000003943 271.0
HKD1_k127_7499534_2 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.0001609 47.0
HKD1_k127_750627_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 506.0
HKD1_k127_750627_1 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
HKD1_k127_7520223_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000001029 135.0
HKD1_k127_7520223_1 von Willebrand factor, type A K07114 - - 0.00000001371 66.0
HKD1_k127_7530847_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 350.0
HKD1_k127_7530847_1 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002369 276.0
HKD1_k127_7542578_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000000003685 204.0
HKD1_k127_7546525_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 488.0
HKD1_k127_7546525_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 337.0
HKD1_k127_7547660_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 614.0
HKD1_k127_7547660_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 368.0
HKD1_k127_7547660_2 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000003128 250.0
HKD1_k127_7547660_3 NAD+ binding K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000001899 243.0
HKD1_k127_7548216_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 436.0
HKD1_k127_7548216_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000005341 225.0
HKD1_k127_7570636_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 619.0
HKD1_k127_7570636_1 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 513.0
HKD1_k127_7570636_2 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000000000003182 200.0
HKD1_k127_7570636_3 - - - - 0.000000000000000000000000000000000000000000002053 170.0
HKD1_k127_7570636_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000575 89.0
HKD1_k127_7570636_5 CoA binding domain - - - 0.0000000000002986 79.0
HKD1_k127_7573481_0 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 311.0
HKD1_k127_7573481_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004151 268.0
HKD1_k127_7573481_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000001318 216.0
HKD1_k127_7573481_3 Stage II sporulation protein K06381 - - 0.0000000000000000006171 87.0
HKD1_k127_7574784_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 374.0
HKD1_k127_7574784_1 - - - - 0.0000000000000000000000000004807 124.0
HKD1_k127_7579217_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 288.0
HKD1_k127_7579217_1 Ribosomal protein L19 K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000006214 159.0
HKD1_k127_7579217_2 Tetratricopeptide repeat - - - 0.000000000000005292 79.0
HKD1_k127_7593459_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 370.0
HKD1_k127_7593459_1 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 347.0
HKD1_k127_7593459_2 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
HKD1_k127_760556_0 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 308.0
HKD1_k127_760556_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006704 254.0
HKD1_k127_760556_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000005436 144.0
HKD1_k127_7650617_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 470.0
HKD1_k127_7650617_1 Zn peptidase - - - 0.000002417 53.0
HKD1_k127_7652371_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001271 248.0
HKD1_k127_7652371_1 PFAM Archaeal ATPase - - - 0.00000000000000000000003737 116.0
HKD1_k127_7652371_2 - K16923 - - 0.00000000009976 75.0
HKD1_k127_7656299_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 405.0
HKD1_k127_7656299_1 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 322.0
HKD1_k127_7656299_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 315.0
HKD1_k127_7656299_3 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 291.0
HKD1_k127_7656299_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003111 264.0
HKD1_k127_7656299_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000006283 232.0
HKD1_k127_7656299_6 NAD(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 0.00000002929 58.0
HKD1_k127_7663760_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001625 251.0
HKD1_k127_7663760_1 glycolate biosynthetic process - - - 0.0000000000000000000000000000000000002916 150.0
HKD1_k127_7663760_2 oxidoreductase activity - - - 0.000000000003411 72.0
HKD1_k127_7666181_0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 574.0
HKD1_k127_7666181_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000001688 153.0
HKD1_k127_7667925_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 387.0
HKD1_k127_7667925_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000000000000000001322 207.0
HKD1_k127_7667925_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000051 180.0
HKD1_k127_7667925_3 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000001027 63.0
HKD1_k127_7677891_0 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 447.0
HKD1_k127_7677891_1 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.0000000000000000000000005899 110.0
HKD1_k127_7679853_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000735 204.0
HKD1_k127_7679853_1 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000971 190.0
HKD1_k127_7684350_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 601.0
HKD1_k127_7684350_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 329.0
HKD1_k127_7684350_2 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000001702 232.0
HKD1_k127_7684350_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000355 184.0
