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Overview

ID MAG01773
Name HKD2_bin.12
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhizobiales
Family Xanthobacteraceae
Genus Pseudolabrys
Species
Assembly information
Completeness (%) 67.57
Contamination (%) 2.64
GC content (%) 64.0
N50 (bp) 9,234
Genome size (bp) 2,407,863

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2582

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10028108_0 Serine threonine protein kinase - - - 1.412e-223 701.0
HKD2_k127_10028108_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 344.0
HKD2_k127_10028108_2 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000149 79.0
HKD2_k127_10068914_0 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 398.0
HKD2_k127_10068914_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 383.0
HKD2_k127_10068914_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 323.0
HKD2_k127_10068914_3 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 304.0
HKD2_k127_10068914_4 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000003244 254.0
HKD2_k127_10068914_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000006837 147.0
HKD2_k127_10095692_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 374.0
HKD2_k127_10095692_1 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 338.0
HKD2_k127_10095692_2 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 332.0
HKD2_k127_10095692_3 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006215 277.0
HKD2_k127_10095692_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000633 144.0
HKD2_k127_10095912_0 ATPase (P-type) K01535 - 3.6.3.6 0.0 1201.0
HKD2_k127_10095912_1 Homospermidine synthase K00808 - 2.5.1.44 1.209e-267 831.0
HKD2_k127_10095912_2 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 578.0
HKD2_k127_10095912_3 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 411.0
HKD2_k127_10095912_4 ErfK YbiS YcfS YnhG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001101 249.0
HKD2_k127_10095912_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000002838 104.0
HKD2_k127_10095912_6 - - - - 0.00000000000000000000002186 100.0
HKD2_k127_1036579_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 3.225e-308 950.0
HKD2_k127_1036579_1 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 528.0
HKD2_k127_1036579_10 - - - - 0.0000000000000000000000000000000000006132 156.0
HKD2_k127_1036579_11 GYD domain - - - 0.0000000000000000000000000000000005805 134.0
HKD2_k127_1036579_12 Transposase and inactivated derivatives, IS5 family K07481 - - 0.000000000000000000000000000000000667 133.0
HKD2_k127_1036579_13 antibiotic catabolic process - - - 0.00000000000000000000000000124 123.0
HKD2_k127_1036579_14 Thioredoxin domain - - - 0.0000000000000000000000187 110.0
HKD2_k127_1036579_15 - - - - 0.00000000000000000000002578 104.0
HKD2_k127_1036579_16 - - - - 0.00000000000000000006367 93.0
HKD2_k127_1036579_17 MaoC like domain - - - 0.000000000000001175 77.0
HKD2_k127_1036579_18 Ribbon-helix-helix domain - - - 0.000000000000001567 81.0
HKD2_k127_1036579_19 - - - - 0.00000005855 57.0
HKD2_k127_1036579_2 OpgC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 376.0
HKD2_k127_1036579_20 - - - - 0.0008077 46.0
HKD2_k127_1036579_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 329.0
HKD2_k127_1036579_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 316.0
HKD2_k127_1036579_5 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000211 194.0
HKD2_k127_1036579_6 Cupin domain - - - 0.00000000000000000000000000000000000000000001851 166.0
HKD2_k127_1036579_7 regulatory protein, arsR K03892 - - 0.0000000000000000000000000000000000000000007241 161.0
HKD2_k127_1036579_8 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000000000000003172 162.0
HKD2_k127_1036579_9 Putative mono-oxygenase ydhR - - - 0.00000000000000000000000000000000000000007863 153.0
HKD2_k127_105528_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 407.0
HKD2_k127_105528_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 302.0
HKD2_k127_105528_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001278 273.0
HKD2_k127_105528_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008104 233.0
HKD2_k127_1058129_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 364.0
HKD2_k127_1058129_1 LppC putative lipoprotein - - - 0.000000000000000000000000000000003507 132.0
HKD2_k127_1058129_2 Belongs to the UPF0102 family K07460 - - 0.0000000000002325 72.0
HKD2_k127_10610_0 Cobalamin biosynthesis protein CobT VWA domain K09883 - 6.6.1.2 1.175e-299 929.0
HKD2_k127_10610_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 2.844e-200 625.0
HKD2_k127_10610_2 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 589.0
HKD2_k127_10610_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 507.0
HKD2_k127_10610_4 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 339.0
HKD2_k127_10610_5 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006708 256.0
HKD2_k127_10610_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000002527 214.0
HKD2_k127_10610_7 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.00000000000000000000000000000000000007659 145.0
HKD2_k127_10610_8 structural constituent of ribosome K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000003604 141.0
HKD2_k127_10610_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000006283 134.0
HKD2_k127_1158187_0 COG0339 Zn-dependent oligopeptidases K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 2.339e-294 917.0
HKD2_k127_1158187_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.753e-246 774.0
HKD2_k127_1158187_10 - - - - 0.000000000000000000000001732 105.0
HKD2_k127_1158187_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.706e-238 748.0
HKD2_k127_1158187_3 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 429.0
HKD2_k127_1158187_4 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 372.0
HKD2_k127_1158187_5 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 361.0
HKD2_k127_1158187_6 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 333.0
HKD2_k127_1158187_7 Protein of unknown function (DUF1007) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 241.0
HKD2_k127_1158187_8 Nitrile hydratase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000082 220.0
HKD2_k127_1158187_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000002672 171.0
HKD2_k127_1198926_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 462.0
HKD2_k127_1198926_1 Haloacid dehalogenase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 349.0
HKD2_k127_1198926_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003199 220.0
HKD2_k127_1198926_3 - - - - 0.000000001757 61.0
HKD2_k127_121510_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1311.0
HKD2_k127_121510_1 Voltage gated chloride channel K03281 - - 3.306e-217 689.0
HKD2_k127_121510_10 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000003264 109.0
HKD2_k127_121510_11 - - - - 0.000000000000000000002763 97.0
HKD2_k127_121510_12 Protein of unknown function (DUF1328) - - - 0.000000008634 58.0
HKD2_k127_121510_13 Diguanylate cyclase - - - 0.0000004591 56.0
HKD2_k127_121510_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 551.0
HKD2_k127_121510_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 491.0
HKD2_k127_121510_4 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 372.0
HKD2_k127_121510_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 362.0
HKD2_k127_121510_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 284.0
HKD2_k127_121510_7 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000002556 248.0
HKD2_k127_121510_8 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000509 137.0
HKD2_k127_121510_9 EAL domain - - - 0.0000000000000000000000000000000555 132.0
HKD2_k127_1248249_0 FtsX-like permease family K02004 - - 0.0 1043.0
HKD2_k127_1248249_1 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 506.0
HKD2_k127_1248249_2 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 345.0
HKD2_k127_1248249_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000002822 264.0
HKD2_k127_1248249_4 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000005078 248.0
HKD2_k127_1248249_5 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000003519 231.0
HKD2_k127_1248249_6 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000002229 215.0
HKD2_k127_1248249_7 Protein of unknown function (DUF1003) - - - 0.000000002291 59.0
HKD2_k127_1254592_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.11e-237 745.0
HKD2_k127_1254592_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 7.054e-231 722.0
HKD2_k127_1254592_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 593.0
HKD2_k127_1254592_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 476.0
HKD2_k127_1254592_4 Colicin V production protein K03558 - - 0.000000000000001741 78.0
HKD2_k127_1259876_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 436.0
HKD2_k127_1259876_1 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 440.0
HKD2_k127_1259876_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 366.0
HKD2_k127_1259876_3 Domain of unknown function (DUF1330) - - - 0.000000000000000000000002731 104.0
HKD2_k127_1259876_4 - - - - 0.000000000000000000001134 95.0
HKD2_k127_1259876_5 - - - - 0.000000000009057 67.0
HKD2_k127_1275966_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 9.118e-276 854.0
HKD2_k127_1275966_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 8.368e-210 657.0
HKD2_k127_1275966_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 396.0
HKD2_k127_1275966_3 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000000000000001398 189.0
HKD2_k127_1275966_4 Opacity family porin protein - - - 0.00000000000000000000000000000000000001628 153.0
HKD2_k127_1275966_5 Transposase - - - 0.00000000000000000000000006358 112.0
HKD2_k127_1275966_6 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000001545 103.0
HKD2_k127_1275966_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000001939 64.0
HKD2_k127_1294437_0 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 574.0
HKD2_k127_1294437_1 Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 584.0
HKD2_k127_1294437_10 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000001347 236.0
HKD2_k127_1294437_11 - - - - 0.000000000000000000000000000000000000000000000000000003724 196.0
HKD2_k127_1294437_12 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000008801 199.0
HKD2_k127_1294437_13 of the double-stranded beta helix - - - 0.00000000000000000000000000000000000000000000000000004833 193.0
HKD2_k127_1294437_14 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000005474 196.0
HKD2_k127_1294437_15 OmpA family - - - 0.00000000000000000000000000000000008918 146.0
HKD2_k127_1294437_16 TupA-like ATPgrasp - - - 0.0000000000000000000000000000000001542 139.0
HKD2_k127_1294437_17 DoxX K15977 - - 0.00000000000000000000000742 106.0
HKD2_k127_1294437_18 Glycosyl transferase, family 2 - - - 0.000004848 55.0
HKD2_k127_1294437_2 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 467.0
HKD2_k127_1294437_3 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 378.0
HKD2_k127_1294437_4 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 359.0
HKD2_k127_1294437_5 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 319.0
HKD2_k127_1294437_6 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 312.0
HKD2_k127_1294437_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 302.0
HKD2_k127_1294437_8 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 287.0
HKD2_k127_1294437_9 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005665 263.0
HKD2_k127_1294854_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.191e-261 811.0
HKD2_k127_1294854_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000002309 123.0
HKD2_k127_1294854_2 SnoaL-like domain - - - 0.000000000000000000007593 96.0
HKD2_k127_1294854_3 DDE superfamily endonuclease K07494 - - 0.000001919 51.0
HKD2_k127_1295761_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.58e-268 831.0
HKD2_k127_1295761_1 ABC transporter K02471 - - 3.291e-242 761.0
HKD2_k127_1295761_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 371.0
HKD2_k127_1295761_11 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 353.0
HKD2_k127_1295761_12 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000001944 185.0
HKD2_k127_1295761_2 Receptor family ligand binding region K01999 - - 2.651e-217 680.0
HKD2_k127_1295761_3 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 597.0
HKD2_k127_1295761_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 565.0
HKD2_k127_1295761_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 553.0
HKD2_k127_1295761_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 487.0
HKD2_k127_1295761_7 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 469.0
HKD2_k127_1295761_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 388.0
HKD2_k127_1295761_9 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 379.0
HKD2_k127_1303585_0 FAD linked oxidases, C-terminal domain - - - 0.0 1359.0
HKD2_k127_1303585_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 610.0
HKD2_k127_1303585_2 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 465.0
HKD2_k127_1303585_3 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 447.0
HKD2_k127_1303585_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000002844 184.0
HKD2_k127_1303658_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 467.0
HKD2_k127_1303658_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 436.0
HKD2_k127_1303658_2 MFS/sugar transport protein K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 414.0
HKD2_k127_1303658_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 377.0
HKD2_k127_1303658_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 365.0
HKD2_k127_1303658_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 339.0
HKD2_k127_1303658_6 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
HKD2_k127_1303658_7 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
HKD2_k127_1303658_8 MarR family K06075 - - 0.0000000000000000000000000000000000000000002729 163.0
HKD2_k127_1303658_9 EamA-like transporter family - - - 0.0000000000000000000000002278 108.0
HKD2_k127_1319183_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 405.0
HKD2_k127_1319183_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 342.0
HKD2_k127_1319183_10 Transcriptional regulator - - - 0.000002057 49.0
HKD2_k127_1319183_2 - - - - 0.00000000000000000000000000000000000000000000002081 180.0
HKD2_k127_1319183_3 GYD domain - - - 0.00000000000000000000000000000005825 128.0
HKD2_k127_1319183_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000005257 129.0
HKD2_k127_1319183_5 - - - - 0.00000000000000000191 91.0
HKD2_k127_1319183_7 Tetratricopeptide repeat - - - 0.00000000000002747 78.0
HKD2_k127_1319183_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000001835 55.0
HKD2_k127_1319183_9 - - - - 0.0000001014 55.0
HKD2_k127_132468_0 B12 binding domain K14447 - 5.4.99.63 0.0 1021.0
HKD2_k127_132468_1 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 1.418e-267 833.0
HKD2_k127_132468_10 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000000000000000000000003586 189.0
HKD2_k127_132468_11 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000002567 131.0
HKD2_k127_132468_12 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000003379 122.0
HKD2_k127_132468_13 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000007325 110.0
HKD2_k127_132468_14 - - - - 0.000000003175 61.0
HKD2_k127_132468_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0002986 49.0
HKD2_k127_132468_2 Alcohol dehydrogenase GroES-like domain K00001,K14446 - 1.1.1.1,1.3.1.85 1.41e-249 773.0
HKD2_k127_132468_3 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 428.0
HKD2_k127_132468_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 364.0
HKD2_k127_132468_5 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
HKD2_k127_132468_6 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004211 255.0
HKD2_k127_132468_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000004823 220.0
HKD2_k127_132468_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000007301 209.0
HKD2_k127_132468_9 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000001881 194.0
HKD2_k127_1338623_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 535.0
HKD2_k127_1338623_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000002441 219.0
HKD2_k127_1338623_2 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000004224 202.0
HKD2_k127_134827_0 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 8.382e-203 640.0
HKD2_k127_134827_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 520.0
HKD2_k127_134827_10 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.000000000000000000000000000114 117.0
HKD2_k127_134827_2 Peptidase family U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 465.0
HKD2_k127_134827_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 323.0
HKD2_k127_134827_4 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 327.0
HKD2_k127_134827_5 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 263.0
HKD2_k127_134827_6 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002293 248.0
HKD2_k127_134827_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000001538 187.0
HKD2_k127_134827_8 lipid carrier protein - - - 0.000000000000000000000000000000006712 134.0
HKD2_k127_134827_9 - - - - 0.00000000000000000000000000005574 124.0
HKD2_k127_136239_0 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0 1327.0
HKD2_k127_136239_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 609.0
HKD2_k127_136239_10 S4 domain K04762 - - 0.0000000000000000000000000001726 117.0
HKD2_k127_136239_11 membrane - - - 0.00000000000000000000000001748 113.0
HKD2_k127_136239_12 DDE superfamily endonuclease - - - 0.000000000000001689 75.0
HKD2_k127_136239_13 Tetratricopeptide repeat - - - 0.00000000002301 69.0
HKD2_k127_136239_14 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000002645 63.0
HKD2_k127_136239_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 404.0
HKD2_k127_136239_3 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 317.0
HKD2_k127_136239_4 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 302.0
HKD2_k127_136239_5 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 292.0
HKD2_k127_136239_6 TIGRFAM yecA family protein K07039 - - 0.000000000000000000000000000000000000000000000000000000000000000001442 234.0
HKD2_k127_136239_7 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000004342 219.0
HKD2_k127_136239_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000009141 154.0
HKD2_k127_136239_9 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000001452 155.0
HKD2_k127_1366445_0 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 473.0
HKD2_k127_1366445_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000006176 163.0
HKD2_k127_1367732_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.329e-249 775.0
HKD2_k127_1367732_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 599.0
HKD2_k127_1367732_2 Belongs to the D-alanine--D-alanine ligase family K00075,K01921 - 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 468.0
HKD2_k127_1367732_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 433.0
HKD2_k127_1367732_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 429.0
HKD2_k127_1367732_5 Essential cell division protein K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001048 265.0
HKD2_k127_1367732_6 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000006579 147.0
HKD2_k127_1367732_7 Domain of unknown function (DUF1902) - - - 0.00000000000000000000000000000000002677 138.0
HKD2_k127_1367732_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000005857 104.0
HKD2_k127_1372265_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.856e-201 629.0
HKD2_k127_1372265_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 508.0
HKD2_k127_1372265_2 FAD linked K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 412.0
HKD2_k127_1391454_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1684.0
HKD2_k127_1391454_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 5.9e-279 872.0
HKD2_k127_1391454_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 1.063e-222 694.0
HKD2_k127_1391454_3 Catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004781 282.0
HKD2_k127_1391454_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001799 220.0
HKD2_k127_1391454_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000007616 215.0
HKD2_k127_1391454_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000003325 68.0
HKD2_k127_1405801_0 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 6.25e-270 842.0
HKD2_k127_1405801_1 Peptidase dimerisation domain K01436 - - 1.323e-201 639.0
HKD2_k127_1405801_10 - - - - 0.00000000000000000000000171 114.0
HKD2_k127_1405801_11 Fe-S metabolism associated domain K02426 - - 0.0000000000000000536 81.0
HKD2_k127_1405801_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 3.883e-200 637.0
HKD2_k127_1405801_3 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 494.0
HKD2_k127_1405801_4 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 459.0
HKD2_k127_1405801_5 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 413.0
HKD2_k127_1405801_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 390.0
HKD2_k127_1405801_7 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 363.0
HKD2_k127_1405801_8 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000295 278.0
HKD2_k127_1405801_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000003639 222.0
HKD2_k127_1419436_0 benzoate-CoA ligase K04105 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 460.0
HKD2_k127_1419436_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04109,K11178 - 1.17.1.4,1.3.7.9 0.000000000000000000000000000000000000000000000000000008482 195.0
HKD2_k127_1424116_0 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000001047 191.0
HKD2_k127_1424116_1 Predicted permease - - - 0.0000000000000000000000000000000000000000000000003055 188.0
HKD2_k127_1424116_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000002371 155.0
HKD2_k127_1427852_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003006 267.0
HKD2_k127_1427852_1 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000008064 214.0
HKD2_k127_1427852_2 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000004469 183.0
HKD2_k127_1427852_3 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000003748 132.0
HKD2_k127_143309_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 509.0
HKD2_k127_143309_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 296.0
HKD2_k127_143309_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000004058 200.0
HKD2_k127_143309_3 Putative cyclase - - - 0.0000000000000000000000000000004607 123.0
HKD2_k127_1433139_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 614.0
HKD2_k127_1433139_1 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 543.0
HKD2_k127_1433139_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 454.0
HKD2_k127_1433139_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000302 282.0
HKD2_k127_1433139_4 Peptidase family S49 K04773,K04774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000387 274.0
HKD2_k127_1433139_5 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000005225 248.0
HKD2_k127_1433139_6 Putative prokaryotic signal transducing protein - - - 0.00000731 51.0
HKD2_k127_1435296_0 Glucose / Sorbosone dehydrogenase K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 461.0
HKD2_k127_1435296_1 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 399.0
HKD2_k127_1435296_10 PQ loop repeat K15383 - - 0.0000000000000000000000001656 109.0
HKD2_k127_1435296_11 Tetratricopeptide repeat - - - 0.000000000008746 65.0
HKD2_k127_1435296_12 - - - - 0.00003872 54.0
HKD2_k127_1435296_13 Glycosyltransferase family 87 - - - 0.0001341 45.0
HKD2_k127_1435296_2 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 362.0
HKD2_k127_1435296_3 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 338.0
HKD2_k127_1435296_4 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000968 284.0
HKD2_k127_1435296_5 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000005239 254.0
HKD2_k127_1435296_6 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000003427 172.0
HKD2_k127_1435296_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000002205 166.0
HKD2_k127_1435296_8 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000000005864 155.0
HKD2_k127_1435296_9 repeat-containing protein - - - 0.00000000000000000000000000000006594 126.0
HKD2_k127_1437373_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 449.0
HKD2_k127_1437373_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 436.0
HKD2_k127_1437373_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004871 276.0
HKD2_k127_1456815_0 peptidase, M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 406.0
HKD2_k127_1456815_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001009 252.0
HKD2_k127_1469422_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 8.445e-285 885.0
HKD2_k127_1469422_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 604.0
HKD2_k127_1469422_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 287.0
HKD2_k127_1469422_11 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000001324 198.0
HKD2_k127_1469422_12 Belongs to the HesB IscA family K13628,K15724 - - 0.00000000000000000000000000000000000000000000004123 172.0
HKD2_k127_1469422_13 Response regulator receiver - - - 0.00000000000000000000000000000007692 139.0
HKD2_k127_1469422_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000000000000001554 120.0
HKD2_k127_1469422_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.000000000000000000000002731 104.0
HKD2_k127_1469422_2 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 516.0
HKD2_k127_1469422_3 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 441.0
HKD2_k127_1469422_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 395.0
HKD2_k127_1469422_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 387.0
HKD2_k127_1469422_6 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 361.0
HKD2_k127_1469422_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 352.0
HKD2_k127_1469422_8 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 355.0
HKD2_k127_1469422_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 331.0
HKD2_k127_1473472_0 Thiamine pyrophosphate enzyme, central domain - - - 3.788e-241 758.0
HKD2_k127_1473472_1 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 385.0
HKD2_k127_1473472_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004834 280.0
HKD2_k127_1473472_3 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000000000000000000000000000005977 156.0
HKD2_k127_1483223_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 382.0
HKD2_k127_1483223_1 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000001617 188.0
HKD2_k127_1483223_2 pathogenesis - - - 0.00000000000000000000000008751 115.0
HKD2_k127_1483223_3 Protein of unknown function (DUF1015) - - - 0.000000000002437 67.0
HKD2_k127_1493012_0 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 2540.0
HKD2_k127_1493012_1 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 419.0
HKD2_k127_1493012_2 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000000000000009863 223.0
HKD2_k127_1493012_3 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0003438 51.0
HKD2_k127_1505704_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 447.0
HKD2_k127_1505704_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007236 233.0
HKD2_k127_1505704_2 Pyridoxal-phosphate dependent enzyme K01754 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.00000000000000000000000000000000000000003507 154.0
HKD2_k127_1549084_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1095.0
HKD2_k127_1549084_1 MMPL family K07003 - - 0.0 1066.0
HKD2_k127_1549084_10 Flavodoxin-like fold K19784 - - 0.00000000000000000000000000000000000000000000000000000000003632 211.0
HKD2_k127_1549084_11 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000001343 188.0
HKD2_k127_1549084_12 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000006331 194.0
HKD2_k127_1549084_13 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000000000000000000000009484 186.0
HKD2_k127_1549084_14 Protein of unknown function (DUF1491) - - - 0.0000000000000000000000000000000000000000000003939 169.0
HKD2_k127_1549084_15 - - - - 0.000000000000000000000000000000000004441 142.0
HKD2_k127_1549084_16 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000001318 145.0
HKD2_k127_1549084_17 Transposase K07492 - - 0.0000000000000000000000000003658 113.0
HKD2_k127_1549084_18 Family of unknown function (DUF5330) - - - 0.00000000000000000000001055 105.0
HKD2_k127_1549084_19 - - - - 0.0000000000000000000004162 96.0
HKD2_k127_1549084_2 Histidine kinase K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 3.597e-220 699.0
HKD2_k127_1549084_20 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000009871 106.0
HKD2_k127_1549084_21 COG1002 Type II restriction enzyme, methylase subunits - - - 0.00000000000000000001939 97.0
HKD2_k127_1549084_22 COG1002 Type II restriction enzyme, methylase subunits - - - 0.000000000000135 73.0
HKD2_k127_1549084_23 - - - - 0.0000000000005755 71.0
HKD2_k127_1549084_24 Acetyltransferase (GNAT) domain - - - 0.00000001061 59.0
HKD2_k127_1549084_25 - - - - 0.00000003771 58.0
HKD2_k127_1549084_26 Acetyltransferase (GNAT) domain - - - 0.0000003397 57.0
HKD2_k127_1549084_3 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 491.0
HKD2_k127_1549084_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 503.0
HKD2_k127_1549084_5 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 449.0
HKD2_k127_1549084_6 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007007 287.0
HKD2_k127_1549084_7 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 271.0
HKD2_k127_1549084_8 Putative zinc- or iron-chelating domain K09160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003719 255.0
HKD2_k127_1549084_9 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001553 257.0
HKD2_k127_1555980_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1118.0
HKD2_k127_1555980_1 phosphorylase activity K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 7.059e-259 805.0
HKD2_k127_1555980_2 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 396.0
HKD2_k127_1555980_3 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000001689 153.0
HKD2_k127_1555980_4 Diguanylate cyclase - - - 0.00000000000000000000000000002423 125.0
HKD2_k127_1555980_5 Beta-Casp domain K07576 - - 0.00000000000000000000005198 106.0
HKD2_k127_1587389_0 Thi4 family K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 2.085e-291 902.0
HKD2_k127_1587389_1 PFAM Xanthine uracil vitamin C permease K06901 - - 1.595e-201 637.0
HKD2_k127_1587389_2 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 357.0
HKD2_k127_1587389_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005972 258.0
HKD2_k127_1587389_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000149 123.0
HKD2_k127_1587389_5 Dienelactone hydrolase family - - - 0.000000000000000000000000000004627 129.0
HKD2_k127_1641090_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 302.0
HKD2_k127_1641090_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 295.0
HKD2_k127_1641090_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000012 256.0
HKD2_k127_1641090_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000002886 111.0
HKD2_k127_1696840_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1198.0
HKD2_k127_1696840_1 Heparinase II/III-like protein - - - 4.441e-220 698.0
HKD2_k127_1696840_10 synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000004061 178.0
HKD2_k127_1696840_11 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000000007235 152.0
HKD2_k127_1696840_12 Protein of unknown function (DUF1761) - - - 0.00000000000000000000000000000009827 129.0
HKD2_k127_1696840_13 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000007604 128.0
HKD2_k127_1696840_14 DDE superfamily endonuclease - - - 0.000000000000001689 75.0
HKD2_k127_1696840_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 592.0
HKD2_k127_1696840_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 516.0
HKD2_k127_1696840_4 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
HKD2_k127_1696840_5 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 466.0
HKD2_k127_1696840_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 385.0
HKD2_k127_1696840_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 332.0
HKD2_k127_1696840_8 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000005101 209.0
HKD2_k127_1696840_9 EVE domain - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
HKD2_k127_1711802_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 397.0
HKD2_k127_1711802_1 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 300.0
HKD2_k127_1711802_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000001604 188.0
HKD2_k127_180037_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 524.0
HKD2_k127_180037_1 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 481.0
HKD2_k127_180037_2 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 399.0
HKD2_k127_180037_3 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 360.0
HKD2_k127_180037_4 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 329.0
HKD2_k127_180037_5 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 308.0
HKD2_k127_180037_6 DegT/DnrJ/EryC1/StrS aminotransferase family K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 294.0
HKD2_k127_180037_7 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 261.0
HKD2_k127_180037_8 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
HKD2_k127_180508_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 557.0
HKD2_k127_180508_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 428.0
HKD2_k127_180508_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006141 255.0
HKD2_k127_1850130_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 2.082e-220 689.0
HKD2_k127_1850130_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 554.0
HKD2_k127_1850130_11 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00003086 53.0
HKD2_k127_1850130_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 537.0
HKD2_k127_1850130_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 544.0
HKD2_k127_1850130_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 335.0
HKD2_k127_1850130_5 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 312.0
HKD2_k127_1850130_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006074 249.0
HKD2_k127_1850130_7 - - - - 0.000000000000000000000000000007761 123.0
HKD2_k127_1850130_8 - - - - 0.00000000000000000000005593 100.0
HKD2_k127_1850130_9 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000001143 58.0
HKD2_k127_1854152_0 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.0 1017.0
HKD2_k127_1854152_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 4.174e-252 794.0
HKD2_k127_1854152_10 PFAM AIG2 family protein - - - 0.0000000000000000000000000000005555 129.0
HKD2_k127_1854152_11 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000024 120.0
HKD2_k127_1854152_2 alcohol dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 589.0
HKD2_k127_1854152_3 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 393.0
HKD2_k127_1854152_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 363.0
HKD2_k127_1854152_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 335.0
HKD2_k127_1854152_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000008472 215.0
HKD2_k127_1854152_7 Domain of unknown function (DUF4399) - - - 0.000000000000000000000000000000000000000000000000006587 184.0
HKD2_k127_1854152_8 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000002301 174.0
HKD2_k127_1854152_9 Thioredoxin-like - - - 0.00000000000000000000000000000000000000002808 158.0
HKD2_k127_1864780_0 Protein of unknown function (DUF3168) - - - 0.0000000000000000000000000000000000000000000000000000000000001335 214.0
HKD2_k127_1864780_1 Phage gp6-like head-tail connector protein - - - 0.00000000000000000000000000000000000000000000000000000001161 205.0
HKD2_k127_1864780_2 Phage head-tail joining protein - - - 0.000000000000000000001004 104.0
HKD2_k127_1890399_0 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 365.0
HKD2_k127_1890399_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 295.0
HKD2_k127_1890399_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008908 261.0
HKD2_k127_1923404_0 ATPases associated with a variety of cellular activities K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 331.0
HKD2_k127_1923404_1 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 291.0
HKD2_k127_1923404_2 Hydrogenase urease accessory protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000181 234.0
HKD2_k127_1923404_3 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000000007557 201.0
HKD2_k127_1923404_4 Belongs to the urease gamma subunit family K01430,K14048 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000004415 187.0
HKD2_k127_1934146_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 6.738e-244 765.0
HKD2_k127_1934146_1 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000004125 230.0
HKD2_k127_1934146_2 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000005943 158.0
HKD2_k127_1965839_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 560.0
HKD2_k127_1965839_1 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000008432 265.0
HKD2_k127_1965839_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000001279 164.0
HKD2_k127_1965839_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000001427 130.0
HKD2_k127_202425_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 335.0
HKD2_k127_202425_1 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 316.0
HKD2_k127_202425_2 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000007742 116.0
HKD2_k127_202425_3 Receptor family ligand binding region K01999 - - 0.0000000007458 59.0
HKD2_k127_2032824_0 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 515.0
HKD2_k127_2032824_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 304.0
HKD2_k127_2032824_2 Aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002577 257.0
HKD2_k127_2032824_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000001456 234.0
HKD2_k127_2032824_4 Protein of unknown function (DUF1289) K06938 - - 0.0000000003022 63.0
HKD2_k127_2038012_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.544e-288 893.0
HKD2_k127_2038012_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 429.0
HKD2_k127_2038012_2 Transcriptional - - - 0.000000000000007712 75.0
HKD2_k127_2055124_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.186e-261 809.0
HKD2_k127_2055124_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 1.238e-223 697.0
HKD2_k127_2055124_10 Chemotaxis phosphatase, CheZ K03414 - - 0.0000000000000000000000001447 112.0
HKD2_k127_2055124_11 Major Facilitator Superfamily - - - 0.0003573 49.0
HKD2_k127_2055124_2 glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 471.0
HKD2_k127_2055124_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 397.0
HKD2_k127_2055124_4 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
HKD2_k127_2055124_5 ErfK YbiS YcfS YnhG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
HKD2_k127_2055124_6 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008499 256.0
HKD2_k127_2055124_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000000003374 186.0
HKD2_k127_2055124_8 - - - - 0.000000000000000000000000000000000000000000000005328 180.0
HKD2_k127_207934_0 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 572.0
HKD2_k127_207934_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 545.0
HKD2_k127_207934_10 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000001181 223.0
HKD2_k127_207934_11 ApaG domain K06195 - - 0.00000000000000000000000000000001356 128.0
HKD2_k127_207934_2 OpgC protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 518.0
HKD2_k127_207934_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 492.0
HKD2_k127_207934_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 458.0
HKD2_k127_207934_5 Transcriptional regulatory protein, C terminal K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 405.0
HKD2_k127_207934_6 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 354.0
HKD2_k127_207934_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 314.0
HKD2_k127_207934_8 GcrA cell cycle regulator K13583 - - 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
HKD2_k127_207934_9 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000999 222.0
HKD2_k127_2128523_0 E1 component K00164 - 1.2.4.2 0.0 1659.0
HKD2_k127_2128523_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1088.0
HKD2_k127_2128523_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000002089 160.0
HKD2_k127_2128523_11 - - - - 0.000000000000000000000000000000000000002362 152.0
HKD2_k127_2128523_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 3.98e-222 719.0
HKD2_k127_2128523_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 583.0
HKD2_k127_2128523_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 522.0
HKD2_k127_2128523_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 499.0
HKD2_k127_2128523_6 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 441.0
HKD2_k127_2128523_7 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000008463 259.0
HKD2_k127_2128523_8 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000427 253.0
HKD2_k127_2128523_9 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002978 235.0
HKD2_k127_2400320_0 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 442.0
HKD2_k127_2400320_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000001366 192.0
HKD2_k127_2400320_2 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000003644 182.0
HKD2_k127_2400320_3 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000000000209 170.0
HKD2_k127_2400320_4 Phosphopantetheine attachment site - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000001627 162.0
HKD2_k127_2400320_5 - - - - 0.000000000000000007649 89.0
HKD2_k127_240727_0 Proton-conducting membrane transporter - - - 8.731e-317 985.0
HKD2_k127_240727_1 Proton-conducting membrane transporter K12141 - - 6.714e-251 792.0
HKD2_k127_240727_10 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000003483 124.0
HKD2_k127_240727_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000001683 95.0
HKD2_k127_240727_12 Major facilitator superfamily K03449 - - 0.000000000000000000017 103.0
HKD2_k127_240727_2 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 479.0
HKD2_k127_240727_3 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 411.0
HKD2_k127_240727_4 Major facilitator superfamily K03449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 352.0
HKD2_k127_240727_5 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 347.0
HKD2_k127_240727_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003597 257.0
HKD2_k127_240727_7 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007202 258.0
HKD2_k127_240727_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000001355 235.0
HKD2_k127_240727_9 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000007441 180.0
HKD2_k127_2407847_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 3.235e-247 775.0
HKD2_k127_2407847_1 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 552.0
HKD2_k127_2407847_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 420.0
HKD2_k127_2407847_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000001131 223.0
HKD2_k127_2407847_4 - - - - 0.0000000000000000000000000000000000000000000000000000000002145 205.0
HKD2_k127_2407847_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000001818 175.0
HKD2_k127_2407847_6 ATP-grasp domain K09181 - - 0.0000000000000000000000000000000000000000000001786 172.0
HKD2_k127_2407847_7 - - - - 0.00000000000000000000000000000000000000000001591 164.0
HKD2_k127_2407847_8 NIPSNAP - - - 0.00000000000000000000000009205 111.0
HKD2_k127_2407847_9 - - - - 0.00000000000000000000001605 111.0
HKD2_k127_243431_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.884e-248 777.0
HKD2_k127_243431_1 homoserine dehydrogenase K00003 - 1.1.1.3 6.09e-220 689.0
HKD2_k127_243431_10 - - - - 0.000000000000000000249 95.0
HKD2_k127_243431_11 Cache domain - - - 0.000000000000007466 78.0
HKD2_k127_243431_12 Putative diguanylate phosphodiesterase - - - 0.00000002049 61.0
HKD2_k127_243431_2 Belongs to the thiolase family K00626 - 2.3.1.9 1.31e-204 642.0
HKD2_k127_243431_3 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 473.0
HKD2_k127_243431_4 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 435.0
HKD2_k127_243431_5 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 398.0
HKD2_k127_243431_6 DedA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
HKD2_k127_243431_7 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004842 242.0
HKD2_k127_243431_8 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000008903 158.0
HKD2_k127_243431_9 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000004241 94.0
HKD2_k127_2438938_0 FAD binding domain K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 587.0
HKD2_k127_2438938_1 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 463.0
HKD2_k127_2438938_2 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000001052 184.0
HKD2_k127_2502719_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 334.0
HKD2_k127_2502719_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 317.0
HKD2_k127_2502719_2 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 303.0
HKD2_k127_2502719_3 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000007035 245.0
HKD2_k127_2502719_4 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000001247 91.0
HKD2_k127_2511621_0 Branched-chain amino acid transport system / permease component K01997,K01998 - - 6.731e-271 846.0
HKD2_k127_2511621_1 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 355.0
HKD2_k127_2511621_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 329.0
HKD2_k127_2511621_3 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 331.0
HKD2_k127_2511621_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000389 249.0
HKD2_k127_2511621_5 helix_turn_helix multiple antibiotic resistance protein K22296 - - 0.000000000000000000000000000000000000000000000003472 178.0
HKD2_k127_2511621_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000003158 114.0
HKD2_k127_2511621_7 Receptor family ligand binding region K01999 - - 0.0000000000000000000007966 95.0
HKD2_k127_2511621_8 protein homotetramerization - - - 0.00000000004932 69.0
HKD2_k127_253709_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 533.0
HKD2_k127_253709_1 FeoA K04758 - - 0.000000000000000000004511 94.0
HKD2_k127_253709_2 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000008506 77.0
HKD2_k127_253709_3 Acyl-CoA dehydrogenase N terminal K00249 - 1.3.8.7 0.000000000179 61.0
HKD2_k127_2557163_0 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 569.0
HKD2_k127_2557163_1 Tetratricopeptide repeat K03671,K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 433.0
HKD2_k127_2557163_2 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 360.0
HKD2_k127_2557163_3 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004682 280.0
HKD2_k127_2557163_4 YbaK prolyl-tRNA synthetase K19055 - - 0.00000000000000000000000000000000000000000000000000000000000000000002402 236.0
HKD2_k127_2557163_5 Thioesterase-like superfamily K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000001871 130.0
HKD2_k127_2557163_6 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000000000000296 117.0
HKD2_k127_2557163_7 - - - - 0.00000002157 56.0
HKD2_k127_259598_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 566.0
HKD2_k127_259598_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 450.0
HKD2_k127_259598_2 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 356.0
HKD2_k127_259598_3 Amidohydrolase family K01443 GO:0003674,GO:0003824,GO:0005488,GO:0006040,GO:0006044,GO:0006046,GO:0006054,GO:0006082,GO:0008150,GO:0008152,GO:0008270,GO:0008448,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0016999,GO:0017001,GO:0017144,GO:0019213,GO:0019262,GO:0019752,GO:0022607,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046348,GO:0046395,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 354.0
HKD2_k127_2618384_0 methionine biosynthesis protein (MetW) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 349.0
HKD2_k127_2618384_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 332.0
HKD2_k127_2618384_2 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 332.0
HKD2_k127_2618384_3 CHAP domain - - - 0.0000000000000000000000000000000000000000001946 168.0
HKD2_k127_2618384_4 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000006563 77.0
HKD2_k127_2620056_0 Beta-ketoacyl synthase, C-terminal domain K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 7.831e-210 655.0
HKD2_k127_2620056_1 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 325.0
HKD2_k127_2620056_2 Bacterial SH3 domain K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000006638 225.0
HKD2_k127_2620056_3 Ferric uptake regulator family K09826 - - 0.00000000000000000000000000000000000000000000000000000000000000007991 225.0
HKD2_k127_2620352_0 Diguanylate cyclase K13245 - 3.1.4.52 1.668e-291 900.0
HKD2_k127_2620352_1 Uncharacterized ACR, COG1678 K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 333.0
HKD2_k127_2620352_2 Disulphide bond corrector protein DsbC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001824 254.0
HKD2_k127_2620352_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001036 241.0
HKD2_k127_2620352_4 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000002069 227.0
HKD2_k127_2650169_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.185e-205 641.0
HKD2_k127_2650169_1 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 527.0
HKD2_k127_2650169_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 350.0
HKD2_k127_2650169_3 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000003108 235.0
HKD2_k127_2650169_4 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
HKD2_k127_2678260_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000006631 204.0
HKD2_k127_2678260_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000006192 188.0
HKD2_k127_2678260_2 YtkA-like - - - 0.0000000000000000000000000000000000000000000000007446 179.0
HKD2_k127_2679534_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1122.0
HKD2_k127_2679534_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 0.0 1054.0
HKD2_k127_2679534_10 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000004584 173.0
HKD2_k127_2679534_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000528 132.0
HKD2_k127_2679534_12 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000002388 112.0
HKD2_k127_2679534_13 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000000003762 72.0
HKD2_k127_2679534_14 Fumarylacetoacetate (FAA) hydrolase family K18336 - - 0.0005948 42.0
HKD2_k127_2679534_2 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 8.947e-285 893.0
HKD2_k127_2679534_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 3.72e-196 621.0
HKD2_k127_2679534_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 4.578e-195 621.0
HKD2_k127_2679534_5 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 587.0
HKD2_k127_2679534_6 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 514.0
HKD2_k127_2679534_7 Dimerisation domain of Zinc Transporter K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 463.0
HKD2_k127_2679534_8 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 363.0
HKD2_k127_2679534_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 313.0
HKD2_k127_2697119_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1159.0
HKD2_k127_2697119_1 Domain of unknown function (DUF3459) K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 439.0
HKD2_k127_2697119_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 285.0
HKD2_k127_2697119_3 Alpha-amylase domain K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006112 274.0
HKD2_k127_2697119_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003712 252.0
HKD2_k127_2697119_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002434 228.0
HKD2_k127_2697119_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000001535 179.0
HKD2_k127_2697119_7 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.000000007852 57.0
HKD2_k127_2702834_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 554.0
HKD2_k127_2702834_1 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 415.0
HKD2_k127_2702834_2 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001661 236.0
HKD2_k127_2704324_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 372.0
HKD2_k127_2704324_1 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001199 275.0
HKD2_k127_2704324_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000584 244.0
HKD2_k127_2704324_3 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008343 244.0
HKD2_k127_2718670_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005738 267.0
HKD2_k127_2718670_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004422 254.0
HKD2_k127_2718670_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000003233 65.0
HKD2_k127_2739404_0 Dehydratase family K01687 - 4.2.1.9 3.917e-263 817.0
HKD2_k127_2739404_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.776e-226 706.0
HKD2_k127_2739404_2 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000004655 226.0
HKD2_k127_2739404_3 Protein of unknown function (DUF2948) - - - 0.00000000000000000000000000000000000000000000000000006236 191.0
HKD2_k127_2739404_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001668 165.0
HKD2_k127_2739404_5 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000167 161.0
HKD2_k127_2739404_6 Glycosyl transferase, family 2 K01002 - 2.7.8.20 0.00000000000000000000000000000009925 134.0
HKD2_k127_2739404_7 Glycosyl transferase, family 2 K01002 - 2.7.8.20 0.0000000007034 70.0
HKD2_k127_2739404_8 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0005125 48.0
HKD2_k127_2741638_0 TIGRFAM cytochrome c oxidase, cbb3-type, subunit I K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.0 998.0
HKD2_k127_2741638_1 GHKL domain K14986 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 406.0
HKD2_k127_2741638_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 395.0
HKD2_k127_2741638_3 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002589 269.0
HKD2_k127_2741638_4 Crp Fnr family K01420,K15861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009396 261.0
HKD2_k127_2741638_5 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000001071 197.0
HKD2_k127_2741638_6 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000009024 142.0
HKD2_k127_2760198_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1070.0
HKD2_k127_2760198_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.625e-212 665.0
HKD2_k127_2760198_2 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 444.0
HKD2_k127_2760198_3 COG0530 Ca2 Na antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004025 289.0
HKD2_k127_2760198_4 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001067 240.0
HKD2_k127_2760198_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000001448 201.0
HKD2_k127_2760198_6 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000000000000009144 173.0
HKD2_k127_2760198_7 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000004639 81.0
HKD2_k127_2760198_8 N-methylhydantoinase A acetone carboxylase, beta subunit K01469 - 3.5.2.9 0.00000000000003526 79.0
HKD2_k127_2760198_9 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0003457 48.0
HKD2_k127_2761682_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 361.0
HKD2_k127_2761682_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000003949 139.0
HKD2_k127_2761682_2 - - - - 0.00000000000000000000000000638 118.0
HKD2_k127_276298_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 9.699e-260 817.0
HKD2_k127_276298_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 505.0
HKD2_k127_276298_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 310.0