HKD1_k127_7684350_4 Protein tyrosine kinase - - - 0.000158 45.0
HKD1_k127_7698512_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000003003 157.0
HKD1_k127_7698512_1 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000001096 130.0
HKD1_k127_7698512_2 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000004895 79.0
HKD1_k127_7698512_3 ompA family - - - 0.00000005642 63.0
HKD1_k127_7699142_0 LUD domain K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 476.0
HKD1_k127_7699142_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 286.0
HKD1_k127_7699142_2 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000001814 178.0
HKD1_k127_7699142_3 LUD domain K00782 - - 0.0000000000000000000000000007078 123.0
HKD1_k127_7699142_5 - - - - 0.0000000002787 67.0
HKD1_k127_7705214_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000001162 208.0
HKD1_k127_7705214_1 Tetratricopeptide repeat - - - 0.000000000000000000001743 108.0
HKD1_k127_7709998_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 355.0
HKD1_k127_7709998_1 Domain of unknown function (DUF4131) K02238 - - 0.000000000000000000000004666 116.0
HKD1_k127_7721367_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 423.0
HKD1_k127_7721367_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 321.0
HKD1_k127_7722397_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 614.0
HKD1_k127_7722397_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 430.0
HKD1_k127_7722936_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 5.231e-215 676.0
HKD1_k127_7722936_1 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 604.0
HKD1_k127_7722936_2 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 338.0
HKD1_k127_7734977_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 584.0
HKD1_k127_7734977_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 312.0
HKD1_k127_7734977_2 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000003728 240.0
HKD1_k127_7739659_0 Protein of unknown function (DUF3142) - - - 0.0000000000005777 82.0
HKD1_k127_7741335_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000004849 130.0
HKD1_k127_7741335_1 PFAM glycosyl transferase family 39 - - - 0.0000002628 55.0
HKD1_k127_7741335_2 FHA domain - - - 0.00008611 53.0
HKD1_k127_7741335_3 peptidyl-tyrosine sulfation - - - 0.0001057 51.0
HKD1_k127_7754056_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1425.0
HKD1_k127_7754056_1 nucleotidyltransferase activity K01154,K07076 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 435.0
HKD1_k127_7754056_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 361.0
HKD1_k127_7760166_0 efflux transmembrane transporter activity K02004 - - 2.906e-222 715.0
HKD1_k127_7760166_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 580.0
HKD1_k127_7760166_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 332.0
HKD1_k127_7760166_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003648 273.0
HKD1_k127_7760166_4 FtsX-like permease family - - - 0.0000000000000000000000002271 108.0
HKD1_k127_7770169_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 592.0
HKD1_k127_7770169_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000003993 222.0
HKD1_k127_7770169_2 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000001901 135.0
HKD1_k127_7770169_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000003238 128.0
HKD1_k127_7773325_0 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 455.0
HKD1_k127_7773325_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 333.0
HKD1_k127_7776092_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 488.0
HKD1_k127_7776092_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 384.0
HKD1_k127_7776092_2 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000005991 216.0
HKD1_k127_7776092_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000002886 75.0
HKD1_k127_7776092_4 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0009765 48.0
HKD1_k127_7776851_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 386.0
HKD1_k127_7776851_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000009011 140.0
HKD1_k127_7776851_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000001358 56.0
HKD1_k127_7793550_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 427.0
HKD1_k127_7793550_1 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 250.0
HKD1_k127_7793550_2 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000007068 198.0
HKD1_k127_7797843_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000003204 201.0
HKD1_k127_7797843_1 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.000000000000000000000000003732 120.0
HKD1_k127_7799702_0 Sodium:solute symporter family - - - 3.684e-272 850.0
HKD1_k127_7799702_1 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 325.0
HKD1_k127_7800784_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 496.0
HKD1_k127_7800784_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000003083 65.0
HKD1_k127_7800784_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000001546 61.0
HKD1_k127_7801613_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 418.0
HKD1_k127_7801613_1 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 264.0
HKD1_k127_7801613_2 Alpha/beta hydrolase family - - - 0.00009953 48.0
HKD1_k127_7801613_3 Acid phosphatase homologues - - - 0.0009203 49.0
HKD1_k127_7810902_0 Dihydroorotate dehydrogenase K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 357.0