HKD2_k127_276298_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005369 256.0
HKD2_k127_276298_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000106 172.0
HKD2_k127_276298_5 Cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000006372 78.0
HKD2_k127_2768863_0 Natural resistance-associated macrophage protein K03322 - - 3.02e-196 621.0
HKD2_k127_2768863_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 562.0
HKD2_k127_2768863_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 422.0
HKD2_k127_2768863_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 339.0
HKD2_k127_2768863_4 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000003373 224.0
HKD2_k127_2768863_5 Helix-turn-helix diphteria tox regulatory element K11924 - - 0.000000000000000000000000000000000000000000000000000000000008475 211.0
HKD2_k127_2768863_6 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000001098 81.0
HKD2_k127_2769639_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 586.0
HKD2_k127_2776905_0 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 294.0
HKD2_k127_2776905_1 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000005125 144.0
HKD2_k127_2776905_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000001594 116.0
HKD2_k127_2776905_3 Carbon monoxide dehydrogenase subunit G (CoxG) K16877 - 1.3.99.8 0.0004406 49.0
HKD2_k127_2786146_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 331.0
HKD2_k127_2786146_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000002176 168.0
HKD2_k127_2786146_2 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000002668 142.0
HKD2_k127_2786146_3 NADPH-dependent FMN reductase - - - 0.00002705 47.0
HKD2_k127_2798694_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 5.946e-306 944.0
HKD2_k127_2798694_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 6.352e-249 777.0
HKD2_k127_2798694_10 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 306.0
HKD2_k127_2798694_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000008026 235.0
HKD2_k127_2798694_12 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000001636 127.0
HKD2_k127_2798694_13 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000001359 127.0
HKD2_k127_2798694_14 Competence protein K02238 - - 0.0000000000000000000000000005793 117.0
HKD2_k127_2798694_15 Competence protein K02238 - - 0.000000000000002515 83.0
HKD2_k127_2798694_16 Competence protein K02238 - - 0.0000000000002875 71.0
HKD2_k127_2798694_17 Competence protein K02238 - - 0.00000007665 58.0
HKD2_k127_2798694_18 Competence protein K02238 - - 0.00003188 47.0
HKD2_k127_2798694_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.102e-199 621.0
HKD2_k127_2798694_3 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 8.976e-197 634.0
HKD2_k127_2798694_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 518.0
HKD2_k127_2798694_5 MoeA C-terminal region (domain IV) K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 486.0
HKD2_k127_2798694_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 399.0
HKD2_k127_2798694_7 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 381.0
HKD2_k127_2798694_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 334.0
HKD2_k127_2798694_9 Domain of unknown function (DUF4131) K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 328.0
HKD2_k127_2811122_0 Pyridoxal-phosphate dependent enzyme K01754 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 343.0
HKD2_k127_2811122_1 Major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005713 282.0
HKD2_k127_2811122_2 - - - - 0.000000000000000000000000002522 115.0
HKD2_k127_2811122_3 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) - - - 0.0000004924 60.0
HKD2_k127_2817353_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 2.344e-262 816.0
HKD2_k127_2817353_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.102e-195 615.0
HKD2_k127_2828640_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 561.0
HKD2_k127_2828640_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 469.0
HKD2_k127_2828640_10 Domain of unknown function (DUF3597) - - - 0.00000000000000000001221 94.0
HKD2_k127_2828640_11 Domain of unknown function (DUF3597) - - - 0.000000000000000002946 84.0
HKD2_k127_2828640_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 415.0
HKD2_k127_2828640_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 387.0
HKD2_k127_2828640_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 373.0
HKD2_k127_2828640_5 PAS fold - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
HKD2_k127_2828640_6 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000001816 211.0
HKD2_k127_2828640_7 Transglycosylase associated protein - - - 0.0000000000000000000000000000000000000004456 152.0
HKD2_k127_2828640_8 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000004057 125.0
HKD2_k127_2828640_9 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000007792 107.0
HKD2_k127_2834222_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.512e-314 974.0
HKD2_k127_2834222_1 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 4.178e-305 946.0
HKD2_k127_2834222_2 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 3.542e-200 628.0
HKD2_k127_2834222_3 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 488.0
HKD2_k127_2834222_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 454.0
HKD2_k127_2834222_5 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 398.0
HKD2_k127_2834222_6 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 327.0
HKD2_k127_2834222_7 phytoene synthase K21678 - 2.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 327.0
HKD2_k127_2834222_8 MMPL family K07003 - - 0.00000000000000000000000000000000000000001355 158.0
HKD2_k127_2834222_9 LTXXQ motif family protein - - - 0.00000000000000000000000005984 122.0
HKD2_k127_2848759_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1150.0
HKD2_k127_2848759_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 594.0
HKD2_k127_2848759_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 490.0
HKD2_k127_2848759_3 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000000000000000000000000000006734 213.0
HKD2_k127_2848759_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000001706 191.0
HKD2_k127_2848759_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001068 151.0
HKD2_k127_2852731_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 1.723e-267 828.0
HKD2_k127_2852731_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 537.0
HKD2_k127_2852731_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 530.0
HKD2_k127_2852731_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 473.0
HKD2_k127_2852731_4 Polyketide cyclase / dehydrase and lipid transport K18588 - - 0.00000000000000000000000000000000000000000000000000000000000000000002467 234.0
HKD2_k127_2852731_5 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000005935 221.0
HKD2_k127_2852731_6 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000002481 202.0
HKD2_k127_2852731_7 PFAM Transglycosylase-associated protein - - - 0.00000000000002471 77.0
HKD2_k127_2870842_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 550.0
HKD2_k127_2870842_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 434.0
HKD2_k127_2870842_10 - - - - 0.0000000000000000002311 92.0
HKD2_k127_2870842_11 ABC transporter K06861 - - 0.000000000004321 70.0
HKD2_k127_2870842_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 409.0
HKD2_k127_2870842_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 362.0
HKD2_k127_2870842_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 360.0
HKD2_k127_2870842_5 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 325.0
HKD2_k127_2870842_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 262.0
HKD2_k127_2870842_7 OstA-like protein K09774 - - 0.000000000000000000000000000000000000000000000000000000000001684 218.0
HKD2_k127_2870842_8 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000000000000000009147 212.0
HKD2_k127_2870842_9 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001699 124.0
HKD2_k127_289400_0 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 574.0
HKD2_k127_2899240_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
HKD2_k127_2899240_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 417.0
HKD2_k127_2899240_2 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 379.0
HKD2_k127_2899240_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000003237 132.0
HKD2_k127_2951887_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1830.0
HKD2_k127_2951887_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 425.0
HKD2_k127_2951887_10 Transposase - - - 0.00000000000001957 73.0
HKD2_k127_2951887_2 Extensin-like protein C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 360.0
HKD2_k127_2951887_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 334.0
HKD2_k127_2951887_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
HKD2_k127_2951887_5 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 296.0
HKD2_k127_2951887_6 PFAM porin K16079 - - 0.00000000000000000000000000000000000000000000002987 178.0
HKD2_k127_2951887_7 - - - - 0.0000000000000000000000000000000000000000000007339 171.0
HKD2_k127_2951887_8 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000000424 138.0
HKD2_k127_2951887_9 - - - - 0.000000000000000000007827 99.0
HKD2_k127_2977207_0 MULE transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 402.0
HKD2_k127_2977207_1 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 316.0
HKD2_k127_2977207_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000149 233.0
HKD2_k127_2977207_3 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000002653 213.0
HKD2_k127_2977207_4 Winged helix-turn helix - - - 0.000000000000000001024 85.0
HKD2_k127_2977207_5 - - - - 0.0000000008368 65.0
HKD2_k127_2977207_6 - - - - 0.0003791 49.0
HKD2_k127_3008378_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 561.0
HKD2_k127_3008378_1 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 427.0
HKD2_k127_3008378_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 378.0
HKD2_k127_3008378_3 phosphatidylethanolamine N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 321.0
HKD2_k127_3008378_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 333.0
HKD2_k127_3008378_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 304.0
HKD2_k127_3008378_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000008872 234.0
HKD2_k127_3008378_7 Flavodoxin-like fold K19784 - - 0.0000000000000000000000000000000000000000000000000000000000832 209.0
HKD2_k127_3103525_0 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.0 1115.0
HKD2_k127_3103525_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000002717 230.0
HKD2_k127_3103525_2 methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000004886 214.0
HKD2_k127_3103525_3 Flagellar biosynthesis protein, FliO - - - 0.00000000000000000000000000000000000000000000000000005654 199.0
HKD2_k127_3103525_4 Cold shock K03704 - - 0.0000000000000000000000000007605 113.0
HKD2_k127_3112529_0 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 564.0
HKD2_k127_3112529_1 phosphate acetyltransferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 440.0
HKD2_k127_3235447_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 1.503e-234 736.0
HKD2_k127_3235447_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 515.0
HKD2_k127_3235447_2 MAPEG family - - - 0.00000000000000006654 81.0
HKD2_k127_3235447_3 Alpha beta hydrolase - - - 0.000000004314 67.0
HKD2_k127_3240998_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 380.0
HKD2_k127_3240998_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 296.0
HKD2_k127_3240998_2 - - - - 0.000000000000000000000000000000000397 141.0
HKD2_k127_3240998_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000008823 96.0
HKD2_k127_3248135_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 8.267e-303 934.0
HKD2_k127_3248135_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 6.746e-212 662.0
HKD2_k127_3248135_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 7.404e-197 618.0
HKD2_k127_3248135_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 522.0
HKD2_k127_3248135_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 471.0
HKD2_k127_3248135_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 305.0
HKD2_k127_3248135_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 296.0
HKD2_k127_3248135_7 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001468 276.0
HKD2_k127_3248135_8 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004603 263.0
HKD2_k127_3266702_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - - 6.722e-300 926.0
HKD2_k127_3266702_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 443.0
HKD2_k127_3266702_10 membrane K08988 - - 0.000000000000000000000000000000000000000000000000000000008299 207.0
HKD2_k127_3266702_11 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000002146 203.0
HKD2_k127_3266702_12 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000005096 202.0
HKD2_k127_3266702_13 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000007094 198.0
HKD2_k127_3266702_14 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000000000008017 176.0
HKD2_k127_3266702_15 Belongs to the UPF0306 family K09979 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000001629 170.0
HKD2_k127_3266702_16 Macrocin-O-methyltransferase (TylF) K05303,K15996,K19569 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0030769,GO:0032259,GO:0044237,GO:0044249 2.1.1.101,2.1.1.307 0.00000000000000000000000000000000000007733 147.0
HKD2_k127_3266702_17 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000001262 110.0
HKD2_k127_3266702_18 DNA repair - - - 0.0000000000000000000006174 106.0
HKD2_k127_3266702_2 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 400.0
HKD2_k127_3266702_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 335.0
HKD2_k127_3266702_4 Glycosyl transferase family group 2 K03669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 336.0
HKD2_k127_3266702_5 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 316.0
HKD2_k127_3266702_6 COG1985 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 308.0
HKD2_k127_3266702_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 287.0
HKD2_k127_3266702_8 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 271.0
HKD2_k127_3266702_9 Class II aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002678 232.0
HKD2_k127_3276440_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 485.0
HKD2_k127_3276440_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000003708 196.0
HKD2_k127_3276440_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000007168 48.0
HKD2_k127_328443_0 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 285.0
HKD2_k127_328443_1 membrane - - - 0.00000000005031 74.0
HKD2_k127_3304960_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 410.0
HKD2_k127_3304960_1 Chorismate mutase type II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 374.0
HKD2_k127_3304960_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 358.0
HKD2_k127_3312734_0 Penicillin-binding Protein K03587 - 3.4.16.4 7.096e-269 844.0
HKD2_k127_3312734_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 8.95e-196 621.0
HKD2_k127_3312734_10 secreted (periplasmic) protein - - - 0.000000000000000000000000001558 121.0
HKD2_k127_3312734_11 GIY-YIG type nucleases (URI domain) K07461 - - 0.0000000000000000000002258 96.0
HKD2_k127_3312734_12 Excinuclease ABC, C subunit K07461 - - 0.00000000001742 70.0
HKD2_k127_3312734_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 597.0
HKD2_k127_3312734_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 589.0
HKD2_k127_3312734_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 593.0
HKD2_k127_3312734_5 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 426.0
HKD2_k127_3312734_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 406.0
HKD2_k127_3312734_7 N-acetylmuramoyl-L-alanine amidase (Family 2) K01447,K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 359.0
HKD2_k127_3312734_8 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 347.0
HKD2_k127_3312734_9 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000000000000007567 220.0
HKD2_k127_3318217_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 309.0
HKD2_k127_3318217_1 Alcohol dehydrogenase zinc-binding domain protein K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000007953 197.0
HKD2_k127_3318217_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000009188 194.0
HKD2_k127_3318217_3 Amidohydrolase family K01485 - 3.5.4.1 0.000000000000000000000000000000000000006027 149.0
HKD2_k127_3318217_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000005792 80.0
HKD2_k127_3318217_5 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0002688 47.0
HKD2_k127_3320876_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1136.0
HKD2_k127_3320876_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 425.0
HKD2_k127_3320876_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 386.0
HKD2_k127_3320876_3 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 344.0
HKD2_k127_3320876_4 carbon monoxide dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 284.0
HKD2_k127_3320876_5 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000291 244.0
HKD2_k127_3320876_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
HKD2_k127_3320876_7 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.0000000000000000000000000000000000000000000000003268 180.0
HKD2_k127_3320876_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000004489 149.0
HKD2_k127_3323417_0 PHB de-polymerase C-terminus K05973 - 3.1.1.75 2.3e-214 677.0
HKD2_k127_3323417_1 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 556.0
HKD2_k127_3323417_10 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000000000000000000000000000000002648 212.0
HKD2_k127_3323417_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 531.0
HKD2_k127_3323417_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 404.0
HKD2_k127_3323417_4 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 391.0
HKD2_k127_3323417_5 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 385.0
HKD2_k127_3323417_6 Major Facilitator Superfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 390.0
HKD2_k127_3323417_7 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 375.0
HKD2_k127_3323417_8 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 372.0
HKD2_k127_3323417_9 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 286.0
HKD2_k127_336526_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1112.0
HKD2_k127_342328_0 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 518.0
HKD2_k127_342328_1 Transaldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 374.0
HKD2_k127_342328_2 heptosyltransferase K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008024 278.0
HKD2_k127_342328_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000001067 261.0
HKD2_k127_342328_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000483 257.0
HKD2_k127_342328_5 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000156 244.0
HKD2_k127_342328_6 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K05785 - - 0.0000000000000000000000000000000000000000000000000000001038 207.0
HKD2_k127_342328_7 transferase activity, transferring glycosyl groups - - - 0.000000000001153 80.0
HKD2_k127_3433607_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 4.334e-223 706.0
HKD2_k127_3452406_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 418.0
HKD2_k127_3452406_1 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 357.0
HKD2_k127_3473798_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 1.381e-278 866.0
HKD2_k127_3473798_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 6.662e-238 745.0
HKD2_k127_3473798_10 Binding-protein-dependent transport system inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 350.0
HKD2_k127_3473798_11 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 356.0
HKD2_k127_3473798_12 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 348.0
HKD2_k127_3473798_13 Belongs to the carbohydrate kinase PfkB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002542 263.0
HKD2_k127_3473798_14 transcriptional regulator, AsnC family K05800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004688 256.0
HKD2_k127_3473798_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000001938 249.0
HKD2_k127_3473798_16 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003767 228.0
HKD2_k127_3473798_17 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000007491 219.0
HKD2_k127_3473798_18 HIT domain - - - 0.00000000000000000000000000000000000000000000000003823 182.0
HKD2_k127_3473798_19 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000001404 154.0
HKD2_k127_3473798_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.851e-234 741.0
HKD2_k127_3473798_20 Tetratricopeptide repeat - - - 0.000000000000000000002094 104.0
HKD2_k127_3473798_21 4,5-dihydroxyphthalate decarboxylase - - - 0.00000000000000000001472 93.0
HKD2_k127_3473798_22 TadE-like protein - - - 0.00000001045 59.0
HKD2_k127_3473798_23 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0000001244 57.0
HKD2_k127_3473798_3 Acetyl-coenzyme A transporter 1 K08218 - - 1.557e-198 628.0
HKD2_k127_3473798_4 Acyl-CoA dehydrogenase, C-terminal domain K19966 - 3.13.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 605.0
HKD2_k127_3473798_5 N-terminal TM domain of oligopeptide transport permease C K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 592.0
HKD2_k127_3473798_6 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 585.0
HKD2_k127_3473798_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 453.0
HKD2_k127_3473798_8 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 371.0
HKD2_k127_3473798_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 357.0
HKD2_k127_358083_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 8.092e-225 710.0
HKD2_k127_358083_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 445.0
HKD2_k127_358083_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 386.0
HKD2_k127_358083_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 353.0
HKD2_k127_358083_4 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 312.0
HKD2_k127_358083_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000001891 227.0
HKD2_k127_358083_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.000000000000000000000000000000000004589 139.0
HKD2_k127_3610170_0 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 482.0
HKD2_k127_3610170_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 391.0
HKD2_k127_3610170_2 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 326.0
HKD2_k127_3610170_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004076 255.0
HKD2_k127_3610170_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000002248 115.0
HKD2_k127_3610170_5 Putative mono-oxygenase ydhR - - - 0.000000000000000000000008344 106.0
HKD2_k127_366652_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002355 236.0
HKD2_k127_366652_2 - - - - 0.00000000000000000000000000000000000000001798 162.0
HKD2_k127_366652_3 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0008741 42.0
HKD2_k127_37279_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 5.672e-222 715.0
HKD2_k127_37279_1 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 393.0
HKD2_k127_37279_2 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 362.0
HKD2_k127_37279_3 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000003519 231.0
HKD2_k127_37279_4 Hydrogenase expression formation protein (HypE) K04655,K07492,K08303 - - 0.000000000000007841 73.0
HKD2_k127_3782778_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 435.0
HKD2_k127_3782778_1 Protein of unknown function (DUF1153) - - - 0.000000000000000000000000000000000000000000000000005581 181.0
HKD2_k127_3782778_2 Sigma-54 interaction domain K10943 - - 0.0000000000000000000000008695 107.0
HKD2_k127_38449_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1210.0
HKD2_k127_38449_1 tRNA synthetases class II core domain (F) K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 1.916e-197 622.0
HKD2_k127_38449_10 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000002156 126.0
HKD2_k127_38449_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 439.0
HKD2_k127_38449_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 379.0
HKD2_k127_38449_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 371.0
HKD2_k127_38449_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 350.0
HKD2_k127_38449_6 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 328.0
HKD2_k127_38449_7 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001229 286.0
HKD2_k127_38449_8 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000000000000000000000000000001066 220.0
HKD2_k127_38449_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000001597 207.0
HKD2_k127_3926163_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1417.0
HKD2_k127_3926163_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 322.0
HKD2_k127_3926163_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000036 276.0
HKD2_k127_3926163_3 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003985 260.0
HKD2_k127_3926163_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009499 251.0
HKD2_k127_3926163_5 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000000006946 223.0
HKD2_k127_3926163_6 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000005428 173.0
HKD2_k127_3926163_7 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000000000000000000004059 165.0
HKD2_k127_3926187_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 322.0
HKD2_k127_3926187_1 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 263.0
HKD2_k127_3926187_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000008933 239.0
HKD2_k127_3926187_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0000000000000000003987 88.0
HKD2_k127_3927366_0 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 334.0
HKD2_k127_3927366_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007325 246.0
HKD2_k127_3927366_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000004067 141.0
HKD2_k127_3927366_3 Cysteine-rich secretory protein family - - - 0.0000543 48.0
HKD2_k127_3954298_0 Thiolase, C-terminal domain - - - 5.283e-199 625.0
HKD2_k127_3954298_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 503.0
HKD2_k127_3954298_2 GntR family - - - 0.00000000000000000000000000000000000000000000000000000000000001384 220.0
HKD2_k127_3954849_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1454.0
HKD2_k127_3954849_1 Peptidase family M23 - - - 3.959e-270 848.0
HKD2_k127_3954849_2 - - - - 0.0000000000001022 73.0
HKD2_k127_3960702_0 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 1.413e-213 667.0
HKD2_k127_3960702_1 Acts as a magnesium transporter K06213 - - 7.861e-196 621.0
HKD2_k127_3960702_10 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000009145 90.0
HKD2_k127_3960702_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 556.0
HKD2_k127_3960702_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 451.0
HKD2_k127_3960702_4 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 309.0
HKD2_k127_3960702_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 303.0
HKD2_k127_3960702_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 297.0
HKD2_k127_3960702_7 Cupredoxin-like domain - - - 0.000000000000000000000000000006098 122.0
HKD2_k127_3960702_8 Aldo/keto reductase family - - - 0.0000000000000000000000008199 108.0
HKD2_k127_3960702_9 transcriptional regulator, XRE family K07726 - - 0.000000000000000000000001728 106.0
HKD2_k127_3965427_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 466.0
HKD2_k127_3965427_1 SNARE associated golgi protein - - - 0.000000000000000000000000000000000000000000000000000004698 204.0
HKD2_k127_3965427_2 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000002562 60.0
HKD2_k127_3975760_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 423.0
HKD2_k127_3975760_1 PFAM Phasin 2 family protein - - - 0.00000000000000000000000001611 114.0
HKD2_k127_3975760_2 TIGRFAM phasin - - - 0.0001373 49.0
HKD2_k127_3982524_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 524.0
HKD2_k127_3982524_1 TIGRFAM lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000001762 209.0
HKD2_k127_3982524_2 Protein of unknown function (DUF2865) - - - 0.0000000000000000000000000000000000000000006234 167.0
HKD2_k127_3982524_3 Citrate transporter - - - 0.00000000000000000000000000000000002392 135.0
HKD2_k127_39876_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K15783 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 433.0
HKD2_k127_39876_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 402.0
HKD2_k127_39876_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 380.0
HKD2_k127_3991416_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.199e-308 977.0
HKD2_k127_3991416_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 548.0
HKD2_k127_3991416_10 cytochrome - - - 0.0000003469 58.0
HKD2_k127_3991416_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 499.0
HKD2_k127_3991416_3 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 383.0
HKD2_k127_3991416_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 351.0
HKD2_k127_3991416_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 353.0
HKD2_k127_3991416_6 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 336.0
HKD2_k127_3991416_7 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000008767 265.0
HKD2_k127_3991416_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
HKD2_k127_3991416_9 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000004694 150.0
HKD2_k127_4007184_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.002e-218 691.0
HKD2_k127_4007184_1 ATPases associated with a variety of cellular activities K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002535 269.0
HKD2_k127_4007184_2 PTS IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 246.0
HKD2_k127_4007184_3 Protein of unknown function (DUF1150) - - - 0.00000000000000000000000000000000001265 137.0
HKD2_k127_4007184_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000006646 133.0
HKD2_k127_4007184_5 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000006773 74.0
HKD2_k127_4011353_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 8.256e-262 829.0
HKD2_k127_4011353_1 PFAM Rieske 2Fe-2S domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 585.0
HKD2_k127_4011353_10 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000008325 171.0
HKD2_k127_4011353_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 539.0
HKD2_k127_4011353_3 Phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 533.0
HKD2_k127_4011353_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 378.0
HKD2_k127_4011353_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 361.0
HKD2_k127_4011353_6 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 339.0
HKD2_k127_4011353_7 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005987 290.0
HKD2_k127_4011353_8 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008251 259.0
HKD2_k127_4011353_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000002771 176.0
HKD2_k127_4023612_0 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001498 286.0
HKD2_k127_4023612_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000003184 197.0
HKD2_k127_4023612_2 transposable element conserved - - - 0.000000000000000000000000000000002917 128.0
HKD2_k127_4023612_3 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000007929 131.0
HKD2_k127_4023612_4 von Willebrand factor type A domain - - - 0.000000000000000000000000004653 113.0
HKD2_k127_4023612_5 Protein of unknown function (DUF3592) - - - 0.00000000000000000000000007254 121.0
HKD2_k127_4023613_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000841 177.0
HKD2_k127_4023613_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000001143 139.0
HKD2_k127_4023613_2 transposable element conserved - - - 0.000000000000000000000000000000002917 128.0
HKD2_k127_4026169_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.327e-238 741.0
HKD2_k127_4026169_1 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 383.0
HKD2_k127_4026169_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 325.0
HKD2_k127_4026169_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000001763 253.0
HKD2_k127_4026169_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000003372 234.0
HKD2_k127_4026169_5 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000001013 205.0
HKD2_k127_4026169_6 Smr domain - - - 0.0000000000000000000000000000000000000000000000000006925 189.0
HKD2_k127_4026169_7 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000002393 64.0
HKD2_k127_4026169_8 Staphylococcal nuclease homologue - - - 0.000000209 61.0
HKD2_k127_4056603_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.356e-217 691.0
HKD2_k127_4056603_1 PFAM NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 405.0
HKD2_k127_4056603_2 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006336 281.0
HKD2_k127_4056603_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005343 281.0
HKD2_k127_4056603_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000006801 191.0
HKD2_k127_4056603_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000008356 127.0
HKD2_k127_4061436_0 Tripartite tricarboxylate transporter TctA family K07793 - - 5.187e-251 785.0
HKD2_k127_4061436_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000106 268.0
HKD2_k127_4061436_2 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000001431 209.0
HKD2_k127_4061436_3 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000002314 194.0
HKD2_k127_4061436_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000001301 168.0
HKD2_k127_4061436_5 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000000000000000000001497 159.0
HKD2_k127_4061436_6 - - - - 0.0000000000000000000000000000000000000002667 156.0
HKD2_k127_4102300_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.47e-256 805.0
HKD2_k127_4102300_1 Alcohol dehydrogenase GroES-like domain K00055 - 1.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 368.0
HKD2_k127_4102300_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 288.0
HKD2_k127_4102300_3 AMP-binding enzyme - - - 0.000000000000001261 79.0
HKD2_k127_4102300_4 AMP-binding enzyme - - - 0.00000000001793 67.0
HKD2_k127_4102300_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0001134 46.0
HKD2_k127_4127400_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 7.578e-220 692.0
HKD2_k127_4147069_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.004e-237 745.0
HKD2_k127_4147069_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 397.0
HKD2_k127_4147069_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 377.0
HKD2_k127_4147069_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 368.0
HKD2_k127_4147069_4 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008035 271.0
HKD2_k127_4147069_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
HKD2_k127_4147069_6 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000003832 254.0
HKD2_k127_4182526_0 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001164 241.0
HKD2_k127_4182526_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 242.0
HKD2_k127_4182526_2 FAD binding domain K03185 - - 0.00000000000000000000002062 101.0
HKD2_k127_4223287_0 sensor histidine kinase with a Response regulator receiver domain K02482 - 2.7.13.3 4.053e-294 918.0
HKD2_k127_4223287_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.531e-244 768.0
HKD2_k127_4223287_10 Response regulator receiver - - - 0.00000000000000000000000000000000003476 140.0
HKD2_k127_4223287_11 DsrE/DsrF-like family - - - 0.000000000000000000000000005133 116.0
HKD2_k127_4223287_12 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000001176 101.0
HKD2_k127_4223287_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.312e-226 710.0
HKD2_k127_4223287_3 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 606.0
HKD2_k127_4223287_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 568.0
HKD2_k127_4223287_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 536.0
HKD2_k127_4223287_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 524.0
HKD2_k127_4223287_7 Peptidase C26 K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 364.0
HKD2_k127_4223287_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 300.0
HKD2_k127_4223287_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000132 278.0
HKD2_k127_4239230_0 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 452.0
HKD2_k127_4239230_1 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 381.0
HKD2_k127_4239230_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 312.0
HKD2_k127_4239230_3 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000006018 247.0
HKD2_k127_4239230_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000009534 193.0
HKD2_k127_4239230_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000006092 151.0
HKD2_k127_4256637_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 488.0
HKD2_k127_4256637_1 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000001505 123.0
HKD2_k127_4256637_2 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000004539 78.0
HKD2_k127_4269294_0 C-C_Bond_Lyase of the TIM-Barrel fold K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 372.0
HKD2_k127_4269294_1 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
HKD2_k127_4269294_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000001522 160.0
HKD2_k127_4269294_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000001848 63.0
HKD2_k127_428095_0 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 364.0
HKD2_k127_428095_1 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 282.0
HKD2_k127_428095_10 - - - - 0.00000000000000000000000000000002788 135.0
HKD2_k127_428095_11 Domain of Unknown Function (DUF930) - - - 0.000000000000000000000000000001222 125.0
HKD2_k127_428095_12 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.000000000000000000000000000007752 120.0
HKD2_k127_428095_13 - - - - 0.0000000000000000000000001525 110.0
HKD2_k127_428095_14 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000002375 103.0
HKD2_k127_428095_15 Cysteine rich repeat - - - 0.000000000000005914 78.0
HKD2_k127_428095_16 Lipocalin-like domain - - - 0.000000000002469 73.0
HKD2_k127_428095_17 - - - - 0.0000000002944 65.0
HKD2_k127_428095_2 Glycosyltransferase family 87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001314 239.0
HKD2_k127_428095_3 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003736 240.0
HKD2_k127_428095_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000457 227.0
HKD2_k127_428095_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000006399 198.0
HKD2_k127_428095_6 Protein of unknown function (DUF3829) - - - 0.0000000000000000000000000000000000000000000001824 170.0
HKD2_k127_428095_7 - - - - 0.0000000000000000000000000000000000000000000006957 170.0
HKD2_k127_428095_8 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000001609 162.0
HKD2_k127_428095_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03574 - 3.6.1.55 0.0000000000000000000000000000000000000007367 154.0
HKD2_k127_431629_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 7.103e-313 976.0
HKD2_k127_431629_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 574.0
HKD2_k127_431629_10 lactoylglutathione lyase activity - - - 0.0001574 51.0
HKD2_k127_431629_2 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 439.0
HKD2_k127_431629_3 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 442.0
HKD2_k127_431629_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
HKD2_k127_431629_5 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000001498 120.0
HKD2_k127_431629_6 Peptidase family S49 K04773,K04774 - - 0.0000000000000000000004061 97.0
HKD2_k127_431629_7 Protein of unknown function (DUF3096) - - - 0.00000000001131 66.0
HKD2_k127_431629_8 - - - - 0.0000000000271 66.0
HKD2_k127_431629_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000004544 55.0
HKD2_k127_439748_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 531.0
HKD2_k127_439748_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000003495 87.0
HKD2_k127_439748_2 - - - - 0.0000000000000005485 78.0
HKD2_k127_4406995_0 carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 603.0
HKD2_k127_4406995_1 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 473.0
HKD2_k127_4406995_2 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - - 0.00000000000000000000000000000000000000000000003392 171.0
HKD2_k127_4406995_3 Thioredoxin domain - - - 0.0000000000000000000000000000000000004015 144.0
HKD2_k127_4406995_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000587 144.0
HKD2_k127_4406995_5 Thioesterase superfamily K01075 - 3.1.2.23 0.000000000000000000000000001412 117.0
HKD2_k127_4406995_6 DEAD DEAH box helicase K11927 - 3.6.4.13 0.0000000000000000000005592 101.0
HKD2_k127_4406995_7 permease K07089 - - 0.000000000000000001351 86.0
HKD2_k127_4409209_0 TIGRFAM cytochrome c oxidase accessory protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 8.981e-210 666.0
HKD2_k127_4409209_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 413.0
HKD2_k127_4409209_2 FixH - - - 0.00000000000000000000000000000000000002561 154.0
HKD2_k127_4463457_0 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.0 1171.0
HKD2_k127_4463457_1 Belongs to the thiolase family K00626 - 2.3.1.9 2.291e-211 663.0
HKD2_k127_4463457_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007381 282.0
HKD2_k127_4463457_11 Polyhydroxyalkanoate synthesis repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000105 258.0
HKD2_k127_4463457_12 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000000000000002331 218.0
HKD2_k127_4463457_13 Class II Aldolase and Adducin N-terminal domain K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.0000000000000000000000000000000000000000000000000000000000003919 228.0
HKD2_k127_4463457_14 Domain of unknown function (DUF4167) - - - 0.0000000000000000000000000000000000000000000000000000528 199.0
HKD2_k127_4463457_15 - - - - 0.000000000000000000000000000000000158 138.0
HKD2_k127_4463457_16 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000002631 111.0
HKD2_k127_4463457_2 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 565.0
HKD2_k127_4463457_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 560.0
HKD2_k127_4463457_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 525.0
HKD2_k127_4463457_5 KR domain K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 403.0
HKD2_k127_4463457_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 392.0
HKD2_k127_4463457_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 383.0
HKD2_k127_4463457_8 L-lactate dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 355.0
HKD2_k127_4463457_9 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 325.0
HKD2_k127_4528926_0 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 437.0
HKD2_k127_4528926_1 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 366.0
HKD2_k127_4528926_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000004228 156.0
HKD2_k127_4528926_11 PAS domain - - - 0.00000000000000000000000000000002334 137.0
HKD2_k127_4528926_13 - - - - 0.00000000843 61.0
HKD2_k127_4528926_14 - - - - 0.00000001362 64.0
HKD2_k127_4528926_15 TIGRFAM aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein K02051,K15553 - - 0.0002885 53.0
HKD2_k127_4528926_2 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 322.0
HKD2_k127_4528926_3 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 301.0
HKD2_k127_4528926_4 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 287.0
HKD2_k127_4528926_5 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006283 267.0
HKD2_k127_4528926_6 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 243.0
HKD2_k127_4528926_7 - - - - 0.00000000000000000000000000000000000000000000000000000003295 205.0
HKD2_k127_4528926_8 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000006582 176.0
HKD2_k127_4528926_9 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000007754 181.0
HKD2_k127_4570293_0 Aerotolerance regulator N-terminal - - - 0.0 1250.0
HKD2_k127_4570293_1 membrane - - - 0.0 1036.0
HKD2_k127_4570293_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004481 258.0
HKD2_k127_4570293_11 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000006923 144.0
HKD2_k127_4570293_12 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000005094 141.0
HKD2_k127_4570293_13 Protein of unknown function (DUF3297) - - - 0.000000000000000000000000000000000004589 139.0
HKD2_k127_4570293_14 PIN domain - - - 0.0000000000000000000000000000001005 128.0
HKD2_k127_4570293_15 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000785 120.0
HKD2_k127_4570293_16 HNH endonuclease - - - 0.000000000000000000000000004353 114.0
HKD2_k127_4570293_17 - - - - 0.0000000000000000000000001425 109.0
HKD2_k127_4570293_18 Nudix hydrolase - - - 0.000000000000000000000002494 103.0
HKD2_k127_4570293_19 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000005639 94.0
HKD2_k127_4570293_2 ATPase family associated with various cellular activities (AAA) K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 550.0
HKD2_k127_4570293_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 507.0
HKD2_k127_4570293_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 502.0
HKD2_k127_4570293_5 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 486.0
HKD2_k127_4570293_6 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 454.0
HKD2_k127_4570293_7 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 329.0
HKD2_k127_4570293_8 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007011 280.0
HKD2_k127_4570293_9 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002244 271.0
HKD2_k127_4661771_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0 1107.0
HKD2_k127_4661771_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 550.0
HKD2_k127_4661771_2 Aspartyl protease K06985 - - 0.000000000000000001413 90.0
HKD2_k127_4705392_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.237e-232 730.0
HKD2_k127_4705392_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 423.0
HKD2_k127_4705392_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 421.0
HKD2_k127_4705392_3 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101,K15054 - 1.1.2.3,1.1.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 381.0
HKD2_k127_4705392_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 353.0
HKD2_k127_4705392_5 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009925 270.0
HKD2_k127_4705392_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007288 259.0
HKD2_k127_4705392_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000000000000001733 244.0
HKD2_k127_4705392_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000001594 170.0
HKD2_k127_4770012_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 396.0
HKD2_k127_4770012_1 Domain of unknown function DUF87 K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 342.0
HKD2_k127_4770012_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004377 231.0
HKD2_k127_4770012_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000005573 119.0
HKD2_k127_4816916_0 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 623.0
HKD2_k127_4816916_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000001276 179.0
HKD2_k127_4847965_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 597.0
HKD2_k127_4847965_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 421.0
HKD2_k127_4847965_2 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000005836 189.0
HKD2_k127_4847965_3 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000002014 181.0
HKD2_k127_4847965_4 - - - - 0.000000000000000000001513 96.0
HKD2_k127_4847965_5 - - - - 0.000000000000000000169 91.0
HKD2_k127_4961264_0 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K02182 - 6.2.1.48 5.751e-298 920.0
HKD2_k127_4961264_1 Acetyl-coenzyme A synthetase N-terminus K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 509.0
HKD2_k127_4961264_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 343.0
HKD2_k127_4961264_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007157 283.0
HKD2_k127_4961264_4 small protein - - - 0.0000000000000001177 80.0
HKD2_k127_5047088_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
HKD2_k127_5047088_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007032 256.0
HKD2_k127_5047088_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000003336 175.0
HKD2_k127_5047088_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K09565 - 5.2.1.8 0.00000000000000000000000000000000000000007591 152.0
HKD2_k127_5060993_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.675e-250 784.0
HKD2_k127_5060993_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 517.0
HKD2_k127_5060993_2 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K01784,K03274 - 5.1.3.2,5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 506.0
HKD2_k127_5060993_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 461.0
HKD2_k127_5060993_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 457.0
HKD2_k127_5060993_5 heptosyltransferase K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 396.0
HKD2_k127_5060993_6 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 383.0
HKD2_k127_5060993_7 ABC transporter K06147,K11085 - - 0.000000000000000000000000002371 115.0
HKD2_k127_5114131_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1004.0
HKD2_k127_5114131_1 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 577.0
HKD2_k127_5114131_2 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 404.0
HKD2_k127_5114131_3 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
HKD2_k127_5114131_4 NifU-like N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004052 250.0
HKD2_k127_5114131_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000006033 192.0
HKD2_k127_5114131_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000000000000001047 162.0
HKD2_k127_5114131_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000001629 154.0
HKD2_k127_5114131_8 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000002641 110.0
HKD2_k127_5114131_9 membrane-associated protein K01077 - 3.1.3.1 0.0000000002562 72.0
HKD2_k127_5131472_0 inositol 2-dehydrogenase activity K18106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 586.0
HKD2_k127_5131472_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 561.0
HKD2_k127_5131472_10 ABC transporter K02051 - - 0.000000001057 70.0
HKD2_k127_5131472_11 Putative transposase of IS4/5 family (DUF4096) - - - 0.0002356 43.0
HKD2_k127_5131472_2 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 556.0
HKD2_k127_5131472_3 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 387.0
HKD2_k127_5131472_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 381.0
HKD2_k127_5131472_5 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 368.0
HKD2_k127_5131472_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 310.0
HKD2_k127_5131472_7 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 306.0
HKD2_k127_5131472_8 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001482 278.0
HKD2_k127_5131472_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000002585 86.0
HKD2_k127_5182912_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000003747 206.0
HKD2_k127_5182912_1 - - - - 0.00000000000000000000000000000000000000001837 154.0
HKD2_k127_5182912_2 - - - - 0.0000000000000000000000000000000000000001206 154.0
HKD2_k127_5182912_3 - - - - 0.00000000000000000003938 99.0
HKD2_k127_5182912_4 - - - - 0.0000002538 57.0
HKD2_k127_5245043_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1349.0
HKD2_k127_5245043_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006434 279.0
HKD2_k127_5245043_2 - - - - 0.0000003775 54.0
HKD2_k127_5245043_3 Thioredoxin - - - 0.000004785 48.0
HKD2_k127_5248500_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 461.0
HKD2_k127_5248500_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 380.0
HKD2_k127_5248500_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000001059 205.0
HKD2_k127_5248500_3 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000000000006486 147.0
HKD2_k127_5248500_4 N-terminal region of glycosyl transferase group 7 - - - 0.000000000000000000000000000001943 130.0
HKD2_k127_5248500_5 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.0000000000000000000000000002632 114.0
HKD2_k127_5248500_6 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000003261 103.0
HKD2_k127_5262484_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.618e-283 884.0
HKD2_k127_5262484_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 552.0
HKD2_k127_5262484_2 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 540.0
HKD2_k127_5262484_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184,K08358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 369.0
HKD2_k127_5262484_4 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
HKD2_k127_5262484_5 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000002886 216.0
HKD2_k127_5262484_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000001567 192.0
HKD2_k127_5262484_7 Part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000009053 155.0
HKD2_k127_5262484_8 - - - - 0.00000000000000000000000000000000000001087 153.0
HKD2_k127_5262484_9 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000002264 123.0
HKD2_k127_5265665_0 FtsX-like permease family - - - 1.017e-197 623.0
HKD2_k127_5265665_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 485.0
HKD2_k127_5265665_2 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 451.0
HKD2_k127_5265665_3 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 449.0
HKD2_k127_5265665_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 389.0
HKD2_k127_5265665_5 ABC-type tungstate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 340.0
HKD2_k127_5265665_6 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 322.0
HKD2_k127_5265665_7 - - - - 0.00004045 52.0
HKD2_k127_5265665_8 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0002314 52.0
HKD2_k127_5267224_0 GTP-binding protein TypA K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0 1035.0
HKD2_k127_5267224_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1019.0
HKD2_k127_5267224_10 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 464.0
HKD2_k127_5267224_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 457.0
HKD2_k127_5267224_12 HpcH/HpaI aldolase/citrate lyase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 427.0
HKD2_k127_5267224_13 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 436.0
HKD2_k127_5267224_14 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 422.0
HKD2_k127_5267224_15 PFAM regulatory protein LysR K11921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 419.0
HKD2_k127_5267224_16 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 419.0
HKD2_k127_5267224_17 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 392.0
HKD2_k127_5267224_18 outer membrane protein and related peptidoglycan-associated (Lipo)proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 389.0
HKD2_k127_5267224_19 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 364.0
HKD2_k127_5267224_2 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.992e-237 738.0
HKD2_k127_5267224_20 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 353.0
HKD2_k127_5267224_21 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 321.0
HKD2_k127_5267224_22 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 308.0
HKD2_k127_5267224_23 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 309.0
HKD2_k127_5267224_24 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 293.0
HKD2_k127_5267224_25 PAP2 superfamily K12978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001168 252.0
HKD2_k127_5267224_26 invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
HKD2_k127_5267224_27 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000001445 215.0
HKD2_k127_5267224_28 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000007936 189.0
HKD2_k127_5267224_29 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000005918 183.0
HKD2_k127_5267224_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 7.995e-205 643.0