HKD1_k127_7810902_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000007244 196.0
HKD1_k127_7810902_2 Oxidoreductase NAD-binding domain K02823 - - 0.00000000000000000000000000000000000000000007875 172.0
HKD1_k127_7810902_3 CS domain K13993 - - 0.00000000000000000000000000000000001273 141.0
HKD1_k127_7810902_4 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000001018 137.0
HKD1_k127_7810902_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000001373 140.0
HKD1_k127_7810902_6 Polymer-forming cytoskeletal - - - 0.00000000000000000004094 94.0
HKD1_k127_7816179_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002843 274.0
HKD1_k127_7816179_1 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000000001325 211.0
HKD1_k127_7816179_2 C4-type zinc ribbon domain K07164 - - 0.0000000000000000002777 97.0
HKD1_k127_7835858_0 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000002148 160.0
HKD1_k127_7849919_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 578.0
HKD1_k127_7849919_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 434.0
HKD1_k127_7849919_2 COG1012 NAD-dependent aldehyde - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 433.0
HKD1_k127_7849919_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 345.0
HKD1_k127_7849919_4 - - - - 0.000000002358 65.0
HKD1_k127_786164_0 SMART Elongator protein 3 MiaB NifB - - - 1.154e-216 683.0
HKD1_k127_786164_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001513 256.0
HKD1_k127_786164_2 transcriptional regulator - - - 0.000000000001962 70.0
HKD1_k127_786164_3 beta-propeller repeat - - - 0.000009944 49.0
HKD1_k127_7865846_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 507.0
HKD1_k127_7865846_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000002133 186.0
HKD1_k127_7865969_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 316.0
HKD1_k127_7865969_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0002316 45.0
HKD1_k127_7876174_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 492.0
HKD1_k127_7876174_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 469.0
HKD1_k127_7876174_2 Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 370.0
HKD1_k127_7876174_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000003181 133.0
HKD1_k127_7876174_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000002899 61.0
HKD1_k127_7876174_5 Domain of unknown function (DU1801) - - - 0.00000002801 60.0
HKD1_k127_7880524_0 Glycosyl transferase family 21 K11936 - - 0.0 1018.0
HKD1_k127_7884707_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.737e-220 690.0
HKD1_k127_7884707_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000001305 209.0
HKD1_k127_7884707_2 - - - - 0.000000000000000000000000000000000000000000000001922 181.0
HKD1_k127_7884707_3 - - - - 0.000000000000000000000000000000000000000000000235 176.0
HKD1_k127_7894819_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 447.0
HKD1_k127_7894819_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000003561 222.0
HKD1_k127_7894928_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 350.0
HKD1_k127_7894928_1 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000003049 194.0
HKD1_k127_7894928_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000009152 167.0
HKD1_k127_7894928_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000003962 141.0
HKD1_k127_7894928_4 - K07018 - - 0.000000000000000000000000000000000002746 142.0
HKD1_k127_7894928_5 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000001019 138.0
HKD1_k127_7894928_6 PA14 domain - - - 0.00000004669 65.0
HKD1_k127_7900511_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 500.0
HKD1_k127_7900511_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000001156 109.0
HKD1_k127_7901651_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 290.0
HKD1_k127_7901651_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000008886 161.0
HKD1_k127_7901651_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000001434 129.0
HKD1_k127_7904086_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 526.0
HKD1_k127_7904086_1 UvrD/REP helicase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 327.0
HKD1_k127_7904086_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000008847 101.0
HKD1_k127_7904086_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000005502 68.0
HKD1_k127_7904086_4 ATP-dependent helicase deoxyribonuclease subunit B K16899 - 3.6.4.12 0.00003993 55.0
HKD1_k127_7904086_5 addiction module component - - - 0.0005045 47.0
HKD1_k127_7914824_0 TIGRFAM glutamine synthetase, type I K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 593.0
HKD1_k127_7914824_1 sequence-specific DNA binding K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 402.0
HKD1_k127_7914824_2 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000002878 240.0
HKD1_k127_7914824_3 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000001057 175.0
HKD1_k127_7922921_0 Sugar isomerase, AgaS family K02082 - - 0.0000000000000000000000000000000000000001416 165.0
HKD1_k127_7922921_1 LysR substrate binding domain - - - 0.000000000000000000006441 97.0
HKD1_k127_7922921_2 N-acetylglucosamine kinase activity - - - 0.0000007305 54.0
HKD1_k127_7926820_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 367.0
HKD1_k127_7926820_1 AAA domain - - - 0.0000000000000000000000000000000711 137.0
HKD1_k127_7926820_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000004479 74.0