HKD2_k127_5267224_30 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000004019 156.0
HKD2_k127_5267224_31 YGGT family K02221 - - 0.00000000000000000000000000000000000002969 146.0
HKD2_k127_5267224_32 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000006955 146.0
HKD2_k127_5267224_33 succinate dehydrogenase K00242 - - 0.0000000000000000000000000000000000009792 149.0
HKD2_k127_5267224_34 DUF167 K09131 - - 0.0000000000000000000000000000172 120.0
HKD2_k127_5267224_35 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000005392 99.0
HKD2_k127_5267224_37 - - - - 0.0000000000000000000006715 102.0
HKD2_k127_5267224_38 - - - - 0.000000000000000000001964 100.0
HKD2_k127_5267224_39 Cytochrome c - - - 0.0000000000000000114 85.0
HKD2_k127_5267224_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 9.557e-195 613.0
HKD2_k127_5267224_40 - - - - 0.000000000000002267 82.0
HKD2_k127_5267224_41 - - - - 0.0000000001638 68.0
HKD2_k127_5267224_43 TIGRFAM pentapeptide MXKDX repeat protein - - - 0.00001736 49.0
HKD2_k127_5267224_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 609.0
HKD2_k127_5267224_6 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 538.0
HKD2_k127_5267224_7 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 541.0
HKD2_k127_5267224_8 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 511.0
HKD2_k127_5267224_9 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 480.0
HKD2_k127_5270856_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 554.0
HKD2_k127_5270856_1 Dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 361.0
HKD2_k127_5270963_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 555.0
HKD2_k127_5270963_1 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 486.0
HKD2_k127_5270963_2 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 389.0
HKD2_k127_5270963_3 Hydrogenase expression formation protein (HypE) K04655,K07492,K08303 - - 0.000000000000007841 73.0
HKD2_k127_5275906_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 7.856e-241 754.0
HKD2_k127_5275906_1 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 471.0
HKD2_k127_5275906_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 301.0
HKD2_k127_5275906_3 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001447 241.0
HKD2_k127_5275906_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 236.0
HKD2_k127_5275906_5 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000006734 205.0
HKD2_k127_5275906_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000001269 164.0
HKD2_k127_5275906_7 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000009795 136.0
HKD2_k127_5276607_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.524e-313 968.0
HKD2_k127_5276607_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 3.469e-194 609.0
HKD2_k127_5276607_2 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 574.0
HKD2_k127_5276607_3 Phosphoglycerate kinase K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 554.0
HKD2_k127_5276607_4 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 347.0
HKD2_k127_5276607_5 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 327.0
HKD2_k127_5276607_6 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000001204 248.0
HKD2_k127_5276607_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000001476 87.0
HKD2_k127_5281625_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 377.0
HKD2_k127_5281625_1 4Fe-4S dicluster domain - - - 0.000000004842 61.0
HKD2_k127_5291126_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 3.778e-293 912.0
HKD2_k127_5291126_1 Acyl-CoA reductase (LuxC) K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 5.736e-289 892.0
HKD2_k127_5291126_10 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000002826 157.0
HKD2_k127_5291126_11 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000001896 160.0
HKD2_k127_5291126_2 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 7.227e-286 890.0
HKD2_k127_5291126_3 ABC transporter transmembrane region K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 4.791e-256 796.0
HKD2_k127_5291126_4 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 1.195e-194 613.0
HKD2_k127_5291126_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 553.0
HKD2_k127_5291126_6 lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 421.0
HKD2_k127_5291126_7 CDP-alcohol phosphatidyltransferase K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 387.0
HKD2_k127_5291126_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 368.0
HKD2_k127_5291126_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 325.0
HKD2_k127_5294722_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 6.122e-278 863.0
HKD2_k127_5294722_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 9.198e-252 779.0
HKD2_k127_5294722_2 Protein of unknown function (DUF2865) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 327.0
HKD2_k127_5294722_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000003524 165.0
HKD2_k127_5339917_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004602 287.0
HKD2_k127_5339917_1 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000000001356 235.0
HKD2_k127_5339917_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000846 122.0
HKD2_k127_5339917_3 Bacterial protein of unknown function (DUF898) - - - 0.0007843 43.0
HKD2_k127_5340154_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 351.0
HKD2_k127_5340154_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 334.0
HKD2_k127_5352416_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 441.0
HKD2_k127_5352416_1 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 415.0
HKD2_k127_5352416_2 Membrane fusogenic activity K09806 - - 0.0000000000000000000000008919 104.0
HKD2_k127_5352416_3 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000008287 57.0
HKD2_k127_5357357_0 ATPases associated with a variety of cellular activities K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 580.0
HKD2_k127_5357357_1 Disulfide bond formation protein DsbB K03611 - - 0.000000000000000000000000000000000000000000000002838 181.0
HKD2_k127_5357357_2 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000005697 172.0
HKD2_k127_5378053_0 enoyl-CoA hydratase isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.849e-240 753.0
HKD2_k127_5378053_1 Cupin 2, conserved barrel - - - 0.00000000000000000000000000008703 117.0
HKD2_k127_5383129_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 611.0
HKD2_k127_5383129_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 508.0
HKD2_k127_5383129_2 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 337.0
HKD2_k127_5383129_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
HKD2_k127_5383129_4 DJ-1/PfpI family K18199 - 4.2.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
HKD2_k127_5383129_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005646 245.0
HKD2_k127_5383129_6 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002322 252.0
HKD2_k127_5383129_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000964 214.0
HKD2_k127_5383129_8 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000001272 204.0
HKD2_k127_5383129_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000001652 200.0
HKD2_k127_5402845_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 5.597e-263 815.0
HKD2_k127_5402845_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 421.0
HKD2_k127_5402845_2 - K01992 - - 0.0000000000000000000000000000000000005284 147.0
HKD2_k127_5402845_3 Excinuclease ABC, C subunit K07461 - - 0.000000000000000000000000000000000044 136.0
HKD2_k127_5402845_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000001262 141.0
HKD2_k127_5409291_0 Transcriptional regulatory protein, C terminal K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 451.0
HKD2_k127_5409291_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 453.0
HKD2_k127_5409291_10 - - - - 0.0000000000000000000000002284 106.0
HKD2_k127_5409291_11 - - - - 0.00000000000000000000002532 109.0
HKD2_k127_5409291_12 Histidine kinase K03407 - 2.7.13.3 0.000000000000000008728 91.0
HKD2_k127_5409291_13 Protein of unknown function (DUF465) - - - 0.00000000002376 66.0
HKD2_k127_5409291_14 Protein of unknown function (DUF3606) - - - 0.000001627 52.0
HKD2_k127_5409291_2 Pfam Transposase IS66 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 420.0
HKD2_k127_5409291_3 Protein of unknown function (DUF1134) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 291.0
HKD2_k127_5409291_4 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001357 267.0
HKD2_k127_5409291_5 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000008306 259.0
HKD2_k127_5409291_6 Flagellar FliJ protein - - - 0.0000000000000000000000000000000000000000000000000000002687 196.0
HKD2_k127_5409291_7 Function of homologous gene experimentally demonstrated in an other organism K03407 - 2.7.13.3 0.0000000000000000000000000000000000000057 150.0
HKD2_k127_5409291_8 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000002363 138.0
HKD2_k127_5409291_9 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000009913 122.0
HKD2_k127_5433388_0 Apolipoprotein A1/A4/E domain - - - 1.369e-298 969.0
HKD2_k127_5433388_1 Protein conserved in bacteria K09989 - - 4.526e-212 663.0
HKD2_k127_5433388_10 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000004826 192.0
HKD2_k127_5433388_11 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000000000000001223 188.0
HKD2_k127_5433388_12 - - - - 0.0000000000000000000000000000000000002833 151.0
HKD2_k127_5433388_13 ChaB K06197 - - 0.00000000000000000000000003727 110.0
HKD2_k127_5433388_14 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000001141 98.0
HKD2_k127_5433388_15 Domain of unknown function (DUF4410) - - - 0.0000000004015 70.0
HKD2_k127_5433388_16 Histidine Phosphotransfer domain - - - 0.000000001587 68.0
HKD2_k127_5433388_17 - - - - 0.000000006463 58.0
HKD2_k127_5433388_19 - - - - 0.0000002533 60.0
HKD2_k127_5433388_2 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 605.0
HKD2_k127_5433388_20 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.00003364 46.0
HKD2_k127_5433388_3 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 533.0
HKD2_k127_5433388_4 FAD dependent oxidoreductase K04755,K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 466.0
HKD2_k127_5433388_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 375.0
HKD2_k127_5433388_6 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 317.0
HKD2_k127_5433388_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 259.0
HKD2_k127_5433388_8 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000008843 227.0
HKD2_k127_5433388_9 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000002905 222.0
HKD2_k127_5440974_0 Transglycosylase SLT domain K08309 - - 9.545e-221 702.0
HKD2_k127_5466625_0 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 584.0
HKD2_k127_5466625_1 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 537.0
HKD2_k127_5466625_2 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 287.0
HKD2_k127_5466625_3 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000000000000000000000000000004722 166.0
HKD2_k127_5483377_0 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 563.0
HKD2_k127_5483377_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 456.0
HKD2_k127_5483377_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 391.0
HKD2_k127_5483377_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 316.0
HKD2_k127_550172_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.88e-232 727.0
HKD2_k127_550172_1 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 486.0
HKD2_k127_550172_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 444.0
HKD2_k127_550172_3 S4 RNA-binding domain K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 365.0
HKD2_k127_550172_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001013 282.0
HKD2_k127_550172_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002486 277.0
HKD2_k127_550172_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000006909 230.0
HKD2_k127_550172_7 - - - - 0.000000000000000000257 89.0
HKD2_k127_5532200_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K02229 - 1.14.13.83,1.7.7.1 2.55e-265 835.0
HKD2_k127_5532200_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 1.214e-243 762.0
HKD2_k127_5532200_2 Formate/nitrite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 355.0
HKD2_k127_5532200_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 267.0
HKD2_k127_5532200_4 Domain of unknown function (DUF1993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000161 235.0
HKD2_k127_5532200_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000002433 138.0
HKD2_k127_5575594_0 DNA polymerase K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 1.424e-286 890.0
HKD2_k127_5575594_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 551.0
HKD2_k127_5575594_10 Bacterial extracellular solute-binding protein - - - 0.0000000000007893 79.0
HKD2_k127_5575594_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 539.0
HKD2_k127_5575594_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 462.0
HKD2_k127_5575594_4 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 459.0
HKD2_k127_5575594_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 380.0
HKD2_k127_5575594_6 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 363.0
HKD2_k127_5575594_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 322.0
HKD2_k127_5575594_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD2_k127_5575594_9 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000006671 261.0
HKD2_k127_5579789_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 3.06e-308 969.0
HKD2_k127_5579789_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 GO:0000166,GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016667,GO:0016668,GO:0032553,GO:0032991,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.8.1.2 1.873e-261 819.0
HKD2_k127_5579789_2 Sulfite reductase K00381,K00392 - 1.8.1.2,1.8.7.1 3.657e-242 755.0
HKD2_k127_5579789_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04109,K11178 - 1.17.1.4,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000959 240.0
HKD2_k127_5579789_4 [2Fe-2S] binding domain K04107 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000004329 222.0
HKD2_k127_5579789_5 - - - - 0.00000000000000000000000000000000000000003545 160.0
HKD2_k127_5579789_6 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000000000000003466 142.0
HKD2_k127_55916_0 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 6.935e-216 683.0
HKD2_k127_55916_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 331.0
HKD2_k127_55916_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000002783 172.0
HKD2_k127_55916_3 Peptidase family M28 - - - 0.0000002358 59.0
HKD2_k127_5726460_0 Dehydratase family K01687 - 4.2.1.9 2.537e-285 886.0
HKD2_k127_5726460_1 NAD-dependent epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 403.0
HKD2_k127_5726460_2 C-methyltransferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 357.0
HKD2_k127_5726460_3 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000001259 211.0
HKD2_k127_5746678_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1211.0
HKD2_k127_5746678_1 Monomeric isocitrate dehydrogenase - - - 0.0 1201.0
HKD2_k127_5746678_10 ThiS family - - - 0.000000000000000001563 89.0
HKD2_k127_5746678_2 SpoU rRNA Methylase family K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 556.0
HKD2_k127_5746678_3 PFAM SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 501.0
HKD2_k127_5746678_4 COG1226 Kef-type K transport systems K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 483.0
HKD2_k127_5746678_5 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 434.0
HKD2_k127_5746678_6 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000001846 215.0
HKD2_k127_5746678_7 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000000000001113 143.0
HKD2_k127_5746678_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000424 138.0
HKD2_k127_5746678_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000003107 136.0
HKD2_k127_5792805_0 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 581.0
HKD2_k127_5792805_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 453.0
HKD2_k127_5792805_2 NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 422.0
HKD2_k127_5792805_3 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 372.0
HKD2_k127_5798231_0 Aminotransferase class I and II - - - 2.302e-217 679.0
HKD2_k127_5798231_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 310.0
HKD2_k127_5798231_2 Dehydrogenase K16422 - 1.1.3.46 0.000000000000000000000000004066 113.0
HKD2_k127_5822787_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 467.0
HKD2_k127_5822787_1 mandelate racemase muconate lactonizing K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 424.0
HKD2_k127_5822787_2 ATPases associated with a variety of cellular activities K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 392.0
HKD2_k127_5822787_3 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006538 269.0
HKD2_k127_5822787_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000000000002684 163.0
HKD2_k127_5822787_5 - - - - 0.0000000000000000000000000001504 118.0
HKD2_k127_5832598_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 500.0
HKD2_k127_5832598_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 454.0
HKD2_k127_5832598_2 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 357.0
HKD2_k127_5832598_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 311.0
HKD2_k127_5832598_4 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.0000000000000000000000000000000000000000000003546 171.0
HKD2_k127_5832598_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000003269 129.0
HKD2_k127_5867671_0 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 9.639e-198 626.0
HKD2_k127_5867671_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 531.0
HKD2_k127_5867671_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 486.0
HKD2_k127_5867671_3 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 483.0
HKD2_k127_5867671_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000004911 202.0
HKD2_k127_5867671_5 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000001184 86.0
HKD2_k127_5867671_6 transferase activity, transferring glycosyl groups K20999 - - 0.00003714 49.0
HKD2_k127_5888871_0 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 517.0
HKD2_k127_5888871_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 514.0
HKD2_k127_5888871_2 Electron transfer flavoprotein domain K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 420.0
HKD2_k127_5888871_3 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 291.0
HKD2_k127_5888871_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002809 271.0
HKD2_k127_5896216_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 501.0
HKD2_k127_5896216_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000008036 172.0
HKD2_k127_5896216_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000001656 172.0
HKD2_k127_5957426_0 Putative nucleotidyltransferase substrate binding domain K02342,K07182 - 2.7.7.7 8.92e-240 760.0
HKD2_k127_5957426_1 5-aminolevulinic acid synthase K00643 - 2.3.1.37 9.468e-230 715.0
HKD2_k127_5957426_2 Transition state regulatory protein AbrB K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002315 283.0
HKD2_k127_5957426_3 Oxidoreductase family, C-terminal alpha beta domain - - - 0.00000000000000000000000000000000000000000000000000000003072 209.0
HKD2_k127_5957426_4 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000001264 169.0
HKD2_k127_5957426_5 - - - - 0.00000000168 59.0
HKD2_k127_5974494_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1126.0
HKD2_k127_5974494_1 Beta-Casp domain K07576 - - 8.714e-262 813.0
HKD2_k127_5974494_2 undecaprenol kinase activity K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000000000000000002447 117.0
HKD2_k127_5976066_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 3.829e-217 696.0
HKD2_k127_5976066_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 349.0
HKD2_k127_5976066_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K22209 - 4.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000001552 265.0
HKD2_k127_606708_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1374.0
HKD2_k127_606708_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 0.0 1235.0
HKD2_k127_606708_10 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 522.0
HKD2_k127_606708_11 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 502.0
HKD2_k127_606708_12 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 495.0
HKD2_k127_606708_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04109,K11178 - 1.17.1.4,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 441.0
HKD2_k127_606708_14 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
HKD2_k127_606708_15 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 399.0
HKD2_k127_606708_16 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 367.0
HKD2_k127_606708_17 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 331.0
HKD2_k127_606708_18 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 342.0
HKD2_k127_606708_19 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
HKD2_k127_606708_2 benzoyl-CoA reductase K04113 - 1.3.7.8 9.178e-244 758.0
HKD2_k127_606708_20 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000000000000000004527 220.0
HKD2_k127_606708_21 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000001141 192.0
HKD2_k127_606708_22 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000006093 186.0
HKD2_k127_606708_23 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000001525 161.0
HKD2_k127_606708_24 ferredoxin - - - 0.00000000000000000000000000000000000001816 144.0
HKD2_k127_606708_25 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000008253 147.0
HKD2_k127_606708_26 transcriptional regulator - - - 0.0000000000000000000000000000000000008323 145.0
HKD2_k127_606708_27 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000003199 131.0
HKD2_k127_606708_28 Rubrerythrin - - - 0.0000000000000000000000000001299 130.0
HKD2_k127_606708_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.054e-231 726.0
HKD2_k127_606708_4 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 4.771e-227 709.0
HKD2_k127_606708_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00179 - 1.2.7.8 9.788e-210 655.0
HKD2_k127_606708_6 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.419e-203 649.0
HKD2_k127_606708_7 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 605.0
HKD2_k127_606708_8 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 593.0
HKD2_k127_606708_9 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 589.0
HKD2_k127_6108013_0 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1388.0
HKD2_k127_6108013_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1278.0
HKD2_k127_6108013_10 response regulator K11443 - - 0.000000000000000000000000000000000000000000000000000000000000000000009335 237.0
HKD2_k127_6108013_11 PFAM AzlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
HKD2_k127_6108013_12 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000000000000000003436 222.0
HKD2_k127_6108013_13 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000000000000001386 209.0
HKD2_k127_6108013_14 - K09004 - - 0.00000000000000000000000000000000000000000000002515 174.0
HKD2_k127_6108013_15 Branched-chain amino acid transport - - - 0.000000000000000000000000000000001676 137.0
HKD2_k127_6108013_16 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000000000000000002363 123.0
HKD2_k127_6108013_17 Protein of unknown function (DUF3572) - - - 0.00000000000000000163 88.0
HKD2_k127_6108013_18 Ribosomal protein L33 K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001812 86.0
HKD2_k127_6108013_19 DDE superfamily endonuclease K07492 - - 0.0000000000000001028 79.0
HKD2_k127_6108013_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 6.534e-319 992.0
HKD2_k127_6108013_20 Putative Flp pilus-assembly TadE/G-like - - - 0.000000008711 59.0
HKD2_k127_6108013_21 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0009594 44.0
HKD2_k127_6108013_3 Response regulator receiver K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 591.0
HKD2_k127_6108013_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 552.0
HKD2_k127_6108013_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 520.0
HKD2_k127_6108013_6 Domain of unknown function (DUF1849) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 307.0
HKD2_k127_6108013_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
HKD2_k127_6108013_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002136 269.0
HKD2_k127_6108013_9 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003852 247.0
HKD2_k127_6151798_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1480.0
HKD2_k127_6151798_1 Aminotransferase class-III K00822 - 2.6.1.18 8.009e-225 704.0
HKD2_k127_6151798_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 351.0
HKD2_k127_6151798_11 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 347.0
HKD2_k127_6151798_12 ATPases associated with a variety of cellular activities K02003,K05685,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 319.0
HKD2_k127_6151798_13 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000001837 238.0
HKD2_k127_6151798_14 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000002888 220.0
HKD2_k127_6151798_15 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000808 205.0
HKD2_k127_6151798_16 Response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000002773 188.0
HKD2_k127_6151798_17 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000000000000001124 187.0
HKD2_k127_6151798_18 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000021 178.0
HKD2_k127_6151798_19 - - - - 0.0000000000000000000000000000000008396 140.0
HKD2_k127_6151798_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 2.485e-209 660.0
HKD2_k127_6151798_21 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00000748 52.0
HKD2_k127_6151798_22 Bacterial protein of unknown function (DUF883) - - - 0.00001269 52.0
HKD2_k127_6151798_3 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 559.0
HKD2_k127_6151798_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 537.0
HKD2_k127_6151798_5 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 499.0
HKD2_k127_6151798_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 500.0
HKD2_k127_6151798_7 Peptidase M16 inactive domain K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 482.0
HKD2_k127_6151798_8 Putative diguanylate phosphodiesterase K13593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 427.0
HKD2_k127_6151798_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 377.0
HKD2_k127_6181741_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 422.0
HKD2_k127_6181741_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001163 239.0
HKD2_k127_6181741_2 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000002115 229.0
HKD2_k127_6181741_3 Protein conserved in bacteria - - - 0.0000000000000000000000000001942 115.0
HKD2_k127_6208673_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 1.087e-262 820.0
HKD2_k127_6208673_1 Fumarate hydratase (Fumerase) K01677,K03779 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 564.0
HKD2_k127_6208673_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 338.0
HKD2_k127_6208673_3 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K03780 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008773 284.0
HKD2_k127_6208673_4 succinate dehydrogenase K00246 - - 0.000000000000000000000000000000744 127.0
HKD2_k127_6208673_5 succinate dehydrogenase K00247 - - 0.0000000000000000000000000008741 117.0
HKD2_k127_6289766_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 613.0
HKD2_k127_6289766_1 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 340.0
HKD2_k127_6289766_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 313.0
HKD2_k127_6289766_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 291.0
HKD2_k127_6289766_4 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118,K10237 - - 0.0000000000000000000000000000000000000000000000000002503 197.0
HKD2_k127_6289766_5 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000006221 138.0
HKD2_k127_6289766_6 methionine synthase K00548 - 2.1.1.13 0.000000000000000001497 95.0
HKD2_k127_6289766_7 binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000007678 66.0
HKD2_k127_6289766_8 Glutaminase K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.00008226 45.0
HKD2_k127_6367754_0 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 305.0
HKD2_k127_6367754_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000002856 165.0
HKD2_k127_6367754_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000003241 160.0
HKD2_k127_6422183_0 Carbamoyl-phosphate synthase L chain K01968 - 6.4.1.4 2.983e-231 730.0
HKD2_k127_6422183_1 - - - - 0.00000000000000000000000000001164 129.0
HKD2_k127_6423490_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 554.0
HKD2_k127_6423490_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000448 247.0
HKD2_k127_6423490_2 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000006704 151.0
HKD2_k127_6423490_3 - - - - 0.0000000000000000000253 93.0
HKD2_k127_6423490_4 - - - - 0.000000000007344 71.0
HKD2_k127_6424900_0 Amidohydrolase family K01465 - 3.5.2.3 1.336e-216 679.0
HKD2_k127_6424900_1 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 5.785e-197 622.0
HKD2_k127_6424900_2 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 313.0
HKD2_k127_6424900_3 Protein of unknown function (DUF2385) - - - 0.000000000000000000000000000000000000000000000000000002911 195.0
HKD2_k127_6424900_4 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000016 179.0
HKD2_k127_6424900_5 - - - - 0.0000000000000000000000000000000000000003798 153.0
HKD2_k127_6424900_6 - - - - 0.00000000000000000000000000001312 120.0
HKD2_k127_6424900_7 Belongs to the GcvT family K06980 - - 0.0000000000000000000000167 102.0
HKD2_k127_6425175_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 2.175e-219 695.0
HKD2_k127_6425175_1 protein involved in outer membrane biogenesis K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001513 302.0
HKD2_k127_6425175_2 Stringent starvation protein B K09985 - - 0.0000000000000000000000000000000000000000000000000000003078 201.0
HKD2_k127_6425175_3 Ribbon-helix-helix domain - - - 0.000000000000000000000000000005435 124.0
HKD2_k127_6425175_5 Domain of unknown function (DUF4169) - - - 0.00007484 49.0
HKD2_k127_6427809_0 Carboxyl transferase domain K01969 - 6.4.1.4 6.398e-274 852.0
HKD2_k127_6427809_1 FAD dependent oxidoreductase K13796 - - 8.341e-235 734.0
HKD2_k127_6427809_10 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007128 265.0
HKD2_k127_6427809_11 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006411 255.0
HKD2_k127_6427809_12 Putative vitamin uptake transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008371 252.0
HKD2_k127_6427809_13 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000002769 212.0
HKD2_k127_6427809_14 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.00000000000000000000000000000000000000000000000000000000001441 216.0
HKD2_k127_6427809_15 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000009825 177.0
HKD2_k127_6427809_16 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000003861 132.0
HKD2_k127_6427809_17 Protein of unknown function (DUF1236) - - - 0.0000000000000000000000000001281 123.0
HKD2_k127_6427809_18 Sulfotransferase domain - - - 0.000000000000000000006787 98.0
HKD2_k127_6427809_19 CsbD-like - - - 0.00000000000005093 75.0
HKD2_k127_6427809_2 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 492.0
HKD2_k127_6427809_20 Sulfotransferase domain - - - 0.000000009546 57.0
HKD2_k127_6427809_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 422.0
HKD2_k127_6427809_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 398.0
HKD2_k127_6427809_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 386.0
HKD2_k127_6427809_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 381.0
HKD2_k127_6427809_7 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 344.0
HKD2_k127_6427809_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 326.0
HKD2_k127_6427809_9 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001101 278.0
HKD2_k127_6454340_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 3.635e-233 734.0
HKD2_k127_6454340_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 432.0
HKD2_k127_6454340_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000009207 171.0
HKD2_k127_6462488_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 1.717e-209 657.0
HKD2_k127_6462488_1 ABC transporter substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 499.0
HKD2_k127_6462488_10 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000005968 123.0
HKD2_k127_6462488_11 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.0000000000007322 73.0
HKD2_k127_6462488_12 Flp Fap pilin component K02651 - - 0.00000008262 57.0
HKD2_k127_6462488_2 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 416.0
HKD2_k127_6462488_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 389.0
HKD2_k127_6462488_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 369.0
HKD2_k127_6462488_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 346.0
HKD2_k127_6462488_6 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 333.0
HKD2_k127_6462488_7 NUDIX domain K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000004054 215.0
HKD2_k127_6462488_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000003253 212.0
HKD2_k127_6462488_9 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000000000000001913 197.0
HKD2_k127_6467876_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 1.138e-270 847.0
HKD2_k127_6467876_1 Receptor family ligand binding region K01999 - - 1.408e-197 621.0
HKD2_k127_6467876_10 Amidohydrolase K03392 - 4.1.1.45 0.0001126 50.0
HKD2_k127_6467876_2 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 525.0
HKD2_k127_6467876_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 480.0
HKD2_k127_6467876_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 468.0
HKD2_k127_6467876_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 362.0
HKD2_k127_6467876_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 359.0
HKD2_k127_6467876_7 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 327.0
HKD2_k127_6467876_8 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002413 282.0
HKD2_k127_6467876_9 phenylacetic acid degradation protein paaD K02614 - - 0.0000000000000000000000000000000000000000013 170.0
HKD2_k127_6479061_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.839e-221 705.0
HKD2_k127_6479061_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.428e-219 685.0
HKD2_k127_6479061_10 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000004437 131.0
HKD2_k127_6479061_11 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00001516 49.0
HKD2_k127_6479061_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 557.0
HKD2_k127_6479061_3 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 528.0
HKD2_k127_6479061_4 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 436.0
HKD2_k127_6479061_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 290.0
HKD2_k127_6479061_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
HKD2_k127_6479061_7 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000436 235.0
HKD2_k127_6479061_8 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000003082 204.0
HKD2_k127_6479061_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000008755 171.0
HKD2_k127_6496810_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 6.817e-217 679.0
HKD2_k127_6496810_1 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 1.955e-195 619.0
HKD2_k127_6496810_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 452.0
HKD2_k127_6496810_3 Diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 370.0
HKD2_k127_6496810_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000399 256.0
HKD2_k127_6496810_5 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000002888 195.0
HKD2_k127_6496810_6 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000002211 177.0
HKD2_k127_6496810_7 methyltransferase activity - - - 0.00000000000000000000000000000000000004474 148.0
HKD2_k127_6496810_8 TfoX N-terminal domain K07343 - - 0.00000000000000000000000000000104 124.0
HKD2_k127_6496810_9 Diguanylate cyclase K13590 - 2.7.7.65 0.00000002573 58.0
HKD2_k127_6503842_0 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 490.0
HKD2_k127_6503842_1 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 453.0
HKD2_k127_6503842_2 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 427.0
HKD2_k127_6503842_3 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 407.0
HKD2_k127_6503842_4 Acetyltransferase (GNAT) domain K03827 - - 0.000000000000000000000000000000000000000000000000000000000000005016 221.0
HKD2_k127_6503842_5 Protein of unknown function (DUF4031) - - - 0.000000000000000000000000000007584 124.0
HKD2_k127_6520981_0 Sugar (and other) transporter K08369 - - 4.722e-245 762.0
HKD2_k127_6520981_1 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 8.061e-195 616.0
HKD2_k127_6520981_10 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000001514 205.0
HKD2_k127_6520981_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000004271 186.0
HKD2_k127_6520981_12 SAF K02279 - - 0.00000000000000000000000000000000000000000000000002423 183.0
HKD2_k127_6520981_13 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000002794 169.0
HKD2_k127_6520981_14 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000001925 151.0
HKD2_k127_6520981_15 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000001046 106.0
HKD2_k127_6520981_16 Pilus assembly protein CpaB K02279 - - 0.0000001154 60.0
HKD2_k127_6520981_17 PFAM Cupin 2, conserved barrel K14673 - - 0.00007948 54.0
HKD2_k127_6520981_2 Major facilitator Superfamily K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 462.0
HKD2_k127_6520981_3 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 395.0
HKD2_k127_6520981_4 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 354.0
HKD2_k127_6520981_5 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
HKD2_k127_6520981_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 297.0
HKD2_k127_6520981_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
HKD2_k127_6520981_8 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000355 226.0
HKD2_k127_6520981_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
HKD2_k127_6532913_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 507.0
HKD2_k127_6532913_1 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 416.0
HKD2_k127_6533657_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1272.0
HKD2_k127_6533657_1 FAD linked oxidases, C-terminal domain K00004,K00102 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4 2.91e-228 715.0
HKD2_k127_6533657_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000006528 200.0
HKD2_k127_6533657_11 Transposase K07497 - - 0.000000000000000000000000000000000009673 137.0
HKD2_k127_6533657_12 AAA ATPase domain - - - 0.00000000000000000000000000000001642 144.0
HKD2_k127_6533657_13 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000000000006879 129.0
HKD2_k127_6533657_2 IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 561.0
HKD2_k127_6533657_3 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 536.0
HKD2_k127_6533657_4 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 508.0
HKD2_k127_6533657_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 422.0
HKD2_k127_6533657_6 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 407.0
HKD2_k127_6533657_7 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 357.0
HKD2_k127_6533657_8 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002282 263.0
HKD2_k127_6533657_9 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000006484 208.0
HKD2_k127_6583294_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1568.0
HKD2_k127_6583294_1 Glycosyl transferase family 21 K00694,K01210 - 2.4.1.12,3.2.1.58 0.0 1285.0
HKD2_k127_6583294_10 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000000000000000001983 155.0
HKD2_k127_6583294_11 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000003246 123.0
HKD2_k127_6583294_12 Tfp pilus assembly protein FimV - - - 0.00000000000004718 81.0
HKD2_k127_6583294_13 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.00000008438 53.0
HKD2_k127_6583294_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 4.727e-315 986.0
HKD2_k127_6583294_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.272e-301 934.0
HKD2_k127_6583294_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 586.0
HKD2_k127_6583294_5 beta (1-6) glucans synthase K01210 - 3.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 579.0
HKD2_k127_6583294_6 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 317.0
HKD2_k127_6583294_7 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 308.0
HKD2_k127_6583294_8 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 299.0
HKD2_k127_6583294_9 - - - - 0.000000000000000000000000000000000000000000000000002106 188.0
HKD2_k127_6597620_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1187.0
HKD2_k127_6597620_1 LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 388.0
HKD2_k127_6597620_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 366.0
HKD2_k127_6612064_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.806e-274 848.0
HKD2_k127_6612064_1 SnoaL-like polyketide cyclase K06893 - - 0.00000000000000001167 90.0
HKD2_k127_6612064_2 - - - - 0.000000000000002943 80.0
HKD2_k127_6612064_3 - - - - 0.00000000264 66.0
HKD2_k127_6612064_5 Belongs to the 4-oxalocrotonate tautomerase family K01821 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 0.0009028 47.0
HKD2_k127_66661_0 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 350.0
HKD2_k127_66661_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006869 270.0
HKD2_k127_66661_2 Zinc-finger domain - - - 0.000000000000000000000000000000003187 142.0
HKD2_k127_66661_3 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000001573 77.0
HKD2_k127_6674317_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835 - 5.4.2.2 4.413e-243 756.0
HKD2_k127_6674317_1 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.000000000000000000000000000103 116.0
HKD2_k127_6716767_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007706 273.0
HKD2_k127_6716767_1 Glutathione S-transferase, N-terminal domain K01800 - 5.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001647 252.0
HKD2_k127_6716767_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000001536 203.0
HKD2_k127_6716767_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000001707 115.0
HKD2_k127_6834185_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.956e-267 827.0
HKD2_k127_6834185_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 376.0
HKD2_k127_6834185_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 341.0
HKD2_k127_6834185_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007719 207.0
HKD2_k127_6834185_4 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000007659 203.0
HKD2_k127_6834185_5 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000002953 144.0
HKD2_k127_6834185_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000002362 126.0
HKD2_k127_6834185_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000001886 106.0
HKD2_k127_6834185_8 - - - - 0.000000001674 62.0
HKD2_k127_6843384_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 589.0
HKD2_k127_6843384_1 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000001286 199.0
HKD2_k127_6848524_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.274e-230 719.0
HKD2_k127_6848524_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 544.0
HKD2_k127_6848524_10 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000003876 55.0
HKD2_k127_6848524_11 Integrase - - - 0.0000005215 51.0
HKD2_k127_6848524_2 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 384.0
HKD2_k127_6848524_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001475 246.0
HKD2_k127_6848524_4 Protein of unknown function (DUF1036) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
HKD2_k127_6848524_5 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000005082 239.0
HKD2_k127_6848524_6 Protein of unknown function (DUF1244) K09948 - - 0.00000000000000000000000000000000000000000002858 164.0
HKD2_k127_6848524_7 Peptidoglycan-binding domain 1 K21470 - - 0.000000000000000000000000000000000001018 153.0
HKD2_k127_6848524_8 Belongs to the UPF0335 family - - - 0.000000000000000000000000000000000004221 139.0
HKD2_k127_6848524_9 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001089 74.0
HKD2_k127_6858487_0 Transglycosylase - - - 6.551e-206 656.0
HKD2_k127_6878191_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 505.0
HKD2_k127_6878191_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 402.0
HKD2_k127_6878191_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 381.0
HKD2_k127_6878191_3 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 355.0
HKD2_k127_6878191_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 349.0
HKD2_k127_6878191_5 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 339.0
HKD2_k127_6878191_6 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 308.0
HKD2_k127_6892219_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.891e-209 669.0
HKD2_k127_6892219_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 285.0
HKD2_k127_6892219_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002734 248.0
HKD2_k127_6892219_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002981 237.0
HKD2_k127_6892219_4 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000006021 226.0
HKD2_k127_6894317_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 413.0
HKD2_k127_6894317_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 301.0
HKD2_k127_6894317_2 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000003235 214.0
HKD2_k127_6894317_3 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000002875 204.0
HKD2_k127_6894317_4 - - - - 0.0000000003963 63.0
HKD2_k127_6926983_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 561.0
HKD2_k127_6926983_1 glycosyl transferase - - - 0.0000000000000000000000000000000000001424 147.0
HKD2_k127_693745_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.729e-229 717.0
HKD2_k127_693745_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 355.0
HKD2_k127_693745_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000002184 133.0
HKD2_k127_6945146_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 468.0
HKD2_k127_6945146_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 434.0
HKD2_k127_6945146_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 413.0
HKD2_k127_6945146_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 347.0
HKD2_k127_6945146_4 Thioesterase - - - 0.0000000000000000000000000000000000000001318 154.0
HKD2_k127_6945146_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000001544 115.0
HKD2_k127_6964196_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004168 274.0
HKD2_k127_6964196_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000003352 106.0
HKD2_k127_7000684_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 368.0
HKD2_k127_7000684_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000001456 167.0
HKD2_k127_7018046_0 Prokaryotic glutathione synthetase, N-terminal domain K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 509.0
HKD2_k127_7018046_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000004326 235.0
HKD2_k127_7018046_2 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000003655 142.0
HKD2_k127_7018046_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000009748 81.0
HKD2_k127_7018046_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000005617 77.0
HKD2_k127_7018046_5 His Kinase A (phosphoacceptor) domain - - - 0.00000002131 61.0
HKD2_k127_7018046_6 methyl-accepting chemotaxis protein - - - 0.0007856 46.0
HKD2_k127_7039618_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.274e-277 860.0
HKD2_k127_7039618_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.335e-271 843.0
HKD2_k127_7039618_10 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000009657 238.0
HKD2_k127_7039618_11 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000002047 228.0
HKD2_k127_7039618_12 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000002085 214.0
HKD2_k127_7039618_13 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000006578 165.0
HKD2_k127_7039618_14 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000005856 114.0
HKD2_k127_7039618_15 Diguanylate cyclase - - - 0.00000000000000000000000001442 111.0
HKD2_k127_7039618_16 - - - - 0.0000003626 54.0
HKD2_k127_7039618_2 Cys/Met metabolism PLP-dependent enzyme K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 3.106e-235 732.0
HKD2_k127_7039618_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 556.0
HKD2_k127_7039618_4 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 387.0
HKD2_k127_7039618_5 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 380.0
HKD2_k127_7039618_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 321.0
HKD2_k127_7039618_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 288.0
HKD2_k127_7039618_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004039 264.0
HKD2_k127_7039618_9 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003064 266.0
HKD2_k127_7042656_0 Histidine kinase K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 478.0
HKD2_k127_7042656_1 HPr Serine kinase C-terminal domain K06023 - - 0.00000000000000000000000000000000000004117 147.0
HKD2_k127_7042656_2 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000006149 79.0
HKD2_k127_7087737_0 Respiratory-chain NADH dehydrogenase 51 Kd subunit K00122,K00124,K00335 - 1.17.1.9,1.6.5.3 1.73e-253 792.0
HKD2_k127_7087737_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000002253 109.0
HKD2_k127_7152833_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.058e-253 790.0
HKD2_k127_7152833_1 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 1.056e-234 746.0
HKD2_k127_7152833_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 501.0
HKD2_k127_7152833_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 361.0
HKD2_k127_7152833_4 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.0000000000000000000000000000000000000000000000000000000000001695 215.0
HKD2_k127_7152833_5 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000005858 108.0
HKD2_k127_715882_0 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 361.0
HKD2_k127_715882_1 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000009694 216.0
HKD2_k127_715882_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000000001204 151.0
HKD2_k127_715882_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000003789 137.0
HKD2_k127_715882_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000005689 135.0
HKD2_k127_715882_5 Domain of unknown function (DUF4164) - - - 0.000000000000000000001022 97.0
HKD2_k127_7227964_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 2.922e-237 739.0
HKD2_k127_7227964_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 543.0
HKD2_k127_7227964_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000002336 160.0
HKD2_k127_7227964_3 Septum formation initiator - - - 0.00000000000000000000000000001202 121.0
HKD2_k127_7273986_0 Histidine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.943e-238 756.0
HKD2_k127_7273986_1 Transcriptional regulator - - - 0.00000000000000000000000009439 108.0
HKD2_k127_7283278_0 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0 1173.0
HKD2_k127_7283278_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1062.0
HKD2_k127_7283278_2 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 329.0
HKD2_k127_7283278_3 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000007525 197.0
HKD2_k127_7283278_4 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000005891 163.0
HKD2_k127_7283278_5 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00002301 49.0
HKD2_k127_728945_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 593.0
HKD2_k127_728945_1 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000008197 177.0
HKD2_k127_728945_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000004341 57.0
HKD2_k127_7350481_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 444.0
HKD2_k127_7350481_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000007075 248.0
HKD2_k127_7350481_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000001147 151.0
HKD2_k127_74680_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009957 284.0
HKD2_k127_74680_1 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000000000000000000000000000000000000000007231 220.0
HKD2_k127_74680_2 Phage portal protein - - - 0.00000000000000000000000000000000000000000000003988 180.0
HKD2_k127_74680_3 Nitroreductase - - - 0.00000000000000000000000000000000000000001184 158.0
HKD2_k127_74680_4 rhamnose metabolic process - - - 0.00000000000000000000000000001255 121.0
HKD2_k127_74680_5 COG3293 Transposase and inactivated derivatives - - - 0.00000000000000000000000000106 117.0
HKD2_k127_74680_6 - - - - 0.00000000000000006375 80.0
HKD2_k127_74680_7 - - - - 0.0000000000000001275 88.0
HKD2_k127_74680_8 - - - - 0.000000000000001155 79.0
HKD2_k127_74680_9 PFAM IS1 transposase - - - 0.00000001733 61.0
HKD2_k127_7512548_0 Formate dehydrogenase subunit alpha - - - 0.0 1006.0
HKD2_k127_7512548_1 PFAM DNA mismatch repair protein MutS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 527.0
HKD2_k127_7512548_10 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000001984 193.0
HKD2_k127_7512548_11 SMART DNA mismatch repair protein MutS, C-terminal - - - 0.00000000000000000000000000000000000005476 150.0
HKD2_k127_7512548_12 - - - - 0.000000000000000000000002387 105.0
HKD2_k127_7512548_13 - - - - 0.000000000000000722 86.0
HKD2_k127_7512548_14 - - - - 0.00000000000227 70.0
HKD2_k127_7512548_15 - - - - 0.000000000003026 70.0
HKD2_k127_7512548_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
HKD2_k127_7512548_3 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 461.0
HKD2_k127_7512548_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 445.0
HKD2_k127_7512548_5 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 385.0
HKD2_k127_7512548_6 AAA domain, putative AbiEii toxin, Type IV TA system K02074,K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 373.0
HKD2_k127_7512548_7 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 363.0
HKD2_k127_7512548_8 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 344.0
HKD2_k127_7512548_9 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000003224 196.0
HKD2_k127_75585_0 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 515.0
HKD2_k127_75585_1 FAD binding domain K00480 - 1.14.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 449.0
HKD2_k127_75585_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 360.0
HKD2_k127_75585_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 298.0
HKD2_k127_75585_4 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000000000000000367 154.0
HKD2_k127_75585_5 Zinc-finger domain - - - 0.0000000000000000000000000000000000004565 141.0
HKD2_k127_75585_6 ABC transporter K02049 - - 0.0000000000000000000000002719 110.0
HKD2_k127_75585_7 Protein of unknown function (DUF2892) - - - 0.00000000000000262 78.0
HKD2_k127_7667319_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 8.252e-247 767.0
HKD2_k127_7667319_1 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 555.0
HKD2_k127_7667319_2 4-hydroxybenzoate K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 481.0
HKD2_k127_7667319_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000005912 245.0
HKD2_k127_7667319_4 - - - - 0.00000001276 63.0
HKD2_k127_7672982_0 Belongs to the peptidase S16 family - - - 3.455e-320 999.0
HKD2_k127_7672982_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.152e-276 857.0
HKD2_k127_7672982_10 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 381.0
HKD2_k127_7672982_11 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 361.0
HKD2_k127_7672982_12 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 338.0