HKD1_k127_7939972_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 569.0
HKD1_k127_794365_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 431.0
HKD1_k127_794365_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000001016 73.0
HKD1_k127_7944097_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 520.0
HKD1_k127_7944097_1 Protein kinase domain K12132 - 2.7.11.1 0.000000002845 59.0
HKD1_k127_7952668_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.895e-273 861.0
HKD1_k127_7952668_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
HKD1_k127_7952668_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000006446 95.0
HKD1_k127_7954983_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 421.0
HKD1_k127_7968065_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 393.0
HKD1_k127_7968065_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000007281 186.0
HKD1_k127_7971230_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 334.0
HKD1_k127_7971230_1 Belongs to the peptidase S8 family - - - 0.000000000000000001941 96.0
HKD1_k127_7971230_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001432 78.0
HKD1_k127_7991157_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 517.0
HKD1_k127_7991687_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1254.0
HKD1_k127_7991687_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 402.0
HKD1_k127_7991687_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 376.0
HKD1_k127_7991687_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000003591 69.0
HKD1_k127_8005535_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009794 275.0
HKD1_k127_8005535_1 glycosyl transferase family 2 - - - 0.00000000000000000000000000004034 128.0
HKD1_k127_8005535_2 Glycosyltransferase like family 2 - - - 0.000007049 49.0
HKD1_k127_8006608_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 381.0
HKD1_k127_8006608_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 331.0
HKD1_k127_8006608_2 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 308.0
HKD1_k127_8006608_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001822 257.0
HKD1_k127_8030446_0 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 320.0
HKD1_k127_8035832_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.599e-237 743.0
HKD1_k127_8035832_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 544.0
HKD1_k127_8035832_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 312.0
HKD1_k127_8035832_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 308.0
HKD1_k127_8035832_4 ParB-like nuclease domain K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000003136 215.0
HKD1_k127_8035832_5 MarR family transcriptional regulator - - - 0.0000000000000000000000000000000000000518 147.0
HKD1_k127_8035832_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000001532 98.0
HKD1_k127_820236_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001199 275.0
HKD1_k127_820236_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000001477 229.0
HKD1_k127_820236_2 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000001796 216.0
HKD1_k127_822149_0 Tricorn protease homolog - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 356.0
HKD1_k127_822149_1 Aldehyde dehydrogenase family K22187 - - 0.00000000000000001875 93.0
HKD1_k127_829691_0 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001508 254.0
HKD1_k127_829691_1 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000009121 215.0
HKD1_k127_829691_2 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000001806 74.0
HKD1_k127_846848_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003491 261.0
HKD1_k127_846848_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001749 243.0
HKD1_k127_846848_2 abc transporter atp-binding protein K01990 - - 0.00000377 49.0
HKD1_k127_848403_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.281e-298 926.0
HKD1_k127_848403_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 289.0
HKD1_k127_848403_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000009881 50.0
HKD1_k127_853419_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 434.0
HKD1_k127_853862_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000412 218.0
HKD1_k127_853862_1 YbbR-like protein - - - 0.0000000000792 72.0
HKD1_k127_858434_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 303.0
HKD1_k127_858434_1 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000174 93.0
HKD1_k127_859923_0 tail specific protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 317.0
HKD1_k127_859923_1 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.0000000009356 60.0
HKD1_k127_863017_0 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 419.0
HKD1_k127_863017_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 398.0
HKD1_k127_863017_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 360.0
HKD1_k127_863017_3 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000009161 199.0
HKD1_k127_868731_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 576.0
HKD1_k127_868731_1 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 390.0
HKD1_k127_868731_2 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 315.0
HKD1_k127_871186_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 367.0
HKD1_k127_871186_1 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002031 282.0
HKD1_k127_871186_2 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000001485 217.0