HKD2_k127_7672982_13 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 348.0
HKD2_k127_7672982_14 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 290.0
HKD2_k127_7672982_15 Dienelactone hydrolase family K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 286.0
HKD2_k127_7672982_16 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004444 254.0
HKD2_k127_7672982_17 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000001954 226.0
HKD2_k127_7672982_18 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000001903 200.0
HKD2_k127_7672982_19 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000009394 202.0
HKD2_k127_7672982_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.117e-244 770.0
HKD2_k127_7672982_20 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000008723 173.0
HKD2_k127_7672982_21 - - - - 0.0000000000000000001563 99.0
HKD2_k127_7672982_3 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 8.898e-227 710.0
HKD2_k127_7672982_4 DNA polymerase beta thumb K02347 - - 3.204e-216 684.0
HKD2_k127_7672982_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - - 6.663e-203 642.0
HKD2_k127_7672982_6 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 572.0
HKD2_k127_7672982_7 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 451.0
HKD2_k127_7672982_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 435.0
HKD2_k127_7672982_9 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 434.0
HKD2_k127_7691152_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0 1279.0
HKD2_k127_7691152_1 Protein of unknown function - - - 0.0 1058.0
HKD2_k127_7691152_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 555.0
HKD2_k127_7691152_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 503.0
HKD2_k127_7691152_4 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 469.0
HKD2_k127_7691152_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 250.0
HKD2_k127_7691152_6 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000003509 224.0
HKD2_k127_7723277_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1178.0
HKD2_k127_7723277_1 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 5.833e-222 704.0
HKD2_k127_7723277_10 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000007504 151.0
HKD2_k127_7723277_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000002321 148.0
HKD2_k127_7723277_12 - - - - 0.00000000000000000000000000000000008295 137.0
HKD2_k127_7723277_13 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000003699 139.0
HKD2_k127_7723277_2 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 472.0
HKD2_k127_7723277_3 radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 456.0
HKD2_k127_7723277_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941,K18824 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 371.0
HKD2_k127_7723277_5 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
HKD2_k127_7723277_6 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002423 256.0
HKD2_k127_7723277_7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.0000000000000000000000000000000000000000000000000001021 194.0
HKD2_k127_7723277_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000000000008241 188.0
HKD2_k127_7723277_9 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000000000000003425 161.0
HKD2_k127_7732353_0 MmgE/PrpD family - - - 5.052e-238 743.0
HKD2_k127_7732353_1 Binding-protein-dependent transport system inner membrane component K02011 - - 7.626e-238 747.0
HKD2_k127_7732353_2 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 542.0
HKD2_k127_7732353_3 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 518.0
HKD2_k127_7732353_4 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 455.0
HKD2_k127_7732353_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 372.0
HKD2_k127_7732353_6 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 381.0
HKD2_k127_7732353_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 359.0
HKD2_k127_7732353_8 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 297.0
HKD2_k127_7757315_0 Domain of unknown function (DUF4175) - - - 1.174e-298 938.0
HKD2_k127_7757315_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 2.09e-206 648.0
HKD2_k127_7757315_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 397.0
HKD2_k127_7757315_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000003652 155.0
HKD2_k127_7757315_4 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000006925 134.0
HKD2_k127_7757315_5 Prokaryotic lipoprotein-attachment site - - - 0.000001734 56.0
HKD2_k127_7767497_0 tRNA synthetases class I (C) catalytic domain K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.78e-196 623.0
HKD2_k127_7767497_1 Acetyltransferase (GNAT) domain K03830 - - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
HKD2_k127_7767497_2 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000003692 190.0
HKD2_k127_7767497_3 - - - - 0.00000000000000000000000001443 112.0
HKD2_k127_7767497_4 - - - - 0.0000000000000000007096 93.0
HKD2_k127_7767497_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000001834 85.0
HKD2_k127_7767497_6 - - - - 0.000003246 57.0
HKD2_k127_7770451_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 5.292e-297 924.0
HKD2_k127_7770451_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 1.112e-222 710.0
HKD2_k127_7770451_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 295.0
HKD2_k127_7770451_11 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 293.0
HKD2_k127_7770451_12 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002233 252.0
HKD2_k127_7770451_13 COG3039 Transposase and inactivated derivatives, IS5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006131 242.0
HKD2_k127_7770451_14 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000004799 242.0
HKD2_k127_7770451_15 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004375 232.0
HKD2_k127_7770451_16 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000002156 226.0
HKD2_k127_7770451_17 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000006634 203.0
HKD2_k127_7770451_18 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000000000000001558 127.0
HKD2_k127_7770451_19 Protein of unknown function (DUF1460) - - - 0.000000000000000000000005982 111.0
HKD2_k127_7770451_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 536.0
HKD2_k127_7770451_20 - - - - 0.00000000000001258 78.0
HKD2_k127_7770451_21 - - - - 0.000000000003076 72.0
HKD2_k127_7770451_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 507.0
HKD2_k127_7770451_4 Catechol dioxygenase N terminus K03381 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006725,GO:0008150,GO:0008152,GO:0008199,GO:0009056,GO:0009712,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0018576,GO:0018958,GO:0019114,GO:0019336,GO:0019439,GO:0019614,GO:0019615,GO:0042952,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.13.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 430.0
HKD2_k127_7770451_5 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 426.0
HKD2_k127_7770451_6 transcriptional regulator, winged helix family K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 361.0
HKD2_k127_7770451_7 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 337.0
HKD2_k127_7770451_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 320.0
HKD2_k127_7770451_9 2-keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 314.0
HKD2_k127_7790512_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.794e-314 973.0
HKD2_k127_7790512_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 526.0
HKD2_k127_7790512_10 - - - - 0.00000000000000000000000000002708 120.0
HKD2_k127_7790512_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 439.0
HKD2_k127_7790512_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 354.0
HKD2_k127_7790512_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 354.0
HKD2_k127_7790512_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 345.0
HKD2_k127_7790512_6 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 354.0
HKD2_k127_7790512_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 294.0
HKD2_k127_7790512_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000007343 214.0
HKD2_k127_7790512_9 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000008571 209.0
HKD2_k127_7796460_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 377.0
HKD2_k127_7796460_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 311.0
HKD2_k127_7796460_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000007966 199.0
HKD2_k127_7796460_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000001104 158.0
HKD2_k127_7796460_4 Peptidase family M23 - - - 0.0000000000000351 79.0
HKD2_k127_7796834_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 424.0
HKD2_k127_7796834_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 423.0
HKD2_k127_7796834_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000127 163.0
HKD2_k127_7796834_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001168 152.0
HKD2_k127_7796834_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000003293 157.0
HKD2_k127_7796834_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000472 135.0
HKD2_k127_7796834_14 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000004527 121.0
HKD2_k127_7796834_15 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000008089 99.0
HKD2_k127_7796834_16 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000009802 92.0
HKD2_k127_7796834_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 320.0
HKD2_k127_7796834_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 289.0
HKD2_k127_7796834_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004404 271.0
HKD2_k127_7796834_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000009302 237.0
HKD2_k127_7796834_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002028 226.0
HKD2_k127_7796834_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001663 222.0
HKD2_k127_7796834_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003077 207.0
HKD2_k127_7796834_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000001696 172.0
HKD2_k127_7798276_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.664e-194 625.0
HKD2_k127_7798276_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 355.0
HKD2_k127_7798276_2 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000717 236.0
HKD2_k127_7798276_3 Protein of unknown function (DUF1036) - - - 0.0000000000000000000000000000000000000000000000000000000000000363 218.0
HKD2_k127_7798276_4 TRAP transporter, solute receptor (TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000002135 189.0
HKD2_k127_7798276_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000009893 147.0
HKD2_k127_7798276_6 Major facilitator Superfamily K08177 - - 0.00000000000000000000000000000004814 130.0
HKD2_k127_7798276_7 Protein of unknown function (DUF1036) - - - 0.000000000000000000001757 96.0
HKD2_k127_7798276_8 Protein of unknown function (DUF1036) - - - 0.00003529 49.0
HKD2_k127_7811708_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 9.444e-204 638.0
HKD2_k127_7811708_1 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 531.0
HKD2_k127_7811708_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 504.0
HKD2_k127_7811708_3 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 469.0
HKD2_k127_7811708_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 376.0
HKD2_k127_7811708_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
HKD2_k127_7811708_6 Major facilitator Superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 307.0
HKD2_k127_7847763_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1128.0
HKD2_k127_7847763_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 413.0
HKD2_k127_7847763_2 SmpA / OmlA family - - - 0.0000000000000000000000000000000000000000000000000002878 190.0
HKD2_k127_7847763_3 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000087 164.0
HKD2_k127_7847763_4 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000549 98.0
HKD2_k127_7847763_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000001197 87.0
HKD2_k127_7847763_6 Ubiquinol-cytochrome C chaperone K17662 - - 0.0001283 47.0
HKD2_k127_7861552_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 567.0
HKD2_k127_7861552_1 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000008209 180.0
HKD2_k127_7866434_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.193e-214 676.0
HKD2_k127_7866434_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 473.0
HKD2_k127_7866434_2 nucleoside-triphosphate diphosphatase activity K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 368.0
HKD2_k127_7866434_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001267 231.0
HKD2_k127_7866434_4 Low molecular weight phosphotyrosine protein phosphatase K01104,K03741 - 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000005538 222.0
HKD2_k127_7866434_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009532 235.0
HKD2_k127_7866434_6 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000004877 87.0
HKD2_k127_7866434_7 Resolvase - - - 0.000000005963 58.0
HKD2_k127_7872880_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 317.0
HKD2_k127_7872880_1 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 327.0
HKD2_k127_7872880_2 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
HKD2_k127_7872880_3 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000003821 168.0
HKD2_k127_7872880_4 ABC-type nitrate sulfonate bicarbonate transport system permease component K15552 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010438,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0042908,GO:0042910,GO:0042918,GO:0042959,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071496,GO:0071944 - 0.00000000000000000000000000000000005898 139.0
HKD2_k127_7872880_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K15553 - - 0.00000000008069 73.0
HKD2_k127_7896155_0 MoeA C-terminal region (domain IV) - - - 1.553e-246 777.0
HKD2_k127_7896155_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 380.0
HKD2_k127_7896155_2 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 303.0
HKD2_k127_7896155_3 MoeA domain protein domain I and II - - - 0.00000000000000000000000000000000000000000000000000000000000002185 229.0
HKD2_k127_7896155_4 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000111 204.0
HKD2_k127_7896155_5 Sulfurtransferase TusA K04085 - - 0.000000000000000000002228 98.0
HKD2_k127_7939410_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 570.0
HKD2_k127_7939410_1 Zinc-binding dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 491.0
HKD2_k127_7939410_10 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000003859 145.0
HKD2_k127_7939410_2 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 437.0
HKD2_k127_7939410_3 Cell Wall Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 380.0
HKD2_k127_7939410_4 glycosylase i K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 329.0
HKD2_k127_7939410_5 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 306.0
HKD2_k127_7939410_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002708 286.0
HKD2_k127_7939410_7 protein tyrosine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000001611 213.0
HKD2_k127_7939410_8 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000002511 183.0
HKD2_k127_7939410_9 - - - - 0.00000000000000000000000000000000000000000003222 168.0
HKD2_k127_7959463_0 Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 376.0
HKD2_k127_7959463_1 benzoate-CoA ligase K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 349.0
HKD2_k127_7959463_2 COG1846 Transcriptional regulators - - - 0.0000000000000000000000000000000000004632 152.0
HKD2_k127_7962109_0 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 390.0
HKD2_k127_7962109_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 312.0
HKD2_k127_796581_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 595.0
HKD2_k127_796581_1 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 433.0
HKD2_k127_796581_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 383.0
HKD2_k127_796581_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 317.0
HKD2_k127_796581_4 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 316.0
HKD2_k127_796581_5 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000003839 241.0
HKD2_k127_796581_6 - - - - 0.00000000000000007213 83.0
HKD2_k127_7987542_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 564.0
HKD2_k127_7988810_0 oxidase, subunit K00425 - 1.10.3.14 7.523e-258 804.0
HKD2_k127_7988810_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.113e-235 734.0
HKD2_k127_7988810_10 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 392.0
HKD2_k127_7988810_11 PFAM Prokaryotic protein of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 367.0
HKD2_k127_7988810_12 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 308.0
HKD2_k127_7988810_13 amidohydrolase 2 K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003917 271.0
HKD2_k127_7988810_14 Invasion associated locus B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 265.0
HKD2_k127_7988810_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008307 259.0
HKD2_k127_7988810_16 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000332 258.0
HKD2_k127_7988810_17 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.000000000000000000000000000000000000000000000000000000000000000000001796 249.0
HKD2_k127_7988810_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000002894 229.0
HKD2_k127_7988810_19 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000005917 230.0
HKD2_k127_7988810_2 HpcH/HpaI aldolase/citrate lyase family K08691 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25 2.352e-196 615.0
HKD2_k127_7988810_20 - - - - 0.00000000000000000000000000000000000000000001382 172.0
HKD2_k127_7988810_21 Hemimethylated DNA-binding protein YccV like K11940 - - 0.00000000000000000000000000000000000000000002943 163.0
HKD2_k127_7988810_22 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000002622 149.0
HKD2_k127_7988810_23 - - - - 0.00000000000000000000000391 105.0
HKD2_k127_7988810_24 Urate oxidase N-terminal - - - 0.00000000000000000000002042 104.0
HKD2_k127_7988810_25 - - - - 0.0000000000000000001202 97.0
HKD2_k127_7988810_26 Domain of unknown function (DUF4336) - - - 0.000000000000000000889 87.0
HKD2_k127_7988810_28 Membrane bound YbgT-like protein K00424 - 1.10.3.14 0.000000000008715 65.0
HKD2_k127_7988810_29 His Kinase A (phosphoacceptor) domain - - - 0.000000002033 62.0
HKD2_k127_7988810_3 Aminotransferase class-III K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 599.0
HKD2_k127_7988810_31 - - - - 0.000007682 55.0
HKD2_k127_7988810_4 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 541.0
HKD2_k127_7988810_5 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 506.0
HKD2_k127_7988810_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 480.0
HKD2_k127_7988810_7 FAD binding domain K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 453.0
HKD2_k127_7988810_8 carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 446.0
HKD2_k127_7988810_9 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 417.0
HKD2_k127_7993197_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.52e-227 711.0
HKD2_k127_7993197_1 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 558.0
HKD2_k127_7993197_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 318.0
HKD2_k127_7993197_3 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000002283 98.0
HKD2_k127_7993197_4 BFD domain protein 2Fe-2S -binding domain protein - - - 0.00000000000000000002118 93.0
HKD2_k127_8021698_0 acyl-CoA dehydrogenase K00248,K00249,K20035 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 345.0
HKD2_k127_8021698_1 Short-chain dehydrogenase reductase SDR K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003896 279.0
HKD2_k127_8021698_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002335 251.0
HKD2_k127_8133910_0 2-hydroxymuconic semialdehyde dehydrogenase K10217 - 1.2.1.32,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 506.0
HKD2_k127_8133910_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 385.0
HKD2_k127_8133910_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 320.0
HKD2_k127_8133910_3 Cellulose biosynthesis protein BcsS - - - 0.000000000000000000000000000000003201 133.0
HKD2_k127_81631_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 1.067e-211 663.0
HKD2_k127_81631_1 Sodium/hydrogen exchanger family K03316 - - 1.52e-211 672.0
HKD2_k127_81631_2 Protein of unknown function (DUF3095) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 463.0
HKD2_k127_81631_3 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 356.0
HKD2_k127_81631_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001614 280.0
HKD2_k127_81631_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003033 259.0
HKD2_k127_81631_6 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000000000000002235 226.0
HKD2_k127_81631_8 - - - - 0.00001866 48.0
HKD2_k127_8182048_0 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
HKD2_k127_8182048_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 471.0
HKD2_k127_8182048_2 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 406.0
HKD2_k127_8182048_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 349.0
HKD2_k127_8182048_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 334.0
HKD2_k127_8182048_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000006892 71.0
HKD2_k127_8184496_0 UvrD-like helicase C-terminal domain K01144 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 593.0
HKD2_k127_8184496_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 586.0
HKD2_k127_8184496_2 enoyl-CoA hydratase isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 358.0
HKD2_k127_8184496_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004239 250.0
HKD2_k127_8184496_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000008367 147.0
HKD2_k127_8205192_0 Sugar (and other) transporter - - - 9.748e-272 846.0
HKD2_k127_8205192_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 337.0
HKD2_k127_8205681_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1405.0
HKD2_k127_8205681_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 411.0
HKD2_k127_8205681_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 355.0
HKD2_k127_8205681_3 Pyrogallol hydroxytransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 349.0
HKD2_k127_8205681_4 KR domain K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 291.0
HKD2_k127_8206086_0 PFAM AMP-dependent synthetase and ligase K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 563.0
HKD2_k127_8206086_1 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 342.0
HKD2_k127_8206086_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002939 282.0
HKD2_k127_8206086_3 AMP-binding enzyme C-terminal domain K00666,K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000007785 213.0
HKD2_k127_8298916_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 9.283e-264 818.0
HKD2_k127_8298916_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 6.144e-205 647.0
HKD2_k127_8298916_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
HKD2_k127_8298916_3 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008376 252.0
HKD2_k127_8298916_4 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002015 248.0
HKD2_k127_8298916_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000004639 81.0
HKD2_k127_8298916_6 - - - - 0.000000000000007394 83.0
HKD2_k127_8299708_0 Acetyl-coenzyme A synthetase N-terminus K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 1.54e-200 627.0
HKD2_k127_8299708_1 Protein of unknown function (DUF1013) K09987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 323.0
HKD2_k127_8299708_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 325.0
HKD2_k127_8299708_3 Excinuclease ABC, C subunit K07461 - - 0.000000000000000000000001798 103.0
HKD2_k127_8299708_4 Excinuclease ABC, C subunit K07461 - - 0.00000001109 64.0
HKD2_k127_8347641_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 390.0
HKD2_k127_8347641_1 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002303 235.0
HKD2_k127_8347641_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000002701 191.0
HKD2_k127_840526_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 8.566e-267 825.0
HKD2_k127_840526_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 507.0
HKD2_k127_840526_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 335.0
HKD2_k127_8419468_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 8.852e-203 647.0
HKD2_k127_8419468_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001187 245.0
HKD2_k127_8470650_0 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 602.0
HKD2_k127_8470650_1 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 387.0
HKD2_k127_8470650_2 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000001034 186.0
HKD2_k127_8470650_3 Protein of unknown function (DUF2927) - - - 0.000000000000000000000000000000000000004522 158.0
HKD2_k127_850674_0 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 551.0
HKD2_k127_850674_1 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 409.0
HKD2_k127_850674_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
HKD2_k127_850674_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 301.0
HKD2_k127_850674_4 FR47-like protein K00657 - 2.3.1.57 0.000000000000000000000000000000000000000000000000000000000000000000004289 244.0
HKD2_k127_850674_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000002193 196.0
HKD2_k127_850674_6 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000005225 76.0
HKD2_k127_8551862_0 Histidine kinase - - - 1.682e-203 643.0
HKD2_k127_8551862_1 Cytochrome c-type biogenesis protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 437.0
HKD2_k127_8551862_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 330.0
HKD2_k127_8551862_3 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000101 221.0
HKD2_k127_8551862_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000003117 199.0
HKD2_k127_86361_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 509.0
HKD2_k127_86361_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 298.0
HKD2_k127_86361_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 299.0
HKD2_k127_8644606_0 benzoate-CoA ligase K04105 - 6.2.1.25,6.2.1.27 6.34e-253 788.0
HKD2_k127_8644606_1 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 557.0
HKD2_k127_8644606_2 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 511.0
HKD2_k127_8644606_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 518.0
HKD2_k127_8644606_4 KR domain K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 293.0
HKD2_k127_8644606_5 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007469 277.0
HKD2_k127_8644606_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001022 272.0
HKD2_k127_8644606_7 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 0.000000000000000000000000000000000000000000006598 168.0
HKD2_k127_864894_0 transport system fused permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 590.0
HKD2_k127_864894_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 443.0
HKD2_k127_864894_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 422.0
HKD2_k127_864894_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004255 260.0
HKD2_k127_864894_4 transport system fused permease components - - - 0.000002293 52.0
HKD2_k127_8650580_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1127.0
HKD2_k127_8650580_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 8.617e-252 790.0
HKD2_k127_8650580_10 - - - - 0.000000000000000000000000000000000000000000003514 172.0
HKD2_k127_8650580_11 COG0563 Adenylate kinase and related - - - 0.0000000000000000000000000000000000002951 143.0
HKD2_k127_8650580_12 ParB-like nuclease domain - - - 0.00000000000000000000000003285 112.0
HKD2_k127_8650580_13 COGs COG0563 Adenylate kinase and related kinase - - - 0.0000000000000001443 82.0
HKD2_k127_8650580_14 - - - - 0.000000000000003103 84.0
HKD2_k127_8650580_2 May be involved in recombinational repair of damaged DNA K03631 - - 2.71e-235 740.0