HKD1_k127_88057_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 592.0
HKD1_k127_88057_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 372.0
HKD1_k127_88057_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 322.0
HKD1_k127_88057_3 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 250.0
HKD1_k127_891727_0 pfam php K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 384.0
HKD1_k127_891727_3 Universal stress protein K06149 - - 0.00000000000005711 74.0
HKD1_k127_897476_0 general stress protein - - - 0.00000000000000006696 85.0
HKD1_k127_900100_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 599.0
HKD1_k127_900100_1 Belongs to the ATCase OTCase family K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 334.0
HKD1_k127_900100_2 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 314.0
HKD1_k127_900100_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008218 286.0
HKD1_k127_900100_4 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008628 282.0
HKD1_k127_900100_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
HKD1_k127_900100_6 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000995 78.0
HKD1_k127_902475_0 Large extracellular alpha-helical protein K06894 - - 0.0 1198.0
HKD1_k127_902475_1 Zinc carboxypeptidase - - - 0.0000000000000000000000009992 105.0
HKD1_k127_902684_0 - - - - 0.0000000000000000000001817 111.0
HKD1_k127_902684_1 PBS lyase HEAT-like repeat K05384 - - 0.00006221 53.0
HKD1_k127_905052_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 446.0
HKD1_k127_905052_1 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000002126 173.0
HKD1_k127_921918_0 Ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 508.0
HKD1_k127_921918_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 425.0
HKD1_k127_924451_0 ABC transporter K01990 - - 0.00000000000000000000000000003754 132.0
HKD1_k127_924451_1 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000487 103.0
HKD1_k127_930129_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 1.723e-216 682.0
HKD1_k127_930129_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001062 286.0
HKD1_k127_932021_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 1.466e-221 702.0
HKD1_k127_932021_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000001615 169.0
HKD1_k127_933848_0 PFAM multi antimicrobial extrusion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 535.0
HKD1_k127_933848_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 483.0
HKD1_k127_933848_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 328.0
HKD1_k127_933848_3 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000602 289.0
HKD1_k127_933848_4 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000001475 182.0
HKD1_k127_941737_0 efflux transmembrane transporter activity - - - 9.715e-198 644.0
HKD1_k127_941737_1 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 379.0
HKD1_k127_941737_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001056 260.0
HKD1_k127_946759_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 293.0
HKD1_k127_946759_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002888 264.0
HKD1_k127_9477_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 2.452e-313 969.0
HKD1_k127_967957_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.991e-245 767.0
HKD1_k127_967957_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 438.0
HKD1_k127_967957_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008636 269.0
HKD1_k127_967957_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000005575 143.0
HKD1_k127_967957_4 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000001242 111.0
HKD1_k127_968542_0 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 507.0
HKD1_k127_968542_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000008756 78.0
HKD1_k127_968542_2 - - - - 0.000000000000001142 80.0
HKD1_k127_973117_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 610.0
HKD1_k127_973117_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 594.0
HKD1_k127_973117_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 302.0
HKD1_k127_973117_3 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 262.0
HKD1_k127_973117_4 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000000001562 218.0
HKD1_k127_973117_5 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000006434 225.0
HKD1_k127_973117_7 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000000003449 184.0
HKD1_k127_975779_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 362.0
HKD1_k127_975779_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 353.0
HKD1_k127_975779_2 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000001512 213.0
HKD1_k127_975779_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000008043 84.0
HKD1_k127_979436_0 Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 409.0
HKD1_k127_979436_1 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 416.0
HKD1_k127_979436_2 Tyrosine phosphatase family - - - 0.0000000000004319 74.0
HKD1_k127_979439_0 Cytochrome c554 and c-prime - - - 7.279e-315 991.0
HKD1_k127_979439_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 521.0
HKD1_k127_979439_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 451.0
HKD1_k127_979852_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 599.0
HKD1_k127_994218_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000009402 183.0
HKD1_k127_994218_1 repeat-containing protein - - - 0.00000000001338 76.0