HKD2_k127_8650580_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 529.0
HKD2_k127_8650580_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 380.0
HKD2_k127_8650580_5 drug resistance transporter, Bcr CflA K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 334.0
HKD2_k127_8650580_6 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002276 256.0
HKD2_k127_8650580_7 - K11477 - - 0.000000000000000000000000000000000000000000000000000000000004482 214.0
HKD2_k127_8650580_8 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000002032 212.0
HKD2_k127_8650580_9 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000005728 192.0
HKD2_k127_8673657_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 424.0
HKD2_k127_8673657_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 302.0
HKD2_k127_8673657_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001298 271.0
HKD2_k127_8673657_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009794 278.0
HKD2_k127_8673657_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K01860,K19802 - 5.1.1.20,5.5.1.1,5.5.1.7 0.000000000000000000000000000000000000000000000000000001497 205.0
HKD2_k127_8673657_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000001566 86.0
HKD2_k127_8673657_6 ATPases associated with a variety of cellular activities - - - 0.000000000000004399 76.0
HKD2_k127_86988_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1121.0
HKD2_k127_86988_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.308e-293 918.0
HKD2_k127_86988_10 - - - - 0.00000000000000000000000003265 117.0
HKD2_k127_86988_11 PFAM DoxX family protein K15977 - - 0.00000000000000008739 86.0
HKD2_k127_86988_12 DoxX K15977 - - 0.0000000000005755 71.0
HKD2_k127_86988_13 DinB family - - - 0.0007058 43.0
HKD2_k127_86988_2 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 3.096e-259 814.0
HKD2_k127_86988_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 4.174e-215 678.0
HKD2_k127_86988_4 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 4.844e-205 642.0
HKD2_k127_86988_5 Permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 460.0
HKD2_k127_86988_6 Permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 411.0
HKD2_k127_86988_7 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 291.0
HKD2_k127_86988_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001252 238.0
HKD2_k127_86988_9 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000009619 230.0
HKD2_k127_8753440_0 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 449.0
HKD2_k127_8753440_1 Inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000006249 241.0
HKD2_k127_8753440_2 Response regulator receiver domain K13589 - - 0.0000000000000000000000000000000000000000000000000000000000005987 214.0
HKD2_k127_8753440_3 Belongs to the 'phage' integrase family - - - 0.000006607 51.0
HKD2_k127_8821588_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1777.0
HKD2_k127_8830973_0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 591.0
HKD2_k127_8830973_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 466.0
HKD2_k127_8830973_3 Belongs to the 'phage' integrase family - - - 0.0009174 44.0
HKD2_k127_8870973_0 Ftsk_gamma K03466 - - 2.646e-242 752.0
HKD2_k127_8870973_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 412.0
HKD2_k127_8870973_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 289.0
HKD2_k127_8870973_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000004616 83.0
HKD2_k127_8911627_0 Belongs to the thiolase family K07823 - 2.3.1.174 6.424e-206 647.0
HKD2_k127_8911627_1 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 414.0
HKD2_k127_8911627_2 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 416.0
HKD2_k127_8911627_3 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000001692 190.0
HKD2_k127_8911627_4 Dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000001045 121.0
HKD2_k127_8956463_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1794.0
HKD2_k127_8956463_1 4Fe-4S binding domain - - - 2.828e-308 958.0
HKD2_k127_8956463_10 Molybdopterin guanine dinucleotide synthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000002791 222.0
HKD2_k127_8956463_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000001083 196.0
HKD2_k127_8956463_12 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000000000000000000000000002739 198.0
HKD2_k127_8956463_13 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000001768 198.0
HKD2_k127_8956463_14 - - - - 0.000000000000000000000000000000000000000000000000005079 202.0
HKD2_k127_8956463_15 Protein of unknown function (DUF3306) - - - 0.0000000000000000000000000000002412 131.0
HKD2_k127_8956463_2 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 477.0
HKD2_k127_8956463_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 462.0
HKD2_k127_8956463_4 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 421.0
HKD2_k127_8956463_5 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 422.0
HKD2_k127_8956463_6 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 339.0
HKD2_k127_8956463_7 WD domain, G-beta repeat K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 332.0
HKD2_k127_8956463_8 Biotin/lipoate A/B protein ligase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 299.0
HKD2_k127_8956463_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000008628 260.0
HKD2_k127_8961229_0 Aldehyde dehydrogenase family K00130 - 1.2.1.8 3.122e-224 704.0
HKD2_k127_8984313_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1307.0
HKD2_k127_8984313_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1055.0
HKD2_k127_8984313_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.206e-290 900.0
HKD2_k127_8984313_3 Choline dehydrogenase K00108 - 1.1.99.1 5.527e-253 791.0
HKD2_k127_8984313_4 Transporter associated domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 508.0
HKD2_k127_8984313_5 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 351.0
HKD2_k127_8984313_6 Penicillin-insensitive murein endopeptidase K07261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 342.0
HKD2_k127_8984313_7 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000818 175.0
HKD2_k127_8984313_8 - - - - 0.0000000000000000000000000000004271 129.0
HKD2_k127_9000076_0 Pyridine nucleotide-disulphide oxidoreductase - - - 2.564e-303 935.0
HKD2_k127_9000076_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 578.0
HKD2_k127_9000076_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 523.0
HKD2_k127_9000076_3 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000001173 242.0
HKD2_k127_9000076_4 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000001347 186.0
HKD2_k127_9000076_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000001022 141.0
HKD2_k127_9000076_6 Protein of unknown function (DUF2892) - - - 0.000000000000000000000001709 107.0
HKD2_k127_9000076_7 - - - - 0.0001407 48.0
HKD2_k127_9002060_0 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 575.0
HKD2_k127_9002060_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
HKD2_k127_9002060_10 - - - - 0.000000000000000000000000000000008655 131.0
HKD2_k127_9002060_11 YCII-related domain K09780 - - 0.000000002484 59.0
HKD2_k127_9002060_12 YCII-related domain K09780 - - 0.00001215 53.0
HKD2_k127_9002060_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 498.0
HKD2_k127_9002060_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 483.0
HKD2_k127_9002060_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 294.0
HKD2_k127_9002060_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001159 268.0
HKD2_k127_9002060_6 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003881 252.0
HKD2_k127_9002060_7 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000002051 159.0
HKD2_k127_9002060_8 Phasin protein - - - 0.0000000000000000000000000000000001188 136.0
HKD2_k127_9002060_9 - - - - 0.000000000000000000000000000000001565 133.0
HKD2_k127_9019509_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.004e-219 688.0
HKD2_k127_9019509_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000002021 212.0
HKD2_k127_9039072_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 569.0
HKD2_k127_9039072_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 487.0
HKD2_k127_9039072_10 COG2755 Lysophospholipase L1 and related K10804 - 3.1.1.5 0.0000001764 57.0
HKD2_k127_9039072_2 MotA/TolQ/ExbB proton channel family K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 404.0
HKD2_k127_9039072_3 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 318.0
HKD2_k127_9039072_4 EcsC protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004487 269.0
HKD2_k127_9039072_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000001626 226.0
HKD2_k127_9039072_6 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000003502 218.0
HKD2_k127_9039072_7 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000000001283 212.0
HKD2_k127_9039072_8 Cell division and transport-associated protein TolA - - - 0.000000000000000000000000000000000000000000000000000000005889 211.0
HKD2_k127_9039072_9 Protein of unknown function (DUF2852) - - - 0.00000000000000000000000000000000000000000000004446 174.0
HKD2_k127_9039928_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 9.147e-268 833.0
HKD2_k127_9039928_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 1.191e-228 715.0
HKD2_k127_9039928_10 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000000000000000101 179.0
HKD2_k127_9039928_11 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000002601 159.0
HKD2_k127_9039928_12 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000003605 158.0
HKD2_k127_9039928_16 Domain of unknown function (DUF1127) - - - 0.000000002268 61.0
HKD2_k127_9039928_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 503.0
HKD2_k127_9039928_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 422.0
HKD2_k127_9039928_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 353.0
HKD2_k127_9039928_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 289.0
HKD2_k127_9039928_6 Squalene/phytoene synthase K02291,K18163 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000003453 258.0
HKD2_k127_9039928_7 N-terminal half of MaoC dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0071704 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000008861 241.0
HKD2_k127_9039928_8 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000009382 226.0
HKD2_k127_9039928_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000001285 229.0
HKD2_k127_9047113_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.238e-318 983.0
HKD2_k127_9047113_1 Dehydratase family K01687,K22186 - 4.2.1.82,4.2.1.9 1.401e-270 842.0
HKD2_k127_9047113_2 AMP-binding enzyme C-terminal domain K00666,K02182,K20034 - 6.2.1.44,6.2.1.48 3.384e-224 701.0
HKD2_k127_9047113_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 497.0
HKD2_k127_9047113_4 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 445.0
HKD2_k127_9047113_5 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K09968 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 284.0
HKD2_k127_9047113_6 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 243.0
HKD2_k127_9063281_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 572.0
HKD2_k127_9063281_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 448.0
HKD2_k127_9063281_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 359.0
HKD2_k127_9063281_3 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
HKD2_k127_9063281_4 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002192 272.0
HKD2_k127_9063281_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000007804 261.0
HKD2_k127_9063281_6 - - - - 0.00000000000000000000000000000000000000000000000004389 188.0
HKD2_k127_9063281_7 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000001459 99.0
HKD2_k127_9063281_8 Endonuclease/Exonuclease/phosphatase family - - - 0.00000004765 57.0
HKD2_k127_9073851_0 DNA methylase K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 459.0
HKD2_k127_9073851_1 FES K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 458.0
HKD2_k127_9073851_2 DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000002365 228.0
HKD2_k127_9073851_3 Protein of unknown function (DUF721) - - - 0.000000000000000000000000000000000000000000000000007174 184.0
HKD2_k127_9110383_0 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 504.0
HKD2_k127_9131076_0 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 587.0
HKD2_k127_9131076_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 507.0
HKD2_k127_9131076_10 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
HKD2_k127_9131076_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008467 245.0
HKD2_k127_9131076_12 Cupin domain - - - 0.000000000000000000000001561 116.0
HKD2_k127_9131076_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 429.0
HKD2_k127_9131076_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 420.0
HKD2_k127_9131076_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 384.0
HKD2_k127_9131076_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 387.0
HKD2_k127_9131076_6 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K15063 - 4.1.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 370.0
HKD2_k127_9131076_7 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 342.0
HKD2_k127_9131076_8 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 345.0
HKD2_k127_9131076_9 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 322.0
HKD2_k127_9134807_0 Belongs to the UbiD family K03182 - 4.1.1.98 7.325e-279 867.0
HKD2_k127_9134807_1 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 381.0
HKD2_k127_9134807_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000054 240.0
HKD2_k127_9134807_3 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000001962 84.0
HKD2_k127_9148633_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 487.0
HKD2_k127_9148633_1 Histidyl-tRNA synthetase K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 486.0
HKD2_k127_9148633_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000011 170.0
HKD2_k127_9153479_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 344.0
HKD2_k127_9153479_1 Amidohydrolase K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 298.0
HKD2_k127_9160937_0 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 430.0
HKD2_k127_9160937_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002307 267.0
HKD2_k127_9160937_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000248 229.0
HKD2_k127_9160937_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000005476 200.0
HKD2_k127_9165308_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 345.0
HKD2_k127_9165308_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 289.0
HKD2_k127_9165308_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000005114 58.0
HKD2_k127_9195676_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1122.0
HKD2_k127_9195676_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 499.0
HKD2_k127_9195676_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 471.0
HKD2_k127_919900_0 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 419.0
HKD2_k127_919900_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 404.0
HKD2_k127_919900_2 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 310.0
HKD2_k127_919900_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001127 267.0
HKD2_k127_919900_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000005025 184.0
HKD2_k127_923130_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.907e-246 764.0
HKD2_k127_923130_1 AMP-binding enzyme K12508 - 6.2.1.34 4.181e-225 713.0
HKD2_k127_923130_10 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000001519 71.0
HKD2_k127_923130_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 554.0
HKD2_k127_923130_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 350.0
HKD2_k127_923130_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 351.0
HKD2_k127_923130_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 287.0
HKD2_k127_923130_6 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000000003066 169.0
HKD2_k127_923130_7 Thioesterase-like superfamily K01075 - 3.1.2.23 0.00000000000000000000000000000000002774 139.0
HKD2_k127_923130_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000001238 136.0
HKD2_k127_923130_9 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000001682 94.0
HKD2_k127_9257039_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 257.0
HKD2_k127_9257039_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000002704 215.0
HKD2_k127_9257039_2 ABC transporter K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000002772 206.0
HKD2_k127_9261095_0 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 336.0
HKD2_k127_9261095_1 glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003461 258.0
HKD2_k127_9261095_2 phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000001211 217.0
HKD2_k127_9301320_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 9.223e-196 616.0
HKD2_k127_9301320_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 450.0
HKD2_k127_9301320_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 384.0
HKD2_k127_9301320_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 372.0
HKD2_k127_9301320_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 367.0
HKD2_k127_9301320_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 318.0
HKD2_k127_9301320_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 314.0
HKD2_k127_9301320_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000002149 199.0
HKD2_k127_9301320_9 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.00001242 49.0
HKD2_k127_9316461_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 6.789e-300 944.0
HKD2_k127_9316461_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 4.702e-255 795.0
HKD2_k127_9316461_10 Recombinase zinc beta ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
HKD2_k127_9316461_11 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000003049 171.0
HKD2_k127_9316461_12 MAPEG family - - - 0.00000000000000000000000000000000000000000002741 164.0
HKD2_k127_9316461_13 DDE superfamily endonuclease - - - 0.000000000000001689 75.0
HKD2_k127_9316461_2 Major Facilitator Superfamily - - - 1.476e-194 618.0
HKD2_k127_9316461_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 597.0
HKD2_k127_9316461_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 568.0
HKD2_k127_9316461_5 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 434.0
HKD2_k127_9316461_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 396.0
HKD2_k127_9316461_7 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 317.0
HKD2_k127_9316461_8 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002657 283.0
HKD2_k127_9316461_9 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302,K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000003119 229.0
HKD2_k127_9350483_0 epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 473.0
HKD2_k127_9350483_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 422.0
HKD2_k127_9350483_2 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 341.0
HKD2_k127_9350483_3 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 338.0
HKD2_k127_9350483_4 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007614 278.0
HKD2_k127_9350483_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002749 253.0
HKD2_k127_9350483_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K16422 - 1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000005312 238.0
HKD2_k127_9431239_0 DEAD/H associated K03724 - - 0.0 1285.0
HKD2_k127_9431239_1 Acyl-CoA dehydrogenase N terminal K00249 - 1.3.8.7 4.438e-300 929.0
HKD2_k127_9431239_2 Sel1-like repeats. K07126,K13582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 536.0
HKD2_k127_9431239_3 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008597 284.0
HKD2_k127_9431239_4 - - - - 0.00000000000000000000000000000001337 128.0
HKD2_k127_9512221_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.56e-322 994.0
HKD2_k127_9512221_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 1.174e-197 621.0
HKD2_k127_9512221_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000601 172.0
HKD2_k127_9512221_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000000001255 130.0
HKD2_k127_9512221_12 Lipocalin-like domain - - - 0.000000000000000000000000001338 117.0
HKD2_k127_9512221_13 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000005594 63.0
HKD2_k127_9512221_14 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00001035 48.0
HKD2_k127_9512221_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 539.0
HKD2_k127_9512221_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 488.0
HKD2_k127_9512221_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 451.0
HKD2_k127_9512221_5 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 409.0
HKD2_k127_9512221_6 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 338.0
HKD2_k127_9512221_7 hemolysin K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 294.0
HKD2_k127_9512221_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000004333 241.0
HKD2_k127_9512221_9 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000005866 222.0
HKD2_k127_9533077_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1131.0
HKD2_k127_9533077_1 Excinuclease ABC, C subunit K07461 - - 0.000000000000000000000000001147 114.0
HKD2_k127_9533077_2 ErfK YbiS YcfS YnhG family protein - - - 0.00004961 52.0
HKD2_k127_9575322_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 539.0
HKD2_k127_9575322_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000001193 96.0
HKD2_k127_9575322_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000003207 81.0
HKD2_k127_9603603_0 Putative nucleotidyltransferase substrate binding domain K02342,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 314.0
HKD2_k127_9603603_1 - - - - 0.0000000000000000000000000000000000000000000000000000000005029 208.0
HKD2_k127_9603603_2 Histidine kinase - - - 0.000002438 49.0
HKD2_k127_96411_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1164.0
HKD2_k127_96411_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 9.206e-220 693.0
HKD2_k127_96411_10 DoxX family K15977 - - 0.000000001932 63.0
HKD2_k127_96411_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 592.0
HKD2_k127_96411_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 533.0
HKD2_k127_96411_4 Bacterial dnaA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001505 283.0
HKD2_k127_96411_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003782 269.0
HKD2_k127_96411_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004051 255.0
HKD2_k127_96411_7 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004767 256.0
HKD2_k127_96411_8 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000001416 231.0
HKD2_k127_96411_9 AI-2E family transporter - - - 0.000000000000000000012 96.0
HKD2_k127_9699803_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 607.0
HKD2_k127_9699803_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 532.0
HKD2_k127_9699803_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 337.0
HKD2_k127_9699803_3 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 272.0
HKD2_k127_9699803_4 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000002928 132.0
HKD2_k127_9699803_5 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.00000000000000000000000007346 113.0
HKD2_k127_9699803_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000001618 88.0
HKD2_k127_9699803_7 - - - - 0.000000000000000002627 92.0
HKD2_k127_973998_0 Ammonium Transporter K03320 - - 2.693e-210 666.0
HKD2_k127_973998_1 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 556.0
HKD2_k127_973998_2 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 260.0
HKD2_k127_973998_3 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000261 201.0
HKD2_k127_9759614_0 Two component transcriptional regulator, winged helix family K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 437.0
HKD2_k127_9759614_1 Histidine kinase K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 408.0
HKD2_k127_9759614_2 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 339.0
HKD2_k127_9759614_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.00000000000000000000000000000004195 129.0
HKD2_k127_9776248_0 ABC-type oligopeptide transport system periplasmic component K13893 - - 4.106e-291 905.0
HKD2_k127_9776248_1 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 353.0
HKD2_k127_9776248_2 Binding-protein-dependent transport system inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 344.0
HKD2_k127_9778318_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1129.0
HKD2_k127_9778318_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 497.0
HKD2_k127_9778318_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 477.0
HKD2_k127_9778318_3 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 343.0
HKD2_k127_9778318_4 helix_turn_helix, arabinose operon control protein K18954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 341.0
HKD2_k127_9778318_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 314.0
HKD2_k127_9778318_6 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 300.0
HKD2_k127_9778318_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001085 275.0
HKD2_k127_9778318_8 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005301 249.0
HKD2_k127_9778318_9 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000002439 204.0
HKD2_k127_9780804_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.046e-240 752.0
HKD2_k127_9780804_1 MiaB-like tRNA modifying enzyme K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 565.0
HKD2_k127_9780804_10 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000001696 205.0
HKD2_k127_9780804_11 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000005292 192.0
HKD2_k127_9780804_12 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000007865 181.0
HKD2_k127_9780804_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000008776 156.0
HKD2_k127_9780804_14 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000003391 56.0
HKD2_k127_9780804_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 456.0
HKD2_k127_9780804_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 424.0
HKD2_k127_9780804_4 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 362.0
HKD2_k127_9780804_5 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004276 285.0
HKD2_k127_9780804_6 Redoxin K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001549 274.0
HKD2_k127_9780804_7 Pyridoxamine 5'-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001653 261.0
HKD2_k127_9780804_8 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004768 241.0
HKD2_k127_9780804_9 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002364 222.0
HKD2_k127_9814362_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.175e-198 626.0
HKD2_k127_9814362_1 enoyl-CoA hydratase K01692,K05605 - 3.1.2.4,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 398.0
HKD2_k127_9814362_2 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000008774 198.0
HKD2_k127_9814362_3 - - - - 0.000000000000000000000000000000000298 145.0
HKD2_k127_9814362_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000003924 98.0
HKD2_k127_9822784_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
HKD2_k127_9822784_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000007812 149.0
HKD2_k127_9822784_2 Acyl-CoA dehydrogenase, middle domain K18244 - - 0.0000001058 56.0
HKD2_k127_9939427_0 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 343.0
HKD2_k127_9939427_1 transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007141 242.0
HKD2_k127_9948399_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 339.0
HKD2_k127_9948399_1 Sodium proton antiporter, NhaD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 265.0
HKD2_k127_9948399_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000004769 93.0
HKD2_k127_9948399_3 PAS fold - - - 0.0004929 49.0
HKD2_k127_9963765_0 Amidohydrolase K07045,K14333,K15063,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 411.0
HKD2_k127_9963765_2 - - - - 0.000000000000000000000000000000001063 131.0
HKD2_k127_9963765_3 Cold shock K03704 - - 0.000000000000000000000000001919 115.0